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Wulf Dröge
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22
Schmitz, Lienhard
18
Kinscherf, Ralf
17
Hehner, Steffen
16
Breitkreutz, Raoul
15
Hack, Volker
15
Hofmann, Thomas
14
Schulze-Osthoff, Klaus
10
Hildebrandt, Wulf
9
Holm, Eggert
9
Lehmann, Volker
7
Krammer, Peter
6
Möller, Andreas
6
Ratter, F
6
Bärtsch, Peter
5
Babylon, A
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All Publications
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2007: Holm Eggert; Hildebrandt Wulf; Kinscherf Ralf; Dröge Wulf
Low postabsorptive net protein degradation in male cancer patients: lack of sensitivity to regulatory amino acids?
Oncology reports 2007;17(3):695-700.
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2007: Bonaterra Gabriel A; Hildebrandt Wulf; Bodens Anne; Sauer Roland; Dugi Klaus A; Deigner Hans-Peter; Turcanu Dan; Heinle Helmut; Dröge Wulf; Metz Jürgen; Kinscherf Ralf
Increased gene expression of scavenger receptors and proinflammatory markers in peripheral blood mononuclear cells of hyperlipidemic males.
Journal of molecular medicine (Berlin, Germany) 2007;85(2):181-90.
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2006: Sido Bernd; Seel Cornelia; Hochlehnert Achim; Breitkreutz Raoul; Dröge Wulf
Low intestinal glutamine level and low glutaminase activity in Crohn's disease: a rational for glutamine supplementation?
Digestive diseases and sciences 2006;51(12):2170-9.
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2006: Dröge Wulf; Kinscherf Ralf; Hildebrandt Wulf; Schmitt Thomas
The deficit in low molecular weight thiols as a target for antiageing therapy.
Current drug targets 2006;7(11):1505-12.
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2006: Schmitt Thomas L; Klein Helmut; Dröge Wulf
Hydrogen peroxide inhibits activity of the IGF-1 receptor kinase.
Redox report : communications in free radical research 2006;11(3):105-9.
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2005: Dröge Wulf
Oxidative stress and ageing: is ageing a cysteine deficiency syndrome?
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2005;360(1464):2355-72.
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2005: Dröge Wulf
Oxidative enhancement of insulin receptor signaling: experimental findings and clinical implications.
Antioxidants & redox signaling 2005;7(7-8):1071-7.
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2005: Schmitt Thomas L; Hotz-Wagenblatt Agnes; Klein Helmut; Dröge Wulf
Interdependent regulation of insulin receptor kinase activity by ADP and hydrogen peroxide.
The Journal of biological chemistry 2005;280(5):3795-801.
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2005: Bonaterra Gabriel A; Hildebrandt Wulf; Bodens Anne; Sauer Roland; Dugi Klaus A; Deigner Hans-Peter; Dröge Wulf; Metz Jürgen; Kinscherf Ralf
Increased cyclooxygenase-2 expression in peripheral blood mononuclear cells of smokers and hyperlipidemic subjects.
Free radical biology & medicine 2005;38(2):235-42.
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2004: Hildebrandt Wulf; Hamann Andreas; Krakowski-Roosen Holger; Kinscherf Ralf; Dugi Klaus; Sauer Roland; Lacher Sabrina; Nöbel Nuria; Bodens Anne; Bellou Vassiliki; Edler Lutz; Nawroth Peter; Dröge Wulf
Effect of thiol antioxidant on body fat and insulin reactivity.
Journal of molecular medicine (Berlin, Germany) 2004;82(5):336-44.
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2004: Dröge Wulf
Autophagy and aging--importance of amino acid levels.
Mechanisms of ageing and development 2004;125(3):161-8.
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2003: Möller Andreas; Sirma Hüseyin; Hofmann Thomas G; Staege Hannah; Gresko Ekaterina; Lüdi Katharina Schmid; Klimczak Elisabeth; Dröge Wulf; Will Hans; Schmitz M Lienhard
Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression.
Oncogene 2003;22(54):8731-7.
