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Guy Droogmans

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Karel Talavera; Keiko Yasumatsu; Thomas Voets; Guy Droogmans; Noriatsu Shigemura; Yuzo Ninomiya; Robert Margolskee; Bernd Nilius
Heat activation of TRPM5 underlies thermal sensitivity of sweet taste.
Bernd Nilius; Karel Talavera; Grzegorz Owsianik; Jean Prenen; Guy Droogmans; Thomas Voets
Gating of TRP channels: a voltage connection?
Nina D Ullrich; Thomas Voets; Jean Prenen; Rudi Vennekens; Karel Talavera; Guy Droogmans; Bernd Nilius
Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice.

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2005: Karel Talavera; Keiko Yasumatsu; Thomas Voets; Guy Droogmans; Noriatsu Shigemura; Yuzo Ninomiya; Robert Margolskee; Bernd Nilius
Heat activation of TRPM5 underlies thermal sensitivity of sweet taste.
Nature 2005;438(7070):1022-5.
2005: Bernd Nilius; Karel Talavera; Grzegorz Owsianik; Jean Prenen; Guy Droogmans; Thomas Voets
Gating of TRP channels: a voltage connection?
The Journal of physiology 2005;567(Pt 1):35-44.
2005: Nina D Ullrich; Thomas Voets; Jean Prenen; Rudi Vennekens; Karel Talavera; Guy Droogmans; Bernd Nilius
Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice.
Cell calcium 2005;37(3):267-78.
2004: Joris Vriens; Grzegorz Owsianik; Thomas Voets; Guy Droogmans; Bernd Nilius
Invertebrate TRP proteins as functional models for mammalian channels.
Pflügers Archiv : European journal of physiology 2004;449(3):213-26.
2004: Bernd Nilius; Jean Prenen; Annelies Janssens; Thomas Voets; Guy Droogmans
Decavanadate modulates gating of TRPM4 cation channels.
The Journal of physiology 2004;560(Pt 3):753-65.
2004: Karel Talavera; Mik Staes; Annelies Janssens; Guy Droogmans; Bernd Nilius
Mechanism of arachidonic acid modulation of the T-type Ca2+ channel alpha1G.
The Journal of general physiology 2004;124(3):225-38.
2004: Thomas Voets; Guy Droogmans; Ulrich Wissenbach; Annelies Janssens; Veit Flockerzi; Bernd Nilius
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels.
Nature 2004;430(7001):748-54.
2004: Thomas Voets; Annelies Janssens; Guy Droogmans; Bernd Nilius
Outer pore architecture of a Ca2+-selective TRP channel.
The Journal of biological chemistry 2004;279(15):15223-30.
2004: Bernd Nilius; Jean Prenen; Thomas Voets; Guy Droogmans
Intracellular nucleotides and polyamines inhibit the Ca2+-activated cation channel TRPM4b.
Pflügers Archiv : European journal of physiology 2004;448(1):70-5.
2004: Bernd Nilius; Joris Vriens; Jean Prenen; Guy Droogmans; Thomas Voets
TRPV4 calcium entry channel: a paradigm for gating diversity.
American journal of physiology. Cell physiology 2004;286(2):C195-205.
2004: Joris Vriens; Hiroyuki Watanabe; Annelies Janssens; Guy Droogmans; Thomas Voets; Bernd Nilius
Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):396-401.
2004: Thomas Voets; Bernd Nilius; Susan Hoefs; Annemiete W C M van der Kemp; Guy Droogmans; René J M Bindels; Joost G J Hoenderop
TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption.
The Journal of biological chemistry 2004;279(1):19-25.
2003: Bernd Nilius; Jean Prenen; Guy Droogmans; Thomas Voets; Rudi Vennekens; Marc Freichel; Ulrich Wissenbach; Veit Flockerzi
Voltage dependence of the Ca2+-activated cation channel TRPM4.
The Journal of biological chemistry 2003;278(33):30813-20.
2003: Hiroyuki Watanabe; Joris Vriens; Jean Prenen; Guy Droogmans; Thomas Voets; Bernd Nilius
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels.
Nature 2003;424(6947):434-8.
2003: Karel Talavera; Annelies Janssens; Norbert Klugbauer; Guy Droogmans; Bernd Nilius
Extracellular Ca2+ modulates the effects of protons on gating and conduction properties of the T-type Ca2+ channel alpha1G (CaV3.1).
The Journal of general physiology 2003;121(6):511-28.
2003: Karel Talavera; Annelies Janssens; Norbert Klugbauer; Guy Droogmans; Bernd Nilius
Pore structure influences gating properties of the T-type Ca2+ channel alpha1G.
The Journal of general physiology 2003;121(6):529-40.
2003: Hiroyuki Watanabe; Joris Vriens; Annelies Janssens; Robert Wondergem; Guy Droogmans; Bernd Nilius
Modulation of TRPV4 gating by intra- and extracellular Ca2+.
Cell calcium 2003;33(5-6):489-95.
