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Paul Domanski

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Anna Usacheva; Raudel Sandoval; Paul Domanski; Sergei V Kotenko; Keats Nelms; Mark A Goldsmith; Oscar R Colamonici
Contribution of the Box 1 and Box 2 motifs of cytokine receptors to Jak1 association and activation.
Owen W Nadeau; Paul Domanski; Anna Usacheva; Shahab Uddin; Leonidas C Platanias; PAULA PITHA-ROWE; R Raz; D Levy; Beata Majchrzak; Eleanor N Fish; Oscar R Colamonici
The proximal tyrosines of the cytoplasmic domain of the beta chain of the type I interferon receptor are essential for signal transducer and activator of transcription (Stat) 2 activation. Evidence that two Stat2 sites are required to reach a threshold of interferon alpha-induced Stat2 tyrosine phosphorylation that allows normal formation of interferon-stimulated gene factor 3.
Leonidas C Platanias; Paul Domanski; Owen W Nadeau; T Yi; Shahab Uddin; Eleanor N Fish; B G Neel; Oscar R Colamonici
Identification of a domain in the beta subunit of the type I interferon (IFN) receptor that exhibits a negative regulatory effect in the growth inhibitory action of type I IFNs.

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All Publications

2002: Anna Usacheva; Raudel Sandoval; Paul Domanski; Sergei V Kotenko; Keats Nelms; Mark A Goldsmith; Oscar R Colamonici
Contribution of the Box 1 and Box 2 motifs of cytokine receptors to Jak1 association and activation.
The Journal of biological chemistry 2002;277(50):48220-6.
1999: Owen W Nadeau; Paul Domanski; Anna Usacheva; Shahab Uddin; Leonidas C Platanias; PAULA PITHA-ROWE; R Raz; D Levy; Beata Majchrzak; Eleanor N Fish; Oscar R Colamonici
The proximal tyrosines of the cytoplasmic domain of the beta chain of the type I interferon receptor are essential for signal transducer and activator of transcription (Stat) 2 activation. Evidence that two Stat2 sites are required to reach a threshold of interferon alpha-induced Stat2 tyrosine phosphorylation that allows normal formation of interferon-stimulated gene factor 3.
The Journal of biological chemistry 1999;274(7):4045-52.
1998: Leonidas C Platanias; Paul Domanski; Owen W Nadeau; T Yi; Shahab Uddin; Eleanor N Fish; B G Neel; Oscar R Colamonici
Identification of a domain in the beta subunit of the type I interferon (IFN) receptor that exhibits a negative regulatory effect in the growth inhibitory action of type I IFNs.
The Journal of biological chemistry 1998;273(10):5577-81.
1998: Paul Domanski; Owen W Nadeau; Leonidas C Platanias; Eleanor N Fish; Merrill J Kellum; PAULA PITHA-ROWE; Oscar R Colamonici
Differential use of the betaL subunit of the type I interferon (IFN) receptor determines signaling specificity for IFNalpha2 and IFNbeta.
The Journal of biological chemistry 1998;273(6):3144-7.
1997: Paul Domanski; Eleanor N Fish; Owen W Nadeau; M Witte; Leonidas C Platanias; H Yan; J Krolewski; PAULA PITHA-ROWE; Oscar R Colamonici
A region of the beta subunit of the interferon alpha receptor different from box 1 interacts with Jak1 and is sufficient to activate the Jak-Stat pathway and induce an antiviral state.
The Journal of biological chemistry 1997;272(42):26388-93.
1996: Leonidas C Platanias; Shahab Uddin; Paul Domanski; Oscar R Colamonici
Differences in interferon alpha and beta signaling. Interferon beta selectively induces the interaction of the alpha and betaL subunits of the type I interferon receptor.
The Journal of biological chemistry 1996;271(39):23630-3.
1996: Paul Domanski; Oscar R Colamonici
The type-I interferon receptor. The long and short of it.
Cytokine & growth factor reviews 1996;7(2):143-51.
1995: Paul Domanski; H Yan; M M Witte; John Krolewski; Oscar R Colamonici
Homodimerization and intermolecular tyrosine phosphorylation of the Tyk-2 tyrosine kinase.
FEBS letters 1995;374(3):317-22.
1995: Paul Domanski; M Witte; Merrill J Kellum; M Rubinstein; R Hackett; PAULA PITHA-ROWE; Oscar R Colamonici
Cloning and expression of a long form of the beta subunit of the interferon alpha beta receptor that is required for signaling.
The Journal of biological chemistry 1995;270(37):21606-11.
1995: Oscar R Colamonici; Paul Domanski; Sharon Sweitzer; A Larner; R M Buller
Vaccinia virus B18R gene encodes a type I interferon-binding protein that blocks interferon alpha transmembrane signaling.
The Journal of biological chemistry 1995;270(27):15974-8.
1995: Oscar R Colamonici; Leonidas C Platanias; Paul Domanski; R Handa; K C Gilmour; Manuel O Diaz; N Reich; PAULA PITHA-ROWE
Transmembrane signaling by the alpha subunit of the type I interferon receptor is essential for activation of the JAK kinases and the transcriptional factor ISGF3.
The Journal of biological chemistry 1995;270(14):8188-93.
1994: Oscar R Colamonici; H Yan; Paul Domanski; R Handa; D Smalley; J Mullersman; M Witte; K Krishnan; John Krolewski
Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase.
Molecular and cellular biology 1994;14(12):8133-42.
1994: Oscar R Colamonici; B Porterfield; Paul Domanski; R K Handa; S Flex; C E Samuel; R Pine; Manuel O Diaz
Ligand-independent anti-oncogenic activity of the alpha subunit of the type I interferon receptor.
The Journal of biological chemistry 1994;269(44):27275-9.
1994: Oscar R Colamonici; B Porterfield; Paul Domanski; S Constantinescu; Lawrence M Pfeffer
Complementation of the interferon alpha response in resistant cells by expression of the cloned subunit of the interferon alpha receptor. A central role of this subunit in interferon alpha signaling.
The Journal of biological chemistry 1994;269(13):9598-602.
1994: Oscar R Colamonici; Paul Domanski; John Krolewski; X Y Fu; N C Reich; Lawrence M Pfeffer; M E Sweet; Leonidas C Platanias
Interferon alpha (IFN alpha) signaling in cells expressing the variant form of the type I IFN receptor.
The Journal of biological chemistry 1994;269(8):5660-5.
1994: Oscar R Colamonici; H Uyttendaele; Paul Domanski; H Yan; John Krolewski
p135tyk2, an interferon-alpha-activated tyrosine kinase, is physically associated with an interferon-alpha receptor.
The Journal of biological chemistry 1994;269(5):3518-22.
1993: Oscar R Colamonici; Paul Domanski
Identification of a novel subunit of the type I interferon receptor localized to human chromosome 21.
The Journal of biological chemistry 1993;268(15):10895-9.
1992: Oscar R Colamonici; Paul Domanski; Leonidas C Platanias; Manuel O Diaz
Correlation between interferon (IFN) alpha resistance and deletion of the IFN alpha/beta genes in acute leukemia cell lines suggests selection against the IFN system.
Blood 1992;80(3):744-9.