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Chris Drakeley

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Carla Proietti; Eleanor M Riley; R Ronca; W Stone; Federica Verra; M T Bretscher; Patrick H Corran; Andrea Crisanti; Chris Drakeley; Thomas G Egwang; B N Kanoi; Bruno Arcà; B Balikagala; T Bousema
Influence of infection on malaria-specific antibody dynamics in a cohort exposed to intense malaria transmission in northern Uganda.
Alice C Eziefula; Moses Kamya; Sarah G Staedke; Emily Webb; Nicholas J White; Shunmay Yeung; Teun Bousema; Chris Drakeley
Study protocol for a randomised controlled double-blinded trial of the dose-dependent efficacy and safety of primaquine for clearance of gametocytes in children with uncomplicated falciparum malaria in Uganda.
Teun Bousema; Amrish Baidjoe; Nabie Bayoh; Meghna Desai; Chris Drakeley; James T Griffin; Immo Kleinschmidt; Kayla Laserson; Edmond J Remarque; Robert Sauerwein; Jennifer Stevenson; Gillian Stresman; John M Vulule; Jonathan Cox
The impact of hotspot-targeted interventions on malaria transmission: study protocol for a cluster-randomized controlled trial.

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All Publications

2013: Carla Proietti; Eleanor M Riley; R Ronca; W Stone; Federica Verra; M T Bretscher; Patrick H Corran; Andrea Crisanti; Chris Drakeley; Thomas G Egwang; B N Kanoi; Bruno Arcà; B Balikagala; T Bousema
Influence of infection on malaria-specific antibody dynamics in a cohort exposed to intense malaria transmission in northern Uganda.
Parasite immunology 2013;35(5-6):164-73.
2013: Alice C Eziefula; Moses Kamya; Sarah G Staedke; Emily Webb; Nicholas J White; Shunmay Yeung; Teun Bousema; Chris Drakeley
Study protocol for a randomised controlled double-blinded trial of the dose-dependent efficacy and safety of primaquine for clearance of gametocytes in children with uncomplicated falciparum malaria in Uganda.
BMJ open 2013;3(3):.
2013: Teun Bousema; Amrish Baidjoe; Nabie Bayoh; Meghna Desai; Chris Drakeley; James T Griffin; Immo Kleinschmidt; Kayla Laserson; Edmond J Remarque; Robert Sauerwein; Jennifer Stevenson; Gillian Stresman; John M Vulule; Jonathan Cox
The impact of hotspot-targeted interventions on malaria transmission: study protocol for a cluster-randomized controlled trial.
Trials 2013;14():36.
2013: Michael T Bretscher; Jackie Cook; William A Hawley; Neil F Lobo; Dian Nugraheni; Supargiyono Supargiyono; Anis N Widyastuti; Mahardika A Wijayanti; Chris Drakeley
Measurement of Plasmodium falciparum transmission intensity using serological cohort data from Indonesian schoolchildren.
Malaria journal 2013;12():21.
2012: Amir Horowitz; Elizabeth King; Amanda Leach; John P A Lusingu; Philippe Moris; Philip Bejon; Joe Cohen; Patrick H Corran; Denise Dekker; Chris Drakeley; Julius Hafalla; Johan Vekemans; Tonya Villafana; Lorenz Von Seidlein; Eleanor M Riley
Antigen-specific IL-2 secretion correlates with NK cell responses after immunization of Tanzanian children with the RTS,S/AS01 malaria vaccine.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(10):5054-62.
2012: Alphaxard Manjurano; Caroline Maxwell; George Mtove; Behzad Nadjm; Raimos Olomi; Hugh Reyburn; Eleanor M Riley; Kirk R Rockett; Nuno Sepulveda; Hannah Wangai; Susana G Campino; Taane G Clark; Anna Jeffreys; Chris Drakeley
Candidate human genetic polymorphisms and severe malaria in a Tanzanian population.
PloS one 2012;7(10):e47463.
2012: Alice C Eziefula; Roly Gosling; Michelle S Hsiang; Jimee Hwang; Lorenz Von Seidlein; Teun Bousema; Chris Drakeley
Rationale for short course primaquine in Africa to interrupt malaria transmission.
Malaria journal 2012;11():360.
2012: Teun Bousema; Parfait Awono-Ambene; Ashley Birkett; Sarah Bonnet; Mamadou Coulibaly; Mouctar Diallo; Rhoel R Dinglasan; Ogobara Doumbo; Chris Drakeley; Louis C Gouagna; Patricia M Graves; Emily Locke; Merribeth Morin; Isabelle Morlais; Bert Mulder; Vincent Robert; Will Roeffen; Robert Sauerwein; Colin Sutherland; Geoffrey A T Targett; Timoléon Tchuinkam; Yeya T Touré; Travis van Warmerdam; Yimin Wu; Thomas S Churcher
Mosquito feeding assays to determine the infectiousness of naturally infected Plasmodium falciparum gametocyte carriers.
PloS one 2012;7(8):e42821.
2012: Sophie Jones; Robert W Sauerwein; Colin J Sutherland; Karina Teelen; Marga van der Vegte-Bolmer; Patrick H Corran; Chris Drakeley; Rachel Hallett; Cornelus C Hermsen; Theo Arens; Teun Bousema
Filter paper collection of Plasmodium falciparum mRNA for detecting low-density gametocytes.
