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David Drubin

Research Profile

Living Beings

Saccharomyces cerevisiae

Chemicals & Drugs

Physiology

Anatomy

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Microscopy, Fluorescence

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Publications

TOP 3
Stefano Bertuzzi; David G Drubin
No shortcuts for research assessment.
Christopher Buser; David G Drubin
Ultrastructural imaging of endocytic sites in Saccharomyces cerevisiae by transmission electron microscopy and immunolabeling.
Alphée Michelot; Voytek Okreglak; Charles Boone; Michael Costanzo; Alexandre Grassart; David G Drubin
Actin filament elongation in Arp2/3-derived networks is controlled by three distinct mechanisms.

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All Publications

2013: Stefano Bertuzzi; David G Drubin
No shortcuts for research assessment.
Molecular biology of the cell 2013;24(10):1505-6.
2013: Christopher Buser; David G Drubin
Ultrastructural imaging of endocytic sites in Saccharomyces cerevisiae by transmission electron microscopy and immunolabeling.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2013;19(2):381-92.
2013: Alphée Michelot; Voytek Okreglak; Charles Boone; Michael Costanzo; Alexandre Grassart; David G Drubin
Actin filament elongation in Arp2/3-derived networks is controlled by three distinct mechanisms.
Developmental cell 2013;24(2):182-95.
2013: Matthias Spiess; Barbara Winsor; Johan-Owen de Craene; David G Drubin; Aline Huber; Alphée Michelot; Bruno RINALDI; Sylvie Friant
Lsb1 is a negative regulator of las17 dependent actin polymerization involved in endocytosis.
PloS one 2013;8(4):e61147.
2013: Xiaofeng Xin; Xinping Yang; Yingnan Zhang; Adenrele Akintobi; Charles Boone; Dryden Bouamalay; Aaron T Cheng; Jackie Cheng; Bridget Currell; David G Drubin; David Gfeller; Barth D Grant; Mark L Grimes; Ailan Guo; Tong Hao; David E Hill; Jingjing Li; Lianet Lopez; Adrien Lugari; Alevtina Pavlenco; Jean-François Rual; Kourosh Salehi-Ashtiani; Somasekar Seshagiri; Yun A Shen; Sachdev S Sidhu; Lin Sun; Raffi Tonikian; Marc Vidal; Gary D Bader
SH3 interactome conserves general function over specific form.
Molecular systems biology 2013;9():652.
2012: Yidi Sun; David G Drubin
The functions of anionic phospholipids during clathrin-mediated endocytosis site initiation and vesicle formation.
Journal of cell science 2012;125(Pt 24):6157-65.
2012: Jackie Cheng; Alexandre Grassart; David G Drubin
Myosin 1E coordinates actin assembly and cargo trafficking during clathrin-mediated endocytosis.
Molecular biology of the cell 2012;23(15):2891-904.
2012: Yidi Sun; Hiromu Takematsu; Yukari Yamane; Chao Zhang; Yasunori Kozutsumi; Yansong Miao; Kevan M Shokat; David G Drubin
Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathways.
Molecular biology of the cell 2012;23(12):2388-98.
2012: David G Drubin; Douglas R Kellogg
English as the universal language of science: opportunities and challenges.
Molecular biology of the cell 2012;23(8):1399.
2012: Yidi Sun; David G Drubin
Pik1-ing clathrin adaptors.
Nature cell biology 2012;14(3):231-2.
2012: Susheela Y Carroll; Helen E M Stimpson; Yidi Sun; Christopher P Toret; Jasper Weinberg; David G Drubin
Analysis of yeast endocytic site formation and maturation through a regulatory transition point.
Molecular biology of the cell 2012;23(4):657-68.
2012: Mojca Mattiazzi; Toni Petan; Yidi Sun; Heimo Wolinski; Gregor Anderluh; Andrej Bavdek; David G Drubin; Sepp D Kohlwein; Igor Križaj; Uroš Petrovič
A neurotoxic phospholipase A2 impairs yeast amphiphysin activity and reduces endocytosis.
PloS one 2012;7(7):e40931.
2012: Jeffrey B Woodruff; David G Drubin; Georjana Barnes
Spindle assembly requires complete disassembly of spindle remnants from the previous cell cycle.
Molecular biology of the cell 2012;23(2):258-67.
2011: Douglas R Kellogg; David G Drubin
MBoC 2011: same values, improved feng shui.
Molecular biology of the cell 2011;22(21):3917-8.
2011: Takuma Kishimoto; Jian Liu; Alphée Michelot; Yidi Sun; Christopher Buser; David G Drubin
Determinants of endocytic membrane geometry, stability, and scission.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(44):E979-88.
2011: Yutian Peng; Ali S Sarkeshik; Randall G Tyers; Catherine C L Wong; John Yates; David G Drubin; Yuko Nakajima; Georjana Barnes
Overlapping kinetochore targets of CK2 and Aurora B kinases in mitotic regulation.
Molecular biology of the cell 2011;22(15):2680-9.
2011: Alphée Michelot; David G Drubin
Building distinct actin filament networks in a common cytoplasm.
Current biology : CB 2011;21(14):R560-9.
