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Jennifer Donovan

Research Profile

Chemicals & Drugs

Procedures

Physiology

Drug Interactions

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Cacao
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Publications

TOP 3
Katherine M Carey; Morgan R Comee; Jennifer L Donovan; Abir O Kanaan
A polypill for all? Critical review of the polypill literature for primary prevention of cardiovascular disease and stroke.
Niyati H Vakil; Abir O Kanaan; Jennifer L Donovan
Heparin-induced thrombocytopenia in the pediatric population: a review of current literature.
Abir O Kanaan; Jayne E Lepage; Shabdis Djazayeri; Jennifer L Donovan
Evaluating the Role of Compression Stockings in Preventing Post thrombotic Syndrome: A Review of the Literature.

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All Publications

2012: Katherine M Carey; Morgan R Comee; Jennifer L Donovan; Abir O Kanaan
A polypill for all? Critical review of the polypill literature for primary prevention of cardiovascular disease and stroke.
The Annals of pharmacotherapy 2012;46(5):688-95.
2012: Niyati H Vakil; Abir O Kanaan; Jennifer L Donovan
Heparin-induced thrombocytopenia in the pediatric population: a review of current literature.
The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG 2012;17(1):12-30.
2012: Abir O Kanaan; Jayne E Lepage; Shabdis Djazayeri; Jennifer L Donovan
Evaluating the Role of Compression Stockings in Preventing Post thrombotic Syndrome: A Review of the Literature.
Thrombosis 2012;2012():694851.
2012: Aimon C Miranda; Maichi T Tran; Jennifer L Donovan; Joel M Gore
A case of unsuccessful treatment of heparin-induced thrombocytopenia (HIT) with fondaparinux.
Journal of thrombosis and thrombolysis 2012;33(1):133-5.
2010: Alejandra M Pacchioni; Amanda Gabriele; Jennifer L Donovan; C Lindsay DeVane; Ronald E See
P-glycoprotein inhibition potentiates the behavioural and neurochemical actions of risperidone in rats.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2010;13(8):1067-77.
2010: Paul B Shaw; Jennifer L Donovan; Maichi T Tran; Stephenie C Lemon; Pamela Burgwinkle; Joel Gore
Accuracy assessment of pharmacogenetically predictive warfarin dosing algorithms in patients of an academic medical center anticoagulation clinic.
Journal of thrombosis and thrombolysis 2010;30(2):220-5.
2010: Jennifer L Donovan; Maichi T Tran; Abir O Kanaan
An overview of heparin-induced thrombocytopenia.
Journal of pharmacy practice 2010;23(3):226-34.
2010: Brent M Egan; Marilyn A Laken; Jennifer L Donovan; Robert F Woolson
Does dark chocolate have a role in the prevention and management of hypertension?: commentary on the evidence.
Hypertension 2010;55(6):1289-95.
2009: William Mullen; Gina Borges; Jennifer L Donovan; Christine A Edwards; Mauro Serafini; M E J Lean; Alan Crozier
Milk decreases urinary excretion but not plasma pharmacokinetics of cocoa flavan-3-ol metabolites in humans.
The American journal of clinical nutrition 2009;89(6):1784-91.
2009: Jun-Sheng Wang; Hao-Jie Zhu; Jennifer L Donovan; Hong-Jie Yuan; John S Markowitz; Mark E Geesey; C Lindsay DeVane
Aripiprazole brain concentration is altered in P-glycoprotein deficient mice.
Schizophrenia research 2009;110(1-3):90-4.
2008: Jun-Sheng Wang; Hao-Jie Zhu; John S Markowitz; Jennifer L Donovan; Hong-Jie Yuan; C Lindsay DeVane
Antipsychotic drugs inhibit the function of breast cancer resistance protein.
Basic & clinical pharmacology & toxicology 2008;103(4):336-41.
2008: John S Markowitz; Lisa L Von Moltke; Jennifer L Donovan
Predicting interactions between conventional medications and botanical products on the basis of in vitro investigations.
