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Frederick Domann

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Anthony R Cyr; Michael J Hitchler; Frederick E Domann
Regulation of SOD2 in Cancer by Histone Modifications and CpG Methylation: Closing the Loop Between Redox Biology and Epigenetics.
Adam J Case; Joshua M Madsen; David K Meyerholz; David G Motto; Frederick E Domann
Manganese superoxide dismutase depletion in murine hematopoietic stem cells perturbs iron homeostasis, globin switching, and epigenetic control in erythrocyte precursor cells.
Frederick E Domann
Aberrant free radical biology is a unifying theme in the etiology and pathogenesis of major human diseases.

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All Publications

2013: Anthony R Cyr; Michael J Hitchler; Frederick E Domann
Regulation of SOD2 in Cancer by Histone Modifications and CpG Methylation: Closing the Loop Between Redox Biology and Epigenetics.
Antioxidants & redox signaling 2013;18(15):1946-55.
2013: Adam J Case; Joshua M Madsen; David K Meyerholz; David G Motto; Frederick E Domann
Manganese superoxide dismutase depletion in murine hematopoietic stem cells perturbs iron homeostasis, globin switching, and epigenetic control in erythrocyte precursor cells.
Free radical biology & medicine 2013;56():17-27.
2013: Frederick E Domann
Aberrant free radical biology is a unifying theme in the etiology and pathogenesis of major human diseases.
International journal of molecular sciences 2013;14(4):8491-5.
2012: Michael J Hitchler; Frederick E Domann
Redox regulation of the epigenetic landscape in cancer: a role for metabolic reprogramming in remodeling the epigenome.
Free radical biology & medicine 2012;53(11):2178-87.
2012: Adam J Case; Frederick E Domann
Manganese superoxide dismutase is dispensable for post-natal development and lactation in the murine mammary gland.
Free radical research 2012;46(11):1361-8.
2012: Adam J Case; Jennifer E Hrabe; James Mezhir; Brianne R O'Leary; Frederick E Domann
Rational design of a secreted enzymatically inactive mutant of extracellular superoxide dismutase.
Redox report : communications in free radical research 2012;17(6):239-45.
2012: Melissa L T Teoh-Fitzgerald; Matthew P Fitzgerald; Bernard W Futscher; Taylor J Jensen; Frederick E Domann
Genetic and epigenetic inactivation of extracellular superoxide dismutase promotes an invasive phenotype in human lung cancer by disrupting ECM homeostasis.
Molecular cancer research : MCR 2012;10(1):40-51.
2011: Anthony R Cyr; Frederick E Domann
The redox basis of epigenetic modifications: from mechanisms to functional consequences.
Antioxidants & redox signaling 2011;15(2):551-89.
2011: Nukhet Aykin-Burns; Benjamin G Slane; Annie T Y Liu; Kjerstin M Owens; Malinda S O'Malley; Brian J Smith; Frederick E Domann; Douglas R Spitz
Sensitivity to low-dose/low-LET ionizing radiation in mammalian cells harboring mutations in succinate dehydrogenase subunit C is governed by mitochondria-derived reactive oxygen species.
Radiation research 2011;175(2):150-8.
2011: Adam J Case; Jodi L McGill; Lorraine T Tygrett; Takuji Shirasawa; Douglas R Spitz; Thomas J Waldschmidt; Kevin Legge; Frederick E Domann
Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge.
Free radical biology & medicine 2011;50(3):448-58.
2011: Matthew P Fitzgerald; Francoise Gourronc; Melissa L T Teoh; Matthew J Provenzano; Adam J Case; James A Martin; Frederick E Domann
Human Chondrosarcoma Cells Acquire an Epithelial-Like Gene Expression Pattern via an Epigenetic Switch: Evidence for Mesenchymal-Epithelial Transition during Sarcomagenesis.
Sarcoma 2011;2011():598218.
2011: Trenton L Place; Matthew P Fitzgerald; Sujatha Venkataraman; Sabine U Vorrink; Adam J Case; Melissa L T Teoh; Frederick E Domann
Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells.
