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Yvonne Dragan

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Laura K Schnackenberg; Minjun Chen; Jinchun Sun; Ricky D Holland; Yvonne P Dragan; Weida Tong; WILLIAM J WELSH; Richard Beger
Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies.
Jinchun Sun; Laura K Schnackenberg; Ricky D Holland; Thomas C Schmitt; Glenn H Cantor; Yvonne P Dragan; Richard Beger
Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS.
Hong Fang; Xiaohui Fan; Lei Guo; Leming Shi; Roger Perkins; Weigong Ge; Yvonne P Dragan; Weida Tong
Self-self hybridization as an alternative experiment design to dye swap for two-color microarrays.

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2009: Laura K Schnackenberg; Minjun Chen; Jinchun Sun; Ricky D Holland; Yvonne P Dragan; Weida Tong; WILLIAM J WELSH; Richard Beger
Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies.
Toxicology and applied pharmacology 2009;235(1):25-32.
2008: Jinchun Sun; Laura K Schnackenberg; Ricky D Holland; Thomas C Schmitt; Glenn H Cantor; Yvonne P Dragan; Richard Beger
Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;871(2):328-40.
2007: Hong Fang; Xiaohui Fan; Lei Guo; Leming Shi; Roger Perkins; Weigong Ge; Yvonne P Dragan; Weida Tong
Self-self hybridization as an alternative experiment design to dye swap for two-color microarrays.
Omics : a journal of integrative biology 2007;11(1):14-24.
2006: Lei Guo; Edward K Lobenhofer; Charles Wang; Richard Shippy; Stephen C Harris; Lu Zhang; Nan Mei; Tao Chen; Damir Herman; Federico M Goodsaid; Patrick Hurban; Kenneth L Phillips; Jun Xu; Xutao Deng; Yongming Andrew Sun; Weida Tong; Yvonne P Dragan; Leming Shi
Rat toxicogenomic study reveals analytical consistency across microarray platforms.
Nature biotechnology 2006;24(9):1162-9.
2006: Lei Guo; Lu Zhang; Yongming Sun; Levan Muskhelishvili; Ernice Blann; Stacey Dial; Leming Shi; Gary Schroth; Yvonne P Dragan
Differences in hepatotoxicity and gene expression profiles by anti-diabetic PPAR gamma agonists on rat primary hepatocytes and human HepG2 cells.
Molecular diversity 2006;10(3):349-60.
2006: Igor P Pogribny; Sharon A Ross; Carolyn Wise; Marta Pogribna; Elisabeth A Jones; Volodymyr Tryndyak; S Jill James; Yvonne P Dragan; Lionel A Poirier
Irreversible global DNA hypomethylation as a key step in hepatocarcinogenesis induced by dietary methyl deficiency.
Mutation research 2006;593(1-2):80-7.
2006: Lei Guo; Hong Fang; Jim Collins; Xiao-hui Fan; Stacey Dial; Alex Wong; Kshama Mehta; Ernice Blann; Leming Shi; Weida Tong; Yvonne P Dragan
Differential gene expression in mouse primary hepatocytes exposed to the peroxisome proliferator-activated receptor alpha agonists.
BMC bioinformatics 2006;7 Suppl 2():S18.
2006: Jon G Wilkes; Dan A Buzatu; Diane J Dare; Yvonne P Dragan; M. Paul Chiarelli; Ricky D Holland; Michael Beaudoin; Thomas Heinze; Rajesh Nayak; Alexandre A Shvartsburg
Improved cell typing by charge-state deconvolution of matrix-assisted laser desorption/ionization mass spectra.
Rapid communications in mass spectrometry : RCM 2006;20(10):1595-603.
2006: Laura K Schnackenberg; Richard C Jones; Sheeno Thyparambil; Jason T Taylor; Tao Han; Weida Tong; Deborah K Hansen; James C Fuscoe; Ricky D Edmondson; Richard Beger; Yvonne P Dragan
An integrated study of acute effects of valproic acid in the liver using metabonomics, proteomics, and transcriptomics platforms.
Omics : a journal of integrative biology 2006;10(1):1-14.
