FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

George Dubyak

Research Profile

Chemicals & Drugs

Anatomy

Physiology

Living Beings

Mouse
Rats

Concepts & Ideas

Kinetics

Co-author Network

Publications

TOP 3
George R Dubyak
Dueling nucleosides: cross-regulation of extracellular adenosine by guanosine. Focus on "Extracellular guanosine regulates extracellular adenosine levels".
George R Dubyak
Function without form: an ongoing search for maxi-anion channel proteins. Focus on "Maxi-anion channel and pannexin 1 hemichannel constitute separate pathways for swelling-induced ATP release in murine L929 fibrosarcoma cells".
George R Dubyak
P2X7 receptor regulation of non-classical secretion from immune effector cells.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of George Dubyak (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: George R Dubyak
Dueling nucleosides: cross-regulation of extracellular adenosine by guanosine. Focus on "Extracellular guanosine regulates extracellular adenosine levels".
American journal of physiology. Cell physiology 2013;304(5):C403-5.
2012: George R Dubyak
Function without form: an ongoing search for maxi-anion channel proteins. Focus on "Maxi-anion channel and pannexin 1 hemichannel constitute separate pathways for swelling-induced ATP release in murine L929 fibrosarcoma cells".
American journal of physiology. Cell physiology 2012;303(9):C913-5.
2012: George R Dubyak
P2X7 receptor regulation of non-classical secretion from immune effector cells.
Cellular microbiology 2012;14(11):1697-706.
2011: Katherine E Trueblood; Susanne Mohr; George R Dubyak
Purinergic regulation of high-glucose-induced caspase-1 activation in the rat retinal Müller cell line rMC-1.
American journal of physiology. Cell physiology 2011;301(5):C1213-23.
2011: Ricardo Villa-Bellosta; Xiaonan Wang; George R Dubyak; José Luis Millán; W Charles O'neill
Extracellular pyrophosphate metabolism and calcification in vascular smooth muscle.
American journal of physiology. Heart and circulatory physiology 2011;301(1):H61-8.
2011: Yan Qu; Shahram Misaghi; Kim Newton; Laurie L Gilmour; Salina Louie; James E Cupp; George R Dubyak; David Hackos; Vishva M Dixit
Pannexin-1 is required for ATP release during apoptosis but not for inflammasome activation.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(11):6553-61.
2011: George R Dubyak
Charge of the mito brigade. Focus on "Changes in mitochondrial surface charge mediate recruitment of signaling molecules during apoptosis".
American journal of physiology. Cell physiology 2011;300(1):C11-3.
2010: Lakshmi Ramachandra; Yan Qu; Ying Wang; Colleen J Lewis; Brian A Cobb; Kiyoshi Takatsu; W Henry Boom; George R Dubyak; Clifford V Harding
Mycobacterium tuberculosis synergizes with ATP to induce release of microvesicles and exosomes containing major histocompatibility complex class II molecules capable of antigen presentation.
Infection and immunity 2010;78(12):5116-25.
2010: Domenick A Prosdocimo; Steven C Wyler; Andrea M Romani; W Charles O'Neill; George R Dubyak
Regulation of vascular smooth muscle cell calcification by extracellular pyrophosphate homeostasis: synergistic modulation by cyclic AMP and hyperphosphatemia.
American journal of physiology. Cell physiology 2010;298(3):C702-13.
2010: Andrew E Blum; B Corbett Walsh; George R Dubyak
Extracellular osmolarity modulates G protein-coupled receptor-dependent ATP release from 1321N1 astrocytoma cells.
American journal of physiology. Cell physiology 2010;298(2):C386-96.
2009: Shiyuan Hong; Anette Brass; Michel Seman; Friedrich Haag; Friedrich Koch-Nolte; George R Dubyak
Basal and inducible expression of the thiol-sensitive ART2.1 ecto-ADP-ribosyltransferase in myeloid and lymphoid leukocytes.
Purinergic signalling 2009;5(3):369-83.
