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Nathalie Droin

Research Profile

Chemicals & Drugs

Living Beings

Disorders

Chronic Myelomonocytic Leukemia

Physiology

Anatomy

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Publications

TOP 3
Nathalie M Droin; Leslie Guéry; Naïma Benikhlef; Eric Solary
Targeting apoptosis proteins in hematological malignancies.
Raphaël Itzykson; Olivier Kosmider; Guillaume Meurice; Margot Morabito; Cédric Oréar; Uwe Platzbecker; Claude Preudhomme; Philippe Rameau; Aline Renneville; Lionel Adès; Olivier A Bernard; Céline Berthon; François Delhommeau; Nathalie M Droin; Pierre Fenaux; Michaëla Fontenay; Olivier Gagey; William Vainchenker; Eric Solary
Clonal architecture of chronic myelomonocytic leukemias.
Iléana Antony-Debré; Véronique Baccini; Dominique Bluteau; Françoise Boehlen; Yunhua Chang; Caroline Deswarte; Nathalie M Droin; Remi Favier; Raphael Itzykson; Guy Leverger; Margot Morabito; Aline Renneville; Eric Solary; William Vainchenker; Hana Raslova
MYH10 protein expression in platelets as a biomarker of RUNX1 and FLI1 alterations.

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All Publications

2013: Nathalie M Droin; Leslie Guéry; Naïma Benikhlef; Eric Solary
Targeting apoptosis proteins in hematological malignancies.
Cancer letters 2013;332(2):325-34.
2013: Raphaël Itzykson; Olivier Kosmider; Guillaume Meurice; Margot Morabito; Cédric Oréar; Uwe Platzbecker; Claude Preudhomme; Philippe Rameau; Aline Renneville; Lionel Adès; Olivier A Bernard; Céline Berthon; François Delhommeau; Nathalie M Droin; Pierre Fenaux; Michaëla Fontenay; Olivier Gagey; William Vainchenker; Eric Solary
Clonal architecture of chronic myelomonocytic leukemias.
Blood 2013;121(12):2186-98.
2012: Iléana Antony-Debré; Véronique Baccini; Dominique Bluteau; Françoise Boehlen; Yunhua Chang; Caroline Deswarte; Nathalie M Droin; Remi Favier; Raphael Itzykson; Guy Leverger; Margot Morabito; Aline Renneville; Eric Solary; William Vainchenker; Hana Raslova
MYH10 protein expression in platelets as a biomarker of RUNX1 and FLI1 alterations.
Blood 2012;120(13):2719-22.
2012: Jean-Noël Bastie; Nathalie M Droin; Eric Solary; Romain Aucagne; Laurent Delva
Heterogeneity of molecular markers in chronic myelomonocytic leukemia: a disease associated with several gene alterations.
Cellular and molecular life sciences : CMLS 2012;69(17):2853-61.
2011: Leslie Guery; Arnaud Jacquel; Gaetan Jego; Bénédicte Manoury; Catherine Paul; Naïma Benikhlef; Radj Cally; Nathalie M Droin; Erick Dufour; Thomas Gautier; Tom Vanden Berghe; Peter Vandenabeele; Eric Solary
Fine-tuning nucleophosmin in macrophage differentiation and activation.
Blood 2011;118(17):4694-704.
2011: Thorsten Braun; Benoit de Renzis; François Dreyfus; Nathalie M Droin; Pierre Fenaux; Michaëla Fontenay; Claude Gardin; Raphael Itzykson; Bertrand Joly; Ingrid Lafon; Kamel Laribi; Guillaume Meurice; Cédric Oréar; Claude Preudhomme; Christian Recher; Aline Renneville; Bruno Royer; Laurence Sanhes; Eric Solary; Andrea Toma; Anne Vekhoff; Norbert Vey; Lionel Ades; Krimo Bouabdallah
Molecular predictors of response to decitabine in advanced chronic myelomonocytic leukemia: a phase 2 trial.
Blood 2011;118(14):3824-31.
2011: Romain Aucagne; Jean-Noël Bastie; Nathalie M Droin; Eric Solary; Laurent Delva
[TIF1γ: a tumor suppressor gene in chronic myelomonocytic leukemia].
Médecine sciences : M/S 2011;27(8-9):696-8.