Malaria journal 2012;11():266.
2012: Anthony W Solomon; J Russell Stothard; Hu Wei; A Lee Willingham; Xiao-Nong Zhou; Mohamed Rhajaoui; W Evan Secor; Robin L Bailey; Isobel M Blake; Simon Brooker; Jun-Hu Chen; Jia-Xu Chen; Thomas S Churcher; Chris Drakeley; Tansy Edwards; Dirk Engels; Alan Fenwick; Michael French; Albis-Francesco Gabrielli; Nicholas C Grassly; Emma M Harding-Esch; Martin J Holland; Artemis Koukounari; Patrick J Lammie; Jacqueline Leslie; David C W Mabey; Rosanna W Peeling
A diagnostics platform for the integrated mapping, monitoring, and surveillance of neglected tropical diseases: rationale and target product profiles.
PLoS neglected tropical diseases 2012;6(7):e1746.
2012: Will Stone; Thor G Theander; Bruno Arcà; Teun Bousema; Ilona Carneiro; Daniel Chandramohan; Samwel Gesase; Roly D Gosling; Rhamadhan Hashim; Sophie Jones; David Modiano; Raffaele Ronca; Chris Drakeley
IgG responses to Anopheles gambiae salivary antigen gSG6 detect variation in exposure to malaria vectors and disease risk.
PloS one 2012;7(6):e40170.
2012: Ally Olotu; Juliana Wambua; Chris Drakeley; Greg Fegan; Kevin Marsh; George Nyangweso; Edna Ogada; Philip Bejon
Estimating individual exposure to malaria using local prevalence of malaria infection in the field.
PloS one 2012;7(3):e32929.
2012: Teun Bousema; Thomas S Churcher; Chris Drakeley; Azra C Ghani; James T Griffin; Robert W Sauerwein; David L Smith; Willem Takken; Roly Gosling
Hitting hotspots: spatial targeting of malaria for control and elimination.
PLoS medicine 2012;9(1):e1001165.
2011: Philip Bejon; Jackie Cook; Elke Bergmann-Leitner; Ally Olotu; John P A Lusingu; Jedidah Mwacharo; Johan Vekemans; Patricia Njuguna; Amanda Leach; Marc Lievens; Sheetij Dutta; Lorenz Von Seidlein; Barbara Savarese; Tonya Villafana; Martha M Lemnge; Joe Cohen; Kevin Marsh; Patrick H Corran; Evelina Angov; Eleanor M Riley; Chris Drakeley
Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children.
The Journal of infectious diseases 2011;204(1):9-18.
2011: Carla Proietti; Davide D Pettinato; Bernard N Kanoi; Edward Ntege; Andrea Crisanti; Eleanor M Riley; Thomas G Egwang; Chris Drakeley; Teun Bousema
Continuing intense malaria transmission in northern Uganda.
The American journal of tropical medicine and hygiene 2011;84(5):830-7.
2011: Teun Bousema; Chris Drakeley
Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination.
Clinical microbiology reviews 2011;24(2):377-410.
2011: Teun Bousema; Colin J Sutherland; Thomas S Churcher; Bert Mulder; Louis C Gouagna; Eleanor M Riley; Geoffrey A T Targett; Chris Drakeley
Human immune responses that reduce the transmission of Plasmodium falciparum in African populations.
International journal for parasitology 2011;41(3-4):293-300.
2011: Ally Olotu; John P A Lusingu; Amanda Leach; Marc Lievens; Johan Vekemans; Salum Msham; Trudie Lang; Jayne Gould; Marie-Claude Dubois; Erik Jongert; Preeti Vansadia; Terrell Carter; Patricia Njuguna; Ken O Awuondo; Anangisye Malabeja; Omar Abdul; Samwel Gesase; Neema Mturi; Chris Drakeley; Barbara Savarese; Tonya Villafana; Didier Lapierre; W Ripley Ballou; Joe Cohen; Martha M Lemnge; Norbert Peshu; Kevin Marsh; Eleanor M Riley; Lorenz Von Seidlein; Philip Bejon
Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5-17 months in Kenya and Tanzania: a randomised controlled trial.
The Lancet infectious diseases 2011;11(2):102-9.
2011: Alphaxard Manjurano; Lucy Okell; Raimos Olomi; Hugh Reyburn; Eleanor M Riley; Cally Roper; Taane G Clark; Sarah Joseph; Tedson Lukindo; Chris Drakeley
Association of sub-microscopic malaria parasite carriage with transmission intensity in north-eastern Tanzania.
Malaria journal 2011;10():370.
2011: Jackie Cook; Patrick H Corran; Teun Bousema; Immo Kleinschmidt; Gloria Nseng; Eleanor M Riley; Christopher Schwabe; Chris Drakeley
Serological markers suggest heterogeneity of effectiveness of malaria control interventions on Bioko Island, equatorial Guinea.
PloS one 2011;6(9):e25137.
2011: Seif A Shekalaghe; Karina Teelen; Roel ter Braak; Wouter van den Bijllaardt; Sven van den Bosch; Chris Drakeley; Roly Gosling; Rob Hermsen; Alutu Masokoto; Frank Mosha; Charles Mwanziva; Lucy Okell; Robert Sauerwein; Salimu Semvua; Teun Bousema
A cluster-randomized trial of mass drug administration with a gametocytocidal drug combination to interrupt malaria transmission in a low endemic area in Tanzania.
