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Motonobu Anai
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52
Asano, Tomoichiro
47
Fukushima, Yasushi
43
Katagiri, Hideki
41
Inukai, Kouichi
39
Sakoda, Hideyuki
31
Ono, Hiraku
31
Kikuchi, Masatoshi
30
Oka, Yoshitaka
29
Fujishiro, Midori
28
Funaki, Masako
28
Ogihara, Toshio
25
Onishi, Yukiko
18
Ogihara, Takehide
18
Shojima, Nobuhiro
14
Yazaki, Yoshio
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All Publications
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2008: Koketsu Yuko; Sakoda Hideyuki; Fujishiro Midori; Kushiyama Akifumi; Fukushima Yasushi; Ono Hiraku; Anai Motonobu; Kikuchi Takako; Fukuda Takeshi; Kamata Hideaki; Horike Nanao; Uchijima Yasunobu; Kurihara Hiroki; Asano Tomoichiro
Hepatic overexpression of a dominant negative form of raptor enhances Akt phosphorylation and restores insulin sensitivity in K/KAy mice.
American journal of physiology. Endocrinology and metabolism 2008;294(4):E719-25.
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2008: Fujio Junko; Kushiyama Akifumi; Sakoda Hideyuki; Fujishiro Midori; Ogihara Takehide; Fukushima Yasushi; Anai Motonobu; Horike Nanao; Kamata Hideaki; Uchijima Yasunobu; Kurihara Hiroki; Asano Tomoichiro
Regulation of gut-derived resistin-like molecule beta expression by nutrients.
Diabetes research and clinical practice 2008;79(1):2-10.
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2007: Ono Hiraku; Sakoda Hideyuki; Fujishiro Midori; Anai Motonobu; Kushiyama Akifumi; Fukushima Yasushi; Katagiri Hideki; Ogihara Takehide; Oka Yoshitomo; Kamata Hideaki; Horike Nanao; Uchijima Yasunobu; Kurihara Hiroki; Asano Tomoichiro
Carboxy-terminal modulator protein induces Akt phosphorylation and activation, thereby enhancing antiapoptotic, glycogen synthetic, and glucose uptake pathways.
American journal of physiology. Cell physiology 2007;293(5):C1576-85.
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2006: Asano Tomoichiro; Sakosda Hideyuki; Fujishiro Midori; Anai Motonobu; Kushiyama Akifumi; Horike Nanao; Kamata Hideaki; Ogihara Takehide; Kurihara Hiroki; Uchijima Yasunobu
Physiological significance of resistin and resistin-like molecules in the inflammatory process and insulin resistance.
Current diabetes reviews 2006;2(4):449-54.
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2006: Viana Amelia Y I; Sakoda Hideyuki; Anai Motonobu; Fujishiro Midori; Ono Hiraku; Kushiyama Akifumi; Fukushima Yasushi; Sato Yuzo; Oshida Yoshiharu; Uchijima Yasunobu; Kurihara Hiroki; Asano Tomoichiro
Role of hepatic AMPK activation in glucose metabolism and dexamethasone-induced regulation of AMPK expression.
Diabetes research and clinical practice 2006;73(2):135-42.
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2005: Kushiyama Akifumi; Shojima Nobuhiro; Ogihara Takehide; Inukai Kouichi; Sakoda Hideyuki; Fujishiro Midori; Fukushima Yasushi; Anai Motonobu; Ono Hiraku; Horike Nanao; Viana Amelia Y I; Uchijima Yasunobu; Nishiyama Koichi; Shimosawa Tatsuo; Fujita Toshiro; Katagiri Hideki; Oka Yoshitomo; Kurihara Hiroki; Asano Tomoichiro
Resistin-like molecule beta activates MAPKs, suppresses insulin signaling in hepatocytes, and induces diabetes, hyperlipidemia, and fatty liver in transgenic mice on a high fat diet.
The Journal of biological chemistry 2005;280(51):42016-25.
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2005: Sakoda Hideyuki; Fujishiro Midori; Fujio Junko; Shojima Nobuhiro; Ogihara Takehide; Kushiyama Akifumi; Fukushima Yasushi; Anai Motonobu; Ono Hiraku; Kikuchi Masatoshi; Horike Nanao; Viana Amelia Y I; Uchijima Yasunobu; Kurihara Hiroki; Asano Tomoichiro
Glycogen debranching enzyme association with beta-subunit regulates AMP-activated protein kinase activity.
