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Stephen Downs
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Network (preview)
6
Humpherson, Peter
6
Leese, Henry
5
Chen, Jing
3
Colton, Shannondoah
3
LaRosa, Cean
2
Hardie, Grahame
2
Moley, Kelle
1
Pieper, Galen
1
Ruan, Benfang
1
Schroepfer, George
1
Chang, Aimee
1
Cottom, Joshua
1
Dienhart, Mary
1
Eppig, John
1
Chi, Maggie M-Y
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All Publications
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2009: Chen Jing; Chi Maggie M; Moley Kelle H; Downs Stephen M
cAMP pulsing of denuded mouse oocytes increases meiotic resumption via activation of AMP-activated protein kinase.
Reproduction (Cambridge, England) 2009;138(5):759-70.
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2009: Downs Stephen M; Mosey Jessica L; Klinger Jonathan
Fatty acid oxidation and meiotic resumption in mouse oocytes.
Molecular reproduction and development 2009;76(9):844-53.
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2008: Chen Jing; Downs Stephen M
AMP-activated protein kinase is involved in hormone-induced mouse oocyte meiotic maturation in vitro.
Developmental biology 2008;313(1):47-57.
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2008: Downs Stephen M; Chen Jing
EGF-like peptides mediate FSH-induced maturation of cumulus cell-enclosed mouse oocytes.
Molecular reproduction and development 2008;75(1):105-14.
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2007: LaRosa Cean; Downs Stephen M
Meiotic induction by heat stress in mouse oocytes: involvement of AMP-activated protein kinase and MAPK family members.
Biology of reproduction 2007;76(3):476-86.
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2006: Downs Stephen M; Chen Jing
Induction of meiotic maturation in mouse oocytes by adenosine analogs.
Molecular reproduction and development 2006;73(9):1159-68.
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2006: Chen Jing; Hudson Emma; Chi Maggie M; Chang Aimee S; Moley Kelle H; Hardie D Graham; Downs Stephen M
AMPK regulation of mouse oocyte meiotic resumption in vitro.
Developmental biology 2006;291(2):227-38.
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2006: Downs Stephen M; Gilles Ryan; Vanderhoef Christopher; Humpherson Peter G; Leese Henry J
Differential response of cumulus cell-enclosed and denuded mouse oocytes in a meiotic induction model system.
Molecular reproduction and development 2006;73(3):379-89.
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2006: LaRosa Cean; Downs Stephen M
Stress stimulates AMP-activated protein kinase and meiotic resumption in mouse oocytes.
Biology of reproduction 2006;74(3):585-92.
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2005: LaRosa Cean; Downs Stephen M
MEK inhibitors block AICAR-induced maturation in mouse oocytes by a MAPK-independent mechanism.
Molecular reproduction and development 2005;70(2):235-45.
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2004: Colton Shannondoah A; Downs Stephen M
Potential role for the sorbitol pathway in the meiotic dysfunction exhibited by oocytes from diabetic mice.
Journal of experimental zoology. Part A, Comparative experimental biology 2004;301(5):439-48.
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2003: Downs Stephen M; Verhoeven Amelia
Glutamine and the maintenance of meiotic arrest in mouse oocytes: influence of culture medium, glucose, and cumulus cells.
Molecular reproduction and development 2003;66(1):90-7.
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2003: Colton Shannondoah A; Humpherson Peter G; Leese Henry J; Downs Stephen M
Physiological changes in oocyte-cumulus cell complexes from diabetic mice that potentially influence meiotic regulation.
Biology of reproduction 2003;69(3):761-70.
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2002: Colton Shannondoah A; Pieper Galen M; Downs Stephen M
Altered meiotic regulation in oocytes from diabetic mice.
Biology of reproduction 2002;67(1):220-31.
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2002: Downs Stephen M; Hudson Emma R; Hardie D Grahame
A potential role for AMP-activated protein kinase in meiotic induction in mouse oocytes.
Developmental biology 2002;245(1):200-12.
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2002: Downs Stephen M; Humpherson Peter G; Leese Henry J
Pyruvate utilization by mouse oocytes is influenced by meiotic status and the cumulus oophorus.
Molecular reproduction and development 2002;62(1):113-23.
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2002: Downs S M
The biochemistry of oocyte maturation.
Ernst Schering Research Foundation workshop 2002;(41):81-99.
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2001: Downs S M
A gap-junction-mediated signal, rather than an external paracrine factor, predominates during meiotic induction in isolated mouse oocytes.
Zygote (Cambridge, England) 2001;9(1):71-82.
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2001: Downs S M; Cottom J; Hunzicker-Dunn M
Protein kinase C and meiotic regulation in isolated mouse oocytes.
Molecular reproduction and development 2001;58(1):101-15.
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2001: Downs S M; Ruan B; Schroepfer G J
Meiosis-activating sterol and the maturation of isolated mouse oocytes.
Biology of reproduction 2001;64(1):80-9.
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2000: Downs S M; Hudson E D
Energy substrates and the completion of spontaneous meiotic maturation.
Zygote (Cambridge, England) 2000;8(4):339-51.
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2000: Downs S M
Adenosine blocks hormone-induced meiotic maturation by suppressing purine de novo synthesis.
Molecular reproduction and development 2000;56(2):172-9.