Malaria journal 2011;10():247.
2011: Patricia Tabernero Estévez; Davis C Nwakanma; Judith Sedaminou Satoguina; Sheila K West; David J Conway; Chris Drakeley
Human saliva as a source of anti-malarial antibodies to examine population exposure to Plasmodium falciparum.
Malaria journal 2011;10():104.
2010: Teun Bousema; Chris Drakeley; Samwel Gesase; Ramadhan Hashim; Stephen M Magesa; Frank Mosha; Silas Otieno; Ilona Carneiro; Jonathan Cox; Eliapendavyo Msuya; Immo Kleinschmidt; Caroline Maxwell; Brian Greenwood; Eleanor Riley; Robert W Sauerwein; Daniel Chandramohan; Roly D Gosling
Identification of hot spots of malaria transmission for targeted malaria control.
The Journal of infectious diseases 2010;201(11):1764-74.
2010: Seif A Shekalaghe; Roel ter Braak; Modibo Daou; Reginald Kavishe; Wouter van den Bijllaardt; Sven van den Bosch; Jan B Koenderink; Adrian J F Luty; Christopher J M Whitty; Chris Drakeley; Robert W Sauerwein; Teun Bousema
In Tanzania, hemolysis after a single dose of primaquine coadministered with an artemisinin is not restricted to glucose-6-phosphate dehydrogenase-deficient (G6PD A-) individuals.
Antimicrobial agents and chemotherapy 2010;54(5):1762-8.
2010: Teun Bousema; Randa M Youssef; Jackie Cook; Jonathan Cox; Victor A Alegana; Jamal Amran; Abdisalan M Noor; Robert W Snow; Chris Drakeley
Serologic markers for detecting malaria in areas of low endemicity, Somalia, 2008.
Emerging infectious diseases 2010;16(3):392-9.
2010: Samana Schwank; Colin J Sutherland; Chris Drakeley
Promiscuous expression of α-tubulin II in maturing male and female Plasmodium falciparum gametocytes.
PloS one 2010;5(12):e14470.
2010: Teun Bousema; Will Roeffen; Hinta Meijerink; Harry Mwerinde; Steve Mwakalinga; Geert-Jan van Gemert; Marga van de Vegte-Bolmer; Frank Mosha; Geoffrey A T Targett; Eleanor M Riley; Robert W Sauerwein; Chris Drakeley
The dynamics of naturally acquired immune responses to Plasmodium falciparum sexual stage antigens Pfs230 & Pfs48/45 in a low endemic area in Tanzania.
PloS one 2010;5(11):e14114.
2010: Jackie Cook; Heidi Reid; Jennifer Iavro; Melissa Kuwahata; George Taleo; Archie C A Clements; James McCarthy; Andrew Vallely; Chris Drakeley
Using serological measures to monitor changes in malaria transmission in Vanuatu.
Malaria journal 2010;9():169.
2010: Teun Bousema; Lucy Okell; Seif Shekalaghe; Jamie T Griffin; Sabah Omar; Patrick Sawa; Colin Sutherland; Robert W Sauerwein; Azra C Ghani; Chris Drakeley
Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs.
Malaria journal 2010;9():136.
2010: Neal Alexander; David Schellenberg; Billy Ngasala; Max Petzold; Chris Drakeley; Colin Sutherland
Assessing agreement between malaria slide density readings.
Malaria journal 2010;9():4.
2009: Lucy C Okell; Azra C Ghani; Emily Lyons; Chris Drakeley
Submicroscopic infection in Plasmodium falciparum-endemic populations: a systematic review and meta-analysis.
The Journal of infectious diseases 2009;200(10):1509-17.
2009: Chris Drakeley; Hugh Reyburn
Out with the old, in with the new: the utility of rapid diagnostic tests for malaria diagnosis in Africa.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2009;103(4):333-7.
2009: Judith Sedaminou Satoguina; Brigitte Walther; Chris Drakeley; Davis Nwakanma; Eniyou C Oriero; Simon Correa; Patrick Corran; David J Conway; Michael Walther
Comparison of surveillance methods applied to a situation of low malaria prevalence at rural sites in The Gambia and Guinea Bissau.
Malaria journal 2009;8():274.
2009: Geoffrey S Williams; Clement Mweya; LAVETA STEWART; George Mtove; Hugh Reyburn; Jackie Cook; Patrick H Corran; Eleanor M Riley; Chris Drakeley
Immunophoretic rapid diagnostic tests as a source of immunoglobulins for estimating malaria sero-prevalence and transmission intensity.
Malaria journal 2009;8():168.
2009: Chris Drakeley; Jackie Cook
Chapter 5. Potential contribution of sero-epidemiological analysis for monitoring malaria control and elimination: historical and current perspectives.
Advances in parasitology 2009;69():299-352.
2009: LAVETA STEWART; Roly D Gosling; Jamie Griffin; Samwel Gesase; Joseph Campo; Ramadan Hashim; Paul Masika; Jacklin Mosha; Teun Bousema; Seif Shekalaghe; Jackie Cook; Patrick H Corran; Azra C Ghani; Eleanor M Riley; Chris Drakeley
Rapid assessment of malaria transmission using age-specific sero-conversion rates.
