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Kurt Drickamer

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Sarah A Graham; Stuart M Haslam; Paul G Hitchen; Aristotelis Antonopoulos; Anne Dell; Kurt Drickamer; Maureen E Taylor
Identification of neutrophil granule glycoproteins as Lewis(x)-containing ligands cleared by the scavenger receptor C-type lectin.
Zoi Pipirou; Alex S Powlesland; Imke Steffen; Stefan Pöhlmann; Maureen E Taylor; Kurt Drickamer
Mouse LSECtin as a model for a human Ebola virus receptor.
Hadar Feinberg; Maureen E Taylor; Nahid Razi; Ryan McBride; Yuriy A Knirel; Sarah A Graham; Kurt Drickamer; William I Weis
Structural basis for langerin recognition of diverse pathogen and mammalian glycans through a single binding site.

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All Publications

2011: Sarah A Graham; Stuart M Haslam; Paul G Hitchen; Aristotelis Antonopoulos; Anne Dell; Kurt Drickamer; Maureen E Taylor
Identification of neutrophil granule glycoproteins as Lewis(x)-containing ligands cleared by the scavenger receptor C-type lectin.
The Journal of biological chemistry 2011;286(27):24336-49.
2011: Zoi Pipirou; Alex S Powlesland; Imke Steffen; Stefan Pöhlmann; Maureen E Taylor; Kurt Drickamer
Mouse LSECtin as a model for a human Ebola virus receptor.
Glycobiology 2011;21(6):806-12.
2011: Hadar Feinberg; Maureen E Taylor; Nahid Razi; Ryan McBride; Yuriy A Knirel; Sarah A Graham; Kurt Drickamer; William I Weis
Structural basis for langerin recognition of diverse pathogen and mammalian glycans through a single binding site.
Journal of molecular biology 2011;405(4):1027-39.
2011: Alex S Powlesland; Maria Marcela Barrio; José Mordoh; Paul G Hitchen; Anne Dell; Kurt Drickamer; Maureen E Taylor
Glycoproteomic characterization of carriers of the CD15/Lewisx epitope on Hodgkin's Reed-Sternberg cells.
BMC biochemistry 2011;12():13.
2010: Peter J Coombs; Rebecca Harrison; Samantha Pemberton; Adrián Quintero-Martinez; Simon Parry; Stuart M Haslam; Anne Dell; Maureen E Taylor; Kurt Drickamer
Identification of novel contributions to high-affinity glycoprotein-receptor interactions using engineered ligands.
Journal of molecular biology 2010;396(3):685-96.
2009: Hadar Feinberg; Cynthia K W Tso; Maureen E Taylor; Kurt Drickamer; William I Weis
Segmented helical structure of the neck region of the glycan-binding receptor DC-SIGNR.
Journal of molecular biology 2009;394(4):613-20.
2009: Maureen E Taylor; Kurt Drickamer
Structural insights into what glycan arrays tell us about how glycan-binding proteins interact with their ligands.
Glycobiology 2009;19(11):1155-62.
2009: Alex S Powlesland; Paul G Hitchen; Simon Parry; Sarah A Graham; Maria Marcela Barrio; Maria Teresa Elola; José Mordoh; Anne Dell; Kurt Drickamer; Maureen E Taylor
Targeted glycoproteomic identification of cancer cell glycosylation.
Glycobiology 2009;19(8):899-909.
2009: Sarah A Graham; Sabine A F Jégouzo; Sheng Yan; Alex S Powlesland; Jacob P Brady; Maureen E Taylor; Kurt Drickamer
Prolectin, a glycan-binding receptor on dividing B cells in germinal centers.
The Journal of biological chemistry 2009;284(27):18537-44.
2009: Quan D Yu; Asa P Oldring; Alex S Powlesland; Cynthia K W Tso; Chunxuan Yang; Kurt Drickamer; Maureen E Taylor
Autonomous tetramerization domains in the glycan-binding receptors DC-SIGN and DC-SIGNR.
Journal of molecular biology 2009;387(5):1075-80.