Molecular nutrition & food research 2008;52(7):747-54.
2008: Hao-Jie Zhu; Kennerly S Patrick; Hong-Jie Yuan; Jun-Sheng Wang; Jennifer L Donovan; C Lindsay DeVane; Robert Malcolm; Julie A Johnson; Geri L Youngblood; Douglas H Sweet; Taimour Y Langaee; Hao-Jie Zhu
Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis.
American journal of human genetics 2008;82(6):1241-8.
2008: Jun-Sheng Wang; Hao-Jie Zhu; Bryan B Gibson; Hao-Jie Zhu; Jennifer L Donovan; C Lindsay DeVane
Sertraline and its metabolite desmethylsertraline, but not bupropion or its three major metabolites, have high affinity for P-glycoprotein.
Biological & pharmaceutical bulletin 2008;31(2):231-4.
2008: Hao-Jie Zhu; Jun-Sheng Wang; Jennifer L Donovan; Yan Jiang; Bryan B Gibson; C Lindsay DeVane; Hao-Jie Zhu
Interactions of attention-deficit/hyperactivity disorder therapeutic agents with the efflux transporter P-glycoprotein.
European journal of pharmacology 2008;578(2-3):148-58.
2008: Karen A Cooper; Jennifer L Donovan; Andrew L Waterhouse; Gary Williamson
Cocoa and health: a decade of research.
The British journal of nutrition 2008;99(1):1-11.
2007: Melissa A Miller; Marisela Navarro; Steven Bird; Jennifer L Donovan
Antiemetic use in acetaminophen poisoning: how does the route of N-acetylcysteine administration affect utilization?
Journal of medical toxicology : official journal of the American College of Medical Toxicology 2007;3(4):152-6.
2007: Hao-Jie Zhu; Jun-Sheng Wang; Kennerly S Patrick; Jennifer L Donovan; C Lindsay DeVane; Hao-Jie Zhu
A novel HPLC fluorescence method for the quantification of methylphenidate in human plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;858(1-2):91-5.
2007: D Jeffrey Newport; Martha R Calamaras; C Lindsay DeVane; Jennifer L Donovan; Aquila J Beach; Stephanie Winn; Bettina T Knight; Bryan B Gibson; Adele C Viguera; Michael J Owens; Charles Nemeroff; Zachary N Stowe
Atypical antipsychotic administration during late pregnancy: placental passage and obstetrical outcomes.
The American journal of psychiatry 2007;164(8):1214-20.
2007: Karen A Cooper; Esther Campos-Giménez; Diego Jiménez Alvarez; Kornél Nagy; Jennifer L Donovan; Gary Williamson
Rapid reversed phase ultra-performance liquid chromatography analysis of the major cocoa polyphenols and inter-relationships of their concentrations in chocolate.
Journal of agricultural and food chemistry 2007;55(8):2841-7.
2007: Hao-Jie Zhu; Jun-Sheng Wang; Hao-Jie Zhu; Jennifer L Donovan; Bryan B Gibson; C Lindsay DeVane
Risperidone and paliperidone inhibit p-glycoprotein activity in vitro.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(4):757-64.
2007: Hao-Jie Zhu; Jun-Sheng Wang; Jennifer L Donovan; C Lindsay DeVane; Bryan B Gibson; Hao-Jie Zhu
Sensitive quantification of atomoxetine in human plasma by HPLC with fluorescence detection using 4-(4,5-diphenyl-1H-imidazole-2-yl) benzoyl chloride derivatization.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;846(1-2):351-4.
2007: Jun-Sheng Wang; D Jeffrey Newport; Zachary N Stowe; Jennifer L Donovan; Page B Pennell; C Lindsay DeVane
The emerging importance of transporter proteins in the psychopharmacological treatment of the pregnant patient.
Drug metabolism reviews 2007;39(4):723-46.
2006: Jennifer L Donovan; Vanessa Crespy; Manuel Oliveira; Karen A Cooper; Bryan B Gibson; Gary Williamson
(+)-Catechin is more bioavailable than (-)-catechin: relevance to the bioavailability of catechin from cocoa.
Free radical research 2006;40(10):1029-34.
2006: Jun-Sheng Wang; Hao-Jie Zhu; Hao-Jie Zhu; Jennifer L Donovan; C Lindsay DeVane
Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein.
Psychopharmacology 2006;187(4):415-23.
2006: C Lindsay DeVane; Zachary N Stowe; Jennifer L Donovan; D Jeffrey Newport; Page B Pennell; James C Ritchie; Michael J Owens; Jun-Sheng Wang
Therapeutic drug monitoring of psychoactive drugs during pregnancy in the genomic era: challenges and opportunities.
Journal of psychopharmacology (Oxford, England) 2006;20(4 Suppl):54-9.
2006: Hao-Jie Zhu; Jun-Sheng Wang; C Lindsay DeVane; Robin L Williard; Jennifer L Donovan; Lawrence D Middaugh; Bryan B Gibson; Kennerly S Patrick; Hao-Jie Zhu
The role of the polymorphic efflux transporter P-glycoprotein on the brain accumulation of d-methylphenidate and d-amphetamine.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(7):1116-21.
2006: Hao-Jie Zhu; Jun-Sheng Wang; Hao-Jie Zhu; Jennifer L Donovan; Bryan B Gibson; Holly A Gefroh; C Lindsay DeVane
Characterization of P-glycoprotein inhibition by major cannabinoids from marijuana.
The Journal of pharmacology and experimental therapeutics 2006;317(2):850-7.
2006: Hao-Jie Zhu; C Lindsay DeVane; Robert Malcolm; Holly A Gefroh; Jun-Sheng Wang; Hao-Jie Zhu; Jennifer L Donovan
Pharmacokinetics of olanzapine after single-dose oral administration of standard tablet versus normal and sublingual administration of an orally disintegrating tablet in normal volunteers.
Journal of clinical pharmacology 2006;46(2):164-71.
2006: Robert Malcolm; Karla Swayngim; Jennifer L Donovan; C Lindsay DeVane; Ahmed Elkashef; Nora Chiang; Roberta Khan; Jurij Mojsiak; Donald L. Myrick; Sarra Hedden; Kristi Cochran; Robert F Woolson
Modafinil and cocaine interactions.
The American journal of drug and alcohol abuse 2006;32(4):577-87.
2006: Jun-Sheng Wang; C Lindsay DeVane; Bryan B Gibson; Jennifer L Donovan; Hao-Jie Zhu; Hao-Jie Zhu
Population pharmacokinetic analysis of drug-drug interactions among risperidone, bupropion, and sertraline in CF1 mice.
Psychopharmacology 2006;183(4):490-9.
2005: Jennifer L Donovan; C Lindsay DeVane; John G Lewis; Jun-Sheng Wang; Ying Ruan; Kenneth D Chavin; John S Markowitz
Effects of St John's wort (Hypericum perforatum L.) extract on plasma androgen concentrations in healthy men and women: a pilot study.
Phytotherapy research : PTR 2005;19(10):901-6.
2005: Jennifer L Donovan; C Lindsay DeVane; Kenneth D Chavin; Jim Oates; Chinedu J Njoku; Kennerly S Patrick; Ryan N Fiorini; John S Markowitz
Oral administration of a decaffeinated green tea (Camellia sinensis) extract did not alter urinary 8-epi-prostaglandin F(2 alpha), a biomarker for in-vivo lipid peroxidation.
The Journal of pharmacy and pharmacology 2005;57(10):1365-9.
2005: John S Markowitz; C Lindsay DeVane; John G Lewis; Kenneth D Chavin; Jun-Sheng Wang; Jennifer L Donovan
Effect of Ginkgo biloba extract on plasma steroid concentrations in healthy volunteers: a pilot study.
Pharmacotherapy 2005;25(10):1337-40.
2005: Jun-Sheng Wang; John S Markowitz; Jennifer L Donovan; C Lindsay DeVane
P-glycoprotein does not actively transport nicotine and cotinine.
Addiction biology 2005;10(2):127-9.
2005: Ryan N Fiorini; Jennifer L Donovan; David Rodwell; Zachary Evans; Gang Cheng; Harold D May; Charles E Milliken; John S Markowitz; Crystal Campbell; Julia K Haines; Michael G Schmidt; Kenneth D Chavin
Short-term administration of (-)-epigallocatechin gallate reduces hepatic steatosis and protects against warm hepatic ischemia/reperfusion injury in steatotic mice.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2005;11(3):298-308.
2005: Jennifer L Donovan; C Lindsay DeVane; Robert Malcolm; Jurij Mojsiak; C Nora Chiang; Ahmed Elkashef; Robin M Taylor