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2003: Kinscherf Ralf; Cafaltzis Konstantinos; Röder Falk; Hildebrandt Wulf; Edler Lutz; Deigner Hans Peter; Breitkreutz Raoul; Feussner Giso; Kreuzer Jörg; Werle Egon; Michel Gerd; Metz Jürgen; Dröge Wulf
Cholesterol levels linked to abnormal plasma thiol concentrations and thiol/disulfide redox status in hyperlipidemic subjects.
Free radical biology & medicine 2003;35(10):1286-92.
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2003: Möller Andreas; Sirma Hüseyin; Hofmann Thomas G; Rueffer Sven; Klimczak Elisabeth; Dröge Wulf; Will Hans; Schmitz M Lienhard
PML is required for homeodomain-interacting protein kinase 2 (HIPK2)-mediated p53 phosphorylation and cell cycle arrest but is dispensable for the formation of HIPK domains.
Cancer research 2003;63(15):4310-4.
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2003: Hauer Klaus; Hildebrandt Wulf; Sehl Yvonne; Edler Lutz; Oster Peter; Dröge Wulf
Improvement in muscular performance and decrease in tumor necrosis factor level in old age after antioxidant treatment.
Journal of molecular medicine (Berlin, Germany) 2003;81(2):118-25.
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2003: Dienz Oliver; Möller Andreas; Strecker Andreas; Stephan Nadja; Krammer Peter H; Dröge Wulf; Schmitz M Lienhard
Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and phospholipase C gamma 1 are required for NF-kappa B activation and lipid raft recruitment of protein kinase C theta induced by T cell costimulation.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(1):365-72.
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2003: Hildebrandt Wulf; Dröge Wulf
Thiol-mediated redox regulation.
Forum of nutrition 2003;56():199-200.
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2003: Dröge Wulf
Oxidative stress and aging.
Advances in experimental medicine and biology 2003;543():191-200.
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2002: Dröge Wulf
Aging-related changes in the thiol/disulfide redox state: implications for the use of thiol antioxidants.
Experimental gerontology 2002;37(12):1333-45.
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2002: Hildebrandt W; Kinscherf R; Hauer K; Holm E; Dröge W
Plasma cystine concentration and redox state in aging and physical exercise.
Mechanisms of ageing and development 2002;123(9):1269-81.
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2002: Dröge Wulf
The plasma redox state and ageing.
Ageing research reviews 2002;1(2):257-78.
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2002: Hildebrandt Wulf; Alexander Steve; Bärtsch Peter; Dröge Wulf
Effect of N-acetyl-cysteine on the hypoxic ventilatory response and erythropoietin production: linkage between plasma thiol redox state and O(2) chemosensitivity.
Blood 2002;99(5):1552-5.
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2002: Dröge Wulf
Free radicals in the physiological control of cell function.
Physiological reviews 2002;82(1):47-95.
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2002: Hofmann Thomas G; Möller Andreas; Sirma Hüaeyin; Zentgraf Hanswalter; Taya Yoichi; Dröge Wulf; Will Hans; Schmitz M Lienhard
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2.
Nature cell biology 2002;4(1):1-10.
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2002: Schmitz M Lienhard; Bacher Susanne; Dröge Wulf
Molecular analysis of mitogen-activated protein kinase signaling pathways induced by reactive oxygen intermediates.
Methods in enzymology 2002;352():53-61.
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2002: Hotz-Wagenblatt Agnes; Dröge Wulf
Redox-mediated functional and structural changes in insulin receptor kinase.
Methods in enzymology 2002;348():288-96.
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2001: Breitkreutz R; Wagner J; Tokus M; Benner A; Rossol S; Pittack N; Stein J; Dröge W; Holm E
Flux of amino acids and energy substrates across the leg in weight-stable HIV-infected patients with acute opportunistic infections: indication of a slow protein wasting process.
Journal of molecular medicine (Berlin, Germany) 2001;79(11):671-8.
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2001: Taut F J; Breitkreutz R; Zapletal C M; Thies J C; Babylon A; Martin E; Dröge W
Influence of N-acetylcysteine on hepatic amino acid metabolism in patients undergoing orthotopic liver transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 2001;14(5):329-33.
