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Christian Drosten

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Florian Zirkel; Christian Drosten; Andreas Kurth; Hanna Roth; John Ziebuhr; Sandra Junglen
Identification and characterization of genetically divergent members of the newly established family mesoniviridae.
Stefanie Gierer; Adeline Heurich; Heike Hofmann; Franziska Kaup; Annika Krämer-Kühl; Benjamin Meyer; Graham Simmons; Thomas von Hahn; Kathrin Welsch; Michael Winkler; Florian Wrensch; Stephanie Bertram; Ulf Dittmer; Christian Drosten; Stefan Pöhlmann
The Spike Protein of the Emerging Betacoronavirus EMC Uses a Novel Coronavirus Receptor for Entry, Can Be Activated by TMPRSS2, and Is Targeted by Neutralizing Antibodies.
Sonia Etenna Lekana-Douki; Jan Felix Drexler; Christian Drosten; Mirdad Kazanji; Augustin Mouinga-Ondémé; Dieudonné Nkoghe; Eric M Leroy
Early introduction and delayed dissemination of pandemic influenza, Gabon.

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All Publications

2013: Florian Zirkel; Christian Drosten; Andreas Kurth; Hanna Roth; John Ziebuhr; Sandra Junglen
Identification and characterization of genetically divergent members of the newly established family mesoniviridae.
Journal of virology 2013;87(11):6346-58.
2013: Stefanie Gierer; Adeline Heurich; Heike Hofmann; Franziska Kaup; Annika Krämer-Kühl; Benjamin Meyer; Graham Simmons; Thomas von Hahn; Kathrin Welsch; Michael Winkler; Florian Wrensch; Stephanie Bertram; Ulf Dittmer; Christian Drosten; Stefan Pöhlmann
The Spike Protein of the Emerging Betacoronavirus EMC Uses a Novel Coronavirus Receptor for Entry, Can Be Activated by TMPRSS2, and Is Targeted by Neutralizing Antibodies.
Journal of virology 2013;87(10):5502-11.
2013: Sonia Etenna Lekana-Douki; Jan Felix Drexler; Christian Drosten; Mirdad Kazanji; Augustin Mouinga-Ondémé; Dieudonné Nkoghe; Eric M Leroy
Early introduction and delayed dissemination of pandemic influenza, Gabon.
Emerging infectious diseases 2013;19(4):644-7.
2013: V Stalin Raj; Peter J M Rottier; Saskia L Smits; Volker Thiel; Ali Zaki; Berend Jan Bosch; Dick H W Dekkers; Jeroen A A Demmers; Ronald Dijkman; Christian Drosten; Ron A M Fouchier; Huihui Mou; Marcel Alexander Müller; Doreen Muth; Albert D M E Osterhaus; Bart L Haagmans
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC.
Nature 2013;495(7440):251-4.
2013: Augustina Annan; Priscilla Anti; Ebenezer Kofi Badu; Heather J Baldwin; Victor Max Corman; Olivia Agbenyega; Christian Drosten; Florian Gloza-Rausch; Elena V Godlevska; Elisabeth K V Kalko; Stefan M Klose; Peter H C Lina; Benjamin Meyer; Evans Ewald Nkrumah; Samuel Oppong; Michael Owusu; Chantal Reusken; Yaw Adu Sarkodie; Antje Seebens; Marco Tschapka; Peter Vallo; Jan Felix Drexler
Human Betacoronavirus 2c EMC/2012-related Viruses in Bats, Ghana and Europe.
Emerging infectious diseases 2013;19(3):456-9.
2013: Anna Maria Eis-Hübinger; Angelika Helmer; Ulrike Reber; Stephan Buderus; Till Dresbach; Christian Drosten; Isabella Eckerle; Andreas Müller
Two cases of sepsis-like illness in infants caused by human parechovirus traced back to elder siblings with mild gastroenteritis and respiratory symptoms.
Journal of clinical microbiology 2013;51(2):715-8.
2013: V M Corman; Jan Felix Drexler; Christian Drosten; Isabella Eckerle; W K Roth; Anna Maria Eis-Hübinger
Zoonotic hepatitis E virus strains in German blood donors.
Vox sanguinis 2013;104(2):179-80.
2013: Vm Corman; S Becker; T Bleicker; S Brunink; Markus Eickmann; M Eschbach-Bludau; O Landt; M Matrosovich; Christian Drosten
Specific detection by real-time reverse-transcription PCR assays of a novel avian influenza A(H7N9) strain associated with human spillover infections in China.
Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin 2013;18(16):.
2013: Gael D Maganga; Delphine Verrier; Rodrigo M Zerbinati; Jan F Drexler; Christian Drosten; Eric M Leroy
Molecular typing of PPRV strains detected during an outbreak in sheep and goats in south-eastern Gabon in 2011.
Virology journal 2013;10():82.
2013: Udo Buchholz; S Buda; Christian Drosten; T Bauer-Balci; F Bonin; Gérard Krause; B Meyer; D Muth; Andreas Nitsche; A Sanewski; Lars Schaade; Brunhilde Schweiger; N Wevering; T Wolff; M A Müller; Walter Haas
Contact investigation of a case of human novel coronavirus infection treated in a German hospital, October-November 2012.
Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin 2013;18(8):.
2013: Eveline Kindler; Marcel Alexander Müller; Doreen Muth; Regulo Rodriguez; Ronald Dijkman; Christian Drosten; Ron A M Fouchier; Robert Geffers; Ole J Hamming; Rune Hartmann; Hulda R Jónsdóttir; Volker Thiel
Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential.
mBio 2013;4(1):e00611-12.
2013: Steven Deeks; Christian Drosten; Louis Picker; Kanta Subbarao; Joann Suzich
Roadblocks to translational challenges on viral pathogenesis.
Nature medicine 2013;19(1):30-4.
2012: Hans Henrik Gad; Beate M Kümmerer; Sylvie Paulous; Aileen E Plate; Essia Belarbi; Valérie Caro; Laure Diancourt; Christian Drosten; Philippe Desprès
The E2-E166K substitution restores Chikungunya virus growth in OAS3 expressing cells by acting on viral entry.
Virology 2012;434(1):27-37.
2012: Tanel Mahlakõiv; Markus Mordstein; Marcel Alexander Müller; Daniel Ritz; Marta L DeDiego; Christian Drosten; Luis Enjuanes; Peter Staeheli
Combined action of type I and type III interferon restricts initial replication of severe acute respiratory syndrome coronavirus in the lung but fails to inhibit systemic virus spread.
The Journal of general virology 2012;93(Pt 12):2601-5.
2012: Alexander Lukashev; Vadim I Reznik; Raphael Taty Taty; OE Trotsenko; Anatoly P Gmyl; Gilda Grard; Valeria O Kotova; Eric M Leroy; Elena N Amjaga; Jan Felix Drexler; Christian Drosten
Novel serotypes 105 and 116 are members of distinct subgroups of human enterovirus C.
The Journal of general virology 2012;93(Pt 11):2357-62.
2012: Marco Marklewitz; Christian Drosten; Florian Gloza-Rausch; Beate Mareike Kümmerer; Andreas Kurth; Sandra Junglen
First isolation of an Entomobirnavirus from free-living insects.
The Journal of general virology 2012;93(Pt 11):2431-5.
