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Arthur Donohue-Rolfe

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Emily M Mallick; Jean Mukherjee; Barbara J Sheppard; Saul Tzipori; Vijay K Vanguri; Michael J Brady; Arthur Donohue-Rolfe; John M Leong; Hui Liu; SA Luperchio; Loranne Magoun; David B Schauer
Allele- and tir-independent functions of intimin in diverse animal infection models.
Michael J Brady; Arthur Donohue-Rolfe; Hui Liu; Loranne Magoun; Jean Mukherjee; Kenan C Murphy; Padhma Radhakrishnan; Saul Tzipori; John M Leong
Enhanced Actin Pedestal Formation by Enterohemorrhagic Escherichia coli O157:H7 Adapted to the Mammalian Host.
Rembert Pieper; Quanshun Zhang; Prashanth P Parmar; Shih-Ting Huang; David J Clark; Hamid Alami; Arthur Donohue-Rolfe; Robert D Fleischmann; Scott N Peterson; Saul Tzipori
The Shigella dysenteriae serotype 1 proteome, profiled in the host intestinal environment, reveals major metabolic modifications and increased expression of invasive proteins.

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2012: Emily M Mallick; Jean Mukherjee; Barbara J Sheppard; Saul Tzipori; Vijay K Vanguri; Michael J Brady; Arthur Donohue-Rolfe; John M Leong; Hui Liu; SA Luperchio; Loranne Magoun; David B Schauer
Allele- and tir-independent functions of intimin in diverse animal infection models.
Frontiers in microbiology 2012;3():11.
2011: Michael J Brady; Arthur Donohue-Rolfe; Hui Liu; Loranne Magoun; Jean Mukherjee; Kenan C Murphy; Padhma Radhakrishnan; Saul Tzipori; John M Leong
Enhanced Actin Pedestal Formation by Enterohemorrhagic Escherichia coli O157:H7 Adapted to the Mammalian Host.
Frontiers in microbiology 2011;2():226.
2009: Rembert Pieper; Quanshun Zhang; Prashanth P Parmar; Shih-Ting Huang; David J Clark; Hamid Alami; Arthur Donohue-Rolfe; Robert D Fleischmann; Scott N Peterson; Saul Tzipori
The Shigella dysenteriae serotype 1 proteome, profiled in the host intestinal environment, reveals major metabolic modifications and increased expression of invasive proteins.
Proteomics 2009;9(22):5029-45.
2009: Quanshun Zhang; Arthur Donohue-Rolfe; Greice Krautz-Peterson; Milica Sevo; Nicola Parry; Claudia Abeijon; Saul Tzipori
Gnotobiotic piglet infection model for evaluating the safe use of antibiotics against Escherichia coli O157:H7 infection.
The Journal of infectious diseases 2009;199(4):486-93.
2009: Srilatha Kuntumalla; John C Braisted; Shih-Ting Huang; Prashanth P Parmar; David J Clark; Hamid Alami; Quanshun Zhang; Arthur Donohue-Rolfe; Saul Tzipori; Robert D Fleischmann; Scott N Peterson; Rembert Pieper
Comparison of two label-free global quantitation methods, APEX and 2D gel electrophoresis, applied to the Shigella dysenteriae proteome.
Proteome science 2009;7():22.
2008: Jennifer M Ritchie; Michael J Brady; Kathleen N Riley; Theresa Deland Ho; Kenneth G Campellone; Ira M Herman; Arthur Donohue-Rolfe; Saul Tzipori; Matthew K Waldor; John M Leong
EspFU, a type III-translocated effector of actin assembly, fosters epithelial association and late-stage intestinal colonization by E. coli O157:H7.
Cellular microbiology 2008;10(4):836-47.
2007: Kenneth G Campellone; Andrew J Roe; Anders Løbner-Olesen; Kenan C Murphy; Loranne Magoun; Michael J Brady; Arthur Donohue-Rolfe; Saul Tzipori; David L Gally; John M Leong; Martin G Marinus
Increased adherence and actin pedestal formation by dam-deficient enterohaemorrhagic Escherichia coli O157:H7.