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2001: Hofmann T G; Möller A; Hehner S P; Welsch D; Dröge W; Schmitz M L
CD95-induced JNK activation signals are transmitted by the death-inducing signaling complex (DISC), but not by Daxx.
International journal of cancer. Journal international du cancer 2001;93(2):185-91.
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2001: Möller A; Dienz O; Hehner S P; Dröge W; Schmitz M L
Protein kinase C theta cooperates with Vav1 to induce JNK activity in T-cells.
The Journal of biological chemistry 2001;276(23):20022-8.
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2001: Bacher S; Grosshans J; Dröge W; Schmitz M L
The Drosophila proteins Pelle and Tube induce JNK/AP-1 activity in mammalian cells.
FEBS letters 2001;497(2-3):153-8.
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2000: Hofmann T G; Mincheva A; Lichter P; Dröge W; Schmitz M L
Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34.
Biochimie 2000;82(12):1123-7.
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2000: Dröge W; Breitkreutz R
Glutathione and immune function.
The Proceedings of the Nutrition Society 2000;59(4):595-600.
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2000: Hehner S P; Breitkreutz R; Shubinsky G; Unsoeld H; Schulze-Osthoff K; Schmitz M L; Dröge W
Enhancement of T cell receptor signaling by a mild oxidative shift in the intracellular thiol pool.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(8):4319-28.
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2000: Umansky V; Rocha M; Breitkreutz R; Hehner S; Bucur M; Erbe N; Dröge W; Ushmorov A
Glutathione is a factor of resistance of Jurkat leukemia cells to nitric oxide-mediated apoptosis.
Journal of cellular biochemistry 2000;78(4):578-87.
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2000: Kaltschmidt B; Kaltschmidt C; Hofmann T G; Hehner S P; Dröge W; Schmitz M L
The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulus.
European journal of biochemistry / FEBS 2000;267(12):3828-35.
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2000: Hehner S P; Li-Weber M; Giaisi M; Dröge W; Krammer P H; Schmitz M L
Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(7):3829-36.
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2000: Hehner S P; Hofmann T G; Ushmorov A; Dienz O; Wing-Lan Leung I; Lassam N; Scheidereit C; Dröge W; Schmitz M L
Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex.
Molecular and cellular biology 2000;20(7):2556-68.
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2000: Hofmann T G; Hehner S P; Dröge W; Schmitz M L
Caspase-dependent cleavage and inactivation of the Vav1 proto-oncogene product during apoptosis prevents IL-2 transcription.
Oncogene 2000;19(9):1153-63.
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2000: Breitkreutz R; Holm S; Pittack N; Beichert M; Babylon A; Yodoi J; Dröge W
Massive loss of sulfur in HIV infection.
AIDS research and human retroviruses 2000;16(3):203-9.
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2000: Breitkreutz R; Babylon A; Hack V; Schuster K; Tokus M; Böhles H; Hagmüller E; Edler L; Holm E; Dröge W
Effect of carnitine on muscular glutamate uptake and intramuscular glutathione in malignant diseases.
British journal of cancer 2000;82(2):399-403.
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2000: Breitkreutz R; Pittack N; Nebe C T; Schuster D; Brust J; Beichert M; Hack V; Daniel V; Edler L; Dröge W
Improvement of immune functions in HIV infection by sulfur supplementation: two randomized trials.
Journal of molecular medicine (Berlin, Germany) 2000;78(1):55-62.
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1999: Dröge W; Breitkreutz R
N-acetyl-cysteine in the therapy of HIV-positive patients.
Current opinion in clinical nutrition and metabolic care 1999;2(6):493-8.
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1999: Hehner S P; Hofmann T G; Dröge W; Schmitz M L
The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(10):5617-23.
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1999: Hehner S P; Hofmann T G; Dröge W; Schmitz M L
Inhibition of tyrosine phosphatases induces apoptosis independent from the CD95 system.
Cell death and differentiation 1999;6(9):833-41.