2003: Thomas Voets; Annelies Janssens; Jean Prenen; Guy Droogmans; Bernd Nilius
Mg2+-dependent gating and strong inward rectification of the cation channel TRPV6.
The Journal of general physiology 2003;121(3):245-60.
2003: Bernd Nilius; Freek A Weidema; Jean Prenen; Joost G J Hoenderop; Rudi Vennekens; Susan Hoefs; Guy Droogmans; René J M Bindels
The carboxyl terminus of the epithelial Ca(2+) channel ECaC1 is involved in Ca(2+)-dependent inactivation.
Pflügers Archiv : European journal of physiology 2003;445(5):584-8.
2003: Bernd Nilius; Guy Droogmans; Robert Wondergem
Transient receptor potential channels in endothelium: solving the calcium entry puzzle?
Endothelium : journal of endothelial cell research 2003;10(1):5-15.
2002: Hiroyuki Watanabe; Joris Vriens; Suk H Suh; Christopher D Benham; Guy Droogmans; Bernd Nilius
Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells.
The Journal of biological chemistry 2002;277(49):47044-51.
2002: Thomas Voets; Jean Prenen; Joris Vriens; Hiroyuki Watanabe; Annelies Janssens; Ulrich Wissenbach; Matthias Bödding; Guy Droogmans; Bernd Nilius
Molecular determinants of permeation through the cation channel TRPV4.
The Journal of biological chemistry 2002;277(37):33704-10.
2002: Bernd Nilius; Jean Prenen; Joost G J Hoenderop; Rudi Vennekens; Susan Hoefs; A Freek Weidema; Guy Droogmans; René J M Bindels
Fast and slow inactivation kinetics of the Ca2+ channels ECaC1 and ECaC2 (TRPV5 and TRPV6). Role of the intracellular loop located between transmembrane segments 2 and 3.
The Journal of biological chemistry 2002;277(34):30852-8.
2002: Chantal Maertens; Guy Droogmans; Rene Verbesselt; Bernd Nilius
Block of volume-regulated anion channels by selective serotonin reuptake inhibitors.
Naunyn-Schmiedeberg's archives of pharmacology 2002;366(2):158-65.
2002: Iris Carton; Dominique Trouet; Diane Hermans; Holger Barth; Klaus Aktories; Guy Droogmans; Nanna K Jorgensen; Else Hoffmann; Bernd Nilius; Jan Eggermont
RhoA exerts a permissive effect on volume-regulated anion channels in vascular endothelial cells.
American journal of physiology. Cell physiology 2002;283(1):C115-25.
2002: Suk H Suh; Hiroyuki Watanabe; Guy Droogmans; Bernd Nilius
ATP and nitric oxide modulate a Ca(2+)-activated non-selective cation current in macrovascular endothelial cells.
Pflügers Archiv : European journal of physiology 2002;444(3):438-45.
2002: Rudi Vennekens; Thomas Voets; René J M Bindels; Guy Droogmans; Bernd Nilius
Current understanding of mammalian TRP homologues.
Cell calcium 2002;31(6):253-64.
2002: Hiroyuki Watanabe; John B Davis; Darren Smart; Jeffrey C Jerman; Graham D Smith; Phil Hayes; Joris Vriens; William Cairns; Ulrich Wissenbach; Jean Prenen; Veit Flockerzi; Guy Droogmans; Christopher D Benham; Bernd Nilius
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives.
The Journal of biological chemistry 2002;277(16):13569-77.
2001: Thomas Voets; Jean Prenen; Andrea Fleig; Rudi Vennekens; Hiroyuki Watanabe; Joost G J Hoenderop; René J M Bindels; Guy Droogmans; Reinhold Penner; Bernd Nilius
CaT1 and the calcium release-activated calcium channel manifest distinct pore properties.
The Journal of biological chemistry 2001;276(51):47767-70.
2001: Joost G J Hoenderop; Rudi Vennekens; Dominik Müller; Jean Prenen; Guy Droogmans; René J M Bindels; Bernd Nilius
Function and expression of the epithelial Ca(2+) channel family: comparison of mammalian ECaC1 and 2.
The Journal of physiology 2001;537(Pt 3):747-61.
2001: Karel Talavera; Mik Staes; Annelies Janssens; Norbert Klugbauer; Guy Droogmans; Franz Hofmann; Bernd Nilius
Aspartate residues of the Glu-Glu-Asp-Asp (EEDD) pore locus control selectivity and permeation of the T-type Ca(2+) channel alpha(1G).
The Journal of biological chemistry 2001;276(49):45628-35.
2001: Bernd Nilius; Jean Prenen; Ulrich Wissenbach; Matthias Bödding; Guy Droogmans
Differential activation of the volume-sensitive cation channel TRP12 (OTRPC4) and volume-regulated anion currents in HEK-293 cells.
Pflügers Archiv : European journal of physiology 2001;443(2):227-33.