PloS one 2011;6(1):e14617.
2010: George W Woodfield; Yizhen Chen; Thomas B Bair; Frederick E Domann; Ronald J Weigel
Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells.
Genes, chromosomes & cancer 2010;49(10):948-62.
2010: Matthew P Fitzgerald; Joshua M Madsen; Mitchell C Coleman; Melissa L T Teoh; Scott G Westphal; Douglas R Spitz; Rafael Radi; Frederick E Domann
Transgenic biosynthesis of trypanothione protects Escherichia coli from radiation-induced toxicity.
Radiation research 2010;174(3):290-6.
2009: Disha Dayal; Sean M Martin; Kjerstin M Owens; Nukhet Aykin-Burns; Yueming Zhu; Amutha Boominathan; Debkumar Pain; Charles L Limoli; Prabhat C Goswami; Frederick E Domann; Douglas R Spitz
Mitochondrial complex II dysfunction can contribute significantly to genomic instability after exposure to ionizing radiation.
Radiation research 2009;172(6):737-45.
2009: Chompunoot Sinthupibulyakit; Kristopher Ray Grimes; Frederick E Domann; Yong Xu; Fang Fang; Wanida Ittarat; Daret K St Clair; William St Clair
p53 is an important factor for the radiosensitization effect of 2-deoxy-D-glucose.
International journal of oncology 2009;35(3):609-15.
2009: Melissa L T Teoh; Matthew P Fitzgerald; Larry W Oberley; Frederick E Domann
Overexpression of extracellular superoxide dismutase attenuates heparanase expression and inhibits breast carcinoma cell growth and invasion.
Cancer research 2009;69(15):6355-63.
2009: Michael J Hitchler; Frederick E Domann
Metabolic defects provide a spark for the epigenetic switch in cancer.
Free radical biology & medicine 2009;47(2):115-27.
2009: George W Woodfield; Michael J Hitchler; Yizhen Chen; Frederick E Domann; Ronald J Weigel
Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(11):3672-9.
2009: Lei Yu; Michael J Hitchler; Wenqing Sun; Ehab Sarsour; Prabhat C Goswami; Aloysius J Klingelhutz; Frederick E Domann
AP-2alpha Inhibits c-MYC Induced Oxidative Stress and Apoptosis in HaCaT Human Keratinocytes.
Journal of oncology 2009;2009():780874.
2009: Rui Zhao; Nong Xiang; Frederick E Domann; Weixiong Zhong
Effects of selenite and genistein on G2/M cell cycle arrest and apoptosis in human prostate cancer cells.
Nutrition and cancer 2009;61(3):397-407.
2008: Michael J Hitchler; Larry W Oberley; Frederick E Domann
Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells.
Free radical biology & medicine 2008;45(11):1573-80.
2008: Fedik Rahimov; Mary L Marazita; Axel Visel; Margaret E Cooper; Michael J Hitchler; Michele Rubini; Frederick E Domann; Manika Govil; Kaare Christensen; Camille Bille; Mads Melbye; Astanand Jugessur; Rolv T Lie; Allen J Wilcox; David R Fitzpatrick; Eric Green; Peter Anthony Mossey; Julian Little; Regine P Steegers-Theunissen; Len A Pennacchio; Brian C Schutte; Jeffrey C Murray
Disruption of an AP-2alpha binding site in an IRF6 enhancer is associated with cleft lip.
Nature genetics 2008;40(11):1341-7.
2008: Geeta Lal; Lakshmi Padmanabha; Matthew Provenzano; Matthew Fitzgerald; Jamie Weydert; Frederick E Domann
Regulation of 14-3-3sigma expression in human thyroid carcinoma is epigenetically regulated by aberrant cytosine methylation.
Cancer letters 2008;267(1):165-74.
2008: Iman M Ahmad; Maher Y Abdalla; Nukhet Aykin-Burns; Andrean L Simons; Larry W Oberley; Frederick E Domann; Douglas R Spitz
2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress.
Free radical biology & medicine 2008;44(5):826-34.
2008: George S Watts; Bernard W Futscher; Nicholas Holtan; Koen DeGeest; Frederick E Domann; Stephen L Rose
DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage.
