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Tom Dubbelman

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Laurence L Trannoy; Johan W M Lagerberg; Tom M A R Dubbelman; Hans Schuitmaker; Anneke Brand
Positively charged porphyrins: a new series of photosensitizers for sterilization of RBCs.
J VanSteveninck; Laurence L Trannoy; Geert A J Besselink; Tom M A R Dubbelman; Anneke Brand; Dirk de Korte; Arthur J Verhoeven; Johan W M Lagerberg
Selective protection of RBCs against photodynamic damage by the band 3 ligand dipyridamole.
Odrun A Gederaas; Johan W M Lagerberg; OL Brekke; Kristian Berg; Tom M A R Dubbelman
5-aminolevulinic acid induced lipid peroxidation after light exposure on human colon carcinoma cells and effects of alpha-tocopherol treatment.

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All Publications

2004: Laurence L Trannoy; Johan W M Lagerberg; Tom M A R Dubbelman; Hans Schuitmaker; Anneke Brand
Positively charged porphyrins: a new series of photosensitizers for sterilization of RBCs.
Transfusion 2004;44(8):1186-96.
2000: J VanSteveninck; Laurence L Trannoy; Geert A J Besselink; Tom M A R Dubbelman; Anneke Brand; Dirk de Korte; Arthur J Verhoeven; Johan W M Lagerberg
Selective protection of RBCs against photodynamic damage by the band 3 ligand dipyridamole.
Transfusion 2000;40(11):1330-6.
2000: Odrun A Gederaas; Johan W M Lagerberg; OL Brekke; Kristian Berg; Tom M A R Dubbelman
5-aminolevulinic acid induced lipid peroxidation after light exposure on human colon carcinoma cells and effects of alpha-tocopherol treatment.
Cancer letters 2000;159(1):23-32.
2000: Johan W M Lagerberg; K P Uberriegler; B Krammer; J VanSteveninck; Tom M A R Dubbelman
Plasma membrane properties involved in the photodynamic efficacy of merocyanine 540 and tetrasulfonated aluminum phthalocyanine.
Photochemistry and photobiology 2000;71(3):341-6.
1999: Anne Moor; A van der Veen; Tom M A R Dubbelman; J VanSteveninck; Anneke Brand
Photodynamic sterilization of red cells and its effect on contaminating white cells: viability and mechanism of cell death.
Transfusion 1999;39(6):599-607.
1999: Frederik H E Schagen; Anne Moor; S C Cheong; Steve J Cramer; Hans van Ormondt; Alex J van der Eb; Tom M A R Dubbelman; Rob Hoeben
Photodynamic treatment of adenoviral vectors with visible light: an easy and convenient method for viral inactivation.
Gene therapy 1999;6(5):873-81.
1999: Odrun A Gederaas; M H Rasch; Kristian Berg; Johan W M Lagerberg; Tom M A R Dubbelman
Photodynamically induced effects in colon carcinoma cells (WiDr) by endogenous photosensitizers generated by incubation with 5-aminolaevulinic acid.
Journal of photochemistry and photobiology. B, Biology 1999;49(2-3):162-70.
1999: Helga E de Vries; Anne Moor; Tom M A R Dubbelman; Theo Van berkel; Johan Kuiper
Oxidized low-density lipoprotein as a delivery system for photosensitizers: implications for photodynamic therapy of atherosclerosis.
The Journal of pharmacology and experimental therapeutics 1999;289(1):528-34.
1999: Anne Moor; AE Wagenaars-van Gompel; Ralph Hermanns; J van der Meulen; J Smit; J Wilschut; Anneke Brand; Tom M A R Dubbelman; J VanSteveninck
Inhibition of various steps in the replication cycle of vesicular stomatitis virus contributes to its photoinactivation by AlPcS4 or Pc4 and red light.
Photochemistry and photobiology 1999;69(3):353-9.
1999: Anne Moor; Tom M A R Dubbelman; J VanSteveninck; Anneke Brand
Transfusion-transmitted diseases: risks, prevention and perspectives.
