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Robert Doms

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Chemicals & Drugs

Anatomy

Cell Line

Physiology

Membrane Fusion

Disorders

HIV Infections

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

Procedures

Neutralization Tests

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Co-Publications
Name
24
Lee, Virginia M-Y
23
Doranz, Benjamin
23
Pöhlmann, Stefan
23
Lee, Benhur
22
Baribaud, Frédéric
20
Hoxie, James
20
Sharron, Matthew
17
Rucker, J
16
Pierson, Theodore
15
Hoffman, Trevor
14
Leslie, George
13
Parmentier, Marc
12
Puffer, Bridget
12
Edinger, Aimee
11
Reeves, Jacqueline

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Publications

TOP 3
Agrawal-Gamse Caroline; Lee Fang-Hua; Haggarty Beth; Jordan Andrea P O; Yi Yanjie; Lee Benhur; Collman Ronald G; Hoxie James A; Doms Robert W; Laakso Meg M
Adaptive mutations in a human immunodeficiency virus type 1 envelope protein with a truncated V3 loop restore function by improving interactions with CD4.
Pugach Pavel; Ray Neelanjana; Klasse Per Johan; Ketas Thomas J; Michael Elizabeth; Doms Robert W; Lee Benhur; Moore John P
Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities.
Luallen Robert J; Fu Hu; Agrawal-Gamse Caroline; Mboudjeka Innocent; Huang Wei; Lee Fang-Hua; Wang Lai-Xi; Doms Robert W; Geng Yu
A yeast glycoprotein shows high-affinity binding to the broadly neutralizing human immunodeficiency virus antibody 2G12 and inhibits gp120 interactions with 2G12 and DC-SIGN.