BMC medical genomics 2008;1():47.
2007: Matthew J Provenzano; Matthew P Fitzgerald; Kimberly Krager; Frederick E Domann
Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC).
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2007;137(5):722-8.
2007: Matthew J Provenzano; Frederick E Domann
A role for epigenetics in hearing: Establishment and maintenance of auditory specific gene expression patterns.
Hearing research 2007;233(1-2):1-13.
2007: Michael J Hitchler; Frederick E Domann
An epigenetic perspective on the free radical theory of development.
Free radical biology & medicine 2007;43(7):1023-36.
2007: Matthew J Provenzano; Lei Yu; Michael J Hitchler; Matthew P Fitzgerald; Robert A Robinson; Sigrid Wayne; Mark Ver Meer; Frederick E Domann
AP-2 participates in the transcriptional control of the amyloid precursor protein (APP) gene in oral squamous cell carcinoma.
Experimental and molecular pathology 2007;83(2):277-82.
2007: Jonathan M Bock; Sarita G Menon; Prabhat C Goswami; Lori L Sinclair; Nichole S Bedford; Frederick E Domann; Douglas K Trask
Relative non-steroidal anti-inflammatory drug (NSAID) antiproliferative activity is mediated through p21-induced G1 arrest and E2F inhibition.
Molecular carcinogenesis 2007;46(10):857-64.
2007: Fiorenza Ianzini; Frederick E Domann; Elizabeth A Kosmacek; Stacia L Phillips; Michael A Mackey
Human glioblastoma U87MG cells transduced with a dominant negative p53 (TP53) adenovirus construct undergo radiation-induced mitotic catastrophe.
Radiation research 2007;168(2):183-92.
2007: Sarita G Menon; Ehab Sarsour; Amanda L Kalen; Sujatha Venkataraman; Michael J Hitchler; Frederick E Domann; Larry W Oberley; Prabhat C Goswami
Superoxide signaling mediates N-acetyl-L-cysteine-induced G1 arrest: regulatory role of cyclin D1 and manganese superoxide dismutase.
Cancer research 2007;67(13):6392-9.
2007: Jonathan M Bock; Sarita G Menon; Lori L Sinclair; Nichole S Bedford; Prabhat C Goswami; Frederick E Domann; Douglas K Trask
Celecoxib toxicity is cell cycle phase specific.
Cancer research 2007;67(8):3801-8.
2007: Van Tompkins; Jussara Hagen; April A Frazier; Tamara P Lushnikova; Matthew P Fitzgerald; Anne Di Tommaso; Veronique Ladeveze; Frederick E Domann; Christine M Eischen; Dawn E Quelle
A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability.
The Journal of biological chemistry 2007;282(2):1322-33.
2006: Lei Yu; Sujatha Venkataraman; Mitchell C Coleman; Douglas R Spitz; Philip W Wertz; Frederick E Domann
Glutathione peroxidase-1 inhibits UVA-induced AP-2alpha expression in human keratinocytes.
Biochemical and biophysical research communications 2006;351(4):1066-71.
2006: Geeta Lal; Lakshmi Padmanabha; Brian J Smith; Rachael M Nicholson; James R Howe; M Sue O'Dorisio; Frederick E Domann
RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinoma.
Cancer 2006;107(12):2752-9.
2006: Kristi Berger; Felicia Barriga; Michael J Lace; Lubomir P Turek; Gideon J Zamba; Frederick E Domann; John H Lee; Aloysius J Klingelhutz
Cervical keratinocytes containing stably replicating extrachromosomal HPV-16 are refractory to transformation by oncogenic H-Ras.
Virology 2006;356(1-2):68-78.
2006: Rui Zhao; Frederick E Domann; Weixiong Zhong
Apoptosis induced by selenomethionine and methioninase is superoxide mediated and p53 dependent in human prostate cancer cells.
Molecular cancer therapeutics 2006;5(12):3275-84.
