Steven Dubinett

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Yanagawa Jane; Walser Tonya C; Zhu Li X; Hong Longsheng; Fishbein Michael C; Mah Vei; Chia David; Goodglick Lee; Elashoff David A; Luo Jie; Magyar Clara E; Dohadwala Mariam; Lee Jay M; St John Maie A; Strieter Robert M; Sharma Sherven; Dubinett Steven M
Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma.
Garon Edward B; Dubinett Steven M
Intracellular signaling molecules.
St John Maie A; Dohadwala Mariam; Luo Jie; Wang Guanyu; Lee Gina; Shih Hubert; Heinrich Eileen; Krysan Kostantyn; Walser Tonya; Hazra Saswati; Zhu Li; Lai Chi; Abemayor Elliot; Fishbein Michael; Elashoff David A; Sharma Sherven; Dubinett Steven M
Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma.

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All Publications

2009: Yanagawa Jane; Walser Tonya C; Zhu Li X; Hong Longsheng; Fishbein Michael C; Mah Vei; Chia David; Goodglick Lee; Elashoff David A; Luo Jie; Magyar Clara E; Dohadwala Mariam; Lee Jay M; St John Maie A; Strieter Robert M; Sharma Sherven; Dubinett Steven M
Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(22):6820-9.
2009: Garon Edward B; Dubinett Steven M
Intracellular signaling molecules.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2009;4(11 Suppl 3):S1057-8.
2009: St John Maie A; Dohadwala Mariam; Luo Jie; Wang Guanyu; Lee Gina; Shih Hubert; Heinrich Eileen; Krysan Kostantyn; Walser Tonya; Hazra Saswati; Zhu Li; Lai Chi; Abemayor Elliot; Fishbein Michael; Elashoff David A; Sharma Sherven; Dubinett Steven M
Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(19):6018-27.
2009: Limsukon Atikun; Susanto Irawan; Hoo Guy W Soo; Dubinett Steven M; Batra Raj K
Regression of recurrent respiratory papillomatosis with celecoxib and erlotinib combination therapy.
Chest 2009;136(3):924-6.
2009: Lee Gina; Walser Tonya C; Dubinett Steven M
Chronic inflammation, chronic obstructive pulmonary disease, and lung cancer.
Current opinion in pulmonary medicine 2009;15(4):303-7.
2009: Andersson Asa; Yang Seok-Chul; Huang Min; Zhu Li; Kar Upendra K; Batra Raj K; Elashoff David; Strieter Robert M; Dubinett Steven M; Sharma Sherven
IL-7 promotes CXCR3 ligand-dependent T cell antitumor reactivity in lung cancer.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(11):6951-8.
2009: Punturieri Antonello; Szabo Eva; Croxton Thomas L; Shapiro Steven D; Dubinett Steven M
Lung cancer and chronic obstructive pulmonary disease: needs and opportunities for integrated research.
Journal of the National Cancer Institute 2009;101(8):554-9.
2009: Lu Qing-Yi; Yang Yanan; Jin Yu Sheng; Zhang Zuo-Feng; Heber David; Li Frederick P; Dubinett Steven M; Sondej Melissa A; Loo Joseph A; Rao Jian Yu
Effects of green tea extract on lung cancer A549 cells: proteomic identification of proteins associated with cell migration.
Proteomics 2009;9(3):757-67.
2009: Reckamp Karen L; Figlin Robert A; Burdick Marie D; Dubinett Steven M; Elashoff Robert M; Strieter Robert M
CXCR4 expression on circulating pan-cytokeratin positive cells is associated with survival in patients with advanced non-small cell lung cancer.
BMC cancer 2009;9():213.
2008: Walser Tonya; Cui Xiaoyan; Yanagawa Jane; Lee Jay M; Heinrich Eileen; Lee Gina; Sharma Sherven; Dubinett Steven M
Smoking and lung cancer: the role of inflammation.
Proceedings of the American Thoracic Society 2008;5(8):811-5.
2008: Dubinett Steven M; Aberle Denise R; Tashkin Donald P; Mao Jenny T
The partners--airflow obstruction, emphysema, and lung cancer.
American journal of respiratory and critical care medicine 2008;178(7):665-6.
2008: Dubinett Steven M; Mao Jenny T; Hazra Saswati
Focusing downstream in lung cancer prevention: 15-hydroxyprostaglandin dehydrogenase.
Cancer prevention research (Philadelphia, Pa.) 2008;1(4):223-5.
2008: Lee Jay M; Yanagawa Jane; Peebles Katherine A; Sharma Sherven; Mao Jenny T; Dubinett Steven M
Inflammation in lung carcinogenesis: new targets for lung cancer chemoprevention and treatment.
Critical reviews in oncology/hematology 2008;66(3):208-17.
2008: Su Helen; Seimbille Yann; Ferl Gregory Z; Bodenstein Claudia; Fueger Barbara; Kim Kevin J; Hsu Yu-Tien; Dubinett Steven M; Phelps Michael E; Czernin Johannes; Weber Wolfgang A
Evaluation of [(18)F]gefitinib as a molecular imaging probe for the assessment of the epidermal growth factor receptor status in malignant tumors.
European journal of nuclear medicine and molecular imaging 2008;35(6):1089-99.