2012: Jan Felix Drexler; Christian Drosten; Fabian Ebach; Samuel Acquah; Julia Adlkofer; Yaw Adu-Sarkodie; Augustina Annan; Petra Herzog; Jürgen May; Doreen Muth; Marcus Panning; Ulrike Reber; Nimarko Sarpong; Egbert Tannich; Anna Maria Eis-Hübinger
Human parvovirus 4 in nasal and fecal specimens from children, Ghana.
Emerging infectious diseases 2012;18(10):1650-3.
2012: Jürgen May; Marcus Panning; Ulrike Reber; Nimarko Sarpong; Ohene Adjei; Jan Felix Drexler; Christian Drosten; Anna Maria Eis-Hübinger
Human parvovirus 4 viremia in young children, Ghana.
Emerging infectious diseases 2012;18(10):1690-2.
2012: Jan Felix Drexler; Alexander Adam; Yaw Adu-Sarkodie; Victor Max Corman; Veronika Cottontail; Adriana Fumie Tateno; Florian Gloza-Rausch; Elisabeth K V Kalko; Stefan M Klose; Eric M Leroy; Alexander Lukashev; Rodrigo Melim Zerbinati; Marcel Alexander Müller; Samuel K Oppong; Andreas Osterman; Andrea Rasche; Annika Seelen; Rainer G Ulrich; Christian Drosten
Bats worldwide carry hepatitis E virus-related viruses that form a putative novel genus within the family Hepeviridae.
Journal of virology 2012;86(17):9134-47.
2012: Beate Mareike Kümmerer; Janett Wieseler; Sabine Gläsker; Klaus Grywna; Christian Drosten
Construction of an infectious Chikungunya virus cDNA clone and stable insertion of mCherry reporter genes at two different sites.
The Journal of general virology 2012;93(Pt 9):1991-5.
2012: Chris Lauber; Kouichi Morita; Phan Thi Nga; Eric J Snijder; John Ziebuhr; Florian Zirkel; Christian Drosten; Sandra Junglen; Alexander E Gorbalenya
Mesoniviridae: a proposed new family in the order Nidovirales formed by a single species of mosquito-borne viruses.
Archives of virology 2012;157(8):1623-8.
2012: Luiz V F da Silva Filho; Marina Buarque de Almeida; Jan Felix Drexler; Christian Drosten; José Eduardo Levi; Adriana Fumie Tateno; Rodrigo Melim Zerbinati; Lucy Vilas Boas; Cláudio Sérgio Pannuti
The differential clinical impact of human coronavirus species in children with cystic fibrosis.
The Journal of infectious diseases 2012;206(3):384-8.
2012: Jan Felix Drexler; Anna Maria Eis-Hübinger; Ulrike Reber; Andrea Wuttkopf; Christian Drosten
Performance of the novel Qiagen artus QS-RGQ viral load assays compared to that of the Abbott RealTime system with genetically diversified HIV and hepatitis C Virus plasma specimens.
Journal of clinical microbiology 2012;50(6):2114-7.
2012: Alexander Lukashev; Monika Eschbach-Bludau; Sigrid Baumgarte; Ilya S Belalov; Jan Felix Drexler; Christian Drosten
Genetic variation and recombination in Aichi virus.
The Journal of general virology 2012;93(Pt 6):1226-35.
2012: Anna-Winona Struck; Susanne Pfefferle; Marco Axmann; Christian Drosten; Bernd Meyer
A hexapeptide of the receptor-binding domain of SARS corona virus spike protein blocks viral entry into host cells via the human receptor ACE2.
Antiviral research 2012;94(3):288-96.
2012: Andreas Stöcker; Angela Peixoto de Mattos; Patrícia Silva Almeida; Luciana Oliveira Araujo; Jefferson Ivan Corrêa; Christian Drosten; Eduardo Martins Netto; Diana Brasil Pedral-Sampaio; Hugo da Costa Ribeiro; Tereza Cristina Medrado Ribeiro; Breno Frederico de Carvalho Dominguez Souza; Jan Felix Drexler
Cosavirus infection in persons with and without gastroenteritis, Brazil.
Emerging infectious diseases 2012;18(4):656-9.
2012: Javier Carbajo-Lozoya; Christian Drosten; Stephan Kallies; Marcel Alexander Müller; Volker Thiel; Albrecht von Brunn
Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506.
Virus research 2012;165(1):112-7.
2012: Mehdi Bouraï; Patricia Cassonnet; Thérèse Couderc; Philippe Desprès; Christian Drosten; Hans Henrik Gad; Yves Jacob; Louis M Jones; Delphine Judith; Beate Mareike Kümmerer; Marc Lecuit; Vincent Lotteau; Marianne Lucas-Hourani; Lionel Tafforeau; Frédéric Tangy; Patrice André; Pierre-Olivier Vidalain
Mapping of Chikungunya virus interactions with host proteins identified nsP2 as a highly connected viral component.
Journal of virology 2012;86(6):3121-34.
2012: Marcel Alexander Müller; Doreen Muth; Albert D M E Osterhaus; V Stalin Raj; Saskia L Smits; Sabine Specht; Tasnim Suliman; Marco Tschapka; Robert Wollny; Ali M Zaki; Katrin Zimmermann; Isabella Eckerle; Ron A M Fouchier; Bart L Haagmans; Stephan Kallies; Benjamin Meyer; Theo M Bestebroer; Tabea Binger; Christian Drosten
Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines.
mBio 2012;3(6):.
2012: V M Corman; J F Drexler; B L Haagmans; Marcel Alexander Müller; A D Osterhaus; T Binger; T Bleicker; F Bonin; U Costabel; U Dittmer; M Eschbach-Bludau; P Kreher; O Landt; E Lattwein; B Meyer; A Nitsche; B Schweiger; J Timm; T Wolff; Christian Drosten
Assays for laboratory confirmation of novel human coronavirus (hCoV-EMC) infections.
Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin 2012;17(49):.
2012: V M Corman; J F Drexler; R M Fouchier; Marcel Alexander Müller; A D Osterhaus; M Ballhause; T Bleicker; Isabella Eckerle; M Eschbach-Bludau; R Gopal; O Landt; D Muth; S van Boheemen; A Zaki; M Zambon; T M Bestebroer; Christian Drosten
Detection of a novel human coronavirus by real-time reverse-transcription polymerase chain reaction.
Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin 2012;17(39):.
2012: Sabrina Weiss; Peter T Witkowski; Nathan D Wolfe; Brita Auste; Jan Felix Drexler; Christian Drosten; Jakob Fahr; Boris Klempa; Fabian H Leendertz; Jean-Vivien Mombouli; Kathrin Nowak; Natalie Weber; Detlev H Kruger
Hantavirus in bat, Sierra Leone.
Emerging infectious diseases 2012;18(1):159-61.
2011: Stephanie Bertram; Christian Drosten; Ilona Glowacka; Kerstin Gnirss; Yuxian He; Olaf Jahn; Hayley Lavender; Marcel Alexander Müller; Inga Nehlmeier; Daniela Niemeyer; Graham Simmons; Elizabeth J Soilleux; Imke Steffen; Stefan Pöhlmann
Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease.
Journal of virology 2011;85(24):13363-72.
2011: Annika Kühl; Marcel Alexander Müller; Vincent J Munster; Georg Behrens; Christian Drosten; Heinz Feldmann; Kerstin Gnirss; Georg Herrler; Markus Hoffmann; Miriam Kiene; Theodros Solomon Tsegaye; Stefan Pöhlmann
Comparative analysis of Ebola virus glycoprotein interactions with human and bat cells.
