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Rachelle Donn

Research Profile

Disorders

Physiology

Genes & Molecular Sequences

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Great Britain

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Publications

TOP 3
Anne Hinks; Paul Martin; Jon Packham; Athimalaipet V Ramanan; Carmel J Stock; Marc Sudman; Susan Thompson; Wendy Thomson; Thomas G Day; Rachelle Donn
Autoinflammatory gene polymorphisms and susceptibility to UK juvenile idiopathic arthritis.
Elaine Beaulieu; L Green; L Elsby; Zaynab Alourfi; E F Morand; David W Ray; Rachelle Donn
Identification of a novel cell type-specific intronic enhancer of macrophage migration inhibitory factor (MIF) and its regulation by mithramycin.
Andrew McMaster; Maryam Jangani; Paula Sommer; Namshik Han; Andy Brass; Stephen Beesley; Weiqun Lu; Andrew Berry; Andrew Loudon; Rachelle Donn; David W Ray
Ultradian cortisol pulsatility encodes a distinct, biologically important signal.

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All Publications

2013: Anne Hinks; Paul Martin; Jon Packham; Athimalaipet V Ramanan; Carmel J Stock; Marc Sudman; Susan Thompson; Wendy Thomson; Thomas G Day; Rachelle Donn
Autoinflammatory gene polymorphisms and susceptibility to UK juvenile idiopathic arthritis.
Pediatric rheumatology online journal 2013;11(1):14.
2011: Elaine Beaulieu; L Green; L Elsby; Zaynab Alourfi; E F Morand; David W Ray; Rachelle Donn
Identification of a novel cell type-specific intronic enhancer of macrophage migration inhibitory factor (MIF) and its regulation by mithramycin.
Clinical and experimental immunology 2011;163(2):178-88.
2011: Andrew McMaster; Maryam Jangani; Paula Sommer; Namshik Han; Andy Brass; Stephen Beesley; Weiqun Lu; Andrew Berry; Andrew Loudon; Rachelle Donn; David W Ray
Ultradian cortisol pulsatility encodes a distinct, biologically important signal.
PloS one 2011;6(1):e15766.
2010: Laura M Elsby; G Orozco; J Denton; Jane Worthington; David W Ray; Rachelle Donn
Functional evaluation of TNFAIP3 (A20) in rheumatoid arthritis.
Clinical and experimental rheumatology 2010;28(5):708-14.
2010: Andy Berry; L Matthews; M Jangani; J Plumb; Stuart N Farrow; N Buchan; P A Wilson; D Singh; D W Ray; Rachelle Donn
Interferon-inducible factor 16 is a novel modulator of glucocorticoid action.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(6):1700-13.
2009: Laura M Elsby; Rachelle Donn; Zaynab Alourfi; Laura M Green; Elaine Beaulieu; David W Ray
Hypoxia and glucocorticoid signaling converge to regulate macrophage migration inhibitory factor gene expression.
Arthritis and rheumatism 2009;60(8):2220-31.
2008: T G Day; Athimalaipet V Ramanan; Anne Hinks; Rebecca Lamb; J Packham; C Wise; M Punaro; Rachelle Donn
Autoinflammatory genes and susceptibility to psoriatic juvenile idiopathic arthritis.
Arthritis and rheumatism 2008;58(7):2142-6.
2008: Kay Chapman; Atsushi Takahashi; Ingrid Meulenbelt; Chris Watson; Julio A Rodriguez-Lopez; Rainer Egli; Aspasia Tsezou; Konstantinos N Malizos; Margreet Kloppenburg; Dongquan Shi; Lorraine Southam; Ruud van der Breggen; Rachelle Donn; Jianghui Qin; Michael Doherty; P Eline Slagboom; Gillian Wallis; Naoyuki Kamatani; Qing Jiang; Antonio Gonzalez; John Loughlin; Shiro Ikegawa
A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility.
Human molecular genetics 2008;17(10):1497-504.
2008: A McMaster; T Chambers; Q-J Meng; S Grundy; Andrew S I Loudon; Rachelle Donn; David W Ray
Real-time analysis of gene regulation by glucocorticoid hormones.
The Journal of endocrinology 2008;197(2):205-11.
2008: Rachelle Donn; Stuart Ellison; Rebecca Lamb; Thomas Day; Eileen Baildam; Athimalaipet V Ramanan
Genetic loci contributing to hemophagocytic lymphohistiocytosis do not confer susceptibility to systemic-onset juvenile idiopathic arthritis.
