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Ole Ammerpohl

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Physiology

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Oligonucleotide Array Sequence Analysis

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Birte Malaika Overbeck; Reiner Siebert; Ole Ammerpohl; Wolfram Klapper; Jose I Martin-Subero; Maciej Giefing
ETS1 encoding a transcription factor involved in B-cell differentiation is recurrently deleted and down-regulated in classical Hodgkin's lymphoma.
Atosa Esteki-Zadeh; Maja Jagodic; Mohsen Karimi; Marjan Mehrab-Mohseni; Afsar Rahbar; Louise Sjöholm; Cecilia Söderberg-Nauclér; Klas Strååt; Manuel Zeitelhofer; Ole Ammerpohl; Tomas J Ekström
Human cytomegalovirus infection is sensitive to the host cell DNA methylation state and alters global DNA methylation capacity.
Julia Richter; Steffen Paschen; Ole Ammerpohl; Silke Appenzeller; Norbert Brüggemann; Günther Deuschl; Christine Klein; Gregor Kuhlenbäumer
No evidence for differential methylation of α-synuclein in leukocyte DNA of Parkinson's disease patients.

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All Publications

2012: Birte Malaika Overbeck; Reiner Siebert; Ole Ammerpohl; Wolfram Klapper; Jose I Martin-Subero; Maciej Giefing
ETS1 encoding a transcription factor involved in B-cell differentiation is recurrently deleted and down-regulated in classical Hodgkin's lymphoma.
Haematologica 2012;97(10):1612-4.
2012: Atosa Esteki-Zadeh; Maja Jagodic; Mohsen Karimi; Marjan Mehrab-Mohseni; Afsar Rahbar; Louise Sjöholm; Cecilia Söderberg-Nauclér; Klas Strååt; Manuel Zeitelhofer; Ole Ammerpohl; Tomas J Ekström
Human cytomegalovirus infection is sensitive to the host cell DNA methylation state and alters global DNA methylation capacity.
Epigenetics : official journal of the DNA Methylation Society 2012;7(6):585-93.
2012: Julia Richter; Steffen Paschen; Ole Ammerpohl; Silke Appenzeller; Norbert Brüggemann; Günther Deuschl; Christine Klein; Gregor Kuhlenbäumer
No evidence for differential methylation of α-synuclein in leukocyte DNA of Parkinson's disease patients.
Movement disorders : official journal of the Movement Disorder Society 2012;27(4):590-1.
2012: Ole Ammerpohl; Alexander Arlt; Katharina Balschun; Thomas Becker; Mario Brosch; Wladimir Faber; Jonas Grauholm; Andrea Haake; Holger Kalthoff; Peter Neuhaus; Johann Pratschke; Christoph Röcken; Clemens Schafmayer; Bodo Schniewind; Stefan Schreiber; Reiner Siebert; Bence Sipos; Felix Stickel; Oliver von Kampen; Witigo von Schönfels; Jochen Hampe
Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma.
International journal of cancer. Journal international du cancer 2012;130(6):1319-28.
2012: Christel Eckmann-Scholz; Simone Heidemann; Walter Jonat; Monika Kautza; Julia Kolarova; Sina Schneppenheim; Reiner Siebert; Constantin von Kaisenberg; Susanne Bens; Almuth Caliebe; Ole Ammerpohl
DNA-methylation profiling of fetal tissues reveals marked epigenetic differences between chorionic and amniotic samples.
PloS one 2012;7(6):e39014.
2012: Jessica Roessler; Ole Ammerpohl; Sumadi Lukman Anwar; Jana Gutwein; Britta Hasemeier; Hans Kreipe; Ulrich Lehmann
Quantitative cross-validation and content analysis of the 450k DNA methylation array from Illumina, Inc.
BMC research notes 2012;5():210.
2011: Idoia Martín-Guerrero; Julia Richter; Antonio Salas; Reiner Siebert; Ole Ammerpohl; Maite Ardanaz; Elias Campo; Dolors Colomer; Anna Enjuanes; Fernando Marco; A García-Orad
A putative "hepitype" in the ATM gene associated with chronic lymphocytic leukemia risk.
