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Sophie Doublier

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Enrico Lupia; Sophie Doublier; Sharon J Elliot; Fabrizio Grosjean; Ivan Tack; Helen Vlassara; Feng Zheng; Gary E Striker
Pentosan polysulfate inhibits atherosclerosis in Watanabe heritable hyperlipidemic rabbits: differential modulation of metalloproteinase-2 and -9.
Sophie Doublier; Dario Ghigo; Manuela Polimeni; Chiara Riganti; Elena Allia; Laura Annaratone; Dimas C Belisario; Amalia Bosia; Anna Sapino
HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast.
Elisabetta Aldieri; Pier Giacomo Betta; Amalia Bosia; Sophie Doublier; Elena Gazzano; Sara Orecchia; Manuela Polimeni; Chiara Riganti; Francesca Silvagno; Dario Ghigo
Antioxidants prevent the RhoA inhibition evoked by crocidolite asbestos in human mesothelial and mesothelioma cells.

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All Publications

2012: Enrico Lupia; Sophie Doublier; Sharon J Elliot; Fabrizio Grosjean; Ivan Tack; Helen Vlassara; Feng Zheng; Gary E Striker
Pentosan polysulfate inhibits atherosclerosis in Watanabe heritable hyperlipidemic rabbits: differential modulation of metalloproteinase-2 and -9.
Laboratory investigation; a journal of technical methods and pathology 2012;92(2):236-45.
2012: Sophie Doublier; Dario Ghigo; Manuela Polimeni; Chiara Riganti; Elena Allia; Laura Annaratone; Dimas C Belisario; Amalia Bosia; Anna Sapino
HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast.
BMC cancer 2012;12():4.
2011: Elisabetta Aldieri; Pier Giacomo Betta; Amalia Bosia; Sophie Doublier; Elena Gazzano; Sara Orecchia; Manuela Polimeni; Chiara Riganti; Francesca Silvagno; Dario Ghigo
Antioxidants prevent the RhoA inhibition evoked by crocidolite asbestos in human mesothelial and mesothelioma cells.
American journal of respiratory cell and molecular biology 2011;45(3):625-31.
2011: Joanna Kopecka; Lina Matera; Amalia Bosia; Davide Brusa; Ivana Campia; Sophie Doublier; Dario Ghigo; Chiara Riganti
Nitric oxide and P-glycoprotein modulate the phagocytosis of colon cancer cells.
Journal of cellular and molecular medicine 2011;15(7):1492-504.
2011: Sophie Doublier; Enrico Lupia; Paola Catanuto; Simone Periera-Simon; Xiaomei Xia; Ken Korach; Mariana Berho; Sharon J Elliot; Michael Karl
Testosterone and 17β-estradiol have opposite effects on podocyte apoptosis that precedes glomerulosclerosis in female estrogen receptor knockout mice.
Kidney international 2011;79(4):404-13.
2011: Chiara Riganti; I Campia; J Kopecka; Elena Gazzano; Sophie Doublier; Elisabetta Aldieri; Amalia Bosia; Dario Ghigo
Pleiotropic effects of cardioactive glycosides.
Current medicinal chemistry 2011;18(6):872-85.
2011: Sophie Doublier; Enrico Lupia; Paola Catanuto; Sharon J Elliot
Estrogens and progression of diabetic kidney damage.
Current diabetes reviews 2011;7(1):28-34.
2010: Elena Gazzano; L Bergandi; Chiara Riganti; Elisabetta Aldieri; Sophie Doublier; Costanzo Costamagna; Amalia Bosia; Dario Ghigo
Fluoride effects: the two faces of janus.
Current medicinal chemistry 2010;17(22):2431-41.
2009: Paola Catanuto; Sophie Doublier; Enrico Lupia; Alessia Fornoni; Mariana Berho; Michael Karl; Gary E Striker; Xiaomei Xia; Sharon J Elliot
17 beta-estradiol and tamoxifen upregulate estrogen receptor beta expression and control podocyte signaling pathways in a model of type 2 diabetes.
Kidney international 2009;75(11):1194-201.
2009: Chiara Riganti; Sophie Doublier; D Viarisio; Erica Miraglia; GIAN PIERO PESCARMONA; Dario Ghigo; Amalia Bosia
Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1alpha and P-glycoprotein overexpression.
British journal of pharmacology 2009;156(7):1054-66.
2008: Sophie Doublier; Chiara Riganti; Claudia Voena; Costanzo Costamagna; Elisabetta Aldieri; GIAN PIERO PESCARMONA; Dario Ghigo; Amalia Bosia
RhoA silencing reverts the resistance to doxorubicin in human colon cancer cells.
