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Jan Drappatz

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Jan Drappatz; April Eichler; Kelly Elian; Robert M Fielding; Morris D Groves; Stephen Kelsey; Betty Lawrence; Christina A Meyers; Tom Mikkelsen; Steve Rosenfeld; John Sarantopoulos; David Schiff; Mona Shing; Xiaolin Wang; Andrew Brenner; Jean Paul Castaigne; Eric T Wong; Patrick Y Wen
Phase I study of GRN1005 in recurrent malignant glioma.
Jethro Hu; Nadia Salem; Jeffrey G Supko; Patrick Y Wen; Lauren E Abrey; Jan Drappatz; Camilo E Fadul; Fred Hochberg
A phase II trial of oral gimatecan for recurrent glioblastoma.
James L Rubenstein; Marc A Shuman; Ranjana Advani; Glenna Auerback; Tracy Batchelor; Soonmee Cha; Lingjing Chen; Jan Drappatz; Elizabeth Gerstner; James Hwang; Cigall Kadoch; Hendrikus Krouwer; Jing Li; Clifford Lowell; Pamela Munster; Lloyd E Damon
Multicenter phase 1 trial of intraventricular immunochemotherapy in recurrent CNS lymphoma.

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2013: Jan Drappatz; April Eichler; Kelly Elian; Robert M Fielding; Morris D Groves; Stephen Kelsey; Betty Lawrence; Christina A Meyers; Tom Mikkelsen; Steve Rosenfeld; John Sarantopoulos; David Schiff; Mona Shing; Xiaolin Wang; Andrew Brenner; Jean Paul Castaigne; Eric T Wong; Patrick Y Wen
Phase I study of GRN1005 in recurrent malignant glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013;19(6):1567-76.
2013: Jethro Hu; Nadia Salem; Jeffrey G Supko; Patrick Y Wen; Lauren E Abrey; Jan Drappatz; Camilo E Fadul; Fred Hochberg
A phase II trial of oral gimatecan for recurrent glioblastoma.
Journal of neuro-oncology 2013;111(3):347-53.
2013: James L Rubenstein; Marc A Shuman; Ranjana Advani; Glenna Auerback; Tracy Batchelor; Soonmee Cha; Lingjing Chen; Jan Drappatz; Elizabeth Gerstner; James Hwang; Cigall Kadoch; Hendrikus Krouwer; Jing Li; Clifford Lowell; Pamela Munster; Lloyd E Damon
Multicenter phase 1 trial of intraventricular immunochemotherapy in recurrent CNS lymphoma.
Blood 2013;121(5):745-51.
2013: Leena Gandhi; Jan Drappatz; Nikhil H Ramaiya; Gregory A Otterson
High-dose pemetrexed in combination with high-dose crizotinib for the treatment of refractory CNS metastases in ALK-rearranged non-small-cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2013;8(1):e3-5.
2013: Lakshmi Nayak; Antonio M P Omuro; Michael Prados; David A Reardon; Patrick Y Wen; Lauren E Abrey; Lisa M Deangelis; Jan Drappatz; Mark R Gilbert
Multicenter phase II study of rituximab and temozolomide in recurrent primary central nervous system lymphoma.
Leukemia & lymphoma 2013;54(1):58-61.
2012: Eudocia Q Lee; Victor A Levin; Frank Lieberman; Minesh Mehta; Michael D Prados; H Ian Robins; John J Wright; W K Alfred Yung; Lauren Abrey; Kenneth Aldape; Susan M Chang; Timothy F Cloughesy; Janet E Dancey; Lisa M DeAngelis; Jan Drappatz; Mark R Gilbert; John Kuhn; Kathleen R Lamborn; Patrick Y Wen
Phase I/II study of sorafenib in combination with temsirolimus for recurrent glioblastoma or gliosarcoma: North American Brain Tumor Consortium study 05-02.
Neuro-oncology 2012;14(12):1511-8.
2012: Eudocia Q Lee; Frank S Lieberman; Renee M McGovern; Michael D Prados; Vinay K Puduvalli; Joel M Reid; H Ian Robins; Matthew M Ames; Susan M Chang; Timothy F Cloughesy; Serena Desideri; Jan Drappatz; Igor Espinoza-Delgado; Mark R Gilbert; John G Kuhn; Kathleen R Lamborn; Andrew B Lassman; Jihong Xu; Xiabu Ye; W K Alfred Yung; Patrick Y Wen
Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(21):6032-9.
