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Jacques Drouin
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16
Nemer, Mona
15
Gauthier, Yves
9
Lanctôt, Christian
9
Tremblay, Jacques
9
Vallette-Kasic, Sophie
8
Pulichino, Anne-Marie
8
Maira, Mario
7
Bilodeau, Steve
6
Brue, Thierry
6
Jeannotte, Lucie
6
Couture, Catherine
5
Chamberland, Michel
5
Charron, Jean
5
Lamolet, Bruno
4
Marcil, Alexandre
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All Publications
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2009: Bilodeau Steve; Roussel-Gervais Audrey; Drouin Jacques
Distinct developmental roles of cell cycle inhibitors p57Kip2 and p27Kip1 distinguish pituitary progenitor cell cycle exit from cell cycle reentry of differentiated cells.
Molecular and cellular biology 2009;29(7):1895-908.
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2008: Langlais David; Couture Catherine; Balsalobre Aurélio; Drouin Jacques
Regulatory network analyses reveal genome-wide potentiation of LIF signaling by glucocorticoids and define an innate cell defense response.
PLoS genetics 2008;4(10):e1000224.
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2008: Lavoie Pierre-Luc; Budry Lionel; Balsalobre Aurélio; Drouin Jacques
Developmental dependence on NurRE and EboxNeuro for expression of pituitary proopiomelanocortin.
Molecular endocrinology (Baltimore, Md.) 2008;22(7):1647-57.
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2007: Coulon Vincent; L'Honoré Aurore; Ouimette Jean-François; Dumontier Emilie; van den Munckhof Pepijn; Drouin Jacques
A muscle-specific promoter directs Pitx3 gene expression in skeletal muscle cells.
The Journal of biological chemistry 2007;282(45):33192-200.
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2007: Vallette-Kasic Sophie; Couture Catherine; Balsalobre Aurelio; Gauthier Yves; Metherell Louise; Dattani Mehul; Drouin Jacques
The TPIT gene mutation M86R associated with isolated adrenocorticotropin deficiency interferes with protein: protein interactions.
The Journal of clinical endocrinology and metabolism 2007;92(10):3991-9.
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2007: Drouin J; Bilodeau S; Vallette S
Of old and new diseases: genetics of pituitary ACTH excess (Cushing) and deficiency.
Clinical genetics 2007;72(3):175-82.
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2007: L'Honoré Aurore; Coulon Vincent; Marcil Alexandre; Lebel Mélanie; Lafrance-Vanasse Julien; Gage Philip; Camper Sally; Drouin Jacques
Sequential expression and redundancy of Pitx2 and Pitx3 genes during muscle development.
Developmental biology 2007;307(2):421-33.
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2006: Bilodeau Steve; Vallette-Kasic Sophie; Gauthier Yves; Figarella-Branger Dominique; Brue Thierry; Berthelet France; Lacroix André; Batista Dalia; Stratakis Constantine; Hanson Jeanette; Meij Björn; Drouin Jacques
Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease.
Genes & development 2006;20(20):2871-86.
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2006: Weintrob Naomi; Drouin Jacques; Vallette-Kasic Sophie; Taub Ellen; Marom Daphna; Lebenthal Yael; Klinger Gil; Bron-Harlev Efrat; Shohat Mordechai
Low estriol levels in the maternal triple-marker screen as a predictor of isolated adrenocorticotropic hormone deficiency caused by a new mutation in the TPIT gene.
Pediatrics 2006;117(2):e322-7.
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2006: van den Munckhof Pepijn; Gilbert François; Chamberland Michel; Lévesque Daniel; Drouin Jacques
Striatal neuroadaptation and rescue of locomotor deficit by L-dopa in aphakia mice, a model of Parkinson's disease.
Journal of neurochemistry 2006;96(1):160-70.
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2006: Drouin Jacques
Molecular mechanisms of pituitary differentiation and regulation: implications for hormone deficiencies and hormone resistance syndromes.
Frontiers of hormone research 2006;35():74-87.
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2005: Batsché Eric; Desroches Julien; Bilodeau Steve; Gauthier Yves; Drouin Jacques
Rb enhances p160/SRC coactivator-dependent activity of nuclear receptors and hormone responsiveness.