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1999: Schmid E; Hotz-Wagenblatt A; Hacj V; Dröge W
Phosphorylation of the insulin receptor kinase by phosphocreatine in combination with hydrogen peroxide: the structural basis of redox priming.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(12):1491-500.
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1999: Hehner S P; Hofmann T G; Ratter F; Dröge W; Schmitz M L
Inhibition of tyrosine phosphatases antagonizes CD95-mediated apoptosis.
European journal of biochemistry / FEBS 1999;264(1):132-9.
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1999: Ushmorov A; Hack V; Dröge W
Differential reconstitution of mitochondrial respiratory chain activity and plasma redox state by cysteine and ornithine in a model of cancer cachexia.
Cancer research 1999;59(14):3527-34.
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1999: Dröge W
Cysteine and glutathione in catabolic conditions and immunological dysfunction.
Current opinion in clinical nutrition and metabolic care 1999;2(3):227-33.
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1999: Kaltschmidt B; Kaltschmidt C; Hehner S P; Dröge W; Schmitz M L
Repression of NF-kappaB impairs HeLa cell proliferation by functional interference with cell cycle checkpoint regulators.
Oncogene 1999;18(21):3213-25.
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1999: Ushmorov A; Ratter F; Lehmann V; Dröge W; Schirrmacher V; Umansky V
Nitric-oxide-induced apoptosis in human leukemic lines requires mitochondrial lipid degradation and cytochrome C release.
Blood 1999;93(7):2342-52.
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1999: Taut F J; Zapletal C M; Klar E; Motsch J; Thies J C; Babylon A; Martin E; Dröge W; Breitkreutz R
Sulfur-containing metabolites of N-acetylcysteine in patients undergoing orthotopic liver transplantation.
Transplantation proceedings 1999;31(1-2):411-3.
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1999: Dumont A; Hehner S P; Hofmann T G; Ueffing M; Dröge W; Schmitz M L
Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB.
Oncogene 1999;18(3):747-57.
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1999: Schmid E; Hotz-Wagenblatt A; Dröge W
Inhibition of the insulin receptor kinase phosphorylation by nitric oxide: functional and structural aspects.
Antioxidants & redox signaling 1999;1(1):45-53.
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1998: Hofmann T G; Hehner S P; Bacher S; Dröge W; Schmitz M L
Various glucocorticoids differ in their ability to induce gene expression, apoptosis and to repress NF-kappaB-dependent transcription.
FEBS letters 1998;441(3):441-6.
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1998: Umansky V; Hehner S P; Dumont A; Hofmann T G; Schirrmacher V; Dröge W; Schmitz M L
Co-stimulatory effect of nitric oxide on endothelial NF-kappaB implies a physiological self-amplifying mechanism.
European journal of immunology 1998;28(8):2276-82.
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1998: Hehner S P; Hofmann T G; Ratter F; Dumont A; Dröge W; Schmitz M L
Tumor necrosis factor-alpha-induced cell killing and activation of transcription factor NF-kappaB are uncoupled in L929 cells.
The Journal of biological chemistry 1998;273(29):18117-21.
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1998: Schmid E; El Benna J; Galter D; Klein G; Dröge W
Redox priming of the insulin receptor beta-chain associated with altered tyrosine kinase activity and insulin responsiveness in the absence of tyrosine autophosphorylation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(10):863-70.
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1998: Hack V; Breitkreutz R; Kinscherf R; Röhrer H; Bärtsch P; Taut F; Benner A; Dröge W
The redox state as a correlate of senescence and wasting and as a target for therapeutic intervention.
Blood 1998;92(1):59-67.
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1998: Sido B; Hack V; Hochlehnert A; Lipps H; Herfarth C; Dröge W
Impairment of intestinal glutathione synthesis in patients with inflammatory bowel disease.
Gut 1998;42(4):485-92.
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1998: Hehner S P; Heinrich M; Bork P M; Vogt M; Ratter F; Lehmann V; Schulze-Osthoff K; Dröge W; Schmitz M L
Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta.
The Journal of biological chemistry 1998;273(3):1288-97.