2008: Einhorn Lawrence H; Bonomi Philip; Bunn Paul A; Camidge D Ross; Carbone David Paul; Choy Hak; Dubinett Steven M; Gandara David R; Gaspar Laurie E; Govindan Ramaswamy; Johnson David H; Minna John D; Scagliotti Giorgio; West Howard J; Herbst Roy S
Summary report 7th Annual Targeted Therapies of the Treatment of Lung Cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008;3(5):545-55.
2008: Reckamp Karen L; Gardner Brian K; Figlin Robert A; Elashoff David; Krysan Kostyantyn; Dohadwala Mariam; Mao Jenny; Sharma Sherven; Inge Landon; Rajasekaran Ayyappan; Dubinett Steven M
Tumor response to combination celecoxib and erlotinib therapy in non-small cell lung cancer is associated with a low baseline matrix metalloproteinase-9 and a decline in serum-soluble E-cadherin.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008;3(2):117-24.
2008: Krysan Kostyantyn; Lee Jay M; Dohadwala Mariam; Gardner Brian K; Reckamp Karen L; Garon Edward; St John Maie; Sharma Sherven; Dubinett Steven M
Inflammation, epithelial to mesenchymal transition, and epidermal growth factor receptor tyrosine kinase inhibitor resistance.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008;3(2):107-10.
2008: Hazra Saswati; Peebles Katherine A; Sharma Sherven; Mao Jenny T; Dubinett Steven M
The Role of PPARgamma in the Cyclooxygenase Pathway in Lung Cancer.
PPAR research 2008;2008():790568.
2008: Baratelli Felicita; Takedatsu Hiroko; Hazra Saswati; Peebles Katherine; Luo Jie; Kurimoto Pam S; Zeng Gang; Batra Raj K; Sharma Sherven; Dubinett Steven M; Lee Jay M
Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in non-small cell lung cancer.
Journal of translational medicine 2008;6():38.
2007: Liu Ming; Yang Seok-Chul; Sharma Sherven; Luo Jie; Cui Xiaoyan; Peebles Katherine A; Huang Min; Sato Mitsuo; Ramirez Ruben D; Shay Jerry W; Minna John D; Dubinett Steven M
EGFR signaling is required for TGF-beta 1 mediated COX-2 induction in human bronchial epithelial cells.
American journal of respiratory cell and molecular biology 2007;37(5):578-88.
2007: Peebles Katherine A; Lee Jay M; Mao Jenny T; Hazra Saswati; Reckamp Karen L; Krysan Kostyantyn; Dohadwala Mariam; Heinrich Eileen L; Walser Tonya C; Cui Xiaoyan; Baratelli Felicita E; Garon Edward; Sharma Sherven; Dubinett Steven M
Inflammation and lung carcinogenesis: applying findings in prevention and treatment.
Expert review of anticancer therapy 2007;7(10):1405-21.
2007: Hazra Saswati; Dubinett Steven M
Ciglitazone mediates COX-2 dependent suppression of PGE2 in human non-small cell lung cancer cells.
Prostaglandins, leukotrienes, and essential fatty acids 2007;77(1):51-8.
2007: Hazra Saswati; Batra Raj K; Tai Hsin H; Sharma Sherven; Cui Xiaoyan; Dubinett Steven M
Pioglitazone and rosiglitazone decrease prostaglandin E2 in non-small-cell lung cancer cells by up-regulating 15-hydroxyprostaglandin dehydrogenase.
Molecular pharmacology 2007;71(6):1715-20.
2007: Cui X; Zhang L; Luo J; Rajasekaran A; Hazra S; Cacalano N; Dubinett S M
Unphosphorylated STAT6 contributes to constitutive cyclooxygenase-2 expression in human non-small cell lung cancer.
Oncogene 2007;26(29):4253-60.
2007: Lu Qing-Yi; Jin Yu Sheng; Zhang Zuo-Feng; Le Anh D; Heber David; Li Frederick P; Dubinett Steven M; Rao Jian Yu
Green tea induces annexin-I expression in human lung adenocarcinoma A549 cells: involvement of annexin-I in actin remodeling.
Laboratory investigation; a journal of technical methods and pathology 2007;87(5):456-65.
2007: Lee Jay M; Mao Jenny T; Krysan Kostyantyn; Dubinett Steven M
Significance of cyclooxygenase-2 in prognosis, targeted therapy and chemoprevention of NSCLC.
Future oncology (London, England) 2007;3(2):149-53.
2006: Su Helen; Bodenstein Claudia; Dumont Rebecca A; Seimbille Yann; Dubinett Steven; Phelps Michael E; Herschman Harvey; Czernin Johannes; Weber Wolfgang
Monitoring tumor glucose utilization by positron emission tomography for the prediction of treatment response to epidermal growth factor receptor kinase inhibitors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(19):5659-67.
2006: Feeley Brian T; Liu Nancy Q; Conduah Augustine H; Krenek Lucie; Roth Kevin; Dougall William C; Huard Johnny; Dubinett Steve; Lieberman Jay R
Mixed metastatic lung cancer lesions in bone are inhibited by noggin overexpression and Rank:Fc administration.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(10):1571-80.