2011: Romain Aucagne; Nathalie M Droin; Jérôme Paggetti; Brice Lagrange; Anne Largeot; Arlette Hammann; Amandine Bataille; Laurent Martin; Kai-Ping Yan; Pierre Fenaux; Régine Losson; Eric Solary; Jean-Noël Bastie; Laurent Delva
Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia.
The Journal of clinical investigation 2011;121(6):2361-70.
2010: Nathalie M Droin; Arnaud Jacquel; Jean-Baptiste Hendra; Cindy Racoeur; Caroline Truntzer; Delphine Pecqueur; Naïma Benikhlef; Marion Ciudad; Leslie Guery; Valérie Jooste; Erick Dufour; Pierre Fenaux; Bruno Quesnel; Olivier Kosmider; Michaëla Fontenay; Patrick Ducoroy; Eric Solary
Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia.
Blood 2010;115(1):78-88.
2009: Arnaud Jacquel; Naïma Benikhlef; Jérôme Paggetti; Najoua LALAOUI; Leslie Guery; Erick K Dufour; Marion Ciudad; Cindy Racoeur; Olivier Micheau; Laurent Delva; Nathalie M Droin; Eric Solary
Colony-stimulating factor-1-induced oscillations in phosphatidylinositol-3 kinase/AKT are required for caspase activation in monocytes undergoing differentiation into macrophages.
Blood 2009;114(17):3633-41.
2008: Nathalie M Droin; Séverine Cathelin; Arnaud Jacquel; Leslie Guéry; Carmen Garrido; Michaëla Fontenay; Olivier Hermine; Eric Solary
A role for caspases in the differentiation of erythroid cells and macrophages.
Biochimie 2008;90(2):416-22.
2008: Carl De Trez; Kirsten Schneider; Karen G Potter; Nathalie M Droin; James Fulton; Paula S Norris; Suk-won Ha; Yang-Xin Fu; Theresa Murphy; Kenneth M Murphy; Klaus Pfeffer; Chris A Benedict; Carl Ware
The inhibitory HVEM-BTLA pathway counter regulates lymphotoxin receptor signaling to achieve homeostasis of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):238-48.
2007: Juscilene S Menezes; Peter van den Elzen; Jordan Thornes; Donald Huffman; Nathalie M Droin; Emanual Maverakis; Eli E Sercarz
A public T cell clonotype within a heterogeneous autoreactive repertoire is dominant in driving EAE.
The Journal of clinical investigation 2007;117(8):2176-85.
2007: Beatrice Bailly-Maitre; Emilie A Bard-Chapeau; Frederic Luciano; Nathalie M Droin; Jean-Marie Bruey; Benjamin Faustin; Christina L Kress; Juan M Zapata; John C Reed
Mice lacking bi-1 gene show accelerated liver regeneration.
Cancer research 2007;67(4):1442-50.
2006: Emilie A Bard-Chapeau; Jing Yuan; Nathalie M Droin; Shinong Long; Eric Erquan Zhang; Thanh V Nguyen; Gen-Sheng Feng
Concerted functions of Gab1 and Shp2 in liver regeneration and hepatoprotection.
Molecular and cellular biology 2006;26(12):4664-74.
2006: Maya Saleh; John C Mathison; Melissa K Wolinski; Steve J Bensinger; Patrick Fitzgerald; Nathalie M Droin; Richard J Ulevitch; Douglas R Green; Donald W Nicholson
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice.
Nature 2006;440(7087):1064-8.
2006: Beatrice Bailly-Maitre; Constantino Fondevila; Fady Kaldas; Nathalie M Droin; Frederic Luciano; Jean-Ehrland Ricci; Rhonda Croxton; Maryla Krajewska; Juan M Zapata; Jerzy W Kupiec-Weglinski; Douglas Farmer; John C Reed
Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2809-14.
2005: Deborah J Kasprowicz; Nathalie M Droin; David M Soper; Fred Ramsdell; Douglas R Green; Steven F Ziegler
Dynamic regulation of FoxP3 expression controls the balance between CD4+ T cell activation and cell death.
European journal of immunology 2005;35(12):3424-32.