Modafinil influences the pharmacokinetics of intravenous cocaine in healthy cocaine-dependent volunteers.
Clinical pharmacokinetics 2005;44(7):753-65.
2004: Jun-Sheng Wang; Ying Ruan; Robin M Taylor; Jennifer L Donovan; John S Markowitz; C Lindsay DeVane
The brain entry of risperidone and 9-hydroxyrisperidone is greatly limited by P-glycoprotein.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2004;7(4):415-9.
2004: Jennifer L Donovan; C Lindsay DeVane; Kenneth D Chavin; Jun-Sheng Wang; Bryan B Gibson; Holly A Gefroh; John S Markowitz
Multiple night-time doses of valerian (Valeriana officinalis) had minimal effects on CYP3A4 activity and no effect on CYP2D6 activity in healthy volunteers.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(12):1333-6.
2004: Jennifer L Donovan; Kenneth D Chavin; C Lindsay DeVane; Robin M Taylor; Jun-Sheng Wang; Ying Ruan; John S Markowitz
Green tea (Camellia sinensis) extract does not alter cytochrome p450 3A4 or 2D6 activity in healthy volunteers.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(9):906-8.
2004: Claudine Manach; Jennifer L Donovan
Pharmacokinetics and metabolism of dietary flavonoids in humans.
Free radical research 2004;38(8):771-85.
2004: Paul A Kroon; Michael N Clifford; Alan Crozier; Andrea J Day; Jennifer L Donovan; Claudine Manach; Gary Williamson
How should we assess the effects of exposure to dietary polyphenols in vitro?
The American journal of clinical nutrition 2004;80(1):15-21.
2004: John S Markowitz; Jennifer L Donovan; C Lindsay DeVane; Kenneth D Chavin
Common herbal supplements did not produce false-positive results on urine drug screens analyzed by enzyme immunoassay.
Journal of analytical toxicology 2004;28(4):272-3.
2004: Jun-Sheng Wang; Ying Ruan; Robin M Taylor; Jennifer L Donovan; John S Markowitz; C Lindsay DeVane
Brain penetration of methadone (R)- and (S)-enantiomers is greatly increased by P-glycoprotein deficiency in the blood-brain barrier of Abcb1a gene knockout mice.
Psychopharmacology 2004;173(1-2):132-8.
2004: Jennifer L Donovan
Flavonoids and the risk of cardiovascular disease in women.
The American journal of clinical nutrition 2004;79(3):522-3; author reply 523.
2004: Jun-Sheng Wang; Robin Taylor; Ying Ruan; Jennifer L Donovan; John S Markowitz; C Lindsay De Vane
Olanzapine penetration into brain is greater in transgenic Abcb1a P-glycoprotein-deficient mice than FVB1 (wild-type) animals.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(3):551-7.
2004: C Lindsay DeVane; Jennifer L Donovan; Heidi L Liston; John S Markowitz; Kenneth T Cheng; S Craig Risch; Lauren Willard
Comparative CYP3A4 inhibitory effects of venlafaxine, fluoxetine, sertraline, and nefazodone in healthy volunteers.
Journal of clinical psychopharmacology 2004;24(1):4-10.
2003: Hao-Jie Zhu; Jennifer L Donovan; C Lindsay DeVane; Robin M Taylor; Ying Ruan; Jun-Sheng Wang; Kenneth D Chavin
Multiple doses of saw palmetto (Serenoa repens) did not alter cytochrome P450 2D6 and 3A4 activity in normal volunteers.
Clinical pharmacology and therapeutics 2003;74(6):536-42.
2003: John S Markowitz; Jennifer L Donovan; C Lindsay DeVane; Laura Sipkes; Kenneth D Chavin
Multiple-dose administration of Ginkgo biloba did not affect cytochrome P-450 2D6 or 3A4 activity in normal volunteers.
Journal of clinical psychopharmacology 2003;23(6):576-81.
2003: Marie-Paule Gonthier; Jennifer L Donovan; Odile Texier; Catherine Felgines; Christian Remesy; Augustin Scalbert
Metabolism of dietary procyanidins in rats.
Free radical biology & medicine 2003;35(8):837-44.
2003: John S Markowitz; Jennifer L Donovan; C Lindsay DeVane; Robin M Taylor; Ying Ruan; Jun-Sheng Wang; Kenneth D Chavin