American journal of physiology. Endocrinology and metabolism 2005;289(3):E474-81.
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2005: Shojima N; Ogihara T; Inukai K; Fujishiro M; Sakoda H; Kushiyama A; Katagiri H; Anai M; Ono H; Fukushima Y; Horike N; Viana A Y I; Uchijima Y; Kurihara H; Asano T
Serum concentrations of resistin-like molecules beta and gamma are elevated in high-fat-fed and obese db/db mice, with increased production in the intestinal tract and bone marrow.
Diabetologia 2005;48(5):984-92.
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2005: Anai Motonobu; Shojima Nobuhiro; Katagiri Hideki; Ogihara Takehide; Sakoda Hideyuki; Onishi Yukiko; Ono Hiraku; Fujishiro Midori; Fukushima Yasushi; Horike Nanao; Viana Amelia; Kikuchi Masatoshi; Noguchi Noriko; Takahashi Shinichiro; Takata Kuniaki; Oka Yoshitomo; Uchijima Yasunobu; Kurihara Hiroki; Asano Tomoichiro
A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis.
The Journal of biological chemistry 2005;280(18):18525-35.
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2004: Asano Tomoichiro; Ogihara Takehide; Katagiri Hideki; Sakoda Hideyuki; Ono Hiraku; Fujishiro Midori; Anai Motonobu; Kurihara Hiroki; Uchijima Yasunobu
Glucose transporter and Na+/glucose cotransporter as molecular targets of anti-diabetic drugs.
Current medicinal chemistry 2004;11(20):2717-24.
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2004: Fukushima Yasushi; Matsui Toshimitsu; Saitoh Toshihito; Ichinose Masao; Tateishi Keisuke; Shindo Takayuki; Fujishiro Midori; Sakoda Hideyuki; Shojima Nobuhiro; Kushiyama Akifumi; Fukuda Satoru; Anai Motonobu; Ono Hiraku; Oka Masashi; Shimizu Yasuhito; Kurihara Hiroki; Nagai Ryozo; Ishikawa Takashi; Asano Tomoichiro; Omata Masao
Unique roles of G protein-coupled histamine H2 and gastrin receptors in growth and differentiation of gastric mucosa.
European journal of pharmacology 2004;502(3):243-52.
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2004: Ogihara T; Asano T; Katagiri H; Sakoda H; Anai M; Shojima N; Ono H; Fujishiro M; Kushiyama A; Fukushima Y; Kikuchi M; Noguchi N; Aburatani H; Gotoh Y; Komuro I; Fujita T
Oxidative stress induces insulin resistance by activating the nuclear factor-kappa B pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase.
Diabetologia 2004;47(5):794-805.
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2003: Ono Hiraku; Shimano Hitoshi; Katagiri Hideki; Yahagi Naoya; Sakoda Hideyuki; Onishi Yukiko; Anai Motonobu; Ogihara Takehide; Fujishiro Midori; Viana Amelia Y I; Fukushima Yasushi; Abe Miho; Shojima Nobuhiro; Kikuchi Masatoshi; Yamada Nobuhiro; Oka Yoshitomo; Asano Tomoichiro
Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement.
Diabetes 2003;52(12):2905-13.
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2003: Sakoda Hideyuki; Gotoh Yukiko; Katagiri Hideki; Kurokawa Mineo; Ono Hiraku; Onishi Yukiko; Anai Motonobu; Ogihara Takehide; Fujishiro Midori; Fukushima Yasushi; Abe Miho; Shojima Nobuhiro; Kikuchi Masatoshi; Oka Yoshitomo; Hirai Hisamaru; Asano Tomoichiro
Differing roles of Akt and serum- and glucocorticoid-regulated kinase in glucose metabolism, DNA synthesis, and oncogenic activity.
The Journal of biological chemistry 2003;278(28):25802-7.