2009: Shiyuan Hong; Nicole Schwarz; Anette Brass; Michel Seman; Friedrich Haag; Friedrich Koch-Nolte; William P Schilling; George R Dubyak
Differential regulation of P2X7 receptor activation by extracellular nicotinamide adenine dinucleotide and ecto-ADP-ribosyltransferases in murine macrophages and T cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(1):578-92.
2009: Yan Qu; George R Dubyak
P2X7 receptors regulate multiple types of membrane trafficking responses and non-classical secretion pathways.
Purinergic signalling 2009;5(2):163-73.
2009: Yan Qu; Lakshmi Ramachandra; Susanne Mohr; luigi franchi; Clifford V Harding; Gabriel Nunez; George R Dubyak
P2X7 receptor-stimulated secretion of MHC class II-containing exosomes requires the ASC/NLRP3 inflammasome but is independent of caspase-1.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):5052-62.
2009: Domenick A Prosdocimo; Dezmond C Douglas; Andrea M Romani; W Charles O'Neill; George R Dubyak
Autocrine ATP release coupled to extracellular pyrophosphate accumulation in vascular smooth muscle cells.
American journal of physiology. Cell physiology 2009;296(4):C828-39.
2009: George R Dubyak
Both sides now: multiple interactions of ATP with pannexin-1 hemichannels. Focus on "A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP".
American journal of physiology. Cell physiology 2009;296(2):C235-41.
2009: luigi franchi; Grace Chen; Noemi Marina-Garcia; Akira Abe; Yan Qu; Shunzhong Bao; James A Shayman; John Turk; George R Dubyak; Gabriel Núñez
Calcium-independent phospholipase A2 beta is dispensable in inflammasome activation and its inhibition by bromoenol lactone.
Journal of innate immunity 2009;1(6):607-17.
2008: Andrew E Blum; Sheldon M Joseph; Ronald J Przybylski; George R Dubyak
Rho-family GTPases modulate Ca(2+) -dependent ATP release from astrocytes.
American journal of physiology. Cell physiology 2008;295(1):C231-41.
2008: Vielska M Brautigam; George R Dubyak; Jessica M Crain; Jyoti J Watters
The inflammatory effects of UDP-glucose in N9 microglia are not mediated by P2Y14 receptor activation.
Purinergic signalling 2008;4(1):73-8.
2008: Michael G Strainic; Jinbo Liu; Danping Huang; Fengqi An; Peter N Lalli; Nasima Muqim; Virginia S Shapiro; George R Dubyak; Peter S Heeger; M Edward Medof
Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells.
Immunity 2008;28(3):425-35.
2007: George R Dubyak
Go it alone no more--P2X7 joins the society of heteromeric ATP-gated receptor channels.
Molecular pharmacology 2007;72(6):1402-5.
2007: Shiyuan Hong; Anette Brass; Michel Seman; Friedrich Haag; Friedrich Koch-Nolte; George R Dubyak
Lipopolysaccharide, IFN-gamma, and IFN-beta induce expression of the thiol-sensitive ART2.1 Ecto-ADP-ribosyltransferase in murine macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):6215-27.
2007: Yan Qu; luigi franchi; Gabriel Nunez; George R Dubyak
Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1913-25.
2007: luigi franchi; Thirumala-Devi Kanneganti; George R Dubyak; Gabriel Núñez
Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria.
The Journal of biological chemistry 2007;282(26):18810-8.
2006: Bryan T Carroll; George R Dubyak; Margaret M Sedensky; Phil G Morgan
Sulfated signal from ASJ sensory neurons modulates stomatin-dependent coordination in Caenorhabditis elegans.
The Journal of biological chemistry 2006;281(47):35989-96.
2006: Zhimin Feng; George R Dubyak; Michael M Lederman; Aaron Weinberg
Cutting edge: human beta defensin 3--a novel antagonist of the HIV-1 coreceptor CXCR4.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):782-6.
2006: Elke De Vuyst; Elke Decrock; Liesbet Cabooter; George R Dubyak; Christian C Naus; W Howard Evans; Luc Leybaert
Intracellular calcium changes trigger connexin 32 hemichannel opening.
