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Yigal Dror

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Santhosh Dhanraj; Runjan Chetty; Helen Favre; Mignon L Loh; Arif Manji; Dalila Pinto; Stephen W Scherer; Alice C Wei; Yigal Dror
Molecular characteristics of a pancreatic adenocarcinoma associated with Shwachman-Diamond syndrome.
Yigal Dror; Peter Durie; Elizabeth Kerr; Jutta Koglmeier; Taco Kuijpers; Outi Makitie; Johanna M Rommens; Neil Shah; Akiko Shimamura; Liesbeth Siderius; Sanna Toiviainen-Salo; Cornelia Zeidler; Marco Cipolli; John Dodge; jean donadieu; Johnson Ming-Yu Liu
Draft consensus guidelines for diagnosis and treatment of Shwachman-Diamond syndrome.
E Tsangaris; R Yanofsky; S Abish; K Ali; C Allen; Uma H Athale; Joseph Beyene; J Brossard; Patricia Canning; Manuel Carcao; J Champagne; N Dower; Conrad V Fernandez; J P Hand; L Jardine; R Klaassen; J H Lipton; B Michon; Isaac Odame; Chaim M Roifman; E Shereck; Mariana Silva; M Steele; Yigal Dror
Genetic analysis of inherited bone marrow failure syndromes from one prospective, comprehensive and population-based cohort and identification of novel mutations.

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All Publications

2013: Santhosh Dhanraj; Runjan Chetty; Helen Favre; Mignon L Loh; Arif Manji; Dalila Pinto; Stephen W Scherer; Alice C Wei; Yigal Dror
Molecular characteristics of a pancreatic adenocarcinoma associated with Shwachman-Diamond syndrome.
Pediatric blood & cancer 2013;60(5):754-60.
2011: Yigal Dror; Peter Durie; Elizabeth Kerr; Jutta Koglmeier; Taco Kuijpers; Outi Makitie; Johanna M Rommens; Neil Shah; Akiko Shimamura; Liesbeth Siderius; Sanna Toiviainen-Salo; Cornelia Zeidler; Marco Cipolli; John Dodge; jean donadieu; Johnson Ming-Yu Liu
Draft consensus guidelines for diagnosis and treatment of Shwachman-Diamond syndrome.
Annals of the New York Academy of Sciences 2011;1242():40-55.
2011: E Tsangaris; R Yanofsky; S Abish; K Ali; C Allen; Uma H Athale; Joseph Beyene; J Brossard; Patricia Canning; Manuel Carcao; J Champagne; N Dower; Conrad V Fernandez; J P Hand; L Jardine; R Klaassen; J H Lipton; B Michon; Isaac Odame; Chaim M Roifman; E Shereck; Mariana Silva; M Steele; Yigal Dror
Genetic analysis of inherited bone marrow failure syndromes from one prospective, comprehensive and population-based cohort and identification of novel mutations.
Journal of medical genetics 2011;48(9):618-28.
2011: S K Hashmi; C Allen; R Klaassen; Conrad V Fernandez; R Yanofsky; E Shereck; J Champagne; Mariana Silva; J H Lipton; J Brossard; Yvan Samson; S Abish; M Steele; K Ali; N Dower; U Athale; L Jardine; J P Hand; Joseph Beyene; Yigal Dror
Comparative analysis of Shwachman-Diamond syndrome to other inherited bone marrow failure syndromes and genotype-phenotype correlation.
Clinical genetics 2011;79(5):448-58.
2010: Chhaya Ambekar; Bikul Das; Herman Yeger; Yigal Dror
SBDS-deficiency results in deregulation of reactive oxygen species leading to increased cell death and decreased cell growth.
Pediatric blood & cancer 2010;55(6):1138-44.
2009: Vicky Rowena Breakey; M Stephen Meyn; Vicky Ng; Christopher Allen; Inderjeet Dokal; Peter M Lansdorp; Oussama Abla; Yigal Dror
Hepatitis-associated aplastic anemia presenting as a familial bone marrow failure syndrome.
Journal of pediatric hematology/oncology 2009;31(11):884-7.
2009: Paola Angelini; Fotini Kavadas; Navneet Sharma; Susan E Richardson; Graham A Tipples; Chaim M Roifman; Yigal Dror; Yehuda Nofech-Mozes
Aplastic anemia following varicella vaccine.