PloS one 2009;4(6):e6083.
2009: Seif Shekalaghe; Michael Alifrangis; Charles Mwanziva; Anders Enevold; Steve Mwakalinga; Humphrey Mkali; Reginald Kavishe; Alphaxard Manjurano; Robert W Sauerwein; Chris Drakeley; Teun Bousema
Low density parasitaemia, red blood cell polymorphisms and Plasmodium falciparum specific immune responses in a low endemic area in northern Tanzania.
BMC infectious diseases 2009;9():69.
2009: Theonest K Mutabingwa; Kandi Muze; Rosalynn Ord; Marnie Briceño; Brian M Greenwood; Chris Drakeley; Christopher J M Whitty
Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania.
PloS one 2009;4(4):e5138.
2008: Lucy C Okell; Chris Drakeley; Teun Bousema; Christopher J M Whitty; Azra C Ghani
Modelling the impact of artemisinin combination therapy and long-acting treatments on malaria transmission intensity.
PLoS medicine 2008;5(11):e226; discussion e226.
2008: J Teun Bousema; Chris Drakeley; Petra Mens; Theo Arens; Rein Houben; Sabah A Omar; Louis C Gouagna; Henk Schallig; Robert W Sauerwein
Increased Plasmodium falciparum gametocyte production in mixed infections with P. malariae.
The American journal of tropical medicine and hygiene 2008;78(3):442-8.
2008: Roly D Gosling; Chris Drakeley; Daniel Chandramohan
Effective malaria control: better burden estimates needed.
Lancet 2008;371(9614):724.
2008: Charles Mwanziva; Seif Shekalaghe; Arnold Ndaro; Bianca Mengerink; Simon Megiroo; Frank Mosha; Robert W Sauerwein; Chris Drakeley; Roly Gosling; Teun Bousema
Overuse of artemisinin-combination therapy in Mto wa Mbu (river of mosquitoes), an area misinterpreted as high endemic for malaria.
Malaria journal 2008;7():232.
2008: Patrick H Corran; Jackie Cook; Caroline Lynch; Heleen Leendertse; Alphaxard Manjurano; Jamie Griffin; Jonathan Cox; Tarekegn A Abeku; Teun Bousema; Azra C Ghani; Chris Drakeley; Eleanor Riley
Dried blood spots as a source of anti-malarial antibodies for epidemiological studies.
Malaria journal 2008;7():195.
2008: Musa Jawara; Margaret Pinder; Chris Drakeley; Davis Nwakanma; Ebrima Jallow; Claus Bogh; Steven W Lindsay; David J Conway
Dry season ecology of Anopheles gambiae complex mosquitoes in The Gambia.
Malaria journal 2008;7():156.
2008: Roly D Gosling; Chris Drakeley; Alex Mwita; Daniel Chandramohan
Presumptive treatment of fever cases as malaria: help or hindrance for malaria control?
Malaria journal 2008;7():132.
2008: Lucy C Okell; Chris Drakeley; Azra C Ghani; Teun Bousema; Colin J Sutherland
Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials.
Malaria journal 2008;7():125.
2008: Maha Saeed; Will Roeffen; Neal Alexander; Chris Drakeley; Geoffrey A T Targett; Colin J Sutherland
Plasmodium falciparum antigens on the surface of the gametocyte-infected erythrocyte.
PloS one 2008;3(5):e2280.
2007: João A N Filipe; Eleanor M Riley; Chris Drakeley; Colin J Sutherland; Azra C Ghani
Determination of the processes driving the acquisition of immunity to malaria using a mathematical transmission model.
PLoS computational biology 2007;3(12):e255.
2007: Rosalynn Ord; Neal Alexander; Sam Dunyo; Rachel Hallett; Musa Jawara; Geoffrey A T Targett; Chris Drakeley; Colin J Sutherland
Seasonal carriage of pfcrt and pfmdr1 alleles in Gambian Plasmodium falciparum imply reduced fitness of chloroquine-resistant parasites.
The Journal of infectious diseases 2007;196(11):1613-9.
2007: Patrick H Corran; Paul Coleman; Eleanor Riley; Chris Drakeley
Serology: a robust indicator of malaria transmission intensity?
Trends in parasitology 2007;23(12):575-82.
2007: Manisha A Kulkarni; Robert Malima; Frank Mosha; Shandala Msangi; Ezra Mrema; Bilali Kabula; Boniface Lawrence; Safari Kinung'hi; John Swilla; William Kisinza; Manfred E Rau; Jane E Miller; Joanna Armstrong Schellenberg; Caroline Maxwell; Mark Rowland; Stephen M Magesa; Chris Drakeley
Efficacy of pyrethroid-treated nets against malaria vectors and nuisance-biting mosquitoes in Tanzania in areas with long-term insecticide-treated net use.
Tropical medicine & international health : TM & IH 2007;12(9):1061-73.
2007: Anders Enevold; Michael Alifrangis; Juan J Sanchez; Ilona Carneiro; Cally Roper; Claus Børsting; John P A Lusingu; Lasse S Vestergaard; Martha M Lemnge; Niels Morling; Eleanor Riley; Chris Drakeley
Associations between alpha+-thalassemia and Plasmodium falciparum malarial infection in northeastern Tanzania.