2006: Benjamin W Darbro; K M Lee; N K Nguyen; Frederick E Domann; Aloysius J Klingelhutz
Methylation of the p16(INK4a) promoter region in telomerase immortalized human keratinocytes co-cultured with feeder cells.
Oncogene 2006;25(56):7421-33.
2006: Michael J Hitchler; Kornwipa Wikainapakul; Lei Yu; Kristy Powers; Watcharee Attatippaholkun; Frederick E Domann
Epigenetic regulation of manganese superoxide dismutase expression in human breast cancer cells.
Epigenetics : official journal of the DNA Methylation Society 2006;1(4):163-71.
2006: Lei Yu; Frederick E Domann
Rapid and direct quantitative RT-PCR method to measure promoter activity.
Biotechnology progress 2006;22(5):1461-3.
2006: H Li; George S Watts; Marc M Oshiro; Bernard W Futscher; Frederick E Domann
AP-2alpha and AP-2gamma are transcriptional targets of p53 in human breast carcinoma cells.
Oncogene 2006;25(39):5405-15.
2006: Benjamin G Slane; Nukhet Aykin-Burns; Brian J Smith; Amanda L Kalen; Prabhat C Goswami; Frederick E Domann; Douglas R Spitz
Mutation of succinate dehydrogenase subunit C results in increased O2.-, oxidative stress, and genomic instability.
Cancer research 2006;66(15):7615-20.
2006: Stephen L Rose; Matthew P Fitzgerald; Natalie O White; Michael J Hitchler; Bernard W Futscher; Koen De Geest; Frederick E Domann
Epigenetic regulation of maspin expression in human ovarian carcinoma cells.
Gynecologic oncology 2006;102(2):319-24.
2006: Farid Moussavi-Harami; Anthony V Mollano; James A Martin; Andrew Ayoob; Frederick E Domann; Steven Gitelis; Joseph A Buckwalter
Intrinsic radiation resistance in human chondrosarcoma cells.
Biochemical and biophysical research communications 2006;346(2):379-85.
2006: Jun Luo; Ling Li; Yuping Zhang; Douglas R Spitz; Garry R Buettner; Larry W Oberley; Frederick E Domann
Inactivation of primary antioxidant enzymes in mouse keratinocytes by photodynamically generated singlet oxygen.
Antioxidants & redox signaling 2006;8(7-8):1307-14.
2006: Hualei Li; Prabhat C Goswami; Frederick E Domann
AP-2gamma induces p21 expression, arrests cell cycle, and inhibits the tumor growth of human carcinoma cells.
Neoplasia (New York, N.Y.) 2006;8(7):568-77.
2006: Gang Niu; Richard D Anderson; Mark T Madsen; Michael M Graham; Larry W Oberley; Frederick E Domann
Dual-expressing adenoviral vectors encoding the sodium iodide symporter for use in noninvasive radiological imaging of therapeutic gene transfer.
Nuclear medicine and biology 2006;33(3):391-8.
2006: Rui Zhao; Nong Xiang; Frederick E Domann; Weixiong Zhong
Expression of p53 enhances selenite-induced superoxide production and apoptosis in human prostate cancer cells.
Cancer research 2006;66(4):2296-304.
2006: Kelly K Andringa; Mitchell C Coleman; Nukhet Aykin-Burns; Michael J Hitchler; Susan A Walsh; Frederick E Domann; Douglas R Spitz
Inhibition of glutamate cysteine ligase activity sensitizes human breast cancer cells to the toxicity of 2-deoxy-D-glucose.
Cancer research 2006;66(3):1605-10.
2005: Min Wang; Jeanie S Kirk; Sujatha Venkataraman; Frederick E Domann; Hannah J Zhang; Freya Q Schafer; Shawn W Flanagan; Christine J Weydert; Douglas R Spitz; Garry R Buettner; Larry W Oberley
Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1alpha and vascular endothelial growth factor.
Oncogene 2005;24(55):8154-66.
2005: Marc M Oshiro; Bernard W Futscher; Aaron Lisberg; Ryan Wozniak; Walter T Klimecki; Frederick E Domann; Anne E Cress
Epigenetic regulation of the cell type-specific gene 14-3-3sigma.