2001: Bernd Nilius; Jean Prenen; Rudi Vennekens; Joost G J Hoenderop; René J M Bindels; Guy Droogmans
Pharmacological modulation of monovalent cation currents through the epithelial Ca2+ channel ECaC1.
British journal of pharmacology 2001;134(3):453-62.
2001: Rudi Vennekens; Guy Droogmans; Bernd Nilius
Functional properties of the epithelial Ca2+ channel, ECaC.
General physiology and biophysics 2001;20(3):239-53.
2001: Dominique Trouet; Iris Carton; Diane Hermans; Guy Droogmans; Bernd Nilius; Jan Eggermont
Inhibition of VRAC by c-Src tyrosine kinase targeted to caveolae is mediated by the Src homology domains.
American journal of physiology. Cell physiology 2001;281(1):C248-56.
2001: Dominique Trouet; Diane Hermans; Guy Droogmans; Bernd Nilius; Jan Eggermont
Inhibition of volume-regulated anion channels by dominant-negative caveolin-1.
Biochemical and biophysical research communications 2001;284(2):461-5.
2001: Bernd Nilius; Jean Prenen; Rudi Vennekens; Joost G J Hoenderop; René J M Bindels; Guy Droogmans
Modulation of the epithelial calcium channel, ECaC, by intracellular Ca2+.
Cell calcium 2001;29(6):417-28.
2001: L Wei; Anne Vankeerberghen; Harry Cuppens; Jean-Jacques Cassiman; Guy Droogmans; Bernd Nilius
The C-terminal part of the R-domain, but not the PDZ binding motif, of CFTR is involved in interaction with Ca(2+)-activated Cl- channels.
Pflügers Archiv : European journal of physiology 2001;442(2):280-5.
2001: J Papassotiriou; Jan Eggermont; Guy Droogmans; Bernd Nilius
Ca(2+)-activated Cl- channels in Ehrlich ascites tumor cells are distinct from mCLCA1, 2 and 3.
Pflügers Archiv : European journal of physiology 2001;442(2):273-9.
2001: Rudi Vennekens; Jean Prenen; Joost G J Hoenderop; René J M Bindels; Guy Droogmans; Bernd Nilius
Modulation of the epithelial Ca2+ channel ECaC by extracellular pH.
Pflügers Archiv : European journal of physiology 2001;442(2):237-42.
2001: Marc Freichel; S H Suh; A Pfeifer; U Schweig; Claudia Trost; Petra Weissgerber; M Biel; Stephan E Philipp; Doris Freise; Guy Droogmans; Franz Hofmann; Veit Flockerzi; Bernd Nilius
Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice.
Nature cell biology 2001;3(2):121-7.
2001: Rudi Vennekens; Jean Prenen; Joost G J Hoenderop; René J M Bindels; Guy Droogmans; Bernd Nilius
Pore properties and ionic block of the rabbit epithelial calcium channel expressed in HEK 293 cells.
The Journal of physiology 2001;530(Pt 2):183-91.
2001: Bernd Nilius; Rudi Vennekens; Jean Prenen; Joost G J Hoenderop; Guy Droogmans; René J M Bindels
The single pore residue Asp542 determines Ca2+ permeation and Mg2+ block of the epithelial Ca2+ channel.
The Journal of biological chemistry 2001;276(2):1020-5.
2001: L Wei; Marc Freichel; Martine Jaspers; Harry Cuppens; Jean-Jacques Cassiman; Guy Droogmans; Veit Flockerzi; Bernd Nilius
Functional interaction between TRP4 and CFTR in mouse aorta endothelial cells.
BMC physiology 2001;1():3.
2001: Chantal Maertens; Guy Droogmans; P Chakraborty; Bernd Nilius
Inhibition of volume-regulated anion channels in cultured endothelial cells by the anti-oestrogens clomiphene and nafoxidine.
British journal of pharmacology 2001;132(1):135-42.
2001: Mik Staes; Karel Talavera; Norbert Klugbauer; Jean Prenen; Lubica Lacinova; Guy Droogmans; Franz Hofmann; Bernd Nilius
The amino side of the C-terminus determines fast inactivation of the T-type calcium channel alpha1G.
The Journal of physiology 2001;530(Pt 1):35-45.
2000: Meng-Ru Shen; Guy Droogmans; Jan Eggermont; Thomas Voets; J Clive Ellory; Bernd Nilius
Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells.
The Journal of physiology 2000;529 Pt 2():385-94.
2000: Chantal Maertens; L Wei; Guy Droogmans; Bernd Nilius
Inhibition of volume-regulated and calcium-activated chloride channels by the antimalarial mefloquine.
The Journal of pharmacology and experimental therapeutics 2000;295(1):29-36.
2000: Bernd Nilius; Rudi Vennekens; Jean Prenen; Joost G J Hoenderop; René J M Bindels; Guy Droogmans
Whole-cell and single channel monovalent cation currents through the novel rabbit epithelial Ca2+ channel ECaC.
The Journal of physiology 2000;527 Pt 2():239-48.
