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Gina D'Suze

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

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Alfredo Mijares; Patricia Díaz; Gina D'Suze; Victor Salazar; Hilda Vázquez
High resolution fluorescence microscopy evidence on the transport of immunoglobulins. Differences between mammalian IgG, F(ab')2 and avian IgY.
P Forsyth; Alfredo Mijares; R Martínez; C Castillo; Gina D'Suze
Bactridine's effects on DUM cricket neurons under voltage clamp conditions.
Steve Peigneur; Carlos Sevcik; Jan Tytgat; Cecilia Castillo; Gina D'Suze
Subtype specificity interaction of bactridines with mammalian, insect and bacterial sodium channels under voltage clamp conditions.

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All Publications

2013: Alfredo Mijares; Patricia Díaz; Gina D'Suze; Victor Salazar; Hilda Vázquez
High resolution fluorescence microscopy evidence on the transport of immunoglobulins. Differences between mammalian IgG, F(ab')2 and avian IgY.
Toxicon : official journal of the International Society on Toxinology 2013;63():7-18.
2012: P Forsyth; Alfredo Mijares; R Martínez; C Castillo; Gina D'Suze
Bactridine's effects on DUM cricket neurons under voltage clamp conditions.
Journal of insect physiology 2012;58(12):1676-85.
2012: Steve Peigneur; Carlos Sevcik; Jan Tytgat; Cecilia Castillo; Gina D'Suze
Subtype specificity interaction of bactridines with mammalian, insect and bacterial sodium channels under voltage clamp conditions.
The FEBS journal 2012;279(21):4025-38.
2012: Alfredo Mijares; Patricia Díaz; Gina D'Suze; Victor Salazar; Hilda Vázquez
Horse IgG- and ostrich IgY-F(ab')₂ groups have different affinities for mice erythrocytes and lymphocytes. Implications for avian immunoglobulin therapeutic usefulness.
Toxicon : official journal of the International Society on Toxinology 2012;60(6):1215-21.
2011: Galax Joya; Gina D'Suze; André T S Ferreira; Arnaldo Rosales; Victor Salazar; Alfredo Mijares; Gonzalo Visbal; Jonas Perales
Scorpion toxins modify phytopathogenic fungus physiology. A possible source of new fungicides.
Journal of agricultural and food chemistry 2011;59(11):6327-37.
2011: Josmary Brazón; Craig E Hughes; Jun Mori; Carlos Sevcik; Gina D'Suze; Steve P Watson
Tityus discrepans scorpion venom activates platelets through GPVI and a novel Src-dependent signaling pathway.
Platelets 2011;22(3):165-72.
2010: Gina D'Suze; Carlos Sevcik
Scorpion venom complexity fractal analysis. Its relevance for comparing venoms.
Journal of theoretical biology 2010;267(3):405-16.
2010: Gina D'Suze; Arnaldo Rosales; Víctor Salazar; Carlos Sevcik
Apoptogenic peptides from Tityus discrepans scorpion venom acting against the SKBR3 breast cancer cell line.
Toxicon : official journal of the International Society on Toxinology 2010;56(8):1497-505.
2009: Patricia Díaz; Gina D'Suze; Víctor Salazar; Carlos Sevcik; John D Shannon; Nicholas E Sherman; Jay W Fox
Antibacterial activity of six novel peptides from Tityus discrepans scorpion venom. A fluorescent probe study of microbial membrane Na+ permeability changes.
Toxicon : official journal of the International Society on Toxinology 2009;54(6):802-17.
2009: Gina D'Suze; Elisabeth F Schwartz; B I García-Gómez; Carlos Sevcik; Lourival D Possani
Molecular cloning and nucleotide sequence analysis of genes from a cDNA library of the scorpion Tityus discrepans.
Biochimie 2009;91(8):1010-9.
2009: Josmary Brazón; Gina D'Suze; Maria Lucia D'Errico; Carmen Luisa Arocha-Piñango; Belsy Guerrero
Discreplasminin, a plasmin inhibitor isolated from Tityus discrepans scorpion venom.