Neoplasia (New York, N.Y.) 2005;7(9):799-808.
2005: Angela M Devlin; Teodoro Bottiglieri; Frederick E Domann; Steven R Lentz
Tissue-specific changes in H19 methylation and expression in mice with hyperhomocysteinemia.
The Journal of biological chemistry 2005;280(27):25506-11.
2005: Gang Niu; Kimberly Krager; Michael M Graham; Richard D Hichwa; Frederick E Domann
Noninvasive radiological imaging of pulmonary gene transfer and expression using the human sodium iodide symporter.
European journal of nuclear medicine and molecular imaging 2005;32(5):534-40.
2005: Marc M Oshiro; Christina J Kim; Ryan Wozniak; Damian J Junk; José L Muñoz-Rodríguez; Jeanne A Burr; Matthew Fitzgerald; Sangita C Pawar; Anne E Cress; Frederick E Domann; Bernard W Futscher
Epigenetic silencing of DSC3 is a common event in human breast cancer.
Breast cancer research : BCR 2005;7(5):R669-80.
2004: Bernard W Futscher; Megan M O'Meara; Christina J Kim; Margaret A Rennels; Di Lu; Lynn M Gruman; Richard E B Seftor; Mary J C Hendrix; Frederick E Domann
Aberrant methylation of the maspin promoter is an early event in human breast cancer.
Neoplasia (New York, N.Y.) 2004;6(4):380-9.
2004: Frederick E Domann; Bernard W Futscher
Flipping the epigenetic switch.
The American journal of pathology 2004;164(6):1883-6.
2004: George S Watts; Marc M Oshiro; Damian J Junk; Ryan Wozniak; Summer Watterson; Frederick E Domann; Bernard W Futscher
The acetyltransferase p300/CBP-associated factor is a p53 target gene in breast tumor cells.
Neoplasia (New York, N.Y.) 2004;6(3):187-94.
2004: Gang Niu; Andrew W Gaut; Laura L Boles Ponto; Richard D Hichwa; Mark T Madsen; Michael M Graham; Frederick E Domann
Multimodality noninvasive imaging of gene transfer using the human sodium iodide symporter.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(3):445-9.
2004: Andrew W Gaut; Gang Niu; Kimberly Krager; Michael M Graham; Douglas K Trask; Frederick E Domann
Genetically targeted radiotherapy of head and neck squamous cell carcinoma using the sodium-iodide symporter (NIS).
Head & neck 2004;26(3):265-71.
2004: Anna C M Chaves; Karen Cherubini; Nilton Herter; Roque Furian; Diogenes S Santos; Christopher Squier; Frederick E Domann
Characterization of p53 gene mutations in a Brazilian population with oral squamous cell carcinomas.
International journal of oncology 2004;24(2):295-303.
2003: Joseph Nwankwo; Arthur A Spector; Frederick E Domann
A nucleotide insertion in the transcriptional regulatory region of FADS2 gives rise to human fatty acid delta-6-desaturase deficiency.
Journal of lipid research 2003;44(12):2311-9.
2003: Hong Duan; Hannah J Zhang; Ji-Qin Yang; Larry W Oberley; Bernard W Futscher; Frederick E Domann
MnSOD up-regulates maspin tumor suppressor gene expression in human breast and prostate cancer cells.
Antioxidants & redox signaling 2003;5(5):677-88.
2003: Lingjie Zhao; Hong P Wang; Hannah J Zhang; Christine J Weydert; Frederick E Domann; Larry W Oberley; Garry R Buettner
L-PhGPx expression can be suppressed by antisense oligodeoxynucleotides.
Archives of biochemistry and biophysics 2003;417(2):212-8.
2003: Matthew Fitzgerald; Marc M Oshiro; Nicholas Holtan; Kimberly Krager; Joseph J Cullen; Bernard W Futscher; Frederick E Domann
Human pancreatic carcinoma cells activate maspin expression through loss of epigenetic control.
Neoplasia (New York, N.Y.) 2003;5(5):427-36.