2006: Michael P Holsapple; Henri C Pitot; Samuel M Cohen; Samuel H Cohen; Alan R Boobis; James Klaunig; Timothy Pastoor; Vicki Dellarco; Yvonne P Dragan
Mode of action in relevance of rodent liver tumors to human cancer risk.
Toxicological sciences : an official journal of the Society of Toxicology 2006;89(1):51-6.
2005: H Fang; W Tong; R Perkins; L Shi; H Hong; X Cao; Q Xie; S H Yim; J M Ward; H C Pitot; Yvonne P Dragan
Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling.
BMC bioinformatics 2005;6 Suppl 2():S6.
2005: Huixiao Hong; Yvonne P Dragan; Joshua Epstein; Candee Teitel; Bangzheng Chen; Qian Xie; Hong Fang; Leming Shi; Roger Perkins; Weida Tong
Quality control and quality assessment of data from surface-enhanced laser desorption/ionization (SELDI) time-of flight (TOF) mass spectrometry (MS).
BMC bioinformatics 2005;6 Suppl 2():S5.
2004: Yvonne P Dragan; Linda M Sargent; Karlee Babcock; Nina Kinunen; Henry C Pitot
Alterations in specific gene expression and focal neoplastic growth during spontaneous hepatocarcinogenesis in albumin-SV40 T antigen transgenic rats.
Molecular carcinogenesis 2004;40(3):150-9.
2003: Sun Hee Yim; Jerrold M Ward; Yvonne P Dragan; Atsushi Yamada; Peter C Scacheri; Shioko Kimura; Frank J Gonzalez
Microarray analysis using amplified mRNA from laser capture microdissection of microscopic hepatocellular precancerous lesions and frozen hepatocellular carcinomas reveals unique and consistent gene expression profiles.
Toxicologic pathology 2003;31(3):295-303.
2001: Rao L Divi; Yvonne P Dragan; Henry C Pitot; Miriam C Poirier
Immunohistochemical localization and semi-quantitation of hepatic tamoxifen-DNA adducts in rats exposed orally to tamoxifen.
Carcinogenesis 2001;22(10):1693-9.
2000: Yvonne P Dragan; Raquel Valdés; M Gomez-Angelats; Antonio Felipe; F Javier Casado; Henry C Pitot; Marçal Pastor-Anglada
Selective loss of nucleoside carrier expression in rat hepatocarcinomas.
Hepatology (Baltimore, Md.) 2000;32(2):239-46.
2000: JG Teeguarden; Michael A Newton; Yvonne P Dragan; Henry C Pitot
Genome-wide loss of heterozygosity analysis of chemically induced rat hepatocellular carcinomas reveals elevated frequency of allelic imbalances on chromosomes 1, 6, 8, 11, 15, 17, and 20.
Molecular carcinogenesis 2000;28(1):51-61.
2000: Henry C Pitot; H Hikita; Yvonne P Dragan; L Sargent; M Haas
Review article: the stages of gastrointestinal carcinogenesis--application of rodent models to human disease.
Alimentary pharmacology & therapeutics 2000;14 Suppl 1():153-60.
2000: JG Teeguarden; Yvonne P Dragan; Henry C Pitot
Hazard assessment of chemical carcinogens: the impact of hormesis.
Journal of applied toxicology : JAT 2000;20(2):113-20.
2000: MJ Haas; Carol Sattler; Yvonne P Dragan; W L Gast; Henry C Pitot
Multiple polypeptide hormone expression in pancreatic islet cell carcinomas derived from phosphoenolpyruvatecarboxykinase-SV40 T antigen transgenic rats.
Pancreas 2000;20(2):206-14.
1999: JG Teeguarden; Yvonne P Dragan; J Singh; J Vaughan; Y H Xu; T Goldsworthy; Henry C Pitot
Quantitative analysis of dose- and time-dependent promotion of four phenotypes of altered hepatic foci by 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Sprague-Dawley rats.
Toxicological sciences : an official journal of the Society of Toxicology 1999;51(2):211-23.