The Pediatric infectious disease journal 2009;28(8):746-8.
2009: Piya Rujkijyanont; Sally-Lin Adams; Joseph Beyene; Yigal Dror
Bone marrow cells from patients with Shwachman-Diamond syndrome abnormally express genes involved in ribosome biogenesis and RNA processing.
British journal of haematology 2009;145(6):806-15.
2009: Jillian M Baker; Victor A Lewis; Conrad V Fernandez; Michel Duval; Bruce N Crooks; Kim Yuille; Melvin H Freedman; John J Doyle; Yigal Dror
Allogeneic hematopoietic stem cell transplantation of patients with FA and high risk features using fludarabine without radiation.
Pediatric blood & cancer 2009;52(5):683-5.
2009: Christine Macartney; Marshall Freilich; Isaac Odame; Karen Charpentier; Yigal Dror
Complete response to tacrolimus in a child with severe aplastic anemia resistant to cyclosporin A.
Pediatric blood & cancer 2009;52(4):525-7.
2008: Elena Tsangaris; Sally-Lin Adams; Grace Yoon; David Chitayat; Peter Lansdorp; Inderjeet Dokal; Yigal Dror
Ataxia and pancytopenia caused by a mutation in TINF2.
Human genetics 2008;124(5):507-13.
2008: Michelle Rey; Simon P Duffy; Jennifer K Brown; James A Kennedy; John E Dick; Yigal Dror; Chetankumar S Tailor
Enhanced alternative splicing of the FLVCR1 gene in Diamond Blackfan anemia disrupts FLVCR1 expression and function that are critical for erythropoiesis.
Haematologica 2008;93(11):1617-26.
2008: Juliana T Teo; Robert Klaassen; Conrad V Fernandez; Rochelle Yanofsky; John Wu; Josette Champagne; Mariana Silva; Jeffrey H Lipton; Jossee Brossard; Yvan Samson; Sharon Abish; Macgregor Steele; Kaiser Ali; Uma Athale; Lawrence Jardine; John P Hand; Elena Tsangaris; Isaac Odame; Joseph Beyene; Yigal Dror
Clinical and genetic analysis of unclassifiable inherited bone marrow failure syndromes.
Pediatrics 2008;122(1):e139-48.
2008: Piya Rujkijyanont; Ken-Ichiro Watanabe; Chhaya Ambekar; Hanming Wang; Aaron Schimmer; Joseph Beyene; Yigal Dror
SBDS-deficient cells undergo accelerated apoptosis through the Fas-pathway.
Haematologica 2008;93(3):363-71.
2008: Bunchoo Pongtanakul; Prabodh Kumar Das; Karen Charpentier; Yigal Dror
Outcome of children with aplastic anemia treated with immunosuppressive therapy.
Pediatric blood & cancer 2008;50(1):52-7.
2007: Prabodh Kumar Das; Diane Wherrett; Yigal Dror
Remission of aplastic anemia induced by treatment for Graves disease in a pediatric patient.
Pediatric blood & cancer 2007;49(2):210-2.
2007: Piya Rujkijyanont; Joseph Beyene; Kuiru Wei; Fahad Khan; Yigal Dror
Leukaemia-related gene expression in bone marrow cells from patients with the preleukaemic disorder Shwachman-Diamond syndrome.
British journal of haematology 2007;137(6):537-44.
2007: Chrisovalantou Cheretakis; David Locker; Yigal Dror; Glogauer Michael
Oral health-related quality of life of children with neutropenia.
Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry 2007;27(1):6-11.
2007: Lillian Sung; Yigal Dror
Clinical applications of granulocyte-colony stimulating factor.
Frontiers in bioscience : a journal and virtual library 2007;12():1988-2002.
2006: J M Steele; Lillian Sung; R Klaassen; Conrad V Fernandez; R Yanofsky; J Wu; Isaac Odame; Mariana Silva; J Champagne; K Ali; J Brossard; Yvan Samson; S Abish; D Le; L Jardine; J P Hand; J H Lipton; K Charpentier; D Stephens; M Freedman; Yigal Dror
Disease progression in recently diagnosed patients with inherited marrow failure syndromes: a Canadian Inherited Marrow Failure Registry (CIMFR) report.
Pediatric blood & cancer 2006;47(7):918-25.