Molecular microbiology 2007;63(5):1468-81.
2005: Abhineet S Sheoran; Susan Chapman-Bonofiglio; Barrett R Harvey; Jean Mukherjee; george Georgiou; Arthur Donohue-Rolfe; Saul Tzipori
Human antibody against shiga toxin 2 administered to piglets after the onset of diarrhea due to Escherichia coli O157:H7 prevents fatal systemic complications.
Infection and immunity 2005;73(8):4607-13.
2005: Donna E Akiyoshi; C M Rich; S O'Sullivan-Murphy; L Richard; J Dilo; Arthur Donohue-Rolfe; Abhineet S Sheoran; Susan Chapman-Bonofiglio; Saul Tzipori
Characterization of a human monoclonal antibody against Shiga toxin 2 expressed in Chinese hamster ovary cells.
Infection and immunity 2005;73(7):4054-61.
2004: Saul Tzipori; Abhineet S Sheoran; Donna E Akiyoshi; Arthur Donohue-Rolfe; Howard Trachtman
Antibody therapy in the management of shiga toxin-induced hemolytic uremic syndrome.
Clinical microbiology reviews 2004;17(4):926-41, table of contents.
2003: Abhineet S Sheoran; Susan Chapman; Pradeep Singh; Arthur Donohue-Rolfe; Saul Tzipori
Stx2-specific human monoclonal antibodies protect mice against lethal infection with Escherichia coli expressing Stx2 variants.
Infection and immunity 2003;71(6):3125-30.
2002: Jean Mukherjee; Kerry Chios; Dianne Fishwild; Deborah Hudson; Susan O'Donnell; Stephen M Rich; Arthur Donohue-Rolfe; Saul Tzipori
Production and characterization of protective human antibodies against Shiga toxin 1.
Infection and immunity 2002;70(10):5896-9.
2002: Jean Mukherjee; Kerry Chios; Dianne Fishwild; Deborah Hudson; Susan O'Donnell; Stephen M Rich; Arthur Donohue-Rolfe; Saul Tzipori
Human Stx2-specific monoclonal antibodies prevent systemic complications of Escherichia coli O157:H7 infection.
Infection and immunity 2002;70(2):612-9.
2000: Arthur Donohue-Rolfe; II Kondova; S Oswald; D Hutto; Saul Tzipori
Escherichia coli O157:H7 strains that express Shiga toxin (Stx) 2 alone are more neurotropic for gnotobiotic piglets than are isotypes producing only Stx1 or both Stx1 and Stx2.
The Journal of infectious diseases 2000;181(5):1825-9.
1999: Arthur Donohue-Rolfe; II Kondova; Jean Mukherjee; Kerry Chios; D Hutto; Saul Tzipori
Antibody-based protection of gnotobiotic piglets infected with Escherichia coli O157:H7 against systemic complications associated with Shiga toxin 2.
Infection and immunity 1999;67(7):3645-8.
1999: S Fuchs; I Mühldorfer; Arthur Donohue-Rolfe; Monika Kerényi; Levente Emödy; R Alexiev; P Nenkov; Jörg Hacker
Influence of RecA on in vivo virulence and Shiga toxin 2 production in Escherichia coli pathogens.
Microbial pathogenesis 1999;27(1):13-23.
1998: Florian Gunzer; U Bohn; S Fuchs; I Mühldorfer; Jörg Hacker; Saul Tzipori; Arthur Donohue-Rolfe
Construction and characterization of an isogenic slt-ii deletion mutant of enterohemorrhagic Escherichia coli.
Infection and immunity 1998;66(5):2337-41.
1996: I Mühldorfer; G Blum; Arthur Donohue-Rolfe; H Heier; T Olschläger; Helmut Tschäpe; U Wallner; Jörg Hacker
Characterization of Escherichia coli strains isolated from environmental water habitats and from stool samples of healthy volunteers.