2008: Alex S Powlesland; Tanja Fisch; Maureen E Taylor; David Smith; Bérangère Tissot; Anne Dell; Stefan Pöhlmann; Kurt Drickamer
A novel mechanism for LSECtin binding to Ebola virus surface glycoprotein through truncated glycans.
The Journal of biological chemistry 2008;283(1):593-602.
2007: Maureen E Taylor; Kurt Drickamer
Paradigms for glycan-binding receptors in cell adhesion.
Current opinion in cell biology 2007;19(5):572-7.
2007: Hadar Feinberg; Riccardo Castelli; Kurt Drickamer; Peter H Seeberger; William I Weis
Multiple modes of binding enhance the affinity of DC-SIGN for high mannose N-linked glycans found on viral glycoproteins.
The Journal of biological chemistry 2007;282(6):4202-9.
2007: María Teresa Elola; Mariana Isabel Capurro; María Marcela Barrio; Peter J Coombs; Maureen E Taylor; Kurt Drickamer; José Mordoh
Lewis x antigen mediates adhesion of human breast carcinoma cells to activated endothelium. Possible involvement of the endothelial scavenger receptor C-type lectin.
Breast cancer research and treatment 2007;101(2):161-74.
2006: Peter J Coombs; Maureen E Taylor; Kurt Drickamer
Two categories of mammalian galactose-binding receptors distinguished by glycan array profiling.
Glycobiology 2006;16(8):1C-7C.
2006: Alex S Powlesland; Eliot M Ward; Sumon K Sadhu; Yuan Guo; Maureen E Taylor; Kurt Drickamer
Widely divergent biochemical properties of the complete set of mouse DC-SIGN-related proteins.
The Journal of biological chemistry 2006;281(29):20440-9.
2006: Yuan Guo; Claire E Atkinson; Maureen E Taylor; Kurt Drickamer
All but the shortest polymorphic forms of the viral receptor DC-SIGNR assemble into stable homo- and heterotetramers.
The Journal of biological chemistry 2006;281(24):16794-8.
2006: Eliot M Ward; Nicola S Stambach; Kurt Drickamer; Maureen E Taylor
Polymorphisms in human langerin affect stability and sugar binding activity.
The Journal of biological chemistry 2006;281(22):15450-6.
2006: Catherine E Napper; Kurt Drickamer; Maureen E Taylor
Collagen binding by the mannose receptor mediated through the fibronectin type II domain.
The Biochemical journal 2006;395(3):579-86.
2006: Elena M Comelli; Steven R Head; Tim Gilmartin; Thomas Whisenant; Stuart M Haslam; Simon J North; Nyet Kui Wong; Takashi Kudo; Hisashi Narimatsu; Jeffrey D Esko; Kurt Drickamer; Anne Dell; James C Paulson
A focused microarray approach to functional glycomics: transcriptional regulation of the glycome.
Glycobiology 2006;16(2):117-31.
2005: Kurt Drickamer; Maureen E Taylor
Targeting diversity.
Nature structural & molecular biology 2005;12(10):830-1.
2005: Peter J Coombs; Sarah A Graham; Kurt Drickamer; Maureen E Taylor
Selective binding of the scavenger receptor C-type lectin to Lewisx trisaccharide and related glycan ligands.
The Journal of biological chemistry 2005;280(24):22993-9.
2005: Hadar Feinberg; Yuan Guo; Daniel A Mitchell; Kurt Drickamer; William I Weis
Extended neck regions stabilize tetramers of the receptors DC-SIGN and DC-SIGNR.
The Journal of biological chemistry 2005;280(2):1327-35.
2004: Yuan Guo; Hadar Feinberg; Edward Conroy; Daniel A Mitchell; Richard Alvarez; Ola Blixt; Maureen E Taylor; William I Weis; Kurt Drickamer
Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR.
Nature structural & molecular biology 2004;11(7):591-8.
2004: Denis Houzelstein; Isabelle R Gonçalves; Andrew J Fadden; Sukhvinder S Sidhu; Douglas N W Cooper; Kurt Drickamer; Hakon Leffler; Françoise Poirier
Phylogenetic analysis of the vertebrate galectin family.