2012: Lakshmi Nayak; Andrew D Norden; Antonio M P Omuro; Jeremy D Rudnick; Jan Drappatz; Fabio M Iwamoto; Eudocia Quant Lee; Thomas J Kaley
Atypical and anaplastic meningiomas treated with bevacizumab.
Journal of neuro-oncology 2012;109(1):187-93.
2012: Jan Drappatz
Medical care of patients with brain tumors.
Continuum (Minneapolis, Minn.) 2012;18(2):275-94.
2012: Jan Drappatz; M Gerard; S A Grimm; S Hammond; D C Lafrankie; E Q Lee; A D Norden; Jeffrey J Raizer; S Ruland; D Schiff; S M Snodgrass; Tracy T Batchelor; Rameen Beroukhim; A S Chi; A S Ciampa; Lisa M Doherty; Patrick Y Wen
Phase I study of panobinostat in combination with bevacizumab for recurrent high-grade glioma.
Journal of neuro-oncology 2012;107(1):133-8.
2012: David A Reardon; John H Sampson; James J Vredenburgh; Patrick Y Wen; April Coan; Annick Desjardins; Jan Drappatz; Sridharan Gururangan; James E Herndon; Eric S Lipp; Roger E McLendon; Andrew D Norden; Julie A Norfleet; Katherine B Peters; Henry S Friedman
Phase II study of Gleevec® plus hydroxyurea (HU) in adults with progressive or recurrent meningioma.
Journal of neuro-oncology 2012;106(2):409-15.
2012: Alan A Moazzam; Ryan Y Kim; Jan Drappatz; Santosh Kesari
Chronic lymphocytic leukemia with central nervous system involvement: report of two cases with a comprehensive literature review.
Journal of neuro-oncology 2012;106(1):185-200.
2012: Andrew D Norden; Eudocia C Quant; Sandra Ruland; Shota Tanaka; Julia Bartolomeo; Rameen Beroukhim; Abigail S Ciampa; Lisa M Doherty; Jan Drappatz; Debra C Lafrankie; Patrick Y Wen
Safety of concurrent bevacizumab therapy and anticoagulation in glioma patients.
Journal of neuro-oncology 2012;106(1):121-5.
2011: Phioanh Leia Nghiemphu; Michael D Prados; H Ian Robins; Alejandro Torres-Trejo; Patrick Y Wen; Lauren E Abrey; Susan M Chang; Timothy F Cloughesy; Lisa M DeAngelis; Alexis Demopoulos; Jan Drappatz; Howard A Fine; Karen Fink; Santosh Kesari; Kathleen R Lamborn; Andrew B Lassman; Frank S Lieberman; Mark G Malkin; Minesh Mehta
A phase I trial of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma.
International journal of radiation oncology, biology, physics 2011;81(5):1422-7.
2011: C Lu-Emerson; A D Norden; E C Quant; S Ruland; Rameen Beroukhim; A S Ciampa; L M Doherty; Jan Drappatz; D C Lafrankie; Patrick Y Wen
Retrospective study of dasatinib for recurrent glioblastoma after bevacizumab failure.
Journal of neuro-oncology 2011;104(1):287-91.
2011: Geoffrey S Young; Jan Drappatz; Joshua D Lawson; Eric A Macklin; Andrew D Norden; Kian Setayesh; Patrick Y Wen; Santosh kesari
Longitudinal MRI evidence for decreased survival among periventricular glioblastoma.
Journal of neuro-oncology 2011;104(1):261-9.
2011: Elizabeth R Gerstner; April F Eichler; Scott R Plotkin; Jan Drappatz; Colin L Doyle; Lei Xu; Dan G Duda; Patrick Y Wen; Rakesh K Jain; Tracy T Batchelor
Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide.
Journal of neuro-oncology 2011;103(2):325-32.
2011: Laura L Horky; Edward M Hsiao; Stephanie E Weiss; Jan Drappatz; Victor H Gerbaudo
Dual phase FDG-PET imaging of brain metastases provides superior assessment of recurrence versus post-treatment necrosis.