The Journal of biological chemistry 2005;280(20):19746-56.
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2005: Nudi Maria; Ouimette Jean-François; Drouin Jacques
Bone morphogenic protein (Smad)-mediated repression of proopiomelanocortin transcription by interference with Pitx/Tpit activity.
Molecular endocrinology (Baltimore, Md.) 2005;19(5):1329-42.
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2005: Batsché Eric; Moschopoulos Pandelis; Desroches Julien; Bilodeau Steve; Drouin Jacques
Retinoblastoma and the related pocket protein p107 act as coactivators of NeuroD1 to enhance gene transcription.
The Journal of biological chemistry 2005;280(16):16088-95.
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2005: Martens Christine; Bilodeau Steve; Maira Mario; Gauthier Yves; Drouin Jacques
Protein-protein interactions and transcriptional antagonism between the subfamily of NGFI-B/Nur77 orphan nuclear receptors and glucocorticoid receptor.
Molecular endocrinology (Baltimore, Md.) 2005;19(4):885-97.
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2004: Vallette-Kasic S; Pulichino A M; Gueydan M; Barlier A; David M; Malpuech G; Deal C; Van Vliet G; de Vroede M; Riepe F; Partsch C J; Sippell W; Berberoglu M; Atasay B; de Zegher F; Kyllo J; Donohoue P; Dechelotte P; Fassnacht M; Noordam K; Dunkel L; Pigeon B; Weill J; Yigit S; Brauner R; Leger J; Heinrich J J; Enjalbert A; Brue T; Drouin J
A neonatal form of isolated ACTH deficiency frequently associated with Tpit gene mutations.
Endocrine research 2004;30(4):943-4.
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2004: Pulichino Anne-Marie; Lamolet Bruno; Vallette-Kasic Sophie; Poulin Gino; Chu Khoi; Gillemot François; Tsai Ming-Jer; Drouin Jacques
Tpit-/-NeuroD1-/- mice reveal novel aspects of corticotroph development.
Endocrine research 2004;30(4):551-2.
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2004: Pulichino Anne-Marie; Vallette-Kasic Sophie; Couture Catherine; Brue Thierry; Drouin Jacques
[Tpit mutations reveal a new model of pituitary differentiation and account for isolated ACTH deficiency]
Médecine sciences : M/S 2004;20(11):1009-13.
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2004: Lamolet Bruno; Poulin Gino; Chu Khoi; Guillemot François; Tsai Ming-Jer; Drouin Jacques
Tpit-independent function of NeuroD1(BETA2) in pituitary corticotroph differentiation.
Molecular endocrinology (Baltimore, Md.) 2004;18(4):995-1003.
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2003: Maira Mario; Couture Catherine; Le Martelot Gwendal; Pulichino Anne-Marie; Bilodeau Steve; Drouin Jacques
The T-box factor Tpit recruits SRC/p160 co-activators and mediates hormone action.
The Journal of biological chemistry 2003;278(47):46523-32.
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2003: Goodyer Cynthia G; Tremblay Jacques J; Paradis François W; Marcil Alexandre; Lanctôt Christian; Gauthier Yves; Drouin Jacques
Pitx1 in vivo promoter activity and mechanisms of positive autoregulation.
Neuroendocrinology 2003;78(3):129-37.
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2003: Vallette-Kasic Sophie; Figarella-Branger Dominique; Grino Michel; Pulichino Anne-Marie; Dufour Henry; Grisoli François; Enjalbert Alain; Drouin Jacques; Brue Thierry
Differential regulation of proopiomelanocortin and pituitary-restricted transcription factor (TPIT), a new marker of normal and adenomatous human corticotrophs.
The Journal of clinical endocrinology and metabolism 2003;88(7):3050-6.
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2003: van den Munckhof Pepijn; Luk Kelvin C; Ste-Marie Line; Montgomery Jane; Blanchet Pierre J; Sadikot Abbas F; Drouin Jacques
Pitx3 is required for motor activity and for survival of a subset of midbrain dopaminergic neurons.
Development (Cambridge, England) 2003;130(11):2535-42.