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2003: Fukushima Yasushi; Shindo Takayuki; Anai Motonobu; Saitoh Toshihito; Wang Yuhui; Fujishiro Midori; Ohashi Yoshio; Ogihara Takehide; Inukai Kouichi; Ono Hiraku; Sakoda Hideyuki; Kurihara Yukiko; Honda Miho; Shojima Nobuhiro; Fukushima Harumi; Haraikawa-Onishi Yukiko; Katagiri Hideki; Shimizu Yasuhito; Ichinose Masao; Ishikawa Takashi; Omata Masao; Nagai Ryozo; Kurihara Hiroki; Asano Tomoichiro
Structural and functional characterization of gastric mucosa and central nervous system in histamine H2 receptor-null mice.
European journal of pharmacology 2003;468(1):47-58.
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2003: Onishi Yukiko; Honda Miho; Ogihara Takehide; Sakoda Hideyuki; Anai Motonobu; Fujishiro Midori; Ono Hiraku; Shojima Nobuhiro; Fukushima Yasushi; Inukai Kouichi; Katagiri Hideki; Kikuchi Masatoshi; Oka Yoshitomo; Asano Tomoichiro
Ethanol feeding induces insulin resistance with enhanced PI 3-kinase activation.
Biochemical and biophysical research communications 2003;303(3):788-94.
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2003: Fujishiro Midori; Gotoh Yukiko; Katagiri Hideki; Sakoda Hideyuki; Ogihara Takehide; Anai Motonobu; Onishi Yukiko; Ono Hiraku; Abe Miho; Shojima Nobuhiro; Fukushima Yasushi; Kikuchi Masatoshi; Oka Yoshitomo; Asano Tomoichiro
Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes.
Molecular endocrinology (Baltimore, Md.) 2003;17(3):487-97.
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2003: Fukushima Yasushi; Ishikawa Takashi; Saitoh Toshihito; Tateishi Keisuke; Ogihara Takehide; Fujishiro Midori; Shojima Nobuhiro; Honda Miho; Kushiyama Akifumi; Anai Motonobu; Sakoda Hideyuki; Ono Hiraku; Onishi Yukiko; Otsuka Hiroko; Katagiri Hideki; Nagai Ryozo; Omata Masao; Asano Tomoichiro
Extremely early onset of ranitidine action on human histamine H2 receptors expressed in HEK293 cells.
Digestion 2003;68(2-3):145-52.
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2002: Ogihara Takehide; Asano Tomoichiro; Ando Katsuyuki; Chiba Yuko; Sakoda Hideyuki; Anai Motonobu; Shojima Nobuhiro; Ono Hiraku; Onishi Yukiko; Fujishiro Midori; Katagiri Hideki; Fukushima Yasushi; Kikuchi Masatoshi; Noguchi Noriko; Aburatani Hiroyuki; Komuro Issei; Fujita Toshiro
Angiotensin II-induced insulin resistance is associated with enhanced insulin signaling.
Hypertension 2002;40(6):872-9.
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2002: Song Haiyan; Shojima Nobuhiro; Sakoda Hideyuki; Ogihara Takehide; Fujishiro Midori; Katagiri Hideki; Anai Motonobu; Onishi Yukiko; Ono Hiraku; Inukai Kouichi; Fukushima Yasushi; Kikuchi Masatoshi; Shimano Hitoshi; Yamada Nobuhiro; Oka Yoshitomo; Asano Tomoichiro
Resistin is regulated by C/EBPs, PPARs, and signal-transducing molecules.
Biochemical and biophysical research communications 2002;299(2):291-8.
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2002: Ogihara Takehide; Asano Tomoichiro; Ando Katsuyuki; Sakoda Hideyuki; Anai Motonobu; Shojima Nobuhiro; Ono Hiraku; Onishi Yukiko; Fujishiro Midori; Abe Miho; Fukushima Yasushi; Kikuchi Masatoshi; Fujita Toshiro
High-salt diet enhances insulin signaling and induces insulin resistance in Dahl salt-sensitive rats.
Hypertension 2002;40(1):83-9.
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2002: Shojima Nobuhiro; Sakoda Hideyuki; Ogihara Takehide; Fujishiro Midori; Katagiri Hideki; Anai Motonobu; Onishi Yukiko; Ono Hiraku; Inukai Kouichi; Abe Miho; Fukushima Yasushi; Kikuchi Masatoshi; Oka Yoshitomo; Asano Tomoichiro
Humoral regulation of resistin expression in 3T3-L1 and mouse adipose cells.
Diabetes 2002;51(6):1737-44.