Journal of neuro-oncology 2011;103(1):137-46.
2011: Paul J Kelly; Marc J Dinkin; Jan Drappatz; Kevin N O'Regan; Stephanie E Weiss
Unexpected late radiation neurotoxicity following bevacizumab use: a case series.
Journal of neuro-oncology 2011;102(3):485-90.
2011: Andrew D Norden; Jan Drappatz; Patrick Y Wen; Elizabeth B Claus
Survival among patients with primary central nervous system lymphoma, 1973-2004.
Journal of neuro-oncology 2011;101(3):487-93.
2010: Patrick Y Wen; Eudocia Quant; Jan Drappatz; Rameen Beroukhim; Andrew D Norden
Medical therapies for meningiomas.
Journal of neuro-oncology 2010;99(3):365-78.
2010: Jan Drappatz; Andrew D Norden; Eric T Wong; Lisa M Doherty; Debra C Lafrankie; Abigail Ciampa; Santosh kesari; Christine Sceppa; Mary Gerard; Phuong Phan; David Schiff; Tracy T Batchelor; Keith L Ligon; Geoffrey Young; Alona Muzikansky; Stephanie E Weiss; Patrick Y Wen
Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma.
International journal of radiation oncology, biology, physics 2010;78(1):85-90.
2010: Eudocia C Quant; Jan Drappatz; Patrick Y Wen; Andrew D Norden
Recurrent high-grade glioma.
Current treatment options in neurology 2010;12(4):321-33.
2010: Tracy T Batchelor; Dan G Duda; Emmanuelle di Tomaso; Marek Ancukiewicz; Scott R Plotkin; Elizabeth Gerstner; April F Eichler; Jan Drappatz; Fred H Hochberg; Thomas Benner; David N Louis; Kenneth S Cohen; Houng Chea; Alexis Exarhopoulos; Jay S Loeffler; Marsha A Moses; Percy Ivy; A Gregory Sorensen; Patrick Y Wen; Rakesh K Jain
Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(17):2817-23.
2010: Jong Woo Lee; Patrick Y Wen; Shelley Hurwitz; Peter Black; Santosh kesari; Jan Drappatz; Alexandra J Golby; William M Wells; Simon K Warfield; Ron Kikinis; Edward B Bromfield
Morphological characteristics of brain tumors causing seizures.
Archives of neurology 2010;67(3):336-42.
2010: Patrick Y Wen; Andrew D Norden; Jan Drappatz; Eudocia Quant
Response assessment challenges in clinical trials of gliomas.
Current oncology reports 2010;12(1):68-75.
2009: Patrick Y Wen; W K Alfred Yung; Kathleen R Lamborn; Andrew D Norden; Timothy F Cloughesy; Lauren E Abrey; Howard A Fine; Susan M Chang; H Ian Robins; Karen Fink; Lisa De Angelis; Minesh Mehta; Emmanuelle di Tomaso; Jan Drappatz; Santosh kesari; Keith L Ligon; Ken Aldape; Rakesh K Jain; Charles D Stiles; Merrill J Egorin; Michael D Prados
Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium study 01-08).
Neuro-oncology 2009;11(6):853-60.
2009: Andrew D Norden; Jan Drappatz; Patrick Y Wen
Antiangiogenic therapies for high-grade glioma.
Nature reviews. Neurology 2009;5(11):610-20.
2009: Eudocia C Quant; Andrew D Norden; Jan Drappatz; Alona Muzikansky; Lisa M Doherty; Debra Lafrankie; Abigail Ciampa; Santosh kesari; Patrick Y Wen
Role of a second chemotherapy in recurrent malignant glioma patients who progress on bevacizumab.
Neuro-oncology 2009;11(5):550-5.
2009: Andrew D Norden; Jan Drappatz; Patrick Y Wen
Advances in meningioma therapy.
Current neurology and neuroscience reports 2009;9(3):231-40.
2009: Jan Drappatz; Andrew D Norden; Patrick Y Wen
Therapeutic strategies for inhibiting invasion in glioblastoma.
Expert review of neurotherapeutics 2009;9(4):519-34.