The EMBO journal 2006;25(1):34-44.
2005: Philip A Verhoef; Sylvia B Kertesy; Kathleen Lundberg; J Michelle Kahlenberg; George R Dubyak
Inhibitory effects of chloride on the activation of caspase-1, IL-1beta secretion, and cytolysis by the P2X7 receptor.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(11):7623-34.
2005: J Michelle Kahlenberg; Kathleen Lundberg; Sylvia B Kertesy; Yan Qu; George R Dubyak
Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kappaB-driven protein synthesis.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(11):7611-22.
2005: Sivaparkasam Balasubramanian; Michael T Sturniolo; George R Dubyak; Richard L Eckert
Human epidermal keratinocytes undergo (-)-epigallocatechin-3-gallate-dependent differentiation but not apoptosis.
Carcinogenesis 2005;26(6):1100-8.
2005: Nadine N Johnson-Farley; Sylvia B Kertesy; George R Dubyak; Daniel S Cowen
Enhanced activation of Akt and extracellular-regulated kinase pathways by simultaneous occupancy of Gq-coupled 5-HT2A receptors and Gs-coupled 5-HT7A receptors in PC12 cells.
Journal of neurochemistry 2005;92(1):72-82.
2004: George R Dubyak
Ion homeostasis, channels, and transporters: an update on cellular mechanisms.
Advances in physiology education 2004;28(1-4):143-54.
2004: Philip A Verhoef; Sylvia B Kertesy; Mark Estacion; William Schilling; George R Dubyak
Maitotoxin induces biphasic interleukin-1beta secretion and membrane blebbing in murine macrophages.
Molecular pharmacology 2004;66(4):909-20.
2004: J Michelle Kahlenberg; George R Dubyak
Differing caspase-1 activation states in monocyte versus macrophage models of IL-1beta processing and release.
Journal of leukocyte biology 2004;76(3):676-84.
2004: Sheldon M Joseph; Matthew A Pifer; Ronald J Przybylski; George R Dubyak
Methylene ATP analogs as modulators of extracellular ATP metabolism and accumulation.
British journal of pharmacology 2004;142(6):1002-14.
2004: J Michelle Kahlenberg; George R Dubyak
Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release.
American journal of physiology. Cell physiology 2004;286(5):C1100-8.
2003: Reza D Beigi; Sylvia B Kertesy; Gretchen Aquilina; George R Dubyak
Oxidized ATP (oATP) attenuates proinflammatory signaling via P2 receptor-independent mechanisms.
British journal of pharmacology 2003;140(3):507-19.
2003: Loren C Denlinger; Julie A Sommer; Karen Parker; Lalitha Gudipaty; Philip L Fisette; Jyoti W Watters; Richard A Proctor; George R Dubyak; Paul J Bertics
Mutation of a dibasic amino acid motif within the C terminus of the P2X7 nucleotide receptor results in trafficking defects and impaired function.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1304-11.
2003: Lalitha Gudipaty; Jonathan Munetz; Philip A Verhoef; George R Dubyak
Essential role for Ca2+ in regulation of IL-1beta secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells.
American journal of physiology. Cell physiology 2003;285(2):C286-99.
2003: Sheldon M Joseph; Marisa R Buchakjian; George R Dubyak
Colocalization of ATP release sites and ecto-ATPase activity at the extracellular surface of human astrocytes.
The Journal of biological chemistry 2003;278(26):23331-42.
2003: Philip A Verhoef; Mark Estacion; William Schilling; George R Dubyak
P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1 beta release.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(11):5728-38.
2003: George R Dubyak
Knock-out mice reveal tissue-specific roles of P2Y receptor subtypes in different epithelia.
Molecular pharmacology 2003;63(4):773-6.
2002: David H Canaday; Reza D Beigi; Richard F Silver; Clifford V Harding; W Henry Boom; George R Dubyak
ATP and control of intracellular growth of mycobacteria by T cells.
Infection and immunity 2002;70(11):6456-9.
2002: Wangzhong Chen; R Gnana Ravi; Sylvia B Kertesy; George R Dubyak; Kenneth Alan Jacobson
Functionalized congeners of tyrosine-based P2X(7) receptor antagonists: probing multiple sites for linking and dimerization.