Research in microbiology 1996;147(8):625-35.
1996: I Mühldorfer; Jörg Hacker; Gerald T Keusch; David W K Acheson; Helmut Tschäpe; Anne Kane; A Ritter; T Olschläger; Arthur Donohue-Rolfe
Regulation of the Shiga-like toxin II operon in Escherichia coli.
Infection and immunity 1996;64(2):495-502.
1996: Vince Pozsgay; Loc Ba Trinh; Joseph Shiloach; John B Robbins; Arthur Donohue-Rolfe; Stephen B Calderwood
Purification of subunit B of Shiga toxin using a synthetic trisaccharide-based affinity matrix.
Bioconjugate chemistry 1996;7(1):45-55.
1995: MS Jacewicz; David W K Acheson; M Mobassaleh; Arthur Donohue-Rolfe; K A Balasubramanian; Gerald T Keusch
Maturational regulation of globotriaosylceramide, the Shiga-like toxin 1 receptor, in cultured human gut epithelial cells.
The Journal of clinical investigation 1995;96(3):1328-35.
1995: Saul Tzipori; Florian Gunzer; Michael S Donnenberg; L de Montigny; James B Kaper; Arthur Donohue-Rolfe
The role of the eaeA gene in diarrhea and neurological complications in a gnotobiotic piglet model of enterohemorrhagic Escherichia coli infection.
Infection and immunity 1995;63(9):3621-7.
1995: Gerald T Keusch; MS Jacewicz; David W K Acheson; Arthur Donohue-Rolfe; Anne Kane; R H McCluer
Globotriaosylceramide, Gb3, is an alternative functional receptor for Shiga-like toxin 2e.
Infection and immunity 1995;63(3):1138-41.
1995: David W K Acheson; S A De Breucker; MS Jacewicz; L L Lincicome; Arthur Donohue-Rolfe; Anne Kane; Gerald T Keusch
Expression and purification of Shiga-like toxin II B subunits.
Infection and immunity 1995;63(1):301-8.
1993: A E Hull; David W K Acheson; P Echeverria; Arthur Donohue-Rolfe; Gerald T Keusch
Mitomycin immunoblot colony assay for detection of Shiga-like toxin-producing Escherichia coli in fecal samples: comparison with DNA probes.
Journal of clinical microbiology 1993;31(5):1167-72.
1993: David W K Acheson; Stephen B Calderwood; S A Boyko; L L Lincicome; Anne Kane; Arthur Donohue-Rolfe; Gerald T Keusch
Comparison of Shiga-like toxin I B-subunit expression and localization in Escherichia coli and Vibrio cholerae by using trc or iron-regulated promoter systems.
Infection and immunity 1993;61(3):1098-104.
1993: David W K Acheson; MS Jacewicz; Anne Kane; Arthur Donohue-Rolfe; Gerald T Keusch
One step high yield affinity purification of shiga-like toxin II variants and quantitation using enzyme linked immunosorbent assays.
Microbial pathogenesis 1993;14(1):57-66.
1992: Myron M Levine; J McEwen; Genevieve A Losonsky; M Reymann; I Harari; John Brown; David N Taylor; Arthur Donohue-Rolfe; D Cohen; Michael Bennish
Antibodies to shiga holotoxin and to two synthetic peptides of the B subunit in sera of patients with Shigella dysenteriae 1 dysentery.
Journal of clinical microbiology 1992;30(7):1636-41.
1992: D Law; L A Ganguli; Arthur Donohue-Rolfe; David W K Acheson
Detection by ELISA of low numbers of Shiga-like toxin-producing Escherichia coli in mixed cultures after growth in the presence of mitomycin C.
Journal of medical microbiology 1992;36(3):198-202.