Molecular cancer research : MCR 2008;6(10):1607-20.
2008: Chiara Riganti; Sophie Doublier; Costanzo Costamagna; Elisabetta Aldieri; GIAN PIERO PESCARMONA; Dario Ghigo; Amalia Bosia
Activation of nuclear factor-kappa B pathway by simvastatin and RhoA silencing increases doxorubicin cytotoxicity in human colon cancer HT29 cells.
Molecular pharmacology 2008;74(2):476-84.
2008: Chiara Riganti; Sophie Doublier; Elisabetta Aldieri; Sara Orecchia; Pier Giacomo Betta; Elena Gazzano; Dario Ghigo; Amalia Bosia
Asbestos induces doxorubicin resistance in MM98 mesothelioma cells via HIF-1alpha.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;32(2):443-51.
2008: Chiara Riganti; Elisabetta Aldieri; Sophie Doublier; Amalia Bosia; Dario Ghigo
Statins-mediated inhibition of rho GTPases as a potential tool in anti-tumor therapy.
Mini reviews in medicinal chemistry 2008;8(6):609-18.
2008: Chiara Riganti; Costanzo Costamagna; Sophie Doublier; Erica Miraglia; Manuela Polimeni; Amalia Bosia; Dario Ghigo
The NADPH oxidase inhibitor apocynin induces nitric oxide synthesis via oxidative stress.
Toxicology and applied pharmacology 2008;228(3):277-85.
2007: Sophie Doublier; Monica Ceretto; Enrico Lupia; Stefania Bravo; Benedetta Bussolati; Giovanni Camussi
The proangiogenic phenotype of tumor-derived endothelial cells is reverted by the overexpression of platelet-activating factor acetylhydrolase.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(19):5710-8.
2007: Sharon J Elliot; Mariana Berho; K Korach; Sophie Doublier; Enrico Lupia; Gary E Striker; Michael Karl
Gender-specific effects of endogenous testosterone: female alpha-estrogen receptor-deficient C57Bl/6J mice develop glomerulosclerosis.
Kidney international 2007;72(4):464-72.
2007: Sophie Doublier; Cristina Zennaro; Tiziana Spatola; Enrico Lupia; Antonella Bottelli; Maria Chiara Deregibus; Michele Carraro; Pier Giulio Conaldi; Giovanni Camussi
HIV-1 Tat reduces nephrin in human podocytes: a potential mechanism for enhanced glomerular permeability in HIV-associated nephropathy.
AIDS (London, England) 2007;21(4):423-32.
2006: Julie Peltier; Agnès Bellocq; Joëlle Perez; Sophie Doublier; Yi-Chun Xu Dubois; Jean-Philippe Haymann; Giovanni Camussi; Laurent Baud
Calpain activation and secretion promote glomerular injury in experimental glomerulonephritis: evidence from calpastatin-transgenic mice.
Journal of the American Society of Nephrology : JASN 2006;17(12):3415-23.
2005: Maria M Zanone; Enrica Favaro; Sophie Doublier; Biliana Lozanoska-Ochser; Maria Chiara Deregibus; James E Greening; Guo Huang; N Klein; Paolo Cavallo-Perin; Mark Peakman; Giovanni Camussi
Expression of nephrin by human pancreatic islet endothelial cells.
Diabetologia 2005;48(9):1789-97.
2005: Sophie Doublier; Luca Musante; Enrico Lupia; Giovanni Candiano; Tiziana Spatola; Gianluca Caridi; Cristina Zennaro; Michele Carraro; Gian Marco Ghiggeri; Giovanni Camussi
Direct effect of plasma permeability factors from patients with idiopatic FSGS on nephrin and podocin expression in human podocytes.
International journal of molecular medicine 2005;16(1):49-58.
2005: Benedetta Bussolati; Maria Chiara Deregibus; Valentina Fonsato; Sophie Doublier; Tiziana Spatola; Simone Procida; Francesco Di Carlo; Giovanni Camussi
Statins prevent oxidized LDL-induced injury of glomerular podocytes by activating the phosphatidylinositol 3-kinase/AKT-signaling pathway.
Journal of the American Society of Nephrology : JASN 2005;16(7):1936-47.
2003: Joëlle Perez; Cécile Viollet; Sophie Doublier; Catherine Videau; Jacques Epelbaum; Laurent Baud
Somatostatin binds to murine macrophages through two distinct subsets of receptors.
Journal of neuroimmunology 2003;138(1-2):38-44.