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1998: Dröge W; Hack V; Breitkreutz R; Holm E; Shubinsky G; Schmid E; Galter D
Role of cysteine and glutathione in signal transduction, immunopathology and cachexia.
BioFactors (Oxford, England) 1998;8(1-2):97-102.
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1997: Dröge W; Holm E
Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997;11(13):1077-89.
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1997: Hack V; Gross A; Böhme A; Stahl-Hennig C; Dröge W
Decrease in phosphocreatine level in skeletal muscle of SIV-infected rhesus macaques correlates with decrease in intracellular glutathione.
AIDS research and human retroviruses 1997;13(13):1089-91.
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1997: Holm E; Hack V; Tokus M; Breitkreutz R; Babylon A; Dröge W
Linkage between postabsorptive amino acid release and glutamate uptake in skeletal muscle tissue of healthy young subjects, cancer patients, and the elderly.
Journal of molecular medicine (Berlin, Germany) 1997;75(6):454-61.
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1997: Hack V; Weiss C; Friedmann B; Suttner S; Schykowski M; Erbe N; Benner A; Bärtsch P; Dröge W
Decreased plasma glutamine level and CD4+ T cell number in response to 8 wk of anaerobic training.
The American journal of physiology 1997;272(5 Pt 1):E788-95.
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1997: Hack V; Schmid D; Breitkreutz R; Stahl-Henning C; Drings P; Kinscherf R; Taut F; Holm E; Dröge W
Cystine levels, cystine flux, and protein catabolism in cancer cachexia, HIV/SIV infection, and senescence.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997;11(1):84-92.
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1997: Dröge W; Gross A; Hack V; Kinscherf R; Schykowski M; Bockstette M; Mihm S; Galter D
Role of cysteine and glutathione in HIV infection and cancer cachexia: therapeutic intervention with N-acetylcysteine.
Advances in pharmacology (San Diego, Calif.) 1997;38():581-600.
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1996: Gross A; Hack V; Stahl-Hennig C; Dröge W
Elevated hepatic gamma-glutamylcysteine synthetase activity and abnormal sulfate levels in liver and muscle tissue may explain abnormal cysteine and glutathione levels in SIV-infected rhesus macaques.
AIDS research and human retroviruses 1996;12(17):1639-41.
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1996: Shatrov V A; Ratter F; Gruber A; Dröge W; Lehmann V
HIV type 1 glycoprotein 120 amplifies tumor necrosis factor-induced NF-kappa B activation in Jurkat cells.
AIDS research and human retroviruses 1996;12(13):1209-16.
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1996: Hack V; Gross A; Kinscherf R; Bockstette M; Fiers W; Berke G; Dröge W
Abnormal glutathione and sulfate levels after interleukin 6 treatment and in tumor-induced cachexia.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(10):1219-26.
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1996: Kinscherf R; Hack V; Fischbach T; Friedmann B; Weiss C; Edler L; Bärtsch P; Dröge W
Low plasma glutamine in combination with high glutamate levels indicate risk for loss of body cell mass in healthy individuals: the effect of N-acetyl-cysteine.
Journal of molecular medicine (Berlin, Germany) 1996;74(7):393-400.
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1996: Ratter F; Germer M; Fischbach T; Schulze-Osthoff K; Peter M E; Dröge W; Krammer P H; Lehmann V
S-adenosylhomocysteine as a physiological modulator of Apo-1-mediated apoptosis.
International immunology 1996;8(7):1139-47.
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1996: Hack V; Stütz O; Kinscherf R; Schykowski M; Kellerer M; Holm E; Dröge W
Elevated venous glutamate levels in (pre)catabolic conditions result at least partly from a decreased glutamate transport activity.
Journal of molecular medicine (Berlin, Germany) 1996;74(6):337-43.
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1996: Schenk H; Vogt M; Dröge W; Schulze-Osthoff K
Thioredoxin as a potent costimulus of cytokine expression.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(2):765-71.
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1995: Los M; Schenk H; Hexel K; Baeuerle P A; Dröge W; Schulze-Osthoff K
IL-2 gene expression and NF-kappa B activation through CD28 requires reactive oxygen production by 5-lipoxygenase.
