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Stefan Dröse

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Publications

TOP 3
Stefan Dröse
Differential effects of complex II on mitochondrial ROS production and their relation to cardioprotective pre- and postconditioning.
Heinrich Heide; Ina Koch; Andreas S Reichert; Bettina Schwamb; Mirco Steger; Ilka Wittig; Martin Zörnig; Jörg Ackermann; Lea Bleier; Stefan Dröse; Ulrich Brandt
Complexome profiling identifies TMEM126B as a component of the mitochondrial complex I assembly complex.
Kristina Leuner; Sören Mai; Angelo Occhipinti; Richard D Palmiter; Andreas S Reichert; Carola Schiller; Tanja Schütt; Michael Willem; Ilka Wittig; Ulrich Brandt; Stefan Dröse; Gunter P Eckert; Schamim H Eckert; Christian Haass; Marina Jendrach; Shane E Kruse; Christopher Kurz; Walter E Müller
Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation.

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All Publications

2013: Stefan Dröse
Differential effects of complex II on mitochondrial ROS production and their relation to cardioprotective pre- and postconditioning.
Biochimica et biophysica acta 2013;1827(5):578-87.
2012: Heinrich Heide; Ina Koch; Andreas S Reichert; Bettina Schwamb; Mirco Steger; Ilka Wittig; Martin Zörnig; Jörg Ackermann; Lea Bleier; Stefan Dröse; Ulrich Brandt
Complexome profiling identifies TMEM126B as a component of the mitochondrial complex I assembly complex.
Cell metabolism 2012;16(4):538-49.
2012: Kristina Leuner; Sören Mai; Angelo Occhipinti; Richard D Palmiter; Andreas S Reichert; Carola Schiller; Tanja Schütt; Michael Willem; Ilka Wittig; Ulrich Brandt; Stefan Dröse; Gunter P Eckert; Schamim H Eckert; Christian Haass; Marina Jendrach; Shane E Kruse; Christopher Kurz; Walter E Müller
Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation.
Antioxidants & redox signaling 2012;16(12):1421-33.
2012: Stefan Dröse; Ulrich Brandt
Molecular mechanisms of superoxide production by the mitochondrial respiratory chain.
Advances in experimental medicine and biology 2012;748():145-69.
2011: Andrea Weil; Ilka Wittig; Ulrich Brandt; Stefan Dröse; Karin Luce; Heinz D Osiewacz
Unmasking a temperature-dependent effect of the P. anserina i-AAA protease on aging and development.
Cell cycle (Georgetown, Tex.) 2011;10(24):4280-90.
2011: Nils Hartmann; Claudia Lück; Matthias Platzer; Kathrin Reichwald; Michael Ristow; Sebastian Schmeisser; Eva Terzibasi; Ilka Wittig; Ulrich Brandt; Alessandro Cellerino; Stefan Dröse; Ulrike Gausmann; Michael Graf; Christin Hahn; Christoph Englert
Mitochondrial DNA copy number and function decrease with age in the short-lived fish Nothobranchius furzeri.
Aging cell 2011;10(5):824-31.
2011: Stefan Dröse; Heinrich Heide; Stefan Kerscher; Stephanie Krack; Nina Morgner; Esther Nübel; Michael Radermacher; Lucie Sokolova; Mirco Steger; Volker Zickermann; Klaus Zwicker; Hans-Dieter Barth; Bernhard Brutschy; Ulrich Brandt
Functional dissection of the proton pumping modules of mitochondrial complex I.
PLoS biology 2011;9(8):e1001128.
2011: Stefan Dröse; Lea Bleier; Ulrich Brandt
A common mechanism links differently acting complex II inhibitors to cardioprotection: modulation of mitochondrial reactive oxygen species production.
Molecular pharmacology 2011;79(5):814-22.
2010: Daniel Dikov; Angelique Aulbach; Britta Muster; Stefan Dröse; Marina Jendrach; Jürgen Bereiter-Hahn
Do UCP2 and mild uncoupling improve longevity?
Experimental gerontology 2010;45(7-8):586-95.
2010: Maja A Tocilescu; Uta Fendel; Klaus Zwicker; Stefan Dröse; Stefan Kerscher; Ulrich Brandt
The role of a conserved tyrosine in the 49-kDa subunit of complex I for ubiquinone binding and reduction.
Biochimica et biophysica acta 2010;1797(6-7):625-32.
2010: Dmitry Namgaladze; Stefan Preiss; Stefan Dröse; Ulrich Brandt; Bernhard Brüne
Phospholipase A2-modified low density lipoprotein induces mitochondrial uncoupling and lowers reactive oxygen species in phagocytes.
Atherosclerosis 2010;208(1):142-7.
2009: Virginie Rhein; Xiaomin Song; Andreas Wiesner; Lars M Ittner; Ginette Baysang; Fides Meier; Laurence Ozmen; Horst Bluethmann; Stefan Dröse; Ulrich Brandt; Egemen Savaskan; Christian Czech; Jürgen Götz; Anne Eckert
Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(47):20057-62.