1999: M Gómez-Angelats; JG Teeguarden; Yvonne P Dragan; Henry C Pitot
Mutational analysis of three tumor suppressor genes in two models of rat hepatocarcinogenesis.
Molecular carcinogenesis 1999;25(3):157-63.
1999: MJ Haas; Yvonne P Dragan; H Hikita; R Shimel; K Takimoto; S Heath; J Vaughan; Henry C Pitot
Transgene expression and repression in transgenic rats bearing the phosphoenolpyruvate carboxykinase-simian virus 40 T antigen or the phosphoenolpyruvate carboxykinase-transforming growth factor-alpha constructs.
The American journal of pathology 1999;155(1):183-92.
1998: E F Nuwaysir; Yvonne P Dragan; R McCague; P Martin; J Mann; V C Jordan; H C Pitot
Structure-activity relationships for triphenylethylene antiestrogens on hepatic phase-I and phase-II enzyme expression.
Biochemical pharmacology 1998;56(3):321-7.
1998: H Hikita; E F Nuwaysir; J Vaughan; Karlee Babcock; MJ Haas; Yvonne P Dragan; Henry C Pitot
The effect of short-term fasting, phenobarbital and refeeding on apoptotic loss, cell replication and gene expression in rat liver during the promotion stage.
Carcinogenesis 1998;19(8):1417-25.
1998: Yvonne P Dragan; R J Shimel; N Bahnub; G Sattler; J R Vaughan; V Craig Jordan; Henry C Pitot
Effect of chronic administration of mestranol, tamoxifen, and toremifene on hepatic ploidy in rats.
Toxicological sciences : an official journal of the Society of Toxicology 1998;43(2):129-38.
1998: JG Teeguarden; Yvonne P Dragan; Henry C Pitot
Implications of hormesis on the bioassay and hazard assessment of chemical carcinogens.
Human & experimental toxicology 1998;17(5):254-8.
1998: Yi-Hua Xu; Yvonne P Dragan; H A Campbell; Henry C Pitot
STEREO: a program on a PC-Windows 95 platform for recording and evaluating quantitative stereologic investigations of multistage hepatocarcinogenesis in rodents.
Computer methods and programs in biomedicine 1998;56(1):49-63.
1998: Yvonne P Dragan; J Klaunig; R Maronpot; T Goldsworthy
Mechanisms of susceptibility to mouse liver carcinogenesis.
Toxicological sciences : an official journal of the Society of Toxicology 1998;41(1):3-7.
1997: Linda M Sargent; Yvonne P Dragan; G Sattler; Y H Xu; J Wiley; Henry C Pitot
Specific chromosomal changes in albumin simian virus 40 T antigen transgenic rat liver neoplasms.
Cancer research 1997;57(16):3451-6.
1997: Yvonne P Dragan
Minisymposium on emerging methods in cancer hazard identification.
Toxicologic pathology 1997;25(2):238.
1997: Yvonne P Dragan; H A Campbell; X H Xu; Henry C Pitot
Quantitative stereological studies of a 'selection' protocol of hepatocarcinogenesis following initiation in neonatal male and female rats.
Carcinogenesis 1997;18(1):149-58.
1996: Yvonne P Dragan; J Singh; Henry C Pitot
Effect of the separate and combined administration of mestranol and phenobarbital on the development of altered hepatic foci expressing placental form of glutathione S-transferase in the rat.
Carcinogenesis 1996;17(9):2043-52.
1996: L Sargent; Yvonne P Dragan; K Babcock; J Wiley; J Klaunig; Henry C Pitot
Cytogenetic analysis of three rat liver epithelial cell lines (WBneo, WBHa-ras, and WBrasIIa) and correlation of an early chromosomal alteration with insulin-like growth factor II expression.
Cancer research 1996;56(13):2992-7.
1996: L Sargent; Yvonne P Dragan; Y H Xu; G Sattler; J Wiley; Henry C Pitot
Karyotypic changes in a multistage model of chemical hepatocarcinogenesis in the rat.
Cancer research 1996;56(13):2985-91.
