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Harry Duckworth

Research Profile

Chemicals & Drugs

Living Beings

Escherichia coli

Concepts & Ideas

Physiology

Allosteric Regulation

Genes & Molecular Sequences

Amino Acid Sequences

Procedures

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Circular Dichroism

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Publications

TOP 3
Lynda J Donald; Vladimir M Collado; Jamie J Galka; Joe D O'Neil; Harry W Duckworth; Peter C Loewen; Kenneth G Standing
Urea as a protein destabilizing agent in electrospray ionisation.
Lindsay E Nicolle; Samira Mubareka; Andrew E Simor; B Liu; S McNeil; D Lewis; Harry W Duckworth; Mary Cheang; Mark Loeb
Variation in mortality rates among long-term care facilities for residents with lower respiratory tract infection.
Samira Mubareka; Harry W Duckworth; Mary Cheang; Mark Loeb; Andrew E Simor; Barbara Liu; Shelley McNeil; David Lewis; Lindsay E Nicolle
Use of diagnostic tests for presumed lower respiratory tract infection in long-term care facilities.

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All Publications

2009: Lynda J Donald; Vladimir M Collado; Jamie J Galka; Joe D O'Neil; Harry W Duckworth; Peter C Loewen; Kenneth G Standing
Urea as a protein destabilizing agent in electrospray ionisation.
Rapid communications in mass spectrometry : RCM 2009;23(6):788-92.
2008: Lindsay E Nicolle; Samira Mubareka; Andrew E Simor; B Liu; S McNeil; D Lewis; Harry W Duckworth; Mary Cheang; Mark Loeb
Variation in mortality rates among long-term care facilities for residents with lower respiratory tract infection.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 2008;29(8):754-9.
2007: Samira Mubareka; Harry W Duckworth; Mary Cheang; Mark Loeb; Andrew E Simor; Barbara Liu; Shelley McNeil; David Lewis; Lindsay E Nicolle
Use of diagnostic tests for presumed lower respiratory tract infection in long-term care facilities.
Journal of the American Geriatrics Society 2007;55(9):1365-70.
2006: Arzu Oztürk; Lynda J Donald; Lin Li; Harry W Duckworth; Mary Lynn Duckworth
Proteomic identification of AP2 gamma as a rat placental lactogen II trophoblast cell-specific enhancer binding protein.
Endocrinology 2006;147(9):4319-29.
2006: Kajal Choudhary; Victor Spicer; Lynda J Donald; Harry W Duckworth; Werner Ens; Peter C Loewen; Kenneth G Standing
Method for estimating the isotopic distributions of metabolically labeled proteins by MALDI-TOFMS: application to NMR samples.
Analytical chemistry 2006;78(15):5419-23.
2005: Lynda J Donald; David J Stokell; Neil J Holliday; Werner Ens; Kenneth G Standing; Harry W Duckworth
Multiple equilibria of the Escherichia coli chaperonin GroES revealed by mass spectrometry.
Protein science : a publication of the Protein Society 2005;14(5):1375-9.
2005: Prashen Chelikani; Xavier Carpena; Rosa Perez-Luque; Lynda J Donald; Harry W Duckworth; Jack Switala; Ignacio Fita; Peter C Loewen
Characterization of a large subunit catalase truncated by proteolytic cleavage.
Biochemistry 2005;44(15):5597-605.
2004: Rahul Singh; Ben Wiseman; Taweewat Deemagarn; Lynda J Donald; Harry W Duckworth; Xavier Carpena; Ignacio Fita; Peter C Loewen
Catalase-peroxidases (KatG) exhibit NADH oxidase activity.
The Journal of biological chemistry 2004;279(41):43098-106.
2003: Arzu Oztürk; Agnes Fresnoza; Amanda Savoie; Harry W Duckworth; Mary Lynn Duckworth
Defining regulatory regions in the rat prolactin gene family locus using a large P1 genomic clone.
Endocrinology 2003;144(11):4742-54.
2003: Lynda J Donald; Oleg Krokhin; Harry W Duckworth; Ben Wiseman; Taweewat Deemagarn; Rahul Singh; Jack Switala; Xavier Carpena; Ignacio Fita; Peter C Loewen
Characterization of the catalase-peroxidase KatG from Burkholderia pseudomallei by mass spectrometry.
The Journal of biological chemistry 2003;278(37):35687-92.