The Journal of infectious diseases 2011;204 Suppl 3():S840-9.
2011: Gael D Maganga; Ghislain Ebang Ella; Mathieu Bourgarel; Jan Felix Drexler; Christian Drosten; Jean-Paul Gonzalez; Eric M Leroy
Is Marburg virus enzootic in Gabon?
The Journal of infectious diseases 2011;204 Suppl 3():S800-3.
2011: Gilda Grard; Jan Felix Drexler; Christian Drosten; Joseph Fair; Jean-Jacques Muyembe; Nathan D Wolfe; Eric M Leroy
Re-emergence of Crimean-Congo hemorrhagic fever virus in Central Africa.
PLoS neglected tropical diseases 2011;5(10):e1350.
2011: M Marklewitz; Georg Pauli; Andreas Kurth; Fabian H Leendertz; A Lukashev; Christian Drosten; Heinz Ellerbrok; W Grasse; S Handrick; Sandra Junglen
Gouleako virus isolated from West African mosquitoes constitutes a proposed novel genus in the family Bunyaviridae.
Journal of virology 2011;85(17):9227-34.
2011: Ilona Glowacka; Stephanie Bertram; Marcel Alexander Müller; Paul Allen; Elizabeth Soilleux; Susanne Pfefferle; Imke Steffen; Theodros Solomon Tsegaye; Yuxian He; Kerstin Gnirss; Daniela Niemeyer; Heike Schneider; Christian Drosten; Stefan Pöhlmann
Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response.
Journal of virology 2011;85(9):4122-34.
2011: Jan Felix Drexler; Victor Max Corman; Tom Wegner; Adriana Fumie Tateno; Rodrigo Melim Zerbinati; Florian Gloza-Rausch; Antje Seebens; Marcel Alexander Müller; Christian Drosten
Amplification of emerging viruses in a bat colony.
Emerging infectious diseases 2011;17(3):449-56.
2011: Jan Felix Drexler; Klaus Grywna; Alexander Lukashev; Andreas Stöcker; Patrícia Silva Almeida; Janett Wieseler; Tereza Cristina Medrado Ribeiro; Nadine Petersen; Hugo da Costa Ribeiro; Ilya Belalov; Beate Mareike Kümmerer; Christian Drosten
Full genome sequence analysis of parechoviruses from Brazil reveals geographical patterns in the evolution of non-structural genes and intratypic recombination in the capsid region.
The Journal of general virology 2011;92(Pt 3):564-71.
2011: Marcus Panning; Sigrid Baumgarte; Thomas Laue; Sibylle Bierbaum; Sabine Raith; Jan Felix Drexler; Angelika Helmer; Valeria Falcone-Kapper; Georg Kochs; Hartmut Campe; Daniela Huzly; Anna Maria Eis-Hübinger; Christian Drosten
Singleplex real-time RT-PCR for detection of influenza A virus and simultaneous differentiation of A/H1N1v and evaluation of the RealStar influenza kit.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2011;50(2):171-4.
2011: Jan M Vetter; Lars Frisch; Christian Drosten; R Stefan Ross; Michael Roggendorf; Bernd Wolters; Thomas Müller; H Burkhard Dick; Norbert Pfeiffer
Survival after transplantation of corneas from a rabies-infected donor.
Cornea 2011;30(2):241-4.
2011: Susanne E Biesold; Victor M Corman; Jan Felix Drexler; Christian Drosten; Florian Gloza-Rausch; Elisabeth K V Kalko; Samuel Oppong; Daniel Ritz; Robert Wollny; Marcel Alexander Müller
Type I interferon reaction to viral infection in interferon-competent, immortalized cell lines from the African fruit bat Eidolon helvum.
PloS one 2011;6(11):e28131.
2011: Florian Zirkel; Thomas Briese; Christian Drosten; Heinz Ellerbrok; Andreas Kurth; Fabian H Leendertz; W Ian Lipkin; Georg Pauli; Phenix-Lan Quan; John Ziebuhr; Sandra Junglen
An insect nidovirus emerging from a primary tropical rainforest.
mBio 2011;2(3):e00077-11.
2010: Aroldo J B Carneiro; Carlos R Franke; Andreas Stocker; Flavia Dos Santos; Jose E Ungar de Sa; Evandro Moraes-Silva; Jose N M Alves; Sebastian Brunink; Victor M Corman; Christian Drosten; Jan Felix Drexler
Rabies virus RNA in naturally infected vampire bats, northeastern Brazil.
Emerging infectious diseases 2010;16(12):2004-6.
2010: Jan Felix Drexler; Florian Gloza-Rausch; Jörg Glende; Victor Max Corman; Doreen Muth; Matthias Goettsche; Antje Seebens; Matthias Niedrig; Susanne Pfefferle; Stoian Yordanov; Lyubomir Zhelyazkov; Uwe Hermanns; Peter Vallo; Alexander Lukashev; Marcel Alexander Müller; Hongkui Deng; Georg Herrler; Christian Drosten
Genomic characterization of severe acute respiratory syndrome-related coronavirus in European bats and classification of coronaviruses based on partial RNA-dependent RNA polymerase gene sequences.
Journal of virology 2010;84(21):11336-49.
2010: Chantal B E M Reusken; Peter H C Lina; Annemarie Pielaat; Ankje de Vries; Cecile Dam-Deisz; Jeroen Adema; Jan Felix Drexler; Christian Drosten; Engbert A Kooi
Circulation of group 2 coronaviruses in a bat species common to urban areas in Western Europe.
Vector borne and zoonotic diseases (Larchmont, N.Y.) 2010;10(8):785-91.
2010: Jürgen J Wenzel; Marcus Panning; Karen L Kaul; Kathy A Mangold; Paula A Revell; Ruth Ann Luna; Héctor Zepeda; Lizbeth Perea; Joel A Vazquez-Perez; Steve Young; Bojana Rodic-Polic; Markus Eickmann; Christian Drosten; Wolfgang Jilg; Udo Reischl
Analytical performance determination and clinical validation of the novel Roche RealTime Ready Influenza A/H1N1 Detection Set.
Journal of clinical microbiology 2010;48(9):3088-94.
2010: Yanchen Zhou; Kai Lu; Susanne Pfefferle; Stephanie Bertram; Ilona Glowacka; Christian Drosten; Stefan Pöhlmann; Graham Simmons
A single asparagine-linked glycosylation site of the severe acute respiratory syndrome coronavirus spike glycoprotein facilitates inhibition by mannose-binding lectin through multiple mechanisms.
Journal of virology 2010;84(17):8753-64.
2010: Klaus Grywna; Bernd Kupfer; Marcus Panning; Jan Felix Drexler; Petra Emmerich; Christian Drosten; Beate M Kümmerer
Detection of all species of the genus Alphavirus by reverse transcription-PCR with diagnostic sensitivity.
Journal of clinical microbiology 2010;48(9):3386-7.
2010: Marcus Panning; Sigrid Baumgarte; Susanne Pfefferle; Tanja Maier; Andreas Martens; Christian Drosten
Comparative analysis of rabies virus reverse transcription-PCR and virus isolation using samples from a patient infected with rabies virus.
Journal of clinical microbiology 2010;48(8):2960-2.
