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Teresa Druck

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Jin Sun; James Liu; Xueliang Pan; Donald Quimby; nicola zanesi; Teresa Druck; Gerd P Pfeifer; Carlo M Croce; Louise Y Fong; Kay Huebner
Effect of zinc supplementation on N-nitrosomethylbenzylamine-induced forestomach tumor development and progression in tumor suppressor-deficient mouse strains.
Kay Huebner; Joshua C Saldivar; Jin Sun; Hidetaka Shibata; Teresa Druck
Hits, Fhits and Nits: beyond enzymatic function.
Jin Sun; Hiroshi Okumura; Martha Yearsley; Wendy Frankel; Louise Y Fong; Teresa Druck; Kay Huebner
Nit1 and Fhit tumor suppressor activities are additive.

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2011: Jin Sun; James Liu; Xueliang Pan; Donald Quimby; nicola zanesi; Teresa Druck; Gerd P Pfeifer; Carlo M Croce; Louise Y Fong; Kay Huebner
Effect of zinc supplementation on N-nitrosomethylbenzylamine-induced forestomach tumor development and progression in tumor suppressor-deficient mouse strains.
Carcinogenesis 2011;32(3):351-8.
2011: Kay Huebner; Joshua C Saldivar; Jin Sun; Hidetaka Shibata; Teresa Druck
Hits, Fhits and Nits: beyond enzymatic function.
Advances in enzyme regulation 2011;51(1):208-17.
2009: Jin Sun; Hiroshi Okumura; Martha Yearsley; Wendy Frankel; Louise Y Fong; Teresa Druck; Kay Huebner
Nit1 and Fhit tumor suppressor activities are additive.
Journal of cellular biochemistry 2009;107(6):1097-106.
2009: Flavia Pichiorri; Hiroshi Okumura; Tatsuya Nakamura; Preston N Garrison; Pierluigi Gasparini; Sung-Suk Suh; Teresa Druck; Kelly A McCorkell; Larry D Barnes; Carlo M Croce; Kay Huebner
Correlation of fragile histidine triad (Fhit) protein structural features with effector interactions and biological functions.
The Journal of biological chemistry 2009;284(2):1040-9.
2008: Hideshi Ishii; Koshi Mimori; Kazuhiro Ishikawa; Hiroshi Okumura; Flavia Pichiorri; Teresa Druck; Hiroshi Inoue; Andrea Vecchione; Toshiyuki Saito; Masaki Mori; Kay Huebner
Fhit-deficient hematopoietic stem cells survive hydroquinone exposure carrying precancerous changes.
Cancer research 2008;68(10):3662-70.
2007: Haiyan R Qin; Dimitrios Iliopoulos; Tatsuya Nakamura; Stefan Costinean; Stefano Volinia; Teresa Druck; Jin Sun; Hiroshi Okumura; Kay Huebner
Wwox suppresses prostate cancer cell growth through modulation of ErbB2-mediated androgen receptor signaling.
Molecular cancer research : MCR 2007;5(9):957-65.
2007: Kelly A McCorkell; Rita Mancini; Z Siprashvili; B L Barnoski; Dimitrios Iliopoulos; Linda D Siracusa; nicola zanesi; Carlo M Croce; Louise Y Y Fong; Teresa Druck; Kay Huebner
Influence of a nonfragile FHIT transgene on murine tumor susceptibility.
Cytogenetic and genome research 2007;118(2-4):196-203.
2007: Dimitrios Iliopoulos; Muller Fabbri; Teresa Druck; Haiyan R Qin; Shuang-Yin Han; Kay Huebner
Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(1):268-74.
2007: Joshua P Cantor; Dimitrios Iliopoulos; Atul S Rao; Teresa Druck; Shuho Semba; Shuang-Yin Han; Kelly A McCorkell; Thiru V Lakshman; Joshua E Collins; Phyllis R Wachsberger; Joseph S Friedberg; Kay Huebner
Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity.