Arthritis and rheumatism 2008;58(3):869-74.
2008: Timothy Radstake; Jaap Fransen; P L C M van Riel; Erik J M Toonen; Marieke Coenen; Rachelle Donn
Functional variants of the macrophage migration inhibitory factor do not infer risk of cardiovascular disease in rheumatoid arthritis.
Annals of the rheumatic diseases 2008;67(1):134-5.
2007: Wendy Thomson; Anne Barton; Xiayi Ke; Stephen Eyre; Anne Hinks; John Bowes; Rachelle Donn; Deborah Symmons; Samantha L Hider; Ian N Bruce; Anthony G Wilson; Ioanna Marinou; Ann Morgan; Paul Emery; Angela Carter; Sophia Steer; Lynne Hocking; David M Reid; Paul Wordsworth; Pille Harrison; David Strachan; Jane Worthington
Rheumatoid arthritis association at 6q23.
Nature genetics 2007;39(12):1431-3.
2007: Timothy Radstake; Jaap Fransen; Erik J M Toonen; Marieke Coenen; Agnes E Eijsbouts; Rachelle Donn; F H J van den Hoogen; P L C M van Riel
Macrophage migration inhibitory factor polymorphisms do not predict therapeutic response to glucocorticoids or to tumour necrosis factor alpha-neutralising treatments in rheumatoid arthritis.
Annals of the rheumatic diseases 2007;66(11):1525-30.
2007: Marina Vivarelli; Leila E D'Urbano; Antonella Insalaco; Mark Lunt; Francine Jury; Alberto Tozzi; Angelo Ravelli; Alberto Martini; Rachelle Donn; de benedetti fabrizio
Macrophage migration inhibitory factor (MIF) and oligoarticular juvenile idiopathic arthritis (o-JIA): association of MIF promoter polymorphisms with response to intra-articular glucocorticoids.
Clinical and experimental rheumatology 2007;25(5):775-81.
2007: Rachelle Donn; Debbie Payne; David Ray
Glucocorticoid receptor gene polymorphisms and susceptibility to rheumatoid arthritis.
Clinical endocrinology 2007;67(3):342-5.
2007: Rebecca Lamb; Wendy Thomson; Emma M Ogilvie; Rachelle Donn
Positive association of SLC26A2 gene polymorphisms with susceptibility to systemic-onset juvenile idiopathic arthritis.
Arthritis and rheumatism 2007;56(4):1286-91.
2007: Mark S Fife; Laura Gathercole; Emma M Ogilvie; Carmel J W Stock; Lisa F Mack; Rachelle Donn; Wendy Thomson; Patricia Woo
No evidence for genetic association of interferon regulatory factor 1 in juvenile idiopathic arthritis.
Arthritis and rheumatism 2007;56(3):972-6.
2007: Rachelle Donn; Andy Berry; Adam Stevens; Stuart N Farrow; Joanna Betts; Richard Stevens; Chris Clayton; Jixian Wang; Linda Warnock; Jane Worthington; Laurie Scott; Simon Graham; David Ray
Use of gene expression profiling to identify a novel glucocorticoid sensitivity determining gene, BMPRII.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(2):402-14.
2006: Alex Kudrin; Martin Scott; Steven Martin; Chun-wa Chung; Rachelle Donn; Andrew McMaster; Stuart Ellison; David Ray; Keith Ray; Michael Binks
Human macrophage migration inhibitory factor: a proven immunomodulatory cytokine?
The Journal of biological chemistry 2006;281(40):29641-51.
2006: Eleftheria Zeggini; J Packham; Rachelle Donn; Paul Wordsworth; A Hall; Wendy Thomson
Association of HLA-DRB1*13 with susceptibility to uveitis in juvenile idiopathic arthritis in two independent data sets.
Rheumatology (Oxford, England) 2006;45(8):972-4.
2006: Danielle Carrick; Patricia C Chulada; Rachelle Donn; Martina Fabris; Janet M McNicholl; William C Whitworth; Perry Blackshear
Genetic variations in ZFP36 and their possible relationship to autoimmune diseases.
Journal of autoimmunity 2006;26(3):182-96.
2005: Rebecca Lamb; Wendy Thomson; Emma M Ogilvie; Rachelle Donn
Wnt-1-inducible signaling pathway protein 3 and susceptibility to juvenile idiopathic arthritis.
Arthritis and rheumatism 2005;52(11):3548-53.
2005: L J Gibbons; Wendy Thomson; Eleftheria Zeggini; Jane Worthington; Anne Barton; Stephen Eyre; Rachelle Donn; Anne Hinks