2003: Joseph J Cullen; Marilyn M Hinkhouse; Matthew Grady; Andrew W Gaut; Jingru Liu; Yu Ping Zhang; Christine J Weydert; Frederick E Domann; Larry W Oberley
Dicumarol inhibition of NADPH:quinone oxidoreductase induces growth inhibition of pancreatic cancer via a superoxide-mediated mechanism.
Cancer research 2003;63(17):5513-20.
2003: Tongrong He; Neal L Weintraub; Prabhat C Goswami; Papri Chatterjee; Dawn M Flaherty; Frederick E Domann; Larry W Oberley
Redox factor-1 contributes to the regulation of progression from G0/G1 to S by PDGF in vascular smooth muscle cells.
American journal of physiology. Heart and circulatory physiology 2003;285(2):H804-12.
2003: Marc M Oshiro; George S Watts; Ryan Wozniak; Damian J Junk; Jose L Munoz-Rodriguez; Frederick E Domann; Bernard W Futscher
Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression.
Oncogene 2003;22(23):3624-34.
2003: Joseph J Cullen; Christine Weydert; Marilyn M Hinkhouse; Justine Ritchie; Frederick E Domann; Douglas R Spitz; Larry W Oberley
The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma.
Cancer research 2003;63(6):1297-303.
2003: Frederick E Domann; Bernard W Futscher
Editorial: maspin as a molecular target for cancer therapy.
The Journal of urology 2003;169(3):1162-4.
2002: Geoffrey D Girnun; Frederick E Domann; Steven A Moore; Mike E Robbins
Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter.
Molecular endocrinology (Baltimore, Md.) 2002;16(12):2793-801.
2002: Bernard W Futscher; Marc M Oshiro; Ryan Wozniak; Nicholas Holtan; Christin L Hanigan; Hong Duan; Frederick E Domann
Role for DNA methylation in the control of cell type specific maspin expression.
Nature genetics 2002;31(2):175-9.
2002: Sherry R Timmons; Joseph Nwankwo; Frederick E Domann
Acetaldehyde activates Jun/AP-1 expression and DNA binding activity in human oral keratinocytes.
Oral oncology 2002;38(3):281-90.
2002: Ji-Qin Yang; Garry R Buettner; Frederick E Domann; Qiang Li; John F Engelhardt; Christine Weydert; Larry W Oberley
v-Ha-ras mitogenic signaling through superoxide and derived reactive oxygen species.
Molecular carcinogenesis 2002;33(4):206-18.
2002: Ying Zhang; Weiling Zhao; Hannah J Zhang; Frederick E Domann; Larry W Oberley
Overexpression of copper zinc superoxide dismutase suppresses human glioma cell growth.
Cancer research 2002;62(4):1205-12.
2002: Chun-Hong Zhu; Frederick E Domann
Dominant negative interference of transcription factor AP-2 causes inhibition of ErbB-3 expression and suppresses malignant cell growth.
Breast cancer research and treatment 2002;71(1):47-57.
2002: Hannah J Zhang; Victoria J Drake; Linjing Xu; Jianfang Hu; Frederick E Domann; Larry W Oberley; Kevin Kregel
Redox regulation of adenovirus-induced AP-1 activation by overexpression of manganese-containing superoxide dismutase.
Journal of virology 2002;76(1):355-63.
2001: J Q Yang; W Zhao; H Duan; Mike E Robbins; Garry R Buettner; Larry W Oberley; Frederick E Domann
v-Ha-RaS oncogene upregulates the 92-kDa type IV collagenase (MMP-9) gene by increasing cellular superoxide production and activating NF-kappaB.
Free radical biology & medicine 2001;31(4):520-9.
2001: Ji-Qin Yang; S Li; Y Huang; Hannah J Zhang; Frederick E Domann; Garry R Buettner; Larry W Oberley
V-Ha-Ras overexpression induces superoxide production and alters levels of primary antioxidant enzymes.
Antioxidants & redox signaling 2001;3(4):697-709.
2001: C Zhu; Y Huang; Christine J Weydert; Larry W Oberley; Frederick E Domann
Constitutive activation of transcription factor AP-2 is associated with decreased MnSOD expression in transformed human lung fibroblasts.