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2003: Pulichino Anne-Marie; Vallette-Kasic Sophie; Tsai Judy Peih-Ying; Couture Catherine; Gauthier Yves; Drouin Jacques
Tpit determines alternate fates during pituitary cell differentiation.
Genes & development 2003;17(6):738-47.
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2003: Pulichino Anne-Marie; Vallette-Kasic Sophie; Couture Catherine; Gauthier Yves; Brue Thierry; David Michel; Malpuech Georges; Deal Cheri; Van Vliet Guy; De Vroede Monique; Riepe Felix G; Partsch Carl-Joachim; Sippell Wolfgang G; Berberoglu Merih; Atasay Begüm; Drouin Jacques
Human and mouse TPIT gene mutations cause early onset pituitary ACTH deficiency.
Genes & development 2003;17(6):711-6.
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2003: Maira Mario; Martens Christine; Batsché Eric; Gauthier Yves; Drouin Jacques
Dimer-specific potentiation of NGFI-B (Nur77) transcriptional activity by the protein kinase A pathway and AF-1-dependent coactivator recruitment.
Molecular and cellular biology 2003;23(3):763-76.
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2003: Marcil Alexandre; Dumontier Emilie; Chamberland Michel; Camper Sally A; Drouin Jacques
Pitx1 and Pitx2 are required for development of hindlimb buds.
Development (Cambridge, England) 2003;130(1):45-55.
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2001: Lebel M; Gauthier Y; Moreau A; Drouin J
Pitx3 activates mouse tyrosine hydroxylase promoter via a high-affinity binding site.
Journal of neurochemistry 2001;77(2):558-67.
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2001: Steff A M; Trop S; Maira M; Drouin J; Hugo P
Opposite ability of pre-TCR and alpha beta TCR to induce apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(8):5044-50.
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2001: Lamolet B; Pulichino A M; Lamonerie T; Gauthier Y; Brue T; Enjalbert A; Drouin J
A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins.
Cell 2001;104(6):849-59.
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2000: Poulin G; Lebel M; Chamberland M; Paradis F W; Drouin J
Specific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx family.
Molecular and cellular biology 2000;20(13):4826-37.
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2000: Tremblay J J; Goodyer C G; Drouin J
Transcriptional properties of Ptx1 and Ptx2 isoforms.
Neuroendocrinology 2000;71(5):277-86.
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1999: Maira M; Martens C; Philips A; Drouin J
Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation.
Molecular and cellular biology 1999;19(11):7549-57.
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1999: Tremblay J J; Marcil A; Gauthier Y; Drouin J
Ptx1 regulates SF-1 activity by an interaction that mimics the role of the ligand-binding domain.
The EMBO journal 1999;18(12):3431-41.
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1999: Lanctôt C; Moreau A; Chamberland M; Tremblay M L; Drouin J
Hindlimb patterning and mandible development require the Ptx1 gene.
Development (Cambridge, England) 1999;126(9):1805-10.
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1999: Tremblay J J; Drouin J
Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone beta gene transcription.
Molecular and cellular biology 1999;19(4):2567-76.
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1999: Elchebly M; Wagner J; Kennedy T E; Lanctôt C; Michaliszyn E; Itié A; Drouin J; Tremblay M L
Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase sigma.
Nature genetics 1999;21(3):330-3.
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1999: Lanctôt C; Gauthier Y; Drouin J
Pituitary homeobox 1 (Ptx1) is differentially expressed during pituitary development.
Endocrinology 1999;140(3):1416-22.
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1998: Drouin J; Lamolet B; Lamonerie T; Lanctôt C; Tremblay J J
The PTX family of homeodomain transcription factors during pituitary developments.
Molecular and cellular endocrinology 1998;140(1-2):31-6.
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1998: Drouin J; Maira M; Philips A
Novel mechanism of action for Nur77 and antagonism by glucocorticoids: a convergent mechanism for CRH activation and glucocorticoid repression of POMC gene transcription.
The Journal of steroid biochemistry and molecular biology 1998;65(1-6):59-63.
