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David Donovan

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Jinzhe Mao; Mathias Schmelcher; Juli Foster-Frey; William J Harty; David M Donovan
Chimeric Ply187 endolysin kills Staphylococcus aureus more effectively than the parental enzyme.
Igor Abaev; Stephen C Becker; Juli Foster-Frey; Natalia Kiseleva; Pavel Kopylov; OV Korobova; Sergey Pryamchuk; Mathias Schmelcher; Nina Shishkova; David M Donovan
Staphylococcal phage 2638A endolysin is lytic for Staphylococcus aureus and harbors an inter-lytic-domain secondary translational start site.
Dwayne R Roach; Kenneth M Bischoff; Stephen R Hughes; Piyum A Khatibi; David M Donovan
Bacteriophage-encoded lytic enzymes control growth of contaminating Lactobacillus found in fuel ethanol fermentations.

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All Publications

2013: Jinzhe Mao; Mathias Schmelcher; Juli Foster-Frey; William J Harty; David M Donovan
Chimeric Ply187 endolysin kills Staphylococcus aureus more effectively than the parental enzyme.
FEMS microbiology letters 2013;342(1):30-6.
2013: Igor Abaev; Stephen C Becker; Juli Foster-Frey; Natalia Kiseleva; Pavel Kopylov; OV Korobova; Sergey Pryamchuk; Mathias Schmelcher; Nina Shishkova; David M Donovan
Staphylococcal phage 2638A endolysin is lytic for Staphylococcus aureus and harbors an inter-lytic-domain secondary translational start site.
Applied microbiology and biotechnology 2013;97(8):3449-56.
2013: Dwayne R Roach; Kenneth M Bischoff; Stephen R Hughes; Piyum A Khatibi; David M Donovan
Bacteriophage-encoded lytic enzymes control growth of contaminating Lactobacillus found in fuel ethanol fermentations.
Biotechnology for biofuels 2013;6(1):20.
2012: Mathias Schmelcher; David M Donovan; Natalia Kiseleva; Paul Kopylov; Olga Korobova; Sergey Pryamchuk; Nina Schischkova; Igor Abaev
Staphylococcus haemolyticus prophage ΦSH2 endolysin relies on cysteine, histidine-dependent amidohydrolases/peptidases activity for lysis 'from without'.
Journal of biotechnology 2012;162(2-3):289-98.
2010: Theresa A Kopajtic; Yi Liu; Christopher K Surratt; David M Donovan; Amy Hauck Newman; Jonathan L Katz
Dopamine transporter-dependent and -independent striatal binding of the benztropine analog JHW 007, a cocaine antagonist with low abuse liability.
The Journal of pharmacology and experimental therapeutics 2010;335(3):703-14.
2009: Stephen C Becker; Juli Foster-Frey; Angeline J Stodola; Daniel Anacker; David M Donovan
Differentially conserved staphylococcal SH3b_5 cell wall binding domains confer increased staphylolytic and streptolytic activity to a streptococcal prophage endolysin domain.
Gene 2009;443(1-2):32-41.
2009: Stephen C Becker; Shengli Dong; John R Baker; Juli Foster-Frey; David G Pritchard; David M Donovan
LysK CHAP endopeptidase domain is required for lysis of live staphylococcal cells.
FEMS microbiology letters 2009;294(1):52-60.
2008: Stephen C Becker; Juli Foster-Frey; David M Donovan
The phage K lytic enzyme LysK and lysostaphin act synergistically to kill MRSA.
FEMS microbiology letters 2008;287(2):185-91.
2008: David M Donovan; Juli Foster-Frey
LambdaSa2 prophage endolysin requires Cpl-7-binding domains and amidase-5 domain for antimicrobial lysis of streptococci.
FEMS microbiology letters 2008;287(1):22-33.
2008: David M Donovan; Juli Foster-Frey; Wesley M Garrett; Le Ann Blomberg
Resolving the database sequence discrepancies for the Staphylococcus aureus bacteriophage phi 11 amidase.
Journal of basic microbiology 2008;48(1):48-52.
2006: David M Donovan; Michelle Lardeo; Juli Foster-Frey
Lysis of staphylococcal mastitis pathogens by bacteriophage phi11 endolysin.
FEMS microbiology letters 2006;265(1):133-9.