2006: Chrisovalantou Cheretakis; Roland Leung; Chun Xiang Sun; Yigal Dror; Glogauer Michael
Timing of neutrophil tissue repopulation predicts restoration of innate immune protection in a murine bone marrow transplantation model.
Blood 2006;108(8):2821-6.
2006: Elaine W Leung; Piya Rujkijyanont; Joseph Beyene; Kuiru Wei; Mohamed Abdelhaleem; Melvin H Freedman; Yigal Dror
Shwachman-Diamond syndrome: an inherited model of aplastic anaemia with accelerated angiogenesis.
British journal of haematology 2006;133(5):558-61.
2005: Yigal Dror
Shwachman-Diamond syndrome.
Pediatric blood & cancer 2005;45(7):892-901.
2005: Fidel Majeed; Sergiy Jadko; Melvin H Freedman; Yigal Dror
Mutation analysis of SBDS in pediatric acute myeloblastic leukemia.
Pediatric blood & cancer 2005;45(7):920-4.
2005: Chrisovalantou Cheretakis; Yigal Dror; Glogauer Michael
A noninvasive oral rinse assay to monitor engraftment, neutrophil tissue delivery and susceptibility to infection following HSCT in pediatric patients.
Bone marrow transplantation 2005;36(3):227-32.
2005: Macgregor Steele; Johann K Hitzler; John J Doyle; Manuela Germeshausen; Conrad V Fernandez; Kim Yuille; Yigal Dror
Reduced intensity hematopoietic stem-cell transplantation across human leukocyte antigen barriers in a patient with congenital amegakaryocytic thrombocytopenia and monosomy 7.
Pediatric blood & cancer 2005;45(2):212-6.
2005: Adam Gassas; John J Doyle; Sheila Weitzman; Melvin H Freedman; Johann K Hitzler; Anjali Sharathkumar; Yigal Dror
A basic classification and a comprehensive examination of pediatric myeloproliferative syndromes.
Journal of pediatric hematology/oncology 2005;27(4):192-6.
2004: Yigal Dror; Eyal Grunebaum; Johann K Hitzler; Aru Narendran; Charles Ye; Raymond Tellier; Vernon Edwards; Melvin H Freedman; Chaim M Roifman
Purine nucleoside phosphorylase deficiency associated with a dysplastic marrow morphology.
Pediatric research 2004;55(3):472-7.
2004: Anjali Sharathkumar; E Fred Saunders; Yigal Dror; R Grant; M Greenberg; S Weitzman; H Chan; Stan Calderwood; Melvin H Freedman; John Doyle
Allogeneic bone marrow transplantation vs chemotherapy for children with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Bone marrow transplantation 2004;33(1):39-45.
2003: Adam Gassas; Melvin H Freedman; Karen Mandel; Yigal Dror
Reply to Hasle et al.
Leukemia 2003;17(12):2531-2; author reply 2532.
2003: Nicola A M Bobey; Manuel Carcao; Yigal Dror; Melvin H Freedman; Niklas Dahl; Richard C Woodman
Sustained cyclosporine-induced erythropoietic response in identical male twins with diamond-blackfan anemia.
Journal of pediatric hematology/oncology 2003;25(11):914-8.
2003: Elaine W Leung; Richard C Woodman; Birgitte Roland; Mohamed Abdelhaleem; Melvin H Freedman; Yigal Dror
Transient myelodysplastic syndrome associated with isochromosome 7q abnormality.
Pediatric hematology and oncology 2003;20(7):539-45.
2003: Anjali Sharathkumar; Melanie Kirby; Melvin Freedman; Mohamed Abdelhaleem; David Chitayat; Ikuko E Teshima; Yigal Dror
Malignant hematological disorders in children with Wolf-Hirschhorn syndrome.
American journal of medical genetics. Part A 2003;119A(2):194-9.
2003: Yigal Dror; Melvin H Freedman; M Leaker; J Verbeek; C A Armstrong; Frederick E Saunders; John J Doyle
Low-intensity hematopoietic stem-cell transplantation across human leucocyte antigen barriers in dyskeratosis congenita.
Bone marrow transplantation 2003;31(10):847-50.
2003: Yigal Dror
The role of mitochondrial-mediated apoptosis in a myelodysplastic syndrome secondary to congenital deletion of the short arm of chromosome 4.