2006: Zeng Gang; Aldridge Michael E; Tian Xiaoli; Seiler Daniel; Zhang Xiaolong; Jin Yusheng; Rao Jianyu; Li Weidong; Chen Dequan; Langford Marlyn P; Duggan Chris; Belldegrun Arie S; Dubinett Steven M
Dendritic cell surface calreticulin is a receptor for NY-ESO-1: direct interactions between tumor-associated antigen and the innate immune system.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):3582-9.
2006: Reckamp Karen L; Krysan Kostyantyn; Morrow Jason D; Milne Ginger L; Newman Robert A; Tucker Christopher; Elashoff Robert M; Dubinett Steven M; Figlin Robert A
A phase I trial to determine the optimal biological dose of celecoxib when combined with erlotinib in advanced non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(11 Pt 1):3381-8.
2006: Hoang Bao; Zhu Li; Shi Yijiang; Frost Patrick; Yan Huajun; Sharma Sanjai; Sharma Sherven; Goodglick Lee; Dubinett Steven; Lichtenstein Alan
Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance.
Blood 2006;107(11):4484-90.
2006: Krysan Kostyantyn; Reckamp Karen L; Sharma Sherven; Dubinett Steven M
The potential and rationale for COX-2 inhibitors in lung cancer.
Anti-cancer agents in medicinal chemistry 2006;6(3):209-20.
2006: Dohadwala Mariam; Yang Seok-Chul; Luo Jie; Sharma Sherven; Batra Raj K; Huang Min; Lin Ying; Goodglick Lee; Krysan Kostyantyn; Fishbein Michael C; Hong Longsheng; Lai Chi; Cameron Robert B; Gemmill Robert M; Drabkin Harry A; Dubinett Steven M
Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer.
Cancer research 2006;66(10):5338-45.
2006: Cui Xiaoyan; Yang Seok-Chul; Sharma Sherven; Heuze-Vourc'h Nathalie; Dubinett Steven M
IL-4 regulates COX-2 and PGE2 production in human non-small cell lung cancer.
Biochemical and biophysical research communications 2006;343(4):995-1001.
2006: Yang Seok-Chul; Batra Raj K; Hillinger Sven; Reckamp Karen L; Strieter Robert M; Dubinett Steven M; Sharma Sherven
Intrapulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
Cancer research 2006;66(6):3205-13.
2006: Pan Judong; Burdick Marie D; Belperio John A; Xue Ying Ying; Gerard Craig; Sharma Sherven; Dubinett Steven M; Strieter Robert M
CXCR3/CXCR3 ligand biological axis impairs RENCA tumor growth by a mechanism of immunoangiostasis.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(3):1456-64.
2006: Liu Wei; Dubinett Steven; Patterson Simie Lavern A; Kelly Kathleen A
COX-2 inhibition affects growth rate of Chlamydia muridarum within epithelial cells.
Microbes and infection / Institut Pasteur 2006;8(2):478-86.
2006: Mao Jenny T; Fishbein Michael C; Adams Bradley; Roth Michael D; Goodglick Lee; Hong Longsheng; Burdick Marie; Strieter E Robert M; Holmes Carmack; Tashkin Donald P; Dubinett Steven M
Celecoxib decreases Ki-67 proliferative index in active smokers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(1):314-20.
2006: Zhang L; Sharma S; Hershman J M; Brent G A; Dubinett S M; Huang M
Iodide sensitizes genetically modified non-small cell lung cancer cells to ionizing radiation.
Cancer gene therapy 2006;13(1):74-81.
2005: Weinberg Olga K; Marquez-Garban Diana C; Fishbein Michael C; Goodglick Lee; Garban Hermes J; Dubinett Steven M; Pietras Richard J
Aromatase inhibitors in human lung cancer therapy.
Cancer research 2005;65(24):11287-91.
2005: Dalwadi Harnisha; Krysan Kostyantyn; Heuze-Vourc'h Nathalie; Dohadwala Mariam; Elashoff David; Sharma Sherven; Cacalano Nicholas; Lichtenstein Alan; Dubinett Steven
Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7674-82.
2005: Rodriguez Paulo C; Hernandez Claudia P; Quiceno David; Dubinett Steven M; Zabaleta Jovanny; Ochoa Juan B; Gilbert Jill; Ochoa Augusto C
Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma.
The Journal of experimental medicine 2005;202(7):931-9.
2005: Baratelli Felicita; Lin Ying; Zhu Li; Yang Seok-Chul; Heuzé-Vourc'h Nathalie; Zeng Gang; Reckamp Karen; Dohadwala Mariam; Sharma Sherven; Dubinett Steven M
Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1483-90.
2005: Baratelli Felicita; Krysan Kostyantyn; Heuzé-Vourc'h Nathalie; Zhu Li; Escuadro Brian; Sharma Sherven; Reckamp Karen; Dohadwala Mariam; Dubinett Steven M
PGE2 confers survivin-dependent apoptosis resistance in human monocyte-derived dendritic cells.
Journal of leukocyte biology 2005;78(2):555-64.
2005: Mao Jenny T; Cui Xiaoyan; Reckamp Karen; Liu Ming; Krysan Kostyantyn; Dalwadi Harnisha; Sharma Sherven; Hazra Saswati; Strieter Robert; Gardner Brian; Dubinett Steven M
Chemoprevention strategies with cyclooxygenase-2 inhibitors for lung cancer.