2010: Marcus Panning; Robin Kobbe; Silke Vollbach; Jan Felix Drexler; Samuel Adjei; Ohene Adjei; Christian Drosten; May Jürgen; Anna Maria Eis-Hubinger
Novel human parvovirus 4 genotype 3 in infants, Ghana.
Emerging infectious diseases 2010;16(7):1143-6.
2010: Marcus Panning; Petra Emmerich; Stephan Olschläger; Sergiusz Bojenko; Lamine Koivogui; Arthur Marx; Peter Clement Lugala; Stephan Günther; Daniel G Bausch; Christian Drosten
Laboratory diagnosis of Lassa fever, liberia.
Emerging infectious diseases 2010;16(6):1041-3.
2010: Nicole Fischer; Claudia Schulz; Kristin Stieler; Oliver Hohn; Christoph Lange; Christian Drosten; Martin Aepfelbacher
Xenotropic murine leukemia virus-related gammaretrovirus in respiratory tract.
Emerging infectious diseases 2010;16(6):1000-2.
2010: Stephan Olschläger; Michaela Lelke; Petra Emmerich; Marcus Panning; Christian Drosten; Meike Hass; Danny Asogun; Deborah Ehichioya; Sunday Omilabu; Stephan Günther
Improved detection of Lassa virus by reverse transcription-PCR targeting the 5' region of S RNA.
Journal of clinical microbiology 2010;48(6):2009-13.
2010: Markus Mordstein; Eva Neugebauer; Vanessa Ditt; Birthe Jessen; Toni Rieger; Valeria Falcone; Frederic Sorgeloos; Stephan Ehl; Daniel Mayer; Georg Kochs; Martin Schwemmle; Stephan Günther; Christian Drosten; Thomas Michiels; Peter Staeheli
Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections.
Journal of virology 2010;84(11):5670-7.
2010: Jan Felix Drexler; Sigrid Baumgarte; Luciano Kleber de Souza Luna; Andreas Stöcker; Patrícia Silva Almeida; Tereza Cristina Medrado Ribeiro; Nadine Petersen; Petra Herzog; Célia Pedroso; Carlos Brites; Hugo da Costa Ribeiro; Anatoly Gmyl; Christian Drosten; Alexander Lukashev
Genomic features and evolutionary constraints in Saffold-like cardioviruses.
The Journal of general virology 2010;91(Pt 6):1418-27.
2010: Anke Edelmann; Ulrich Kalus; Anke Oltmann; Angela Stein; Anett Unbehaun; Christian Drosten; Detlev H Krüger; Jörg Hofmann
Improvement of an ultrasensitive human immunodeficiency virus type 1 real-time reverse transcriptase-polymerase chain reaction targeting the long terminal repeat region.
Transfusion 2010;50(3):685-92.
2010: Saijo Thomas; Jagdish Rai; Lijo John; Stephan Günther; Christian Drosten; Brigitte M Pützer; Stephan Schaefer
Functional dissection of the alphavirus capsid protease: sequence requirements for activity.
Virology journal 2010;7():327.
2010: Anna Maria Eis-Hübinger; Jan Felix Drexler; Ulrike Reber; Marcus Panning; Christian Drosten; Marijke Weber-Schehl; Doris Hedges; Sally A Baylis; W Kurt Roth
Absence of detection of novel human parvoviruses in German plasma donations.
Transfusion 2010;50(1):266-7.
2010: Marcel Alexander Müller; Lia van der Hoek; Daniel Voss; Oliver Bader; Dörte Lehmann; Axel R Schulz; Stephan Kallies; Tasnim Suliman; Burtram Clintom Fielding; Christian Drosten; Matthias Niedrig
Human coronavirus NL63 open reading frame 3 encodes a virion-incorporated N-glycosylated membrane protein.
Virology journal 2010;7():6.
2010: Ilona Glowacka; Stephanie Bertram; Petra Herzog; Susanne Pfefferle; Imke Steffen; Marcus O Muench; Graham Simmons; Heike Hofmann; Thomas Kuri; Friedemann Weber; Jutta Eichler; Christian Drosten; Stefan Pöhlmann
Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63.
Journal of virology 2010;84(2):1198-205.
2009: Jan Felix Drexler; Angelika Helmer; Heike Kirberg; Ulrike Reber; Marcus Panning; Marcel Alexander Müller; Katja Höfling; Bertfried Matz; Christian Drosten; Anna Maria Eis-Hübinger
Poor clinical sensitivity of rapid antigen test for influenza A pandemic (H1N1) 2009 virus.
Emerging infectious diseases 2009;15(10):1662-4.
2009: Susanne Pfefferle; Samuel Oppong; Jan Felix Drexler; Florian Gloza-Rausch; Anne Ipsen; Antje Seebens; Marcel Alexander Müller; Augustina Annan; Peter Vallo; Yaw Adu-Sarkodie; Thomas F Kruppa; Christian Drosten
Distant relatives of severe acute respiratory syndrome coronavirus and close relatives of human coronavirus 229E in bats, Ghana.
Emerging infectious diseases 2009;15(9):1377-84.
2009: Marcus Panning; Markus Hess; Waldemar Fischer; Klaus Grywna; Martin Pfeffer; Christian Drosten
Performance of the RealStar Chikungunya virus real-time reverse transcription-PCR kit.
Journal of clinical microbiology 2009;47(9):3014-6.
2009: Matthias Niedrig; Hervé Zeller; Isabelle Schuffenecker; Christian Drosten; Petra Emmerich; L Rumer; Oliver Donoso Mantke
International diagnostic accuracy study for the serological detection of chikungunya virus infection.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2009;15(9):880-4.
2009: Marcus Panning; Dominic Wichmann; Klaus Grywna; Augustina Annan; Sriyal Wijesinghe; S A M Kularatne; Christian Drosten
No evidence of chikungunya virus and antibodies shortly before the outbreak on Sri Lanka.
Medical microbiology and immunology 2009;198(2):103-6.
2009: Roman Wölfel; Janusz T Paweska; Nadine Petersen; Antoinette A Grobbelaar; Patricia A Leman; Roger Hewson; Marie-Claude Georges-Courbot; Anna Papa; Volker Heiser; Marcus Panning; Stephan Günther; Christian Drosten
Low-density macroarray for rapid detection and identification of Crimean-Congo hemorrhagic fever virus.
Journal of clinical microbiology 2009;47(4):1025-30.
2009: M Kariuki Njenga; Janusz Paweska; Rose Wanjala; Carol Y Rao; Matthew Weiner; Victor Omballa; Elizabeth T Luman; David Mutonga; Shanaaz Sharif; Marcus Panning; Christian Drosten; Daniel R Feikin; Robert Breiman
Using a field quantitative real-time PCR test to rapidly identify highly viremic rift valley fever cases.
Journal of clinical microbiology 2009;47(4):1166-71.
2009: Marcus Panning; Remi CHARREL; Oliver Donoso Mantke; Oliver D Mantke; Olfert Landt; Matthias Niedrig; Christian Drosten
Coordinated implementation of chikungunya virus reverse transcription-PCR.
Emerging infectious diseases 2009;15(3):469-71.
2009: Stefanie Kramme; Le Van An; Nguyen Dinh Khoa; Le Van Trin; Egbert Tannich; Jan Rybniker; Bernhard Fleischer; Christian Drosten; Marcus Panning
Orientia tsutsugamushi bacteremia and cytokine levels in Vietnamese scrub typhus patients.