2005: Rina Barouch-Bentov; Edward E Lemmens; Junru Hu; edith janssen; Nathalie M Droin; Jim (Jianxun) Song; Stephen P Schoenberger; Amnon Altman
Protein kinase C-theta is an early survival factor required for differentiation of effector CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(8):5126-34.
2005: edith janssen; Nathalie M Droin; Edward E Lemmens; Michael J Pinkoski; Steven J Bensinger; Benjamin D Ehst; Thomas Griffith; Douglas R Green; Stephen P Schoenberger
CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.
Nature 2005;434(7029):88-93.
2005: N Parent; Alain Théophile Sané; Nathalie M Droin; Richard Bertrand
Procaspase-2S inhibits procaspase-3 processing and activation, preventing ROCK-1-mediated apoptotic blebbing and body formation in human B lymphoma Namalwa cells.
Apoptosis : an international journal on programmed cell death 2005;10(2):313-22.
2004: Amnon Altman; Sandra Kaminski; Valere Busuttil; Nathalie M Droin; Junru Hu; Yuri Tadevosyan; Robert A Hipskind; Martin Villalba
Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway.
European journal of immunology 2004;34(7):2001-11.
2004: Elise Schmitt; Arnaud Parcellier; François Ghiringhelli; Noelia Casares; Sandeep Gurbuxani; Nathalie M Droin; Ahmed Hamai; Marie O Pequignot; Arlette Hammann; Monique Moutet; Annie Fromentin; Guido Kroemer; Eric Solary; Carmen Garrido
Increased immunogenicity of colon cancer cells by selective depletion of cytochrome C.
Cancer research 2004;64(8):2705-11.
2004: Nathalie M Droin; Douglas R Green
Role of Bcl-2 family members in immunity and disease.
Biochimica et biophysica acta 2004;1644(2-3):179-88.
2004: Jerry E Chipuk; Tomomi Kuwana; Lisa Bouchier-Hayes; Nathalie M Droin; Donald D Newmeyer; Martin Schuler; Douglas R Green
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis.
Science (New York, N.Y.) 2004;303(5660):1010-4.
2003: Eric R James; Lorie Robertson; Erich Ehlert; Patrick Fitzgerald; Nathalie M Droin; Douglas R Green
Presence of a transcriptionally active glucocorticoid receptor alpha in lens epithelial cells.
Investigative ophthalmology & visual science 2003;44(12):5269-76.
2003: Nathalie M Droin; Michael J Pinkoski; Emmanuel Dejardin; Douglas R Green
Egr family members regulate nonlymphoid expression of Fas ligand, TRAIL, and tumor necrosis factor during immune responses.
Molecular and cellular biology 2003;23(21):7638-47.
2003: Douglas R Green; Nathalie M Droin; Michael Pinkoski
Activation-induced cell death in T cells.
Immunological reviews 2003;193():70-81.
2003: Marianne J B van Stipdonk; Gijs Hardenberg; Martijn Bijker; Edward E Lemmens; Nathalie M Droin; Douglas R Green; Stephen P Schoenberger
Dynamic programming of CD8+ T lymphocyte responses.
Nature immunology 2003;4(4):361-5.
2002: Michael J Pinkoski; Nathalie M Droin; Tesu Lin; Laurent Genestier; Thomas A Ferguson; Douglas R Green
Nonlymphoid Fas ligand in peptide-induced peripheral lymphocyte deletion.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(25):16174-9.
2002: Michael J Pinkoski; Nathalie M Droin; Douglas R Green
Tumor necrosis factor alpha up-regulates non-lymphoid Fas-ligand following superantigen-induced peripheral lymphocyte activation.
The Journal of biological chemistry 2002;277(44):42380-5.
2002: Emmanuel Dejardin; Nathalie M Droin; Mireille Delhase; Elvira Haas; Yixue Cao; Constantin Makris; Zhi-Wei Li; Michael Karin; Carl Ware; Douglas R Green
The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways.
Immunity 2002;17(4):525-35.