The EMBO journal 1995;14(15):3731-40.
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1995: Los M; Van de Craen M; Penning L C; Schenk H; Westendorp M; Baeuerle P A; Dröge W; Krammer P H; Fiers W; Schulze-Osthoff K
Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis.
Nature 1995;375(6526):81-3.
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1995: Westendorp M O; Shatrov V A; Schulze-Osthoff K; Frank R; Kraft M; Los M; Krammer P H; Dröge W; Lehmann V
HIV-1 Tat potentiates TNF-induced NF-kappa B activation and cytotoxicity by altering the cellular redox state.
The EMBO journal 1995;14(3):546-54.
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1995: Mihm S; Galter D; Dröge W
Modulation of transcription factor NF kappa B activity by intracellular glutathione levels and by variations of the extracellular cysteine supply.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(2):246-52.
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1995: Weiss C; Kinscherf R; Roth S; Friedmann B; Fischbach T; Reus J; Dröge W; Bärtsch P
Lymphocyte subpopulations and concentrations of soluble CD8 and CD4 antigen after anaerobic training.
International journal of sports medicine 1995;16(2):117-21.
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1995: Los M; Dröge W; Stricker K; Baeuerle P A; Schulze-Osthoff K
Hydrogen peroxide as a potent activator of T lymphocyte functions.
European journal of immunology 1995;25(1):159-65.
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1995: Dröge W; Kinscherf R; Mihm S; Galter D; Roth S; Gmünder H; Fischbach T; Bockstette M
Thiols and the immune system: effect of N-acetylcysteine on T cell system in human subjects.
Methods in enzymology 1995;251():255-70.
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1995: Schulze-Osthoff K; Schenk H; Dröge W
Effects of thioredoxin on activation of transcription factor NF-kappa B.
Methods in enzymology 1995;252():253-64.
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1994: Dröge W; Schulze-Osthoff K; Mihm S; Galter D; Schenk H; Eck H P; Roth S; Gmünder H
Functions of glutathione and glutathione disulfide in immunology and immunopathology.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1994;8(14):1131-8.
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1994: Schulze-Osthoff K; Walczak H; Dröge W; Krammer P H
Cell nucleus and DNA fragmentation are not required for apoptosis.
The Journal of cell biology 1994;127(1):15-20.
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1994: Schulze-Osthoff K; Krammer P H; Dröge W
Divergent signalling via APO-1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death.
The EMBO journal 1994;13(19):4587-96.
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1994: Los M; Dröge W; Schulze-Osthoff K
Inhibition of activation of transcription factor AP-1 by CD28 signalling in human T-cells.
The Biochemical journal 1994;302 ( Pt 1)():119-23.
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1994: Galter D; Mihm S; Dröge W
Distinct effects of glutathione disulphide on the nuclear transcription factor kappa B and the activator protein-1.
European journal of biochemistry / FEBS 1994;221(2):639-48.
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1994: Roth S; Dröge W
Glutathione reverses the inhibition of T cell responses by superoptimal numbers of "nonprofessional" antigen presenting cells.
Cellular immunology 1994;155(1):183-94.
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1994: Kinscherf R; Fischbach T; Mihm S; Roth S; Hohenhaus-Sievert E; Weiss C; Edler L; Bärtsch P; Dröge W
Effect of glutathione depletion and oral N-acetyl-cysteine treatment on CD4+ and CD8+ cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1994;8(6):448-51.
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1994: Schenk H; Klein M; Erdbrügger W; Dröge W; Schulze-Osthoff K
Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-kappa B and AP-1.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(5):1672-6.
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1994: Dröge W; Eck H P; Mihm S; Roth S; Kinscherf R; Fischbach T
The role of a cysteine and glutathione deficiency in the immunopathology of HIV infection.
Acta microbiologica et immunologica Hungarica 1994;41 Suppl():17-20.
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1994: Dröge W; Eck H P; Mihm S
Oxidant-antioxidant status in human immunodeficiency virus infection.
Methods in enzymology 1994;233():594-601.