Bioconjugate chemistry 2002;13(5):1100-11.
2002: George R Dubyak
Focus on "extracellular ATP signaling and P2X nucleotide receptors in monolayers of primary human vascular endothelial cells".
American journal of physiology. Cell physiology 2002;282(2):C242-4.
2001: Loren C Denlinger; Philip L Fisette; Julie A Sommer; Jyoti J Watters; Usha Prabhu; George R Dubyak; Richard A Proctor; Paul J Bertics
Cutting edge: the nucleotide receptor P2X7 contains multiple protein- and lipid-interaction motifs including a potential binding site for bacterial lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(4):1871-6.
2001: Colleen Tagliarino; John J Pink; George R Dubyak; Anna-Liisa Nieminen; David A Boothman
Calcium is a key signaling molecule in beta-lapachone-mediated cell death.
The Journal of biological chemistry 2001;276(22):19150-9.
2001: Lalitha Gudipaty; BD Humphreys; G Buell; George R Dubyak
Regulation of P2X(7) nucleotide receptor function in human monocytes by extracellular ions and receptor density.
American journal of physiology. Cell physiology 2001;280(4):C943-53.
2001: YC Kim; S G Brown; T Kendall Harden; José L Boyer; George R Dubyak; BF King; Geoffrey Burnstock; Kenneth Alan Jacobson
Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors.
Journal of medicinal chemistry 2001;44(3):340-9.
2000: Reza D Beigi; George R Dubyak
Endotoxin activation of macrophages does not induce ATP release and autocrine stimulation of P2 nucleotide receptors.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):7189-98.
2000: Sivaparkasam Balasubramanian; C Agarwal; Tatiana Efimova; George R Dubyak; Eric B Banks; Jean F Welter; Richard L Eckert
Thapsigargin suppresses phorbol ester-dependent human involucrin promoter activity by suppressing CCAAT-enhancer-binding protein alpha (C/EBPalpha) DNA binding.
The Biochemical journal 2000;350 Pt 3():791-6.
2000: BD Humphreys; J Rice; Sylvia B Kertesy; George R Dubyak
Stress-activated protein kinase/JNK activation and apoptotic induction by the macrophage P2X7 nucleotide receptor.
The Journal of biological chemistry 2000;275(35):26792-8.
2000: George R Dubyak
Purinergic signaling at immunological synapses.
Journal of the autonomic nervous system 2000;81(1-3):64-8.
1999: William Schilling; T Wasylyna; George R Dubyak; BD Humphreys; William G Sinkins
Maitotoxin and P2Z/P2X(7) purinergic receptor stimulation activate a common cytolytic pore.
The American journal of physiology 1999;277(4 Pt 1):C766-76.
1999: Reza D Beigi; E Kobatake; M Aizawa; George R Dubyak
Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase.
The American journal of physiology 1999;276(1 Pt 1):C267-78.
1998: BD Humphreys; George R Dubyak
Modulation of P2X7 nucleotide receptor expression by pro- and anti-inflammatory stimuli in THP-1 monocytes.
Journal of leukocyte biology 1998;64(2):265-73.
1998: BD Humphreys; C Virginio; Annmarie Surprenant; J Rice; George R Dubyak
Isoquinolines as antagonists of the P2X7 nucleotide receptor: high selectivity for the human versus rat receptor homologues.
Molecular pharmacology 1998;54(1):22-32.
1998: E E Clifford; K Parker; BD Humphreys; Sylvia B Kertesy; George R Dubyak
The P2X1 receptor, an adenosine triphosphate-gated cation channel, is expressed in human platelets but not in human blood leukocytes.
Blood 1998;91(9):3172-81.
1998: Clark W Distelhorst; George R Dubyak
Role of calcium in glucocorticosteroid-induced apoptosis of thymocytes and lymphoma cells: resurrection of old theories by new findings.
Blood 1998;91(3):731-4.