The Journal of infectious diseases 2007;196(3):451-9.
2007: J Teun Bousema; Chris Drakeley; Japheth Kihonda; Jan C M Hendriks; N I J Akim; Will Roeffen; Robert W Sauerwein
A longitudinal study of immune responses to Plasmodium falciparum sexual stage antigens in Tanzanian adults.
Parasite immunology 2007;29(6):309-17.
2007: Seif A Shekalaghe; J Teun Bousema; Karaine K Kunei; Paminus Lushino; Alutu Masokoto; Liselotte R Wolters; Steve Mwakalinga; Frank Mosha; Robert W Sauerwein; Chris Drakeley
Submicroscopic Plasmodium falciparum gametocyte carriage is common in an area of low and seasonal transmission in Tanzania.
Tropical medicine & international health : TM & IH 2007;12(4):547-53.
2007: Hugh Reyburn; Hilda Mbakilwa; Rose Mwangi; Ombeni Mwerinde; Raimos Olomi; Chris Drakeley; Christopher J M Whitty
Rapid diagnostic tests compared with malaria microscopy for guiding outpatient treatment of febrile illness in Tanzania: randomised trial.
BMJ (Clinical research ed.) 2007;334(7590):403.
2007: Colin J Sutherland; Chris Drakeley; David Schellenberg
How is childhood development of immunity to Plasmodium falciparum enhanced by certain antimalarial interventions?
Malaria journal 2007;6():161.
2007: Seif Shekalaghe; Chris Drakeley; Roly Gosling; Arnold Ndaro; Monique van Meegeren; Anders Enevold; Michael Alifrangis; Frank Mosha; Robert W Sauerwein; Teun Bousema
Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulphadoxine-pyrimethamine and artesunate.
PloS one 2007;2(10):e1023.
2007: Ilona Carneiro; Chris Drakeley; Seth Owusu-Agyei; Bruno P Mmbando; Daniel Chandramohan
Haemoglobin and haematocrit: is the threefold conversion valid for assessing anaemia in malaria-endemic settings?
Malaria journal 2007;6():67.
2006: Chris Drakeley; Colin Sutherland; J Teun Bousema; Robert W Sauerwein; Geoffrey A T Targett
The epidemiology of Plasmodium falciparum gametocytes: weapons of mass dispersion.
Trends in parasitology 2006;22(9):424-30.
2006: Ilona Carneiro; Thomas Smith; John P A Lusingu; Robert Malima; Jürg Utzinger; Chris Drakeley
Modeling the relationship between the population prevalence of Plasmodium falciparum malaria and anemia.
The American journal of tropical medicine and hygiene 2006;75(2 Suppl):82-9.
2006: Clare I R Chandler; Chris Drakeley; Hugh Reyburn; Ilona Carneiro
The effect of altitude on parasite density case definitions for malaria in northeastern Tanzania.
Tropical medicine & international health : TM & IH 2006;11(8):1178-84.
2006: Manisha A Kulkarni; Eliningaya Kweka; E Nyale; E Lyatuu; Frank Mosha; Daniel Chandramohan; Manfred E Rau; Chris Drakeley
Entomological evaluation of malaria vectors at different altitudes in Hai district, northeastern Tanzania.
Journal of medical entomology 2006;43(3):580-8.
2006: Chris Drakeley; J Teun Bousema; N I J Akim; Karina Teelen; Will Roeffen; AH Lensen; M Bolmer; Wijnand Eling; Robert W Sauerwein
Transmission-reducing immunity is inversely related to age in Plasmodium falciparum gametocyte carriers.
Parasite immunology 2006;28(5):185-90.
2006: J Teun Bousema; Petra Schneider; Louis C Gouagna; Chris Drakeley; Alma Tostmann; Rein Houben; John I Githure; Rosalynn Ord; Colin J Sutherland; Sabah A Omar; Robert W Sauerwein
Moderate effect of artemisinin-based combination therapy on transmission of Plasmodium falciparum.
The Journal of infectious diseases 2006;193(8):1151-9.
2006: J Teun Bousema; Chris Drakeley; Robert W Sauerwein
Sexual-stage antibody responses to P. falciparum in endemic populations.
Current molecular medicine 2006;6(2):223-9.
2006: Gerry F Killeen; Japheth Kihonda; Edith Lyimo; Fred R Oketch; Maya E Kotas; Evan M Mathenge; Joanna Armstrong Schellenberg; Christian Lengeler; Thomas A Smith; Chris Drakeley
Quantifying behavioural interactions between humans and mosquitoes: evaluating the protective efficacy of insecticidal nets against malaria transmission in rural Tanzania.
BMC infectious diseases 2006;6():161.
2006: M J A M Oesterholt; J Teun Bousema; O K Mwerinde; C Harris; P Lushino; A Masokoto; H Mwerinde; Frank Mosha; Chris Drakeley
Spatial and temporal variation in malaria transmission in a low endemicity area in northern Tanzania.
Malaria journal 2006;5():98.
2006: Manisha A Kulkarni; Mark Rowland; Michael Alifrangis; Frank Mosha; Johnson Matowo; Robert Malima; Justin Peter; Eliningaya Kweka; Issa Lyimo; Stephen M Magesa; Ali Salanti; Manfred E Rau; Chris Drakeley
Occurrence of the leucine-to-phenylalanine knockdown resistance (kdr) mutation in Anopheles arabiensis populations in Tanzania, detected by a simplified high-throughput SSOP-ELISA method.
