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Robert Drillien

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Judit Osz; Arnaud Poterszman; Karine Pradeau-Aubreton; Robert Drillien; Isabelle Kolb-Cheynel; Dino Moras; Marc Ruff; Nathalie Troffer-Charlier; Natacha Rochel
Expression of functional full-length hSRC-1 in eukaryotic cells using modified vaccinia virus Ankara and baculovirus.
Brian C Jester; Marc Ruff; Robert Drillien; Catherine Florentz
Using Vaccinia's innate ability to introduce DNA into mammalian cells for production of recombinant proteins.
Julie Dimier; Audrey Ferrier-Rembert; Karine Pradeau-Aubreton; Matthias Hebben; Danièle Spehner; Anne-Laure Favier; Danielle Gratier; Daniel Garin; Jean-Marc Crance; Robert Drillien
Deletion of major nonessential genomic regions in the vaccinia virus Lister strain enhances attenuation without altering vaccine efficacy in mice.

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All Publications

2012: Judit Osz; Arnaud Poterszman; Karine Pradeau-Aubreton; Robert Drillien; Isabelle Kolb-Cheynel; Dino Moras; Marc Ruff; Nathalie Troffer-Charlier; Natacha Rochel
Expression of functional full-length hSRC-1 in eukaryotic cells using modified vaccinia virus Ankara and baculovirus.
Analytical biochemistry 2012;426(2):106-8.
2011: Brian C Jester; Marc Ruff; Robert Drillien; Catherine Florentz
Using Vaccinia's innate ability to introduce DNA into mammalian cells for production of recombinant proteins.
Journal of biotechnology 2011;156(3):211-3.
2011: Julie Dimier; Audrey Ferrier-Rembert; Karine Pradeau-Aubreton; Matthias Hebben; Danièle Spehner; Anne-Laure Favier; Danielle Gratier; Daniel Garin; Jean-Marc Crance; Robert Drillien
Deletion of major nonessential genomic regions in the vaccinia virus Lister strain enhances attenuation without altering vaccine efficacy in mice.
Journal of virology 2011;85(10):5016-26.
2010: Karine Pradeau-Aubreton; Marc Ruff; Jean-Marie Garnier; Patrick Schultz; Robert Drillien
Vectors for recombinational cloning and gene expression in mammalian cells using modified vaccinia virus Ankara.
Analytical biochemistry 2010;404(1):103-5.
2009: Aude Garcel; julien perino; Jean-Marc Crance; Robert Drillien; Daniel Garin; Anne-Laure Favier
Phenotypic and genetic diversity of the traditional Lister smallpox vaccine.
Vaccine 2009;27(5):708-17.
2008: Danièle Spehner; Robert Drillien
Extracellular vesicles containing virus-encoded membrane proteins are a byproduct of infection with modified vaccinia virus Ankara.
Virus research 2008;137(1):129-36.
2008: Audrey Ferrier-Rembert; Robert Drillien; Jean-Nicolas Tournier; Daniel Garin; Jean-Marc Crance
Short- and long-term immunogenicity and protection induced by non-replicating smallpox vaccine candidates in mice and comparison with the traditional 1st generation vaccine.
Vaccine 2008;26(14):1794-804.
2007: Matthias Hebben; Jan Brants; Catherine Birck; Jean-Pierre Samama; Bohdan Wasylyk; Danièle Spehner; Karine Pradeau; Arban Domi; Bernard Moss; Patrick Schultz; Robert Drillien
High level protein expression in mammalian cells using a safe viral vector: modified vaccinia virus Ankara.
Protein expression and purification 2007;56(2):269-78.
2007: Audrey Ferrier-Rembert; Robert Drillien; Bernard Meignier; Daniel Garin; Jean-Marc Crance
Safety, immunogenicity and protective efficacy in mice of a new cell-cultured Lister smallpox vaccine candidate.
Vaccine 2007;25(49):8290-7.
2007: Aude Garcel; Jean-Marc Crance; Robert Drillien; Daniel Garin; Anne-Laure Favier
Genomic sequence of a clonal isolate of the vaccinia virus Lister strain employed for smallpox vaccination in France and its comparison to other orthopoxviruses.
The Journal of general virology 2007;88(Pt 7):1906-16.
2007: Audrey Ferrier-Rembert; Robert Drillien; Jean-Nicolas Tournier; Daniel Garin; Jean-Marc Crance
Intranasal cowpox virus infection of the mouse as a model for preclinical evaluation of smallpox vaccines.
Vaccine 2007;25(25):4809-17.
2007: Audrey Ferrier-Rembert; Jean-Nicolas Tournier; Robert Drillien; Daniel Garin; Jean-Marc Crance
CD4+ T cells play a pivotal role in the control of cowpox virus infection in mice.
Viral immunology 2007;20(1):214-20.