Antioxidants & redox signaling 2001;3(3):387-95.
2001: Chun-Hong Zhu; Y Huang; M T Broman; Frederick E Domann
Expression of AP-2 alpha in SV40 immortalized human lung fibroblasts is associated with a distinct pattern of cytosine methylation in the AP-2 alpha promoter.
Biochimica et biophysica acta 2001;1519(1-2):85-91.
2001: Chun-Hong Zhu; Y Huang; Larry W Oberley; Frederick E Domann
A family of AP-2 proteins down-regulate manganese superoxide dismutase expression.
The Journal of biological chemistry 2001;276(17):14407-13.
2001: Hong P Wang; Yue Qian; Freya Q Schafer; Frederick E Domann; Larry W Oberley; Garry R Buettner
Phospholipid hydroperoxide glutathione peroxidase protects against singlet oxygen-induced cell damage of photodynamic therapy.
Free radical biology & medicine 2001;30(8):825-35.
2000: Frederick E Domann; JC Rice; Mary J C Hendrix; Bernard W Futscher
Epigenetic silencing of maspin gene expression in human breast cancers.
International journal of cancer. Journal international du cancer 2000;85(6):805-10.
1999: Ji-Qin Yang; S Li; Frederick E Domann; Garry R Buettner; Larry W Oberley
Superoxide generation in v-Ha-ras-transduced human keratinocyte HaCaT cells.
Molecular carcinogenesis 1999;26(3):180-8.
1999: D T Cody; Y Huang; C J Darby; Georgia K Johnson; Frederick E Domann
Differential DNA methylation of the p16 INK4A/CDKN2A promoter in human oral cancer cells and normal human oral keratinocytes.
Oral oncology 1999;35(5):516-22.
1999: Y Huang; T He; Frederick E Domann
Decreased expression of manganese superoxide dismutase in transformed cells is associated with increased cytosine methylation of the SOD2 gene.
DNA and cell biology 1999;18(8):643-52.
1999: Y Huang; Frederick E Domann
Transcription factor AP-2 mRNA and DNA binding activity are constitutively expressed in SV40-immortalized but not normal human lung fibroblasts.
Archives of biochemistry and biophysics 1999;364(2):241-6.
1998: Y Huang; Frederick E Domann
Redox modulation of AP-2 DNA binding activity in vitro.
Biochemical and biophysical research communications 1998;249(2):307-12.
1997: E W Lam; Ralf Michael Zwacka; J F Engelhardt; B L Davidson; Frederick E Domann; T Yan; Larry W Oberley
Adenovirus-mediated manganese superoxide dismutase gene transfer to hamster cheek pouch carcinoma cells.
Cancer research 1997;57(24):5550-6.
1997: Eric E Kelley; Frederick E Domann; Garry R Buettner; Larry W Oberley; C Patrick Burns
Increased efficacy of in vitro Photofrin photosensitization of human oral squamous cell carcinoma by iron and ascorbate.
Journal of photochemistry and photobiology. B, Biology 1997;40(3):273-7.
1997: Y Huang; J Peng; Larry W Oberley; Frederick E Domann
Transcriptional inhibition of manganese superoxide dismutase (SOD2) gene expression by DNA methylation of the 5' CpG island.
Free radical biology & medicine 1997;23(2):314-20.
1997: J Peng; George Bowden; Frederick E Domann
Activation of AP-1 by okadaic acid in mouse keratinocytes associated with hyperphosphorylation of c-jun.
Molecular carcinogenesis 1997;18(1):37-43.
1996: W Zhong; Larry W Oberley; T D Oberley; T Yan; Frederick E Domann; D K St Clair
Inhibition of cell growth and sensitization to oxidative damage by overexpression of manganese superoxide dismutase in rat glioma cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(9):1175-86.
1995: Jian Jian Li; Frederick E Domann; Larry W Oberley
The use of RT-PCR to distinguish between plasmid MnSOD transcripts and endogenous MnSOD mRNA.
Biochemical and biophysical research communications 1995;216(2):610-8.