2000: R Z Sabirov; Jean Prenen; Guy Droogmans; Bernd Nilius
Extra- and intracellular proton-binding sites of volume-regulated anion channels.
The Journal of membrane biology 2000;177(1):13-22.
2000: Rudi Vennekens; Joost G J Hoenderop; Jean Prenen; M Stuiver; P H Willems; Guy Droogmans; Bernd Nilius; René J M Bindels
Permeation and gating properties of the novel epithelial Ca(2+) channel.
The Journal of biological chemistry 2000;275(6):3963-9.
2000: VG Manolopoulos; S Liekens; PIETER KOOLWIJK; Thomas Voets; E Peters; Guy Droogmans; Peter Lelkes; E De Clercq; Bernd Nilius
Inhibition of angiogenesis by blockers of volume-regulated anion channels.
General pharmacology 2000;34(2):107-16.
2000: Chantal Maertens; L Wei; Jan Tytgat; Guy Droogmans; Bernd Nilius
Chlorotoxin does not inhibit volume-regulated, calcium-activated and cyclic AMP-activated chloride channels.
British journal of pharmacology 2000;129(4):791-801.
2000: Bernd Nilius; Jean Prenen; M P Walsh; Iris Carton; M Bollen; Guy Droogmans; Jan Eggermont
Myosin light chain phosphorylation-dependent modulation of volume-regulated anion channels in macrovascular endothelium.
FEBS letters 2000;466(2-3):346-50.
2000: S H Suh; Guy Droogmans; Bernd Nilius
Effects of cyanide and deoxyglucose on Ca2+ signalling in macrovascular endothelial cells.
Endothelium : journal of endothelial cell research 2000;7(3):155-68.
1999: L Wei; Anne Vankeerberghen; Harry Cuppens; Jan Eggermont; Jean-Jacques Cassiman; Guy Droogmans; Bernd Nilius
Interaction between calcium-activated chloride channels and the cystic fibrosis transmembrane conductance regulator.
Pflügers Archiv : European journal of physiology 1999;438(5):635-41.
1999: Suk H Suh; Rudi Vennekens; VG Manolopoulos; Marc Freichel; U Schweig; Jean Prenen; Veit Flockerzi; Guy Droogmans; Bernd Nilius
Characterisation of explanted endothelial cells from mouse aorta: electrophysiology and Ca2+ signalling.
Pflügers Archiv : European journal of physiology 1999;438(5):612-20.
1999: Dominique Trouet; Bernd Nilius; A Jacobs; C Remacle; Guy Droogmans; Jan Eggermont
Caveolin-1 modulates the activity of the volume-regulated chloride channel.
The Journal of physiology 1999;520 Pt 1():113-9.
1999: Guy Droogmans; Chantal Maertens; Jean Prenen; Bernd Nilius
Sulphonic acid derivatives as probes of pore properties of volume-regulated anion channels in endothelial cells.
British journal of pharmacology 1999;128(1):35-40.
1999: M Kamouchi; Stephan E Philipp; Veit Flockerzi; Ulrich Wissenbach; A Mamin; Luc Raeymaekers; Jan Eggermont; Guy Droogmans; Bernd Nilius
Properties of heterologously expressed hTRP3 channels in bovine pulmonary artery endothelial cells.
The Journal of physiology 1999;518 Pt 2():345-58.
1999: M Kamouchi; Guy Droogmans; Bernd Nilius
Membrane potential as a modulator of the free intracellular Ca2+ concentration in agonist-activated endothelial cells.
General physiology and biophysics 1999;18(2):199-208.
1999: M Kamouchi; A Mamin; Guy Droogmans; Bernd Nilius
Nonselective cation channels in endothelial cells derived from human umbilical vein.
The Journal of membrane biology 1999;169(1):29-38.
1999: Thomas Voets; Guy Droogmans; G Raskin; Jan Eggermont; Bernd Nilius
Reduced intracellular ionic strength as the initial trigger for activation of endothelial volume-regulated anion channels.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5298-303.
1999: Bernd Nilius; Thomas Voets; Jean Prenen; H Barth; Klaus Aktories; K Kaibuchi; Guy Droogmans; Jan Eggermont
Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells.
The Journal of physiology 1999;516 ( Pt 1)():67-74.
1999: Rudi Vennekens; Dominique Trouet; Anne Vankeerberghen; Thomas Voets; Harry Cuppens; Jan Eggermont; Jean-Jacques Cassiman; Guy Droogmans; Bernd Nilius
Inhibition of volume-regulated anion channels by expression of the cystic fibrosis transmembrane conductance regulator.
The Journal of physiology 1999;515 ( Pt 1)():75-85.
1999: Chantal Maertens; L Wei; Thomas Voets; Guy Droogmans; Bernd Nilius
Block by fluoxetine of volume-regulated anion channels.
British journal of pharmacology 1999;126(2):508-14.
1998: L Wei; Anne Vankeerberghen; Harry Cuppens; Guy Droogmans; Jean-Jacques Cassiman; Bernd Nilius
Phosphorylation site independent single R-domain mutations affect CFTR channel activity.