Malaria journal 2006;5():56.
2006: Hugh Reyburn; John Ruanda; Ombeni Mwerinde; Chris Drakeley
The contribution of microscopy to targeting antimalarial treatment in a low transmission area of Tanzania.
Malaria journal 2006;5():4.
2006: Jon Eric Tongren; Chris Drakeley; Suzanna L R McDonald; Hugh G Reyburn; Alphaxard Manjurano; Watoky M M M Nkya; Martha M Lemnge; Channe D Gowda; Jim Todd; Patrick H Corran; Eleanor M Riley
Target antigen, age, and duration of antigen exposure independently regulate immunoglobulin G subclass switching in malaria.
Infection and immunity 2006;74(1):257-64.
2005: Chris Drakeley; Roly Gosling; Hugh Reyburn
Malaria diagnosis and treatment: one size does not fit all.
PLoS medicine 2005;2(6):e156; author reply e165.
2005: Chris Drakeley; Ilona Carneiro; Hugh Reyburn; Robert Malima; John P A Lusingu; Jonathan Cox; Thor G Theander; Watoky M M M Nkya; Martha M Lemnge; Eleanor M Riley
Altitude-dependent and -independent variations in Plasmodium falciparum prevalence in northeastern Tanzania.
The Journal of infectious diseases 2005;191(10):1589-98.
2005: Theonest K Mutabingwa; Devota Anthony; Archie Heller; Rachel Hallett; Jalal Ahmed; Chris Drakeley; Brian M Greenwood; Christopher J M Whitty
Amodiaquine alone, amodiaquine+sulfadoxine-pyrimethamine, amodiaquine+artesunate, and artemether-lumefantrine for outpatient treatment of malaria in Tanzanian children: a four-arm randomised effectiveness trial.
Lancet 2005;365(9469):1474-80.
2005: Chris Drakeley; Patrick H Corran; Paul G Coleman; Jon Eric Tongren; S L R McDonald; Ilona Carneiro; Robert Malima; John P A Lusingu; A Manjurano; Watoky M M M Nkya; Martha M Lemnge; Jonathan Cox; Hugh Reyburn; Eleanor M Riley
Estimating medium- and long-term trends in malaria transmission by using serological markers of malaria exposure.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(14):5108-13.
2005: Colin J Sutherland; Rosalynn Ord; Sam Dunyo; Musa Jawara; Chris Drakeley; Neal Alexander; Rosalind Coleman; Margaret Pinder; Gijs Walraven; Geoffrey A T Targett
Reduction of malaria transmission to Anopheles mosquitoes with a six-dose regimen of co-artemether.
PLoS medicine 2005;2(4):e92.
2005: Hugh Reyburn; Redepmta Mbatia; Chris Drakeley; Jane Bruce; Ilona Carneiro; Raimos Olomi; Jonathan Cox; Watoky M M M Nkya; Martha M Lemnge; Brian M Greenwood; Eleanor M Riley
Association of transmission intensity and age with clinical manifestations and case fatality of severe Plasmodium falciparum malaria.
JAMA : the journal of the American Medical Association 2005;293(12):1461-70.
2005: Michael Alifrangis; Sonia Enosse; Richard Pearce; Chris Drakeley; Cally Roper; Insaf F Khalil; Watoky M M M Nkya; Anita M Rønn; Thor G Theander; Ib C Bygbjerg
A simple, high-throughput method to detect Plasmodium falciparum single nucleotide polymorphisms in the dihydrofolate reductase, dihydropteroate synthase, and P. falciparum chloroquine resistance transporter genes using polymerase chain reaction- and enzyme-linked immunosorbent assay-based technology.
The American journal of tropical medicine and hygiene 2005;72(2):155-62.
2005: Anders Enevold; Lasse S Vestergaard; John P A Lusingu; Chris Drakeley; Martha M Lemnge; Thor G Theander; Ib C Bygbjerg; Michael Alifrangis
Rapid screening for glucose-6-phosphate dehydrogenase deficiency and haemoglobin polymorphisms in Africa by a simple high-throughput SSOP-ELISA method.
Malaria journal 2005;4():61.
2004: Hugh Reyburn; Redepmta Mbatia; Chris Drakeley; Ilona Carneiro; Emmanuel Mwakasungula; Ombeni Mwerinde; Kapalala Saganda; John Shao; Andrew Y Kitua; Raimos Olomi; Brian M Greenwood; Christopher J M Whitty
Overdiagnosis of malaria in patients with severe febrile illness in Tanzania: a prospective study.
BMJ (Clinical research ed.) 2004;329(7476):1212.
2004: Rhoida Y Nganda; Chris Drakeley; Hugh Reyburn; Tanya Marchant
Knowledge of malaria influences the use of insecticide treated nets but not intermittent presumptive treatment by pregnant women in Tanzania.
Malaria journal 2004;3():42.
2004: Rachel Hallett; Colin J Sutherland; Neal Alexander; Rosalynn Ord; Musa Jawara; Chris Drakeley; Margaret Pinder; Gijs Walraven; Geoffrey A T Targett; Ali Alloueche
Combination therapy counteracts the enhanced transmission of drug-resistant malaria parasites to mosquitoes.