Effect of St John's wort on drug metabolism by induction of cytochrome P450 3A4 enzyme.
JAMA : the journal of the American Medical Association 2003;290(11):1500-4.
2003: John S Markowitz; C Lindsay DeVane; Kenneth D Chavin; Robin M Taylor; Ying Ruan; Jennifer L Donovan
Effects of garlic (Allium sativum L.) supplementation on cytochrome P450 2D6 and 3A4 activity in healthy volunteers.
Clinical pharmacology and therapeutics 2003;74(2):170-7.
2003: Jennifer L Donovan; C Lindsay DeVane; David W Boulton; Seetal Dodd; John S Markowitz
Dietary levels of quinine in tonic water do not inhibit CYP2D6 in vivo.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2003;41(8):1199-201.
2003: Jennifer L Donovan; C Lindsay DeVane; Kenneth D Chavin; Robin M Taylor; John S Markowitz
Siberian ginseng (Eleutheroccus senticosus) effects on CYP2D6 and CYP3A4 activity in normal volunteers.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(5):519-22.
2003: Jennifer L Donovan; Robert Malcolm; John S Markowitz; C Lindsay DeVane
Chiral analysis of d- and l-modafinil in human serum: application to human pharmacokinetic studies.
Therapeutic drug monitoring 2003;25(2):197-202.
2003: Marie-Paule Gonthier; Véronique Cheynier; Jennifer L Donovan; Claudine Manach; Christine Morand; Isabelle Mila; catherine Lapierre; Christian Rémésy; Augustin Scalbert
Microbial aromatic acid metabolites formed in the gut account for a major fraction of the polyphenols excreted in urine of rats fed red wine polyphenols.
The Journal of nutrition 2003;133(2):461-7.
2002: Jennifer L Donovan; Claudine Manach; Laurent Y Rios; Christine Morand; Augustin Scalbert; Christian Rémésy
Procyanidins are not bioavailable in rats fed a single meal containing a grapeseed extract or the procyanidin dimer B3.
The British journal of nutrition 2002;87(4):299-306.
2002: Jennifer L Donovan; Siddika Karakas; Bruce german; Andrew L Waterhouse
Urinary excretion of catechin metabolites by human subjects after red wine consumption.
The British journal of nutrition 2002;87(1):31-7.
2001: Jennifer L Donovan; Vanessa Crespy; Claudine Manach; Christine Morand; Catherine Besson; Augustin Scalbert; Christian Rémésy
Catechin is metabolized by both the small intestine and liver of rats.
The Journal of nutrition 2001;131(6):1753-7.
2001: Jennifer L Donovan; C Lindsay DeVane
A primer on caffeine pharmacology and its drug interactions in clinical psychopharmacology.
Psychopharmacology bulletin 2001;35(3):30-48.
2001: Christine Morand; Claudine Manach; Jennifer L Donovan; Christian Remesy
Preparation and characterization of flavonoid metabolites present in biological samples.
Methods in enzymology 2001;335():115-21.
2000: J R Bell; Jennifer L Donovan; Rodney Wong; Andrew L Waterhouse; Bruce german; Rosemary Walzem; Siddika Karakas
(+)-Catechin in human plasma after ingestion of a single serving of reconstituted red wine.
The American journal of clinical nutrition 2000;71(1):103-8.
1999: Jennifer L Donovan; J R Bell; Siddika Karakas; Bruce german; Rosemary Walzem; Robert J Hansen; Andrew L Waterhouse
Catechin is present as metabolites in human plasma after consumption of red wine.
The Journal of nutrition 1999;129(9):1662-8.
1999: Jennifer L Donovan; D L Luthria; P Stremple; Andrew L Waterhouse
Analysis of (+)-catechin, (-)-epicatechin and their 3'- and 4'-O-methylated analogs. A comparison of sensitive methods.
Journal of chromatography. B, Biomedical sciences and applications 1999;726(1-2):277-83.
1996: Andrew L Waterhouse; J R Shirley; Jennifer L Donovan
Antioxidants in chocolate.
Lancet 1996;348(9030):834.