2003: David J Stokell; Lynda J Donald; Robert Maurus; Nham T Nguyen; Gillian Sadler; Kajal Choudhary; Philip G Hultin; Gary D Brayer; Harry W Duckworth
Probing the roles of key residues in the unique regulatory NADH binding site of type II citrate synthase of Escherichia coli.
The Journal of biological chemistry 2003;278(37):35435-43.
2003: Prashen Chelikani; Lynda J Donald; Harry W Duckworth; Peter C Loewen
Hydroperoxidase II of Escherichia coli exhibits enhanced resistance to proteolytic cleavage compared to other catalases.
Biochemistry 2003;42(19):5729-35.
2003: Robert Maurus; Nham T Nguyen; David J Stokell; Ayeda Ayed; Philip G Hultin; Harry W Duckworth; Gary D Brayer
Insights into the evolution of allosteric properties. The NADH binding site of hexameric type II citrate synthases.
Biochemistry 2003;42(19):5555-65.
2003: Xavier Carpena; Manuel Soriano; Martin Klotz; Harry W Duckworth; Lynda J Donald; William Melik-Adamyan; Ignacio Fita; Peter C Loewen
Structure of the Clade 1 catalase, CatF of Pseudomonas syringae, at 1.8 A resolution.
Proteins 2003;50(3):423-36.
2001: Nham T Nguyen; Robert Maurus; David J Stokell; Ayeda Ayed; Harry W Duckworth; Gary D Brayer
Comparative analysis of folding and substrate binding sites between regulated hexameric type II citrate synthases and unregulated dimeric type I enzymes.
Biochemistry 2001;40(44):13177-87.
2001: Lynda J Donald; D J Hosfield; S L Cuvelier; Werner Ens; Kenneth G Standing; Harry W Duckworth
Mass spectrometric study of the Escherichia coli repressor proteins, Ic1R and Gc1R, and their complexes with DNA.
Protein science : a publication of the Protein Society 2001;10(7):1370-80.
2000: Darren Manley; ME McComb; Hélène Perreault; Lynda J Donald; Harry W Duckworth; Joe D O'Neil
Secondary structure and oligomerization of the E. coli glycerol facilitator.
Biochemistry 2000;39(40):12303-11.
2000: Sheryl A Zelenitsky; R E Silverman; Harry W Duckworth; Godfrey K M Harding
A prospective, randomized, double-blind studyof single high dose versus multiple standard dose gentamicin both in combination withmetronidazole for colorectal surgicalprophylaxis.
The Journal of hospital infection 2000;46(2):135-40.
2000: AN Krutchinsky; Ayeda Ayed; Lynda J Donald; Werner Ens; Harry W Duckworth; Kenneth G Standing
Studies of noncovalent complexes in an electrospray ionization/time-of-flight mass spectrometer.
Methods in molecular biology (Clifton, N.J.) 2000;146():239-49.
1999: Ayeda Ayed; Harry W Duckworth
A stable intermediate in the equilibrium unfolding of Escherichia coli citrate synthase.
Protein science : a publication of the Protein Society 1999;8(5):1116-26.
1998: Lindsay E Nicolle; Harry W Duckworth; J Brunka; B Urias; J Kennedy; D Murray; Godfrey K M Harding
Urinary antibody level and survival in bacteriuric institutionalized older subjects.
Journal of the American Geriatrics Society 1998;46(8):947-53.
1998: N Potier; Lynda J Donald; IV Chernushevich; Ayeda Ayed; Werner Ens; Cheryl H Arrowsmith; Kenneth G Standing; Harry W Duckworth
Study of a noncovalent trp repressor: DNA operator complex by electrospray ionization time-of-flight mass spectrometry.
Protein science : a publication of the Protein Society 1998;7(6):1388-95.
1998: Ayeda Ayed; AN Krutchinsky; Werner Ens; Kenneth G Standing; Harry W Duckworth
Quantitative evaluation of protein-protein and ligand-protein equilibria of a large allosteric enzyme by electrospray ionization time-of-flight mass spectrometry.
Rapid communications in mass spectrometry : RCM 1998;12(7):339-44.
1996: Pamela Orr; R W Peeling; M Fast; J Brunka; Harry W Duckworth; Godfrey K M Harding; Lindsay E Nicolle
Serological study of responses to selected pathogens causing respiratory tract infection in the institutionalized elderly.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1996;23(6):1240-5.