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2002: Sakoda Hideyuki; Ogihara Takehide; Anai Motonobu; Fujishiro Midori; Ono Hiraku; Onishi Yukiko; Katagiri Hideki; Abe Miho; Fukushima Yasushi; Shojima Nobuhiro; Inukai Kouichi; Kikuchi Masatoshi; Oka Yoshitomo; Asano Tomoichiro
Activation of AMPK is essential for AICAR-induced glucose uptake by skeletal muscle but not adipocytes.
American journal of physiology. Endocrinology and metabolism 2002;282(6):E1239-44.
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2001: Onishi-Haraikawa Y; Funaki M; Gotoh N; Shibuya M; Inukai K; Katagiri H; Fukushima Y; Anai M; Ogihara T; Sakoda H; Ono H; Kikuchi M; Oka Y; Asano T
Unique phosphorylation mechanism of Gab1 using PI 3-kinase as an adaptor protein.
Biochemical and biophysical research communications 2001;288(2):476-82.
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2001: Ono H; Katagiri H; Funaki M; Anai M; Inukai K; Fukushima Y; Sakoda H; Ogihara T; Onishi Y; Fujishiro M; Kikuchi M; Oka Y; Asano T
Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes.
Molecular endocrinology (Baltimore, Md.) 2001;15(8):1411-22.
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2001: Fukushima Y; Saitoh T; Anai M; Ogihara T; Inukai K; Funaki M; Sakoda H; Onishi Y; Ono H; Fujishiro M; Ishikawa T; Takata K; Nagai R; Omata M; Asano T
Palmitoylation of the canine histamine H2 receptor occurs at Cys(305) and is important for cell surface targeting.
Biochimica et biophysica acta 2001;1539(3):181-91.
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2001: Fujishiro M; Gotoh Y; Katagiri H; Sakoda H; Ogihara T; Anai M; Onishi Y; Ono H; Funaki M; Inukai K; Fukushima Y; Kikuchi M; Oka Y; Asano T
MKK6/3 and p38 MAPK pathway activation is not necessary for insulin-induced glucose uptake but regulates glucose transporter expression.
The Journal of biological chemistry 2001;276(23):19800-6.
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2001: Oku A; Nawano M; Ueta K; Fujita T; Umebayashi I; Arakawa K; Kano-Ishihara T; Saito A; Anai M; Funaki M; Kikuchi M; Oka Y; Asano T
Inhibitory effect of hyperglycemia on insulin-induced Akt/protein kinase B activation in skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2001;280(5):E816-24.
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2001: Ogihara T; Asano T; Ando K; Chiba Y; Sekine N; Sakoda H; Anai M; Onishi Y; Fujishiro M; Ono H; Shojima N; Inukai K; Fukushima Y; Kikuchi M; Fujita T
Insulin resistance with enhanced insulin signaling in high-salt diet-fed rats.
Diabetes 2001;50(3):573-83.
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2001: Inukai K; Funaki M; Anai M; Ogihara T; Katagiri H; Fukushima Y; Sakoda H; Onishi Y; Ono H; Fujishiro M; Abe M; Oka Y; Kikuchi M; Asano T
Five isoforms of the phosphatidylinositol 3-kinase regulatory subunit exhibit different associations with receptor tyrosine kinases and their tyrosine phosphorylations.
FEBS letters 2001;490(1-2):32-8.
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2001: Fukushima Y; Saitoh T; Anai M; Tsukuda K; Onishi Y; Sakoda H; Inukai K; Ogihara T; Funaki M; Ono H; Fujishiro M; Ishikawa T; Nagai R; Omata M; Asano T
G649, an allelic variant of the human H2 receptor with low basal activity, is resistant to upregulation upon antagonist exposure.
The pharmacogenomics journal 2001;1(1):78-83.
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2001: Fukushima Y; Otsuka H; Ishikawa M; Asano T; Anai M; Katsube T; Ogawa K; Kajiwara T; Ohkawa S; Ishikawa T; Omata M; Saitoh T
Potent and long-lasting action of lafutidine on the human histamine H(2) receptor.
Digestion 2001;64(3):155-60.