Clinical lung cancer 2005;7(1):30-9.
2005: Krysan Kostyantyn; Reckamp Karen L; Dalwadi Harnisha; Sharma Sherven; Rozengurt Enrique; Dohadwala Mariam; Dubinett Steven M
Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner.
Cancer research 2005;65(14):6275-81.
2005: Sharma Sherven; Zhu Li; Yang Seok Chul; Zhang Ling; Lin Jeff; Hillinger Sven; Gardner Brian; Reckamp Karen; Strieter Robert M; Huang Min; Batra Raj K; Dubinett Steven M
Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):813-9.
2005: Heuzé-Vourc'h Nathalie; Liu Ming; Dalwadi Harnisha; Baratelli Felicita E; Zhu Li; Goodglick Lee; Põld Mehis; Sharma Sherven; Ramirez Ruben D; Shay Jerry W; Minna John D; Strieter Robert M; Dubinett Steven M
IL-20, an anti-angiogenic cytokine that inhibits COX-2 expression.
Biochemical and biophysical research communications 2005;333(2):470-5.
2005: Sharma Sherven; Yang Seok-Chul; Zhu Li; Reckamp Karen; Gardner Brian; Baratelli Felicita; Huang Min; Batra Raj K; Dubinett Steven M
Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer.
Cancer research 2005;65(12):5211-20.
2005: Zeng Gang; Aldridge Michael E; Wang Yu; Pantuck Allan J; Wang Allen Y; Liu Yue-xiang; Han Yan; Yuan Yan-hua; Robbins Paul F; Dubinett Steven M; deKernion Jean B; Belldegrun Arie S
Dominant B cell epitope from NY-ESO-1 recognized by sera from a wide spectrum of cancer patients: implications as a potential biomarker.
International journal of cancer. Journal international du cancer 2005;114(2):268-73.
2005: Gamradt Seth C; Feeley Brian T; Liu Nancy Q; Roostaeian Jason; Lin Ying Q; Zhu Li X; Sharma Sherven; Dubinett Steven M; Lieberman Jay R
The effect of cyclooxygenase-2 (COX-2) inhibition on human prostate cancer induced osteoblastic and osteolytic lesions in bone.
Anticancer research 2005;25(1A):107-15.
2004: Strieter Robert M; Belperio John A; Burdick Marie D; Sharma Sherven; Dubinett Steven M; Keane Michael P
CXC chemokines: angiogenesis, immunoangiostasis, and metastases in lung cancer.
Annals of the New York Academy of Sciences 2004;1028():351-60.
2004: Baratelli Felicita E; Heuzé-Vourc'h Nathalie; Krysan Kostyantyn; Dohadwala Mariam; Riedl Karen; Sharma Sherven; Dubinett Steven M
Prostaglandin E2-dependent enhancement of tissue inhibitors of metalloproteinases-1 production limits dendritic cell migration through extracellular matrix.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(9):5458-66.
2004: Mao Jenny T; Tsu I-Hsien; Dubinett Steven M; Adams Bradley; Sarafian Theodore; Baratelli Felicita; Roth Michael D; Serio Kenneth J
Modulation of pulmonary leukotriene B4 production by cyclooxygenase-2 inhibitors and lipopolysaccharide.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(20):6872-8.
2004: Põld Mehis; Krysan Kostyantyn; Põld Anu; Dohadwala Mariam; Heuze-Vourc'h Nathalie; Mao Jenny T; Riedl Karen L; Sharma Sherven; Dubinett Steven M
Cyclooxygenase-2 modulates the insulin-like growth factor axis in non-small-cell lung cancer.
Cancer research 2004;64(18):6549-55.
2004: Krysan Kostyantyn; Dalwadi Harnisha; Sharma Sherven; Põld Mehis; Dubinett Steven
Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer.
Cancer research 2004;64(18):6359-62.
2004: Dubinett Steven M; Elashoff David; Meyerson Matthew
Assessing prognosis in non-small-cell lung cancer: avenues to a more complete picture?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(16):3209-11.
2004: Zhang Ling; Keane Michael P; Zhu Li X; Sharma Sherven; Rozengurt Enrique; Strieter Robert M; Dubinett Steven M; Huang Min
Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis.
The Journal of biological chemistry 2004;279(27):28315-9.
2004: Riedl Karen; Krysan Kostyantyn; Põld Mehis; Dalwadi Harnisha; Heuze-Vourc'h Nathalie; Dohadwala Mariam; Liu Ming; Cui Xiaoyan; Figlin Robert; Mao Jenny T; Strieter Robert; Sharma Sherven; Dubinett Steven M
Multifaceted roles of cyclooxygenase-2 in lung cancer.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2004;7(3):169-84.
2004: Krysan Kostyantyn; Dohadwala Mariam; Luo Jie; Lin Ying; Zhu Li; Heuze-Vourc'h Nathalie; Goodglick Lee; Merchant Farrukh; Seligson David; Pold Mehis; Strieter Robert; Sharma Sherven; Dubinett Steven
Cyclooxygenase-2-dependent expression of survivin in non-small cell lung cancer.
Chest 2004;125(5 Suppl):140S.