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1994: Dröge W; Mihm S; Bockstette M; Roth S
Effect of reactive oxygen intermediates and antioxidants on proliferation and function of T lymphocytes.
Methods in enzymology 1994;234():135-51.
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1993: Dröge W; Murthy K K; Stahl-Hennig C; Hartung S; Plesker R; Rouse S; Peterhans E; Kinscherf R; Fischbach T; Eck H P
Plasma amino acid dysregulation after lentiviral infection.
AIDS research and human retroviruses 1993;9(9):807-9.
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1992: Dröge W; Eck H P; Mihm S
HIV-induced cysteine deficiency and T-cell dysfunction--a rationale for treatment with N-acetylcysteine.
Immunology today 1992;13(6):211-4.
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1992: Lim J S; Eck H P; Gmünder H; Dröge W
Expression of increased immunogenicity by thiol-releasing tumor variants.
Cellular immunology 1992;140(2):345-56.
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1991: Dröge W; Eck H P; Gmünder H; Mihm S
Requirement for prooxidant and antioxidant states in T cell mediated immune responses.--Relevance for the pathogenetic mechanisms of AIDS?
Klinische Wochenschrift 1991;69(21-23):1118-22.
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1991: Gmünder H; Dröge W
Differential effects of glutathione depletion on T cell subsets.
Cellular immunology 1991;138(1):229-37.
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1991: Gmünder H; Eck H P; Dröge W
Low membrane transport activity for cystine in resting and mitogenically stimulated human lymphocyte preparations and human T cell clones.
European journal of biochemistry / FEBS 1991;201(1):113-7.
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1991: Dröge W; Eck H P; Gmünder H; Mihm S
Modulation of lymphocyte functions and immune responses by cysteine and cysteine derivatives.
The American journal of medicine 1991;91(3C):140S-144S.
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1991: Roth S; Gmünder H; Dröge W
Regulation of intracellular glutathione levels and lymphocyte functions by lactate.
Cellular immunology 1991;136(1):95-104.
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1991: Lehmann V; Benninghoff B; Dröge W
Selective induction of metabolic activation programs in peritoneal macrophages by lipopolysaccharide substructures.
Infection and immunity 1991;59(8):2822-7.
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1991: Roth S; Dröge W
Regulation of interleukin 2 production, interleukin 2 mRNA expression and intracellular glutathione levels in ex vivo derived T lymphocytes by lactate.
European journal of immunology 1991;21(8):1933-7.
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1991: Eck H P; Stahl-Hennig C; Hunsmann G; Dröge W
Metabolic disorder as early consequence of simian immunodeficiency virus infection in rhesus macaques.
Lancet 1991;338(8763):346-7.
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1991: Benninghoff B; Lehmann V; Eck H P; Dröge W
Production of citrulline and ornithine by interferon-gamma treated macrophages.
International immunology 1991;3(5):413-7.
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1991: Mihm S; Ennen J; Pessara U; Kurth R; Dröge W
Inhibition of HIV-1 replication and NF-kappa B activity by cysteine and cysteine derivatives.
AIDS (London, England) 1991;5(5):497-503.
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1991: Dröge W; Wolf M; Häcker-Shahin B; Kriegbaum H; Benninghoff B; Gmünder H; Eck H P; Mihm S
Immunomodulatory action of eicosanoids and other small molecular weight products of macrophages.
Annali dell'Istituto superiore di sanità 1991;27(1):67-9.
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1990: Gmünder H; Roth S; Eck H P; Gallas H; Mihm S; Dröge W
Interleukin-2 mRNA expression, lymphokine production and DNA synthesis in glutathione-depleted T cells.
Cellular immunology 1990;130(2):520-8.
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1990: Gmünder H; Eck H P; Benninghoff B; Roth S; Dröge W
Macrophages regulate intracellular glutathione levels of lymphocytes. Evidence for an immunoregulatory role of cysteine.
Cellular immunology 1990;129(1):32-46.
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1990: Eck H P; Betzler M; Schlag P; Dröge W
Partial recovery of lymphocyte activity in patients with colorectal carcinoma after curative surgical treatment and return of plasma glutamate concentrations to normal levels.