Genes, chromosomes & cancer 2011;50(11):887-95.
2011: Corinna von Forstner; Maaz Zuhayra; Ole Ammerpohl; Yi Zhao; Sanjay Tiwari; Olav Jansen; Holger Kalthoff; Eberhard Henze; Jan-Hendrik Egberts
Expression of L amino acid transport system 1 and analysis of iodine-123-methyltyrosine tumor uptake in a pancreatic xenotransplantation model using fused high-resolution-micro-SPECT-MRI.
Hepatobiliary & pancreatic diseases international : HBPD INT 2011;10(1):30-7.
2011: Alexander Herrmann; Steve K Kotsopoulos; Michael Krawczak; Darren R Link; Idoia Martin-Guerrero; Michael Nothnagel; Peter Nürnberg; Jeff Olson; Matthias Platzer; Julia Richter; Stefan Schreiber; Reiner Siebert; Kathryn Stemshorn; Karol Szafranski; Jason Warner; Ole Ammerpohl; Andrea Haake; Jochen Hampe
Pipeline for large-scale microdroplet bisulfite PCR-based sequencing allows the tracking of hepitype evolution in tumors.
PloS one 2011;6(7):e21332.
2011: Dirk Bauerschlag; Karen Bräutigam; Felix Hilpert; Qiong Lin; Nicolai Maass; Ivo Meinhold-Heerlein; Christian Schem; Ole Ammerpohl; Norbert Arnold; Marion T Weigel; Wolfgang Wagner
Progression-free survival in ovarian cancer is reflected in epigenetic DNA methylation profiles.
Oncology 2011;80(1-2):12-20.
2010: Inga Nagel; Monika Szczepanowski; José I Martín-Subero; Lana Harder; Takashi Akasaka; Ole Ammerpohl; Evelyne Callet-Bauchu; Randy D Gascoyne; Stefan Gesk; Doug Horsman; Wolfram Klapper; Aneela Majid; Jose A Martinez-Climent; Stephan Stilgenbauer; Holger Tönnies; Martin J S Dyer; Reiner Siebert
Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies.
Blood 2010;116(8):1317-20.
2010: Hendrik Wermann; hans stoop; Ad J M Gillis; Friedemann Honecker; Ruud van Gurp; Ole Ammerpohl; Julia Richter; J Wolter Oosterhuis; Carsten Bokemeyer; Leendert H J Looijenga
Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance.
The Journal of pathology 2010;221(4):433-42.
2010: Felix Rückert; Gihan Dawelbait; Christof Winter; Arndt Hartmann; Axel Denz; Ole Ammerpohl; Michael Schroeder; Hans Konrad Schackert; Bence Sipos; Günter Klöppel; Holger Kalthoff; Hans-Detlev Saeger; Christian Pilarsky; Robert Grützmann
Examination of apoptosis signaling in pancreatic cancer by computational signal transduction analysis.
PloS one 2010;5(8):e12243.
2010: Ole Ammerpohl; Sanjay Tiwari; Holger Kalthoff
Target gene discovery for novel therapeutic agents in cancer treatment.
Methods in molecular biology (Clifton, N.J.) 2010;576():427-45.
2009: Deniz Kanber; Tea Berulava; Ole Ammerpohl; Diana Mitter; Julia Richter; Reiner Siebert; Bernhard Horsthemke; Dietmar Lohmann; Karin Buiting
The human retinoblastoma gene is imprinted.
PLoS genetics 2009;5(12):e1000790.
2009: I Nagel; S Bug; H Tönnies; Ole Ammerpohl; J Richter; I Vater; E Callet-Bauchu; M J Calasanz; Jose A Martinez-Climent; C Bastard; M Salido; E Schroers; J I Martin-Subero; Stefan Gesk; Lana Harder; A Majid; M J S Dyer; R Siebert
Biallelic inactivation of TRAF3 in a subset of B-cell lymphomas with interstitial del(14)(q24.1q32.33).