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All Publications

2009: Agrawal-Gamse Caroline; Lee Fang-Hua; Haggarty Beth; Jordan Andrea P O; Yi Yanjie; Lee Benhur; Collman Ronald G; Hoxie James A; Doms Robert W; Laakso Meg M
Adaptive mutations in a human immunodeficiency virus type 1 envelope protein with a truncated V3 loop restore function by improving interactions with CD4.
Journal of virology 2009;83(21):11005-15.
2009: Pugach Pavel; Ray Neelanjana; Klasse Per Johan; Ketas Thomas J; Michael Elizabeth; Doms Robert W; Lee Benhur; Moore John P
Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities.
Virology 2009;387(2):296-302.
2009: Luallen Robert J; Fu Hu; Agrawal-Gamse Caroline; Mboudjeka Innocent; Huang Wei; Lee Fang-Hua; Wang Lai-Xi; Doms Robert W; Geng Yu
A yeast glycoprotein shows high-affinity binding to the broadly neutralizing human immunodeficiency virus antibody 2G12 and inhibits gp120 interactions with 2G12 and DC-SIGN.
Journal of virology 2009;83(10):4861-70.
2009: Wu Lan; Zhou Tongqing; Yang Zhi-yong; Svehla Krisha; O'Dell Sijy; Louder Mark K; Xu Ling; Mascola John R; Burton Dennis R; Hoxie James A; Doms Robert W; Kwong Peter D; Nabel Gary J
Enhanced exposure of the CD4-binding site to neutralizing antibodies by structural design of a membrane-anchored human immunodeficiency virus type 1 gp120 domain.
Journal of virology 2009;83(10):5077-86.
2009: Ray Neelanjana; Blackburn Leslie A; Doms Robert W
HR-2 mutations in human immunodeficiency virus type 1 gp41 restore fusion kinetics delayed by HR-1 mutations that cause clinical resistance to enfuvirtide.
Journal of virology 2009;83(7):2989-95.
2008: Harrison Jessamina E; Lynch Jonathan B; Sierra Luz-Jeannette; Blackburn Leslie A; Ray Neelanjana; Collman Ronald G; Doms Robert W
Baseline resistance of primary human immunodeficiency virus type 1 strains to the CXCR4 inhibitor AMD3100.
Journal of virology 2008;82(23):11695-704.
2008: Luallen Robert J; Lin Jianqiao; Fu Hu; Cai Karen K; Agrawal Caroline; Mboudjeka Innocent; Lee Fang-Hua; Montefiori David; Smith David F; Doms Robert W; Geng Yu
An engineered Saccharomyces cerevisiae strain binds the broadly neutralizing human immunodeficiency virus type 1 antibody 2G12 and elicits mannose-specific gp120-binding antibodies.
Journal of virology 2008;82(13):6447-57.
2008: Dey Antu K; David Kathryn B; Ray Neelanjana; Ketas Thomas J; Klasse Per J; Doms Robert W; Moore John P
N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus.
Virology 2008;372(1):187-200.
2008: Selvarajah Suganya; Puffer Bridget A; Lee Fang-Hua; Zhu Ping; Li Yuxing; Wyatt Richard; Roux Kenneth H; Doms Robert W; Burton Dennis R
Focused dampening of antibody response to the immunodominant variable loops by engineered soluble gp140.
AIDS research and human retroviruses 2008;24(2):301-14.
2007: Marzi Andrea; Mitchell Daniel A; Chaipan Chawaree; Fisch Tanja; Doms Robert W; Carrington Mary; Desrosiers Ronald C; Pöhlmann Stefan
Modulation of HIV and SIV neutralization sensitivity by DC-SIGN and mannose-binding lectin.
Virology 2007;368(2):322-30.
2007: Lin George; Bertolotti-Ciarlet Andrea; Haggarty Beth; Romano Josephine; Nolan Katrina M; Leslie George J; Jordan Andrea P-O; Huang Chih-chin; Kwong Peter D; Doms Robert W; Hoxie James A
Replication-competent variants of human immunodeficiency virus type 2 lacking the V3 loop exhibit resistance to chemokine receptor antagonists.
Journal of virology 2007;81(18):9956-66.
2007: Laakso Meg M; Lee Fang-Hua; Haggarty Beth; Agrawal Caroline; Nolan Katrina M; Biscone Mark; Romano Josephine; Jordan Andrea P O; Leslie George J; Meissner Eric G; Su Lishan; Hoxie James A; Doms Robert W
V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies.
PLoS pathogens 2007;3(8):e117.
2007: Dhillon Amandeep K; Donners Helen; Pantophlet Ralph; Johnson Welkin E; Decker Julie M; Shaw George M; Lee Fang-Hua; Richman Douglas D; Doms Robert W; Vanham Guido; Burton Dennis R
Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donors.
Journal of virology 2007;81(12):6548-62.
2007: Altamura Louis A; Bertolotti-Ciarlet Andrea; Teigler Jeffrey; Paragas Jason; Schmaljohn Connie S; Doms Robert W
Identification of a novel C-terminal cleavage of Crimean-Congo hemorrhagic fever virus PreGN that leads to generation of an NSM protein.
Journal of virology 2007;81(12):6632-42.
2007: Ray Neelanjana; Harrison Jessamina E; Blackburn Leslie A; Martin Jeffrey N; Deeks Steven G; Doms Robert W
Clinical resistance to enfuvirtide does not affect susceptibility of human immunodeficiency virus type 1 to other classes of entry inhibitors.
Journal of virology 2007;81(7):3240-50.
2007: Pöhlmann Stefan; Münch Jan; Aziz Sheriff; Reeves Jacqueline D; Otto Claas; Leslie George J; Hofmann Heike; Puffer Bridget A; Baribaud Frédéric; Marzi Andrea; Gramberg Thomas; Chen Zhiwei; Stolte Nicole; Haaft Peter Ten; Heeney Jonathan L; Stahl-Hennig Christiane; Mätz-Rensing Kerstin; Schneider Thomas; Doms Robert W; Kirchhoff Frank
A simian immunodeficiency virus V3 loop mutant that does not efficiently use CCR5 or common alternative coreceptors is moderately attenuated in vivo.
Virology 2007;360(2):275-85.
2007: Sánchez Melissa D; Pierson Theodore C; Degrace Marciela M; Mattei Lisa M; Hanna Sheri L; Del Piero Fabio; Doms Robert W
The neutralizing antibody response against West Nile virus in naturally infected horses.
Virology 2007;359(2):336-48.
2006: Davis Carl W; Mattei Lisa M; Nguyen Hai-Yen; Ansarah-Sobrinho Camilo; Doms Robert W; Pierson Theodore C
The location of asparagine-linked glycans on West Nile virions controls their interactions with CD209 (dendritic cell-specific ICAM-3 grabbing nonintegrin).
The Journal of biological chemistry 2006;281(48):37183-94.
2006: Filone Claire Marie; Heise Mark; Doms Robert W; Bertolotti-Ciarlet Andrea
Development and characterization of a Rift Valley fever virus cell-cell fusion assay using alphavirus replicon vectors.
Virology 2006;356(1-2):155-64.
2006: Morais Vanessa A; Brito Catarina; Pijak Donald S; Crystal Adam S; Fortna Ryan R; Li Tong; Wong Phil C; Doms Robert W; Costa Júlia
N-glycosylation of human nicastrin is required for interaction with the lectins from the secretory pathway calnexin and ERGIC-53.
Biochimica et biophysica acta 2006;1762(9):802-10.
2006: Biscone Mark J; Miamidian John L; Muchiri John M; Baik Sarah S W; Lee Fang-Hua; Doms Robert W; Reeves Jacqueline D
Functional impact of HIV coreceptor-binding site mutations.
Virology 2006;351(1):226-36.