2006: David M Donovan; Juli Foster-Frey; Shengli Dong; Geneviève M Rousseau; Sylvain Moineau; David G Pritchard
The cell lysis activity of the Streptococcus agalactiae bacteriophage B30 endolysin relies on the cysteine, histidine-dependent amidohydrolase/peptidase domain.
Applied and environmental microbiology 2006;72(7):5108-12.
2006: David M Donovan; Shengli Dong; Wes Garrett; Geneviève M Rousseau; Sylvain Moineau; David G Pritchard
Peptidoglycan hydrolase fusions maintain their parental specificities.
Applied and environmental microbiology 2006;72(4):2988-96.
2005: David M Donovan; David E Kerr; Robert J Wall
Engineering disease resistant cattle.
Transgenic research 2005;14(5):563-7.
2005: HD Guthrie; Robert J Wall; Vernon Pursel; Juli Foster-Frey; David M Donovan; Harry Dawson; Glenn Welch; W G Garrett
Follicular expression of a human beta-cell leukaemia/lymphoma-2 (Bcl-2) transgene does not decrease atresia or increase ovulation rate in swine.
Reproduction, fertility, and development 2005;17(4):457-66.
2004: Tao Xie; Liqiong Tong; Una D McCann; Jie Yuan; Kevin G Becker; Annis Mechan; Chris Cheadle; David M Donovan; George A Ricaurte
Identification and characterization of metallothionein-1 and -2 gene expression in the context of (+/-)3,4-methylenedioxymethamphetamine-induced toxicity to brain dopaminergic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(32):7043-50.
2004: David M Donovan; Daniel L Rowley; Nancy G Williams
Microsoft Excel spreadsheet-based animal colony management for genetically altered animals.
BioTechniques 2004;37(1):50, 52, 54 passim.
2003: Cheng-Shui Zhao; YUANXIANG TAO; Jill M Tall; David M Donovan; Richard A Meyer; Srinivasa N Raja
Role of micro-opioid receptors in formalin-induced pain behavior in mice.
Experimental neurology 2003;184(2):839-45.
2002: David M Donovan; Kevin G Becker
Double round hybridization of membrane based cDNA arrays: improved background reduction and data replication.
Journal of neuroscience methods 2002;118(1):59-62.
2002: Li Zhou; Virginie Népote; Daniel L Rowley; Béatrice Levacher; Agnes Zvara; Miklos Santha; Quing Sheng Mi; Michel Simonneau; David M Donovan
Murine peripherin gene sequences direct Cre recombinase expression to peripheral neurons in transgenic mice.
FEBS letters 2002;523(1-3):68-72.
2002: Richard B Rothman; Frank carroll; Marisela Morales; Daniel L Rowley; Kenner C Rice; Christina M Dersch; David M Donovan
Studies of the biogenic amine transporters. 10. Characterization of a novel cocaine binding site in brain membranes prepared from dopamine transporter knockout mice.
Synapse (New York, N.Y.) 2002;44(2):94-105.
2002: Heikki Mansikka; Li Zhou; David M Donovan; Antti Pertovaara; Srinivasa N Raja
The role of mu-opioid receptors in inflammatory hyperalgesia and alpha 2-adrenoceptor-mediated antihyperalgesia.
Neuroscience 2002;113(2):339-49.
2002: Tao Xie; Liqiong Tong; Tanya Barrett; Jie Yuan; George Hatzidimitriou; Una D McCann; Kevin G Becker; David M Donovan; George A Ricaurte
Changes in gene expression linked to methamphetamine-induced dopaminergic neurotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(1):274-83.
2001: Li Zhou; Daniel L Rowley; Quing Sheng Mi; N Sefcovic; H W Matthes; B L Kieffer; David M Donovan
Murine inter-strain polymorphisms alter gene targeting frequencies at the mu opioid receptor locus in embryonic stem cells.
Mammalian genome : official journal of the International Mammalian Genome Society 2001;12(10):772-8.
2001: Tanya Barrett; Tao Xie; Yulan Piao; Ora Dillon-Carter; George John Kargul; MK Lim; Francis J Chrest; Robert P Wersto; Daniel L Rowley; Magdalena Juhaszova; Li Zhou; Marquis P Vawter; Kevin G Becker; Chris Cheadle; William H Wood; Una D McCann; William J Freed; Minoru S H Ko; George A Ricaurte; David M Donovan
A murine dopamine neuron-specific cDNA library and microarray: increased COX1 expression during methamphetamine neurotoxicity.