Journal of clinical microbiology 2009;47(3):586-9.
2009: Jan Felix Drexler; Bernd Kupfer; Nadine Petersen; Rejane Maria Tommasini Grotto; Silvia Maria Corvino Rodrigues; Klaus Grywna; Marcus Panning; Augustina Annan; Giovanni Faria Silva; Jill Douglas; Evelyn S C Koay; Heidi Smuts; Eduardo M Netto; Peter Simmonds; Maria Inês de Moura Campos Pardini; W Kurt Roth; Christian Drosten
A novel diagnostic target in the hepatitis C virus genome.
PLoS medicine 2009;6(2):e31.
2009: Jan Felix Drexler; Klaus Grywna; Andreas Stöcker; Patrícia Silva Almeida; Tereza Cristina Medrado-Ribeiro; Monika Eschbach-Bludau; Nadine Petersen; Hugo da Costa-Ribeiro-Jr; Christian Drosten
Novel human parechovirus from Brazil.
Emerging infectious diseases 2009;15(2):310-3.
2009: Susanne Pfefferle; Verena Krähling; Vanessa Ditt; Klaus Grywna; Elke Mühlberger; Christian Drosten
Reverse genetic characterization of the natural genomic deletion in SARS-Coronavirus strain Frankfurt-1 open reading frame 7b reveals an attenuating function of the 7b protein in-vitro and in-vivo.
Virology journal 2009;6():131.
2009: Jan Felix Drexler; Victor Max Corman; Florian Gloza-Rausch; Antje Seebens; Augustina Annan; Anne Ipsen; Thomas F Kruppa; Marcel Alexander Müller; Elisabeth K V Kalko; Yaw Adu-Sarkodie; Samuel Oppong; Christian Drosten
Henipavirus RNA in African bats.
PloS one 2009;4(7):e6367.
2009: Daniel Voss; Susanne Pfefferle; Christian Drosten; Lea Stevermann; Elisabetta Traggiai; Antonio Lanzavecchia; Stephan Becker
Studies on membrane topology, N-glycosylation and functionality of SARS-CoV membrane protein.
Virology journal 2009;6():79.
2009: Dominic Wichmann; Marcus Panning; Thomas Quack; Stefanie Kramme; Gerd-Dieter Burchard; Christoph Grevelding; Christian Drosten
Diagnosing schistosomiasis by detection of cell-free parasite DNA in human plasma.
PLoS neglected tropical diseases 2009;3(4):e422.
2008: Stefan Kowalzik; Nghia Vu Xuan; Benedikt Weissbrich; Barbara Scheiner; Tanja Schied; Christian Drosten; Andreas Müller; August Stich; Axel Rethwilm; Jochen Bodem
Characterisation of a chikungunya virus from a German patient returning from Mauritius and development of a serological test.
Medical microbiology and immunology 2008;197(4):381-6.
2008: Joerg Glende; Christel Schwegmann-Wessels; Marwan Al-Falah; Susanne Pfefferle; Xiuxia Qu; Hongkui Deng; Christian Drosten; Hassan Y Naim; Georg Herrler
Importance of cholesterol-rich membrane microdomains in the interaction of the S protein of SARS-coronavirus with the cellular receptor angiotensin-converting enzyme 2.
Virology 2008;381(2):215-21.
2008: Jan Felix Drexler; Luciano Kleber de Souza Luna; Andreas Stöcker; Patrícia Silva Almeida; Tereza Cristina Medrado Ribeiro; Nadine Petersen; Petra Herzog; Célia Pedroso; Hans-Iko Huppertz; Hugo da Costa Ribeiro; Sigrid Baumgarte; Christian Drosten
Circulation of 3 lineages of a novel Saffold cardiovirus in humans.
Emerging infectious diseases 2008;14(9):1398-405.
2008: Florian Gloza-Rausch; Anne Ipsen; Antje Seebens; Matthias Göttsche; Marcus Panning; Jan Felix Drexler; Nadine Petersen; Augustina Annan; Klaus Grywna; Marcel Alexander Müller; Susanne Pfefferle; Christian Drosten
Detection and prevalence patterns of group I coronaviruses in bats, northern Germany.
Emerging infectious diseases 2008;14(4):626-31.
2008: Nadine Litzba; Isabelle Schuffenecker; Hervé Zeller; Christian Drosten; Petra Emmerich; Remi CHARREL; Petra Kreher; Matthias Niedrig
Evaluation of the first commercial chikungunya virus indirect immunofluorescence test.
Journal of virological methods 2008;149(1):175-9.
2008: Marcus Panning; Klaus Grywna; Marjan Van Esbroeck; Petra Emmerich; Christian Drosten
Chikungunya fever in travelers returning to Europe from the Indian Ocean region, 2006.
Emerging infectious diseases 2008;14(3):416-22.
2008: Marcus Panning; Jochen Kilwinski; Susanne Greiner-Fischer; Martin Peters; Stefanie Kramme; Dimitrios Frangoulidis; Hermann Meyer; Klaus Henning; Christian Drosten
High throughput detection of Coxiella burnetii by real-time PCR with internal control system and automated DNA preparation.
BMC microbiology 2008;8():77.
2008: Luciano Kleber de Souza Luna; Sigrid Baumgarte; Klaus Grywna; Marcus Panning; Jan Felix Drexler; Christian Drosten
Identification of a contemporary human parechovirus type 1 by VIDISCA and characterisation of its full genome.
Virology journal 2008;5():26.
2008: Sigrid Baumgarte; Luciano Kleber de Souza Luna; Klaus Grywna; Marcus Panning; Jan Felix Drexler; Claudia Karsten; Hans-Iko Huppertz; Christian Drosten
Prevalence, types, and RNA concentrations of human parechoviruses, including a sixth parechovirus type, in stool samples from patients with acute enteritis.
Journal of clinical microbiology 2008;46(1):242-8.
2007: Simon Vieth; Christian Drosten; Oliver Lenz; Martin Vincent; Sunday Omilabu; Meike Hass; Beate Becker-Ziaja; Jan ter Meulen; Stuart T Nichol; Herbert Schmitz; Stephan Günther
RT-PCR assay for detection of Lassa virus and related Old World arenaviruses targeting the L gene.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2007;101(12):1253-64.
2007: Marcus Panning; Thomas Laue; Stephan Olschlager; Markus Eickmann; Stephan Becker; Sabine Raith; Marie-Claude Georges Courbot; Mikael Nilsson; Robin Gopal; Ake Lundkvist; Antonino di Caro; David Brown; Hermann Meyer; Graham Lloyd; Beate M Kummerer; Stephan Gunther; Christian Drosten
Diagnostic reverse-transcription polymerase chain reaction kit for filoviruses based on the strain collections of all European biosafety level 4 laboratories.
The Journal of infectious diseases 2007;196 Suppl 2():S199-204.
2007: Darja Duh; Ana Saksida; Miroslav Petrovec; Salih Ahmeti; Iusuf Dedushaj; Marcus Panning; Christian Drosten; Tatjana Avsic-Zupanc
Viral load as predictor of Crimean-Congo hemorrhagic fever outcome.
Emerging infectious diseases 2007;13(11):1769-72.
2007: Marcel Alexander Müller; Janusz T Paweska; Patricia A Leman; Christian Drosten; Klaus Grywna; Alan Kemp; L E O Braack; Karen Sonnenberg; Matthias Niedrig; Robert Swanepoel
Coronavirus antibodies in African bat species.