2006: Pierson Theodore C; Sánchez Melissa D; Puffer Bridget A; Ahmed Asim A; Geiss Brian J; Valentine Laura E; Altamura Louis A; Diamond Michael S; Doms Robert W
A rapid and quantitative assay for measuring antibody-mediated neutralization of West Nile virus infection.
Virology 2006;346(1):53-65.
2006: Davis Carl W; Nguyen Hai-Yen; Hanna Sheri L; Sánchez Melissa D; Doms Robert W; Pierson Theodore C
West Nile virus discriminates between DC-SIGN and DC-SIGNR for cellular attachment and infection.
Journal of virology 2006;80(3):1290-301.
2006: Haskell Christopher A; Horuk Richard; Liang Meina; Rosser Mary; Dunning Laura; Islam Imadul; Kremer Leonor; Gutiérrez Julio; Marquez Gabriel; Martinez-A Carlos; Biscone Mark J; Doms Robert W; Ribeiro Sofia
Identification and characterization of a potent, selective nonpeptide agonist of the CC chemokine receptor CCR8.
Molecular pharmacology 2006;69(1):309-16.
2006: Gallo Stephen A; Reeves Jacqueline D; Garg Himanshu; Foley Brian; Doms Robert W; Blumenthal Robert
Kinetic studies of HIV-1 and HIV-2 envelope glycoprotein-mediated fusion.
Retrovirology 2006;3():90.
2006: Ray N; Doms R W
HIV-1 coreceptors and their inhibitors.
Current topics in microbiology and immunology 2006;303():97-120.
2005: Ahmed Asim A; McFalls Jeanne M; Hoffmann Christian; Filone Claire Marie; Stewart Shaun M; Paragas Jason; Khodjaev Shabot; Shermukhamedova Dilbar; Schmaljohn Connie S; Doms Robert W; Bertolotti-Ciarlet Andrea
Presence of broadly reactive and group-specific neutralizing epitopes on newly described isolates of Crimean-Congo hemorrhagic fever virus.
The Journal of general virology 2005;86(Pt 12):3327-36.
2005: Hanna Sheri L; Pierson Theodore C; Sanchez Melissa D; Ahmed Asim A; Murtadha Mariam M; Doms Robert W
N-linked glycosylation of west nile virus envelope proteins influences particle assembly and infectivity.
Journal of virology 2005;79(21):13262-74.
2005: Selvarajah Suganya; Puffer Bridget; Pantophlet Ralph; Law Mansun; Doms Robert W; Burton Dennis R
Comparing antigenicity and immunogenicity of engineered gp120.
Journal of virology 2005;79(19):12148-63.
2005: Whitby Kevin; Pierson Theodore C; Geiss Brian; Lane Kelly; Engle Michael; Zhou Yi; Doms Robert W; Diamond Michael S
Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivo.
Journal of virology 2005;79(14):8698-706.
2005: Sánchez Melissa D; Pierson Theodore C; McAllister Douglas; Hanna Sheri L; Puffer Bridget A; Valentine Laura E; Murtadha Mariam M; Hoxie James A; Doms Robert W
Characterization of neutralizing antibodies to West Nile virus.
Virology 2005;336(1):70-82.
2005: Bertolotti-Ciarlet Andrea; Smith Jonathan; Strecker Karin; Paragas Jason; Altamura Louis A; McFalls Jeanne M; Frias-Stäheli Natalia; García-Sastre Adolfo; Schmaljohn Connie S; Doms Robert W
Cellular localization and antigenic characterization of crimean-congo hemorrhagic fever virus glycoproteins.
Journal of virology 2005;79(10):6152-61.
2005: Reeves Jacqueline D; Lee Fang-Hua; Miamidian John L; Jabara Cassandra B; Juntilla Marisa M; Doms Robert W
Enfuvirtide resistance mutations: impact on human immunodeficiency virus envelope function, entry inhibitor sensitivity, and virus neutralization.
Journal of virology 2005;79(8):4991-9.
2005: Pierson Theodore C; Diamond Michael S; Ahmed Asim A; Valentine Laura E; Davis Carl W; Samuel Melanie A; Hanna Sheri L; Puffer Bridget A; Doms Robert W
An infectious West Nile virus that expresses a GFP reporter gene.
Virology 2005;334(1):28-40.
2005: Lee Edward B; Zhang Bin; Liu Kangning; Greenbaum Eric A; Doms Robert W; Trojanowski John Q; Lee Virginia M-Y
BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo.
The Journal of cell biology 2005;168(2):291-302.
2004: Doms Robert W
Unwelcome guests with master keys: how HIV enters cells and how it can be stopped.
Topics in HIV medicine : a publication of the International AIDS Society, USA 2004;12(4):100-3.
2004: Puffer Bridget A; Altamura Louis A; Pierson Theodore C; Doms Robert W
Determinants within gp120 and gp41 contribute to CD4 independence of SIV Envs.
Virology 2004;327(1):16-25.
2004: Doms Robert W
Viral entry denied.
The New England journal of medicine 2004;351(8):743-4.
2004: Pierson Theodore C; Doms Robert W; Pöhlmann Stefan
Prospects of HIV-1 entry inhibitors as novel therapeutics.
Reviews in medical virology 2004;14(4):255-70.
2004: Swanson Chad M; Puffer Bridget A; Ahmad K Muneer; Doms Robert W; Malim Michael H
Retroviral mRNA nuclear export elements regulate protein function and virion assembly.
The EMBO journal 2004;23(13):2632-40.
2004: Yuste Eloísa; Reeves Jacqueline D; Doms Robert W; Desrosiers Ronald C
Modulation of Env content in virions of simian immunodeficiency virus: correlation with cell surface expression and virion infectivity.
Journal of virology 2004;78(13):6775-85.
2004: Reeves Jacqueline D; Miamidian John L; Biscone Mark J; Lee Fang-Hua; Ahmad Navid; Pierson Theodore C; Doms Robert W
Impact of mutations in the coreceptor binding site on human immunodeficiency virus type 1 fusion, infection, and entry inhibitor sensitivity.
Journal of virology 2004;78(10):5476-85.
2004: Davis Carl W; Doms Robert W
HIV transmission: closing all the doors.
The Journal of experimental medicine 2004;199(8):1037-40.
2004: Mooij Petra; Nieuwenhuis Ivonne G; Knoop Christiaan J; Doms Robert W; Bogers Willy M J M; Ten Haaft Peter J F; Niphuis Henk; Koornstra Wim; Bieler Kurt; Köstler Josef; Morein Brør; Cafaro Aurelio; Ensoli Barbara; Wagner Ralf; Heeney Jonathan L
Qualitative T-helper responses to multiple viral antigens correlate with vaccine-induced immunity to simian/human immunodeficiency virus infection.
Journal of virology 2004;78(7):3333-42.
2004: Pöhlmann Stefan; Davis Carl; Meister Silke; Leslie George J; Otto Claas; Reeves Jacqueline D; Puffer Bridget A; Papkalla Armin; Krumbiegel Mandy; Marzi Andrea; Lorenz Steffen; Münch Jan; Doms Robert W; Kirchhoff Frank
Amino acid 324 in the simian immunodeficiency virus SIVmac V3 loop can confer CD4 independence and modulate the interaction with CCR5 and alternative coreceptors.
Journal of virology 2004;78(7):3223-32.
2004: Crystal Adam S; Morais Vanessa A; Fortna Ryan R; Carlin Dan; Pierson Theodore C; Wilson Christina A; Lee Virginia M-Y; Doms Robert W
Presenilin modulates Pen-2 levels posttranslationally by protecting it from proteasomal degradation.
Biochemistry 2004;43(12):3555-63.
2004: Burton Dennis R; Desrosiers Ronald C; Doms Robert W; Koff Wayne C; Kwong Peter D; Moore John P; Nabel Gary J; Sodroski Joseph; Wilson Ian A; Wyatt Richard T