The type 1 diabetes susceptibility gene SUMO4 at IDDM5 is not associated with susceptibility to rheumatoid arthritis or juvenile idiopathic arthritis.
Rheumatology (Oxford, England) 2005;44(11):1390-3.
2005: Timothy Radstake; Fred C G J Sweep; Paco M J Welsing; Barbara Franke; Sita H H M Vermeulen; Anneke Geurts-Moespot; Thierry Calandra; Rachelle Donn; P L C M van Riel
Correlation of rheumatoid arthritis severity with the genetic functional variants and circulating levels of macrophage migration inhibitory factor.
Arthritis and rheumatism 2005;52(10):3020-9.
2005: Anne Hinks; Anne Barton; Sally John; Ian Bruce; Clive Hawkins; Christopher E M Griffiths; Rachelle Donn; Wendy Thomson; Alan Silman; Jane Worthington
Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: further support that PTPN22 is an autoimmunity gene.
Arthritis and rheumatism 2005;52(6):1694-9.
2005: Rebecca Lamb; Eleftheria Zeggini; Wendy Thomson; Rachelle Donn
Toll-like receptor 4 gene polymorphisms and susceptibility to juvenile idiopathic arthritis.
Annals of the rheumatic diseases 2005;64(5):767-9.
2005: Zaynab Alourfi; Rachelle Donn; Adam Stevens; A Berry; A McMaster; David W Ray
Glucocorticoids suppress macrophage migration inhibitory factor (MIF) expression in a cell-type-specific manner.
Journal of molecular endocrinology 2005;34(2):583-95.
2004: Adam Stevens; Rachelle Donn; David Ray
Regulation of glucocorticoid receptor gamma (GRgamma) by glucocorticoid receptor haplotype and glucocorticoid.
Clinical endocrinology 2004;61(3):327-31.
2004: Rachelle Donn; Darren Plant; Francine Jury; Helen L Richards; Jane Worthington; David W Ray; Christopher E M Griffiths
Macrophage migration inhibitory factor gene polymorphism is associated with psoriasis.
The Journal of investigative dermatology 2004;123(3):484-7.
2004: Eleftheria Zeggini; Anthony M Reginato; A Prais; W Thomson; William McLean; Rachelle Donn
Linkage and association studies of discoidin domain receptor 1 (DDR1) single nucleotide polymorphisms (SNPs) in juvenile oligoarthritis.
Rheumatology (Oxford, England) 2004;43(9):1138-41.
2004: Rachelle Donn; David W Ray
Macrophage migration inhibitory factor: molecular, cellular and genetic aspects of a key neuroendocrine molecule.
The Journal of endocrinology 2004;182(1):1-9.
2004: Rachelle Donn; Zaynab Alourfi; Eleftheria Zeggini; Rebecca Lamb; Francine Jury; Mark Lunt; Cristina Meazza; de benedetti fabrizio; Wendy Thomson; David Ray
A functional promoter haplotype of macrophage migration inhibitory factor is linked and associated with juvenile idiopathic arthritis.
Arthritis and rheumatism 2004;50(5):1604-10.
2004: Adam Stevens; David W Ray; Eleftheria Zeggini; Sally John; Helen L Richards; Christopher E M Griffiths; Rachelle Donn
Glucocorticoid sensitivity is determined by a specific glucocorticoid receptor haplotype.
The Journal of clinical endocrinology and metabolism 2004;89(2):892-7.
2003: Anne Barton; Rebecca Lamb; Deborah Symmons; A Silman; Wendy Thomson; Jane Worthington; Rachelle Donn
Macrophage migration inhibitory factor (MIF) gene polymorphism is associated with susceptibility to but not severity of inflammatory polyarthritis.
Genes and immunity 2003;4(7):487-91.
2003: R S Nicholas; J Partridge; Rachelle Donn; C Hawkins; Mike Boggild
The role of the PTPRC (CD45) mutation in the development of multiple sclerosis in the North West region of the United Kingdom.
Journal of neurology, neurosurgery, and psychiatry 2003;74(7):944-5.
2003: de benedetti fabrizio; Cristina Meazza; Marina Vivarelli; Federica Rossi; Angela Pistorio; Rebecca Lamb; Mark Lunt; Wendy Thomson; Angelo Ravelli; Rachelle Donn; Alberto Martini
Functional and prognostic relevance of the -173 polymorphism of the macrophage migration inhibitory factor gene in systemic-onset juvenile idiopathic arthritis.