1996: Lynda J Donald; IV Chernushevich; J Zhou; A Verentchikov; N Poppe-Schriemer; D J Hosfield; J B Westmore; Werner Ens; Harry W Duckworth; Kenneth G Standing
Preparation and properties of pure, full-length IclR protein of Escherichia coli. Use of time-of-flight mass spectrometry to investigate the problems encountered.
Protein science : a publication of the Protein Society 1996;5(8):1613-24.
1996: Pamela Orr; Lindsay E Nicolle; Harry W Duckworth; J Brunka; J Kennedy; D Murray; Godfrey K M Harding
Febrile urinary infection in the institutionalized elderly.
The American journal of medicine 1996;100(1):71-7.
1994: D S Pereira; Lynda J Donald; D J Hosfield; Harry W Duckworth
Active site mutants of Escherichia coli citrate synthase. Effects of mutations on catalytic and allosteric properties.
The Journal of biological chemistry 1994;269(1):412-7.
1994: Lindsay E Nicolle; P Orr; Harry W Duckworth; J Brunka; J Kennedy; B Urias; D Murray; G K Harding
Prospective study of decubitus ulcers in two long term care facilities.
The Canadian journal of infection control : the official journal of the Community & Hospital Infection Control Association-Canada = Revue canadienne de prévention des infections / Association pour la prévention des infections a l'hôpital et dans la communaute-Canada ; CHICA-CANADA 1994;9(2):35-8.
1993: Lindsay E Nicolle; Pamela Orr; Harry W Duckworth; J Brunka; J Kennedy; D Murray; Godfrey K M Harding
Gross hematuria in residents of long-term-care facilities.
The American journal of medicine 1993;94(6):611-8.
1992: G F Molgat; Lynda J Donald; Harry W Duckworth
Chimeric allosteric citrate synthases: construction and properties of citrate synthases containing domains from two different enzymes.
Archives of biochemistry and biophysics 1992;298(1):238-46.
1992: Linda C Kurz; S Shah; B R Crane; Lynda J Donald; Harry W Duckworth; G R Drysdale
Proton uptake accompanies formation of the ternary complex of citrate synthase, oxaloacetate, and the transition-state analog inhibitor, carboxymethyl-CoA. Evidence that a neutral enol is the activated form of acetyl-CoA in the citrate synthase reaction.
Biochemistry 1992;31(34):7899-907.
1991: Lynda J Donald; B R Crane; D H Anderson; Harry W Duckworth
The role of cysteine 206 in allosteric inhibition of Escherichia coli citrate synthase. Studies by chemical modification, site-directed mutagenesis, and 19F NMR.
The Journal of biological chemistry 1991;266(31):20709-13.
1991: D H Anderson; Lynda J Donald; M V Jacob; Harry W Duckworth
A mutant of Escherichia coli citrate synthase that affects the allosteric equilibrium.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1991;69(4):232-8.
1989: Lynda J Donald; G F Molgat; Harry W Duckworth
Cloning, sequencing, and expression of the gene for NADH-sensitive citrate synthase of Pseudomonas aeruginosa.
Journal of bacteriology 1989;171(10):5542-50.
1989: D H Anderson; Harry W Duckworth
Mutation of amino acids thought to polarize the oxaloacetate carbonyl in citrate synthase severely reduces but does not abolish activity of the enzyme.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1989;67(2-3):98-102.
1988: D H Anderson; Harry W Duckworth
In vitro mutagenesis of Escherichia coli citrate synthase to clarify the locations of ligand binding sites.
The Journal of biological chemistry 1988;263(5):2163-9.
1987: Lynda J Donald; Harry W Duckworth
Expression and base sequence of the citrate synthase gene of Acinetobacter anitratum.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1987;65(11):930-8.
1987: Harry W Duckworth; D H Anderson; Alexander (Alex) Bell; Lynda J Donald; A L Chu; G D Brayer
Structural basis for regulation in gram-negative bacterial citrate synthases.
Biochemical Society symposium 1987;54():83-92.
1986: Lynda J Donald; Harry W Duckworth
Molecular cloning of the structural gene for Acinetobacter citrate synthase.
Biochemical and biophysical research communications 1986;141(2):797-803.