International journal of cancer. Journal international du cancer 2007;120(1):24-31.
2006: Hideshi Ishii; Koshi Mimori; Hiroshi Inoue; Taeko Inageta; Kazuhiro Ishikawa; Shuho Semba; Teresa Druck; Francesco Trapasso; Kenzaburo Tani; Andrea Vecchione; Carlo M Croce; Masaki Mori; Kay Huebner
Fhit modulates the DNA damage checkpoint response.
Cancer research 2006;66(23):11287-92.
2006: Shuho Semba; Shuang-Yin Han; Haiyan R Qin; Kelly A McCorkell; Dimitrios Iliopoulos; yuri pekarsky; Teresa Druck; Francesco Trapasso; Carlo M Croce; Kay Huebner
Biological functions of mammalian Nit1, the counterpart of the invertebrate NitFhit Rosetta stone protein, a possible tumor suppressor.
The Journal of biological chemistry 2006;281(38):28244-53.
2006: Haiyan R Qin; Dimitrios Iliopoulos; Shuho Semba; Muller Fabbri; Teresa Druck; Stefano Volinia; Carlo M Croce; Carl D Morrison; Russell D Klein; Kay Huebner
A role for the WWOX gene in prostate cancer.
Cancer research 2006;66(13):6477-81.
2006: Shuho Semba; Francesco Trapasso; Muller Fabbri; Kelly A McCorkell; Stefano Volinia; Teresa Druck; Dimitrios Iliopoulos; yuri pekarsky; H Ishii; Preston N Garrison; Larry D Barnes; Carlo M Croce; Kay Huebner
Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential.
Oncogene 2006;25(20):2860-72.
2006: Dimitrios Iliopoulos; Gulnur Guler; Shuang-Yin Han; Teresa Druck; Michelle Ottey; Kelly A McCorkell; Kay Huebner
Roles of FHIT and WWOX fragile genes in cancer.
Cancer letters 2006;232(1):27-36.
2005: Dimitrios Iliopoulos; Gulnur Guler; Shuang-Yin Han; Danika Johnston; Teresa Druck; Kelly A McCorkell; Juan P Palazzo; Peter McCue; Raffaele Baffa; Kay Huebner
Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer.
Oncogene 2005;24(9):1625-33.
2004: Michelle Ottey; Shuang-Yin Han; Teresa Druck; B L Barnoski; Kelly A McCorkell; Carlo M Croce; Carmen Raventos-Suarez; C R Fairchild; Ya Wang; Kay Huebner
Fhit-deficient normal and cancer cells are mitomycin C and UVC resistant.
British journal of cancer 2004;91(9):1669-77.
2004: Shuang-Yin Han; Dimitrios Iliopoulos; Teresa Druck; Gulnur Guler; Clinton J Grubbs; Michael Pereira; Zhongqiu Zhang; Ming You; Ronald A Lubet; Louise Y Y Fong; Kay Huebner
CpG methylation in the Fhit regulatory region: relation to Fhit expression in murine tumors.
Oncogene 2004;23(22):3990-8.
2004: Rami I Aqeilan; yuri pekarsky; Juan J Herrero; Alexey Palamarchuk; Jean Letofsky; Teresa Druck; Francesco Trapasso; Shuang-Yin Han; Gerry Melino; Kay Huebner; Carlo M Croce
Functional association between Wwox tumor suppressor protein and p73, a p53 homolog.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4401-6.
2003: Hideshi Ishii; Andrea Vecchione; Yutaka Furukawa; Krittaya Sutheesophon; Shuang-Yin Han; Teresa Druck; Tamotsu Kuroki; Francesco Trapasso; Miki Nishimura; Yasushi Saito; Keiya Ozawa; Carlo M Croce; Kay Huebner; Yusuke Furukawa
Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies.
Molecular cancer research : MCR 2003;1(13):940-7.