2011: Yuko Nakajima; Yutian Peng; Adrianne Pigula; Randall G Tyers; Anthony Cormier; David G Drubin; Georjana Barnes
Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC-spindle interaction to ensure proper microtubule dynamics.
The Journal of cell biology 2011;194(1):137-53.
2011: Maho Uchida; Yidi Sun; Gerry McDermott; Christian Knoechel; Mark A Le Gros; Dilworth Parkinson; David G Drubin; Carolyn A Larabell
Quantitative analysis of yeast internal architecture using soft X-ray tomography.
Yeast (Chichester, England) 2011;28(3):227-36.
2011: David G Drubin
Any jackass can trash a manuscript, but it takes good scholarship to create one (how MBoC promotes civil and constructive peer review).
Molecular biology of the cell 2011;22(5):525-7.
2011: Jeffrey B Doyon; Bryan Zeitler; Jackie Cheng; Aaron T Cheng; Jennifer M Cherone; Yolanda Santiago; Andrew H Lee; Thuy D Vo; Yannick Doyon; Jeffrey C Miller; David E Paschon; Lei Zhang; Edward J Rebar; Philip D Gregory; Fyodor D Urnov; David G Drubin
Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells.
Nature cell biology 2011;13(3):331-7.
2011: Anita T Layton; Natasha S Savage; Audrey S Howell; Susheela Y Carroll; David G Drubin; Daniel J Lew
Modeling vesicle traffic reveals unexpected consequences for Cdc42p-mediated polarity establishment.
Current biology : CB 2011;21(3):184-94.
2010: Jeffrey B Woodruff; David G Drubin; Georjana Barnes
Mitotic spindle disassembly occurs via distinct subprocesses driven by the anaphase-promoting complex, Aurora B kinase, and kinesin-8.
The Journal of cell biology 2010;191(4):795-808.
2010: Douglas R Kellogg; David G Drubin
The 50th anniversary of the ASCB: celebrating by looking forward.
Molecular biology of the cell 2010;21(22):3761.
2010: Alphée Michelot; Michael Costanzo; Ali Sarkeshik; Charles Boone; John R Yates; David G Drubin
Reconstitution and protein composition analysis of endocytic actin patches.
Current biology : CB 2010;20(21):1890-9.
2010: David G Drubin; George Oster
Experimentalist meets theoretician: a tale of two scientific cultures.
Molecular biology of the cell 2010;21(13):2099-101.
2010: Voytek Okreglak; David G Drubin
Loss of Aip1 reveals a role in maintaining the actin monomer pool and an in vivo oligomer assembly pathway.
The Journal of cell biology 2010;188(6):769-77.
2010: Jian Liu; Yidi Sun; George F Oster; David G Drubin
Mechanochemical crosstalk during endocytic vesicle formation.
Current opinion in cell biology 2010;22(1):36-43.
2010: David G Drubin
Are you being served?
Molecular biology of the cell 2010;21(1):1-3.
2010: Brian A Young; Christopher Buser; David G Drubin
Isolation and partial purification of the Saccharomyces cerevisiae cytokinetic apparatus.
Cytoskeleton (Hoboken, N.J.) 2010;67(1):13-22.
2009: Junko Y Toshima; Jun-ichi Nakanishi; Kensaku Mizuno; Jiro Toshima; David G Drubin
Requirements for recruitment of a G protein-coupled receptor to clathrin-coated pits in budding yeast.
Molecular biology of the cell 2009;20(24):5039-50.
2009: Helen E M Stimpson; Christopher P Toret; Aaron T Cheng; Barbara S Pauly; David G Drubin
Early-arriving Syp1p and Ede1p function in endocytic site placement and formation in budding yeast.
Molecular biology of the cell 2009;20(22):4640-51.
2009: Susheela Y Carroll; Peter C Stirling; Helen E M Stimpson; Esther Giesselmann; Manfred J Schmitt; David G Drubin
A yeast killer toxin screen provides insights into a/b toxin entry, trafficking, and killing mechanisms.
Developmental cell 2009;17(4):552-60.
2009: Raffi Tonikian; Xiaofeng Xin; Christopher P Toret; David Gfeller; Christiane Landgraf; Simona Panni; Serena Paoluzi; Luisa Castagnoli; Bridget Currell; Somasekar Seshagiri; Haiyuan Yu; Barbara Winsor; Marc Vidal; Mark B Gerstein; Gary D Bader; Rudolf Volkmer; Gianni Cesareni; David G Drubin; Philip M Kim; Sachdev S Sidhu; Charles Boone
Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins.
PLoS biology 2009;7(10):e1000218.
2009: Jian Liu; Yidi Sun; David G Drubin; George F Oster
The mechanochemistry of endocytosis.
PLoS biology 2009;7(9):e1000204.
2009: Jeffrey B Woodruff; David G Drubin; Georjana Barnes
Dynein-driven mitotic spindle positioning restricted to anaphase by She1p inhibition of dynactin recruitment.
Molecular biology of the cell 2009;20(13):3003-11.
2009: Yuko Nakajima; Randall G Tyers; Catherine C L Wong; John R Yates; David G Drubin; Georjana Barnes
Nbl1p: a Borealin/Dasra/CSC-1-like protein essential for Aurora/Ipl1 complex function and integrity in Saccharomyces cerevisiae.