2009: Andrew D Norden; Jan Drappatz; Alona Muzikansky; Karly David; Mary Gerard; M Brenna McNamara; Phuong Phan; Ainsley Ross; Santosh kesari; Patrick Y Wen
An exploratory survival analysis of anti-angiogenic therapy for recurrent malignant glioma.
Journal of neuro-oncology 2009;92(2):149-55.
2009: Andrew D Norden; Jan Drappatz; Abigail Slate Ciampa; Lisa M Doherty; Debra Conrad LaFrankie; Santosh kesari; Patrick Y Wen
Colon perforation during antiangiogenic therapy for malignant glioma.
Neuro-oncology 2009;11(1):92-5.
2009: Santosh kesari; David Schiff; Jan Drappatz; Debra LaFrankie; Lisa M Doherty; Eric A Macklin; Alona Muzikansky; Sandro Santagata; Keith L Ligon; Andrew D Norden; Abigail Ciampa; Joanna Bradshaw; Brenda Levy; Gospova Radakovic; Naren Ramakrishna; Peter Black; Patrick Y Wen
Phase II study of protracted daily temozolomide for low-grade gliomas in adults.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(1):330-7.
2008: Andrew D Norden; Jan Drappatz; Patrick Y Wen
Novel anti-angiogenic therapies for malignant gliomas.
Lancet neurology 2008;7(12):1152-60.
2008: Andrew D Norden; Jan Drappatz; Patrick Y Wen
Antiangiogenic therapy in malignant gliomas.
Current opinion in oncology 2008;20(6):652-61.
2008: Lynn-Kristin Bracht; Patrick Y Wen; Jeffrey A Meyerhardt; Matthew H Kulke; Jason L Hornick; Mark Redston; Debra Conrad LaFrankie; Peter M Black; Santosh kesari; Andrew Norden; Jan Drappatz
DNA repair enzyme expression and differential response to temozolomide in a patient with both glioblastoma and metastatic pancreatic neuroendocrine tumor.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(29):4843-4.
2008: F Stephen Hodi; Darryl A Oble; Jan Drappatz; Elsa F Velazquez; Nikhil Ramaiya; Naren Ramakrishna; Arthur L Day; Andrea Kruse; Suzanne Mac Rae; Axel Hoos; Martin Mihm
CTLA-4 blockade with ipilimumab induces significant clinical benefit in a female with melanoma metastases to the CNS.
Nature clinical practice. Oncology 2008;5(9):557-61.
2008: Santosh kesari; Serra Akar; Ali Saad; Jan Drappatz; Igor J Koralnik; Daniel J DeAngelo
Progressive multifocal leukoencephalopathy in a patient with relapsed acute myelogenous leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(22):3804-7.
2008: Santosh kesari; Jan Drappatz; Serra Akar; Jo-Anne Vergilio; Patrick Y Wen; Robert J Soiffer; Richard M Stone; Daniel J DeAngelo
Recurrent acute promyelocytic leukemia presenting as a sacral nerve root mass.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(19):3279-81.
2008: Santosh kesari; David Schiff; John W Henson; Alona Muzikansky; Debra C Gigas; Lisa M Doherty; Tracy T Batchelor; Janina A Longtine; Keith L Ligon; Susan Weaver; Andrea Laforme; Naren Ramakrishna; Peter Black; Jan Drappatz; Abigail Ciampa; Judah Folkman; Mark W Kieran; Patrick Y Wen
Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults.
Neuro-oncology 2008;10(3):300-8.
2008: Santosh kesari; Ryung S. Kim; Vassilios Markos; Jan Drappatz; Patrick Y Wen; Amy A Pruitt
Prognostic factors in adult brainstem gliomas: a multicenter, retrospective analysis of 101 cases.
Journal of neuro-oncology 2008;88(2):175-83.
2008: Serra Akar; Jan Drappatz; Liangge Hsu; Russell A Blinder; Peter Black; Santosh kesari
Hypertrophic olivary degeneration after resection of a cerebellar tumor.
Journal of neuro-oncology 2008;87(3):341-5.
2008: Jan Drappatz; S Akar; David C Fisher; M A Samuels; Santosh kesari
Imaging of Bing-Neel syndrome.
Neurology 2008;70(16):1364.