2009: Susanne Hauptmann; Isabel Scherping; Stefan Dröse; Ulrich Brandt; K L Schulz; Marina Jendrach; Kristina Leuner; Anne Eckert; Walter E Müller
Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice.
Neurobiology of aging 2009;30(10):1574-86.
2009: Stefan Dröse; Peter J Hanley; Ulrich Brandt
Ambivalent effects of diazoxide on mitochondrial ROS production at respiratory chain complexes I and III.
Biochimica et biophysica acta 2009;1790(6):558-65.
2009: Judith Haendeler; Stefan Dröse; Nicole Büchner; Sascha Jakob; Joachim Altschmied; Christine Goy; Ioakim Spyridopoulos; Andreas M Zeiher; Ulrich Brandt; Stefanie Dimmeler
Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(6):929-35.
2009: Stefan Dröse; Alexander Galkin; Ulrich Brandt
Chapter 26 Measurement of superoxide formation by mitochondrial complex I of Yarrowia lipolytica.
Methods in enzymology 2009;456():475-90.
2008: Anne Eckert; Susanne Hauptmann; Isabel Scherping; Jessica Meinhardt; Virginie Rhein; Stefan Dröse; Ulrich Brandt; Marcus Fändrich; Walter E Müller; Jürgen Götz
Oligomeric and fibrillar species of beta-amyloid (A beta 42) both impair mitochondrial function in P301L tau transgenic mice.
Journal of molecular medicine (Berlin, Germany) 2008;86(11):1255-67.
2008: Volker Zickermann; Stefan Dröse; Maja A Tocilescu; Klaus Zwicker; Stefan Kerscher; Ulrich Brandt
Challenges in elucidating structure and mechanism of proton pumping NADH:ubiquinone oxidoreductase (complex I).
Journal of bioenergetics and biomembranes 2008;40(5):475-83.
2008: Stefan Dröse; Ulrich Brandt
The mechanism of mitochondrial superoxide production by the cytochrome bc1 complex.
The Journal of biological chemistry 2008;283(31):21649-54.
2008: Guo-Bin Hu; William J Rice; Stefan Dröse; Karlheinz Altendorf; David L Stokes
Three-dimensional structure of the KdpFABC complex of Escherichia coli by electron tomography of two-dimensional crystals.
Journal of structural biology 2008;161(3):411-8.
2008: Stefan Kerscher; Stefan Dröse; Volker Zickermann; Ulrich Brandt
The three families of respiratory NADH dehydrogenases.
Results and problems in cell differentiation 2008;45():185-222.
2007: B Herr; Jie Zhou; Stefan Dröse; Bernhard Brüne
The interaction of superoxide with nitric oxide destabilizes hypoxia-inducible factor-1alpha.
Cellular and molecular life sciences : CMLS 2007;64(24):3295-305.
2007: Mathias Soller; Stefan Dröse; Ulrich Brandt; Bernhard Brüne; Andreas von Knethen
Mechanism of thiazolidinedione-dependent cell death in Jurkat T cells.
Molecular pharmacology 2007;71(6):1535-44.
2007: Hans-Hermann Hoepken; Suzana Gispert; Blas Morales; Oliver Wingerter; Domenico Del Turco; Alexander Mülsch; Robert L Nussbaum; Klaus Müller; Stefan Dröse; Ulrich Brandt; Thomas Deller; Brunhilde Wirth; Alexei P Kudin; Wolfram S Kunz; Georg Auburger
Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6.
Neurobiology of disease 2007;25(2):401-11.
2006: Alexander Galkin; Stefan Dröse; Ulrich Brandt
The proton pumping stoichiometry of purified mitochondrial complex I reconstituted into proteoliposomes.
Biochimica et biophysica acta 2006;1757(12):1575-81.
2006: Stefan Dröse; Ulrich Brandt; Peter J Hanley
K+-independent actions of diazoxide question the role of inner membrane KATP channels in mitochondrial cytoprotective signaling.
The Journal of biological chemistry 2006;281(33):23733-9.
2006: Marina A Schwab; Sven W Sauer; Jürgen G Okun; Leo G J Nijtmans; Richard J T Rodenburg; Lambert P van den Heuvel; Stefan Dröse; Ulrich Brandt; Georg F Hoffmann; Henk ter Laak; Stefan Kölker; Jan A M Smeitink
Secondary mitochondrial dysfunction in propionic aciduria: a pathogenic role for endogenous mitochondrial toxins.
The Biochemical journal 2006;398(1):107-12.
2006: Klaus Zwicker; Alexander Galkin; Stefan Dröse; Ljuban Grgic; Stefan Kerscher; Ulrich Brandt
The Redox-Bohr group associated with iron-sulfur cluster N2 of complex I.
The Journal of biological chemistry 2006;281(32):23013-7.
2006: Romain A Duval; Guy Lewin; Eva Peris; Nadia Chahboune; Aurelio Garofano; Stefan Dröse; Diego Cortes; Ulrich Brandt; Reynald Hocquemiller
Heterocyclic analogues of squamocin as inhibitors of mitochondrial complex I. On the role of the terminal lactone of annonaceous acetogenins.