Molecular biology of the cell 2009;20(6):1772-84.
2008: Hong-Wei Wang; Sydney Long; Claudio Ciferri; Stefan Westermann; David G Drubin; Georjana Barnes; Eva Nogales
Architecture and flexibility of the yeast Ndc80 kinetochore complex.
Journal of molecular biology 2008;383(4):894-903.
2008: Christopher P Toret; Linda A Lee; Mariko Sekiya-Kawasaki; David G Drubin
Multiple pathways regulate endocytic coat disassembly in Saccharomyces cerevisiae for optimal downstream trafficking.
Traffic (Copenhagen, Denmark) 2008;9(5):848-59.
2007: Barbara S Pauly; David G Drubin
Clathrin: an amazing multifunctional dreamcoat?
Cell host & microbe 2007;2(5):288-90.
2007: Jonathan Wong; Yuko Nakajima; Stefan Westermann; Ching Shang; Jung-Seog Kang; Crystal Goodner; Pantea Houshmand; Stanley Fields; Clarence S M Chan; David G Drubin; Georjana Barnes; Tony R Hazbun
A protein interaction map of the mitotic spindle.
Molecular biology of the cell 2007;18(10):3800-9.
2007: Voytek Okreglak; David G Drubin
Cofilin recruitment and function during actin-mediated endocytosis dictated by actin nucleotide state.
The Journal of cell biology 2007;178(7):1251-64.
2007: Hong-Wei Wang; Vincent H Ramey; Stefan Westermann; Andres E Leschziner; Julie P I Welburn; Yuko Nakajima; David G Drubin; Georjana Barnes; Eva Nogales
Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven assembly and force-coupling mechanisms.
Nature structural & molecular biology 2007;14(8):721-6.
2007: Sarah L Barker; Linda A Lee; B Daniel Pierce; Lymarie Maldonado-Báez; David G Drubin; Beverly Wendland
Interaction of the endocytic scaffold protein Pan1 with the type I myosins contributes to the late stages of endocytosis.
Molecular biology of the cell 2007;18(8):2893-903.
2007: Sarah V Bradley; Teresa S Hyun; Katherine I Oravecz-Wilson; Lina Li; Erik I Waldorff; Alexander N Ermilov; Steven A Goldstein; Claire X Zhang; David G Drubin; Kate Varela; Albert F Parlow; Andrzej Dlugosz; Theodora S Ross
Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1.
Human molecular genetics 2007;16(11):1279-92.
2007: Yidi Sun; Susheela Carroll; Marko Kaksonen; Junko Toshima; David G Drubin
PtdIns(4,5)P2 turnover is required for multiple stages during clathrin- and actin-dependent endocytic internalization.
The Journal of cell biology 2007;177(2):355-67.
2007: Christophe Le Clainche; Barbara S Pauly; Claire X Zhang; Asa E Y Engqvist-Goldstein; Kimberley Cunningham; David G Drubin
A Hip1R-cortactin complex negatively regulates actin assembly associated with endocytosis.
The EMBO journal 2007;26(5):1199-210.
2007: Jiro Toshima; Junko Toshima; Mara C Duncan; M Jamie T V Cope; Yidi Sun; Adam C. Martin; Scott Anderson; John R Yates; Kensaku Mizuno; David G Drubin
Negative regulation of yeast Eps15-like Arp2/3 complex activator, Pan1p, by the Hip1R-related protein, Sla2p, during endocytosis.
Molecular biology of the cell 2007;18(2):658-68.
2007: Stefan Westermann; David G Drubin; Georjana Barnes
Structures and functions of yeast kinetochore complexes.
Annual review of biochemistry 2007;76():563-91.
2006: Christopher P Toret; David G Drubin
The budding yeast endocytic pathway.
Journal of cell science 2006;119(Pt 22):4585-7.
2006: Marko Kaksonen; David G Drubin
PALM reading: Seeing the future of cell biology at higher resolution.
Developmental cell 2006;11(4):438-9.
2006: Adam C. Martin; Matt D Welch; David G Drubin
Arp2/3 ATP hydrolysis-catalysed branch dissociation is critical for endocytic force generation.
Nature cell biology 2006;8(8):826-33.
2006: Jian Liu; Marko Kaksonen; David G Drubin; George Oster
Endocytic vesicle scission by lipid phase boundary forces.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(27):10277-82.
2006: Yidi Sun; Adam C. Martin; David G Drubin
Endocytic internalization in budding yeast requires coordinated actin nucleation and myosin motor activity.
Developmental cell 2006;11(1):33-46.
2006: Marko Kaksonen; Christopher P Toret; David G Drubin
Harnessing actin dynamics for clathrin-mediated endocytosis.
Nature reviews. Molecular cell biology 2006;7(6):404-14.
2006: Junko Toshima; Jiro Toshima; Marko Kaksonen; Adam C. Martin; David S King; David G Drubin
Spatial dynamics of receptor-mediated endocytic trafficking in budding yeast revealed by using fluorescent alpha-factor derivatives.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(15):5793-8.
2006: Consuelo Barroso; Stacia E Rodenbusch; Matt D Welch; David G Drubin
A role for cortactin in Listeria monocytogenes invasion of NIH 3T3 cells, but not in its intracellular motility.