2004: Sandler Alan B; Dubinett Steven M
COX-2 inhibition and lung cancer.
Seminars in oncology 2004;31(2 Suppl 7):45-52.
2004: Yang Seok-Chul; Hillinger Sven; Riedl Karen; Zhang Ling; Zhu Li; Huang Min; Atianzar Kimberly; Kuo Brian Y; Gardner Brian; Batra Raj K; Strieter Robert M; Dubinett Steven M; Sharma Sherven
Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(8):2891-901.
2004: Põld Mehis; Zhu Li X; Sharma Sherven; Burdick Marie D; Lin Ying; Lee Peter P N; Põld Anu; Luo Jie; Krysan Kostyantyn; Dohadwala Mariam; Mao Jenny T; Batra Raj K; Strieter Robert M; Dubinett Steven M
Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer.
Cancer research 2004;64(5):1853-60.
2004: Gardner Brian; Zhu Li X; Roth Michael D; Tashkin Donald P; Dubinett Steven M; Sharma Sherven
Cocaine modulates cytokine and enhances tumor growth through sigma receptors.
Journal of neuroimmunology 2004;147(1-2):95-8.
2004: Krysan Kostyantyn; Merchant Farrukh H; Zhu Li; Dohadwala Mariam; Luo Jie; Lin Ying; Heuze-Vourc'h Nathalie; Põld Mehis; Seligson David; Chia David; Goodglick Lee; Wang Hejing; Strieter Robert; Sharma Sherven; Dubinett Steven
COX-2-dependent stabilization of survivin in non-small cell lung cancer.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(1):206-8.
2003: Mao Jenny T; Roth Michael D; Serio Kenneth J; Baratelli Felicita; Zhu Li; Holmes E Carmack; Strieter Robert M; Dubinett Steven M
Celecoxib modulates the capacity for prostaglandin E2 and interleukin-10 production in alveolar macrophages from active smokers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(16 Pt 1):5835-41.
2003: Hillinger Sven; Yang Seok-Chul; Zhu Li; Huang Min; Duckett Russell; Atianzar Kimberly; Batra Raj K; Strieter Robert M; Dubinett Steven M; Sharma Sherven
EBV-induced molecule 1 ligand chemokine (ELC/CCL19) promotes IFN-gamma-dependent antitumor responses in a lung cancer model.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6457-65.
2003: Riedl Karen; Baratelli Felicita; Batra Raj K; Yang Seok Chul; Luo Jie; Escuadro Brian; Figlin Robert; Strieter Robert; Sharma Sherven; Dubinett Steven
Overexpression of CCL-21/secondary lymphoid tissue chemokine in human dendritic cells augments chemotactic activities for lymphocytes and antigen presenting cells.
Molecular cancer 2003;2():35.
2003: Sharma Sherven; Batra Raj K; Yang Seok Chul; Hillinger Sven; Zhu Li; Atianzar Kimberly; Strieter Robert M; Riedl Karen; Huang Min; Dubinett Steven M
Interleukin-7 gene-modified dendritic cells reduce pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
Human gene therapy 2003;14(16):1511-24.
2003: Gardner Brian; Zhu Li X; Sharma Sherven; Tashkin Donald P; Dubinett Steven M
Methanandamide increases COX-2 expression and tumor growth in murine lung cancer.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(14):2157-9.
2003: Zhang Ling; Sharma Sherven; Zhu Li X; Kogai Takahiko; Hershman Jerome M; Brent Gregory A; Dubinett Steven M; Huang Min
Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells.
Cancer research 2003;63(16):5065-72.
2003: Sharma Sherven; Yang Seok-Chul; Hillinger Sven; Zhu Li X; Huang Min; Batra Raj K; Lin Jeff F; Burdick Marie D; Strieter Robert M; Dubinett Steven M
SLC/CCL21-mediated anti-tumor responses require IFNgamma, MIG/CXCL9 and IP-10/CXCL10.
Molecular cancer 2003;2():22.
2003: Zhu Li X; Sharma Sherven; Gardner Brian; Escuadro Brian; Atianzar Kimberly; Tashkin Donald P; Dubinett Steven M
IL-10 mediates sigma 1 receptor-dependent suppression of antitumor immunity.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(7):3585-91.
2003: Sharma Sherven; Stolina Marina; Yang Seok-Chul; Baratelli Felicita; Lin Jeff F; Atianzar Kimberly; Luo Jie; Zhu Li; Lin Ying; Huang Min; Dohadwala Mariam; Batra Raj K; Dubinett Steven M
Tumor cyclooxygenase 2-dependent suppression of dendritic cell function.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):961-8.
2003: Heuze-Vourc'h Nathalie; Zhu Li; Krysan Kostyantyn; Batra Raj K; Sharma Sherven; Dubinett Steven M
Abnormal interleukin 10Ralpha expression contributes to the maintenance of elevated cyclooxygenase-2 in non-small cell lung cancer cells.
Cancer research 2003;63(4):766-70.
2003: Batra Raj K; Lin Ying; Sharma Sherven; Dohadwala Mariam; Luo Jie; Pold Mehis; Dubinett Steven M
Non-small cell lung cancer-derived soluble mediators enhance apoptosis in activated T lymphocytes through an I kappa B kinase-dependent mechanism.