FEBS letters 1998;439(1-2):121-6.
1998: Bernd Nilius; Jean Prenen; Guy Droogmans
Modulation of volume-regulated anion channels by extra- and intracellular pH.
Pflügers Archiv : European journal of physiology 1998;436(5):742-8.
1998: Guy Droogmans; Jean Prenen; Jan Eggermont; Thomas Voets; Bernd Nilius
Voltage-dependent block of endothelial volume-regulated anion channels by calix[4]arenes.
The American journal of physiology 1998;275(3 Pt 1):C646-52.
1998: Felix Viana; Humbert De Smedt; Guy Droogmans; Bernd Nilius
Calcium signalling through nucleotide receptor P2Y2 in cultured human vascular endothelium.
Cell calcium 1998;24(2):117-27.
1998: Thomas Voets; Gunnar Buyse; Guy Droogmans; Jan Eggermont; Bernd Nilius
The GXGXG motif in the pI(Cln) protein is not important for the nucleotide sensitivity of the pI(Cln)-induced Cl- current in Xenopus oocytes.
FEBS letters 1998;426(2):171-3.
1998: Jan Eggermont; Gunnar Buyse; Thomas Voets; Jan Tytgat; Guy Droogmans; Bernd Nilius
Is there a link between protein pICln and volume-regulated anion channels?
The Biochemical journal 1998;331 ( Pt 1)():347-9.
1998: Bernd Nilius; Jean Prenen; Thomas Voets; Jan Eggermont; Karol S Bruzik; Stephen B Shears; Guy Droogmans
Inhibition by inositoltetrakisphosphates of calcium- and volume-activated Cl- currents in macrovascular endothelial cells.
Pflügers Archiv : European journal of physiology 1998;435(5):637-44.
1998: Gunnar Buyse; Dominique Trouet; Thomas Voets; Ludwig Missiaen; Guy Droogmans; Bernd Nilius; Jan Eggermont
Evidence for the intracellular location of chloride channel (ClC)-type proteins: co-localization of ClC-6a and ClC-6c with the sarco/endoplasmic-reticulum Ca2+ pump SERCA2b.
The Biochemical journal 1998;330 ( Pt 2)():1015-21.
1998: Bernd Nilius; Jean Prenen; Thomas Voets; Jan Eggermont; Guy Droogmans
Activation of volume-regulated chloride currents by reduction of intracellular ionic strength in bovine endothelial cells.
The Journal of physiology 1998;506 ( Pt 2)():353-61.
1998: Thomas Voets; VG Manolopoulos; Jan Eggermont; C Ellory; Guy Droogmans; Bernd Nilius
Regulation of a swelling-activated chloride current in bovine endothelium by protein tyrosine phosphorylation and G proteins.
The Journal of physiology 1998;506 ( Pt 2)():341-52.
1998: Harry Cuppens; W Lin; Martine Jaspers; Bruno Costes; H Teng; Anne Vankeerberghen; Mark Jorissen; Guy Droogmans; I Reynaert; Michel Goossens; Bernd Nilius; Jean-Jacques Cassiman
Polyvariant mutant cystic fibrosis transmembrane conductance regulator genes. The polymorphic (Tg)m locus explains the partial penetrance of the T5 polymorphism as a disease mutation.
The Journal of clinical investigation 1998;101(2):487-96.
1997: M Kamouchi; Dominique Trouet; C De Greef; Guy Droogmans; Jan Eggermont; Bernd Nilius
Functional effects of expression of hslo Ca2+ activated K+ channels in cultured macrovascular endothelial cells.
Cell calcium 1997;22(6):497-506.
1997: M Kamouchi; K Van Den Bremt; Jan Eggermont; Guy Droogmans; Bernd Nilius
Modulation of inwardly rectifying potassium channels in cultured bovine pulmonary artery endothelial cells.
The Journal of physiology 1997;504 ( Pt 3)():545-56.
1997: Felix Viana; Ludo Van Den Bosch; Ludwig Missiaen; Wim Vandenberghe; Guy Droogmans; Bernd Nilius; Wim Robberecht
Mibefradil (Ro 40-5967) blocks multiple types of voltage-gated calcium channels in cultured rat spinal motoneurones.
Cell calcium 1997;22(4):299-311.
1997: Thomas Voets; Guy Droogmans; Bernd Nilius
Modulation of voltage-dependent properties of a swelling-activated Cl- current.
The Journal of general physiology 1997;110(3):313-25.
1997: Dominique Trouet; Bernd Nilius; Thomas Voets; Guy Droogmans; Jan Eggermont
Use of a bicistronic GFP-expression vector to characterise ion channels after transfection in mammalian cells.
Pflügers Archiv : European journal of physiology 1997;434(5):632-8.
1997: VG Manolopoulos; Thomas Voets; Peter E Declercq; Guy Droogmans; Bernd Nilius
Swelling-activated efflux of taurine and other organic osmolytes in endothelial cells.