Emerging infectious diseases 2007;13(9):1367-70.
2007: Roman Wölfel; Janusz T Paweska; Nadine Petersen; Antoinette A Grobbelaar; Patricia A Leman; Roger Hewson; Marie-Claude Georges-Courbot; Anna Papa; Stephan Günther; Christian Drosten
Virus detection and monitoring of viral load in Crimean-Congo hemorrhagic fever virus patients.
Emerging infectious diseases 2007;13(7):1097-100.
2007: Winfried Taubitz; Jakob P Cramer; Anette Kapaun; Martin Pfeffer; Christian Drosten; Gerhard Dobler; Gerd D Burchard; Thomas Löscher
Chikungunya fever in travelers: clinical presentation and course.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007;45(1):e1-4.
2007: Anna Papa; Evangelia Papadimitriou; Luciano Kleber de Souza Luna; Motassim Al Masri; Efimia Souliou; Maria Eboriadou; Antonis Antoniadis; Christian Drosten
Coronaviruses in children, Greece.
Emerging infectious diseases 2007;13(6):947-9.
2007: Jan Felix Drexler; Luciano Kleber de Souza Luna; Celia Pedroso; Diana B Pedral-Sampaio; Artur T L Queiroz; Carlos Brites; Eduardo M Netto; Christian Drosten
Rates of and reasons for failure of commercial human immunodeficiency virus type 1 viral load assays in Brazil.
Journal of clinical microbiology 2007;45(6):2061-3.
2007: Anna Papa; Christian Drosten; Silva Bino; Evangelia Papadimitriou; Marcus Panning; Enkelejda Velo; Majlinda Kota; Arjan Harxhi; Antonis Antoniadis
Viral load and Crimean-Congo hemorrhagic fever.
Emerging infectious diseases 2007;13(5):805-6.
2007: S Schmiedel; Marcus Panning; A Lohse; K G Kreymann; C Gerloff; Gerd D Burchard; Christian Drosten
Case report on fatal human rabies infection in Hamburg, Germany, March 2007.
Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin 2007;12(5):E070531.5.
2007: Frauke Mattner; Cornelia Henke-Gendo; Andreas Martens; Christian Drosten; Thomas F Schulz; Albert Heim; Sebastian Suerbaum; Sabine Kuhn; Juliane Bruderek; Petra Gastmeier; Martin Strueber
Risk of rabies infection and adverse effects of postexposure prophylaxis in healthcare workers and other patient contacts exposed to a rabies virus-infected lung transplant recipient.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 2007;28(5):513-8.
2007: Luciano Kleber de Souza Luna; Marcus Panning; Klaus Grywna; Susanne Pfefferle; Christian Drosten
Spectrum of viruses and atypical bacteria in intercontinental air travelers with symptoms of acute respiratory infection.
The Journal of infectious diseases 2007;195(5):675-9.
2007: Luciano Kleber de Souza Luna; Volker Heiser; Nicolas Regamey; Marcus Panning; Jan Felix Drexler; Sabue Mulangu; Leo Poon; Sigrid Baumgarte; Bert Jan Haijema; Laurent Kaiser; Christian Drosten
Generic detection of coronaviruses and differentiation at the prototype strain level by reverse transcription-PCR and nonfluorescent low-density microarray.
Journal of clinical microbiology 2007;45(3):1049-52.
2007: Marcus Panning; Stefanie Kramme; Nadine Petersen; Christian Drosten
High throughput screening for spores and vegetative forms of pathogenic B. anthracis by an internally controlled real-time PCR assay with automated DNA preparation.
Medical microbiology and immunology 2007;196(1):41-50.
2006: Wolfgang Preiser; Jan Felix Drexler; Christian Drosten
HIV-1 viral load assays for resource-limited settings: clades matter.
PLoS medicine 2006;3(12):e538; author reply e550.
2006: Petra Emmerich; Corinna Thome-Bolduan; Christian Drosten; Stephan Gunther; Enikö Ban; Imke Sawinsky; Herbert Schmitz
Reverse ELISA for IgG and IgM antibodies to detect Lassa virus infections in Africa.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2006;37(4):277-81.
2006: Matthias Niedrig; Sonja Linke; Hervé Zeller; Christian Drosten
First international proficiency study on West Nile virus molecular detection.
Clinical chemistry 2006;52(10):1851-4.
2006: Christian Drosten; Marcus Panning; Jan Felix Drexler; Florian Hänsel; Celia Pedroso; Jane Yeats; Luciano Kleber de Souza Luna; Matthew Samuel; Britta Liedigk; Ute Lippert; Martin Stürmer; Hans Wilhelm Doerr; Carlos Brites; Wolfgang Preiser
Ultrasensitive monitoring of HIV-1 viral load by a low-cost real-time reverse transcription-PCR assay with internal control for the 5' long terminal repeat domain.
Clinical chemistry 2006;52(7):1258-66.
2006: Pierre Formenty; Eric M Leroy; Alain Epelboin; François Libama; Marco Lenzi; Hinrich Sudeck; Philippe Yaba; Yokouidé Allarangar; Paul Boumandouki; Virginot Blad Nkounkou; Christian Drosten; Allen Grolla; Heinz Feldmann; Cathy Roth
Detection of Ebola virus in oral fluid specimens during outbreaks of Ebola virus hemorrhagic fever in the Republic of Congo.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;42(11):1521-6.
2006: Gustavo Palacios; Thomas Briese; Vishal Kapoor; Omar Jabado; Zhiqiang Liu; Marietjie Venter; Junhui Zhai; Neil Renwick; Allen Grolla; Thomas W Geisbert; Christian Drosten; Jonathan S Towner; Jingyue Ju; Janusz T Paweska; Stuart T Nichol; Robert Swanepoel; Heinz Feldmann; Peter B Jahrling; W Ian Lipkin
MassTag polymerase chain reaction for differential diagnosis of viral hemorrhagic fever.
Emerging infectious diseases 2006;12(4):692-5.
2006: Matthias Niedrig; Hermann Meyer; Marcus Panning; Christian Drosten
Follow-up on diagnostic proficiency of laboratories equipped to perform orthopoxvirus detection and quantification by PCR: the second international external quality assurance study.
Journal of clinical microbiology 2006;44(4):1283-7.
2006: Elke Scandella; Klara K Eriksson; Tobias Hertzig; Christian Drosten; Lili Chen; Chunshan Gui; Xiaomin Luo; Jianhua Shen; Xu Shen; Stuart G Siddell; Burkhard Ludewig; Hualiang Jiang; Stephan Günther; Volker Thiel
Identification and evaluation of coronavirus replicase inhibitors using a replicon cell line.
Advances in experimental medicine and biology 2006;581():609-13.
2005: Sunday Aremu Omilabu; Sikiru Olanrewaju Badaru; Peter Okokhere; Danny Asogun; Christian Drosten; Petra Emmerich; Beate Becker-Ziaja; Herbert Schmitz; Stephan Günther
Lassa fever, Nigeria, 2003 and 2004.
Emerging infectious diseases 2005;11(10):1642-4.
2005: Hi-Gung BAe; Christian Drosten; Petra Emmerich; Robert Colebunders; Philippe Hantson; Stefan Pest; Muriel Parent; Herbert Schmitz; Marc-Aurel Warnat; Matthias Niedrig
Analysis of two imported cases of yellow fever infection from Ivory Coast and The Gambia to Germany and Belgium.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2005;33(4):274-80.
