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Anette Duensing

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TOP 3
Anette Duensing
Closing in on accurate risk prediction and disease management for patients with operable GIST.
Nina Korzeniewski; Nicole Spardy; Anette Duensing; Stefan Duensing
Genomic instability and cancer: lessons learned from human papillomaviruses.
Nina Korzeniewski; Rolando Cuevas; Anette Duensing; Stefan Duensing
Daughter centriole elongation is controlled by proteolysis.

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All Publications

2012: Anette Duensing
Closing in on accurate risk prediction and disease management for patients with operable GIST.
The lancet oncology 2012;13(3):220-1.
2011: Nina Korzeniewski; Nicole Spardy; Anette Duensing; Stefan Duensing
Genomic instability and cancer: lessons learned from human papillomaviruses.
Cancer letters 2011;305(2):113-22.
2010: Nina Korzeniewski; Rolando Cuevas; Anette Duensing; Stefan Duensing
Daughter centriole elongation is controlled by proteolysis.
Molecular biology of the cell 2010;21(22):3942-51.
2010: Stefan Duensing; Nadja Melquiot; Anthony Brickner; Rolando Cuevas; Sebastian Darr; Anette Duensing; Karl Münger
Tripeptidyl Peptidase II Is Required for c-MYC-Induced Centriole Overduplication and a Novel Therapeutic Target in c-MYC-Associated Neoplasms.
Genes & cancer 2010;1(9):883-92.
2010: Stefan Duensing; Anette Duensing
Targeted therapies of gastrointestinal stromal tumors (GIST)--the next frontiers.
Biochemical pharmacology 2010;80(5):575-83.
2010: Stefan Duensing; Anette Duensing
Bortezomib: killing two birds with one stone in gastrointestinal stromal tumors.
Oncotarget 2010;1(1):6-8.
2010: Anette Duensing; Stefan Duensing
Centrosomes, polyploidy and cancer.
Advances in experimental medicine and biology 2010;676():93-103.
2010: Nina Korzeniewski; Sarah Wheeler; Payel Chatterjee; Anette Duensing; Stefan Duensing
A novel role of the aryl hydrocarbon receptor (AhR) in centrosome amplification - implications for chemoprevention.
Molecular cancer 2010;9():153.
2009: Anette Duensing; Nicole Spardy; Payel Chatterjee; Leon Zheng; Joshua Parry; Rolando Cuevas; Nina Korzeniewski; Stefan Duensing
Centrosome overduplication, chromosomal instability, and human papillomavirus oncoproteins.
Environmental and molecular mutagenesis 2009;50(8):741-7.
2009: Nicole Spardy; Kathryn Covella; Elliot Cha; Elizabeth E Hoskins; Susanne I Wells; Anette Duensing; Stefan Duensing
Human papillomavirus 16 E7 oncoprotein attenuates DNA damage checkpoint control by increasing the proteolytic turnover of claspin.
Cancer research 2009;69(17):7022-9.
2009: Nina Korzeniewski; Leon Zheng; Rolando Cuevas; Joshua Parry; Payel Chatterjee; Brittany Anderton; Anette Duensing; Karl Münger; Stefan Duensing
Cullin 1 functions as a centrosomal suppressor of centriole multiplication by regulating polo-like kinase 4 protein levels.
Cancer research 2009;69(16):6668-75.
2008: Nicole Spardy; Anette Duensing; Elizabeth E Hoskins; Susanne I Wells; Stefan Duensing
HPV-16 E7 reveals a link between DNA replication stress, fanconi anemia D2 protein, and alternative lengthening of telomere-associated promyelocytic leukemia bodies.
Cancer research 2008;68(23):9954-63.
2008: Ying Liu; Sophie A Perdreau; Payel Chatterjee; Linan Wang; Shih-Fan Kuan; Anette Duensing
Imatinib mesylate induces quiescence in gastrointestinal stromal tumor cells through the CDH1-SKP2-p27Kip1 signaling axis.
Cancer research 2008;68(21):9015-23.
2008: Anwaar Ahmad; Andria Rasile Robinson; Anette Duensing; Ellen van Drunen; Berna Beverloo; David B Weisberg; Edward Hasty; Jan H J Hoeijmakers; Laura J Niedernhofer
ERCC1-XPF endonuclease facilitates DNA double-strand break repair.
Molecular and cellular biology 2008;28(16):5082-92.