The American journal of physiology 1997;273(1 Pt 1):C214-22.
1997: Bernd Nilius; Jean Prenen; Thomas Voets; K Van den Bremt; Jan Eggermont; Guy Droogmans
Kinetic and pharmacological properties of the calcium-activated chloride-current in macrovascular endothelial cells.
Cell calcium 1997;22(1):53-63.
1997: Jan Eggermont; Gunnar Buyse; Thomas Voets; Jan Tytgat; Humbert De Smedt; Guy Droogmans; Bernd Nilius
Alternative splicing of ClC-6 (a member of the CIC chloride-channel family) transcripts generates three truncated isoforms one of which, ClC-6c, is kidney-specific.
The Biochemical journal 1997;325 ( Pt 1)():269-76.
1997: Bernd Nilius; Jean Prenen; M Kamouchi; Felix Viana; Thomas Voets; Guy Droogmans
Inhibition by mibefradil, a novel calcium channel antagonist, of Ca(2+)- and volume-activated Cl- channels in macrovascular endothelial cells.
British journal of pharmacology 1997;121(3):547-55.
1997: Bernd Nilius; G Szücs; S Heinke; Thomas Voets; Guy Droogmans
Multiple types of chloride channels in bovine pulmonary artery endothelial cells.
Journal of vascular research 1997;34(3):220-8.
1997: M Haburcák; L Wei; Felix Viana; Jean Prenen; Guy Droogmans; Bernd Nilius
Calcium-activated potassium channels in cultured human endothelial cells are not directly modulated by nitric oxide.
Cell calcium 1997;21(4):291-300.
1997: G V Manolopoulos; Jean Prenen; Guy Droogmans; Bernd Nilius
Thrombin potentiates volume-activated chloride currents in pulmonary artery endothelial cells.
Pflügers Archiv : European journal of physiology 1997;433(6):845-7.
1997: VG Manolopoulos; Guy Droogmans; Bernd Nilius
Hypotonicity and thrombin activate taurine efflux in BC3H1 and C2C12 myoblasts that is down regulated during differentiation.
Biochemical and biophysical research communications 1997;232(1):74-9.
1997: Gunnar Buyse; Thomas Voets; Jan Tytgat; C De Greef; Guy Droogmans; Bernd Nilius; Jan Eggermont
Expression of human pICln and ClC-6 in Xenopus oocytes induces an identical endogenous chloride conductance.
The Journal of biological chemistry 1997;272(6):3615-21.
1997: Thomas Voets; L Wei; Patrick De Smet; Willy Van Driessche; Jan Eggermont; Guy Droogmans; Bernd Nilius
Downregulation of volume-activated Cl- currents during muscle differentiation.
The American journal of physiology 1997;272(2 Pt 1):C667-74.
1997: Bernd Nilius; Jean Prenen; G Szücs; L Wei; F Tanzi; Thomas Voets; Guy Droogmans
Calcium-activated chloride channels in bovine pulmonary artery endothelial cells.
The Journal of physiology 1997;498 ( Pt 2)():381-96.
1997: Bernd Nilius; Jan Eggermont; Thomas Voets; Gunnar Buyse; VG Manolopoulos; Guy Droogmans
Properties of volume-regulated anion channels in mammalian cells.
Progress in biophysics and molecular biology 1997;68(1):69-119.
1997: Bernd Nilius; Felix Viana; Guy Droogmans
Ion channels in vascular endothelium.
Annual review of physiology 1997;59():145-70.
1996: Bernd Nilius; Volker Gerke; Jean Prenen; G Szücs; S Heinke; K Weber; Guy Droogmans
Annexin II modulates volume-activated chloride currents in vascular endothelial cells.
The Journal of biological chemistry 1996;271(48):30631-6.
1996: Thomas Voets; Guy Droogmans; Bernd Nilius
Membrane currents and the resting membrane potential in cultured bovine pulmonary artery endothelial cells.
The Journal of physiology 1996;497 ( Pt 1)():95-107.
1996: Thomas Voets; Gunnar Buyse; Jan Tytgat; Guy Droogmans; Jan Eggermont; Bernd Nilius
The chloride current induced by expression of the protein pICln in Xenopus oocytes differs from the endogenous volume-sensitive chloride current.
The Journal of physiology 1996;495 ( Pt 2)():441-7.
1996: Thomas Voets; Guy Droogmans; Bernd Nilius
Potent block of volume-activated chloride currents in endothelial cells by the uncharged form of quinine and quinidine.
British journal of pharmacology 1996;118(7):1869-71.
1996: Ludwig Missiaen; Humbert De Smedt; Jan B Parys; Luc Raeymaekers; Guy Droogmans; Ludo Van Den Bosch; Rik Casteels
Kinetics of the non-specific calcium leak from non-mitochondrial calcium stores in permeabilized A7r5 cells.
The Biochemical journal 1996;317 ( Pt 3)():849-53.
1996: Jan Tytgat; Gunnar Buyse; Jan Eggermont; Guy Droogmans; Bernd Nilius; P Daenens
Do voltage-gated Kv1.1 and inward rectifier Kir2.1 potassium channels form heteromultimers?