HIV vaccine design and the neutralizing antibody problem.
Nature immunology 2004;5(3):233-6.
2004: Burton Dennis R; Desrosiers Ronald C; Doms Robert W; Feinberg Mark B; Gallo Robert C; Hahn Beatrice; Hoxie James A; Hunter Eric; Korber Bette; Landay Alan; Lederman Michael M; Lieberman Judy; McCune Joseph M; Moore John P; Nathanson Neal; Picker Louis; Richman Douglas; Rinaldo Charles; Stevenson Mario; Watkins David I; Wolinsky Steven M; Zack Jerome A
Public health. A sound rationale needed for phase III HIV-1 vaccine trials.
Science (New York, N.Y.) 2004;303(5656):316.
2004: Fortna Ryan R; Crystal Adam S; Morais Vanessa A; Pijak Donald S; Lee Virginia M-Y; Doms Robert W
Membrane topology and nicastrin-enhanced endoproteolysis of APH-1, a component of the gamma-secretase complex.
The Journal of biological chemistry 2004;279(5):3685-93.
2003: Veazey Ronald S; Klasse Per Johan; Ketas Thomas J; Reeves Jacqueline D; Piatak Michael; Kunstman Kevin; Kuhmann Shawn E; Marx Preston A; Lifson Jeffrey D; Dufour Jason; Mefford Megan; Pandrea Ivona; Wolinsky Steven M; Doms Robert W; DeMartino Julie A; Siciliano Salvatore J; Lyons Kathy; Springer Martin S; Moore John P
Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection.
The Journal of experimental medicine 2003;198(10):1551-62.
2003: Vödrös Dalma; Thorstensson Rigmor; Doms Robert W; Fenyö Eva Maria; Reeves Jacqueline D
Evolution of coreceptor use and CD4-independence in envelope clones derived from SIVsm-infected macaques.
Virology 2003;316(1):17-28.
2003: Wilson Christina A; Doms Robert W; Lee Virginia M-Y
Distinct presenilin-dependent and presenilin-independent gamma-secretases are responsible for total cellular Abeta production.
Journal of neuroscience research 2003;74(3):361-9.
2003: Kunstman Kevin J; Puffer Bridget; Korber Bette T; Kuiken Carla; Smith Una R; Kunstman Jennifer; Stanton Jennifer; Agy Michael; Shibata Riri; Yoder Anne D; Pillai Satish; Doms Robert W; Marx Preston; Wolinsky Steven M
Structure and function of CC-chemokine receptor 5 homologues derived from representative primate species and subspecies of the taxonomic suborders Prosimii and Anthropoidea.
Journal of virology 2003;77(22):12310-8.
2003: Otto Claas; Puffer Bridget A; Pöhlmann Stefan; Doms Robert W; Kirchhoff Frank
Mutations in the C3 region of human and simian immunodeficiency virus envelope have differential effects on viral infectivity, replication, and CD4-dependency.
Virology 2003;315(2):292-302.
2003: Morais Vanessa A; Crystal Adam S; Pijak Donald S; Carlin Dan; Costa Júlia; Lee Virginia M-Y; Doms Robert W
The transmembrane domain region of nicastrin mediates direct interactions with APH-1 and the gamma-secretase complex.
The Journal of biological chemistry 2003;278(44):43284-91.
2003: Moore John P; Doms Robert W
The entry of entry inhibitors: a fusion of science and medicine.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):10598-602.
2003: Chalasani Sreekanth H; Baribaud Frédéric; Coughlan Christine M; Sunshine Mary J; Lee Virginia M Y; Doms Robert W; Littman Dan R; Raper Jonathan A
The chemokine stromal cell-derived factor-1 promotes the survival of embryonic retinal ganglion cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(11):4601-12.
2003: Dehghani Houman; Puffer Bridget A; Doms Robert W; Hirsch Vanessa M
Unique pattern of convergent envelope evolution in simian immunodeficiency virus-infected rapid progressor macaques: association with CD4-independent usage of CCR5.
Journal of virology 2003;77(11):6405-18.
2003: Crystal Adam S; Morais Vanessa A; Pierson Theodore C; Pijak Donald S; Carlin Dan; Lee Virginia M-Y; Doms Robert W
Membrane topology of gamma-secretase component PEN-2.
The Journal of biological chemistry 2003;278(22):20117-23.
2003: Huse Jason T; Byant Damani; Yang Yaxiong; Pijak Donald S; D'Souza Ian; Lah James J; Lee Virginia M-Y; Doms Robert W; Cook David G
Endoproteolysis of beta-secretase (beta-site amyloid precursor protein-cleaving enzyme) within its catalytic domain. A potential mechanism for regulation.
The Journal of biological chemistry 2003;278(19):17141-9.
2003: Pöhlmann Stefan; Zhang Jie; Baribaud Frédéric; Chen Zhiwei; Leslie George J; Lin George; Granelli-Piperno Angela; Doms Robert W; Rice Charles M; McKeating Jane A
Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR.
Journal of virology 2003;77(7):4070-80.
2003: Lee Edward B; Skovronsky Daniel M; Abtahian Farhad; Doms Robert W; Lee Virginia M-Y
Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons.
The Journal of biological chemistry 2003;278(7):4458-66.
2003: Blanpain Cédric; Doranz Benjamin J; Bondue Antoine; Govaerts Cédric; De Leener Anne; Vassart Gilbert; Doms Robert W; Proudfoot Amanda; Parmentier Marc
The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle.
The Journal of biological chemistry 2003;278(7):5179-87.
2003: Pierson Theodore C; Doms Robert W
HIV-1 entry inhibitors: new targets, novel therapies.
Immunology letters 2003;85(2):113-8.
2003: Simmons Graham; Reeves Jacqueline D; Grogan Case C; Vandenberghe Luk H; Baribaud Frédéric; Whitbeck J Charles; Burke Emily; Buchmeier Michael J; Soilleux Elizabeth J; Riley James L; Doms Robert W; Bates Paul; Pöhlmann Stefan
DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells.
Virology 2003;305(1):115-23.
2003: Lin George; Simmons Graham; Pöhlmann Stefan; Baribaud Frédéric; Ni Houping; Leslie George J; Haggarty Beth S; Bates Paul; Weissman Drew; Hoxie James A; Doms Robert W
Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR.
Journal of virology 2003;77(2):1337-46.
2003: Lin George; Baribaud Frédéric; Romano Josephine; Doms Robert W; Hoxie James A
Identification of gp120 binding sites on CXCR4 by using CD4-independent human immunodeficiency virus type 2 Env proteins.
Journal of virology 2003;77(2):931-42.
2003: Pierson T C; Doms R W
HIV-1 entry and its inhibition.
Current topics in microbiology and immunology 2003;281():1-27.
2002: Reeves Jacqueline D; Gallo Stephen A; Ahmad Navid; Miamidian John L; Harvey Phoebe E; Sharron Matthew; Pohlmann Stefan; Sfakianos Jeffrey N; Derdeyn Cynthia A; Blumenthal Robert; Hunter Eric; Doms Robert W
Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(25):16249-54.
2002: Turville Stuart G; Cameron Paul U; Handley Amanda; Lin George; Pöhlmann Stefan; Doms Robert W; Cunningham Anthony L
Diversity of receptors binding HIV on dendritic cell subsets.
Nature immunology 2002;3(10):975-83.
2002: Biscone Mark J; Pierson Theodore C; Doms Robert W