Leukemia 2009;23(11):2153-5.
2009: Heinrich Schwindt; I Vater; M Kreuz; Manuel Montesinos-Rongen; Anna Brunn; J Richter; Stefan Gesk; Ole Ammerpohl; Otmar D Wiestler; Dirk Hasenclever; Martina Deckert; Reiner Siebert
Chromosomal imbalances and partial uniparental disomies in primary central nervous system lymphoma.
Leukemia 2009;23(10):1875-84.
2009: Ole Ammerpohl; José I Martín-Subero; Julia Richter; Inga Vater; Reiner Siebert
Hunting for the 5th base: Techniques for analyzing DNA methylation.
Biochimica et biophysica acta 2009;1790(9):847-62.
2009: Julia Richter; Ole Ammerpohl; José I Martín-Subero; Manuel Montesinos-Rongen; Marina Bibikova; Eliza Wickham-Garcia; Otmar D Wiestler; Martina Deckert; Reiner Siebert
Array-based DNA methylation profiling of primary lymphomas of the central nervous system.
BMC cancer 2009;9():455.
2008: Christian Pilarsky; Ole Ammerpohl; Bence Sipos; Edgar Dahl; Arndt Hartmann; Axel Wellmann; Till Braunschweig; Matthias Löhr; Ralf Jesnowski; Helmut Friess; Moritz Wente; Glen Kristiansen; Beatrix Jahnke; Axel Denz; Felix Rückert; Hans K Schackert; Günter Klöppel; Holger Kalthoff; Hans-Detlev Saeger; Ralf Jesenofsky; Robert Grützmann
Activation of Wnt signalling in stroma from pancreatic cancer identified by gene expression profiling.
Journal of cellular and molecular medicine 2008;12(6B):2823-35.
2008: Susanne Sebens Müerköster; Veronika Werbing; Dorothee Koch; Bence Sipos; Ole Ammerpohl; Holger Kalthoff; Ming Tsao; Ulrich R Fölsch; Heiner Schäfer
Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases.
International journal of cancer. Journal international du cancer 2008;123(8):1751-60.
2008: Corinna von Forstner; Jan-Hendrik Egberts; Ole Ammerpohl; Dagmara Niedzielska; Ralph Buchert; Pal Mikecz; Udo Schumacher; Kersten Peldschus; Gerhard Adam; Christian Pilarsky; Robert Grutzmann; Holger Kalthoff; Eberhard Henze; Winfried Brenner
Gene expression patterns and tumor uptake of 18F-FDG, 18F-FLT, and 18F-FEC in PET/MRI of an orthotopic mouse xenotransplantation model of pancreatic cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(8):1362-70.
2007: Sebastian Hinz; Laia Pagerols-Raluy; Hans-Heinrich Oberg; Ole Ammerpohl; Sandra Grüssel; Bence Sipos; Robert Grützmann; Christian Pilarsky; Hendrik Ungefroren; Hans-Detlev Saeger; Günter Klöppel; Dieter Kabelitz; Holger Kalthoff
Foxp3 expression in pancreatic carcinoma cells as a novel mechanism of immune evasion in cancer.
Cancer research 2007;67(17):8344-50.
2007: Ole Ammerpohl; Holger Kalthoff
The role of protein kinases in pancreatic carcinogenesis.
Clinica chimica acta; international journal of clinical chemistry 2007;381(1):56-62.
2007: Irina Svechnikova; Ole Ammerpohl; Tomas J Ekström
p21waf1/Cip1 partially mediates apoptosis in hepatocellular carcinoma cells.
Biochemical and biophysical research communications 2007;354(2):466-71.
2007: Monika Olempska; Patricia Alice Eisenach; Ole Ammerpohl; Hendrik Ungefroren; Fred Fandrich; Holger Kalthoff
Detection of tumor stem cell markers in pancreatic carcinoma cell lines.