1997: E E Clifford; KA Martin; P Dalal; R Thomas; George R Dubyak
Stage-specific expression of P2Y receptors, ecto-apyrase, and ecto-5'-nucleotidase in myeloid leukocytes.
The American journal of physiology 1997;273(3 Pt 1):C973-87.
1997: Jeffrey R Schelling; N Nkemere; Martha Konieczkowski; KA Martin; George R Dubyak
Angiotensin II activates the beta 1 isoform of phospholipase C in vascular smooth muscle cells.
The American journal of physiology 1997;272(5 Pt 1):C1558-66.
1997: George R Dubyak; Sylvia B Kertesy
Inhibition of GTP gamma S-dependent phospholipase D and Rho membrane association by calphostin is independent of protein kinase C catalytic activity.
Archives of biochemistry and biophysics 1997;341(1):129-39.
1997: KA Martin; Sylvia B Kertesy; George R Dubyak
Down-regulation of P2U-purinergic nucleotide receptor messenger RNA expression during in vitro differentiation of human myeloid leukocytes by phorbol esters or inflammatory activators.
Molecular pharmacology 1997;51(1):97-108.
1996: BD Humphreys; George R Dubyak
Induction of the P2z/P2X7 nucleotide receptor and associated phospholipase D activity by lipopolysaccharide and IFN-gamma in the human THP-1 monocytic cell line.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(12):5627-37.
1996: D Merlin; X Guo; K Martin; Christian L Laboisse; D Landis; George R Dubyak; Ulrich Hopfer
Recruitment of purinergically stimulated Cl- channels from granule membrane to plasma membrane.
The American journal of physiology 1996;271(2 Pt 1):C612-9.
1996: Jeffrey R Schelling; D J Gentry; George R Dubyak
Annexin II inhibition of G protein-regulated inositol trisphosphate formation in rat aortic smooth muscle.
The American journal of physiology 1996;270(4 Pt 2):F682-90.
1996: Y Mitani; George R Dubyak; Faramarz Ismail-Beigi
Induction of GLUT-1 mRNA in response to inhibition of oxidative phosphorylation: role of increased [Ca2+]i.
The American journal of physiology 1996;270(1 Pt 1):C235-42.
1995: Y Mitani; Alireza Behrooz; George R Dubyak; Faramarz Ismail-Beigi
Stimulation of GLUT-1 glucose transporter expression in response to exposure to calcium ionophore A-23187.
The American journal of physiology 1995;269(5 Pt 1):C1228-34.
1994: D J Kusner; George R Dubyak
Guanosine 5'-[gamma-thio]triphosphate induces membrane localization of cytosol-independent phospholipase D activity in a cell-free system from U937 promonocytic leucocytes.
The Biochemical journal 1994;304 ( Pt 2)():485-91.
1994: Jeffrey R Schelling; D J DeLuca; Martha Konieczkowski; R Marzec; John R Sedor; George R Dubyak; Stuart L Linas
Glucocorticoid uncoupling of antiogensin II-dependent phospholipase C activation in rat vascular smooth muscle cells.
Kidney international 1994;46(3):675-82.
1994: Minh Lam; George R Dubyak; L Chen; G Nuñez; R L Miesfeld; Clark W Distelhorst
Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6569-73.
1994: L C Nuttle; George R Dubyak
Differential activation of cation channels and non-selective pores by macrophage P2z purinergic receptors expressed in Xenopus oocytes.
The Journal of biological chemistry 1994;269(19):13988-96.
1993: F K Racke; L G Hammerland; George R Dubyak; Edward F Nemeth
Functional expression of the parathyroid cell calcium receptor in Xenopus oocytes.
FEBS letters 1993;333(1-2):132-6.
1993: N Abughali; George R Dubyak; M F Tosi
Impairment of chemoattractant-stimulated hexose uptake in neonatal neutrophils.
Blood 1993;82(7):2182-7.
1993: D J Kusner; S J Schomisch; George R Dubyak
ATP-induced potentiation of G-protein-dependent phospholipase D activity in a cell-free system from U937 promonocytic leukocytes.
The Journal of biological chemistry 1993;268(27):19973-82.