2003: Shuang-Yin Han; Teresa Druck; Kay Huebner
Candidate tumor suppressor genes at FRA7G are coamplified with MET and do not suppress malignancy in a gastric cancer.
Genomics 2003;81(2):105-7.
2001: nicola zanesi; Vincenzo Fidanza; Louise Y Y Fong; Rita Mancini; Teresa Druck; Mauro Valtieri; T Rüdiger; Peter McCue; Carlo M Croce; Kay Huebner
The tumor spectrum in FHIT-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10250-5.
2001: Kristoffel R Dumon; Hideshi Ishii; Aldo Vecchione; Francesco Trapasso; Gustavo Baldassarre; F Chakrani; Teresa Druck; E F Rosato; Noel N Williams; Raffaele Baffa; Matthew J During; Kay Huebner; Carlo M Croce
Fragile histidine triad expression delays tumor development and induces apoptosis in human pancreatic cancer.
Cancer research 2001;61(12):4827-36.
2001: T Shiraishi; Teresa Druck; Koshi Mimori; J Flomenberg; L Berk; Hansjuerg Alder; W Miller; Kay Huebner; Carlo M Croce
Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5722-7.
2001: J Podolski; Tomasz Byrski; Stanislaw Zajaczek; Teresa Druck; Drazen Zimonjic; N C Popescu; G Kata; A Borowka; Jacek Gronwald; Jan Lubinski; K Huebner
Characterization of a familial RCC-associated t(2;3)(q33;q21) chromosome translocation.
Journal of human genetics 2001;46(12):685-93.
2001: Teresa Druck; J Podolski; Tomasz Byrski; L Wyrwicz; Stanislaw Zajaczek; G Kata; A Borowka; Jan Lubinski; K Huebner
The DIRC1 gene at chromosome 2q33 spans a familial RCC-associated t(2;3)(q33;q21) chromosome translocation.
Journal of human genetics 2001;46(10):583-9.
2000: Louise Y Y Fong; Vincenzo Fidanza; nicola zanesi; L F Lock; Linda D Siracusa; Rita Mancini; Z Siprashvili; Michelle Ottey; S Eric Martin; Teresa Druck; Peter McCue; Carlo M Croce; Kay Huebner
Muir-Torre-like syndrome in Fhit-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4742-7.
1999: Koshi Mimori; Teresa Druck; H Inoue; Hansjuerg Alder; L Berk; Masaki Mori; Kay Huebner; Carlo M Croce
Cancer-specific chromosome alterations in the constitutive fragile region FRA3B.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7456-61.
1998: Albert J Kovatich; DM Friedland; Teresa Druck; P Hadaczek; Kay Huebner; RL Comis; W Hauck; Peter McCue
Molecular alterations to human chromosome 3p loci in neuroendocrine lung tumors.
Cancer 1998;83(6):1109-17.
1998: yuri pekarsky; Teresa Druck; M G Cotticelli; M Ohta; J Shou; Jeannine M Mendrola; JC Montgomery; Arthur M Buchberg; Linda D Siracusa; Giacomo Manenti; L Y Fong; Tommaso A Dragani; Carlo M Croce; Kay Huebner
The murine Fhit locus: isolation, characterization, and expression in normal and tumor cells.
Cancer research 1998;58(15):3401-8.
1998: yuri pekarsky; Manuela Campiglio; Z Siprashvili; Teresa Druck; Yurii Sedkov; Sergei Tillib; A Draganescu; P Wermuth; J H Rothman; Kay Huebner; Arthur M Buchberg; Alexander Mazo; Charles Brenner; Carlo M Croce
Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(15):8744-9.
1998: P Hadaczek; Z Siprashvili; Maciej Markiewski; Wenancjusz Domagala; Teresa Druck; Peter McCue; yuri pekarsky; M Ohta; Kay Huebner; Jan Lubinski
Absence or reduction of Fhit expression in most clear cell renal carcinomas.
Cancer research 1998;58(14):2946-51.