Biochemistry 2006;45(8):2721-8.
2005: Stefan Dröse; Alexander Galkin; Ulrich Brandt
Proton pumping by complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica reconstituted into proteoliposomes.
Biochimica et biophysica acta 2005;1710(2-3):87-95.
2005: Ulrich Brandt; Albina Abdrakhmanova; Volker Zickermann; Alexander Galkin; Stefan Dröse; Klaus Zwicker; Stefan Kerscher
Structure-function relationships in mitochondrial complex I of the strictly aerobic yeast Yarrowia lipolytica.
Biochemical Society transactions 2005;33(Pt 4):840-4.
2005: Della C David; Susanne Hauptmann; Isabel Scherping; Katrin Schuessel; Uta Keil; Patrizia Rizzu; Rivka Ravid; Stefan Dröse; Ulrich Brandt; Walter E Müller; Anne Eckert; Jürgen Götz
Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice.
The Journal of biological chemistry 2005;280(25):23802-14.
2005: Peter J Hanley; Stefan Dröse; Ulrich Brandt; Rachel A Lareau; Abir L Banerjee; DK Srivastava; Leonard J Banaszak; Joseph J Barycki; Paul P Van Veldhoven; Jürgen Daut
5-Hydroxydecanoate is metabolised in mitochondria and creates a rate-limiting bottleneck for beta-oxidation of fatty acids.
The Journal of physiology 2005;562(Pt 2):307-18.
2004: Alexandra Keller; Annisuddin Mohamed; Stefan Dröse; Ulrich Brandt; Ingrid Fleming; Ralf P Brandes
Analysis of dichlorodihydrofluorescein and dihydrocalcein as probes for the detection of intracellular reactive oxygen species.
Free radical research 2004;38(12):1257-67.
2003: Ulrich Brandt; Stefan Kerscher; Stefan Dröse; Klaus Zwicker; Volker Zickermann
Proton pumping by NADH:ubiquinone oxidoreductase. A redox driven conformational change mechanism?
FEBS letters 2003;545(1):9-17.
2002: Markus Huss; Gudrun Ingenhorst; Simone Koenig; Michael Gassel; Stefan Dröse; Axel Zeeck; Karlheinz Altendorf; Helmut Wieczorek
Concanamycin A, the specific inhibitor of V-ATPases, binds to the V(o) subunit c.
The Journal of biological chemistry 2002;277(43):40544-8.
2002: Stefan Dröse; Klaus Zwicker; Ulrich Brandt
Full recovery of the NADH:ubiquinone activity of complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica by the addition of phospholipids.
Biochimica et biophysica acta 2002;1556(1):65-72.
2002: Stefan Kerscher; Stefan Dröse; Klaus Zwicker; Volker Zickermann; Ulrich Brandt
Yarrowia lipolytica, a yeast genetic system to study mitochondrial complex I.
Biochimica et biophysica acta 2002;1555(1-3):83-91.
2001: Stefan Dröse; C Boddien; Michael Gassel; Gudrun Ingenhorst; Axel Zeeck; Karlheinz Altendorf
Semisynthetic derivatives of concanamycin A and C, as inhibitors of V- and P-type ATPases: structure-activity investigations and developments of photoaffinity probes.
Biochemistry 2001;40(9):2816-25.
2000: M Schrader; Klaus Fendler; Ernst Bamberg; Michael Gassel; Wolfgang Epstein; Karlheinz Altendorf; Stefan Dröse
Replacement of glycine 232 by aspartic acid in the KdpA subunit broadens the ion specificity of the K(+)-translocating KdpFABC complex.
Biophysical journal 2000;79(2):802-13.
1999: Klaus Fendler; Stefan Dröse; Wolfgang Epstein; Ernst Bamberg; Karlheinz Altendorf
The Kdp-ATPase of Escherichia coli mediates an ATP-dependent, K+-independent electrogenic partial reaction.
Biochemistry 1999;38(6):1850-6.
1998: Karlheinz Altendorf; Michael Gassel; W Puppe; T Möllenkamp; Axel Zeeck; C Boddien; Klaus Fendler; E Bamberg; Stefan Dröse
Structure and function of the Kdp-ATPase of Escherichia coli.
Acta physiologica Scandinavica. Supplementum 1998;643():137-46.
1997: Stefan Dröse; Karlheinz Altendorf
Bafilomycins and concanamycins as inhibitors of V-ATPases and P-ATPases.
The Journal of experimental biology 1997;200(Pt 1):1-8.
1996: Klaus Fendler; Stefan Dröse; Karlheinz Altendorf; Ernst Bamberg
Electrogenic K+ transport by the Kdp-ATPase of Escherichia coli.
Biochemistry 1996;35(24):8009-17.
1993: Stefan Dröse; K U Bindseil; Emma Jean Bowman; A Siebers; A Zeeck; Karlheinz Altendorf
Inhibitory effect of modified bafilomycins and concanamycins on P- and V-type adenosinetriphosphatases.
Biochemistry 1993;32(15):3902-6.