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1998: Acampora D; Mazan S; Tuorto F; Avantaggiato V; Tremblay J J; Lazzaro D; di Carlo A; Mariano A; Macchia P E; Corte G; Macchia V; Drouin J; Brûlet P; Simeone A
Transient dwarfism and hypogonadism in mice lacking Otx1 reveal prepubescent stage-specific control of pituitary levels of GH, FSH and LH.
Development (Cambridge, England) 1998;125(7):1229-39.
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1998: Tremblay J J; Lanctôt C; Drouin J
The pan-pituitary activator of transcription, Ptx1 (pituitary homeobox 1), acts in synergy with SF-1 and Pit1 and is an upstream regulator of the Lim-homeodomain gene Lim3/Lhx3.
Molecular endocrinology (Baltimore, Md.) 1998;12(3):428-41.
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1997: Poulin G; Turgeon B; Drouin J
NeuroD1/beta2 contributes to cell-specific transcription of the proopiomelanocortin gene.
Molecular and cellular biology 1997;17(11):6673-82.
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1997: Philips A; Maira M; Mullick A; Chamberland M; Lesage S; Hugo P; Drouin J
Antagonism between Nur77 and glucocorticoid receptor for control of transcription.
Molecular and cellular biology 1997;17(10):5952-9.
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1997: Philips A; Lesage S; Gingras R; Maira M H; Gauthier Y; Hugo P; Drouin J
Novel dimeric Nur77 signaling mechanism in endocrine and lymphoid cells.
Molecular and cellular biology 1997;17(10):5946-51.
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1997: Lanctôt C; Lamolet B; Drouin J
The bicoid-related homeoprotein Ptx1 defines the most anterior domain of the embryo and differentiates posterior from anterior lateral mesoderm.
Development (Cambridge, England) 1997;124(14):2807-17.
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1997: Crawford M J; Lanctôt C; Tremblay J J; Jenkins N; Gilbert D; Copeland N; Beatty B; Drouin J
Human and murine PTX1/Ptx1 gene maps to the region for Treacher Collins syndrome.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(11):841-5.
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1996: Lamonerie T; Tremblay J J; Lanctôt C; Therrien M; Gauthier Y; Drouin J
Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene.
Genes & development 1996;10(10):1284-95.
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1994: Argentin S; Ardati A; Tremblay S; Lihrmann I; Robitaille L; Drouin J; Nemer M
Developmental stage-specific regulation of atrial natriuretic factor gene transcription in cardiac cells.
Molecular and cellular biology 1994;14(1):777-90.
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1993: Therrien M; Drouin J
Molecular determinants for cell specificity and glucocorticoid repression of the proopiomelanocortin gene.
Annals of the New York Academy of Sciences 1993;680():663-71.
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1993: Therrien M; Drouin J
Cell-specific helix-loop-helix factor required for pituitary expression of the pro-opiomelanocortin gene.
Molecular and cellular biology 1993;13(4):2342-53.
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1993: Drouin J; Sun Y L; Chamberland M; Gauthier Y; De Léan A; Nemer M; Schmidt T J
Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene.
The EMBO journal 1993;12(1):145-56.
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1992: Drouin J; Sun Y L; Tremblay S; Lavender P; Schmidt T J; de Léan A; Nemer M
Homodimer formation is rate-limiting for high affinity DNA binding by glucocorticoid receptor.
Molecular endocrinology (Baltimore, Md.) 1992;6(8):1299-309.
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1991: Argentin S; Sun Y L; Lihrmann I; Schmidt T J; Drouin J; Nemer M
Distal cis-acting promoter sequences mediate glucocorticoid stimulation of cardiac atrial natriuretic factor gene transcription.
The Journal of biological chemistry 1991;266(34):23315-22.
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1991: Dagnino L; Drouin J; Nemer M
Differential expression of natriuretic peptide genes in cardiac and extracardiac tissues.
Molecular endocrinology (Baltimore, Md.) 1991;5(9):1292-300.
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1989: Drouin J; Trifiro M A; Plante R K; Nemer M; Eriksson P; Wrange O
Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription.
Molecular and cellular biology 1989;9(12):5305-14.