Hepatobiliary & pancreatic diseases international : HBPD INT 2007;6(1):92-7.
2007: Ole Ammerpohl; Anna Trauzold; Bodo Schniewind; U Griep; Christian Pilarsky; R Grutzmann; Hans-Detlev Saeger; Ottmar Janssen; Bence Sipos; G Kloppel; Holger Kalthoff
Complementary effects of HDAC inhibitor 4-PB on gap junction communication and cellular export mechanisms support restoration of chemosensitivity of PDAC cells.
British journal of cancer 2007;96(1):73-81.
2006: Bodo Schniewind; Kirsten Heintz; Roland Kurdow; Ole Ammerpohl; Anna Trauzold; Doris Emme; Peter Dohrmann; Holger Kalthoff
Combination phenylbutyrate/gemcitabine therapy effectively inhibits in vitro and in vivo growth of NSCLC by intrinsic apoptotic pathways.
Journal of carcinogenesis 2006;5():25.
2005: Robert Grützmann; Hinnerk Boriss; Ole Ammerpohl; Jutta Lüttges; Holger Kalthoff; Hans K Schackert; Günter Klöppel; Hans-Detlev Saeger; Christian Pilarsky
Meta-analysis of microarray data on pancreatic cancer defines a set of commonly dysregulated genes.
Oncogene 2005;24(32):5079-88.
2004: Ole Ammerpohl; Dorit Thormeyer; Zahidul Khan; Ioulia B Appelskog; Zoran Gojkovic; Per M Almqvist; Tomas J Ekström
HDACi phenylbutyrate increases bystander killing of HSV-tk transfected glioma cells.
Biochemical and biophysical research communications 2004;324(1):8-14.
2004: Robert Grützmann; Christian Pilarsky; Ole Ammerpohl; Jutta Lüttges; Armin Böhme; Bence Sipos; Melanie Foerder; Ingo Alldinger; Beatrix Jahnke; Hans K Schackert; Holger Kalthoff; Bernd Kremer; Günter Klöppel; Hans-Detlev Saeger
Gene expression profiling of microdissected pancreatic ductal carcinomas using high-density DNA microarrays.
Neoplasia (New York, N.Y.) 2004;6(5):611-22.
2004: Ioulia B Appelskog; Ole Ammerpohl; Irina Svechnikova; W-O Lui; Per M Almqvist; Tomas J Ekström
Histone deacetylase inhibitor 4-phenylbutyrate suppresses GAPDH mRNA expression in glioma cells.
International journal of oncology 2004;24(6):1419-25.
2004: Thomas Asklund; Ioulia B Appelskog; Ole Ammerpohl; Tomas J Ekström; Per M Almqvist
Histone deacetylase inhibitor 4-phenylbutyrate modulates glial fibrillary acidic protein and connexin 43 expression, and enhances gap-junction communication, in human glioblastoma cells.
European journal of cancer (Oxford, England : 1990) 2004;40(7):1073-81.
2004: Robert Grützmann; Jutta Lüttges; Bence Sipos; Ole Ammerpohl; Frank Dobrowolski; Ingo Alldinger; Stephan Kersting; Detlef Ockert; R Koch; Holger Kalthoff; Hans K Schackert; Hans-Detlev Saeger; Günter Klöppel; Christian Pilarsky
ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma.
British journal of cancer 2004;90(5):1053-8.
2003: Thomas Asklund; Ioulia B Appelskog; Ole Ammerpohl; Iver A Langmoen; M Sirac Dilber; Alar Aints; Tomas J Ekström; Per M Almqvist
Gap junction-mediated bystander effect in primary cultures of human malignant gliomas with recombinant expression of the HSVtk gene.
Experimental cell research 2003;284(2):185-95.
2003: Dorit Thormeyer; Ole Ammerpohl; Ola Larsson; Y Xu; A Asinger; Claes Wahlestedt; Z Liang
Characterization of lacZ complementation deletions using membrane receptor dimerization.
BioTechniques 2003;34(2):346-50, 352-5.