European journal of haematology 1999;62(1):1-18.
1998: Johan W M Lagerberg; J VanSteveninck; Tom M A R Dubbelman
Effect of membrane potential on the binding of merocyanine 540 to human erythrocytes.
Photochemistry and photobiology 1998;67(6):729-33.
1997: Anne Moor; Johan W M Lagerberg; K Tijssen; S Foley; T George Truscott; I E Kochevar; Anneke Brand; Tom M A R Dubbelman; J VanSteveninck
In vitro fluence rate effects in photodynamic reactions with AIPcS4 as sensitizer.
Photochemistry and photobiology 1997;66(6):860-5.
1997: Maryse Hoebeke; Hans Schuitmaker; L E Jannink; Tom M A R Dubbelman; A Jakobs; A Van de Vorst
Electron spin resonance evidence of the generation of superoxide anion, hydroxyl radical and singlet oxygen during the photohemolysis of human erythrocytes with bacteriochlorin a.
Photochemistry and photobiology 1997;66(4):502-8.
1997: M Paardekooper; A W De Bruijne; A E Van Gompel; Richard Verhage; D Averbeck; Tom M A R Dubbelman; P J Van den Broek
Single strand breaks and mutagenesis in yeast induced by photodynamic treatment with chloroaluminum phthalocyanine.
Journal of photochemistry and photobiology. B, Biology 1997;40(2):132-40.
1997: M H Rasch; K Tijssen; Johan W M Lagerberg; Willem E Corver; J VanSteveninck; Tom M A R Dubbelman
The role of protein kinase C activity in the killing of Chinese hamster ovary cells by ionizing radiation and photodynamic treatment.
Photochemistry and photobiology 1997;66(2):209-13.
1997: Anne Moor; A van der Veen; AE Wagenaars-van Gompel; Tom M A R Dubbelman; J VanSteveninck; Anneke Brand
Shelf-life of photodynamically sterilized red cell concentrates with various numbers of white cells.
Transfusion 1997;37(6):592-600.
1997: Johan W M Lagerberg; J VanSteveninck; Tom M A R Dubbelman
Effect of hydrogen peroxide on the binding of Merocyanine 540 to human erythrocytes.
Cellular and molecular life sciences : CMLS 1997;53(3):257-62.
1997: DJ Blom; Hans Schuitmaker; I de Waard-Siebinga; Tom M A R Dubbelman; Martine J Jager
Decreased expression of HLA class I on ocular melanoma cells following in vitro photodynamic therapy.
Cancer letters 1997;112(2):239-43.
1996: M H Rasch; K Tijssen; J VanSteveninck; Tom M A R Dubbelman
Synergistic interaction of photodynamic treatment with the sensitizer aluminum phthalocyanine and hyperthermia on loss of clonogenicity of CHO cells.
Photochemistry and photobiology 1996;64(3):586-93.
1996: Johan W M Lagerberg; M Williams; Anne Moor; Anneke Brand; Jolanda Van der Zee; Tom M A R Dubbelman; J VanSteveninck
The influence of merocyanine 540 and protoporphyrin on physicochemical properties of the erythrocyte membrane.
Biochimica et biophysica acta 1996;1278(2):247-53.
1996: Johan W M Lagerberg; J Vanderwal; P Charlesworth; T George Truscott; Jolanda Van der Zee; H Schneckenburger; Tom M A R Dubbelman
Influence of rhodamine 123 on the photosensitizing properties of porphyrins.
Free radical biology & medicine 1996;21(2):181-8.
1996: E Ben-Hur; Anne Moor; H Margolis-Nunno; P Gottlieb; M M Zuk; S Lustigman; B Horowitz; Anneke Brand; J Van Steveninck; Tom M A R Dubbelman
The photodecontamination of cellular blood components: mechanisms and use of photosensitization in transfusion medicine.
Transfusion medicine reviews 1996;10(1):15-22.