Cancer research 2003;63(3):642-6.
2003: Dubinett Steven M; Sharma Sherven; Huang Min; Dohadwala Mariam; Pold Mehis; Mao Jenny T
Cyclooxygenase-2 in lung cancer.
Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 2003;37():138-62.
2003: Sharma Sherven; Huang Min; Dohadwala Mariam; Pold Mehis; Batra Raj K; Dubinett Steven M
Cyclooxygenase 2-dependent regulation of antitumor immunity in lung cancer.
Methods in molecular medicine 2003;75():723-36.
2003: Sharma Sherven; Yang Seok Chul; Batra Raj K; Dubinett Steven M
Intratumoral therapy with cytokine gene-modified dendritic cells in murine lung cancer models.
Methods in molecular medicine 2003;75():711-22.
2002: Dohadwala Mariam; Batra Raj K; Luo Jie; Lin Ying; Krysan Kostyantyn; Pold Mehis; Sharma Sherven; Dubinett Steven M
Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion.
The Journal of biological chemistry 2002;277(52):50828-33.
2002: Tashkin Donald P; Baldwin Gayle C; Sarafian Theodore; Dubinett Steven; Roth Michael D
Respiratory and immunologic consequences of marijuana smoking.
Journal of clinical pharmacology 2002;42(11 Suppl):71S-81S.
2002: Bernal Ray M; Sharma Sherven; Gardner Brian K; Douglas Joanne T; Bergelson Jeffrey M; Dubinett Steven M; Batra Raj K
Soluble coxsackievirus adenovirus receptor is a putative inhibitor of adenoviral gene transfer in the tumor milieu.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(6):1915-23.
2002: Basak Saroj K; Harui Airi; Stolina Marina; Sharma Sherven; Mitani Kohnosuke; Dubinett Steven M; Roth Michael D
Increased dendritic cell number and function following continuous in vivo infusion of granulocyte macrophage-colony-stimulating factor and interleukin-4.
Blood 2002;99(8):2869-79.
2002: Huang Min; Sharma Sherven; Zhu Li X; Keane Michael P; Luo Jie; Zhang Ling; Burdick Marie D; Lin Ying Q; Dohadwala Mariam; Gardner Brian; Batra Raj K; Strieter Robert M; Dubinett Steven M
IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosis.
The Journal of clinical investigation 2002;109(7):931-7.
2002: Põld Mehis; Dohadwala M; Luo J; Lin Y; Dubinett S
Microarray identifies cyclo-oxygenase-2-dependent modulation of insulin-like growth factor binding protein-3 in non-small cell lung cancer cells.
Chest 2002;121(3 Suppl):29S-30S.
2002: Gardner Brian; Zu Li X; Sharma Sherven; Liu Qian; Makriyannis Alexandros; Tashkin Donald P; Dubinett Steven M
Autocrine and paracrine regulation of lymphocyte CB2 receptor expression by TGF-beta.
Biochemical and biophysical research communications 2002;290(1):91-6.
2001: Sharma S; Stolina M; Zhu L; Lin Y; Batra R; Huang M; Strieter R; Dubinett S M
Secondary lymphoid organ chemokine reduces pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
Cancer research 2001;61(17):6406-12.
2001: Huang M; Batra R K; Kogai T; Lin Y Q; Hershman J M; Lichtenstein A; Sharma S; Zhu L X; Brent G A; Dubinett S M
Ectopic expression of the thyroperoxidase gene augments radioiodide uptake and retention mediated by the sodium iodide symporter in non-small cell lung cancer.
Cancer gene therapy 2001;8(8):612-8.
2001: Dohadwala M; Luo J; Zhu L; Lin Y; Dougherty G J; Sharma S; Huang M; Pold M; Batra R K; Dubinett S M
Non-small cell lung cancer cyclooxygenase-2-dependent invasion is mediated by CD44.
The Journal of biological chemistry 2001;276(24):20809-12.
2000: Zhu L X; Sharma S; Stolina M; Gardner B; Roth M D; Tashkin D P; Dubinett S M
Delta-9-tetrahydrocannabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):373-80.
2000: Batra R K; Dubinett S M; Henkle B W; Sharma S; Gardner B K
Adenoviral gene transfer is inhibited by soluble factors in malignant pleural effusions.
American journal of respiratory cell and molecular biology 2000;22(5):613-9.
2000: Dubinett S M; Batra R K; Miller P W; Sharma S
Tumor antigens in thoracic malignancy.
American journal of respiratory cell and molecular biology 2000;22(5):524-7.
2000: Sharma S; Stolina M; Luo J; Strieter R M; Burdick M; Zhu L X; Batra R K; Dubinett S M
Secondary lymphoid tissue chemokine mediates T cell-dependent antitumor responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4558-63.
2000: Kiertscher S M; Luo J; Dubinett S M; Roth M D
Tumors promote altered maturation and early apoptosis of monocyte-derived dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1269-76.
2000: Miller P W; Sharma S; Stolina M; Butterfield L H; Luo J; Lin Y; Dohadwala M; Batra R K; Wu L; Economou J S; Dubinett S M
Intratumoral administration of adenoviral interleukin 7 gene-modified dendritic cells augments specific antitumor immunity and achieves tumor eradication.