Cell motility and the cytoskeleton 2006;63(4):231-43.
2006: Stefan Westermann; Hong-Wei Wang; Agustin Avila-Sakar; David G Drubin; Eva Nogales; Georjana Barnes
The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends.
Nature 2006;440(7083):565-9.
2005: Claire X Zhang; Asa E Y Engqvist-Goldstein; Sebastien Carreno; David J Owen; Elizabeth Smythe; David G Drubin
Multiple roles for cyclin G-associated kinase in clathrin-mediated sorting events.
Traffic (Copenhagen, Denmark) 2005;6(12):1103-13.
2005: Marko Kaksonen; Christopher P Toret; David G Drubin
A modular design for the clathrin- and actin-mediated endocytosis machinery.
Cell 2005;123(2):305-20.
2005: David G Drubin; J Stanley Smith; Wenlei Liu; Wei Zhao; Gary A Chase; Gary A Clawson
Comparison of cryopreservation and standard needle biopsy for gene expression profiling of human breast cancer specimens.
Breast cancer research and treatment 2005;90(1):93-6.
2005: Boris V Strokopytov; Alexander A Fedorov; Nicole Mahoney; Michael kessels; David G Drubin; Steven C Almo
Phased translation function revisited: structure solution of the cofilin-homology domain from yeast actin-binding protein 1 using six-dimensional searches.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 3):285-93.
2005: Junko Toshima; Junko Y Toshima; Adam C. Martin; David G Drubin
Phosphoregulation of Arp2/3-dependent actin assembly during receptor-mediated endocytosis.
Nature cell biology 2005;7(3):246-54.
2005: Yidi Sun; Marko Kaksonen; David T Madden; Randy Schekman; David G Drubin
Interaction of Sla2p's ANTH domain with PtdIns(4,5)P2 is important for actin-dependent endocytic internalization.
Molecular biology of the cell 2005;16(2):717-30.
2005: Stefan Westermann; Agustin Avila-Sakar; Hong-Wei Wang; Hanspeter Niederstrasser; Jonathan Wong; David G Drubin; Eva Nogales; Georjana Barnes
Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex.
Molecular cell 2005;17(2):277-90.
2005: Adam C. Martin; Xiao-Ping Xu; Isabelle Rouiller; Marko Kaksonen; Yidi Sun; Lisa Belmont; Niels Volkmann; Dorit Hanein; Matt D Welch; David G Drubin
Effects of Arp2 and Arp3 nucleotide-binding pocket mutations on Arp2/3 complex function.
The Journal of cell biology 2005;168(2):315-28.
2005: David G Drubin; Marko Kaksonen; Christopher P Toret; Yidi Sun
Cytoskeletal networks and pathways involved in endocytosis.
Novartis Foundation symposium 2005;269():35-42; discussion 43-6, 223-30.
2005: Avital A Rodal; Lukasz Kozubowski; Bruce L Goode; David G Drubin; John H Hartwig
Actin and septin ultrastructures at the budding yeast cell cortex.
Molecular biology of the cell 2005;16(1):372-84.
2004: Sebastien Carreno; Asa E Y Engqvist-Goldstein; Claire X Zhang; Kent L McDonald; David G Drubin
Actin dynamics coupled to clathrin-coated vesicle formation at the trans-Golgi network.
The Journal of cell biology 2004;165(6):781-8.
2004: Asa E Y Engqvist-Goldstein; Claire X Zhang; Sebastien Carreno; Consuelo Barroso; John Edward Heuser; David G Drubin
RNAi-mediated Hip1R silencing results in stable association between the endocytic machinery and the actin assembly machinery.
Molecular biology of the cell 2004;15(4):1666-79.
2004: Christophe Le Clainche; David G Drubin
Actin lessons from pathogens.
Molecular cell 2004;13(4):453-4.
2003: Marko Kaksonen; Yidi Sun; David G Drubin
A pathway for association of receptors, adaptors, and actin during endocytic internalization.
Cell 2003;115(4):475-87.
2003: Stefan Westermann; Iain M Cheeseman; Scott Anderson; John R Yates; David G Drubin; Georjana Barnes
Architecture of the budding yeast kinetochore reveals a conserved molecular core.
The Journal of cell biology 2003;163(2):215-22.
2003: Kenneth R Henry; Kathleen D'Hondt; Ji Suk Chang; David A Nix; M Jamie T V Cope; Clarence S M Chan; David G Drubin; Sandra K Lemmon
The actin-regulating kinase Prk1p negatively regulates Scd5p, a suppressor of clathrin deficiency, in actin organization and endocytosis.
Current biology : CB 2003;13(17):1564-9.
2003: Mariko Sekiya-Kawasaki; Aaron Chris Groen; M Jamie T V Cope; Marko Kaksonen; Hadiya A Watson; Chao Zhang; Kevan M Shokat; Beverly Wendland; Kent L McDonald; J Michael McCaffery; David G Drubin
Dynamic phosphoregulation of the cortical actin cytoskeleton and endocytic machinery revealed by real-time chemical genetic analysis.
The Journal of cell biology 2003;162(5):765-72.
2003: Ching Shang; Tony R Hazbun; Iain M Cheeseman; Jennifer Aranda; Stanley Fields; David G Drubin; Georjana Barnes
Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p.