Opportunities and challenges in targeting HIV entry.
Current opinion in pharmacology 2002;2(5):529-33.
2002: Baribaud Frédéric; Pöhlmann Stefan; Leslie George; Mortari Frank; Doms Robert W
Quantitative expression and virus transmission analysis of DC-SIGN on monocyte-derived dendritic cells.
Journal of virology 2002;76(18):9135-42.
2002: Wilson Christina A; Doms Robert W; Zheng Hui; Lee Virginia M-Y
Presenilins are not required for A beta 42 production in the early secretory pathway.
Nature neuroscience 2002;5(9):849-55.
2002: Baribaud Frédéric; Doms Robert W; Pöhlmann Stefan
The role of DC-SIGN and DC-SIGNR in HIV and Ebola virus infection: can potential therapeutics block virus transmission and dissemination?
Expert opinion on therapeutic targets 2002;6(4):423-31.
2002: Goldsmith Mark A; Doms Robert W
HIV entry: are all receptors created equal?
Nature immunology 2002;3(8):709-10.
2002: Reeves Jacqueline D; Doms Robert W
Human immunodeficiency virus type 2.
The Journal of general virology 2002;83(Pt 6):1253-65.
2002: Shattock Robin J; Doms Robert W
AIDS models: microbicides could learn from vaccines.
Nature medicine 2002;8(5):425.
2002: Huse Jason T; Liu Kangning; Pijak Donald S; Carlin Dan; Lee Virginia M-Y; Doms Robert W
Beta-secretase processing in the trans-Golgi network preferentially generates truncated amyloid species that accumulate in Alzheimer's disease brain.
The Journal of biological chemistry 2002;277(18):16278-84.
2002: Münch Jan; Ständker Ludger; Pöhlmann Stefan; Baribaud Frédéric; Papkalla Armin; Rosorius Olaf; Stauber Roland; Sass Gabriele; Heveker Nikolaus; Adermann Knut; Escher Sylvia; Klüver Enno; Doms Robert W; Forssmann Wolf-Georg; Kirchhoff Frank
Hemofiltrate CC chemokine 1[9-74] causes effective internalization of CCR5 and is a potent inhibitor of R5-tropic human immunodeficiency virus type 1 strains in primary T cells and macrophages.
Antimicrobial agents and chemotherapy 2002;46(4):982-90.
2002: Pöhlmann S; Doms R W
Evaluation of current approaches to inhibit HIV entry.
Current drug targets. Infectious disorders 2002;2(1):9-16.
2002: Soilleux Elizabeth J; Morris Lesley S; Leslie George; Chehimi Jihed; Luo Qi; Levroney Ernest; Trowsdale John; Montaner Luis J; Doms Robert W; Weissman Drew; Coleman Nicholas; Lee Benhur
Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro.
Journal of leukocyte biology 2002;71(3):445-57.
2002: Liu Kangning; Doms Robert W; Lee Virginia M-Y
Glu11 site cleavage and N-terminally truncated A beta production upon BACE overexpression.
Biochemistry 2002;41(9):3128-36.
2002: Edwards Terri G; Wyss Stéphanie; Reeves Jacqueline D; Zolla-Pazner Susan; Hoxie James A; Doms Robert W; Baribaud Frédéric
Truncation of the cytoplasmic domain induces exposure of conserved regions in the ectodomain of human immunodeficiency virus type 1 envelope protein.
Journal of virology 2002;76(6):2683-91.
2002: Puffer Bridget A; Pöhlmann Stefan; Edinger Aimee L; Carlin Dan; Sanchez Melissa D; Reitter Julie; Watry Debbie D; Fox Howard S; Desrosiers Ronald C; Doms Robert W
CD4 independence of simian immunodeficiency virus Envs is associated with macrophage tropism, neutralization sensitivity, and attenuated pathogenicity.
Journal of virology 2002;76(6):2595-605.
2002: Johnson Welkin E; Morgan Jennifer; Reitter Julie; Puffer Bridget A; Czajak Susan; Doms Robert W; Desrosiers Ronald C
A replication-competent, neutralization-sensitive variant of simian immunodeficiency virus lacking 100 amino acids of envelope.
Journal of virology 2002;76(5):2075-86.
2002: Jameson Brian; Baribaud Frédéric; Pöhlmann Stefan; Ghavimi Darlene; Mortari Frank; Doms Robert W; Iwasaki Akiko
Expression of DC-SIGN by dendritic cells of intestinal and genital mucosae in humans and rhesus macaques.
Journal of virology 2002;76(4):1866-75.
2001: Soilleux E J; Morris L S; Lee B; Pöhlmann S; Trowsdale J; Doms R W; Coleman N
Placental expression of DC-SIGN may mediate intrauterine vertical transmission of HIV.
The Journal of pathology 2001;195(5):586-92.
2001: Lee B; Leslie G; Soilleux E; O'Doherty U; Baik S; Levroney E; Flummerfelt K; Swiggard W; Coleman N; Malim M; Doms R W
cis Expression of DC-SIGN allows for more efficient entry of human and simian immunodeficiency viruses via CD4 and a coreceptor.
Journal of virology 2001;75(24):12028-38.
2001: Lin G; Lee B; Haggarty B S; Doms R W; Hoxie J A
CD4-independent use of Rhesus CCR5 by human immunodeficiency virus Type 2 implicates an electrostatic interaction between the CCR5 N terminus and the gp120 C4 domain.
Journal of virology 2001;75(22):10766-78.
2001: Pöhlmann S; Leslie G J; Edwards T G; Macfarlan T; Reeves J D; Hiebenthal-Millow K; Kirchhoff F; Baribaud F; Doms R W
DC-SIGN interactions with human immunodeficiency virus: virus binding and transfer are dissociable functions.
Journal of virology 2001;75(21):10523-6.
2001: Baribaud F; Pöhlmann S; Sparwasser T; Kimata M T; Choi Y K; Haggarty B S; Ahmad N; Macfarlan T; Edwards T G; Leslie G J; Arnason J; Reinhart T A; Kimata J T; Littman D R; Hoxie J A; Doms R W
Functional and antigenic characterization of human, rhesus macaque, pigtailed macaque, and murine DC-SIGN.
Journal of virology 2001;75(21):10281-9.
2001: Baribaud F; Edwards T G; Sharron M; Brelot A; Heveker N; Price K; Mortari F; Alizon M; Tsang M; Doms R W
Antigenically distinct conformations of CXCR4.
Journal of virology 2001;75(19):8957-67.
2001: Baribaud F; Pöhlmann S; Doms R W
The role of DC-SIGN and DC-SIGNR in HIV and SIV attachment, infection, and transmission.
Virology 2001;286(1):1-6.
2001: Baribaud F; Doms R W
The impact of chemokine receptor conformational heterogeneity on HIV infection.
Cellular and molecular biology (Noisy-le-Grand, France) 2001;47(4):653-60.
2001: Edwards T G; Hoffman T L; Baribaud F; Wyss S; LaBranche C C; Romano J; Adkinson J; Sharron M; Hoxie J A; Doms R W
Relationships between CD4 independence, neutralization sensitivity, and exposure of a CD4-induced epitope in a human immunodeficiency virus type 1 envelope protein.
Journal of virology 2001;75(11):5230-9.
2001: Blanpain C; Wittamer V; Vanderwinden J M; Boom A; Renneboog B; Lee B; Le Poul E; El Asmar L; Govaerts C; Vassart G; Doms R W; Parmentier M
Palmitoylation of CCR5 is critical for receptor trafficking and efficient activation of intracellular signaling pathways.
The Journal of biological chemistry 2001;276(26):23795-804.
2001: Pöhlmann S; Baribaud F; Lee B; Leslie G J; Sanchez M D; Hiebenthal-Millow K; Münch J; Kirchhoff F; Doms R W
DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus.
Journal of virology 2001;75(10):4664-72.
2001: Doranz B J; Filion L G; Diaz-Mitoma F; Sitar D S; Sahai J; Baribaud F; Orsini M J; Benovic J L; Cameron W; Doms R W
Safe use of the CXCR4 inhibitor ALX40-4C in humans.
AIDS research and human retroviruses 2001;17(6):475-86.
2001: Doms R W
Chemokine receptors and HIV entry.
AIDS (London, England) 2001;15 Suppl 1():S34-5.
2001: Huse J T; Doms R W
Neurotoxic traffic: uncovering the mechanics of amyloid production in Alzheimer's disease.
Traffic (Copenhagen, Denmark) 2001;2(2):75-81.
2001: Pöhlmann S; Soilleux E J; Baribaud F; Leslie G J; Morris L S; Trowsdale J; Lee B; Coleman N; Doms R W
DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2670-5.
2000: Doms R W; Trono D
The plasma membrane as a combat zone in the HIV battlefield.
Genes & development 2000;14(21):2677-88.
2000: Puffer B A; Sharron M; Coughlan C M; Baribaud F; McManus C M; Lee B; David J; Price K; Horuk R; Tsang M; Doms R W
Expression and coreceptor function of APJ for primate immunodeficiency viruses.
Virology 2000;276(2):435-44.
2000: Doms R W
Beyond receptor expression: the influence of receptor conformation, density, and affinity in HIV-1 infection.
Virology 2000;276(2):229-37.
2000: Doms R W; Moore J P
HIV-1 membrane fusion: targets of opportunity.
The Journal of cell biology 2000;151(2):F9-14.
2000: Hoffman T L; Canziani G; Jia L; Rucker J; Doms R W
A biosensor assay for studying ligand-membrane receptor interactions: binding of antibodies and HIV-1 Env to chemokine receptors.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(21):11215-20.
2000: Huse J T; Pijak D S; Leslie G J; Lee V M; Doms R W
Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase.
The Journal of biological chemistry 2000;275(43):33729-37.
2000: Blanpain C; Lee B; Tackoen M; Puffer B; Boom A; Libert F; Sharron M; Wittamer V; Vassart G; Doms R W; Parmentier M
Multiple nonfunctional alleles of CCR5 are frequent in various human populations.
Blood 2000;96(5):1638-45.
2000: Edinger A L; Ahuja M; Sung T; Baxter K C; Haggarty B; Doms R W; Hoxie J A
Characterization and epitope mapping of neutralizing monoclonal antibodies produced by immunization with oligomeric simian immunodeficiency virus envelope protein.
Journal of virology 2000;74(17):7922-35.
2000: Huse J T; Doms R W
Closing in on the amyloid cascade: recent insights into the cell biology of Alzheimer's disease.
Molecular neurobiology 2000;22(1-3):81-98.
2000: Sharron M; Pöhlmann S; Price K; Lolis E; Tsang M; Kirchhoff F; Doms R W; Lee B
Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes.
Blood 2000;96(1):41-9.
2000: Pöhlmann S; Lee B; Meister S; Krumbiegel M; Leslie G; Doms R W; Kirchhoff F
Simian immunodeficiency virus utilizes human and sooty mangabey but not rhesus macaque STRL33 for efficient entry.
Journal of virology 2000;74(11):5075-82.
2000: Liu Q H; Williams D A; McManus C; Baribaud F; Doms R W; Schols D; De Clercq E; Kotlikoff M I; Collman R G; Freedman B D
HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4832-7.
2000: Skovronsky D M; Pijak D S; Doms R W; Lee V M
A distinct ER/IC gamma-secretase competes with the proteasome for cleavage of APP.
Biochemistry 2000;39(4):810-7.
2000: Skovronsky D M; Moore D B; Milla M E; Doms R W; Lee V M
Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network.
The Journal of biological chemistry 2000;275(4):2568-75.
2000: Liao H X; Etemad-Moghadam B; Montefiori D C; Sun Y; Sodroski J; Scearce R M; Doms R W; Thomasch J R; Robinson S; Letvin N L; Haynes B F
Induction of antibodies in guinea pigs and rhesus monkeys against the human immunodeficiency virus type 1 envelope: neutralization of nonpathogenic and pathogenic primary isolate simian/human immunodeficiency virus strains.
Journal of virology 2000;74(1):254-63.
2000: Coughlan C M; McManus C M; Sharron M; Gao Z; Murphy D; Jaffer S; Choe W; Chen W; Hesselgesser J; Gaylord H; Kalyuzhny A; Lee V M; Wolf B; Doms R W; Kolson D L
Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons.
Neuroscience 2000;97(3):591-600.
2000: McManus C M; Doms R W
Fusion mediated by the HIV-1 envelope protein.
Sub-cellular biochemistry 2000;34():457-81.
1999: Blanpain C; Doranz B J; Vakili J; Rucker J; Govaerts C; Baik S S; Lorthioir O; Migeotte I; Libert F; Baleux F; Vassart G; Doms R W; Parmentier M
Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein.
The Journal of biological chemistry 1999;274(49):34719-27.
1999: Doranz B J; Baik S S; Doms R W
Use of a gp120 binding assay to dissect the requirements and kinetics of human immunodeficiency virus fusion events.
Journal of virology 1999;73(12):10346-58.
1999: LaBranche C C; Hoffman T L; Romano J; Haggarty B S; Edwards T G; Matthews T J; Doms R W; Hoxie J A
Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity.
Journal of virology 1999;73(12):10310-9.
1999: Blanpain C; Migeotte I; Lee B; Vakili J; Doranz B J; Govaerts C; Vassart G; Doms R W; Parmentier M
CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist.
Blood 1999;94(6):1899-905.
1999: Pritsker M; Rucker J; Hoffman T L; Doms R W; Shai Y
Effect of nonpolar substitutions of the conserved Phe11 in the fusion peptide of HIV-1 gp41 on its function, structure, and organization in membranes.
Biochemistry 1999;38(35):11359-71.
1999: Wilson C A; Doms R W; Lee V M
Intracellular APP processing and A beta production in Alzheimer disease.
Journal of neuropathology and experimental neurology 1999;58(8):787-94.
1999: Liu Z Q; Muhkerjee S; Sahni M; McCormick-Davis C; Leung K; Li Z; Gattone V H; Tian C; Doms R W; Hoffman T L; Raghavan R; Narayan O; Stephens E B
Derivation and biological characterization of a molecular clone of SHIV(KU-2) that causes AIDS, neurological disease, and renal disease in rhesus macaques.
Virology 1999;260(2):295-307.
1999: Edinger A L; Clements J E; Doms R W
Chemokine and orphan receptors in HIV-2 and SIV tropism and pathogenesis.
Virology 1999;260(2):211-21.
1999: Baik S S; Doms R W; Doranz B J
HIV and SIV gp120 binding does not predict coreceptor function.
Virology 1999;259(2):267-73.
1999: Blanpain C; Lee B; Vakili J; Doranz B J; Govaerts C; Migeotte I; Sharron M; Dupriez V; Vassart G; Doms R W; Parmentier M
Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activity.
The Journal of biological chemistry 1999;274(27):18902-8.
1999: Hoffman T L; LaBranche C C; Zhang W; Canziani G; Robinson J; Chaiken I; Hoxie J A; Doms R W
Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(11):6359-64.