Archives of toxicology 2009;83(7):669-78.
2008: Josmary Brazón; Belsy Guerrero; Carmen Luisa Arocha-Piñango; Carlos Sevcik; Gina D'Suze
[Effect of Tityus discrepans scorpion venom on global coagulation test. Preliminary studies].
Investigación clínica 2008;49(1):49-58.
2008: Carlos Sevcik; Patricia Díaz; Gina D'Suze
On the presence of antibodies against bovine, equine and poultry immunoglobulins in human IgG preparations, and its implications on antivenom production.
Toxicon : official journal of the International Society on Toxinology 2008;51(1):10-6.
2007: Gina D'Suze; Patricia Díaz; Victor Salazar; Carlos Sevcik; Josmary Brazón
Effect of leukocyte inhibitors benzydamine and cyclophosphamide, on lung injury caused by Tityus discrepans scorpion venom.
Toxicon : official journal of the International Society on Toxinology 2007;50(8):1116-25.
2007: Carlos Sevcik; Victor Salazar; Patricia Díaz; Gina D'Suze
Initial volume of a drug before it reaches the volume of distribution: pharmacokinetics of F(ab')2 antivenoms and other drugs.
Toxicon : official journal of the International Society on Toxinology 2007;50(5):653-65.
2007: Gina D'Suze; S Moncada; C González; Carlos Sevcik; Alejandro Alagón
Antigenic cross-reactivity between sixteen venoms from scorpions belonging to six genera.
Clinical toxicology (Philadelphia, Pa.) 2007;45(2):158-63.
2007: Elia Diego-García; Elisabeth Schwartz; Gina D'Suze; Sergio A Román González; Cesar V F Batista; Blanca Inés García; Ricardo C Rodríguez de la Vega; Lourival D Possani
Wide phylogenetic distribution of Scorpine and long-chain beta-KTx-like peptides in scorpion venoms: identification of "orphan" components.
Peptides 2007;28(1):31-7.
2006: Cesar V F Batista; Gina D'Suze; Froylan Gómez-Lagunas; Fernando Z Zamudio; Sergio Encarnación; Carlos Sevcik; Lourival D Possani
Proteomic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins.
Proteomics 2006;6(12):3718-27.
2006: Ada Prochnicka-Chalufour; Gerardo Corzo; Honoo Satake; Marie-France Martin-Eauclaire; Anna Rosa Murgia; Gianfranco Prestipino; Gina D'Suze; Lourival D Possani; Muriel DELEPIERRE
Solution structure of discrepin, a new K+-channel blocking peptide from the alpha-KTx15 subfamily.
Biochemistry 2006;45(6):1795-804.
2005: J I Sosa-Rosales; Gina D'Suze; Victor Salazar; J Fox; Carlos Sevcik
Purification of a myotoxin from the toadfish Thalassophryne maculosa (Günter) venom.
Toxicon : official journal of the International Society on Toxinology 2005;45(2):147-53.
2004: Gina D'Suze; Victor Salazar; Patricia Díaz; Carlos Sevcik; H Azpurua; N Bracho
Histopathological changes and inflammatory response induced by Tityus discrepans scorpion venom in rams.
Toxicon : official journal of the International Society on Toxinology 2004;44(8):851-60.
2004: Carlos Sevcik; Gina D'Suze; Patricia Díaz; Victor Salazar; C Hidalgo; H Azpúrua; N Bracho
Modelling Tityus scorpion venom and antivenom pharmacokinetics. Evidence of active immunoglobulin G's F(ab')2 extrusion mechanism from blood to tissues.
Toxicon : official journal of the International Society on Toxinology 2004;44(7):731-41.
2004: Gina D'Suze; Cesar V F Batista; Andrea Frau; Anna Rosa Murgia; Fernando Z Zamudio; Carlos Sevcik; Lourival D Possani; Gianfranco Prestipino
Discrepin, a new peptide of the sub-family alpha-ktx15, isolated from the scorpion Tityus discrepans irreversibly blocks K+ -channels (IA currents) of cerebellum granular cells.