1998: Teresa Druck; L Berk; Kay Huebner
FHITness and cancer.
Oncology research 1998;10(7):341-5.
1998: Kay Huebner; Teresa Druck; Z Siprashvili; Carlo M Croce; Albert J Kovatich; Peter McCue
The role of deletions at the FRA3B/FHIT locus in carcinogenesis.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1998;154():200-15.
1997: H Inoue; Hideshi Ishii; Hansjuerg Alder; E Snyder; Teresa Druck; Kay Huebner; Carlo M Croce
Sequence of the FRA3B common fragile region: implications for the mechanism of FHIT deletion.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14584-9.
1997: R Prasad; A B Zhadanov; Yurii Sedkov; Florencia Bullrich; Teresa Druck; R Rallapalli; T Yano; Hansjuerg Alder; Carlo M Croce; Kay Huebner; Alexander Mazo; Eli Canaani
Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax.
Oncogene 1997;15(5):549-60.
1997: Kay Huebner; P Hadaczek; Z Siprashvili; Teresa Druck; Carlo M Croce
The FHIT gene, a multiple tumor suppressor gene encompassing the carcinogen sensitive chromosome fragile site, FRA3B.
Biochimica et biophysica acta 1997;1332(3):M65-70.
1997: R Martinez; D Venturelli; Danilo Perrotti; Maria L Veronese; K Kastury; Teresa Druck; Kay Huebner; Bruno Calabretta
Gene structure, promoter activity, and chromosomal location of the DR-nm23 gene, a related member of the nm23 gene family.
Cancer research 1997;57(6):1180-7.
1997: Drazen Zimonjic; Teresa Druck; M Ohta; K Kastury; Carlo M Croce; Nicholas C Popescu; Kay Huebner
Positions of chromosome 3p14.2 fragile sites (FRA3B) within the FHIT gene.
Cancer research 1997;57(6):1166-70.
1997: S Steelman; John Moskow; K Muzynski; C North; Teresa Druck; JC Montgomery; K Huebner; Ira O Daar; Arthur M Buchberg
Identification of a conserved family of Meis1-related homeobox genes.
Genome research 1997;7(2):142-56.
1997: Teresa Druck; P Hadaczek; T B Fu; M Ohta; Z Siprashvili; Raffaele Baffa; Massimo Negrini; K Kastury; Maria L Veronese; D Rosen; J Rothstein; Peter McCue; M G Cotticelli; H Inoue; Carlo M Croce; Kay Huebner
Structure and expression of the human FHIT gene in normal and tumor cells.
Cancer research 1997;57(3):504-12.
1996: Massimo Negrini; Carmen Monaco; I Vorechovsky; M Ohta; Teresa Druck; Raffaele Baffa; Kay Huebner; Carlo M Croce
The FHIT gene at 3p14.2 is abnormal in breast carcinomas.
Cancer research 1996;56(14):3173-9.
1996: D Chou; T Miyashita; Harvey W Mohrenweiser; K Ueki; K Kastury; Teresa Druck; A von Deimling; Kay Huebner; J C Reed; David N Louis
The BAX gene maps to the glioma candidate region at 19q13.3, but is not altered in human gliomas.
Cancer genetics and cytogenetics 1996;88(2):136-40.
1996: K Kastury; M Ohta; J Lasota; D Moir; T Dorman; S LaForgia; Teresa Druck; Kay Huebner
Structure of the human receptor tyrosine phosphatase gamma gene (PTPRG) and relation to the familial RCC t(3;8) chromosome translocation.
Genomics 1996;32(2):225-35.
1996: K Kastury; Raffaele Baffa; Teresa Druck; M Ohta; M G Cotticelli; H Inoue; Massimo Negrini; M Rugge; D Huang; Carlo M Croce; J Palazzo; Kay Huebner
Potential gastrointestinal tumor suppressor locus at the 3p14.2 FRA3B site identified by homozygous deletions in tumor cell lines.
Cancer research 1996;56(5):978-83.