FEBS letters 1996;390(3):280-4.
1996: G Szücs; Gunnar Buyse; Jan Eggermont; Guy Droogmans; Bernd Nilius
Characterization of volume-activated chloride currents in endothelial cells from bovine pulmonary artery.
The Journal of membrane biology 1996;149(3):189-97.
1996: G Szücs; S Heinke; C De Greef; Luc Raeymaekers; Jan Eggermont; Guy Droogmans; Bernd Nilius
The volume-activated chloride current in endothelial cells from bovine pulmonary artery is not modulated by phosphorylation.
Pflügers Archiv : European journal of physiology 1996;431(4):540-8.
1996: Gunnar Buyse; C De Greef; Luc Raeymaekers; Guy Droogmans; Bernd Nilius; Jan Eggermont
The ubiquitously expressed pICln protein forms homomeric complexes in vitro.
Biochemical and biophysical research communications 1996;218(3):822-7.
1996: G Szücs; S Heinke; Guy Droogmans; Bernd Nilius
Activation of the volume-sensitive chloride current in vascular endothelial cells requires a permissive intracellular Ca2+ concentration.
Pflügers Archiv : European journal of physiology 1996;431(3):467-9.
1995: Thomas Voets; G Szücs; Guy Droogmans; Bernd Nilius
Blockers of volume-activated Cl- currents inhibit endothelial cell proliferation.
Pflügers Archiv : European journal of physiology 1995;431(1):132-4.
1995: Bernd Nilius; J Sehrer; Patrick De Smet; Willy Van Driessche; Guy Droogmans
Volume regulation in a toad epithelial cell line: role of coactivation of K+ and Cl- channels.
The Journal of physiology 1995;487 ( Pt 2)():367-78.
1995: S Heinke; G Szücs; A Norris; Guy Droogmans; Bernd Nilius
Inhibition of volume-activated chloride currents in endothelial cells by chromones.
British journal of pharmacology 1995;115(8):1393-8.
1995: Bernd Nilius; J Sehrer; S Heinke; Guy Droogmans
Ca2+ release and activation of K+ and Cl- currents by extracellular ATP in distal nephron epithelial cells.
The American journal of physiology 1995;269(2 Pt 1):C376-84.
1995: C De Greef; S van der Heyden; Felix Viana; Jan Eggermont; Ernst A de Bruijn; Luc Raeymaekers; Guy Droogmans; Bernd Nilius
Lack of correlation between mdr-1 expression and volume-activation of cloride-currents in rat colon cancer cells.
Pflügers Archiv : European journal of physiology 1995;430(2):296-8.
1995: C De Greef; J Sehrer; Felix Viana; K van Acker; Jan Eggermont; Luc Mertens; Luc Raeymaekers; Guy Droogmans; Bernd Nilius
Volume-activated chloride currents are not correlated with P-glycoprotein expression.
The Biochemical journal 1995;307 ( Pt 3)():713-8.
1995: Felix Viana; K Van Acker; C De Greef; Jan Eggermont; Luc Raeymaekers; Guy Droogmans; Bernd Nilius
Drug-transport and volume-activated chloride channel functions in human erythroleukemia cells: relation to expression level of P-glycoprotein.
The Journal of membrane biology 1995;145(1):87-98.
1995: M Gericke; O Dar; Guy Droogmans; I Pecht; Bernd Nilius
Immunological stimulation of single rat basophilic leukemia RBL-2H3 cells co-activates Ca(2+)-entry and K(+)-channels.
Cell calcium 1995;17(1):71-83.
1994: M Gericke; M Oike; Guy Droogmans; Bernd Nilius
Inhibition of capacitative Ca2+ entry by a Cl- channel blocker in human endothelial cells.
European journal of pharmacology 1994;269(3):381-4.
1994: M Oike; M Gericke; Guy Droogmans; Bernd Nilius
Calcium entry activated by store depletion in human umbilical vein endothelial cells.
Cell calcium 1994;16(5):367-76.
1994: M Oike; G Schwarz; J Sehrer; M Jost; Volker Gerke; K Weber; Guy Droogmans; Bernd Nilius
Cytoskeletal modulation of the response to mechanical stimulation in human vascular endothelial cells.
Pflügers Archiv : European journal of physiology 1994;428(5-6):569-76.
1994: Bernd Nilius; J Sehrer; Felix Viana; C De Greef; Luc Raeymaekers; Jan Eggermont; Guy Droogmans
Volume-activated Cl- currents in different mammalian non-excitable cell types.
Pflügers Archiv : European journal of physiology 1994;428(3-4):364-71.
1994: Patrick De Smet; M Oike; Guy Droogmans; Willy Van Driessche; Bernd Nilius
Responses of endothelial cells to hypotonic solutions: lack of regulatory volume decrease.
Pflügers Archiv : European journal of physiology 1994;428(1):94-6.