Human gene therapy 2000;11(1):53-65.
2000: Stolina M; Sharma S; Lin Y; Dohadwala M; Gardner B; Luo J; Zhu L; Kronenberg M; Miller P W; Portanova J; Lee J C; Dubinett S M
Specific inhibition of cyclooxygenase 2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):361-70.
1999: Sharma S; Stolina M; Lin Y; Gardner B; Miller P W; Kronenberg M; Dubinett S M
T cell-derived IL-10 promotes lung cancer growth by suppressing both T cell and APC function.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(9):5020-8.
1998: Miller P W; Sharma S; Stolina M; Chen K; Zhu L; Paul R W; Dubinett S M
Dendritic cells augment granulocyte-macrophage colony-stimulating factor (GM-CSF)/herpes simplex virus thymidine kinase-mediated gene therapy of lung cancer.
Cancer gene therapy 1998;5(6):380-9.
1998: Smith R M; Dubinett S M; Grudko K; Rosenow E C; Budman D R; Schnader J
Clinical conference on management dilemmas: a young woman with a 10-cm chest mass.
Chest 1998;114(1):295-306.
1998: Huang M; Stolina M; Sharma S; Mao J T; Zhu L; Miller P W; Wollman J; Herschman H; Dubinett S M
Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production.
Cancer research 1998;58(6):1208-16.
1998: Schneider S C; Deng H K; Rottinger B; Sharma S; Stolina M; Bonpane C; Miller A; Dubinett S; Kyewski B; Sercarz E
Tolerance and determinant hierarchy.
Novartis Foundation symposium 1998;215():54-66; discussion 66-72.
1997: Sharma S; Miller P W; Stolina M; Zhu L; Huang M; Paul R W; Dubinett S M
Multicomponent gene therapy vaccines for lung cancer: effective eradication of established murine tumors in vivo with interleukin-7/herpes simplex thymidine kinase-transduced autologous tumor and ex vivo activated dendritic cells.
Gene therapy 1997;4(12):1361-70.
1997: Baldwin G C; Tashkin D P; Buckley D M; Park A N; Dubinett S M; Roth M D
Marijuana and cocaine impair alveolar macrophage function and cytokine production.
American journal of respiratory and critical care medicine 1997;156(5):1606-13.
1997: Mao J T; Zhu L X; Sharma S; Chen K; Huang M; Santiago S J; Gulsurd J; Tashkin D P; Dubinett S M
Cocaine inhibits human endothelial cell IL-8 production: the role of transforming growth factor-beta.
Cellular immunology 1997;181(1):38-43.
1997: Tashkin D P; Roth M D; Dubinett S M
Medicinal marijuana?
The New England journal of medicine 1997;336(16):1186; author reply 1186-7.
1997: Arthur J F; Butterfield L H; Roth M D; Bui L A; Kiertscher S M; Lau R; Dubinett S; Glaspy J; McBride W H; Economou J S
A comparison of gene transfer methods in human dendritic cells.
Cancer gene therapy 1997;4(1):17-25.
1996: Huang M; Sharma S; Mao J T; Dubinett S M
Non-small cell lung cancer-derived soluble mediators and prostaglandin E2 enhance peripheral blood lymphocyte IL-10 transcription and protein production.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(12):5512-20.
1996: Mao J T; Huang M; Wang J; Sharma S; Tashkin D P; Dubinett S M
Cocaine down-regulates IL-2-induced peripheral blood lymphocyte IL-8 and IFN-gamma production.
Cellular immunology 1996;172(2):217-23.
1996: Sharma S; Wang J; Huang M; Paul R W; Lee P; McBride W H; Economou J S; Roth M D; Kiertscher S M; Dubinett S M
Interleukin-7 gene transfer in non-small-cell lung cancer decreases tumor proliferation, modifies cell surface molecule expression, and enhances antitumor reactivity.
Cancer gene therapy 1996;3(5):302-13.
1996: Wang J; Huang M; Lee P; Komanduri K; Sharma S; Chen G; Dubinett S M
Interleukin-8 inhibits non-small cell lung cancer proliferation: a possible role for regulation of tumor growth by autocrine and paracrine pathways.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1996;16(1):53-60.
1995: Huang M; Wang J; Lee P; Sharma S; Mao J T; Meissner H; Uyemura K; Modlin R; Wollman J; Dubinett S M
Human non-small cell lung cancer cells express a type 2 cytokine pattern.
Cancer research 1995;55(17):3847-53.
1995: Kim J; Modlin R L; Moy R L; Dubinett S M; McHugh T; Nickoloff B J; Uyemura K
IL-10 production in cutaneous basal and squamous cell carcinomas. A mechanism for evading the local T cell immune response.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(4):2240-7.
1995: Dubinett S M; Huang M; Dhanani S; Economou J S; Wang J; Lee P; Sharma S; Dougherty G J; McBride W H
Down-regulation of murine fibrosarcoma transforming growth factor-beta 1 expression by interleukin 7.
Journal of the National Cancer Institute 1995;87(8):593-7.
