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Iván D'Orso

Research Profile

Chemicals & Drugs

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Genes & Molecular Sequences

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Protein Binding

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HIV-1

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TOP 3
Iván D'Orso; Tyler B Faust; Gwendolyn M Jang; Alexander W Pastuszak; Elizabeth Quezada; David S Booth; Alan D Frankel
Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA.
Tyler Faust; Alan Frankel; Iván D'Orso
Transcription control by long non-coding RNAs.
Stefanie Jäger; Natali Gulbahce; Peter Cimermancic; Joshua Kane; Nanhai He; Seemay Chou; Iván D'Orso; Jason Fernandes; Gwendolyn Jang; Alan D Frankel; Tom Alber; Qiang Zhou ; Nevan J Krogan
Purification and characterization of HIV-human protein complexes.

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All Publications

2012: Iván D'Orso; Tyler B Faust; Gwendolyn M Jang; Alexander W Pastuszak; Elizabeth Quezada; David S Booth; Alan D Frankel
Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA.
Molecular and cellular biology 2012;32(23):4780-93.
2012: Tyler Faust; Alan Frankel; Iván D'Orso
Transcription control by long non-coding RNAs.
Transcription 2012;3(2):78-86.
2011: Stefanie Jäger; Natali Gulbahce; Peter Cimermancic; Joshua Kane; Nanhai He; Seemay Chou; Iván D'Orso; Jason Fernandes; Gwendolyn Jang; Alan D Frankel; Tom Alber; Qiang Zhou ; Nevan J Krogan
Purification and characterization of HIV-human protein complexes.
Methods (San Diego, Calif.) 2011;53(1):13-9.
2010: Iván D'Orso; Alan D Frankel
RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation.
Nature structural & molecular biology 2010;17(7):815-21.
2009: Iván D'Orso; Alan D Frankel
Tat acetylation modulates assembly of a viral-host RNA-protein transcription complex.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3101-6.
2008: Iván D'Orso; Jocelyn R Grunwell; Robert L Nakamura; Chandreyee Das; Alan D Frankel
Targeting tat inhibitors in the assembly of human immunodeficiency virus type 1 transcription complexes.
Journal of virology 2008;82(19):9492-504.
2008: Matthew D Daugherty; Iván D'Orso; Alan D Frankel
A solution to limited genomic capacity: using adaptable binding surfaces to assemble the functional HIV Rev oligomer on RNA.
Molecular cell 2008;31(6):824-34.
2007: Claudia Hartmann; Corinna Benz; Stefanie Brems; Louise Ellis; Van-Duc Luu; Mhairi Stewart; Iván D'Orso; Christian Busold; Kurt Fellenberg; Alberto C C Frasch; Mark Carrington; Jörg D Hoheisel; Christine E Clayton
Small trypanosome RNA-binding proteins TbUBP1 and TbUBP2 influence expression of F-box protein mRNAs in bloodstream trypanosomes.
Eukaryotic cell 2007;6(11):1964-78.
2007: Adriana V Jäger; Javier G De Gaudenzi; Alejandro Cassola; Iván D'Orso; Alberto C C Frasch
mRNA maturation by two-step trans-splicing/polyadenylation processing in trypanosomes.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(7):2035-42.
2005: Laurent Volpon; Iván D'Orso; Christopher R Young; Alberto C C Frasch; Kalle Gehring
NMR structural study of TcUBP1, a single RRM domain protein from Trypanosoma cruzi: contribution of a beta hairpin to RNA binding.
Biochemistry 2005;44(10):3708-17.
2005: Ileana C Cuevas; Alberto C C Frasch; Iván D'Orso
Insights into a CRM1-mediated RNA-nuclear export pathway in Trypanosoma cruzi.
Molecular and biochemical parasitology 2005;139(1):15-24.
2003: Nadeem Siddiqui; Guennadi Kozlov; Iván D'Orso; Jean-Francois Trempe; Kalle Gehring
Solution structure of the C-terminal domain from poly(A)-binding protein in Trypanosoma cruzi: a vegetal PABC domain.
Protein science : a publication of the Protein Society 2003;12(9):1925-33.
2003: Javier G De Gaudenzi; Iván D'Orso; Alberto C C Frasch
RNA recognition motif-type RNA-binding proteins in Trypanosoma cruzi form a family involved in the interaction with specific transcripts in vivo.
The Journal of biological chemistry 2003;278(21):18884-94.
2003: Iván D'Orso; Javier G De Gaudenzi; Alberto C C Frasch
RNA-binding proteins and mRNA turnover in trypanosomes.
Trends in parasitology 2003;19(4):151-5.
2002: Iván D'Orso; Alberto C C Frasch
TcUBP-1, an mRNA destabilizing factor from trypanosomes, homodimerizes and interacts with novel AU-rich element- and Poly(A)-binding proteins forming a ribonucleoprotein complex.
The Journal of biological chemistry 2002;277(52):50520-8.
2001: Iván D'Orso; Alberto C C Frasch
TcUBP-1, a developmentally regulated U-rich RNA-binding protein involved in selective mRNA destabilization in trypanosomes.
The Journal of biological chemistry 2001;276(37):34801-9.
2001: Iván D'Orso; Alberto C C Frasch
Functionally different AU- and G-rich cis-elements confer developmentally regulated mRNA stability in Trypanosoma cruzi by interaction with specific RNA-binding proteins.
The Journal of biological chemistry 2001;276(19):15783-93.
2000: Javier Di noia; Iván D'Orso; Daniel O Sánchez; Alberto C C Frasch
AU-rich elements in the 3'-untranslated region of a new mucin-type gene family of Trypanosoma cruzi confers mRNA instability and modulates translation efficiency.
The Journal of biological chemistry 2000;275(14):10218-27.
1998: Javier Di noia; Iván D'Orso; Lena Aslund; Daniel O Sánchez; Alberto C C Frasch
The Trypanosoma cruzi mucin family is transcribed from hundreds of genes having hypervariable regions.
The Journal of biological chemistry 1998;273(18):10843-50.