Archives of biochemistry and biophysics 2004;430(2):256-63.
2004: Gina D'Suze; Carlos Sevcik; Miguel Corona; Fernando Z Zamudio; Cesar V F Batista; Fredy I V Coronas; Lourival D Possani
Ardiscretin a novel arthropod-selective toxin from Tityus discrepans scorpion venom.
Toxicon : official journal of the International Society on Toxinology 2004;43(3):263-72.
2003: Ximena Páez; Carmen Amalia Mazzei-Dávila; Belkis Quiñonez; Gina D'Suze; Luis Hernández
[Amino acid changes following intraperitoneal administration of Tityus zulianus scorpion venom in mice. Study with subcutaneous microdialysis and capillary electrophoresis].
Investigación clínica 2003;44(4):291-302.
2003: Carlos Sevcik; J Noriega; Gina D'Suze
Identification of Enterobacter bacteria as saxitoxin producers in cattle's rumen and surface water from Venezuelan Savannahs.
Toxicon : official journal of the International Society on Toxinology 2003;42(4):359-66.
2003: Gina D'Suze; S Moncada; C González; Carlos Sevcik; V Aguilar; Alejandro Alagón
Relationship between plasmatic levels of various cytokines, tumour necrosis factor, enzymes, glucose and venom concentration following Tityus scorpion sting.
Toxicon : official journal of the International Society on Toxinology 2003;41(3):367-75.
2003: Eva Novoa; Gina D'Suze; Michael Winter; Astrid Crespo; Maria A Tortoledo; Héctor Marcano; Eliot Friedman; Carlos Sevcik; Joseph Zabner; Roberto Sánchez de León
The indirect effect of Tityus discrepans on rabbit pulmonary vasculature.
Respiratory physiology & neurobiology 2003;134(1):33-41.
1999: Gina D'Suze; Fernando Z Zamudio; Froylan Gómez-Lagunas; Lourival D Possani
A novel K+ channel blocking toxin from Tityus discrepans scorpion venom.
FEBS letters 1999;456(1):146-8.
1999: Gina D'Suze; Alejandro P Comellas; Liuska Pesce; Carlos Sevcik; R Sanchez-de-León
Tityus discrepans venom produces a respiratory distress syndrome in rabbits through an indirect mechanism.
Toxicon : official journal of the International Society on Toxinology 1999;37(1):173-80.
1997: Gina D'Suze; Carlos Sevcik; J F Pérez; J W Fox
Isolation and characterization of a potent curarizing polypeptide from Tityus discrepans scorpion venom.
Toxicon : official journal of the International Society on Toxinology 1997;35(12):1683-9.
1996: Gina D'Suze; F Corona; Lourival D Possani; Carlos Sevcik
High performance liquid chromatography purification and amino acid sequence of toxins from the muscarinic fraction of Tityus discrepans scorpion venom.
Toxicon : official journal of the International Society on Toxinology 1996;34(5):591-8.
1995: Gina D'Suze; Carlos Sevcik; M Ramos
Presence of curarizing polypeptides and a pancreatitis-inducing fraction without muscarinic effects in the venom of the Venezuelan scorpion Tityus discrepans (Karsch).
Toxicon : official journal of the International Society on Toxinology 1995;33(3):333-45.
1994: Alfredo Mijares; A I García-Rodriguez; Gina D'Suze; Alfredo Jose mijares
Specific blockage of squid axon resting potassium permeability by Haliclona viridis (Porifera: Haliclonidae) toxin (HvTX).
Toxicon : official journal of the International Society on Toxinology 1994;32(7):773-88.
1993: Alfredo Mijares; J C Brito; Gina D'Suze; M G Domínguez-Bello; M Lovera; Alfredo Jose mijares; S Bónoli
Toxicology of a bovine paraplegic syndrome.
Toxicon : official journal of the International Society on Toxinology 1993;31(12):1581-94.
1993: Alfredo Mijares; J C Brito; Gina D'Suze; Alfredo Jose mijares; M G Domínguez
[Toxinology of bovine paraplegic syndrome].
Acta científica venezolana 1993;44(2):131-42.