1995: J VanDerWal; W M Lagerberg; Tom M A R Dubbelman; J VanSteveninck
Interaction of photodynamically induced cell killing and dark cytotoxicity of rhodamine 123.
Photochemistry and photobiology 1995;62(4):757-63.
1995: Johan W M Lagerberg; Karl-Josef Kallen; Cees W M Haest; J VanSteveninck; Tom M A R Dubbelman
Factors affecting the amount and the mode of merocyanine 540 binding to the membrane of human erythrocytes. A comparison with the binding to leukemia cells.
Biochimica et biophysica acta 1995;1235(2):428-36.
1995: JJ Schuitmaker; J E Jannink; Tom M A R Dubbelman
Influence of cell culture medium on the photosensitizing effectiveness of bacteriochlorin a.
Journal of photochemistry and photobiology. B, Biology 1995;28(2):143-8.
1994: L C Penning; Johan W M Lagerberg; J H VanDierendonck; Cees J Cornelisse; Tom M A R Dubbelman; J VanSteveninck
The role of DNA damage and inhibition of poly(ADP-ribosyl)ation in loss of clonogenicity of murine L929 fibroblasts, caused by photodynamically induced oxidative stress.
Cancer research 1994;54(21):5561-7.
1994: J VanSteveninck; Johan W M Lagerberg; P Charlesworth; Tom M A R Dubbelman; T George Truscott
Effects of the micro-environment on the photophysical properties of hematoporphyrin.
Biochimica et biophysica acta 1994;1201(1):23-8.
1994: L C Penning; K Tijssen; J P Boegheim; J van Steveninck; Tom M A R Dubbelman
Relationship between photodynamically induced damage to various cellular parameters and loss of clonogenicity in different cell types with hematoporphyrin derivative as sensitizer.
Biochimica et biophysica acta 1994;1221(3):250-8.
1994: L C Penning; Tom M A R Dubbelman
Fundamentals of photodynamic therapy: cellular and biochemical aspects.
Anti-cancer drugs 1994;5(2):139-46.
1994: L C Penning; K Tijssen; J VanSteveninck; Tom M A R Dubbelman
Hematoporphyrin derivative-induced photodynamic inhibition of Na+/K(+)-ATPase in L929 fibroblasts, Chinese hamster ovary cells and T24 human bladder transitional carcinoma cells.
Photochemistry and photobiology 1994;59(3):336-41.
1993: JJ Schuitmaker; R I J Feitsma; Johanna G Journée-de Korver; Tom M A R Dubbelman; Ernest K J Pauwels
Tissue distribution of bacteriochlorin a labelled with 99mTc-pertechnetate in hamster Greene melanoma.
International journal of radiation biology 1993;64(4):451-8.
1993: L C Penning; J VanSteveninck; Tom M A R Dubbelman
HPD-induced photodynamic changes in intracellular cyclic AMP levels in human bladder transitional carcinoma cells, clone T24.
Biochemical and biophysical research communications 1993;194(3):1084-9.
1993: L C Penning; M J Keirse; J VanSteveninck; Tom M A R Dubbelman
Ca(2+)-mediated prostaglandin E2 induction reduces haematoporphyrin-derivative-induced cytotoxicity of T24 human bladder transitional carcinoma cells in vitro.
The Biochemical journal 1993;292 ( Pt 1)():237-40.
1993: Karl-Josef Kallen; Cees W M Haest; J W Langerberg; Tom M A R Dubbelman
Binding-independent fluorescence enhancement of MC 540 in erythrocytes with decreased phospholipid asymmetry.
Biochemical Society transactions 1993;21(2):83S.
1993: Jolanda Van der Zee; B B Krootjes; C F Chignell; Tom M A R Dubbelman; J Van Steveninck
Hydroxyl radical generation by a light-dependent Fenton reaction.
Free radical biology & medicine 1993;14(2):105-13.
1992: G J Boonen; J van Steveninck; Tom M A R Dubbelman; P J van den Broek; JG Elferink
Exocytosis in electropermeabilized neutrophils. Responsiveness to calcium and guanosine 5'-[gamma-thio]triphosphate.