1996: L M Sargent; Yvonne P Dragan; Carol Sattler; N Bahnub; G Sattler; P Martin; A Cisneros; J Mann; Snorri S Thorgeirsson; V C Jordan; Henry C Pitot
Induction of hepatic aneuploidy in vivo by tamoxifen, toremifene and idoxifene in female Sprague-Dawley rats.
Carcinogenesis 1996;17(5):1051-6.
1996: Yvonne P Dragan; S Fahey; E Nuwaysir; Carol Sattler; K Babcock; J Vaughan; R McCague; V C Jordan; Henry C Pitot
The effect of tamoxifen and two of its non-isomerizable fixed-ring analogs on multistage rat hepatocarcinogenesis.
Carcinogenesis 1996;17(3):585-94.
1996: Henry C Pitot; Yvonne P Dragan; JG Teeguarden; S Hsia; H Campbell
Quantitation of multistage carcinogenesis in rat liver.
Toxicologic pathology 1996;24(1):119-28.
1995: Yvonne P Dragan; J Hully; K Baker; R Crow; M J Mass; Henry C Pitot
Comparison of experimental and theoretical parameters of the Moolgavkar-Venzon-Knudson incidence function for the stages of initiation and promotion in rat hepatocarcinogenesis.
Toxicology 1995;102(1-2):161-75.
1995: Yvonne P Dragan; JG Teeguarden; H Campbell; S Hsia; Henry C Pitot
The quantitation of altered hepatic foci during multistage hepatocarcinogenesis in the rat: transforming growth factor alpha expression as a marker for the stage of progression.
Cancer letters 1995;93(1):73-83.
1995: E F Nuwaysir; Yvonne P Dragan; Colin R Jefcoate; V C Jordan; Henry C Pitot
Effects of tamoxifen administration on the expression of xenobiotic metabolizing enzymes in rat liver.
Cancer research 1995;55(8):1780-6.
1995: Henry C Pitot; Yvonne P Dragan
The instability of tumor promotion in relation to human cancer risk.
Progress in clinical and biological research 1995;391():21-38.
1994: Yvonne P Dragan; H A Campbell; K Baker; J Vaughan; M Mass; Henry C Pitot
Focal and non-focal hepatic expression of placental glutathione S-transferase in carcinogen-treated rats.
Carcinogenesis 1994;15(11):2587-91.
1994: Yvonne P Dragan; J Hully; R Crow; M Mass; Henry C Pitot
Incorporation of bromodeoxyuridine in glutathione S-transferase-positive hepatocytes during rat multistage hepatocarcinogenesis.
Carcinogenesis 1994;15(9):1939-47.
1994: J R Hully; Y Su; J K Lohse; Anne E Griep; Carol Sattler; MJ Haas; Yvonne P Dragan; J Peterson; M Neveu; Henry C Pitot
Transgenic hepatocarcinogenesis in the rat.
The American journal of pathology 1994;145(2):384-97.
1994: Yvonne P Dragan; J R Hully; Jun Nakamura; M J Mass; James A Swenberg; Henry C Pitot
Biochemical events during initiation of rat hepatocarcinogenesis.
Carcinogenesis 1994;15(7):1451-8.
1994: L M Sargent; Yvonne P Dragan; N Bahnub; J E Wiley; Carol Sattler; P Schroeder; G L Sattler; V C Jordan; Henry C Pitot
Tamoxifen induces hepatic aneuploidy and mitotic spindle disruption after a single in vivo administration to female Sprague-Dawley rats.
Cancer research 1994;54(13):3357-60.
1994: Henry C Pitot; Yvonne P Dragan
The multistage nature of chemically induced hepatocarcinogenesis in the rat.
Drug metabolism reviews 1994;26(1-2):209-20.
1994: Yvonne P Dragan; S Fahey; K Street; J Vaughan; V C Jordan; Henry C Pitot
Studies of tamoxifen as a promoter of hepatocarcinogenesis in female Fischer F344 rats.
Breast cancer research and treatment 1994;31(1):11-25.
1993: Yvonne P Dragan; J Peterson; Henry C Pitot
Comparison of hepatocyte phenotypes at the glutathione transferase and albumin loci in Sprague-Dawley and Nagase analbuminemic rats and F1 progeny after initiation and promotion.