Molecular biology and evolution 2004;21(7):1177-87.
2004: Russell Wallis; Jonathan M Shaw; Joost C M Uitdehaag; Ce-Belle Chen; Dawn Torgersen; Kurt Drickamer
Localization of the serine protease-binding sites in the collagen-like domain of mannose-binding protein: indirect effects of naturally occurring mutations on protease binding and activation.
The Journal of biological chemistry 2004;279(14):14065-73.
2003: Andrew J Fadden; Oliver J Holt; Kurt Drickamer
Molecular characterization of the rat Kupffer cell glycoprotein receptor.
Glycobiology 2003;13(7):529-37.
2003: Natacha Frison; Maureen E Taylor; Elizabeth J Soilleux; Marie-Thérèse Bousser; Roger Mayer; Michel Monsigny; Kurt Drickamer; Annie-Claude Roche
Oligolysine-based oligosaccharide clusters: selective recognition and endocytosis by the mannose receptor and dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin.
The Journal of biological chemistry 2003;278(26):23922-9.
2003: Hadar Feinberg; Joost C M Uitdehaag; Jason M Davies; Russell Wallis; Kurt Drickamer; William I Weis
Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2.
The EMBO journal 2003;22(10):2348-59.
2003: Maureen E Taylor; Kurt Drickamer
Structure-function analysis of C-type animal lectins.
Methods in enzymology 2003;363():3-16.
2003: Kurt Drickamer; Maureen E Taylor
Identification of lectins from genomic sequence data.
Methods in enzymology 2003;362():560-7.
2002: Samuel Bouyain; Nicholas J Silk; Gustáv Fabini; Kurt Drickamer
An endogenous Drosophila receptor for glycans bearing alpha 1,3-linked core fucose residues.
The Journal of biological chemistry 2002;277(25):22566-72.
2002: Kenneth K-S Ng; Anand R Kolatkar; Shaun Park-Snyder; Hadar Feinberg; Damon A Clark; Kurt Drickamer; William I Weis
Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
The Journal of biological chemistry 2002;277(18):16088-95.
2002: Kurt Drickamer; Andrew J Fadden
Genomic analysis of C-type lectins.
Biochemical Society symposium 2002;(69):59-72.
2002: Kurt Drickamer; Maureen E Taylor
Glycan arrays for functional glycomics.
Genome biology 2002;3(12):REVIEWS1034.
2001: Hadar Feinberg; Daniel A Mitchell; Kurt Drickamer; William I Weis
Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR.
Science (New York, N.Y.) 2001;294(5549):2163-6.
2001: Samuel Bouyain; S Rushton; Kurt Drickamer
Minimal requirements for the binding of selectin ligands to a C-type carbohydrate-recognition domain.
Glycobiology 2001;11(11):989-96.
2001: Daniel A Mitchell; Andrew J Fadden; Kurt Drickamer
A novel mechanism of carbohydrate recognition by the C-type lectins DC-SIGN and DC-SIGNR. Subunit organization and binding to multivalent ligands.
The Journal of biological chemistry 2001;276(31):28939-45.
2001: RB Dodd; Kurt Drickamer
Lectin-like proteins in model organisms: implications for evolution of carbohydrate-binding activity.
Glycobiology 2001;11(5):71R-9R.
2000: Hadar Feinberg; Dawn Torgersen; Kurt Drickamer; William I Weis
Mechanism of pH-dependent N-acetylgalactosamine binding by a functional mimic of the hepatocyte asialoglycoprotein receptor.
The Journal of biological chemistry 2000;275(45):35176-84.
1999: S Wragg; Kurt Drickamer
Identification of amino acid residues that determine pH dependence of ligand binding to the asialoglycoprotein receptor during endocytosis.
The Journal of biological chemistry 1999;274(50):35400-6.
1999: Kurt Drickamer; RB Dodd
C-Type lectin-like domains in Caenorhabditis elegans: predictions from the complete genome sequence.
Glycobiology 1999;9(12):1357-69.