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2000: Sakoda H; Ogihara T; Anai M; Funaki M; Inukai K; Katagiri H; Fukushima Y; Onishi Y; Ono H; Fujishiro M; Kikuchi M; Oka Y; Asano T
Dexamethasone-induced insulin resistance in 3T3-L1 adipocytes is due to inhibition of glucose transport rather than insulin signal transduction.
Diabetes 2000;49(10):1700-8.
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2000: Asano T; Kanda A; Katagiri H; Nawano M; Ogihara T; Inukai K; Anai M; Fukushima Y; Yazaki Y; Kikuchi M; Hooshmand-Rad R; Heldin C H; Oka Y; Funaki M
p110beta is up-regulated during differentiation of 3T3-L1 cells and contributes to the highly insulin-responsive glucose transport activity.
The Journal of biological chemistry 2000;275(23):17671-6.
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2000: Oku A; Ueta K; Nawano M; Arakawa K; Kano-Ishihara T; Matsumoto M; Saito A; Tsujihara K; Anai M; Asano T
Antidiabetic effect of T-1095, an inhibitor of Na(+)-glucose cotransporter, in neonatally streptozotocin-treated rats.
European journal of pharmacology 2000;391(1-2):183-92.
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2000: Nawano M; Oku A; Ueta K; Umebayashi I; Ishirahara T; Arakawa K; Saito A; Anai M; Kikuchi M; Asano T
Hyperglycemia contributes insulin resistance in hepatic and adipose tissue but not skeletal muscle of ZDF rats.
American journal of physiology. Endocrinology and metabolism 2000;278(3):E535-43.
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2000: Inukai K; Funaki M; Nawano M; Katagiri H; Ogihara T; Anai M; Onishi Y; Sakoda H; Ono H; Fukushima Y; Kikuchi M; Oka Y; Asano T
The N-terminal 34 residues of the 55 kDa regulatory subunits of phosphoinositide 3-kinase interact with tubulin.
The Biochemical journal 2000;346 Pt 2():483-9.
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1999: Asano T; Tsukuda K; Katagiri H; Onishi Y; Sakoda H; Ono H; Ogihara T; Funaki M; Anai M; Inukai K; Fujishiro M; Fukushima Y; Yamasoba T; Oka T; Kikuchi M; Oka Y
Clinical relevance of heteroplasmic concentration of mitochondrial A3243G mutation in leucocytes.
Diabetologia 1999;42(12):1439-40.
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1999: Nawano M; Ueta K; Oku A; Arakawa K; Saito A; Funaki M; Anai M; Kikuchi M; Oka Y; Asano T
Hyperglycemia impairs the insulin signaling step between PI 3-kinase and Akt/PKB activations in ZDF rat liver.
Biochemical and biophysical research communications 1999;266(1):252-6.
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1999: Fukushima Y; Ohmachi Y; Asano T; Nawano M; Funaki M; Anai M; Ogihara T; Inukai K; Onishi Y; Sakoda H; Saitoh T; Matsuhashi N; Yazaki Y; Sugano K
Localization of the histamine H(2) receptor, a target for antiulcer drugs, in gastric parietal cells.
Digestion 1999;60(6):522-7.
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1999: Nawano M; Anai M; Funaki M; Kobayashi H; Kanda A; Fukushima Y; Inukai K; Ogihara T; Sakoda H; Onishi Y; Kikuchi M; Yazaki Y; Oka Y; Asano T
Imidapril, an angiotensin-converting enzyme inhibitor, improves insulin sensitivity by enhancing signal transduction via insulin receptor substrate proteins and improving vascular resistance in the Zucker fatty rat.
Metabolism: clinical and experimental 1999;48(10):1248-55.
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1999: Oku A; Ueta K; Arakawa K; Ishihara T; Nawano M; Kuronuma Y; Matsumoto M; Saito A; Tsujihara K; Anai M; Asano T; Kanai Y; Endou H
T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes.
Diabetes 1999;48(9):1794-800.
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1999: Funaki M; Katagiri H; Kanda A; Anai M; Nawano M; Ogihara T; Inukai K; Fukushima Y; Ono H; Yazaki Y; Kikuchi M; Oka Y; Asano T
p85/p110-type phosphatidylinositol kinase phosphorylates not only the D-3, but also the D-4 position of the inositol ring.
The Journal of biological chemistry 1999;274(31):22019-24.