Molecular biology of the cell 2003;14(8):3342-55.
2003: Avital A Rodal; Amity L Manning; Bruce L Goode; David G Drubin
Negative regulation of yeast WASp by two SH3 domain-containing proteins.
Current biology : CB 2003;13(12):1000-8.
2003: S Vorobiev; B Strokopytov; David G Drubin; C Frieden; S Ono; John Condeelis; Peter A Rubenstein; Steven C Almo
The structure of nonvertebrate actin: implications for the ATP hydrolytic mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5760-5.
2003: Daria E Siekhaus; David G Drubin
Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant.
Nature cell biology 2003;5(3):231-5.
2003: Adam C. Martin; David G Drubin
Impact of genome-wide functional analyses on cell biology research.
Current opinion in cell biology 2003;15(1):6-13.
2003: Asa E Y Engqvist-Goldstein; David G Drubin
Actin assembly and endocytosis: from yeast to mammals.
Annual review of cell and developmental biology 2003;19():287-332.
2002: Christine L Humphries; Heath I Balcer; Jessica L D'Agostino; Barbara Winsor; David G Drubin; Georjana Barnes; Brenda J Andrews; Bruce L Goode
Direct regulation of Arp2/3 complex activity and function by the actin binding protein coronin.
The Journal of cell biology 2002;159(6):993-1004.
2002: Iain M Cheeseman; Scott Anderson; Miri Jwa; Erin M Green; John R Yates; Clarence S M Chan; David G Drubin; Jung seog Kang; Georjana Barnes
Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p.
Cell 2002;111(2):163-72.
2002: Eric L. Weiss; Cornelia Kurischko; Chao Zhang; Kevan M Shokat; David G Drubin; Francis C Luca
The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factor.
The Journal of cell biology 2002;158(5):885-900.
2002: Iain M Cheeseman; David G Drubin; Georjana Barnes
Simple centromere, complex kinetochore: linking spindle microtubules and centromeric DNA in budding yeast.
The Journal of cell biology 2002;157(2):199-203.
2002: Barbara Fazi; M Jamie T V Cope; Alice Douangamath; Silvia Ferracuti; Katja Schirwitz; Adriana Zucconi; David G Drubin; Matthias Wilmanns; Gianni Cesareni; Luisa Castagnoli
Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis.
The Journal of biological chemistry 2002;277(7):5290-8.
2002: Avital A Rodal; Mara C Duncan; David G Drubin
Purification of glutathione S-transferase fusion proteins from yeast.
Methods in enzymology 2002;351():168-72.
2001: Iain M Cheeseman; C Brew; Michael J Wolyniak; A Desai; Scott Anderson; N Muster; John R Yates; T C Huffaker; David G Drubin; Georjana Barnes
Implication of a novel multiprotein Dam1p complex in outer kinetochore function.
The Journal of cell biology 2001;155(7):1137-45.
2001: EM Bennett; Chih-Ying Chen; Asa E Y Engqvist-Goldstein; David G Drubin; Frances M Brodsky
Clathrin hub expression dissociates the actin-binding protein Hip1R from coated pits and disrupts their alignment with the actin cytoskeleton.
Traffic (Copenhagen, Denmark) 2001;2(11):851-8.
2001: Hadiya A Watson; M Jamie T V Cope; A C Groen; David G Drubin; Beverly Wendland
In vivo role for actin-regulating kinases in endocytosis and yeast epsin phosphorylation.
Molecular biology of the cell 2001;12(11):3668-79.
2001: Asa E Y Engqvist-Goldstein; R A Warren; Michael kessels; James H Keen; John Edward Heuser; David G Drubin
The actin-binding protein Hip1R associates with clathrin during early stages of endocytosis and promotes clathrin assembly in vitro.
The Journal of cell biology 2001;154(6):1209-23.
2001: M Enquist-Newman; Iain M Cheeseman; D Van Goor; David G Drubin; Pamela B Meluh; Georjana Barnes
Dad1p, third component of the Duo1p/Dam1p complex involved in kinetochore function and mitotic spindle integrity.
Molecular biology of the cell 2001;12(9):2601-13.
2001: Becky Drees; Bryan A Sundin; E Brazeau; Juliane P Caviston; GC Chen; Wei Guo; Keith G Kozminski; M W Lau; J J Moskow; A Tong; Laura R Schenkman; A McKenzie; Patrick Brennwald; Mark S Longtine; Erfei Bi; C Chan; Peter Novick; Charles Boone; John R Pringle; Trisha Davis; Stanley Fields; David G Drubin
A protein interaction map for cell polarity development.
The Journal of cell biology 2001;154(3):549-71.
2001: Mara C Duncan; M Jamie T V Cope; Bruce L Goode; Beverly Wendland; David G Drubin
Yeast Eps15-like endocytic protein, Pan1p, activates the Arp2/3 complex.
Nature cell biology 2001;3(7):687-90.
2001: Bruce L Goode; Avital A Rodal; Georjana Barnes; David G Drubin
Activation of the Arp2/3 complex by the actin filament binding protein Abp1p.
The Journal of cell biology 2001;153(3):627-34.