1999: Edinger A L; Blanpain C; Kunstman K J; Wolinsky S M; Parmentier M; Doms R W
Functional dissection of CCR5 coreceptor function through the use of CD4-independent simian immunodeficiency virus strains.
Journal of virology 1999;73(5):4062-73.
1999: Lee B; Sharron M; Montaner L J; Weissman D; Doms R W
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5215-20.
1999: Lee B; Sharron M; Blanpain C; Doranz B J; Vakili J; Setoh P; Berg E; Liu G; Guy H R; Durell S R; Parmentier M; Chang C N; Price K; Tsang M; Doms R W
Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function.
The Journal of biological chemistry 1999;274(14):9617-26.
1999: Doranz B J; Orsini M J; Turner J D; Hoffman T L; Berson J F; Hoxie J A; Peiper S C; Brass L F; Doms R W
Identification of CXCR4 domains that support coreceptor and chemokine receptor functions.
Journal of virology 1999;73(4):2752-61.
1999: Martin V; Ronde P; Unett D; Wong A; Hoffman T L; Edinger A L; Doms R W; Funk C D
Leukotriene binding, signaling, and analysis of HIV coreceptor function in mouse and human leukotriene B4 receptor-transfected cells.
The Journal of biological chemistry 1999;274(13):8597-603.
1999: Lee B; Ratajczak J; Doms R W; Gewirtz A M; Ratajczak M Z
Coreceptor/chemokine receptor expression on human hematopoietic cells: biological implications for human immunodeficiency virus-type 1 infection.
Blood 1999;93(4):1145-56.
1999: Hoffman T L; Doms R W
HIV-1 envelope determinants for cell tropism and chemokine receptor use.
Molecular membrane biology 1999;16(1):57-65.
1999: Albright A V; Shieh J T; Itoh T; Lee B; Pleasure D; O'Connor M J; Doms R W; González-Scarano F
Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates.
Journal of virology 1999;73(1):205-13.
1998: Hoxie J A; LaBranche C C; Endres M J; Turner J D; Berson J F; Doms R W; Matthews T J
CD4-independent utilization of the CXCR4 chemokine receptor by HIV-1 and HIV-2.
Journal of reproductive immunology 1998;41(1-2):197-211.
1998: Rucker J; Doms R W
Chemokine receptors as HIV coreceptors: implications and interactions.
AIDS research and human retroviruses 1998;14 Suppl 3():S241-6.
1998: Edinger A L; Hoffman T L; Sharron M; Lee B; Yi Y; Choe W; Kolson D L; Mitrovic B; Zhou Y; Faulds D; Collman R G; Hesselgesser J; Horuk R; Doms R W
An orphan seven-transmembrane domain receptor expressed widely in the brain functions as a coreceptor for human immunodeficiency virus type 1 and simian immunodeficiency virus.
Journal of virology 1998;72(10):7934-40.
1998: Edinger A L; Hoffman T L; Sharron M; Lee B; O'Dowd B; Doms R W
Use of GPR1, GPR15, and STRL33 as coreceptors by diverse human immunodeficiency virus type 1 and simian immunodeficiency virus envelope proteins.
Virology 1998;249(2):367-78.
1998: Hoffman T L; Stephens E B; Narayan O; Doms R W
HIV type I envelope determinants for use of the CCR2b, CCR3, STRL33, and APJ coreceptors.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(19):11360-5.
1998: Lee B; Doranz B J; Rana S; Yi Y; Mellado M; Frade J M; Martinez-A C; O'Brien S J; Dean M; Collman R G; Doms R W
Influence of the CCR2-V64I polymorphism on human immunodeficiency virus type 1 coreceptor activity and on chemokine receptor function of CCR2b, CCR3, CCR5, and CXCR4.
Journal of virology 1998;72(9):7450-8.
1998: Berson J F; Doms R W
Structure-function studies of the HIV-1 coreceptors.
Seminars in immunology 1998;10(3):237-48.
1998: Samson M; Edinger A L; Stordeur P; Rucker J; Verhasselt V; Sharron M; Govaerts C; Mollereau C; Vassart G; Doms R W; Parmentier M
ChemR23, a putative chemoattractant receptor, is expressed in monocyte-derived dendritic cells and macrophages and is a coreceptor for SIV and some primary HIV-1 strains.
European journal of immunology 1998;28(5):1689-700.
1998: Skovronsky D M; Doms R W; Lee V M
Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture.
The Journal of cell biology 1998;141(4):1031-9.
1998: Shieh J T; Albright A V; Sharron M; Gartner S; Strizki J; Doms R W; González-Scarano F
Chemokine receptor utilization by human immunodeficiency virus type 1 isolates that replicate in microglia.
Journal of virology 1998;72(5):4243-9.
1998: Cho M W; Lee M K; Carney M C; Berson J F; Doms R W; Martin M A
Identification of determinants on a dualtropic human immunodeficiency virus type 1 envelope glycoprotein that confer usage of CXCR4.
Journal of virology 1998;72(3):2509-15.
1998: Horuk R; Hesselgesser J; Zhou Y; Faulds D; Halks-Miller M; Harvey S; Taub D; Samson M; Parmentier M; Rucker J; Doranz B J; Doms R W
The CC chemokine I-309 inhibits CCR8-dependent infection by diverse HIV-1 strains.
The Journal of biological chemistry 1998;273(1):386-91.
1998: Hoffman T L; Doms R W
Chemokines and coreceptors in HIV/SIV-host interactions.
AIDS (London, England) 1998;12 Suppl A():S17-26.
1998: Lee B; Doranz B J; Ratajczak M Z; Doms R W
An intricate Web: chemokine receptors, HIV-1 and hematopoiesis.
Stem cells (Dayton, Ohio) 1998;16(2):79-88.
1997: Edinger A L; Mankowski J L; Doranz B J; Margulies B J; Lee B; Rucker J; Sharron M; Hoffman T L; Berson J F; Zink M C; Hirsch V M; Clements J E; Doms R W
CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14742-7.
1997: Forman M S; Cook D G; Leight S; Doms R W; Lee V M
Differential effects of the swedish mutant amyloid precursor protein on beta-amyloid accumulation and secretion in neurons and nonneuronal cells.
The Journal of biological chemistry 1997;272(51):32247-53.
1997: Rucker J; Edinger A L; Sharron M; Samson M; Lee B; Berson J F; Yi Y; Margulies B; Collman R G; Doranz B J; Parmentier M; Doms R W
Utilization of chemokine receptors, orphan receptors, and herpesvirus-encoded receptors by diverse human and simian immunodeficiency viruses.
Journal of virology 1997;71(12):8999-9007.
1997: Doranz B J; Grovit-Ferbas K; Sharron M P; Mao S H; Goetz M B; Daar E S; Doms R W; O'Brien W A
A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor.
The Journal of experimental medicine 1997;186(8):1395-400.
1997: Hoffman T L; MacGregor R R; Burger H; Mick R; Doms R W; Collman R G
CCR5 genotypes in sexually active couples discordant for human immunodeficiency virus type 1 infection status.
The Journal of infectious diseases 1997;176(4):1093-6.
1997: Cook D G; Forman M S; Sung J C; Leight S; Kolson D L; Iwatsubo T; Lee V M; Doms R W
Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells.
Nature medicine 1997;3(9):1021-3.
1997: Doms R W; Peiper S C
Unwelcomed guests with master keys: how HIV uses chemokine receptors for cellular entry.
