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Stavit Drori

Research Profile

Chemicals & Drugs

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Leukemia

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Publications

TOP 3
Roy I Pinhassi; Yehuda G Assaraf; Shimon Farber; Michal Stark; Diana Ickowicz; Stavit Drori; Abraham J Domb; Yoav D Livney
Arabinogalactan-folic acid-drug conjugate for targeted delivery and target-activated release of anticancer drugs to folate receptor-overexpressing cells.
Inbal Lasry; Bluma Berman; Rachel Straussberg; Yael Sofer; Hanna Bessler; Mohamad Sharkia; Fabian Glaser; Gerrit Jansen; Stavit Drori; Yehuda G Assaraf
A novel loss-of-function mutation in the proton-coupled folate transporter from a patient with hereditary folate malabsorption reveals that Arg 113 is crucial for function.
Julie St-Pierre; Stavit Drori; Marc Uldry; Jessica M Silvaggi; James Rhee; Sibylle Jäger; Christoph Handschin; Kangni Zheng; Jiandie Lin; Wenli Yang; David K Simon; Robert Bachoo; Bruce M Spiegelman
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators.

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All Publications

2010: Roy I Pinhassi; Yehuda G Assaraf; Shimon Farber; Michal Stark; Diana Ickowicz; Stavit Drori; Abraham J Domb; Yoav D Livney
Arabinogalactan-folic acid-drug conjugate for targeted delivery and target-activated release of anticancer drugs to folate receptor-overexpressing cells.
Biomacromolecules 2010;11(1):294-303.
2008: Inbal Lasry; Bluma Berman; Rachel Straussberg; Yael Sofer; Hanna Bessler; Mohamad Sharkia; Fabian Glaser; Gerrit Jansen; Stavit Drori; Yehuda G Assaraf
A novel loss-of-function mutation in the proton-coupled folate transporter from a patient with hereditary folate malabsorption reveals that Arg 113 is crucial for function.
Blood 2008;112(5):2055-61.
2006: Julie St-Pierre; Stavit Drori; Marc Uldry; Jessica M Silvaggi; James Rhee; Sibylle Jäger; Christoph Handschin; Kangni Zheng; Jiandie Lin; Wenli Yang; David K Simon; Robert Bachoo; Bruce M Spiegelman
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators.
Cell 2006;127(2):397-408.
2005: Stavit Drori; Geoffrey D Girnun; Liqiang Tou; Jeffrey D Szwaya; Elisabetta Mueller; Kai Xia; Xia Kia; Ramesh A Shivdasani; Bruce M Spiegelman
Hic-5 regulates an epithelial program mediated by PPARgamma.
Genes & development 2005;19(3):362-75.
2004: Yotam Kaufman; Stavit Drori; Peter Cole; Barton A. Kamen; Jenny Sirota; Ilan Ifergan; Myriam Weyl Ben Arush; Ronit Elhasid; Dvora Sahar; G J L Kaspers; Gerrit Jansen; Larry H Matherly; Gideon Rechavi; Amos Toren; Yehuda G Assaraf
Reduced folate carrier mutations are not the mechanism underlying methotrexate resistance in childhood acute lymphoblastic leukemia.
Cancer 2004;100(4):773-82.
2003: Dana Baron; Yehuda G Assaraf; Stavit Drori; Ami Aronheim
Disruption of transport activity in a D93H mutant thiamine transporter 1, from a Rogers Syndrome family.
European journal of biochemistry / FEBS 2003;270(22):4469-77.
2002: Elisabetta Mueller; Stavit Drori; Anita Aiyer; Junming Yie; pasha sarraf; Hong Chen; Stefanie Hauser; Evan D Rosen; Kai Ge; Robert G Roeder; Bruce M Spiegelman
Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor gamma isoforms.
The Journal of biological chemistry 2002;277(44):41925-30.
2002: Geoffrey D Girnun; Wendy M Smith; Stavit Drori; pasha sarraf; Elisabetta Mueller; Charis Eng; Prashant R Nambiar; Daniel W Rosenberg; Roderick T Bronson; Winfried Edelmann; Raju Kucherlapati; Frank J Gonzalez; Bruce M Spiegelman
APC-dependent suppression of colon carcinogenesis by PPARgamma.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13771-6.
2002: Robert Mauritz; Godefridus J Peters; David G Priest; Yehuda G Assaraf; Stavit Drori; Ietje Kathmann; Paul Noordhuis; Marlene A Bunni; Andre Rosowsky; Jan H Schornagel; HERBERT PINEDO; Gerrit Jansen
Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
Biochemical pharmacology 2002;63(2):105-15.
2000: Stavit Drori; Gerrit Jansen; Robert Mauritz; Godefridus J Peters; Yehuda G Assaraf
Clustering of mutations in the first transmembrane domain of the human reduced folate carrier in GW1843U89-resistant leukemia cells with impaired antifolate transport and augmented folate uptake.
The Journal of biological chemistry 2000;275(40):30855-63.
2000: Stavit Drori; Hannah Sprecher; G Shemer; Gerrit Jansen; I David Goldman; Yehuda G Assaraf
Characterization of a human alternatively spliced truncated reduced folate carrier increasing folate accumulation in parental leukemia cells.
European journal of biochemistry / FEBS 2000;267(3):690-702.
1998: Eli Sprecher; Reuven Bergman; Hannah Sprecher; Gila Maor; Irena Reiter; Norberto Krivoy; Stavit Drori; Yehuda G Assaraf; Rachel Friedman-Birnbaum
Reduced folate carrier (RFC-1) gene expression in normal and psoriatic skin.
Archives of dermatological research 1998;290(12):656-60.
1998: Gerrit Jansen; Robert Mauritz; Stavit Drori; Hannah Sprecher; Ietje Kathmann; Marlene A Bunni; David G Priest; Paul Noordhuis; Jan H Schornagel; HERBERT PINEDO; Godefridus J Peters; Yehuda G Assaraf
A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.
The Journal of biological chemistry 1998;273(46):30189-98.
1998: Eli Sprecher; Reuven Bergman; Hannah Sprecher; Gila Maor; Irena Reiter; Norberto Krivoy; Stavit Drori; Yehuda G Assaraf; Rachel Friedman-Birnbaum
The reduced folate carrier (RFC-1) gene is expressed in the murine epidermis.
Archives of dermatological research 1998;290(7):394-6.
1997: Gerrit Jansen; Robert Mauritz; Yehuda G Assaraf; Hannah Sprecher; Stavit Drori; Ietje Kathmann; G R Westerhof; David G Priest; Marlene A Bunni; HERBERT PINEDO; Jan H Schornagel; Godefridus J Peters
Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells.
Advances in enzyme regulation 1997;37():59-76.
1995: Stavit Drori; Gera D Eytan; Yehuda G Assaraf
Potentiation of anticancer-drug cytotoxicity by multidrug-resistance chemosensitizers involves alterations in membrane fluidity leading to increased membrane permeability.
European journal of biochemistry / FEBS 1995;228(3):1020-9.
1994: Yehuda G Assaraf; Stavit Drori; Uriel Bachrach; V Shaugan-Labay
Determination of multidrug resistance levels in cultured mammalian cells using ornithine decarboxylase activity.
Analytical biochemistry 1994;216(1):97-109.