2001: Michael kessels; Asa E Y Engqvist-Goldstein; David G Drubin; Britta Qualmann
Mammalian Abp1, a signal-responsive F-actin-binding protein, links the actin cytoskeleton to endocytosis via the GTPase dynamin.
The Journal of cell biology 2001;153(2):351-66.
2001: Scott Bidlingmaier; Eric L. Weiss; C Seidel; David G Drubin; Michael Snyder
The Cbk1p pathway is important for polarized cell growth and cell separation in Saccharomyces cerevisiae.
Molecular and cellular biology 2001;21(7):2449-62.
2001: Iain M Cheeseman; M Enquist-Newman; T Müller-Reichert; David G Drubin; Georjana Barnes
Mitotic spindle integrity and kinetochore function linked by the Duo1p/Dam1p complex.
The Journal of cell biology 2001;152(1):197-212.
2001: Lisa Belmont; David G Drubin
Actin structure function relationships revealed by yeast molecular genetics.
Results and problems in cell differentiation 2001;32():103-21.
2000: Vikramjit Chopra; Martina Metzler; Dita M Rasper; Asa E Y Engqvist-Goldstein; Roshni R Singaraja; Lu Gan; Keith Fichter; Krista McCutcheon; David G Drubin; Donald W Nicholson; Michael R Hayden
HIP12 is a non-proapoptotic member of a gene family including HIP1, an interacting protein with huntingtin.
Mammalian genome : official journal of the International Mammalian Genome Society 2000;11(11):1006-15.
2000: Eric L. Weiss; A C Bishop; Kevan M Shokat; David G Drubin
Chemical genetic analysis of the budding-yeast p21-activated kinase Cla4p.
Nature cell biology 2000;2(10):677-85.
2000: A K Wolven; Lisa Belmont; Nicole Mahoney; Steven C Almo; David G Drubin
In vivo importance of actin nucleotide exchange catalyzed by profilin.
The Journal of cell biology 2000;150(4):895-904.
2000: Bruce L Goode; David G Drubin; Georjana Barnes
Functional cooperation between the microtubule and actin cytoskeletons.
Current opinion in cell biology 2000;12(1):63-71.
2000: Michael kessels; Asa E Y Engqvist-Goldstein; David G Drubin
Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation.
Molecular biology of the cell 2000;11(1):393-412.
2000: Keith G Kozminski; Anthony J-W Chen; Avital A Rodal; David G Drubin
Functions and functional domains of the GTPase Cdc42p.
Molecular biology of the cell 2000;11(1):339-54.
1999: Asa E Y Engqvist-Goldstein; Michael kessels; Vikramjit Chopra; Michael R Hayden; David G Drubin
An actin-binding protein of the Sla2/Huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles.
The Journal of cell biology 1999;147(7):1503-18.
1999: S Yang; M Jamie T V Cope; David G Drubin
Sla2p is associated with the yeast cortical actin cytoskeleton via redundant localization signals.
Molecular biology of the cell 1999;10(7):2265-83.
1999: Avital A Rodal; J W Tetreault; Pekka Lappalainen; David G Drubin; D C Amberg
Aip1p interacts with cofilin to disassemble actin filaments.
The Journal of cell biology 1999;145(6):1251-64.
1999: Lisa Belmont; G M Patterson; David G Drubin
New actin mutants allow further characterization of the nucleotide binding cleft and drug binding sites.
Journal of cell science 1999;112 ( Pt 9)():1325-36.
1999: Kathryn R Ayscough; J J Eby; T Lila; Hilary Dewar; Keith G Kozminski; David G Drubin
Sla1p is a functionally modular component of the yeast cortical actin cytoskeleton required for correct localization of both Rho1p-GTPase and Sla2p, a protein with talin homology.
Molecular biology of the cell 1999;10(4):1061-75.
1999: M Jamie T V Cope; S Yang; C Shang; David G Drubin
Novel protein kinases Ark1p and Prk1p associate with and regulate the cortical actin cytoskeleton in budding yeast.
The Journal of cell biology 1999;144(6):1203-18.
1999: Ira J Blader; M J Cope; Trevor Jackson; A A Profit; A F Greenwood; David G Drubin; Glenn D Prestwich; Anne Theibert
GCS1, an Arf guanosine triphosphatase-activating protein in Saccharomyces cerevisiae, is required for normal actin cytoskeletal organization in vivo and stimulates actin polymerization in vitro.
Molecular biology of the cell 1999;10(3):581-96.
1999: Bruce L Goode; J J Wong; A C Butty; M Peter; A L McCormack; John R Yates; David G Drubin; Georjana Barnes
Coronin promotes the rapid assembly and cross-linking of actin filaments and may link the actin and microtubule cytoskeletons in yeast.
The Journal of cell biology 1999;144(1):83-98.
1999: Lisa Belmont; A Orlova; David G Drubin; E H Egelman
A change in actin conformation associated with filament instability after Pi release.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(1):29-34.
1998: C Hofmann; Iain M Cheeseman; Bruce L Goode; Kent L McDonald; Georjana Barnes; David G Drubin
Saccharomyces cerevisiae Duo1p and Dam1p, novel proteins involved in mitotic spindle function.
The Journal of cell biology 1998;143(4):1029-40.
1998: Lisa Belmont; David G Drubin
The yeast V159N actin mutant reveals roles for actin dynamics in vivo.