1991: Peter Hart; Arthur F Monzingo; Arthur Donohue-Rolfe; G T Keusch; Stephen B Calderwood; Jon D Robertus
Crystallization of the B chain of Shiga-like toxin I from Escherichia coli.
Journal of molecular biology 1991;218(4):691-4.
1991: Gerald T Keusch; MS Jacewicz; M Mobassaleh; Arthur Donohue-Rolfe
Shiga toxin: intestinal cell receptors and pathophysiology of enterotoxic effects.
Reviews of infectious diseases 1991;13 Suppl 4():S304-10.
1991: Arthur Donohue-Rolfe; David W K Acheson; Gerald T Keusch
Shiga toxin: purification, structure, and function.
Reviews of infectious diseases 1991;13 Suppl 4():S293-7.
1990: Stephen B Calderwood; David W K Acheson; M B Goldberg; S A Boyko; Arthur Donohue-Rolfe
A system for production and rapid purification of large amounts of the Shiga toxin/Shiga-like toxin I B subunit.
Infection and immunity 1990;58(9):2977-82.
1990: Michael S Donnenberg; Stephen B Calderwood; Arthur Donohue-Rolfe; G T Keusch; James B Kaper
Construction and analysis of TnphoA mutants of enteropathogenic Escherichia coli unable to invade HEp-2 cells.
Infection and immunity 1990;58(6):1565-71.
1990: Michael S Donnenberg; Arthur Donohue-Rolfe; G T Keusch
A comparison of HEp-2 cell invasion by enteropathogenic and enteroinvasive Escherichia coli.
FEMS microbiology letters 1990;57(1-2):83-6.
1990: David W K Acheson; Gerald T Keusch; M Lightowlers; Arthur Donohue-Rolfe
Enzyme-linked immunosorbent assay for Shiga toxin and Shiga-like toxin II using P1 glycoprotein from hydatid cysts.
The Journal of infectious diseases 1990;161(1):134-7.
1989: Arthur Donohue-Rolfe; David W K Acheson; Anne Kane; Gerald T Keusch
Purification of Shiga toxin and Shiga-like toxins I and II by receptor analog affinity chromatography with immobilized P1 glycoprotein and production of cross-reactive monoclonal antibodies.
Infection and immunity 1989;57(12):3888-93.
1989: David W K Acheson; Arthur Donohue-Rolfe
Cancer-associated hemolytic uremic syndrome: a possible role of mitomycin in relation to Shiga-like toxins.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989;7(12):1943.
1989: G Kandel; Arthur Donohue-Rolfe; Mark Donowitz; Gerald T Keusch
Pathogenesis of Shigella diarrhea. XVI. Selective targetting of Shiga toxin to villus cells of rabbit jejunum explains the effect of the toxin on intestinal electrolyte transport.
The Journal of clinical investigation 1989;84(5):1509-17.
1989: Arthur Donohue-Rolfe; MS Jacewicz; Gerald T Keusch
Isolation and characterization of functional Shiga toxin subunits and renatured holotoxin.
Molecular microbiology 1989;3(9):1231-6.
1989: Michael S Donnenberg; Arthur Donohue-Rolfe; Gerald T Keusch
Epithelial cell invasion: an overlooked property of enteropathogenic Escherichia coli (EPEC) associated with the EPEC adherence factor.
The Journal of infectious diseases 1989;160(3):452-9.
1989: M Mobassaleh; S K Gross; R H McCluer; Arthur Donohue-Rolfe; Gerald T Keusch
Quantitation of the rabbit intestinal glycolipid receptor for Shiga toxin. Further evidence for the developmental regulation of globotriaosylceramide in microvillus membranes.
Gastroenterology 1989;97(2):384-91.
1989: MS Jacewicz; H A Feldman; Arthur Donohue-Rolfe; K A Balasubramanian; Gerald T Keusch
Pathogenesis of Shigella diarrhea. XIV. Analysis of Shiga toxin receptors on cloned HeLa cells.