1996: M Ohta; H Inoue; M G Cotticelli; K Kastury; Raffaele Baffa; J Palazzo; Z Siprashvili; Masaki Mori; Peter McCue; Teresa Druck; Carlo M Croce; Kay Huebner
The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers.
Cell 1996;84(4):587-97.
1995: Teresa Druck; K Kastury; P Hadaczek; J Podolski; A Toloczko; A Sikorski; M Ohta; S LaForgia; J Lasota; Peter McCue
Loss of heterozygosity at the familial RCC t(3;8) locus in most clear cell renal carcinomas.
Cancer research 1995;55(22):5348-53.
1995: Teresa Druck; Yansong Gu; G Prabhala; Linda Cannizzaro; S H Park; Kay Huebner; J H Keen
Chromosome localization of human genes for clathrin adaptor polypeptides AP2 beta and AP50 and the clathrin-binding protein, VCP.
Genomics 1995;30(1):94-7.
1995: Elena Feinstein; Teresa Druck; K Kastury; Hanna Berissi; S A Goodart; J Overhauser; Adi Kimchi; Kay Huebner
Assignment of DAP1 and DAPK--genes that positively mediate programmed cell death triggered by IFN-gamma--to chromosome regions 5p12.2 and 9q34.1, respectively.
Genomics 1995;29(1):305-7.
1995: Marius Sudol; P Bork; A Einbond; K Kastury; Teresa Druck; Massimo Negrini; Kay Huebner; D Lehman
Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain.
The Journal of biological chemistry 1995;270(24):14733-41.
1995: Florencia Bullrich; TK MacLachlan; Nianli Sang; Teresa Druck; Maria L Veronese; Steven Allen; Nicholas Chiorazzi; Andrew Koff; K Heubner; Carlo M Croce
Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer.
Cancer research 1995;55(6):1199-205.
1995: Florencia Bullrich; Teresa Druck; P Kunapuli; J Gomez; Karen W Gripp; B Schlegelberger; J Lasota; M Aronson; Linda Cannizzaro; Kay Huebner
Chromosomal mapping of the genes GPRK5 and GPRK6 encoding G protein-coupled receptor kinases GRK5 and GRK6.
Cytogenetics and cell genetics 1995;70(3-4):250-4.
1995: A C Argeson; Teresa Druck; Maria L Veronese; J L Knopf; Arthur M Buchberg; Kay Huebner; Linda D Siracusa
Phospholipase C gamma-2 (Plcg2) and phospholipase C gamma-1 (Plcg1) map to distinct regions in the human and mouse genomes.
Genomics 1995;25(1):29-35.
1994: W T Wong; Francesca Carlomagno; Teresa Druck; C Barletta; C M Croce; Kay Huebner; M H Kraus; Pier Paolo Di Fiore
Evolutionary conservation of the EPS8 gene and its mapping to human chromosome 12q23-q24.
Oncogene 1994;9(10):3057-61.
1994: Jan Lubinski; P Hadaczek; J Podolski; A Toloczko; A Sikorski; Peter McCue; Teresa Druck; Kay Huebner
Common regions of deletion in chromosome regions 3p12 and 3p14.2 in primary clear cell renal carcinomas.
Cancer research 1994;54(14):3710-3.
1994: Kay Huebner; K Kastury; Teresa Druck; Anna Elisabetta Salcini; Luisa Lanfrancone; Giuliana Pelicci; E Lowenstein; W Li; S H Park; Linda Cannizzaro
Chromosome locations of genes encoding human signal transduction adapter proteins, Nck (NCK), Shc (SHC1), and Grb2 (GRB2).
Genomics 1994;22(2):281-7.
1994: K Kastury; Teresa Druck; Kay Huebner; C Barletta; Dario Acampora; A Simeone; Antonio Faiella; Edoardo Boncinelli
Chromosome locations of human EMX and OTX genes.
Genomics 1994;22(1):41-5.
