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Sarah Doyle

Research Profile

Chemicals & Drugs

Anatomy

Disorders

Abdominal Obesity

Physiology

Co-author Network

Publications

TOP 3
Jennifer K Dowling; Sarah L Doyle; Nadia Benlarbi; Mary Canavan; Claire E McCoy; Luke A O'Neill; Christine E Loscher
Conjugated linoleic acid suppresses IRF3 activation via modulation of CD14.
Sarah L Doyle; Julia M Howard; Fiona E Lithander; Anne Marie Bennett; Claire L Donohoe; Ann Marie Mongan; Graham P Pidgeon; John V Reynolds; Joanne Lysaght
Establishing computed tomography-defined visceral fat area thresholds for use in obesity-related cancer research.
Sarah L Doyle; Gwyneth Jane Farrar; Joe G Hollyfield; Marian Humphries; Paul F Kenna; Anna-Sophia Kiang; E C Lavelle; Andres Mori; Luke A J O'Neill; Ema Ozaki; Robert G Salomon; Matthew Campbell; Peter Humphries
NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components.

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All Publications

2013: Jennifer K Dowling; Sarah L Doyle; Nadia Benlarbi; Mary Canavan; Claire E McCoy; Luke A O'Neill; Christine E Loscher
Conjugated linoleic acid suppresses IRF3 activation via modulation of CD14.
The Journal of nutritional biochemistry 2013;24(5):920-8.
2013: Sarah L Doyle; Julia M Howard; Fiona E Lithander; Anne Marie Bennett; Claire L Donohoe; Ann Marie Mongan; Graham P Pidgeon; John V Reynolds; Joanne Lysaght
Establishing computed tomography-defined visceral fat area thresholds for use in obesity-related cancer research.
Nutrition research (New York, N.Y.) 2013;33(3):171-9.
2012: Sarah L Doyle; Gwyneth Jane Farrar; Joe G Hollyfield; Marian Humphries; Paul F Kenna; Anna-Sophia Kiang; E C Lavelle; Andres Mori; Luke A J O'Neill; Ema Ozaki; Robert G Salomon; Matthew Campbell; Peter Humphries
NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components.
Nature medicine 2012;18(5):791-8.
2012: C L Donohoe; Sarah L Doyle; Joanne Lysaght; S McGarrigle; A O'Grady; Graham P Pidgeon; M C Cathcart; E Daly; John V Reynolds
Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma.
The British journal of surgery 2012;99(3):387-96.
2012: Sarah L Doyle; Stephen P Finn; Julia M Howard; Fiona E Lithander; Graham P Pidgeon; John V Reynolds; Claire L Donohoe; Joanne Lysaght
IGF-1 and its receptor in esophageal cancer: association with adenocarcinoma and visceral obesity.
The American journal of gastroenterology 2012;107(2):196-204.
2012: Sarah L Doyle; Joanne Lysaght; Claire L Donohoe; John V Reynolds
Visceral obesity, metabolic syndrome, insulin resistance and cancer.
The Proceedings of the Nutrition Society 2012;71(1):181-9.
2012: Sarah L Doyle; Terje Espevik; Harald Husebye; Dympna J Connolly; Luke A J O'Neill; Anne F McGettrick
The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation.
Nature communications 2012;3():707.
2011: John V Reynolds; C L Donohoe; Sarah L Doyle
Diet, obesity and cancer.
Irish journal of medical science 2011;180(2):521-7.
2011: Claire L Donohoe; Sarah L Doyle; John V Reynolds
Visceral adiposity, insulin resistance and cancer risk.
Diabetology & metabolic syndrome 2011;3():12.
2010: Sarah L Doyle; Joanne Lysaght; John V Reynolds
Obesity and post-operative complications in patients undergoing non-bariatric surgery.
Obesity reviews : an official journal of the International Association for the Study of Obesity 2010;11(12):875-86.
2010: Claire E McCoy; Frederick J Sheedy; Joseph E Qualls; Sarah L Doyle; Susan R Quinn; Peter J Murray; Luke A J O'Neill
IL-10 inhibits miR-155 induction by toll-like receptors.
The Journal of biological chemistry 2010;285(27):20492-8.
2009: Luke A J O'Neill; Clare E Bryant; Sarah L Doyle
Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.
Pharmacological reviews 2009;61(2):177-97.
2009: Eva M Palsson-McDermott; Sarah L Doyle; Anne F McGettrick; Matthew Hardy; Harald Husebye; Kathy Banahan; Mei Gong; Douglas T Golenbock; Terje Espevik; Luke A J O'Neill
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway.
Nature immunology 2009;10(6):579-86.
2007: Sarah L Doyle; Caroline Jefferies; Conleth Feighery; Luke A J O'Neill
Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase.
The Journal of biological chemistry 2007;282(51):36953-60.
2006: Sarah L Doyle; Luke A J O'Neill
Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity.
Biochemical pharmacology 2006;72(9):1102-13.
2006: Pearl Gray; Aisling Dunne; Constantinos Brikos; Caroline Jefferies; Sarah L Doyle; Luke A J O'Neill
MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction.
The Journal of biological chemistry 2006;281(15):10489-95.
2006: Ashley Mansell; Rosealee Smith; Sarah L Doyle; Pearl Gray; Jennifer E Fenner; Peter J Crack; Sandra E Nicholson; Douglas J Hilton; Luke A J O'Neill; Paul J Hertzog
Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation.
Nature immunology 2006;7(2):148-55.
2005: Sarah L Doyle; Caroline Jefferies; Luke A J O'Neill
Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFkappaB activation by lipopolysaccharide.
The Journal of biological chemistry 2005;280(25):23496-501.