1993: George R Dubyak; C el-Moatassim
Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides.
The American journal of physiology 1993;265(3 Pt 1):C577-606.
1993: C el-Moatassim; George R Dubyak
Dissociation of the pore-forming and phospholipase D activities stimulated via P2z purinergic receptors in BAC1.2F5 macrophages. Product inhibition of phospholipase D enzyme activity.
The Journal of biological chemistry 1993;268(21):15571-8.
1993: L C Nuttle; C el-Moatassim; George R Dubyak
Expression of the pore-forming P2Z purinoreceptor in Xenopus oocytes injected with poly(A)+ RNA from murine macrophages.
Molecular pharmacology 1993;44(1):93-101.
1993: George R Dubyak; S J Schomisch; D J Kusner; M Xie
Phospholipase D activity in phagocytic leucocytes is synergistically regulated by G-protein- and tyrosine kinase-based mechanisms.
The Biochemical journal 1993;292 ( Pt 1)():121-8.
1992: C el-Moatassim; George R Dubyak
A novel pathway for the activation of phospholipase D by P2z purinergic receptors in BAC1.2F5 macrophages.
The Journal of biological chemistry 1992;267(33):23664-73.
1991: M S Xie; George R Dubyak
Guanine-nucleotide- and adenine-nucleotide-dependent regulation of phospholipase D in electropermeabilized HL-60 granulocytes.
The Biochemical journal 1991;278 ( Pt 1)():81-9.
1991: D S Cowen; Melvin Berger; L Nuttle; George R Dubyak
Chronic treatment with P2-purinergic receptor agonists induces phenotypic modulation of the HL-60 and U937 human myelogenous leukemia cell lines.
Journal of leukocyte biology 1991;50(2):109-22.
1991: M S Xie; L S Jacobs; George R Dubyak
Regulation of phospholipase D and primary granule secretion by P2-purinergic- and chemotactic peptide-receptor agonists is induced during granulocytic differentiation of HL-60 cells.
The Journal of clinical investigation 1991;88(1):45-54.
1991: George R Dubyak
Signal transduction by P2-purinergic receptors for extracellular ATP.
American journal of respiratory cell and molecular biology 1991;4(4):295-300.
1991: M Pinzani; Thomas C Knauss; G F Pierce; P Hsieh; W Kenney; George R Dubyak; Hanna Abboud
Mitogenic signals for platelet-derived growth factor isoforms in liver fat-storing cells.
The American journal of physiology 1991;260(3 Pt 1):C485-91.
1991: P Mené; George R Dubyak; A Scarpa; Michael J Dunn
Regulation of cytosolic pH of cultured mesangial cells by prostaglandin F2 alpha and thromboxane A2.
The American journal of physiology 1991;260(1 Pt 1):C159-66.
1990: D S Cowen; B Baker; George R Dubyak
Pertussis toxin produces differential inhibitory effects on basal, P2-purinergic, and chemotactic peptide-stimulated inositol phospholipid breakdown in HL-60 cells and HL-60 cell membranes.
The Journal of biological chemistry 1990;265(27):16181-9.
1990: D S Cowen; M Sanders; George R Dubyak
P2-purinergic receptors activate a guanine nucleotide-dependent phospholipase C in membranes from HL-60 cells.
Biochimica et biophysica acta 1990;1053(2-3):195-203.
1990: George R Dubyak; J S Fedan
The biologic actions of extracellular adenosine triphosphate.
Comprehensive therapy 1990;16(4):57-61.
1990: George R Dubyak; D S Cowen
Activation of inositol phospholipid-specific phospholipase C by P2-purinergic receptors in human phagocytic leukocytes. Role of pertussis toxin-sensitive G proteins.
Annals of the New York Academy of Sciences 1990;603():227-44; discussion 244-5.
1989: Thomas C Knauss; P Mené; S A Ricanati; Mark Kester; George R Dubyak; S N Emancipator; John R Sedor
Immune complex activation of rat glomerular mesangial cells: dependence on the Fc region of antibody.
The American journal of physiology 1989;257(3 Pt 2):F478-85.