The Biochemical journal 1992;287 ( Pt 3)():695-700.
1992: M Paardekooper; P J Van den Broek; A W De Bruijne; JG Elferink; Tom M A R Dubbelman; J Van Steveninck
Photodynamic treatment of yeast cells with the dye toluidine blue: all-or-none loss of plasma membrane barrier properties.
Biochimica et biophysica acta 1992;1108(1):86-90.
1992: E Ben-Hur; Tom M A R Dubbelman; J Van Steveninck
Effect of fluoride on inhibition of plasma membrane functions in Chinese hamster ovary cells photosensitized by aluminum phthalocyanine.
Radiation research 1992;131(1):47-52.
1992: L C Penning; M H Rasch; E Ben-Hur; Tom M A R Dubbelman; A C Havelaar; Jolanda Van der Zee; J Van Steveninck
A role for the transient increase of cytoplasmic free calcium in cell rescue after photodynamic treatment.
Biochimica et biophysica acta 1992;1107(2):255-60.
1992: E Ben-Hur; Rob Hoeben; Hans van Ormondt; Tom M A R Dubbelman; J Van Steveninck
Photodynamic inactivation of retroviruses by phthalocyanines: the effects of sulphonation, metal ligand and fluoride.
Journal of photochemistry and photobiology. B, Biology 1992;13(2):145-52.
1992: C Prinsze; L C Penning; Tom M A R Dubbelman; J VanSteveninck
Interaction of photodynamic treatment and either hyperthermia or ionizing radiation and of ionizing radiation and hyperthermia with respect to cell killing of L929 fibroblasts, Chinese hamster ovary cells, and T24 human bladder carcinoma cells.
Cancer research 1992;52(1):117-20.
1991: J van Steveninck; M Paardekooper; Tom M A R Dubbelman; E Ben-Hur
Anomalous properties of water in macromolecular gels.
Biochimica et biophysica acta 1991;1115(2):96-100.
1991: E Ben-Hur; Tom M A R Dubbelman; J Van Steveninck
The effect of fluoride on binding and photodynamic action of phthalocyanines with proteins.
Photochemistry and photobiology 1991;54(5):703-7.
1991: JJ Schuitmaker; G F Vrensen; J L van Delft; Didi de Wolff-Rouendaal; Tom M A R Dubbelman; A de Wolf
Morphologic effects of bacteriochlorin a and light in vivo on intraocular melanoma.
Investigative ophthalmology & visual science 1991;32(10):2683-8.
1991: E Ben-Hur; Tom M A R Dubbelman; J Van Steveninck
Phthalocyanine-induced photodynamic changes of cytoplasmic free calcium in Chinese hamster cells.
Photochemistry and photobiology 1991;54(2):163-6.
1991: C Prinsze; K Tijssen; Tom M A R Dubbelman; J Van Steveninck
Potentiation of hyperthermia-induced haemolysis of human erythrocytes by photodynamic treatment. Evidence for the involvement of the anion transporter in this synergistic interaction.
The Biochemical journal 1991;277 ( Pt 1)():183-8.
1991: C Prinsze; Tom M A R Dubbelman; J Van Steveninck
Potentiation of thermal inactivation of glyceraldehyde-3-phosphate dehydrogenase by photodynamic treatment. A possible model for the synergistic interaction between photodynamic therapy and hyperthermia.
The Biochemical journal 1991;276 ( Pt 2)():357-62.
1990: JJ Schuitmaker; Jaap A van Best; J L van Delft; Tom M A R Dubbelman; Jendo A Oosterhuis; Didi de Wolff-Rouendaal
Bacteriochlorin a, a new photosensitizer in photodynamic therapy. In vivo results.
Investigative ophthalmology & visual science 1990;31(8):1444-50.
1990: C Prinsze; Tom M A R Dubbelman; J Van Steveninck
Protein damage, induced by small amounts of photodynamically generated singlet oxygen or hydroxyl radicals.