2008: Anette Duensing; Anna Chin; Linan Wang; Shih-Fan Kuan; Stefan Duensing
Analysis of centrosome overduplication in correlation to cell division errors in high-risk human papillomavirus (HPV)-associated anal neoplasms.
Virology 2008;372(1):157-64.
2008: Ying Liu; Joshua A Parry; Anna Chin; Stefan Duensing; Anette Duensing
Soluble histone H2AX is induced by DNA replication stress and sensitizes cells to undergo apoptosis.
Molecular cancer 2008;7():61.
2008: Anette Duensing; Stefan Duensing
Centrosome-mediated chromosomal instability and steroid hormones as co factors in human papillomavirus-associated cervical carcinogenesis: small viruses help to answer big questions.
Advances in experimental medicine and biology 2008;617():109-17.
2007: Nicole Spardy; Anette Duensing; Domonique Charles; Nathan Haines; Tomomi Nakahara; Paul F Lambert; Stefan Duensing
The human papillomavirus type 16 E7 oncoprotein activates the Fanconi anemia (FA) pathway and causes accelerated chromosomal instability in FA cells.
Journal of virology 2007;81(23):13265-70.
2007: S Bauer; Anette Duensing; George D Demetri; Jonathan A Fletcher
KIT oncogenic signaling mechanisms in imatinib-resistant gastrointestinal stromal tumor: PI3-kinase/AKT is a crucial survival pathway.
Oncogene 2007;26(54):7560-8.
2007: Anette Duensing; Youhua Liu; S A Perdreau; Julia Kleylein-Sohn; Erich A Nigg; Stefan Duensing
Centriole overduplication through the concurrent formation of multiple daughter centrioles at single maternal templates.
Oncogene 2007;26(43):6280-8.
2007: Ying Liu; Michelle Tseng; Sophie A Perdreau; Ferdinand Rossi; Cristina R Antonescu; Peter Besmer; Jonathan A Fletcher; Stefan Duensing; Anette Duensing
Histone H2AX is a mediator of gastrointestinal stromal tumor cell apoptosis following treatment with imatinib mesylate.
Cancer research 2007;67(6):2685-92.
2007: Anette Duensing; Youhua Liu; Nicole Spardy; K Bartoli; Michelle Tseng; J-A Kwon; X Teng; Stefan Duensing
RNA polymerase II transcription is required for human papillomavirus type 16 E7- and hydroxyurea-induced centriole overduplication.
Oncogene 2007;26(2):215-23.
2006: Anette Duensing; Louis Ghanem; Richard A Steinman; Ying Liu; Stefan Duensing
p21(Waf1/Cip1) deficiency stimulates centriole overduplication.
Cell cycle (Georgetown, Tex.) 2006;5(24):2899-902.
2006: Anette Duensing; Xiaoyi Teng; Ying Liu; Michelle Tseng; Nicole Spardy; Stefan Duensing
A role of the mitotic spindle checkpoint in the cellular response to DNA replication stress.
Journal of cellular biochemistry 2006;99(3):759-69.
2006: Brian P Rubin; Anette Duensing
Mechanisms of resistance to small molecule kinase inhibition in the treatment of solid tumors.
Laboratory investigation; a journal of technical methods and pathology 2006;86(10):981-6.
2006: Anette Duensing; Youhua Liu; Michelle Tseng; Marcos Malumbres; Mariano Barbacid; Stefan Duensing
Cyclin-dependent kinase 2 is dispensable for normal centrosome duplication but required for oncogene-induced centrosome overduplication.
Oncogene 2006;25(20):2943-9.
2006: Karl Münger; Hiroyuki Hayakawa; Christine L Nguyen; Nadja V Melquiot; Anette Duensing; Stefan Duensing
Viral carcinogenesis and genomic instability.
EXS 2006;(96):179-99.
2005: Anette Duensing; Stefan Duensing
Guilt by association? p53 and the development of aneuploidy in cancer.
Biochemical and biophysical research communications 2005;331(3):694-700.
2005: Frederick P Li; Jonathan A Fletcher; Michael C Heinrich; Judy E Garber; Stephen E Sallan; Clara Curiel-Lewandrowski; Anette Duensing; Matt van de Rijn; Lowell E Schnipper; George D Demetri
Familial gastrointestinal stromal tumor syndrome: phenotypic and molecular features in a kindred.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(12):2735-43.