1989: D S Cowen; H M Lazarus; susan shurin; S E Stoll; George R Dubyak
Extracellular adenosine triphosphate activates calcium mobilization in human phagocytic leukocytes and neutrophil/monocyte progenitor cells.
The Journal of clinical investigation 1989;83(5):1651-60.
1989: D Vander Kooy; George R Dubyak; Robert M Moore; John J Moore
Adenosine triphosphate activates the phospholipase-C cascade system in human amnion cells without increasing prostaglandin production.
Endocrinology 1989;124(4):2005-12.
1989: Michael S Simonson; S Wann; P Mené; George R Dubyak; Mark Kester; Y Nakazato; John R Sedor; Michael J Dunn
Endothelin stimulates phospholipase C, Na+/H+ exchange, c-fos expression, and mitogenesis in rat mesangial cells.
The Journal of clinical investigation 1989;83(2):708-12.
1989: Michael S Simonson; S Wann; P Mené; George R Dubyak; Mark Kester; Michael J Dunn
Endothelin-1 activates the phosphoinositide cascade in cultured glomerular mesangial cells.
Journal of cardiovascular pharmacology 1989;13 Suppl 5():S80-3; discussion S84.
1988: George R Dubyak; D S Cowen; L M Meuller
Activation of inositol phospholipid breakdown in HL60 cells by P2-purinergic receptors for extracellular ATP. Evidence for mediation by both pertussis toxin-sensitive and pertussis toxin-insensitive mechanisms.
The Journal of biological chemistry 1988;263(34):18108-17.
1988: P Mené; George R Dubyak; Hanna Abboud; A Scarpa; Michael J Dunn
Phospholipase C activation by prostaglandins and thromboxane A2 in cultured mesangial cells.
The American journal of physiology 1988;255(6 Pt 2):F1059-69.
1988: Michael S Simonson; P Mené; George R Dubyak; Michael J Dunn
Identification and transmembrane signaling of leukotriene D4 receptors in human mesangial cells.
The American journal of physiology 1988;255(6 Pt 1):C771-80.
1988: John J Moore; George R Dubyak; Robert M Moore; D Vander Kooy
Oxytocin activates the inositol-phospholipid-protein kinase-C system and stimulates prostaglandin production in human amnion cells.
Endocrinology 1988;123(4):1771-7.
1988: C Welsh; George R Dubyak; Janice G Douglas
Relationship between phospholipase C activation and prostaglandin E2 and cyclic adenosine monophosphate production in rabbit tubular epithelial cells. Effects of angiotensin, bradykinin, and arginine vasopressin.
The Journal of clinical investigation 1988;81(3):710-9.
1988: D S Cowen; H M Lazarus; George R Dubyak
Flow cytometric measurements of cytosolic [Ca2+] in normal and leukemic progenitor cells.
Annals of the New York Academy of Sciences 1988;551():273-6.
1988: George R Dubyak; D S Cowen; H M Lazarus
Activation of the inositol phospholipid signaling system by receptors for extracellular ATP in human neutrophils, monocytes, and neutrophil/monocyte progenitor cells.
Annals of the New York Academy of Sciences 1988;551():218-37; discussion 237-8.
1987: R G Appel; George R Dubyak; Michael J Dunn
Effect of atrial natriuretic factor on cytosolic free calcium in rat glomerular mesangial cells.
FEBS letters 1987;224(2):396-400.
1987: P Menè; Hanna Abboud; George R Dubyak; A Scarpa; Michael J Dunn
Effects of PDGF on inositol phosphates, Ca2+, and contraction of mesangial cells.
The American journal of physiology 1987;253(3 Pt 2):F458-63.
1987: Mark Kester; P Menè; George R Dubyak; Michael J Dunn
Elevation of cytosolic free calcium by platelet-activating factor in cultured rat mesangial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1987;1(3):215-9.
1987: P Menè; George R Dubyak; Steven N Emancipator; Michael J Dunn
Stimulation of cytosolic free calcium and contraction by immune complexes in cultured rat mesangial cells.
Transactions of the Association of American Physicians 1987;100():179-86.