The Journal of cell biology 1998;142(5):1289-99.
1998: J J Eby; Stephen P Holly; F van Drogen; A V Grishin; M Peter; David G Drubin; Kendall J Blumer
Actin cytoskeleton organization regulated by the PAK family of protein kinases.
Current biology : CB 1998;8(17):967-70.
1998: Bruce L Goode; David G Drubin; Pekka Lappalainen
Regulation of the cortical actin cytoskeleton in budding yeast by twinfilin, a ubiquitous actin monomer-sequestering protein.
The Journal of cell biology 1998;142(3):723-33.
1998: Pekka Lappalainen; Michael kessels; M Jamie T V Cope; David G Drubin
The ADF homology (ADF-H) domain: a highly exploited actin-binding module.
Molecular biology of the cell 1998;9(8):1951-9.
1998: Kathryn R Ayscough; David G Drubin
A role for the yeast actin cytoskeleton in pheromone receptor clustering and signalling.
Current biology : CB 1998;8(16):927-30.
1997: Pekka Lappalainen; Elena V Fedorov; Alexander A Fedorov; Steven C Almo; David G Drubin
Essential functions and actin-binding surfaces of yeast cofilin revealed by systematic mutagenesis.
The EMBO journal 1997;16(18):5520-30.
1997: Pekka Lappalainen; David G Drubin
Cofilin promotes rapid actin filament turnover in vivo.
Nature 1997;388(6637):78-82.
1997: Alexander A Fedorov; Pekka Lappalainen; Elena V Fedorov; David G Drubin; Steven C Almo
Structure determination of yeast cofilin.
Nature structural biology 1997;4(5):366-9.
1997: Kathryn R Ayscough; J Stryker; Navin Pokala; M Sanders; Phillip Crews; David G Drubin
High rates of actin filament turnover in budding yeast and roles for actin in establishment and maintenance of cell polarity revealed using the actin inhibitor latrunculin-A.
The Journal of cell biology 1997;137(2):399-416.
1997: Fred Chang; David G Drubin; Paul Nurse
cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin.
The Journal of cell biology 1997;137(1):169-82.
1997: A L McCormack; DM Schieltz; Bruce L Goode; S Yang; G Barnes; David G Drubin; John R Yates
Direct analysis and identification of proteins in mixtures by LC/MS/MS and database searching at the low-femtomole level.
Analytical chemistry 1997;69(4):767-76.
1997: T Lila; David G Drubin
Evidence for physical and functional interactions among two Saccharomyces cerevisiae SH3 domain proteins, an adenylyl cyclase-associated protein and the actin cytoskeleton.
Molecular biology of the cell 1997;8(2):367-85.
1997: S Yang; Kathryn R Ayscough; David G Drubin
A role for the actin cytoskeleton of Saccharomyces cerevisiae in bipolar bud-site selection.
The Journal of cell biology 1997;136(1):111-23.
1996: Fred Chang; David G Drubin
Cell division: why daughters cannot be like their mothers.
Current biology : CB 1996;6(6):651-4.
1996: David G Drubin; W J Nelson
Origins of cell polarity.
Cell 1996;84(3):335-44.
1996: N L Freeman; T Lila; K A Mintzer; Z Chen; AJ Pahk; Ruibao Ren; David G Drubin; Jeffrey Field
A conserved proline-rich region of the Saccharomyces cerevisiae cyclase-associated protein binds SH3 domains and modulates cytoskeletal localization.
Molecular and cellular biology 1996;16(2):548-56.
1996: Kathryn R Ayscough; David G Drubin
ACTIN: general principles from studies in yeast.
Annual review of cell and developmental biology 1996;12():129-60.
1995: A Moon; David G Drubin
The ADF/cofilin proteins: stimulus-responsive modulators of actin dynamics.
Molecular biology of the cell 1995;6(11):1423-31.
1995: R Li; Y Zheng; David G Drubin
Regulation of cortical actin cytoskeleton assembly during polarized cell growth in budding yeast.
The Journal of cell biology 1995;128(4):599-615.
1994: D B Vinh; David G Drubin
A yeast TCP-1-like protein is required for actin function in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):9116-20.
1994: D A Holtzman; K F Wertman; David G Drubin
Mapping actin surfaces required for functional interactions in vivo.
The Journal of cell biology 1994;126(2):423-32.
1994: Matt D Welch; David G Drubin
A nuclear protein with sequence similarity to proteins implicated in human acute leukemias is important for cellular morphogenesis and actin cytoskeletal function in Saccharomyces cerevisiae.
Molecular biology of the cell 1994;5(6):617-32.
1994: J Mulholland; D Preuss; A Moon; A Wong; David G Drubin; David Botstein
Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane.
The Journal of cell biology 1994;125(2):381-91.
1994: Matt D Welch; D A Holtzman; David G Drubin
The yeast actin cytoskeleton.
Current opinion in cell biology 1994;6(1):110-9.
1993: David G Drubin; H D Jones; K F Wertman
Actin structure and function: roles in mitochondrial organization and morphogenesis in budding yeast and identification of the phalloidin-binding site.
Molecular biology of the cell 1993;4(12):1277-94.