Arthritis and rheumatism 2003;48(5):1398-407.
2002: Eleftheria Zeggini; Wendy Thomson; Dominic Kwiatkowski; Anna Richardson; W E R Ollier; Rachelle Donn
Linkage and association studies of single-nucleotide polymorphism-tagged tumor necrosis factor haplotypes in juvenile oligoarthritis.
Arthritis and rheumatism 2002;46(12):3304-11.
2002: Eleftheria Zeggini; Rachelle Donn; W E R Ollier; Wendy Thomson
Evidence for linkage of HLA loci in juvenile idiopathic oligoarthritis: independent effects of HLA-A and HLA-DRB1.
Arthritis and rheumatism 2002;46(10):2716-20.
2002: Wendy Thomson; JH Barrett; Rachelle Donn; L Pepper; Lorna J Kennedy; W E R Ollier; A J S Silman; Patricia Woo; T Southwood
Juvenile idiopathic arthritis classified by the ILAR criteria: HLA associations in UK patients.
Rheumatology (Oxford, England) 2002;41(10):1183-9.
2002: Rachelle Donn; Zaynab Alourfi; de benedetti fabrizio; Cristina Meazza; Eleftheria Zeggini; Mark Lunt; Adam Stevens; Emma Shelley; Rebecca Lamb; W E R Ollier; Wendy Thomson; David Ray
Mutation screening of the macrophage migration inhibitory factor gene: positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile idiopathic arthritis.
Arthritis and rheumatism 2002;46(9):2402-9.
2002: Mahsa M Amoli; Rachelle Donn; Wendy Thomson; Ali H Hajeer; Carlos Garcia-Porrua; Mercedes Lueiro; W E R Ollier; Miguel A Gonzalez-Gay
Macrophage migration inhibitory factor gene polymorphism is associated with sarcoidosis in biopsy proven erythema nodosum.
The Journal of rheumatology 2002;29(8):1671-3.
2002: Rachelle Donn; AJ Farhan; A Stevans; A Ramanan; W E R Ollier; Wendy Thomson
Neuroendocrine gene polymorphisms and susceptibility to juvenile idiopathic arthritis.
Rheumatology (Oxford, England) 2002;41(8):930-6.
2002: Eleftheria Zeggini; Wendy Thomson; Aliya Alansari; W E R Ollier; Rachelle Donn
Tumour necrosis factor receptor II polymorphism and juvenile idiopathic arthritis.
Rheumatology (Oxford, England) 2002;41(4):462-5.
2002: Wendy Thomson; Rachelle Donn
Juvenile idiopathic arthritis genetics - what's new? What's next?
Arthritis research 2002;4(5):302-6.
2002: Rachelle Donn; Eleftheria Zeggini; Emma Shelley; W E R Ollier; Wendy Thomson
Lack of association between juvenile idiopathic arthritis and fas gene polymorphism.
The Journal of rheumatology 2002;29(1):166-8.
2001: Adam Stevens; David Ray; Aliya Alansari; Ali Hajeer; Wendy Thomson; Rachelle Donn; W E R Ollier; Jane Worthington; J R Davis
Characterization of a prolactin gene polymorphism and its associations with systemic lupus erythematosus.
Arthritis and rheumatism 2001;44(10):2358-66.
2001: Rachelle Donn; Emma Shelley; W E R Ollier; Wendy Thomson
A novel 5'-flanking region polymorphism of macrophage migration inhibitory factor is associated with systemic-onset juvenile idiopathic arthritis.
Arthritis and rheumatism 2001;44(8):1782-5.
2001: S J M Weatherby; Wendy Thomson; L Pepper; Rachelle Donn; J Worthington; C L A Mann; MB Davies; Anthony A Fryer; Mike Boggild; C A Young; P W Jones; R C Strange; W E R Ollier; CP Hawkins
HLA-DRB1 and disease outcome in multiple sclerosis.
Journal of neurology 2001;248(4):304-10.
2001: Rachelle Donn; JH Barrett; AJ Farhan; A Stopford; L Pepper; Emma Shelley; N Davies; W E R Ollier; Wendy Thomson
Cytokine gene polymorphisms and susceptibility to juvenile idiopathic arthritis. British Paediatric Rheumatology Study Group.
Arthritis and rheumatism 2001;44(4):802-10.
2000: E Thomas; JH Barrett; Rachelle Donn; Wendy Thomson; T R Southwood
Subtyping of juvenile idiopathic arthritis using latent class analysis. British Paediatric Rheumatology Group.
Arthritis and rheumatism 2000;43(7):1496-503.
1999: C Pickard; C Mann; P Sinnott; Mike Boggild; C Hawkins; RC Strange; Ian Hutchinson; W E Ollier; Rachelle Donn