2003: Sophie Doublier; Gennaro Salvidio; Enrico Lupia; Vesa Ruotsalainen; Daniela Verzola; Giacomo Deferrari; Giovanni Camussi
Nephrin expression is reduced in human diabetic nephropathy: evidence for a distinct role for glycated albumin and angiotensin II.
Diabetes 2003;52(4):1023-30.
2002: Maria Chiara Deregibus; Vincenzo Cantaluppi; Sophie Doublier; Maria Felice Brizzi; Ilaria Deambrosis; Adriana Albini; Giovanni Camussi
HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells.
The Journal of biological chemistry 2002;277(28):25195-202.
2001: Vincenzo Cantaluppi; Livia Biancone; Mariarosaria Boccellino; Sophie Doublier; Roberto Benelli; Sebastiano Carlone; Adriana Albini; Giovanni Camussi
HIV type 1 Tat protein is a survival factor for Kaposi's sarcoma and endothelial cells.
AIDS research and human retroviruses 2001;17(10):965-76.
2001: Sophie Doublier; Vesa Ruotsalainen; Gennaro Salvidio; Enrico Lupia; Livia Biancone; Pier Giulio Conaldi; Paula Reponen; Karl Tryggvason; Giovanni Camussi
Nephrin redistribution on podocytes is a potential mechanism for proteinuria in patients with primary acquired nephrotic syndrome.
The American journal of pathology 2001;158(5):1723-31.
2001: Sophie Doublier; K Amri; Danielle Seurin; E Moreau; C Merlet-Benichou; Gary E Striker; Thierry Gilbert
Overexpression of human insulin-like growth factor binding protein-1 in the mouse leads to nephron deficit.
Pediatric research 2001;49(5):660-6.
2001: Laurent Baud; Bruno Fouqueray; Agnès Bellocq; Sophie Doublier; J Peltier
Repair of glomerular inflammation.
Advances in nephrology from the Necker Hospital 2001;31():243-56.
2000: Sophie Doublier; Charles Duyckaerts; Danielle Seurin; Michel Binoux
Impaired brain development and hydrocephalus in a line of transgenic mice with liver-specific expression of human insulin-like growth factor binding protein-1.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2000;10(5):267-74.
2000: Sophie Doublier; Danielle Seurin; Bruno Fouqueray; M C Verpont; patrice callard; Liliane J Striker; Gary E Striker; Michel Binoux; Laurent Baud
Glomerulosclerosis in mice transgenic for human insulin-like growth factor-binding protein-1.
Kidney international 2000;57(6):2299-307.
2000: LL Bellush; Sophie Doublier; A N Holland; Liliane J Striker; Gary E Striker; John J Kopchick
Protection against diabetes-induced nephropathy in growth hormone receptor/binding protein gene-disrupted mice.
Endocrinology 2000;141(1):163-8.
1999: Agnès Bellocq; Sophie Doublier; S Suberville; Joëlle Perez; Brigitte Escoubet; Bruno Fouqueray; D R Puyol; Laurent Baud
Somatostatin increases glucocorticoid binding and signaling in macrophages by blocking the calpain-specific cleavage of Hsp 90.
The Journal of biological chemistry 1999;274(52):36891-6.
1999: Agnès Bellocq; Sophie Doublier; Julie Peltier; S Suberville; Bruno Fouqueray; Laurent Baud
[Interactions between glucocorticoids and anti-inflammatory peptides].
Journal de la Société de biologie 1999;193(4-5):381-3.
1999: Laurent Baud; Bruno Fouqueray; Agnès Bellocq; Sophie Doublier; A Dumoulin
Growth hormone and somatostatin in glomerular injury.
Journal of nephrology 1999;12(1):18-23.
1998: Oliver Lenz; F Zheng; J Vilar; Sophie Doublier; Enrico Lupia; SB Schwedler; Liliane J Striker; Gary E Striker
The inheritance of glomerulosclerosis in mice is controlled by multiple quantitative trait loci.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1998;13(12):3074-8.
1998: Laurent Baud; Bruno Fouqueray; S Suberville; Sophie Doublier
Interleukin 10: a logical candidate for suppressing glomerular inflammation?
Experimental nephrology 1998;6(1):22-7.
1997: E Gay; Danielle Seurin; Sylvie Babajko; Sophie Doublier; Michèle Cazillis; Michel Binoux
Liver-specific expression of human insulin-like growth factor binding protein-1 in transgenic mice: repercussions on reproduction, ante- and perinatal mortality and postnatal growth.
Endocrinology 1997;138(7):2937-47.