Biochimica et biophysica acta 1990;1038(2):152-7.
1989: J P Boegheim; Johan W M Lagerberg; K Tijssen; Tom M A R Dubbelman; J Van Steveninck
Preferential uptake of cytotoxic porphyrins from hematoporphyrin derivative in murine L929 fibroblasts and Chinese hamster ovary K1 epithelial cells.
Biochimica et biophysica acta 1989;1012(3):237-42.
1989: B Deuticke; U Henseleit; Cees W M Haest; K B Heller; Tom M A R Dubbelman
Enhancement of transbilayer mobility of a membrane lipid probe accompanies formation of membrane leaks during photodynamic treatment of erythrocytes.
Biochimica et biophysica acta 1989;982(1):53-61.
1989: J Van Steveninck; J F Koster; Tom M A R Dubbelman
Xanthine oxidase-catalysed oxidation of paracetamol.
The Biochemical journal 1989;259(3):633-7.
1989: J Van der Zee; J Van Steveninck; J F Koster; Tom M A R Dubbelman
Inhibition of enzymes and oxidative damage of red blood cells induced by t-butylhydroperoxide-derived radicals.
Biochimica et biophysica acta 1989;980(2):175-80.
1988: J P Boegheim; Johan W M Lagerberg; Tom M A R Dubbelman; K Tijssen; H J Tanke; J Van Der Meulen; J Van Steveninck
Photodynamic effects of hematoporphyrin derivative on the uptake of rhodamine 123 by mitochondria of intact murine L929 fibroblasts and Chinese ovary K1 cells.
Photochemistry and photobiology 1988;48(5):613-20.
1988: J Van Steveninck; J P Boegheim; Tom M A R Dubbelman; J Van der Zee
The influence of porphyrins on iron-catalysed generation of hydroxyl radicals.
The Biochemical journal 1988;250(1):197-201.
1987: E M Beems; Tom M A R Dubbelman; J Lugtenburg; J A Van Best; M F Smeets; J P Boegheim
Photosensitizing properties of bacteriochlorophyllin a and bacteriochlorin a, two derivatives of bacteriochlorophyll a.
Photochemistry and photobiology 1987;46(5):639-43.
1987: Jolanda Van der Zee; E Van Beek; Tom M A R Dubbelman; J Van Steveninck
Toxic effects of ozone on murine L929 fibroblasts. Damage to DNA.
The Biochemical journal 1987;247(1):69-72.
1987: J P Boegheim; H Scholte; Tom M A R Dubbelman; E Beems; A K Raap; J van Steveninck
Photodynamic effects of hematoporphyrin-derivative on enzyme activities of murine L929 fibroblasts.
Journal of photochemistry and photobiology. B, Biology 1987;1(1):61-73.
1987: J Van der Zee; Tom M A R Dubbelman; J Van Steveninck
Toxic effects of ozone on murine L929 fibroblasts. Damaging action on transmembrane transport systems.
The Biochemical journal 1987;245(1):301-4.
1987: J P Boegheim; Tom M A R Dubbelman; L H Mullenders; J Van Steveninck
Photodynamic effects of haematoporphyrin derivative on DNA repair in murine L929 fibroblasts.
The Biochemical journal 1987;244(3):711-5.
1987: J Van Steveninck; J P Boegheim; Tom M A R Dubbelman; J Van der Zee
The mechanism of potentiation of horseradish peroxidase-catalysed oxidation of NADPH by porphyrins.
The Biochemical journal 1987;242(2):611-3.
1986: J Van Steveninck; K Tijssen; J P Boegheim; J Van der Zee; Tom M A R Dubbelman
Photodynamic generation of hydroxyl radicals by hematoporphyrin derivative and light.
Photochemistry and photobiology 1986;44(6):711-6.
1985: J van Steveninck; J P Boegheim; Tom M A R Dubbelman
The influence of cupric ions on porphyrin-induced photodynamic membrane damage in human red blood cells.
Biochimica et biophysica acta 1985;821(1):1-7.