The Journal of infectious diseases 1989;159(5):881-9.
1988: I Harari; Arthur Donohue-Rolfe; G Keusch; Ruth Arnon
Synthetic peptides of Shiga toxin B subunit induce antibodies which neutralize its biological activity.
Infection and immunity 1988;56(6):1618-24.
1988: M Mobassaleh; Arthur Donohue-Rolfe; MS Jacewicz; Richard J Grand; Gerald T Keusch
Pathogenesis of shigella diarrhea: evidence for a developmentally regulated glycolipid receptor for shigella toxin involved in the fluid secretory response of rabbit small intestine.
The Journal of infectious diseases 1988;157(5):1023-31.
1988: Gerald T Keusch; Arthur Donohue-Rolfe; MS Jacewicz; Anne Kane
Shiga toxin: production and purification.
Methods in enzymology 1988;165():152-62, 399-401.
1988: Arthur Donohue-Rolfe; MS Jacewicz; Gerald T Keusch
Shiga toxin as inhibitor of protein synthesis.
Methods in enzymology 1988;165():231-5.
1987: Stephen B Calderwood; F Auclair; Arthur Donohue-Rolfe; G T Keusch; J J Mekalanos
Nucleotide sequence of the Shiga-like toxin genes of Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(13):4364-8.
1986: N G Seidah; Arthur Donohue-Rolfe; C Lazure; F Auclair; G T Keusch; M Chrétien
Complete amino acid sequence of Shigella toxin B-chain. A novel polypeptide containing 69 amino acids and one disulfide bridge.
The Journal of biological chemistry 1986;261(30):13928-31.
1986: G Fuchs; M Mobassaleh; Arthur Donohue-Rolfe; Robert K Montgomery; Richard J Grand; Gerald T Keusch
Pathogenesis of Shigella diarrhea: rabbit intestinal cell microvillus membrane binding site for Shigella toxin.
Infection and immunity 1986;53(2):372-7.
1986: Arthur Donohue-Rolfe; M A Kelley; Michael Bennish; G T Keusch
Enzyme-linked immunosorbent assay for shigella toxin.
Journal of clinical microbiology 1986;24(1):65-8.
1986: MS Jacewicz; H Clausen; E Nudelman; Arthur Donohue-Rolfe; Gerald T Keusch
Pathogenesis of shigella diarrhea. XI. Isolation of a shigella toxin-binding glycolipid from rabbit jejunum and HeLa cells and its identification as globotriaosylceramide.
The Journal of experimental medicine 1986;163(6):1391-404.
1986: Gerald T Keusch; MS Jacewicz; Arthur Donohue-Rolfe
Pathogenesis of shigella diarrhea: evidence for an N-linked glycoprotein shigella toxin receptor and receptor modulation by beta-galactosidase.
The Journal of infectious diseases 1986;153(2):238-48.
1986: I Harari; Arthur Donohue-Rolfe; G T Keusch; Ruth Arnon
Synthetic peptides of Shiga toxin B-subunit induce antibodies which neutralize the biological activities of the toxin.
Annali Sclavo. Collana monografica 1986;3(1-2):125-30.
1985: Gerald T Keusch; Arthur Donohue-Rolfe; MS Jacewicz
Shigella toxin and the pathogenesis of shigellosis.
Ciba Foundation symposium 1985;112():193-214.
1984: Arthur Donohue-Rolfe; Gerald T Keusch; C Edson; D Thorley-Lawson; MS Jacewicz
Pathogenesis of Shigella diarrhea. IX. Simplified high yield purification of Shigella toxin and characterization of subunit composition and function by the use of subunit-specific monoclonal and polyclonal antibodies.
The Journal of experimental medicine 1984;160(6):1767-81.
1981: Gerald T Keusch; Arthur Donohue-Rolfe; MS Jacewicz
Shigella toxin(s): description and role in diarrhea and dysentery.
Pharmacology & therapeutics 1981;15(3):403-38.