Virology 1997;235(2):179-90.
1997: Doranz B J; Lu Z H; Rucker J; Zhang T Y; Sharron M; Cen Y H; Wang Z X; Guo H H; Du J G; Accavitti M A; Doms R W; Peiper S C
Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1.
Journal of virology 1997;71(9):6305-14.
1997: Chyung A S; Greenberg B D; Cook D G; Doms R W; Lee V M
Novel beta-secretase cleavage of beta-amyloid precursor protein in the endoplasmic reticulum/intermediate compartment of NT2N cells.
The Journal of cell biology 1997;138(3):671-80.
1997: Lu Z; Berson J F; Chen Y; Turner J D; Zhang T; Sharron M; Jenks M H; Wang Z; Kim J; Rucker J; Hoxie J A; Peiper S C; Doms R W
Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(12):6426-31.
1997: Edinger A L; Amedee A; Miller K; Doranz B J; Endres M; Sharron M; Samson M; Lu Z H; Clements J E; Murphey-Corb M; Peiper S C; Parmentier M; Broder C C; Doms R W
Differential utilization of CCR5 by macrophage and T cell tropic simian immunodeficiency virus strains.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):4005-10.
1997: Rana S; Besson G; Cook D G; Rucker J; Smyth R J; Yi Y; Turner J D; Guo H H; Du J G; Peiper S C; Lavi E; Samson M; Libert F; Liesnard C; Vassart G; Doms R W; Parmentier M; Collman R G
Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation.
Journal of virology 1997;71(4):3219-27.
1997: Doranz B J; Berson J F; Rucker J; Doms R W
Chemokine receptors as fusion cofactors for human immunodeficiency virus type 1 (HIV-1).
Immunologic research 1997;16(1):15-28.
1997: Rucker J; Doranz B J; Edinger A L; Long D; Berson J F; Doms R W
Cell-cell fusion assay to study role of chemokine receptors in human immunodeficiency virus type 1 entry.
Methods in enzymology 1997;288():118-33.
1996: Endres M J; Clapham P R; Marsh M; Ahuja M; Turner J D; McKnight A; Thomas J F; Stoebenau-Haggarty B; Choe S; Vance P J; Wells T N; Power C A; Sutterwala S S; Doms R W; Landau N R; Hoxie J A
CD4-independent infection by HIV-2 is mediated by fusin/CXCR4.
Cell 1996;87(4):745-56.
1996: Rucker J; Samson M; Doranz B J; Libert F; Berson J F; Yi Y; Smyth R J; Collman R G; Broder C C; Vassart G; Doms R W; Parmentier M
Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity.
Cell 1996;87(3):437-46.
1996: Cook D G; Turner R S; Kolson D L; Lee V M; Doms R W
Vaccinia virus serves as an efficient vector for expressing heterologous proteins in human NTera 2 neurons.
The Journal of comparative neurology 1996;374(4):481-92.
1996: Berson J F; Long D; Doranz B J; Rucker J; Jirik F R; Doms R W
A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains.
Journal of virology 1996;70(9):6288-95.
1996: Cook D G; Sung J C; Golde T E; Felsenstein K M; Wojczyk B S; Tanzi R E; Trojanowski J Q; Lee V M; Doms R W
Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9223-8.
1996: Samson M; Libert F; Doranz B J; Rucker J; Liesnard C; Farber C M; Saragosti S; Lapoumeroulie C; Cognaux J; Forceille C; Muyldermans G; Verhofstede C; Burtonboy G; Georges M; Imai T; Rana S; Yi Y; Smyth R J; Collman R G; Doms R W; Vassart G; Parmentier M
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene.
Nature 1996;382(6593):722-5.
1996: Doranz B J; Rucker J; Yi Y; Smyth R J; Samson M; Peiper S C; Parmentier M; Collman R G; Doms R W
A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors.
Cell 1996;85(7):1149-58.
1996: Chunduru S K; Sutherland R M; Stewart G A; Doms R W; Paterson Y
Exploitation of the Vbeta8.2 T cell receptor in protection against experimental autoimmune encephalomyelitis using a live vaccinia virus vector.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(12):4940-5.
1996: Richardson T M; Stryjewski B L; Broder C C; Hoxie J A; Mascola J R; Earl P L; Doms R W
Humoral response to oligomeric human immunodeficiency virus type 1 envelope protein.
Journal of virology 1996;70(2):753-62.
1995: Wojczyk B; Shakin-Eshleman S H; Doms R W; Xiang Z Q; Ertl H C; Wunner W H; Spitalnik S L
Stable secretion of a soluble, oligomeric form of rabies virus glycoprotein: influence of N-glycan processing on secretion.
Biochemistry 1995;34(8):2599-609.
1994: Broder C C; Earl P L; Long D; Abedon S T; Moss B; Doms R W
Antigenic implications of human immunodeficiency virus type 1 envelope quaternary structure: oligomer-specific and -sensitive monoclonal antibodies.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11699-703.
1994: Long D; Berson J F; Cook D G; Doms R W
Characterization of human immunodeficiency virus type 1 gp120 binding to liposomes containing galactosylceramide.
Journal of virology 1994;68(9):5890-8.
1994: Earl P L; Broder C C; Long D; Lee S A; Peterson J; Chakrabarti S; Doms R W; Moss B
Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities.
Journal of virology 1994;68(5):3015-26.
1994: Cook D G; Lee V M; Doms R W
Expression of foreign proteins in a human neuronal system.
Methods in cell biology 1994;43 Pt A():289-303.
1993: Doms R W; Lamb R A; Rose J K; Helenius A
Folding and assembly of viral membrane proteins.
Virology 1993;193(2):545-62.
1992: Earl P L; Doms R W; Moss B
Multimeric CD4 binding exhibited by human and simian immunodeficiency virus envelope protein dimers.
Journal of virology 1992;66(9):5610-4.
1991: Earl P L; Moss B; Doms R W
Folding, interaction with GRP78-BiP, assembly, and transport of the human immunodeficiency virus type 1 envelope protein.
Journal of virology 1991;65(4):2047-55.
1991: Doms R W; Earl P L; Moss B
The assembly of the HIV-1 env glycoprotein into dimers and tetramers.
Advances in experimental medicine and biology 1991;300():203-19; discussion 220-1.
1990: Doms R W; Blumenthal R; Moss B
Fusion of intra- and extracellular forms of vaccinia virus with the cell membrane.
Journal of virology 1990;64(10):4884-92.
1990: Puri A; Booy F P; Doms R W; White J M; Blumenthal R
Conformational changes and fusion activity of influenza virus hemagglutinin of the H2 and H3 subtypes: effects of acid pretreatment.
Journal of virology 1990;64(8):3824-32.
1990: Doms R W; Earl P L; Chakrabarti S; Moss B
Human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus env proteins possess a functionally conserved assembly domain.
Journal of virology 1990;64(7):3537-40.
1990: Earl P L; Doms R W; Moss B
Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(2):648-52.
1989: Doms R W; Russ G; Yewdell J W
Brefeldin A redistributes resident and itinerant Golgi proteins to the endoplasmic reticulum.
The Journal of cell biology 1989;109(1):61-72.

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