2005: Lili Chen; Chunshan Gui; Xiaomin Luo; Qingang Yang; Stephan Günther; Elke Scandella; Christian Drosten; Donglu Bai; Xichang He; Burkhard Ludewig; Jing Chen; Haibin Luo; Yiming Yang; Yifu Yang; Jianping Zou; Volker Thiel; Kaixian Chen; Jianhua Shen; Xu Shen; Hualiang Jiang
Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro.
Journal of virology 2005;79(11):7095-103.
2005: Christian Drosten; Ewald Müller-Kunert; Manfred Dietrich; Johannes Gerdes; Herbert Schmitz
Topographic and quantitative display of integrated human immunodeficiency virus-1 provirus DNA in human lymph nodes by real-time polymerase chain reaction.
The Journal of molecular diagnostics : JMD 2005;7(2):219-25.
2005: Simon Vieth; Christian Drosten; Remi CHARREL; Heinz Feldmann; Stephan Günther
Establishment of conventional and fluorescence resonance energy transfer-based real-time PCR assays for detection of pathogenic New World arenaviruses.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2005;32(3):229-35.
2005: Jianjun Liu; Siew Lan Lim; Yijun Ruan; Ai Ee Ling; Lisa F P Ng; Christian Drosten; Edison Liu; Lawrence W Stanton; Martin L Hibberd
SARS transmission pattern in Singapore reassessed by viral sequence variation analysis.
PLoS medicine 2005;2(2):e43.
2004: Christian Drosten; Hans Wilhelm Doerr; Wilina Lim; Klaus Stöhr; Matthias Niedrig
SARS molecular detection external quality assurance.
Emerging infectious diseases 2004;10(12):2200-3.
2004: Stefanie Kramme; Gisela Bretzel; Marcus Panning; Joseph Kawuma; Christian Drosten
Detection and quantification of Mycobacterium leprae in tissue samples by real-time PCR.
Medical microbiology and immunology 2004;193(4):189-93.
2004: Stephan Günther; Marcel Asper; Christina Röser; Luciano Kleber de Souza Luna; Christian Drosten; Beate Becker-Ziaja; Peter Borowski; Huan-Ming Chen; Ramachandra S Hosmane
Application of real-time PCR for testing antiviral compounds against Lassa virus, SARS coronavirus and Ebola virus in vitro.
Antiviral research 2004;63(3):209-15.
2004: Tsanan Giroglou; Jindrich Cinatl; Holger Rabenau; Christian Drosten; Harald Schwalbe; Hans Wilhelm Doerr; Dorothee von Laer
Retroviral vectors pseudotyped with severe acute respiratory syndrome coronavirus S protein.
Journal of virology 2004;78(17):9007-15.
2004: Karin Lemmer; Oliver Donoso Mantke; Hi-Gung BAe; Jan Groen; Christian Drosten; Matthias Niedrig
External quality control assessment in PCR diagnostics of dengue virus infections.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2004;30(4):291-6.
2004: Nathalie Charlier; Richard Molenkamp; Pieter Leyssen; Jan Paeshuyse; Christian Drosten; Marcus Panning; Erik De Clercq; Peter J Bredenbeek; Johan Neyts
Exchanging the yellow fever virus envelope proteins with Modoc virus prM and E proteins results in a chimeric virus that is neuroinvasive in SCID mice.
Journal of virology 2004;78(14):7418-26.
2004: Christian Drosten; Lily-Lily Chiu; Marcus Panning; Hoe Nam Leong; Wolfgang Preiser; John S Tam; Stephan Günther; Stefanie Kramme; Petra Emmerich; Wooi Loon Ng; Herbert Schmitz; Evelyn S C Koay
Evaluation of advanced reverse transcription-PCR assays and an alternative PCR target region for detection of severe acute respiratory syndrome-associated coronavirus.
Journal of clinical microbiology 2004;42(5):2043-7.
2004: Victoria A Olson; Thomas Laue; Miriam T Laker; Igor V Babkin; Christian Drosten; Sergei N Shchelkunov; Matthias Niedrig; Inger K Damon; Hermann Meyer
Real-time PCR system for detection of orthopoxviruses and simultaneous identification of smallpox virus.
Journal of clinical microbiology 2004;42(5):1940-6.
2004: Matthias Niedrig; Herbert Schmitz; Stephan Becker; Stephan Günther; Jan ter Meulen; Herman Meyer; Heinz Ellerbrok; Andreas Nitsche; Hans R Gelderblom; Christian Drosten
First international quality assurance study on the rapid detection of viral agents of bioterrorism.
Journal of clinical microbiology 2004;42(4):1753-5.
2004: Michael Schmidt; Veronika Brixner; Brigitte Ruster; Michael K Hourfar; Christian Drosten; Wolfgang Preiser; Erhard Seifried; W Kurt Roth
NAT screening of blood donors for severe acute respiratory syndrome coronavirus can potentially prevent transfusion associated transmissions.
Transfusion 2004;44(4):470-5.
2004: Marcus Panning; Marcel Asper; Stefanie Kramme; Herbert Schmitz; Christian Drosten
Rapid detection and differentiation of human pathogenic orthopox viruses by a fluorescence resonance energy transfer real-time PCR assay.
Clinical chemistry 2004;50(4):702-8.
2004: Marcel Asper; Thomas Sternsdorf; Meike Hass; Christian Drosten; Antje Rhode; Herbert Schmitz; Stephan Günther
Inhibition of different Lassa virus strains by alpha and gamma interferons and comparison with a less pathogenic arenavirus.
Journal of virology 2004;78(6):3162-9.
2004: Christian Drosten; Thomas Nippraschk; Christoph Manegold; Helga Meisel; Veronika Brixner; W Kurt Roth; Anani Apedjinou; Stephan Günther
Prevalence of hepatitis B virus DNA in anti-HBc-positive/HBsAg-negative sera correlates with HCV but not HIV serostatus.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2004;29(1):59-68.
2004: Annemarie Berger; Christian Drosten; Hans Wilhelm Doerr; Martin Stürmer; Wolfgang Preiser
Severe acute respiratory syndrome (SARS)--paradigm of an emerging viral infection.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2004;29(1):13-22.
2003: Christian Drosten; Marcus Panning; Stefanie Kramme
Detection of Mycobacterium tuberculosis by real-time PCR using pan-mycobacterial primers and a pair of fluorescence resonance energy transfer probes specific for the M. tuberculosis complex.
Clinical chemistry 2003;49(10):1659-61.
2003: Christian Drosten; Wolfgang Preiser; Stephan Günther; Herbert Schmitz; Hans Wilhelm Doerr
Severe acute respiratory syndrome: identification of the etiological agent.
Trends in molecular medicine 2003;9(8):325-7.
2003: Thijs Kuiken; Ron A M Fouchier; Martin Schutten; Guus F Rimmelzwaan; Geert van Amerongen; Debby van Riel; Jon D Laman; Ton de Jong; G J J van Doornum; Wilina Lim; Ai Ee Ling; Paul K S Chan; John S Tam; Maria C Zambon; Robin Gopal; Christian Drosten; Sylvie van der Werf; Nicolas Escriou; Jean-Claude Manuguerra; Klaus Stöhr; J S M Peiris; Albert D M E Osterhaus
Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome.