Interleukin-10 (IL10) promoter polymorphisms and multiple sclerosis.
Journal of neuroimmunology 1999;101(2):207-10.
1999: Rachelle Donn; AJ Farhan; JH Barrett; Wendy Thomson; Jane Worthington; W E R Ollier
Absence of association between interleukin 1 alpha and oligoarticular juvenile chronic arthritis in UK patients.
Rheumatology (Oxford, England) 1999;38(2):171-5.
1998: S John; D Turner; Rachelle Donn; PJ Sinnott; Jane Worthington; W E Ollier; Ian Hutchinson; Ali H Hajeer
Two novel biallelic polymorphisms in the IL-2 gene.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 1998;25(6):419-20.
1998: S J Stanworth; Rachelle Donn; A Hassall; P Dawes; W Ollier; N Snowden
Absence of an association between mannose-binding lectin polymorphism and rheumatoid arthritis.
British journal of rheumatology 1998;37(2):186-8.
1997: Emma J Davies; Lee-Suan Teh; Josep Ordi-Ros; N Snowden; M Chantal Hillarby; Ali Hajeer; Rachelle Donn; P Perez-Pemen; Miquel Vilardell-Tarres; W E R Ollier
A dysfunctional allele of the mannose binding protein gene associates with systemic lupus erythematosus in a Spanish population.
The Journal of rheumatology 1997;24(3):485-8.
1996: Rachelle Donn; W E R Ollier
Juvenile chronic arthritis--a time for change?
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 1996;23(3):245-60.
1996: M Chantal Hillarby; Emma J Davies; Rachelle Donn; D M Grennan; W E R Ollier
TAP2D is associated with HLA-B44 and DR4 and may contribute to rheumatoid arthritis and Felty's syndrome susceptibility.
Clinical and experimental rheumatology 1996;14(1):67-70.
1995: N Snowden; S Stanworth; Rachelle Donn; E Davies; B Ollier
Mannose-binding protein genotypes and recurrent infection.
Lancet 1995;346(8990):1629-31.
1995: Rachelle Donn; Wendy Thomson; L Pepper; D Carthy; A Farhan; C Ryder; T Southwood; L Holt; W E R Ollier
Antinuclear antibodies in early onset pauciarticular juvenile chronic arthritis (JCA) are associated with HLA-DQB1*0603: a possible JCA-associated human leucocyte antigen haplotype.
British journal of rheumatology 1995;34(5):461-5.
1995: A A Awomoyi; Rachelle Donn; Emma J Davies; D Carthy; Wendy Thomson; W E R Ollier
Absence of TAP 2D in Yoruba Nigerians.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 1995;22(2):187-90.
1995: D Carthy; A MacGregor; A Awomoi; A S Rigby; Wendy Thomson; Rachelle Donn; Alan Silman; W E R Ollier
HLA-DPB1*0201 is associated with particular clinical features of rheumatoid arthritis.
Revue du rhumatisme (English ed.) 1995;62(3):163-8.
1994: Rachelle Donn; Emma J Davies; Wendy Thomson; M Chantal Hillarby; W E R Ollier
Tap gene associations in UK caucasoids.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 1994;21(3):159-67.
1994: Rachelle Donn; Emma J Davies; P L Holt; Wendy Thomson; W E R Ollier
Increased frequency of TAP2B in early onset pauciarticular juvenile chronic arthritis.
Annals of the rheumatic diseases 1994;53(4):261-4.
1994: Emma J Davies; C J Hutchings; M Chantal Hillarby; Rachelle Donn; R G Cooper; E M Hay; R M Bernstein; P J L Holt; D M Grennan; W E R Ollier
HLA-DP does not contribute towards susceptibility to systemic lupus erythematosus.
Annals of the rheumatic diseases 1994;53(3):188-90.
1994: Emma J Davies; Rachelle Donn; M Chantal Hillarby; D M Grennan; W E R Ollier
Polymorphisms of the TAP2 transporter gene in systemic lupus erythematosus.
Annals of the rheumatic diseases 1994;53(1):61-3.
1993: G Dean; J A Hoyland; J Denton; Rachelle Donn; A J Freemont
Mast cells in the synovium and synovial fluid in osteoarthritis.
British journal of rheumatology 1993;32(8):671-5.
1991: Judith A Hoyland; J T Thomas; Rachelle Donn; A Marriott; S Ayad; Raymond P Boot-Handford; Michael E Grant; A J Freemont
Distribution of type X collagen mRNA in normal and osteoarthritic human cartilage.
Bone and mineral 1991;15(2):151-63.