1999: Kurt Drickamer
C-type lectin-like domains.
Current opinion in structural biology 1999;9(5):585-90.
1999: Russell Wallis; Kurt Drickamer
Molecular determinants of oligomer formation and complement fixation in mannose-binding proteins.
The Journal of biological chemistry 1999;274(6):3580-9.
1998: Kurt Drickamer; Maureen E Taylor
Evolving views of protein glycosylation.
Trends in biochemical sciences 1998;23(9):321-4.
1998: Anand R Kolatkar; Leung Anthony; Rainer Isecke; Reinhard Brossmer; Kurt Drickamer; William I Weis
Mechanism of N-acetylgalactosamine binding to a C-type animal lectin carbohydrate-recognition domain.
The Journal of biological chemistry 1998;273(31):19502-8.
1998: William I Weis; Maureen E Taylor; Kurt Drickamer
The C-type lectin superfamily in the immune system.
Immunological reviews 1998;163():19-34.
1998: Dawn Torgersen; NP Mullin; Kurt Drickamer
Mechanism of ligand binding to E- and P-selectin analyzed using selectin/mannose-binding protein chimeras.
The Journal of biological chemistry 1998;273(11):6254-61.
1997: Russell Wallis; Kurt Drickamer
Asymmetry adjacent to the collagen-like domain in rat liver mannose-binding protein.
The Biochemical journal 1997;325 ( Pt 2)():391-400.
1997: L Burrows; S T Iobst; Kurt Drickamer
Selective binding of N-acetylglucosamine to the chicken hepatic lectin.
The Biochemical journal 1997;324 ( Pt 2)():673-80.
1997: Kurt Drickamer
Making a fitting choice: common aspects of sugar-binding sites in plant and animal lectins.
Structure (London, England : 1993) 1997;5(4):465-8.
1996: N I Ruiz; Kurt Drickamer
Differential ligand binding by two subunits of the rat liver asialoglycoprotein receptor.
Glycobiology 1996;6(5):551-9.
1996: O Blanck; S T Iobst; C Gabel; Kurt Drickamer
Introduction of selectin-like binding specificity into a homologous mannose-binding protein.
The Journal of biological chemistry 1996;271(13):7289-92.
1996: S T Iobst; Kurt Drickamer
Selective sugar binding to the carbohydrate recognition domains of the rat hepatic and macrophage asialoglycoprotein receptors.
The Journal of biological chemistry 1996;271(12):6686-93.
1996: Kurt Drickamer
Ca(2+)-dependent sugar recognition by animal lectins.
Biochemical Society transactions 1996;24(1):146-50.
1996: Kenneth K-S Ng; Kurt Drickamer; William I Weis
Structural analysis of monosaccharide recognition by rat liver mannose-binding protein.
The Journal of biological chemistry 1996;271(2):663-74.
1996: William I Weis; Kurt Drickamer
Structural basis of lectin-carbohydrate recognition.
Annual review of biochemistry 1996;65():441-73.
1994: William I Weis; Kurt Drickamer
Trimeric structure of a C-type mannose-binding protein.
Structure (London, England : 1993) 1994;2(12):1227-40.
1994: S T Iobst; Kurt Drickamer
Binding of sugar ligands to Ca(2+)-dependent animal lectins. II. Generation of high-affinity galactose binding by site-directed mutagenesis.
The Journal of biological chemistry 1994;269(22):15512-9.
1994: S T Iobst; M R Wormald; W I Weis; R A Dwek; Kurt Drickamer
Binding of sugar ligands to Ca(2+)-dependent animal lectins. I. Analysis of mannose binding by site-directed mutagenesis and NMR.
The Journal of biological chemistry 1994;269(22):15505-11.
1994: Kurt Drickamer
Three-dimensional view of a selectin cell adhesion molecule.
Glycobiology 1994;4(3):245-8.
1993: F Verrey; Kurt Drickamer
Determinants of oligomeric structure in the chicken liver glycoprotein receptor.
The Biochemical journal 1993;292 ( Pt 1)():149-55.
