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Simon Drew

Research Profile

Chemicals & Drugs

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Alzheimer's Disease

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Publications

TOP 3
Vijaya Kenche; Colin L Masters; Izabela Zawisza; Wojciech Bal; Kevin J Barnham; Simon C Drew
Mixed Ligand Cu(2+) Complexes of a Model Therapeutic with Alzheimer's Amyloid-β Peptide and Monoamine Neurotransmitters.
Gojko Buncic; Simon C Drew; Anthony G Wedd; Jonathan M White; Zhiguang Xiao; Paul S Donnelly
Copper complexes of a novel non-innocent quadridentate ligand.
Simon C Drew; Cathryn L Haigh; Helen M J Klemm; Colin L Masters; Steven J Collins; Kevin J Barnham; Victoria A Lawson
Optical imaging detects apoptosis in the brain and peripheral organs of prion-infected mice.

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All Publications

2013: Vijaya Kenche; Colin L Masters; Izabela Zawisza; Wojciech Bal; Kevin J Barnham; Simon C Drew
Mixed Ligand Cu(2+) Complexes of a Model Therapeutic with Alzheimer's Amyloid-β Peptide and Monoamine Neurotransmitters.
Inorganic chemistry 2013;52(8):4303-18.
2012: Gojko Buncic; Simon C Drew; Anthony G Wedd; Jonathan M White; Zhiguang Xiao; Paul S Donnelly
Copper complexes of a novel non-innocent quadridentate ligand.
Chemical communications (Cambridge, England) 2012;48(20):2570-2.
2011: Simon C Drew; Cathryn L Haigh; Helen M J Klemm; Colin L Masters; Steven J Collins; Kevin J Barnham; Victoria A Lawson
Optical imaging detects apoptosis in the brain and peripheral organs of prion-infected mice.
Journal of neuropathology and experimental neurology 2011;70(2):143-50.
2011: Giuseppe D Ciccotosto; Deborah J Tew; Simon C Drew; Danielle G Smith; Timothy Johanssen; Varsha Lal; Tong-Lay Crystal Lau; Keyla Perez; Cyril C Curtain; John D Wade; Frances Separovic; Colin L Masters; Jeffrey P Smith; Kevin J Barnham; Roberto Cappai
Stereospecific interactions are necessary for Alzheimer disease amyloid-β toxicity.
Neurobiology of aging 2011;32(2):235-48.
2010: Simon C Drew; Colin L Masters; Kevin J Barnham
Alzheimer's Aβ peptides with disease-associated N-terminal modifications: influence of isomerisation, truncation and mutation on Cu2+ coordination.
PloS one 2010;5(12):e15875.
2009: Simon C Drew; Colin L Masters; Kevin J Barnham
Alanine-2 carbonyl is an oxygen ligand in Cu2+ coordination of Alzheimer's disease amyloid-beta peptide--relevance to N-terminally truncated forms.
Journal of the American Chemical Society 2009;131(25):8760-1.
2009: Cathryn L Haigh; Simon C Drew; Martin P Boland; Colin L Masters; Kevin J Barnham; Victoria A Lawson; Steven J Collins
Dominant roles of the polybasic proline motif and copper in the PrP23-89-mediated stress protection response.
Journal of cell science 2009;122(Pt 10):1518-28.
2009: Simon C Drew; Christopher J Noble; Colin L Masters; Graeme R Hanson; Kevin J Barnham
Pleomorphic copper coordination by Alzheimer's disease amyloid-beta peptide.
Journal of the American Chemical Society 2009;131(3):1195-207.
2008: Simon C Drew; Karrera Y Djoko; Lianyi Zhang; Melissa Koay; John F Boas; John R Pilbrow; Zhiguang Xiao; Kevin J Barnham; Anthony G Wedd
Electron paramagnetic resonance characterization of the copper-resistance protein PcoC from Escherichia coli.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2008;13(6):899-907.
2008: John F Boas; Simon C Drew; Cyril C Curtain
Applications of electron paramagnetic resonance to studies of neurological disease.
European biophysics journal : EBJ 2008;37(3):281-94.
2008: Simon C Drew; Kevin J Barnham
Biophysical investigations of the prion protein using electron paramagnetic resonance.
Methods in molecular biology (Clifton, N.J.) 2008;459():173-96.
2007: Aphrodite Caragounis; Tai Du; Gulay Filiz; Katrina M Laughton; Irene Volitakis; Robyn A Sharples; Robert A Cherny; Colin L Masters; Simon C Drew; Andrew Hill; Qiao-Xin Li; Peter J Crouch; Kevin J Barnham; Anthony R White
Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.
The Biochemical journal 2007;407(3):435-50.
2006: David P Smith; Danielle G Smith; Cyril C Curtain; John F Boas; John R Pilbrow; Giuseppe D Ciccotosto; Tong-Lay Crystal Lau; Deborah J Tew; Keyla Perez; John D Wade; Ashley I Bush; Simon C Drew; Frances Separovic; Colin L Masters; Roberto Cappai; Kevin J Barnham
Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge.
The Journal of biological chemistry 2006;281(22):15145-54.
2002: Maddalena Cross; Zhiguang Xiao; Estelle M Maes; Roman S Czernuszewicz; Simon C Drew; John R Pilbrow; Graham Neil George; Anthony G Wedd
Removal of a cysteine ligand from rubredoxin: assembly of Fe(2)S(2) and Fe(S-Cys)(3)(OH) centres.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2002;7(7-8):781-90.