2008: Andrew D Norden; G S Young; K Setayesh; A Muzikansky; R Klufas; G L Ross; A S Ciampa; L G Ebbeling; B Levy; Jan Drappatz; Santosh kesari; Patrick Y Wen
Bevacizumab for recurrent malignant gliomas: efficacy, toxicity, and patterns of recurrence.
Neurology 2008;70(10):779-87.
2007: Jan Drappatz; David Schiff; Santosh kesari; Andrew D Norden; Patrick Y Wen
Medical management of brain tumor patients.
Neurologic clinics 2007;25(4):1035-71, ix.
2007: Michelle L Monje; Naren Ramakrishna; Geoffrey Young; Jan Drappatz; Lisa M Doherty; Patrick Y Wen; Santosh kesari
Durable response of a radiation-induced, high-grade cerebellar glioma to temozolomide.
Journal of neuro-oncology 2007;84(2):179-83.
2007: Jan Drappatz; Tracy T Batchelor
Leptomeningeal neoplasms.
Current treatment options in neurology 2007;9(4):283-93.
2007: Santosh kesari; David Schiff; Lisa M Doherty; Debra C Gigas; Tracy T Batchelor; Alona Muzikansky; Alison O'Neill; Jan Drappatz; Alice S Chen-Plotkin; Naren Ramakrishna; Stephanie E Weiss; Brenda Levy; Joanna Bradshaw; Jean Kracher; Andrea Laforme; Peter Black; Judah Folkman; Mark W Kieran; Patrick Y Wen
Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults.
Neuro-oncology 2007;9(3):354-63.
2007: M G Chheda; Jan Drappatz; Norton J Greenberger; Santosh kesari; S E Weiss; Debra C Gigas; Lisa M Doherty; Patrick Y Wen
Hepatitis B reactivation during glioblastoma treatment with temozolomide: a cautionary note.
Neurology 2007;68(12):955-6.
2007: Ozden Narin; Jan Drappatz; Lisa M Doherty; Patrick Y Wen; Santosh kesari
Cerebrospinal fluid spread of anaplastic glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(5):596-7.
2007: Andrew D Norden; Jan Drappatz; Patrick Y Wen
Targeted drug therapy for meningiomas.
Neurosurgical focus 2007;23(4):E12.
2007: Tracy T Batchelor; A Gregory Sorensen; Emmanuelle di Tomaso; Wei-Ting Zhang; Dan G Duda; Kenneth S Cohen; Kevin R Kozak; Daniel P Cahill; Poe-Jou Chen; Mingwang Zhu; Marek Ancukiewicz; Maciej M Mrugala; Scott Plotkin; Jan Drappatz; David N Louis; Percy Ivy; David T Scadden; Thomas Benner; Jay S Loeffler; Patrick Y Wen; Rakesh K Jain
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.
Cancer cell 2007;11(1):83-95.
2006: Patrick Y Wen; David Schiff; Santosh kesari; Jan Drappatz; Debra C Gigas; Lisa M Doherty
Medical management of patients with brain tumors.
Journal of neuro-oncology 2006;80(3):313-32.
2006: Jan Drappatz; Patrick Y Wen
Chemotherapy and targeted molecular therapies for brain metastases.
Expert review of neurotherapeutics 2006;6(10):1465-79.
2006: Patrick Y Wen; Jan Drappatz
Novel therapies for meningiomas.
Expert review of neurotherapeutics 2006;6(10):1447-64.
2006: Lisa M Doherty; Debra C Gigas; Santosh kesari; Jan Drappatz; Ryung S. Kim; J Zimmerman; L Ostrowsky; Patrick Y Wen
Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas.
Neurology 2006;67(1):156-8.
2006: Patrick Y Wen; Santosh kesari; Jan Drappatz
Malignant gliomas: strategies to increase the effectiveness of targeted molecular treatment.
Expert review of anticancer therapy 2006;6(5):733-54.
2004: Jan Drappatz; Tracy T Batchelor
Neurologic complications of plasma cell disorders.
Clinical lymphoma 2004;5(3):163-71.
2004: Jan Drappatz; Patrick Y Wen
Non-cytotoxic drugs as potential treatments for gliomas.
Current opinion in neurology 2004;17(6):663-73.