1994: Bernd Nilius; J Sehrer; Guy Droogmans
Permeation properties and modulation of volume-activated Cl(-)-currents in human endothelial cells.
British journal of pharmacology 1994;112(4):1049-56.
1994: M Oike; Guy Droogmans; Bernd Nilius
Amplitude modulation of Ca2+ signals induced by histamine in human endothelial cells.
Biochimica et biophysica acta 1994;1222(2):287-91.
1994: Bernd Nilius; M Oike; Ivan Zahradník; Guy Droogmans
Activation of a Cl- current by hypotonic volume increase in human endothelial cells.
The Journal of general physiology 1994;103(5):787-805.
1994: M Oike; Guy Droogmans; Bernd Nilius
Mechanosensitive Ca2+ transients in endothelial cells from human umbilical vein.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):2940-4.
1994: G Schwarz; Guy Droogmans; Bernd Nilius
Multiple effects of SK&F 96365 on ionic currents and intracellular calcium in human endothelial cells.
Cell calcium 1994;15(1):45-54.
1993: Bernd Nilius; G Schwarz; Guy Droogmans
Control of intracellular calcium by membrane potential in human melanoma cells.
The American journal of physiology 1993;265(6 Pt 1):C1501-10.
1993: Bernd Nilius; G Schwarz; Guy Droogmans
Modulation by histamine of an inwardly rectifying potassium channel in human endothelial cells.
The Journal of physiology 1993;472():359-71.
1993: Bernd Nilius; G Schwartz; M Oike; Guy Droogmans
Histamine-activated, non-selective cation currents and Ca2+ transients in endothelial cells from human umbilical vein.
Pflügers Archiv : European journal of physiology 1993;424(3-4):285-93.
1993: Bernd Nilius; Guy Droogmans; M Gericke; G Schwarz
Nonselective ion pathways in human endothelial cells.
EXS 1993;66():269-80.
1992: Ludwig Missiaen; Humbert De Smedt; Guy Droogmans; Rik Casteels
2,5-Di-(tert-butyl)-1,4-benzohydroquinone and cyclopiazonic acid decrease the Ca2+ permeability of endoplasmic reticulum.
European journal of pharmacology 1992;227(4):391-4.
1992: M L Lydrup; Bernard Himpens; Guy Droogmans; Per Hellstrand; A P Somlyo
Paradoxical decrease in cytosolic calcium with increasing depolarization by potassium in guinea-pig mesotubarium smooth muscle.
Pflügers Archiv : European journal of physiology 1992;420(5-6):428-33.
1991: Ludwig Missiaen; Humbert De Smedt; Guy Droogmans; I Declerck; L Plessers; Rik Casteels
Uptake characteristics of the InsP3-sensitive and -insensitive Ca2+ pools in porcine aortic smooth-muscle cells: different Ca2+ sensitivity of the Ca2(+)-uptake mechanism.
Biochemical and biophysical research communications 1991;174(3):1183-8.
1991: Bernard Himpens; Ludwig Missiaen; Guy Droogmans; Rik Casteels
AlF4- induces Ca2+ oscillations in guinea-pig ileal smooth muscle.
Pflügers Archiv : European journal of physiology 1991;417(6):645-50.
1991: Guy Droogmans; Geert Callewaert; I Declerck; Rik Casteels
ATP-induced Ca2+ release and Cl- current in cultured smooth muscle cells from pig aorta.
The Journal of physiology 1991;440():623-34.
1990: I Declerck; Bernard Himpens; Guy Droogmans; Rik Casteels
The alpha 1-agonist phenylephrine inhibits voltage-gated Ca2(+)-channels in vascular smooth muscle cells of rabbit ear artery.
Pflügers Archiv : European journal of physiology 1990;417(1):117-9.
1990: Ludwig Missiaen; I Declerck; Guy Droogmans; L Plessers; Humbert De Smedt; Luc Raeymaekers; Rik Casteels
Agonist-dependent Ca2+ and Mn2+ entry dependent on state of filling of Ca2+ stores in aortic smooth muscle cells of the rat.
The Journal of physiology 1990;427():171-86.
1990: Ludwig Missiaen; Humbert De Smedt; Guy Droogmans; Frank Wuytack; Luc Raeymaekers; Rik Casteels
Ruthenium red and compound 48/80 inhibit the smooth-muscle plasma-membrane Ca2+ pump via interaction with associated polyphosphoinositides.
Biochimica et biophysica acta 1990;1023(3):449-54.
1989: Guy Droogmans; Bernd Nilius
Kinetic properties of the cardiac T-type calcium channel in the guinea-pig.
The Journal of physiology 1989;419():627-50.
1989: Ludwig Missiaen; Y Kanmura; Frank Wuytack; Luc Raeymaekers; I Declerck; Guy Droogmans; Rik Casteels
AlF-4 inhibits the accumulation of Ca in the endoplasmic reticulum in intact myometrial strips, but not in the rabbit ear artery.
Pflügers Archiv : European journal of physiology 1989;414(4):423-9.