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Ana Lucia Dominguez

Research Profile

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Publications

TOP 3
Shannon E Smith; Jacques Van Snick; Ana Lucia Dominguez; Dominique Hoelzinger; Joseph Lustgarten
Signals through 4-1BB inhibit T regulatory cells by blocking IL-9 production enhancing antitumor responses.
Noweeda Mirza; Kevin Pollock; Ana Lucia Dominguez; Dominique Hoelzinger; Joseph Lustgarten
Comparative kinetic analyses of gene profiles of naïve CD4+ and CD8+ T cells from young and old animals reveal novel age-related alterations.
Soraya Zorro Manrique; Noweeda Mirza; Joan Stein-Streilein; Maria Adelaida Duque Correa; Ana Lucia Dominguez; Siamon Gordon; Dominique Hoelzinger; Hsi-Hsien Lin; Joseph Lustgarten
Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth.

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All Publications

2011: Shannon E Smith; Jacques Van Snick; Ana Lucia Dominguez; Dominique Hoelzinger; Joseph Lustgarten
Signals through 4-1BB inhibit T regulatory cells by blocking IL-9 production enhancing antitumor responses.
Cancer immunology, immunotherapy : CII 2011;60(12):1775-87.
2011: Noweeda Mirza; Kevin Pollock; Ana Lucia Dominguez; Dominique Hoelzinger; Joseph Lustgarten
Comparative kinetic analyses of gene profiles of naïve CD4+ and CD8+ T cells from young and old animals reveal novel age-related alterations.
Aging cell 2011;10(5):853-67.
2011: Soraya Zorro Manrique; Noweeda Mirza; Joan Stein-Streilein; Maria Adelaida Duque Correa; Ana Lucia Dominguez; Siamon Gordon; Dominique Hoelzinger; Hsi-Hsien Lin; Joseph Lustgarten
Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth.
The Journal of experimental medicine 2011;208(7):1485-99.
2010: Dominique B Hoelzinger; Shannon E Smith; Noweeda Mirza; Ana Lucia Dominguez; Soraya Zorro Manrique; Joseph Lustgarten
Blockade of CCL1 inhibits T regulatory cell suppressive function enhancing tumor immunity without affecting T effector responses.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(12):6833-42.
2010: Noweeda Mirza; Maria Adelaida Duque; Ana Lucia Dominguez; Adam G Schrum; Haidong Dong; Joseph Lustgarten
B7-H1 expression on old CD8+ T cells negatively regulates the activation of immune responses in aged animals.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(10):5466-74.
2010: Ana Lucia Dominguez; Joseph Lustgarten
Targeting the tumor microenvironment with anti-neu/anti-CD40 conjugated nanoparticles for the induction of antitumor immune responses.
Vaccine 2010;28(5):1383-90.
2008: Sanjay Sharma; Ana Lucia Dominguez; Soraya Zorro Manrique; Federica Cavallo; Shimon Sakaguchi; Joseph Lustgarten
Systemic targeting of CpG-ODN to the tumor microenvironment with anti-neu-CpG hybrid molecule and T regulatory cell depletion induces memory responses in BALB-neuT tolerant mice.
Cancer research 2008;68(18):7530-40.
2008: Ana Lucia Dominguez; Joseph Lustgarten
Implications of aging and self-tolerance on the generation of immune and antitumor immune responses.
Cancer research 2008;68(13):5423-31.
2008: Sanjay Sharma; Ana Lucia Dominguez; Dominique Hoelzinger; Joseph Lustgarten
CpG-ODN but not other TLR-ligands restore the antitumor responses in old mice: the implications for vaccinations in the aged.
Cancer immunology, immunotherapy : CII 2008;57(4):549-61.
2006: Sanjay Sharma; Ana Lucia Dominguez; Joseph Lustgarten
High accumulation of T regulatory cells prevents the activation of immune responses in aged animals.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(12):8348-55.
2006: Joseph Lustgarten; Ana Lucia Dominguez; Clemencia Pinilla
Identification of cross-reactive peptides using combinatorial libraries circumvents tolerance against Her-2/neu-immunodominant epitope.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(3):1796-805.
2006: Sanjay Sharma; Ana Lucia Dominguez; Joseph Lustgarten
Aging affect the anti-tumor potential of dendritic cell vaccination, but it can be overcome by co-stimulation with anti-OX40 or anti-4-1BB.
Experimental gerontology 2006;41(1):78-84.
2005: Camilo Cuadros; Ana Lucia Dominguez; Pier-Luigi Lollini; Michael Croft; Robert S Mittler; Per Borgström; Joseph Lustgarten
Vaccination with dendritic cells pulsed with apoptotic tumors in combination with anti-OX40 and anti-4-1BB monoclonal antibodies induces T cell-mediated protective immunity in Her-2/neu transgenic mice.
International journal of cancer. Journal international du cancer 2005;116(6):934-43.
2004: Joseph Lustgarten; Ana Lucia Dominguez; Marilyn L Thoman
Aged mice develop protective antitumor immune responses with appropriate costimulation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(7):4510-5.
2004: Camilo Cuadros; Francisco J Lopez-Hernandez; Ana Lucia Dominguez; Michael McClelland; Joseph Lustgarten
Flagellin fusion proteins as adjuvants or vaccines induce specific immune responses.
Infection and immunity 2004;72(5):2810-6.
2004: Joseph Lustgarten; Ana Lucia Dominguez; Camilo Cuadros
The CD8+ T cell repertoire against Her-2/neu antigens in neu transgenic mice is of low avidity with antitumor activity.
European journal of immunology 2004;34(3):752-61.
2003: Camilo Cuadros; Ana Lucia Dominguez; Gregory I Frost; Per Borgstrom; Joseph Lustgarten
Cooperative effect between immunotherapy and antiangiogenic therapy leads to effective tumor rejection in tolerant Her-2/neu mice.
Cancer research 2003;63(18):5895-901.