2004: Jye-Chian Hsiao; Che-Sheng Chung; Robert Drillien; Wen Chang
The cowpox virus host range gene, CP77, affects phosphorylation of eIF2 alpha and vaccinia viral translation in apoptotic HeLa cells.
Virology 2004;329(1):199-212.
2004: Robert Drillien; Danièle Spehner; Daniel Hanau
Modified vaccinia virus Ankara induces moderate activation of human dendritic cells.
The Journal of general virology 2004;85(Pt 8):2167-75.
2004: Danièle Spehner; S De Carlo; Robert Drillien; Frank Weiland; K Mildner; Daniel Hanau; Hanns-Joachim Rziha
Appearance of the bona fide spiral tubule of ORF virus is dependent on an intact 10-kilodalton viral protein.
Journal of virology 2004;78(15):8085-93.
2004: Robert Drillien; D Spehner; D Garin
[Viruses considered for a third generation anti-smallpox vaccine].
Médecine et maladies infectieuses 2004;34 Suppl 1():S51-4.
2004: Daniel Garin; Jean-Marc Crance; Florence Fuchs; B Autran; Robert Drillien
[Update on smallpox vaccines].
Médecine et maladies infectieuses 2004;34(1):20-7.
2003: NATALE SCARAMOZZINO; Guenhaël Sanz; Jean-Marc Crance; Murat Saparbaev; Robert Drillien; Jacques Laval; Bodil Kavli; Daniel Garin
Characterisation of the substrate specificity of homogeneous vaccinia virus uracil-DNA glycosylase.
Nucleic acids research 2003;31(16):4950-7.
2002: Danièle Spehner; Robert Drillien; Fabienne Proamer; Daniel Hanau; L Edelmann
Embedding in Spurr's resin is a good choice for immunolabelling after freeze drying as shown with chemically unfixed dendritic cells.
Journal of microscopy 2002;207(Pt 1):1-4.
2002: Dan Lipsker; Umit Ziylan; Danièle Spehner; Fabienne Proamer; Huguette Bausinger; Pascale Jeannin; Jean Salamero; Alain Bohbot; Jean-Pierre Cazenave; Robert Drillien; Yves Delneste; Daniel Hanau; Henri de la Salle
Heat shock proteins 70 and 60 share common receptors which are expressed on human monocyte-derived but not epidermal dendritic cells.
European journal of immunology 2002;32(2):322-32.
2000: Danièle Spehner; Robert Drillien; Fabienne Proamer; C Houssais-Pêcheur; M A Zanta; Michel Geist; Karine Dott; Jean-Marc Balloul
Enveloped virus is the major virus form produced during productive infection with the modified vaccinia virus Ankara strain.
Virology 2000;273(1):9-15.
2000: Dan Lipsker; Danièle Spehner; Robert Drillien; P Schmitt; B Cribier; E Heid; R L Humbel; E Grosshans
Schnitzler syndrome: heterogeneous immunopathological findings involving IgM-skin interactions.
The British journal of dermatology 2000;142(5):954-9.
2000: Robert Drillien; Danièle Spehner; Alain Bohbot; Daniel Hanau
Vaccinia virus-related events and phenotypic changes after infection of dendritic cells derived from human monocytes.
Virology 2000;268(2):471-81.
1999: S Vincent; Danièle Spehner; Serge Manié; R Delorme; Robert Drillien; Denis Gerlier
Inefficient measles virus budding in murine L.CD46 fibroblasts.
Virology 1999;265(2):185-95.
1999: Peter M Howley; B Lafont; Danièle Spehner; K Kaelin; Martin A Billeter; Robert Drillien
A functional measles virus replication and transcription machinery encoded by the vaccinia virus genome.
Journal of virological methods 1999;79(1):65-74.
1998: T Cathomen; B Mrkic; Danièle Spehner; Robert Drillien; R Naef; Jovan Pavlovic; Adriano Aguzzi; Martin A Billeter; Roberto Cattaneo
A matrix-less measles virus is infectious and elicits extensive cell fusion: consequences for propagation in the brain.
The EMBO journal 1998;17(14):3899-908.
1997: Danièle Spehner; Robert Drillien; Peter M Howley
The assembly of the measles virus nucleoprotein into nucleocapsid-like particles is modulated by the phosphoprotein.
Virology 1997;232(2):260-8.
1996: P M Howley; Danièle Spehner; Robert Drillien
A vaccinia virus transfer vector using a GUS reporter gene inserted into the I4L locus.
Gene 1996;172(2):233-7.
1995: P Zajac; Danièle Spehner; Robert Drillien
The vaccinia virus J5L open reading frame encodes a polypeptide expressed late during infection and required for viral multiplication.
Virus research 1995;37(2):163-73.
1994: Jean-Marc Balloul; R B Acres; M Geist; K Dott; L Stefani; Daniel Schmitt; Robert Drillien; Danièle Spehner; I McKenzie; P X Xing
Recombinant MUC 1 vaccinia virus: a potential vector for immunotherapy of breast cancer.