Experimental hematology 2003;31(3):211-7.
2003: Elaine W Leung; Wilma Vanek; Mohamed Abdelhaleem; Melvin H Freedman; Yigal Dror
The evolution of juvenile myelomonocytic leukemia in a female patient with paternally inherited neurofibromatosis type 1.
Journal of pediatric hematology/oncology 2003;25(2):145-7.
2002: Karen Mandel; Yigal Dror; Annette Poon; Melvin H Freedman
A practical, comprehensive classification for pediatric myelodysplastic syndromes: the CCC system.
Journal of pediatric hematology/oncology 2002;24(7):596-605.
2002: Yigal Dror; Melvin H Freedman
Shwachman-diamond syndrome.
British journal of haematology 2002;118(3):701-13.
2002: Yigal Dror; Peter Roy Durie; Hedy H Ginzberg; Rebecca Herman; Anu Banerjee; Martin Champagne; Kevin Shannon; David Malkin; Melvin H Freedman
Clonal evolution in marrows of patients with Shwachman-Diamond syndrome: a prospective 5-year follow-up study.
Experimental hematology 2002;30(7):659-69.
2002: Karen Mandel; Yigal Dror; Annette Poon; Melvin H Freedman
A practical, comprehensive classification for pediatric myelodysplastic syndromes: the CCC system.
Journal of pediatric hematology/oncology 2002;24(5):343-52.
2002: Ian Thornley; Yigal Dror; Lillian Sung; Rob F Wynn; Melvin H Freedman
Abnormal telomere shortening in leucocytes of children with Shwachman-Diamond syndrome.
British journal of haematology 2002;117(1):189-92.
2001: Yigal Dror; Hedy H Ginzberg; Ilan Dalal; Vera Cherepanov; G Downey; Peter Roy Durie; Chaim M Roifman; Melvin H Freedman
Immune function in patients with Shwachman-Diamond syndrome.
British journal of haematology 2001;114(3):712-7.
2001: Yigal Dror; Melvin H Freedman
Shwachman-Diamond syndrome marrow cells show abnormally increased apoptosis mediated through the Fas pathway.
Blood 2001;97(10):3011-6.
2000: Yigal Dror; Alister Ward; Ivo P Touw; Melvin H Freedman
Combined corticosteroid/granulocyte colony-stimulating factor (G-CSF) therapy in the treatment of severe congenital neutropenia unresponsive to G-CSF: Activated glucocorticoid receptors synergize with G-CSF signals.
Experimental hematology 2000;28(12):1381-9.
2000: A H al-Jefri; Yigal Dror; J B Bussel; Melvin H Freedman
Thrombocytopenia with absent radii: frequency of marrow megakaryocyte progenitors, proliferative characteristics, and megakaryocyte growth and development factor responsiveness.
Pediatric hematology and oncology 2000;17(4):299-306.
2000: Yigal Dror; M Leaker; G Caruana; A Bernstein; Melvin H Freedman
Mastocytosis cells bearing a c-kit activating point mutation are characterized by hypersensitivity to stem cell factor and increased apoptosis.
British journal of haematology 2000;108(4):729-36.
1999: Yigal Dror; Victor S Blanchette
Essential thrombocythaemia in children.
British journal of haematology 1999;107(4):691-8.
1999: Yigal Dror; Alvin Zipursky; Victor S Blanchette
Essential thrombocythemia in children.
Journal of pediatric hematology/oncology 1999;21(5):356-63.
1999: Hedy H Ginzberg; J Shin; Lynda Ellis; Jodi Morrison; W Ip; Yigal Dror; M Freedman; L A Heitlinger; M A Belt; Mary Corey; Johanna M Rommens; Peter Roy Durie
Shwachman syndrome: phenotypic manifestations of sibling sets and isolated cases in a large patient cohort are similar.
The Journal of pediatrics 1999;135(1):81-8.
1998: Yigal Dror; J Squire; Peter Roy Durie; Melvin H Freedman
Malignant myeloid transformation with isochromosome 7q in Shwachman-Diamond syndrome.
Leukemia 1998;12(10):1591-5.
1998: Yigal Dror; Peter Roy Durie; P Marcon; Melvin H Freedman
Duplication of distal thumb phalanx in Shwachman-Diamond syndrome.
American journal of medical genetics 1998;78(1):67-9.