Journal of cancer research and clinical oncology 1990;116(6):648-50.
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1989: Eck H P; Gmünder H; Hartmann M; Petzoldt D; Daniel V; Dröge W
Low concentrations of acid-soluble thiol (cysteine) in the blood plasma of HIV-1-infected patients.
Biological chemistry Hoppe-Seyler 1989;370(2):101-8.
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1989: Eck H P; Dröge W
Influence of the extracellular glutamate concentration on the intracellular cyst(e)ine concentration in macrophages and on the capacity to release cysteine.
Biological chemistry Hoppe-Seyler 1989;370(2):109-13.
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1989: Benninghoff B; Dröge W; Lehmann V
The lipopolysaccharide-induced stimulation of peritoneal macrophages involves at least two signal pathways. Partial stimulation by lipid A precursors.
European journal of biochemistry / FEBS 1989;179(3):589-94.
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1989: Mihm S; Risso A; Stöhr M; Oberdorfer F; Dröge W
Downregulation of T cell growth factor production by ornithine decarboxylase and its product putrescine: D,L-alpha-difluoromethylornithine suppresses general protein synthesis but augments simultaneously the production of interleukin-2.
Experimental cell research 1989;180(2):383-98.
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1989: Eck H P; Frey H; Dröge W
Elevated plasma glutamate concentrations in HIV-1-infected patients may contribute to loss of macrophage and lymphocyte functions.
International immunology 1989;1(4):367-72.
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1989: Eck H P; Drings P; Dröge W
Plasma glutamate levels, lymphocyte reactivity and death rate in patients with bronchial carcinoma.
Journal of cancer research and clinical oncology 1989;115(6):571-4.
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1988: Dröge W; Eck H P; Näher H; Pekar U; Daniel V
Abnormal amino-acid concentrations in the blood of patients with acquired immunodeficiency syndrome (AIDS) may contribute to the immunological defect.
Biological chemistry Hoppe-Seyler 1988;369(3):143-8.
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1988: Dröge W; Wehrmaker A; Eck H P
Alanine inhibits cytotoxic responses: its production by different tumor cell lines explains differences in their immunogenicity.
Cancer detection and prevention 1988;11(3-6):151-6.
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1988: Dröge W; Eck H P; Betzler M; Schlag P; Drings P; Ebert W
Plasma glutamate concentration and lymphocyte activity.
Journal of cancer research and clinical oncology 1988;114(2):124-8.
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1987: Dröge W; Eck H P; Betzler M; Näher H
Elevated plasma glutamate levels in colorectal carcinoma patients and in patients with acquired immunodeficiency syndrome (AIDS).
Immunobiology 1987;174(4-5):473-9.
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1987: Kriegbaum H; Benninghoff B; Häcker-Shahin B; Dröge W
Correlation of immunogenicity and production of ornithine by peritoneal macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(3):899-904.
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1987: Dröge W; Benninghoff B; Lehmann V
Tumor necrosis factor augments the immunogenicity and the production of L-ornithine by peritoneal macrophages.
Lymphokine research 1987;6(2):111-7.
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1986: Wehrmaker A; Lehmann V; Dröge W
Analysis of protective and cytotoxic immune responses in vivo against metabolically inactivated and untreated cells of a mutagenized tumor line (requirements for tumor immunogenicity).
Cellular immunology 1986;101(2):290-8.
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1986: Dröge W; Eck H P; Kriegbaum H; Mihm S
Release of L-alanine by tumor cells.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(4):1383-6.
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1984: Moyers C; Pottmeyer-Gerber C; Gerber M; Buszello H; Dröge W
Mitomycin C-treated or irradiated concanavalin A-activated T cells augment the activation of cytotoxic T cells in vivo.
Cellular immunology 1984;88(1):123-8.
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1984: Dröge W; Moyers C; Wehrmaker A; Schmidt H; Panknin S; Männel D; Falk W
Capacity of different cell types to stimulate cytotoxic T lymphocyte precursor cells in the presence of interleukin 2.
Journal of immunology (Baltimore, Md. : 1950) 1984;132(6):2749-59.
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