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Jinsheng Dong

Research Profile

Chemicals & Drugs

Living Beings

Saccharomyces cerevisiae

Concepts & Ideas

Protein Structure, Tertiary

Phenomena

Anatomy

Ribosomes

Physiology

Co-author Network

Publications

TOP 3
Byung-Sik Shin; Sarah E Walker; Jinsheng Dong; Joo-Ran Kim; Jon R Lorsch; Thomas E Dever
Initiation factor eIF2γ promotes eIF2-GTP-Met-tRNAi(Met) ternary complex binding to the 40S ribosome.
Jinsheng Dong; Jagpreet S Nanda; Hafsa Rahman; Margaret R Pruitt; Byung-Sik Shin; Chi-Ming Wong; Jon R Lorsch; Alan G Hinnebusch
Genetic identification of yeast 18S rRNA residues required for efficient recruitment of initiator tRNA(Met) and AUG selection.
Chi-Ming Wong; Hongfang Qiu; Cuihua Hu; Jinsheng Dong; Alan G Hinnebusch
Yeast cap binding complex impedes recruitment of cleavage factor IA to weak termination sites.

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All Publications

2011: Byung-Sik Shin; Sarah E Walker; Jinsheng Dong; Joo-Ran Kim; Jon R Lorsch; Thomas E Dever
Initiation factor eIF2γ promotes eIF2-GTP-Met-tRNAi(Met) ternary complex binding to the 40S ribosome.
Nature structural & molecular biology 2011;18(11):1227-34.
2008: Jinsheng Dong; Jagpreet S Nanda; Hafsa Rahman; Margaret R Pruitt; Byung-Sik Shin; Chi-Ming Wong; Jon R Lorsch; Alan G Hinnebusch
Genetic identification of yeast 18S rRNA residues required for efficient recruitment of initiator tRNA(Met) and AUG selection.
Genes & development 2008;22(16):2242-55.
2007: Chi-Ming Wong; Hongfang Qiu; Cuihua Hu; Jinsheng Dong; Alan G Hinnebusch
Yeast cap binding complex impedes recruitment of cleavage factor IA to weak termination sites.
Molecular and cellular biology 2007;27(18):6520-31.
2005: Jinsheng Dong; Ruby Lai; Jennifer L Jennings; Andrew J Link; Alan G Hinnebusch
The novel ATP-binding cassette protein ARB1 is a shuttling factor that stimulates 40S and 60S ribosome biogenesis.
Molecular and cellular biology 2005;25(22):9859-73.
2005: Madhusudan Dey; Bruce Trieselmann; Emily G Locke; Jingfang Lu; Chune Cao; Arvin C Dar; Thanuja Krishnamoorthy; Jinsheng Dong; Frank Sicheri; Thomas E Dever
PKR and GCN2 kinases and guanine nucleotide exchange factor eukaryotic translation initiation factor 2B (eIF2B) recognize overlapping surfaces on eIF2alpha.
Molecular and cellular biology 2005;25(8):3063-75.
2004: Jinsheng Dong; Ruby Lai; Klaus Nielsen; Christie A Fekete; Hongfang Qiu; Alan G Hinnebusch
The essential ATP-binding cassette protein RLI1 functions in translation by promoting preinitiation complex assembly.
The Journal of biological chemistry 2004;279(40):42157-68.
2004: Sungpil Yoon; Chhabi K Govind; Hongfang Qiu; Soon-ja Kim; Jinsheng Dong; Alan G Hinnebusch
Recruitment of the ArgR/Mcm1p repressor is stimulated by the activator Gcn4p: a self-checking activation mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11713-8.
2002: Minerva Garcia-Barrio; Jinsheng Dong; Vera A Cherkasova; Xiaolong Zhang; Fan Zhang; Sandra Ufano; Ruby Lai; Jun Qin; Alan G Hinnebusch
Serine 577 is phosphorylated and negatively affects the tRNA binding and eIF2alpha kinase activities of GCN2.
The Journal of biological chemistry 2002;277(34):30675-83.
2002: Hongfang Qiu; Cuihua Hu; Jinsheng Dong; Alan G Hinnebusch
Mutations that bypass tRNA binding activate the intrinsically defective kinase domain in GCN2.
Genes & development 2002;16(10):1271-80.
2001: Hongfang Qiu; Jinsheng Dong; Cuihua Hu; C S Francklyn; Alan G Hinnebusch
The tRNA-binding moiety in GCN2 contains a dimerization domain that interacts with the kinase domain and is required for tRNA binding and kinase activation.
The EMBO journal 2001;20(6):1425-38.
2000: Jinsheng Dong; Hongfang Qiu; Minerva Garcia-Barrio; J Anderson; Alan G Hinnebusch
Uncharged tRNA activates GCN2 by displacing the protein kinase moiety from a bipartite tRNA-binding domain.
Molecular cell 2000;6(2):269-79.
2000: Minerva Garcia-Barrio; Jinsheng Dong; Sandra Ufano; Alan G Hinnebusch
Association of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activation.
The EMBO journal 2000;19(8):1887-99.