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1999: Downs S M
Uptake and metabolism of adenosine mediate a meiosis-arresting action on mouse oocytes.
Molecular reproduction and development 1999;53(2):208-21.
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1999: Downs S M; Utecht A M
Metabolism of radiolabeled glucose by mouse oocytes and oocyte-cumulus cell complexes.
Biology of reproduction 1999;60(6):1446-52.
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1998: Downs S M
Precursors of the purine backbone augment the inhibitory action of hypoxanthine and dibutyryl cAMP on mouse oocyte maturation.
The Journal of experimental zoology 1998;282(3):376-84.
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1998: Downs S M; Humpherson P G; Leese H J
Meiotic induction in cumulus cell-enclosed mouse oocytes: involvement of the pentose phosphate pathway.
Biology of reproduction 1998;58(4):1084-94.
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1997: Downs S M
Hypoxanthine regulation of oocyte maturation in the mouse: insights using hypoxanthine phosphoribosyltransferase-deficient animals.
Biology of reproduction 1997;57(1):54-62.
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1997: Downs S M; Houghton F D; Humpherson P G; Leese H J
Substrate utilization and maturation of cumulus cell-enclosed mouse oocytes: evidence that pyruvate oxidation does not mediate meiotic induction.
Journal of reproduction and fertility 1997;110(1):1-10.
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1997: Downs S M; Mastropolo A M
Culture conditions affect meiotic regulation in cumulus cell-enclosed mouse oocytes.
Molecular reproduction and development 1997;46(4):551-66.
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1997: Downs S M
Involvement of purine nucleotide synthetic pathways in gonadotropin-induced meiotic maturation in mouse cumulus cell-enclosed oocytes.
Molecular reproduction and development 1997;46(2):155-67.
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1997: Dienhart M K; O'Brien M J; Downs S M
Uptake and salvage of hypoxanthine mediates developmental arrest in preimplantation mouse embryos.
Biology of reproduction 1997;56(1):1-13.
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1996: Dienhart M K; Downs S M
Cyclic AMP reversal of hypoxanthine-arrested preimplantation mouse embryos is EDTA-dependent.
Zygote (Cambridge, England) 1996;4(2):129-37.
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1996: Downs S M; Humpherson P G; Martin K L; Leese H J
Glucose utilization during gonadotropin-induced meiotic maturation in cumulus cell-enclosed mouse oocytes.
Molecular reproduction and development 1996;44(1):121-31.
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1995: Downs S M; Hunzicker-Dunn M
Differential regulation of oocyte maturation and cumulus expansion in the mouse oocyte-cumulus cell complex by site-selective analogs of cyclic adenosine monophosphate.
Developmental biology 1995;172(1):72-85.
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1995: Downs S M
The influence of glucose, cumulus cells, and metabolic coupling on ATP levels and meiotic control in the isolated mouse oocyte.
Developmental biology 1995;167(2):502-12.
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1994: Downs S M
Induction of meiotic maturation in vivo in the mouse by IMP dehydrogenase inhibitors: effects on the developmental capacity of ova.
Molecular reproduction and development 1994;38(3):293-302.
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1994: Downs S M
High performance liquid chromatography analysis of hypoxanthine metabolism in mouse oocyte-cumulus cell complexes: effects of purine metabolic perturbants.
Biology of reproduction 1994;50(6):1403-12.
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1994: Downs S M; Mastropolo A M
The participation of energy substrates in the control of meiotic maturation in murine oocytes.
Developmental biology 1994;162(1):154-68.
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1993: Downs S M
Purine control of mouse oocyte maturation: evidence that nonmetabolized hypoxanthine maintains meiotic arrest.
Molecular reproduction and development 1993;35(1):82-94.
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1992: Fagbohun C F; Downs S M
Requirement for glucose in ligand-stimulated meiotic maturation of cumulus cell-enclosed mouse oocytes.
Journal of reproduction and fertility 1992;96(2):681-97.
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1992: Downs S M; Buccione R; Eppig J J
Modulation of meiotic arrest in mouse oocytes by guanyl nucleotides and modifiers of G-proteins.
The Journal of experimental zoology 1992;262(4):391-404.
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1991: Fagbohun C F; Downs S M
Metabolic coupling and ligand-stimulated meiotic maturation in the mouse oocyte-cumulus cell complex.
Biology of reproduction 1991;45(6):851-9.
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1991: Downs S M; Dow M P
Hypoxanthine-maintained two-cell block in mouse embryos: dependence on glucose and effect of hypoxanthine phosphoribosyltransferase inhibitors.
Biology of reproduction 1991;44(6):1025-39.
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1991: Downs S M; Dow M P; Fagbohun C F
The meiotic response of cumulus cell-enclosed mouse oocytes to follicle-stimulating hormone in the presence of different macromolecules.
The Journal of experimental zoology 1991;258(3):373-83.
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1990: Downs S M
Protein synthesis inhibitors prevent both spontaneous and hormone-dependent maturation of isolated mouse oocytes.
Molecular reproduction and development 1990;27(3):235-43.
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1990: Fagbohun C F; Downs S M
Maturation of the mouse oocyte-cumulus cell complex: stimulation by lectins.
Biology of reproduction 1990;42(3):413-23.
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