2002: Christine Bonzon; Nathalie M Droin; U Maurer; Jean-Ehrland Ricci
Death in paradise.
Cell death and differentiation 2002;9(7):780-2.
2002: Katja C Zimmermann; Jean-Ehrland Ricci; Nathalie M Droin; Douglas R Green
The role of ARK in stress-induced apoptosis in Drosophila cells.
The Journal of cell biology 2002;156(6):1077-87.
2001: Eric Solary; Stéphanie Plenchette; Olivier Sordet; Cédric Rébé; P Ducoroy; Rodolphe Filomenko; Jean-Marie Bruey; Nathalie M Droin; Laurent Corcos
Modulation of apoptotic pathways triggered by cytotoxic agents.
Thérapie 2001;56(5):511-8.
2001: Nathalie M Droin; F Bichat; Cédric Rébé; Anne Wotawa; Olivier Sordet; Arlette Hammann; Richard Bertrand; Eric Solary
Involvement of caspase-2 long isoform in Fas-mediated cell death of human leukemic cells.
Blood 2001;97(6):1835-44.
2001: Nathalie M Droin; Cédric Rébé; F Bichat; Arlette Hammann; Richard Bertrand; Eric Solary
Modulation of apoptosis by procaspase-2 short isoform: selective inhibition of chromatin condensation, apoptotic body formation and phosphatidylserine externalization.
Oncogene 2001;20(2):260-9.
2000: Nathalie M Droin; Myriam Beauchemin; Eric Solary; Richard Bertrand
Identification of a caspase-2 isoform that behaves as an endogenous inhibitor of the caspase cascade.
Cancer research 2000;60(24):7039-47.
2000: Eric Solary; Nathalie M Droin; Ali Bettaieb; Laurent Corcos; Marie-Thérèse Dimanche-Boitrel; Carmen Garrido
Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies.
Leukemia 2000;14(10):1833-49.
1999: Béatrice Eymin; Olivier Sordet; Nathalie M Droin; B Munsch; M Haugg; M Van de Craen; P Vandenabeele; Eric Solary
Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity.
Oncogene 1999;18(34):4839-47.
1999: N Favre; Bernard Bonnotte; Nathalie M Droin; Annie Fromentin; Eric Solary; François Martin
FAS(CD95) ligand expression by tumor cell variants can be unrelated to their capacity to induce tolerance or immune rejection.
International journal of cancer. Journal international du cancer 1999;82(3):359-67.
1999: Olivier Sordet; Ali Bettaieb; Jean-Marie Bruey; Béatrice Eymin; Nathalie M Droin; M Ivarsson; Carmen Garrido; Eric Solary
Selective inhibition of apoptosis by TPA-induced differentiation of U937 leukemic cells.
Cell death and differentiation 1999;6(4):351-61.
1999: Béatrice Eymin; M Haugg; Nathalie M Droin; Olivier Sordet; Marie-Thérèse Dimanche-Boitrel; Eric Solary
p27Kip1 induces drug resistance by preventing apoptosis upstream of cytochrome c release and procaspase-3 activation in leukemic cells.
Oncogene 1999;18(7):1411-8.
1998: Nathalie M Droin; L Dubrez; Béatrice Eymin; C Renvoizé; Jacqueline Bréard; Marie-Thérèse Dimanche-Boitrel; Eric Solary
Upregulation of CASP genes in human tumor cells undergoing etoposide-induced apoptosis.
Oncogene 1998;16(22):2885-94.
1998: Bernard Bonnotte; N Favre; S Reveneau; Olivier Micheau; Nathalie M Droin; Carmen Garrido; A Fontana; Bruno Chauffert; Eric Solary; François Martin
Cancer cell sensitization to fas-mediated apoptosis by sodium butyrate.
Cell death and differentiation 1998;5(6):480-7.
1998: L Dubrez; Béatrice Eymin; Olivier Sordet; Nathalie M Droin; Ali G Turhan; Eric Solary
BCR-ABL delays apoptosis upstream of procaspase-3 activation.
Blood 1998;91(7):2415-22.
1998: Eric Solary; Béatrice Eymin; Nathalie M Droin; M Haugg
Proteases, proteolysis, and apoptosis.
Cell biology and toxicology 1998;14(2):121-32.