2004: Stefan Duensing; Anette Duensing; David C Lee; Kirsten M Edwards; Siribang-On Piboonniyom; Edwin Manuel; Leandros Skaltsounis; Laurent Meijer; Karl Münger
Cyclin-dependent kinase inhibitor indirubin-3'-oxime selectively inhibits human papillomavirus type 16 E7-induced numerical centrosome anomalies.
Oncogene 2004;23(50):8206-15.
2004: Anette Duensing; Nora E Joseph; Fabiola Medeiros; Felicity Smith; Jason L Hornick; Michael C Heinrich; Christopher L Corless; George D Demetri; Christopher D M Fletcher; Jonathan A Fletcher
Protein Kinase C theta (PKCtheta) expression and constitutive activation in gastrointestinal stromal tumors (GISTs).
Cancer research 2004;64(15):5127-31.
2004: Fabiola Medeiros; Christopher L Corless; Anette Duensing; Jason L Hornick; Andre M Oliveira; Michael C Heinrich; Jonathan A Fletcher; Christopher D M Fletcher
KIT-negative gastrointestinal stromal tumors: proof of concept and therapeutic implications.
The American journal of surgical pathology 2004;28(7):889-94.
2004: Anette Duensing; Fabiola Medeiros; Bryna McConarty; Nora E Joseph; Dipak Panigrahy; Samuel Singer; Christopher D M Fletcher; George D Demetri; Jonathan A Fletcher
Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs).
Oncogene 2004;23(22):3999-4006.
2004: Anette Duensing; Michael C Heinrich; Christopher D Fletcher; Jonathan A Fletcher
Biology of gastrointestinal stromal tumors: KIT mutations and beyond.
Cancer investigation 2004;22(1):106-16.
2003: Guntram Buesche; Axel Georgii; Anette Duensing; Anita Schmeil; Jerome Schlue; Hans H Kreipe
Evaluating the volume ratio of bone marrow affected by fibrosis: a parameter crucial for the prognostic significance of marrow fibrosis in chronic myeloid leukemia.
Human pathology 2003;34(4):391-401.
2003: Michael C Heinrich; Christopher L Corless; Anette Duensing; Laura McGreevey; Chang-Jie Chen; Nora E Joseph; Samuel Singer; Diana J Griffith; Andrea Haley; Ajia Town; George D Demetri; Christopher D M Fletcher; Jonathan A Fletcher
PDGFRA activating mutations in gastrointestinal stromal tumors.
Science (New York, N.Y.) 2003;299(5607):708-10.
2001: Brian P Rubin; Samuel Singer; C Tsao; Anette Duensing; Marcia L Lux; R Ruiz; MK Hibbard; Chang-Jie Chen; Sheng Xiao; D A Tuveson; George D Demetri; Christopher D M Fletcher; Jonathan A Fletcher
KIT activation is a ubiquitous feature of gastrointestinal stromal tumors.
Cancer research 2001;61(22):8118-21.
2001: Stefan Duensing; Anette Duensing; Elsa R Flores; A Do; Paul F Lambert; Karl Münger
Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes.
Journal of virology 2001;75(16):7712-6.
2001: Stefan Duensing; Anette Duensing; Christopher P Crum; Karl Münger
Human papillomavirus type 16 E7 oncoprotein-induced abnormal centrosome synthesis is an early event in the evolving malignant phenotype.
Cancer research 2001;61(6):2356-60.
2000: Stefan Duensing; L Y Lee; Anette Duensing; John Basile; Siribang-On Piboonniyom; S Gonzalez; Christopher P Crum; K Munger
The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(18):10002-7.
1999: Stefan Duensing; Anette Duensing; Johannes Gobertus Meran; Andreas Kreft; Guntram Büsche; Arnold Ganser; Axel Georgii
Molecular detection of c-mpl thrombopoietin receptor gene expression in chronic myeloproliferative disorders.
Molecular pathology : MP 1999;52(3):146-50.
1999: Reinhard Hoffmann; Anke Franzke; Jan Buer; Saadettin Sel; K Oevermann; Anette Duensing; M Probst; Stefan Duensing; Holger Kirchner; Arnold Ganser; Jens Atzpodien
Prognostic impact of in vivo soluble cell adhesion molecules in metastatic renal cell carcinoma.
British journal of cancer 1999;79(11-12):1742-5.
1998: Stefan Duensing; Anette Duensing; Jens Grosse; Jens Atzpodien
Loss of VLA-3 (CD49c/CD29) expression in two multidrug resistant Burkitt's lymphoma cell lines.
Cancer biotherapy & radiopharmaceuticals 1998;13(5):369-73.