Neurobiology of disease 2001;8(5):822-33.
2001: Marquis P Vawter; Tanya Barrett; Chris Cheadle; Boris P Sokolov; William H Wood; David M Donovan; M Webster; William J Freed; Kevin G Becker
Application of cDNA microarrays to examine gene expression differences in schizophrenia.
Brain research bulletin 2001;55(5):641-50.
2001: Tanya Barrett; Chris Cheadle; W B Wood; Diane Teichberg; David M Donovan; William J Freed; Kevin G Becker; Marquis P Vawter
Assembly and use of a broadly applicable neural cDNA microarray.
Restorative neurology and neuroscience 2001;18(2-3):127-35.
2001: Mary E Truckenmiller; Marquis P Vawter; Chris Cheadle; Mark Coggiano; David M Donovan; William J Freed; Kevin G Becker
Gene expression profile in early stage of retinoic acid-induced differentiation of human SH-SY5Y neuroblastoma cells.
Restorative neurology and neuroscience 2001;18(2-3):67-80.
2000: Quing Sheng Mi; Li Zhou; Dan H Schulze; RT Fischer; Ana Lustig; Louis J Rezanka; David M Donovan; Dan Longo; James J Kenny
Highly reduced protection against Streptococcus pneumoniae after deletion of a single heavy chain gene in mouse.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):6031-6.
2000: Mark D Duncan; Tarik Tihan; David M Donovan; Quy H Phung; Daniel L Rowley; John W Harmon; Patricia J Gearhart; KIMBERLY DUNCAN
Esophagogastric adenocarcinoma in an E1A/E1B transgenic model involves p53 disruption.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2000;4(3):290-7.
1999: David M Donovan; LL Miner; M P Perry; RS Revay; Lawrence G Sharpe; Serge Przedborski; V Kostic; Rex Philpot; Cheryl L Kirstein; Richard B Rothman; Charles W Schindler; George R. Uhl
Cocaine reward and MPTP toxicity: alteration by regional variant dopamine transporter overexpression.
Brain research. Molecular brain research 1999;73(1-2):37-49.
1997: Ichiro Sora; N Takahashi; M Funada; H Ujike; RS Revay; David M Donovan; LL Miner; George R. Uhl
Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(4):1544-9.
1996: David M Donovan; LL Miner; L Sharpe; H J Cho; M Takemura; Ellen M Unterwald; F Nyberg; M J Kreek; George R. Uhl
Transgenic mice: preproenkephalin and the mu opiate receptor.
Annals of the New York Academy of Sciences 1996;780():19-28.
1995: David M Donovan; D J Vandenbergh; M P Perry; G S Bird; R Ingersoll; E Nanthakumar; George R. Uhl
Human and mouse dopamine transporter genes: conservation of 5'-flanking sequence elements and gene structures.
Brain research. Molecular brain research 1995;30(2):327-35.
1994: B F O'Hara; David M Donovan; Iris Lindberg; M T Brannock; D D Ricker; C A Moffatt; B A Klaunberg; C Schindler; T S Chang; R J Nelson
Proenkephalin transgenic mice: a short promoter confers high testis expression and reduced fertility.
Molecular reproduction and development 1994;38(3):275-84.
1992: S Kitayama; S Shimada; Heng Xu; L Markham; David M Donovan; George R. Uhl
Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7782-5.
1992: M Takemura; David M Donovan; George R. Uhl
Primary afferent stimulation acts through a 193 base pair promoter region to upregulate preproenkephalin expression in dorsal horn of transgenic mice.
Brain research. Molecular brain research 1992;13(3):207-12.
1992: David M Donovan; M Takemura; B F O'Hara; M T Brannock; George R. Uhl
Preproenkephalin promoter "cassette" confers brain expression and synaptic regulation in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(6):2345-9.
1991: Garry R Cutting; L Lu; B F O'Hara; L M Kasch; C Montrose-Rafizadeh; David M Donovan; S Shimada; S E Antonarakis; William B Guggino; George R. Uhl
Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(7):2673-7.