Cellular and molecular biology (Noisy-le-Grand, France) 1994;40 Suppl 1():49-59.
1993: C J Buchholz; Danièle Spehner; Robert Drillien; Wolfgang J Neubert; H E Homann
The conserved N-terminal region of Sendai virus nucleocapsid protein NP is required for nucleocapsid assembly.
Journal of virology 1993;67(10):5803-12.
1993: W Chen; Robert Drillien; Danièle Spehner; R Mark L Buller
In vitro and in vivo study of the ectromelia virus homolog of the vaccinia virus K1L host range gene.
Virology 1993;196(2):682-93.
1993: Nancy Oguiura; Danièle Spehner; Robert Drillien
Detection of a protein encoded by the vaccinia virus C7L open reading frame and study of its effect on virus multiplication in different cell lines.
The Journal of general virology 1993;74 ( Pt 7)():1409-13.
1993: T Fabian Wild; A Bernard; Danièle Spehner; D Villeval; Robert Drillien
Vaccination of mice against canine distemper virus-induced encephalitis with vaccinia virus recombinants encoding measles or canine distemper virus antigens.
Vaccine 1993;11(4):438-44.
1992: W Chen; Robert Drillien; Danièle Spehner; R Mark L Buller
Restricted replication of ectromelia virus in cell culture correlates with mutations in virus-encoded host range gene.
Virology 1992;187(2):433-42.
1992: T Fabian Wild; A Bernard; Danièle Spehner; Robert Drillien
Construction of vaccinia virus recombinants expressing several measles virus proteins and analysis of their efficacy in vaccination of mice.
The Journal of general virology 1992;73 ( Pt 2)():359-67.
1991: Danièle Spehner; A Kirn; Robert Drillien
Assembly of nucleocapsidlike structures in animal cells infected with a vaccinia virus recombinant encoding the measles virus nucleoprotein.
Journal of virology 1991;65(11):6296-300.
1990: F Wild; Pascale Giraudon; Danièle Spehner; Robert Drillien; J P Lecocq
Fowlpox virus recombinant encoding the measles virus fusion protein: protection of mice against fatal measles encephalitis.
Vaccine 1990;8(5):441-2.
1990: Danièle Spehner; Robert Drillien; J P Lecocq
Construction of fowlpox virus vectors with intergenic insertions: expression of the beta-galactosidase gene and the measles virus fusion gene.
Journal of virology 1990;64(2):527-33.
1989: S Gillard; Danièle Spehner; Robert Drillien; A Kirn
Antibodies directed against a synthetic peptide enable detection of a protein encoded by a vaccinia virus host range gene that is conserved within the Orthopoxvirus genus.
Journal of virology 1989;63(4):1814-7.
1988: Danièle Spehner; S Gillard; Robert Drillien; A Kirn
A cowpox virus gene required for multiplication in Chinese hamster ovary cells.
Journal of virology 1988;62(4):1297-304.
1988: Robert Drillien; Danièle Spehner; A Kirn; Pascale Giraudon; Robin Buckland; F Wild; J P Lecocq
Protection of mice from fatal measles encephalitis by vaccination with vaccinia virus recombinants encoding either the hemagglutinin or the fusion protein.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(4):1252-6.
1987: Robert Drillien; Danièle Spehner; D Villeval; J P Lecocq
Similar genetic organization between a region of fowlpox virus DNA and the vaccinia virus HindIII J fragment despite divergent location of the thymidine kinase gene.
Virology 1987;160(1):203-9.
1986: S Gillard; Danièle Spehner; Robert Drillien; A Kirn
Localization and sequence of a vaccinia virus gene required for multiplication in human cells.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(15):5573-7.
1985: H de la Salle; W Altenburger; R Elkaim; K Dott; A Dieterlé; Robert Drillien; J P Cazenave; P Tolstoshev; J P Lecocq
Active gamma-carboxylated human factor IX expressed using recombinant DNA techniques.
Nature 1985;316(6025):268-70.
1985: S Gillard; Danièle Spehner; Robert Drillien
Mapping of a vaccinia host range sequence by insertion into the viral thymidine kinase gene.
Journal of virology 1985;53(1):316-8.
1984: M P Kieny; Richard Lathe; Robert Drillien; Danièle Spehner; S Skory; D Schmitt; T Wiktor; H Koprowski; J P Lecocq
Expression of rabies virus glycoprotein from a recombinant vaccinia virus.
Nature 1984;312(5990):163-6.
1983: Robert Drillien; Danièle Spehner
Physical mapping of vaccinia virus temperature-sensitive mutations.
Virology 1983;131(2):385-93.
1982: Robert Drillien; Danièle Spehner; A Kirn
Complementation and genetic linkage between vaccinia virus temperature-sensitive mutants.
Virology 1982;119(2):372-81.