Antimicrobial agents and chemotherapy 2004;48(10):3940-3.
2004: John P A Lusingu; Lasse S Vestergaard; Bruno P Mmbando; Chris Drakeley; Caroline Jones; Jumaa A Akida; Zacharia X Savaeli; Andrew Y Kitua; Martha M Lemnge; Thor G Theander
Malaria morbidity and immunity among residents of villages with different Plasmodium falciparum transmission intensity in North-Eastern Tanzania.
Malaria journal 2004;3():26.
2004: J Teun Bousema; Louis C Gouagna; Chris Drakeley; Annemiek M Meutstege; Bernard A Okech; Ikupa N J Akim; John C Beier; John I Githure; Robert W Sauerwein
Plasmodium falciparum gametocyte carriage in asymptomatic children in western Kenya.
Malaria journal 2004;3():18.
2004: Chris Drakeley; Wijnand Eling; Karina Teelen; J Teun Bousema; Robert W Sauerwein; Brian M Greenwood; Geoffrey A T Targett
Parasite infectivity and immunity to Plasmodium falciparum gametocytes in Gambian children.
Parasite immunology 2004;26(4):159-65.
2004: Chris Drakeley; Musa Jawara; Geoffrey A T Targett; Gijs Walraven; Uche Obisike; Rosalind Coleman; Margaret Pinder; Colin J Sutherland
Addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children causes a significant but short-lived reduction in infectiousness for mosquitoes.
Tropical medicine & international health : TM & IH 2004;9(1):53-61.
2003: Chris Drakeley; David Schellenberg; Japheth Kihonda; Carla A Sousa; Ana Paula Arez; Dinora Lopes; J Lines; Hassan Mshinda; Christian Lengeler; Joanna R M Armstrong Schellenberg; Marcel Tanner; Pedro Alonso
An estimation of the entomological inoculation rate for Ifakara: a semi-urban area in a region of intense malaria transmission in Tanzania.
Tropical medicine & international health : TM & IH 2003;8(9):767-74.
2003: Colin J Sutherland; Chris Drakeley; Uche Obisike; Rosalind Coleman; Musa Jawara; Geoffrey A T Targett; Paul Milligan; Margaret Pinder; Gijs Walraven
The addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children delays, but does not prevent treatment failure.
The American journal of tropical medicine and hygiene 2003;69(1):19-25.
2003: Cally Roper; Richard Pearce; Barry Bredenkamp; Jonathan Gumede; Chris Drakeley; Frank Mosha; Daniel Chandramohan; Brian Sharp
Antifolate antimalarial resistance in southeast Africa: a population-based analysis.
Lancet 2003;361(9364):1174-81.
2003: Richard J Pearce; Chris Drakeley; Daniel Chandramohan; Frank Mosha; Cally Roper
Molecular determination of point mutation haplotypes in the dihydrofolate reductase and dihydropteroate synthase of Plasmodium falciparum in three districts of northern Tanzania.
Antimicrobial agents and chemotherapy 2003;47(4):1347-54.
2003: Lorenz Von Seidlein; Gijs Walraven; Paul Milligan; Neal Alexander; Fandingding Manneh; Jacqueline L Deen; Roz Coleman; Musa Jawara; Steven W Lindsay; Chris Drakeley; Sarah De Martin; Piero Olliaro; Steve Bennett; Maarten Schim van der Loeff; Kunle Okunoye; Geoffrey A T Targett; Keith P W J McAdam; Justin F Doherty; Brian M Greenwood; Margaret Pinder
The effect of mass administration of sulfadoxine-pyrimethamine combined with artesunate on malaria incidence: a double-blind, community-randomized, placebo-controlled trial in The Gambia.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2003;97(2):217-25.
2002: Colin J Sutherland; Ali Alloueche; Jill Curtis; Chris Drakeley; Rosalynn Ord; Manoj T Duraisingh; Brian M Greenwood; Margaret Pinder; david charles warhurst; Geoffrey A T Targett
Gambian children successfully treated with chloroquine can harbor and transmit Plasmodium falciparum gametocytes carrying resistance genes.
The American journal of tropical medicine and hygiene 2002;67(6):578-85.
2002: N I J Akim; Honorathy Urassa; Chris Drakeley; Robert W Sauerwein; Andrew Y Kitua
Immunity to the sexual stages of Plasmodium falciparum in mothers, neonates and infants subject to intense and perennial malarial transmission.
Annals of tropical medicine and parasitology 2002;96(7):735-7.
2002: David Schellenberg; Elizeus Kahigwa; Chris Drakeley; Athumani Malende; John Wigayi; Chris Msokame; John J Aponte; Marcel Tanner; Hassan Mshinda; Clara Menendez; Pedro L Alonso
The safety and efficacy of sulfadoxine-pyrimethamine, amodiaquine, and their combination in the treatment of uncomplicated Plasmodium falciparum malaria.
The American journal of tropical medicine and hygiene 2002;67(1):17-23.
2001: Lorenz Von Seidlein; Chris Drakeley; Brian Greenwood; Gijs Walraven; Geoffrey A T Targett
Risk factors for gametocyte carriage in Gambian children.
The American journal of tropical medicine and hygiene 2001;65(5):523-7.