Carcinogenesis 1993;14(7):1313-9.
1993: Yvonne P Dragan; Y H Xu; Henry C Pitot
The effect of the dose of diethylnitrosamine on the initiation of altered hepatic foci in neonatal female rats.
Carcinogenesis 1993;14(3):385-91.
1993: Yvonne P Dragan; C Laufer; A J Koleske; Norman R Drinkwater; Henry C Pitot
Quantitative comparison of initiation and mutation phenotypes in hepatocytes of the analbuminemic rat.
Japanese journal of cancer research : Gann 1993;84(2):175-83.
1993: Yvonne P Dragan; L Sargent; Y D Xu; Y H Xu; Henry C Pitot
The initiation-promotion-progression model of rat hepatocarcinogenesis.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1993;202(1):16-24.
1992: Yvonne P Dragan; X H Xu; T L Goldsworthy; H A Campbell; R R Maronpot; Henry C Pitot
Characterization of the promotion of altered hepatic foci by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the female rat.
Carcinogenesis 1992;13(8):1389-95.
1992: Yvonne P Dragan; Henry C Pitot
The role of the stages of initiation and promotion in phenotypic diversity during hepatocarcinogenesis in the rat.
Carcinogenesis 1992;13(5):739-50.
1992: Yvonne P Dragan; Henry C Pitot
Multistage hepatocarcinogenesis in the rat: insights into risk estimation.
Progress in clinical and biological research 1992;374():261-79.
1991: Y D Xu; Yvonne P Dragan; T Young; Henry C Pitot
The effect of the format of administration and the total dose of phenobarbital on altered hepatic foci following initiation in female rats with diethylnitrosamine.
Carcinogenesis 1991;12(6):1009-16.
1991: Henry C Pitot; Yvonne P Dragan; L Sargent; Y H Xu
Biochemical markers associated with the stages of promotion and progression during hepatocarcinogenesis in the rat.
Environmental health perspectives 1991;93():181-9.
1991: L Sargent; Yvonne P Dragan; C Erickson; C J Laufer; Henry C Pitot
Study of the separate and combined effects of the non-planar 2,5,2',5'- and the planar 3,4,3',4'-tetrachlorobiphenyl in liver and lymphocytes in vivo.
Carcinogenesis 1991;12(5):793-800.
1991: Yvonne P Dragan; T Rizvi; Y H Xu; J R Hully; N Bawa; H A Campbell; R R Maronpot; Henry C Pitot
An initiation-promotion assay in rat liver as a potential complement to the 2-year carcinogenesis bioassay.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1991;16(3):525-47.
1991: Henry C Pitot; Yvonne P Dragan; M J Neveu; T A Rizvi; J R Hully; H A Campbell
Chemicals, cell proliferation, risk estimation, and multistage carcinogenesis.
Progress in clinical and biological research 1991;369():517-32.
1991: Henry C Pitot; Yvonne P Dragan; Y H Xu; J Peterson; J Hully; H Campbell
Nakahara Memorial Lecture. Pathways of carcinogenesis--genetic and epigenetic.
Princess Takamatsu symposia 1991;22():21-33.
1991: Yvonne P Dragan; Y D Xu; Henry C Pitot
Tumor promotion as a target for estrogen/antiestrogen effects in rat hepatocarcinogenesis.
Preventive medicine 1991;20(1):15-26.
1990: Henry C Pitot; Yvonne P Dragan; Y H Xu; M Pyron; C Laufer; T Rizvi
Role of altered hepatic foci in the stages of carcinogenesis.
Progress in clinical and biological research 1990;340D():81-95.
1989: Henry C Pitot; H A Campbell; R Maronpot; N Bawa; T A Rizvi; Y H Xu; L Sargent; Yvonne P Dragan; M Pyron
Critical parameters in the quantitation of the stages of initiation, promotion, and progression in one model of hepatocarcinogenesis in the rat.
Toxicologic pathology 1989;17(4 Pt 1):594-611; discussion 611-2.