1993: Kurt Drickamer
Recognition of complex carbohydrates by Ca(2+)-dependent animal lectins.
Biochemical Society transactions 1993;21(2):456-9.
1993: S Saleque; N Ruiz; Kurt Drickamer
Expression and characterization of a carbohydrate-binding fragment of rat aggrecan.
Glycobiology 1993;3(2):185-90.
1993: M E Taylor; Kurt Drickamer
Structural requirements for high affinity binding of complex ligands by the macrophage mannose receptor.
The Journal of biological chemistry 1993;268(1):399-404.
1992: W I Weis; Kurt Drickamer; Wayne A Hendrickson
Structure of a C-type mannose-binding protein complexed with an oligosaccharide.
Nature 1992;360(6400):127-34.
1992: Kurt Drickamer
Engineering galactose-binding activity into a C-type mannose-binding protein.
Nature 1992;360(6400):183-6.
1992: S J Kim; N Ruiz; K Bezouska; Kurt Drickamer
Organization of the gene encoding the human macrophage mannose receptor (MRC1).
Genomics 1992;14(3):721-7.
1992: M E Taylor; Kurt Drickamer
Expression and purification of the cytoplasmic tail of an endocytic receptor by fusion to a carbohydrate-recognition domain.
Protein expression and purification 1992;3(4):308-12.
1992: M S Quesenberry; Kurt Drickamer
Role of conserved and nonconserved residues in the Ca(2+)-dependent carbohydrate-recognition domain of a rat mannose-binding protein. Analysis by random cassette mutagenesis.
The Journal of biological chemistry 1992;267(15):10831-41.
1992: Robert A Childs; J R Wright; G F Ross; CT Yuen; Alexander M Lawson; Wengang Chai; Kurt Drickamer; Ten Feizi
Specificity of lung surfactant protein SP-A for both the carbohydrate and the lipid moieties of certain neutral glycolipids.
The Journal of biological chemistry 1992;267(14):9972-9.
1992: M E Taylor; K Bezouska; Kurt Drickamer
Contribution to ligand binding by multiple carbohydrate-recognition domains in the macrophage mannose receptor.
The Journal of biological chemistry 1992;267(3):1719-26.
1992: W I Weis; M S Quesenberry; M E Taylor; K Bezouska; Wayne A Hendrickson; Kurt Drickamer
Molecular mechanisms of complex carbohydrate recognition at the cell surface.
Cold Spring Harbor symposia on quantitative biology 1992;57():281-9.
1991: Kurt Drickamer
Clearing up glycoprotein hormones.
Cell 1991;67(6):1029-32.
1991: W I Weis; R Kahn; Roger Fourme; Kurt Drickamer; Wayne A Hendrickson
Structure of the calcium-dependent lectin domain from a rat mannose-binding protein determined by MAD phasing.
Science (New York, N.Y.) 1991;254(5038):1608-15.
1991: M S Quesenberry; Kurt Drickamer
Determination of the minimum carbohydrate-recognition domain in two C-type animal lectins.
Glycobiology 1991;1(6):615-21.
1991: W I Weis; G V Crichlow; H M Murthy; Wayne A Hendrickson; Kurt Drickamer
Physical characterization and crystallization of the carbohydrate-recognition domain of a mannose-binding protein from rat.
The Journal of biological chemistry 1991;266(31):20678-86.
1991: K Bezouska; G V Crichlow; J M Rose; M E Taylor; Kurt Drickamer
Evolutionary conservation of intron position in a subfamily of genes encoding carbohydrate-recognition domains.
The Journal of biological chemistry 1991;266(18):11604-9.
1991: M E Taylor; Kurt Drickamer
Carbohydrate-recognition domains as tools for rapid purification of recombinant eukaryotic proteins.
The Biochemical journal 1991;274 ( Pt 2)():575-80.
1990: Robert A Childs; Ten Feizi; CT Yuen; Kurt Drickamer; M S Quesenberry
Differential recognition of core and terminal portions of oligosaccharide ligands by carbohydrate-recognition domains of two mannose-binding proteins.