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1999: Sakoda H; Ogihara T; Anai M; Funaki M; Inukai K; Katagiri H; Fukushima Y; Onishi Y; Ono H; Yazaki Y; Kikuchi M; Oka Y; Asano T
No correlation of plasma cell 1 overexpression with insulin resistance in diabetic rats and 3T3-L1 adipocytes.
Diabetes 1999;48(7):1365-71.
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1999: Anai M; Funaki M; Ogihara T; Kanda A; Onishi Y; Sakoda H; Inukai K; Nawano M; Fukushima Y; Yazaki Y; Kikuchi M; Oka Y; Asano T
Enhanced insulin-stimulated activation of phosphatidylinositol 3-kinase in the liver of high-fat-fed rats.
Diabetes 1999;48(1):158-69.
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1998: Anai M; Ono H; Funaki M; Fukushima Y; Inukai K; Ogihara T; Sakoda H; Onishi Y; Yazaki Y; Kikuchi M; Oka Y; Asano T
Different subcellular distribution and regulation of expression of insulin receptor substrate (IRS)-3 from those of IRS-1 and IRS-2.
The Journal of biological chemistry 1998;273(45):29686-92.
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1998: Shin B C; Suzuki M; Inukai K; Anai M; Asano T; Takata K
Multiple isoforms of the regulatory subunit for phosphatidylinositol 3-kinase (PI3-kinase) are expressed in neurons in the rat brain.
Biochemical and biophysical research communications 1998;246(2):313-9.
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1998: Terasaki J; Anai M; Funaki M; Shibata T; Inukai K; Ogihara T; Ishihara H; Katagiri H; Onishi Y; Sakoda H; Fukushima Y; Yazaki Y; Kikuchi M; Oka Y; Asano T
Role of JTT-501, a new insulin sensitiser, in restoring impaired GLUT4 translocation in adipocytes of rats fed a high fat diet.
Diabetologia 1998;41(4):400-9.
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1998: Anai M; Funaki M; Ogihara T; Terasaki J; Inukai K; Katagiri H; Fukushima Y; Yazaki Y; Kikuchi M; Oka Y; Asano T
Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats.
Diabetes 1998;47(1):13-23.
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1997: Ogihara T; Isobe T; Ichimura T; Taoka M; Funaki M; Sakoda H; Onishi Y; Inukai K; Anai M; Fukushima Y; Kikuchi M; Yazaki Y; Oka Y; Asano T
14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain.
The Journal of biological chemistry 1997;272(40):25267-74.
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1997: Fukushima Y; Asano T; Takata K; Funaki M; Ogihara T; Anai M; Tsukuda K; Saitoh T; Katagiri H; Aihara M; Matsuhashi N; Oka Y; Yazaki Y; Sugano K
Role of the C terminus in histamine H2 receptor signaling, desensitization, and agonist-induced internalization.
The Journal of biological chemistry 1997;272(31):19464-70.
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1997: Fukushima Y; Asano T; Saitoh T; Anai M; Funaki M; Ogihara T; Katagiri H; Matsuhashi N; Yazaki Y; Sugano K
Oligomer formation of histamine H2 receptors expressed in Sf9 and COS7 cells.
FEBS letters 1997;409(2):283-6.
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1997: Ogihara T; Shin B C; Anai M; Katagiri H; Inukai K; Funaki M; Fukushima Y; Ishihara H; Takata K; Kikuchi M; Yazaki Y; Oka Y; Asano T
Insulin receptor substrate (IRS)-2 is dephosphorylated more rapidly than IRS-1 via its association with phosphatidylinositol 3-kinase in skeletal muscle cells.
The Journal of biological chemistry 1997;272(19):12868-73.
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1997: Inukai K; Funaki M; Ogihara T; Katagiri H; Kanda A; Anai M; Fukushima Y; Hosaka T; Suzuki M; Shin B C; Takata K; Yazaki Y; Kikuchi M; Oka Y; Asano T
p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin.
The Journal of biological chemistry 1997;272(12):7873-82.
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1996: Fukushima Y; Asano T; Katagiri H; Aihara M; Saitoh T; Anai M; Funaki M; Ogihara T; Inukai K; Matsuhashi N; Oka Y; Yazaki Y; Sugano K
Interaction between the two signal transduction systems of the histamine H2 receptor: desensitizing and sensitizing effects of histamine stimulation on histamine-dependent cAMP production in Chinese hamster ovary cells.