Lancet 2003;362(9380):263-70.
2003: August Stich; Stephan Günther; Christian Drosten; Petra Emmerich; Dominic E Dwyer; Linda Hueston; Wolfgang Hetzel; Armin Kirschner; Klaus Fleischer
Clinical and laboratory findings on the first imported case of Murray Valley encephalitis in Europe.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;37(2):e19-21.
2003: Sebastian E B Graefe; B S Meyer; Bertram Müller-Myhsok; Franz Rüschendorf; Christian Drosten; Thomas Laue; Christiane Steeg; P Nürnberg; Bernhard Fleischer
Murine susceptibility to Chagas' disease maps to chromosomes 5 and 17.
Genes and immunity 2003;4(5):321-5.
2003: Volker Rickerts; Timo Wolf; Carsten Rottmann; Wolfgang Preiser; Christian Drosten; V Jakobi; H N Leong; Hans-Reinhard Brodt
[Clinical presentation and management of the severe acute respiratory syndrome (SARS)].
Deutsche medizinische Wochenschrift (1946) 2003;128(20):1109-14.
2003: Walter H Haas; Thomas Breuer; Günter Pfaff; Herbert Schmitz; Päivi Köhler; Marcel Asper; Petra Emmerich; Christian Drosten; Uta Gölnitz; Klaus Fleischer; Stephan Günther
Imported Lassa fever in Germany: surveillance and management of contact persons.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;36(10):1254-8.
2003: Christian Drosten; Stephan Günther; Wolfgang Preiser; Sylvie van der Werf; Hans-Reinhard Brodt; Stephan Becker; Holger Rabenau; Marcus Panning; Larissa Kolesnikova; Ron A M Fouchier; Annemarie Berger; Ana-Maria Burguière; Jindrich Cinatl; Markus Eickmann; Nicolas Escriou; Klaus Grywna; Stefanie Kramme; Jean-Claude Manuguerra; Stefanie Müller; Volker Rickerts; Martin Stürmer; Simon Vieth; Hans-Dieter Klenk; Albert D M E Osterhaus; Herbert Schmitz; Hans Wilhelm Doerr
Identification of a novel coronavirus in patients with severe acute respiratory syndrome.
The New England journal of medicine 2003;348(20):1967-76.
2003: Alexandra Schulz; Katja Mellenthin; Gabriele Schönian; Bernhard Fleischer; Christian Drosten
Detection, differentiation, and quantitation of pathogenic leishmania organisms by a fluorescence resonance energy transfer-based real-time PCR assay.
Journal of clinical microbiology 2003;41(4):1529-35.
2003: Pieter Leyssen; Jan Paeshuyse; Nathalie Charlier; Alfons Van Lommel; Christian Drosten; Erik De Clercq; Johan Neyts
Impact of direct virus-induced neuronal dysfunction and immunological damage on the progression of flavivirus (Modoc) encephalitis in a murine model.
Journal of neurovirology 2003;9(1):69-78.
2003: Pieter Leyssen; Christian Drosten; Marcus Paning; Nathalie Charlier; Jan Paeshuyse; Erik De Clercq; Johan Neyts
Interferons, interferon inducers, and interferon-ribavirin in treatment of flavivirus-induced encephalitis in mice.
Antimicrobial agents and chemotherapy 2003;47(2):777-82.
2003: Christian Drosten; Beate M Kümmerer; Herbert Schmitz; Stephan Günther
Molecular diagnostics of viral hemorrhagic fevers.
Antiviral research 2003;57(1-2):61-87.
2002: Christian Drosten; Marcus Panning; Stephan Guenther; Herbert Schmitz
False-negative results of PCR assay with plasma of patients with severe viral hemorrhagic fever.
Journal of clinical microbiology 2002;40(11):4394-5.
2002: Nathalie Charlier; Pieter Leyssen; Jan Paeshuyse; Christian Drosten; Herbert Schmitz; Alfons Van Lommel; Erik De Clercq; Johan Neyts
Infection of SCID mice with Montana Myotis leukoencephalitis virus as a model for flavivirus encephalitis.
The Journal of general virology 2002;83(Pt 8):1887-96.
2002: W Kurt Roth; Marijke Weber; Detlev Petersen; Christian Drosten; Sylvia Buhr; Walid Sireis; Wolfgang Weichert; Doris Hedges; Erhard Seifried
NAT for HBV and anti-HBc testing increase blood safety.
Transfusion 2002;42(7):869-75.
2002: W Kurt Roth; Marijke Weber; Sylvia Buhr; Christian Drosten; Wolfgang Weichert; Walid Sireis; Doris Hedges; Erhard Seifried
Yield of HCV and HIV-1 NAT after screening of 3.6 million blood donations in central Europe.
Transfusion 2002;42(7):862-8.
2002: Christian Drosten; Stephan Göttig; Stefan Schilling; Marcel Asper; Marcus Panning; Herbert Schmitz; Stephan Günther
Rapid detection and quantification of RNA of Ebola and Marburg viruses, Lassa virus, Crimean-Congo hemorrhagic fever virus, Rift Valley fever virus, dengue virus, and yellow fever virus by real-time reverse transcription-PCR.
Journal of clinical microbiology 2002;40(7):2323-30.
2002: Simon Vieth; Christoph Manegold; Christian Drosten; Thomas Nippraschk; Stephan Günther
Sequence and phylogenetic analysis of hepatitis B virus genotype G isolated in Germany.
Virus genes 2002;24(2):153-6.
2002: Christian Drosten; Dirk Minnak; Petra Emmerich; Herbert Schmitz; Thomas Reinicke
Crimean-Congo hemorrhagic fever in Kosovo.
Journal of clinical microbiology 2002;40(3):1122-3.
2002: Herbert Schmitz; Bernhard Köhler; Thomas Laue; Christian Drosten; Peter J Veldkamp; Stephan Günther; Petra Emmerich; Hans P Geisen; Klaus Fleischer; Matthias F C Beersma; Achim Hoerauf
Monitoring of clinical and laboratory data in two cases of imported Lassa fever.
Microbes and infection / Institut Pasteur 2002;4(1):43-50.
2001: Christian Drosten; Erhard Seifried; W Kurt Roth
TaqMan 5'-nuclease human immunodeficiency virus type 1 PCR assay with phage-packaged competitive internal control for high-throughput blood donor screening.
Journal of clinical microbiology 2001;39(12):4302-8.
2001: Stephan Günther; B Weisner; A Roth; T Grewing; Marcel Asper; Christian Drosten; Petra Emmerich; J Petersen; M Wilczek; Herbert Schmitz
Lassa fever encephalopathy: Lassa virus in cerebrospinal fluid but not in serum.
The Journal of infectious diseases 2001;184(3):345-9.
2001: Pieter Leyssen; Christian Drosten; H Schmitz; Johan Neyts
A novel model for the study of the therapy of flavivirus infections using the Modoc virus.
Virology 2001;279(1):27-37.
2000: Christian Drosten; Marijke Weber; Erhard Seifried; W Kurt Roth
Evaluation of a new PCR assay with competitive internal control sequence for blood donor screening.
Transfusion 2000;40(6):718-24.
2000: W Kurt Roth; Sylvia Buhr; Christian Drosten; Erhard Seifried
NAT and viral safety in blood transfusion.
Vox sanguinis 2000;78 Suppl 2():257-9.