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1989: Charron J; Richard-Foy H; Berard D S; Hager G L; Drouin J
Independent glucocorticoid induction and repression of two contiguous responsive genes.
Molecular and cellular biology 1989;9(7):3127-31.
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1989: Drouin J; Nemer M; Charron J; Gagner J P; Jeannotte L; Sun Y L; Therrien M; Tremblay Y
Tissue-specific activity of the pro-opiomelanocortin (POMC) gene and repression by glucocorticoids.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1989;31(2):510-9.
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1989: Drouin J; Sun Y L; Nemer M
Glucocorticoid repression of pro-opiomelanocortin gene transcription.
Journal of steroid biochemistry 1989;34(1-6):63-9.
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1988: Tremblay Y; Tretjakoff I; Peterson A; Antakly T; Zhang C X; Drouin J
Pituitary-specific expression and glucocorticoid regulation of a proopiomelanocortin fusion gene in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(23):8890-4.
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1988: Nemer M; Antakly T; Argentin S; Lavigne J P; Drouin J
Cloning and expression of the atrial natriuretic factor gene.
Clinical physiology and biochemistry 1988;6(3-4):163-70.
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1987: Drouin J; Charron J; Gagner J P; Jeannotte L; Nemer M; Plante R K; Wrange O
Pro-opiomelanocortin gene: a model for negative regulation of transcription by glucocorticoids.
Journal of cellular biochemistry 1987;35(4):293-304.
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1987: Jeannotte L; Trifiro M A; Plante R K; Chamberland M; Drouin J
Tissue-specific activity of the pro-opiomelanocortin gene promoter.
Molecular and cellular biology 1987;7(11):4058-64.
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1987: Jeannotte L; Burbach J P; Drouin J
Unusual proopiomelanocortin ribonucleic acids in extrapituitary tissues: intronless transcripts in testes and long poly(A) tails in hypothalamus.
Molecular endocrinology (Baltimore, Md.) 1987;1(10):749-57.
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1987: Gagner J P; Drouin J
Tissue-specific regulation of pituitary proopiomelanocortin gene transcription by corticotropin-releasing hormone, 3',5'-cyclic adenosine monophosphate, and glucocorticoids.
Molecular endocrinology (Baltimore, Md.) 1987;1(10):677-82.
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1986: Charron J; Drouin J
Glucocorticoid inhibition of transcription from episomal proopiomelanocortin gene promoter.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(23):8903-7.
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1986: Nemer M; Sirois D; Drouin J
TaqI polymorphism at the 3' end of the human pronatriodilatin gene (hPND).
Nucleic acids research 1986;14(21):8697.
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1986: Nemer M; Sirois D; Drouin J
XhoI polymorphism at the human pronatriodilatin (hPND) gene locus.
Nucleic acids research 1986;14(21):8696.
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1985: Drouin J; Chamberland M; Charron J; Jeannotte L; Nemer M
Structure of the rat pro-opiomelanocortin (POMC) gene.
FEBS letters 1985;193(1):54-8.
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1985: Gagner J P; Drouin J
Opposite regulation of pro-opiomelanocortin gene transcription by glucocorticoids and CRH.
Molecular and cellular endocrinology 1985;40(1):25-32.
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1985: Argentin S; Nemer M; Drouin J; Scott G K; Kennedy B P; Davies P L
The gene for rat atrial natriuretic factor.
The Journal of biological chemistry 1985;260(8):4568-71.
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1984: Nemer M; Chamberland M; Sirois D; Argentin S; Drouin J; Dixon R A; Zivin R A; Condra J H
Gene structure of human cardiac hormone precursor, pronatriodilatin.
Nature 1984;312(5995):654-6.
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1984: Zivin R A; Condra J H; Dixon R A; Seidah N G; Chrétien M; Nemer M; Chamberland M; Drouin J
Molecular cloning and characterization of DNA sequences encoding rat and human atrial natriuretic factors.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(20):6325-9.
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1983: Boileau G; Barbeau C; Jeannotte L; Chrétien M; Drouin J
Complete structure of the porcine pro-opiomelanocortin mRNA derived from the nucleotide sequence of cloned cDNA.
Nucleic acids research 1983;11(22):8063-71.
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