The Biochemical journal 1996;320 ( Pt 1)():27-32.
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1996: Inukai K; Anai M; Van Breda E; Hosaka T; Katagiri H; Funaki M; Fukushima Y; Ogihara T; Yazaki Y; Kikuchi; Oka Y; Asano T
A novel 55-kDa regulatory subunit for phosphatidylinositol 3-kinase structurally similar to p55PIK Is generated by alternative splicing of the p85alpha gene.
The Journal of biological chemistry 1996;271(10):5317-20.
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1995: Inukai K; Katagiri H; Takata K; Asano T; Anai M; Ishihara H; Nakazaki M; Kikuchi M; Yazaki Y; Oka Y
Characterization of rat GLUT5 and functional analysis of chimeric proteins of GLUT1 glucose transporter and GLUT5 fructose transporter.
Endocrinology 1995;136(11):4850-7.
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1995: Ishihara H; Asano T; Tsukuda K; Katagiri H; Inukai K; Anai M; Yazaki Y; Miyazaki J; Kikuchi M; Oka Y
Human GLUT-2 overexpression does not affect glucose-stimulated insulin secretion in MIN6 cells.
The American journal of physiology 1995;269(5 Pt 1):E897-902.
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1995: Katagiri H; Terasaki J; Murata T; Ishihara H; Ogihara T; Inukai K; Fukushima Y; Anai M; Kikuchi M; Miyazaki J
A novel isoform of syntaxin-binding protein homologous to yeast Sec1 expressed ubiquitously in mammalian cells.
The Journal of biological chemistry 1995;270(10):4963-6.
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1994: Anai M; Oka Y
[Human glucokinase gene and analysis of its promoter region]
Nippon rinsho. Japanese journal of clinical medicine 1994;52(10):2572-6.
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1994: Inukai K; Asano T; Katagiri H; Anai M; Funaki M; Ishihara H; Tsukuda K; Kikuchi M; Yazaki Y; Oka Y
Replacement of both tryptophan residues at 388 and 412 completely abolished cytochalasin B photolabelling of the GLUT1 glucose transporter.
The Biochemical journal 1994;302 ( Pt 2)():355-61.
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1994: Katagiri H; Asano T; Ishihara H; Inukai K; Anai M; Yamanouchi T; Tsukuda K; Kikuchi M; Kitaoka H; Ohsawa N
Mitochondrial diabetes mellitus: prevalence and clinical characterization of diabetes due to mitochondrial tRNA(Leu(UUR)) gene mutation in Japanese patients.
Diabetologia 1994;37(5):504-10.
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1994: Ishihara H; Asano T; Tsukuda K; Katagiri H; Inukai K; Anai M; Kikuchi M; Yazaki Y; Miyazaki J; Oka Y
Overexpression of hexokinase I but not GLUT1 glucose transporter alters concentration dependence of glucose-stimulated insulin secretion in pancreatic beta-cell line MIN6.
The Journal of biological chemistry 1994;269(4):3081-7.
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1993: Inukai K; Asano T; Katagiri H; Ishihara H; Anai M; Fukushima Y; Tsukuda K; Kikuchi M; Yazaki Y; Oka Y
Cloning and increased expression with fructose feeding of rat jejunal GLUT5.
Endocrinology 1993;133(5):2009-14.
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1993: Ishihara H; Asano T; Tsukuda K; Katagiri H; Inukai K; Anai M; Kikuchi M; Yazaki Y; Miyazaki J I; Oka Y
Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets.
Diabetologia 1993;36(11):1139-45.
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1993: Asano T; Takata K; Katagiri H; Ishihara H; Inukai K; Anai M; Hirano H; Yazaki Y; Oka Y
The role of N-glycosylation in the targeting and stability of GLUT1 glucose transporter.
FEBS letters 1993;324(3):258-61.
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1992: Katagiri H; Asano T; Ishihara H; Inukai K; Anai M; Miyazaki J; Tsukuda K; Kikuchi M; Yazaki Y; Oka Y
Nonsense mutation of glucokinase gene in late-onset non-insulin-dependent diabetes mellitus.
Lancet 1992;340(8831):1316-7.
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