1993: D B Vinh; Matt D Welch; A K Corsi; K F Wertman; David G Drubin
Genetic evidence for functional interactions between actin noncomplementing (Anc) gene products and actin cytoskeletal proteins in Saccharomyces cerevisiae.
Genetics 1993;135(2):275-86.
1993: Matt D Welch; D B Vinh; H H Okamura; David G Drubin
Screens for extragenic mutations that fail to complement act1 alleles identify genes that are important for actin function in Saccharomyces cerevisiae.
Genetics 1993;135(2):265-74.
1993: D A Holtzman; S Yang; David G Drubin
Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae.
The Journal of cell biology 1993;122(3):635-44.
1993: Alison E Adams; J A Cooper; David G Drubin
Unexpected combinations of null mutations in genes encoding the actin cytoskeleton are lethal in yeast.
Molecular biology of the cell 1993;4(5):459-68.
1993: Viktor Magdolen; David G Drubin; G Mages; Wolfhard Bandlow
High levels of profilin suppress the lethality caused by overproduction of actin in yeast cells.
FEBS letters 1993;316(1):41-7.
1993: A L Moon; P A Janmey; K A Louie; David G Drubin
Cofilin is an essential component of the yeast cortical cytoskeleton.
The Journal of cell biology 1993;120(2):421-35.
1993: H D Jones; Manfred Schliwa; David G Drubin
Video microscopy of organelle inheritance and motility in budding yeast.
Cell motility and the cytoskeleton 1993;25(2):129-42.
1992: K F Wertman; David G Drubin
Actin constitution: guaranteeing the right to assemble.
Science (New York, N.Y.) 1992;258(5083):759-60.
1992: K F Wertman; David G Drubin; D Botstein
Systematic mutational analysis of the yeast ACT1 gene.
Genetics 1992;132(2):337-50.
1992: S J Kron; David G Drubin; David Botstein; James A Spudich
Yeast actin filaments display ATP-dependent sliding movement over surfaces coated with rabbit muscle myosin.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4466-70.
1992: E B Read; H H Okamura; David G Drubin
Actin- and tubulin-dependent functions during Saccharomyces cerevisiae mating projection formation.
Molecular biology of the cell 1992;3(4):429-44.
1991: Alison E Adams; David Botstein; David G Drubin
Requirement of yeast fimbrin for actin organization and morphogenesis in vivo.
Nature 1991;354(6352):404-8.
1991: David G Drubin
Development of cell polarity in budding yeast.
Cell 1991;65(7):1093-6.
1991: J R Pringle; Alison E Adams; David G Drubin; B K Haarer
Immunofluorescence methods for yeast.
Methods in enzymology 1991;194():565-602.
1990: G Barnes; David G Drubin; T Stearns
The cytoskeleton of Saccharomyces cerevisiae.
Current opinion in cell biology 1990;2(1):109-15.
1990: David G Drubin; J Mulholland; Z M Zhu; David Botstein
Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I.
Nature 1990;343(6255):288-90.
1990: David G Drubin
Actin and actin-binding proteins in yeast.
Cell motility and the cytoskeleton 1990;15(1):7-11.
1989: Alison E Adams; David Botstein; David G Drubin
A yeast actin-binding protein is encoded by SAC6, a gene found by suppression of an actin mutation.
Science (New York, N.Y.) 1989;243(4888):231-3.
1989: David G Drubin
The yeast Saccharomyces cerevisiae as a model organism for the cytoskeleton and cell biology.
Cell motility and the cytoskeleton 1989;14(1):42-9.
1989: John R Pringle; R A Preston; Alison E Adams; T Stearns; David G Drubin; B K Haarer; E W Jones
Fluorescence microscopy methods for yeast.
Methods in cell biology 1989;31():357-435.
1988: David G Drubin; K G Miller; David Botstein
Yeast actin-binding proteins: evidence for a role in morphogenesis.
The Journal of cell biology 1988;107(6 Pt 2):2551-61.
1988: David G Drubin; S Kobayashi; Doug R Kellogg; M Kirschner
Regulation of microtubule protein levels during cellular morphogenesis in nerve growth factor-treated PC12 cells.
The Journal of cell biology 1988;106(5):1583-91.
1986: David G Drubin; M W Kirschner
Tau protein function in living cells.
The Journal of cell biology 1986;103(6 Pt 2):2739-46.
1986: David G Drubin; M Kirschner
Purification of tau protein from brain.
Methods in enzymology 1986;134():156-60.
1986: David G Drubin; S Kobayashi; M Kirschner
Association of tau protein with microtubules in living cells.
Annals of the New York Academy of Sciences 1986;466():257-68.
1985: David G Drubin; S C Feinstein; E M Shooter; M W Kirschner
Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors.
The Journal of cell biology 1985;101(5 Pt 1):1799-807.
1984: David G Drubin; D Caput; M W Kirschner
Studies on the expression of the microtubule-associated protein, tau, during mouse brain development, with newly isolated complementary DNA probes.
The Journal of cell biology 1984;98(3):1090-7.
1983: S R Pfeffer; David G Drubin; R B Kelly
Identification of three coated vesicle components as alpha- and beta-tubulin linked to a phosphorylated 50,000-dalton polypeptide.
The Journal of cell biology 1983;97(1):40-7.