1994: Dubinett S M; Huang M; Lichtenstein A; McBride W H; Wang J; Markovitz G; Kelley D; Grody W W; Mintz L E; Dhanani S
Tumor necrosis factor-alpha plays a central role in interleukin-2-induced pulmonary vascular leak and lymphocyte accumulation.
Cellular immunology 1994;157(1):170-80.
1994: Dhanani S; Huang M; Wang J; Dubinett S M
Interferon-alpha inhibits murine macrophage transforming growth factor-beta mRNA expression.
Inflammation 1994;18(3):301-9.
1994: Kelley D M; Lichtenstein A; Wang J; Taylor A N; Dubinett S M
Corticotropin-releasing factor reduces lipopolysaccharide-induced pulmonary vascular leak.
Immunopharmacology and immunotoxicology 1994;16(2):139-48.
1993: Miller A R; McBride W H; Dubinett S M; Dougherty G J; Thacker J D; Shau H; Kohn D B; Moen R C; Walker M J; Chiu R
Transduction of human melanoma cell lines with the human interleukin-7 gene using retroviral-mediated gene transfer: comparison of immunologic properties with interleukin-2.
Blood 1993;82(12):3686-94.
1993: Dubinett S M; Huang M; Dhanani S; Wang J; Beroiza T
Down-regulation of macrophage transforming growth factor-beta messenger RNA expression by IL-7.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(12):6670-80.
1993: Dubinett S M; Kradin R L
Cytokine immunotherapy of non-small cell lung cancer.
Regional immunology 1993;5(3-4):232-43.
1993: Dubinett S M; Patrone L; Huang M; Markowitz J; McBride W H; Economou J S; Tobias J; Kelley D; Yan D; Seelig M
Interleukin-2-responsive wound-infiltrating lymphocytes in surgical adjuvant cancer immunotherapy.
Immunological investigations 1993;22(1):13-23.
1993: Dubinett S M; Huang M; Dhanani S; Kelley D; Lichtenstein A; Grody W W; Mintz L E
In situ regulation of pulmonary macrophage TNF-alpha mRNA expression by IL2.
Chest 1993;103(2 Suppl):91S-94S.
1993: Nguyen Q H; Moy R L; Roth M D; Yamamoto R; Tomono S; Dubinett S M
Expression of CD45 isoforms in fresh and IL-2-cultured tumor-infiltrating lymphocytes from basal cell carcinoma.
Cellular immunology 1993;146(2):421-30.
1993: Dubinett S M; Patrone L; Tobias J; Cochran A J; Wen D R; McBride W H
Intratumoral interleukin-2 immunotherapy: activation of tumor-infiltrating and splenic lymphocytes in vivo.
Cancer immunology, immunotherapy : CII 1993;36(3):156-62.
1992: McDonagh J; Fossel E T; Kradin R L; Dubinett S M; Laposata M; Hallaq Y A
Effects of tumor necrosis factor-alpha on peroxidation of plasma lipoprotein lipids in experimental animals and patients.
Blood 1992;80(12):3217-26.
1992: McBride W H; Thacker J D; Comora S; Economou J S; Kelley D; Hogge D; Dubinett S M; Dougherty G J
Genetic modification of a murine fibrosarcoma to produce interleukin 7 stimulates host cell infiltration and tumor immunity.
Cancer research 1992;52(14):3931-7.
1991: Dubinett S M; Callahan R J; Xia W J; Ahmad M; Strauss H W; Kradin R L
Cytokine administration alters the distribution of activated lymphocytes to the lung.
Pathobiology : journal of immunopathology, molecular and cellular biology 1991;59(6):372-7.
1989: Dubinett S M; Kurnick J T; Kradin R L
Adoptive immunotherapy of murine pulmonary metastases with interleukin 2 and interferon-gamma.
American journal of respiratory cell and molecular biology 1989;1(5):361-9.
1989: Gallagher W J; Dubinett S M; Hoover H C; Kradin R L
Efficacy of adjuvant interleukin-2 after excision of BALB/c fibrosarcomas.
Surgery 1989;106(2):120-5.
1989: Kradin R L; Kurnick J T; Lazarus D S; Preffer F I; Dubinett S M; Pinto C E; Gifford J; Davidson E; Grove B; Callahan R J
Tumour-infiltrating lymphocytes and interleukin-2 in treatment of advanced cancer.
Lancet 1989;1(8638):577-80.
1989: Kradin R L; Kurnick J T; Preffer F I; Dubinett S M; Dickersin G R; Pinto C
Adoptive immunotherapy with IL-2 results in the loss of delayed-type hypersensitivity responses and the development of immediate hypersensitivity to recall antigens.
Clinical immunology and immunopathology 1989;50(2):184-95.
1988: Kradin R; Dubinett S; Mullin J; Boyle L; Strauss H W; Bourgoin P M; Preffer F I; Kurnick J
Treatment of patients with advanced cancer using tumor-infiltrating lymphocytes and interleukin 2.
Transplantation proceedings 1988;20(2):336-8.
1987: Kradin R L; Boyle L A; Preffer F I; Callahan R J; Barlai-Kovach M; Strauss H W; Dubinett S; Kurnick J T
Tumor-derived interleukin-2-dependent lymphocytes in adoptive immunotherapy of lung cancer.
Cancer immunology, immunotherapy : CII 1987;24(1):76-85.

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