The Journal of biological chemistry 1990;265(34):20770-7.
1990: M E Taylor; J T Conary; M R Lennartz; P D Stahl; Kurt Drickamer
Primary structure of the mannose receptor contains multiple motifs resembling carbohydrate-recognition domains.
The Journal of biological chemistry 1990;265(21):12156-62.
1990: F Verrey; Thierry Gilbert; T Mellow; G Proulx; Kurt Drickamer
Endocytosis via coated pits mediated by glycoprotein receptor in which the cytoplasmic tail is replaced by unrelated sequences.
Cell regulation 1990;1(6):471-86.
1989: Peter Parham; Frances M Brodsky; Kurt Drickamer
The occurrence of disulphide bonds in purified clathrin light chains.
The Biochemical journal 1989;257(3):775-81.
1989: Kurt Drickamer
Demonstration of carbohydrate-recognition activity in diverse proteins which share a common primary structure motif.
Biochemical Society transactions 1989;17(1):13-5.
1988: Jeffrey A Loeb; Kurt Drickamer
Conformational changes in the chicken receptor for endocytosis of glycoproteins. Modulation of ligand-binding activity by Ca2+ and pH.
The Journal of biological chemistry 1988;263(20):9752-60.
1988: Kurt Drickamer
Two distinct classes of carbohydrate-recognition domains in animal lectins.
The Journal of biological chemistry 1988;263(20):9557-60.
1988: D F Halberg; G Proulx; K Doege; Y Yamada; Kurt Drickamer
A segment of the cartilage proteoglycan core protein has lectin-like activity.
The Journal of biological chemistry 1988;263(19):9486-90.
1988: B L Hill; Kurt Drickamer; Frances M Brodsky; Peter Parham
Identification of the phosphorylation sites of clathrin light chain LCb.
The Journal of biological chemistry 1988;263(12):5499-501.
1988: T E Mellow; D Halberg; Kurt Drickamer
Endocytosis of N-acetylglucosamine-containing glycoproteins by rat fibroblasts expressing a single species of chicken liver glycoprotein receptor.
The Journal of biological chemistry 1988;263(11):5468-73.
1987: Kurt Drickamer
Membrane receptors that mediate glycoprotein endocytosis: structure and biosynthesis.
Kidney international. Supplement 1987;23():S167-83.
1987: D F Halberg; R E Wager; D C Farrell; J Hildreth; M S Quesenberry; Jeffrey A Loeb; Eric C Holland; Kurt Drickamer
Major and minor forms of the rat liver asialoglycoprotein receptor are independent galactose-binding proteins. Primary structure and glycosylation heterogeneity of minor receptor forms.
The Journal of biological chemistry 1987;262(20):9828-38.
1987: Jeffrey A Loeb; Kurt Drickamer
The chicken receptor for endocytosis of glycoproteins contains a cluster of N-acetylglucosamine-binding sites.
The Journal of biological chemistry 1987;262(7):3022-9.
1986: E C Hsueh; Eric C Holland; G M Carrera; Kurt Drickamer
The rat liver asialoglycoprotein receptor polypeptide must be inserted into a microsome to achieve its active conformation.
The Journal of biological chemistry 1986;261(11):4940-7.
1986: Eric C Holland; Kurt Drickamer
Signal recognition particle mediates the insertion of a transmembrane protein which has a cytoplasmic NH2 terminus.
The Journal of biological chemistry 1986;261(3):1286-92.
1985: J O Leung; Eric C Holland; Kurt Drickamer
Characterization of the gene encoding the major rat liver asialoglycoprotein receptor.
The Journal of biological chemistry 1985;260(23):12523-7.
1984: Eric C Holland; J O Leung; Kurt Drickamer
Rat liver asialoglycoprotein receptor lacks a cleavable NH2-terminal signal sequence.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(23):7338-42.
1984: Kurt Drickamer; J F Mamon; G Binns; J O Leung
Primary structure of the rat liver asialoglycoprotein receptor. Structural evidence for multiple polypeptide species.
The Journal of biological chemistry 1984;259(2):770-8.