2001: Geoffrey A T Targett; Chris Drakeley; Musa Jawara; Lorenz Von Seidlein; Rosalind Coleman; J Deen; Margaret Pinder; Tom Doherty; Colin Sutherland; Gijs Walraven; Paul Milligan
Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae.
The Journal of infectious diseases 2001;183(8):1254-9.
2000: ML Quiñones; Chris Drakeley; O Müller; JD Lines; M Haywood; Brian M Greenwood
Diversion of Anopheles gambiae from children to other hosts following exposure to permethrin-treated bednets.
Medical and veterinary entomology 2000;14(4):369-75.
2000: N I J Akim; Chris Drakeley; T Kingo; B Simon; K Senkoro; Robert W Sauerwein
Dynamics of P. falciparum gametocytemia in symptomatic patients in an area of intense perennial transmission in Tanzania.
The American journal of tropical medicine and hygiene 2000;63(3-4):199-203.
2000: Chris Drakeley; N I J Akim; Robert W Sauerwein; B M Greenwood; Geoffrey A T Targett
Estimates of the infectious reservoir of Plasmodium falciparum malaria in The Gambia and in Tanzania.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2000;94(5):472-6.
2000: Chris Drakeley; K Flobbe; Brian M Greenwood; Geoffrey A T Targett
Plasmodium falciparum gametocytes in Gambian adults.
Annals of tropical medicine and parasitology 2000;94(4):399-401.
1999: Chris Drakeley; Joanna R M Armstrong Schellenberg; Salim Abdulla; Christian Lengeler
Short report: lack of specificity of Beilstein test in detecting pyrethroid insecticide on coloured mosquito nets.
Tropical medicine & international health : TM & IH 1999;4(10):639-40.
1999: Wolfram G Metzger; M Haywood; Umberto D'Alessandro; Chris Drakeley; H Weiss; Kalifa Bojang; Geoffrey A T Targett; Brian M Greenwood
Serological responses of Gambian children to immunization with the malaria vaccine SPf66.
Parasite immunology 1999;21(7):335-40.
1999: Chris Drakeley; I Secka; S Correa; B M Greenwood; Geoffrey A T Targett
Host haematological factors influencing the transmission of Plasmodium falciparum gametocytes to Anopheles gambiae s.s. mosquitoes.
Tropical medicine & international health : TM & IH 1999;4(2):131-8.
1998: Chris Drakeley; L Mulder; Timoléon Tchuinkam; S Gupta; Robert W Sauerwein; Geoffrey A T Targett
Transmission-blocking effects of sera from malaria-exposed individuals on Plasmodium falciparum isolates from gametocyte carriers.
Parasitology 1998;116 ( Pt 5)():417-23.
1997: Lorenz Von Seidlein; Manoj T Duraisingh; Chris Drakeley; Robin Bailey; Brian M Greenwood; Margaret Pinder
Polymorphism of the Pfmdr1 gene and chloroquine resistance in Plasmodium falciparum in The Gambia.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1997;91(4):450-3.
1997: Manoj T Duraisingh; Chris Drakeley; O Muller; Robin Bailey; Georges Snounou; Geoffrey A T Targett; Brian M Greenwood; david charles warhurst
Evidence for selection for the tyrosine-86 allele of the pfmdr 1 gene of Plasmodium falciparum by chloroquine and amodiaquine.
Parasitology 1997;114 ( Pt 3)():205-11.
1996: Chris Drakeley; Manoj T Duraisingh; M Póvoa; David J Conway; Geoffrey A T Targett; David A Baker
Geographical distribution of a variant epitope of Pfs48/45, a Plasmodium falciparum transmission-blocking vaccine candidate.
Molecular and biochemical parasitology 1996;81(2):253-7.
1996: David A Baker; Chris Drakeley; C S Ong; A G Lulat; Brian M Greenwood; Geoffrey A T Targett
Humoral immune responses in Gambians to Pfs16, an immunodominant, Plasmodium falciparum integral membrane protein.
Parasite immunology 1996;18(10):527-33.
1996: O Müller; MB Van Hensbroek; Shabbar Jaffar; Chris Drakeley; C Okorie; D Joof; Margaret Pinder; Brian Greenwood
A randomized trial of chloroquine, amodiaquine and pyrimethamine-sulphadoxine in Gambian children with uncomplicated malaria.
Tropical medicine & international health : TM & IH 1996;1(1):124-32.
1995: S T Sadiq; K W Glasgow; Chris Drakeley; O Muller; Brian M Greenwood; David C W Mabey; Robin L Bailey
Effects of azithromycin on malariometric indices in The Gambia.
Lancet 1995;346(8979):881-2.
1995: Umberto D'Alessandro; Amanda Leach; Chris Drakeley; Steve Bennett; BO Olaleye; Greg Fegan; Musa Jawara; P Langerock; M O George; Geoffrey A T Targett
Efficacy trial of malaria vaccine SPf66 in Gambian infants.
Lancet 1995;346(8973):462-7.
1995: Amanda Leach; Chris Drakeley; Umberto D'Alessandro; Greg Fegan; Steve Bennett; W Ripley Ballou; Geoffrey A T Targett; Brian M Greenwood
A pilot safety and immunogenicity study of the malaria vaccine SPf66 in Gambian infants.
Parasite immunology 1995;17(8):441-4.