1994: W T Wong; M H Kraus; Francesca Carlomagno; A Zelano; Teresa Druck; C M Croce; Kay Huebner; Pier Paolo Di Fiore
The human eps15 gene, encoding a tyrosine kinase substrate, is conserved in evolution and maps to 1p31-p32.
Oncogene 1994;9(6):1591-7.
1994: K Kastury; J Li; Teresa Druck; H Su; P K Vogt; Carlo M Croce; Kay Huebner
The human homologue of the retroviral oncogene qin maps to chromosome 14q13.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):3616-8.
1994: A Simeone; Dario Acampora; M Pannese; Maurizio D'Esposito; A Stornaiuolo; Massimo Gulisano; Antonello Mallamaci; K Kastury; Teresa Druck; Kay Huebner
Cloning and characterization of two members of the vertebrate Dlx gene family.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2250-4.
1993: S LaForgia; J Lasota; F Latif; L Boghosian-Sell; K Kastury; M Ohta; Teresa Druck; L Atchison; Linda Cannizzaro; Gilad Barnea
Detailed genetic and physical map of the 3p chromosome region surrounding the familial renal cell carcinoma chromosome translocation, t(3;8)(p14.2;q24.1).
Cancer research 1993;53(13):3118-24.
1993: G Pengue; V Calabrò; P Cannada-Bartoli; P De Luca; Teresa Esposito; P Taillon-Miller; S LaForgia; Teresa Druck; Kay Huebner; Michele D'Urso
YAC-assisted cloning of transcribed sequences from the human chromosome 3p21 region.
Human molecular genetics 1993;2(6):791-6.
1993: J B Levy; P D Canoll; O Silvennoinen; Gilad Barnea; B Morse; A M Honegger; J T Huang; Linda Cannizzaro; S H Park; Teresa Druck
The cloning of a receptor-type protein tyrosine phosphatase expressed in the central nervous system.
The Journal of biological chemistry 1993;268(14):10573-81.
1993: Z Lou; K Kastury; Pamela Crilley; J Lasota; Teresa Druck; Carlo M Croce; Kay Huebner
Characterization of human bone marrow-derived closed circular DNA clones.
Genes, chromosomes & cancer 1993;7(1):15-27.
1993: Kay Huebner; Teresa Druck; S LaForgia; J Lasota; Carlo M Croce; Luisa Lanfrancone; Emilio Donti; G Pengue; Girolama La Mantia; Pier Giuseppe Pelicci
Chromosomal localization of four human zinc finger cDNAs.
Human genetics 1993;91(3):217-22.
1993: K K Wary; Z Lou; Arthur M Buchberg; Linda D Siracusa; Teresa Druck; S LaForgia; Kay Huebner
A homozygous deletion within the carbonic anhydrase-like domain of the Ptprg gene in murine L-cells.
Cancer research 1993;53(7):1498-502.
1992: Douglas Pat Cerretti; Carl J Kozlosky; B Mosley; N Nelson; K Van Ness; T A Greenstreet; CJ March; S R Kronheim; Teresa Druck; Linda Cannizzaro
Molecular cloning of the interleukin-1 beta converting enzyme.
Science (New York, N.Y.) 1992;256(5053):97-100.
1992: G Sithanandam; Teresa Druck; Linda Cannizzaro; G Leuzzi; K Huebner; U R Rapp
B-raf and a B-raf pseudogene are located on 7q in man.
Oncogene 1992;7(4):795-9.
1991: C Cyr; Kay Huebner; Teresa Druck; R Kris
Cloning and chromosomal localization of a human endothelin ETA receptor.
Biochemical and biophysical research communications 1991;181(1):184-90.
1991: C Barletta; Teresa Druck; S LaForgia; B Calabretta; Harry A Drabkin; D Patterson; Carlo M Croce; Kay Huebner
Chromosome locations of the MYB related genes, AMYB and BMYB.
Cancer research 1991;51(14):3821-4.