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Richard Duerr

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Mark Lazarev; Dermot P McGovern; Deborah D Proctor; Miguel Regueiro; John D Rioux; Philip P Schumm; Mark S Silverberg; A Hillary Steinhart; Kent D Taylor; Judy H Cho; Richard H Duerr; Chengrui Huang; Susan Hutfless; Alain Bitton; Steven R Brant
Relationship between proximal Crohn's disease location and disease behavior and surgery: a cross-sectional study of the IBD Genetics Consortium.
Ming-Hsien Wang; Yuqiong Wu; Judy H Cho; C Cuffari; Themistocles Dassopoulos; Lisa Datta; Richard H Duerr; Jean G Ford; Mary L Harris; Stanley Hooker; Kim L Isaacs; Howard Kader; Linda W H Kao; Rick A Kittles; Subra Kugathasan; James D Lewis; Geoffrey C Nguyen; Toshihiko Okazaki; Maria Oliva-Hemker; John D Rioux; Mark S Silverberg; DUANE SMOOT; Kent D Taylor; Michael Torbenson; John Valentine; Steven R Brant
Contribution of higher risk genes and European admixture to Crohn's disease in African Americans.
Aleixo Muise; Ryan Murchie; Andrew D Paterson; Richard K Russell; Jack Satsangi; Mary Sherlock; Mark S Silverberg; Thomas D Walters; David C Wilson; Victorien M Wolters; Wei Xu; Judy H Cho; Richard H Duerr; Ramzi Fattouh; Juan Cristóbal Gana; Michael Glogauer; Anne M Griffiths; Cong-Hui Guo; Pingzhao Hu; Grace Y Lam; Charles W Lees; John H Brumell
NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2.

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All Publications

2013: Mark Lazarev; Dermot P McGovern; Deborah D Proctor; Miguel Regueiro; John D Rioux; Philip P Schumm; Mark S Silverberg; A Hillary Steinhart; Kent D Taylor; Judy H Cho; Richard H Duerr; Chengrui Huang; Susan Hutfless; Alain Bitton; Steven R Brant
Relationship between proximal Crohn's disease location and disease behavior and surgery: a cross-sectional study of the IBD Genetics Consortium.
The American journal of gastroenterology 2013;108(1):106-12.
2012: Ming-Hsien Wang; Yuqiong Wu; Judy H Cho; C Cuffari; Themistocles Dassopoulos; Lisa Datta; Richard H Duerr; Jean G Ford; Mary L Harris; Stanley Hooker; Kim L Isaacs; Howard Kader; Linda W H Kao; Rick A Kittles; Subra Kugathasan; James D Lewis; Geoffrey C Nguyen; Toshihiko Okazaki; Maria Oliva-Hemker; John D Rioux; Mark S Silverberg; DUANE SMOOT; Kent D Taylor; Michael Torbenson; John Valentine; Steven R Brant
Contribution of higher risk genes and European admixture to Crohn's disease in African Americans.
Inflammatory bowel diseases 2012;18(12):2277-87.
2012: Aleixo Muise; Ryan Murchie; Andrew D Paterson; Richard K Russell; Jack Satsangi; Mary Sherlock; Mark S Silverberg; Thomas D Walters; David C Wilson; Victorien M Wolters; Wei Xu; Judy H Cho; Richard H Duerr; Ramzi Fattouh; Juan Cristóbal Gana; Michael Glogauer; Anne M Griffiths; Cong-Hui Guo; Pingzhao Hu; Grace Y Lam; Charles W Lees; John H Brumell
NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2.
Gut 2012;61(7):1028-35.
2012: J-P Achkar; G Bellone; A Brzezinski; B Devlin; C Fiocchi; M I Kamboh; Linda R Klei; Y Lu; N Rebert; M Regueiro; Steven Ringquist; K Roeder; R Scott; M Trucco; P I W de Bakker; Richard H Duerr
Amino acid position 11 of HLA-DRβ1 is a major determinant of chromosome 6p association with ulcerative colitis.
Genes and immunity 2012;13(3):245-52.
2011: Arthur Barrie; Richard H Duerr; Matthew Henkel; Anupriya Khare; M. Michael Barmada; Yingze Zhang; Anuradha Ray
Prostaglandin E2 and IL-23 plus IL-1β differentially regulate the Th1/Th17 immune response of human CD161(+) CD4(+) memory T cells.
Clinical and translational science 2011;4(4):268-73.
2011: Aleixo Muise; Bo-Yee Ngan; Andrew D Paterson; Paul Renbaum; Jack Satsangi; Grace Shen-Tu; Philip M Sherman; Mark S Silverberg; Dan Turner; Johan Van Limbergen; Thomas Walters; David C Wilson; Victorien M Wolters; Wei Xu; Judy Cho; Lee A Denson; Richard H Duerr; Ramzi Fattouh; Michael Glogauer; Anne M Griffiths; Cong-Hui Guo; Yair Kasirer; Grace Y Lam; Charlie W Lees; Joshua Bennitz; John H Brumell
Single nucleotide polymorphisms that increase expression of the guanosine triphosphatase RAC1 are associated with ulcerative colitis.
Gastroenterology 2011;141(2):633-41.
2011: Mylarappa Ningappa; Brandon W Higgs; Daniel E Weeks; Chethan Ashokkumar; Richard H Duerr; Qing Sun; Kyle Soltys; Geoffrey J Bond; Kareem Abu-Elmagd; George V Mazariegos; Feras Alissa; Marcus Rivera; Jeffrey Rudolph; Robert Squires; Hakon Hakonarson; Rakesh Sindhi
NOD2 gene polymorphism rs2066844 associates with need for combined liver-intestine transplantation in children with short-gut syndrome.
The American journal of gastroenterology 2011;106(1):157-65.
2009: E A M Festen; Philippe Goyette; R Scott; V Annese; Alexandra Zhernakova; J Lian; C Lefèbvre; Steven R Brant; Judy H Cho; Mark S Silverberg; Kent D Taylor; Dirk J de Jong; Pieter C F Stokkers; D Mcgovern; O Palmieri; J-P Achkar; Ramnik Xavier; Mark J Daly; Richard H Duerr; Cisca Wijmenga; Rinse Weersma; John D Rioux
Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis.
Gut 2009;58(6):799-804.
2008: C Labbé; Philippe Goyette; C Lefebvre; C Stevens; T Green; M K Tello-Ruiz; Z Cao; A L Landry; J Stempak; V Annese; A Latiano; Steven R Brant; Richard H Duerr; K D Taylor; Judy H Cho; A Hillary Steinhart; Mark J Daly; Mark S Silverberg; Ramnik Xavier; John D Rioux
MAST3: a novel IBD risk factor that modulates TLR4 signaling.
Genes and immunity 2008;9(7):602-12.
2007: Themistocles Dassopoulos; Geoffrey C Nguyen; Alain Bitton; Gillian P Bromfield; L Philip Schumm; Yahong Wu; Abdul Elkadri; Miguel Regueiro; Benjamin Siemanowski; Esther A Torres; Federico J Gregory; Sunanda V Kane; Laura E Harrell; Denis Franchimont; Jean-Paul Achkar; Anne Griffiths; Steven R Brant; John D Rioux; Kent D Taylor; Richard H Duerr; Mark S Silverberg; Judy H Cho; A Hillary Steinhart
Assessment of reliability and validity of IBD phenotyping within the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium (IBDGC).
Inflammatory bowel diseases 2007;13(8):975-83.
2007: Aleixo Muise; Thomas D Walters; Eytan Wine; Anne M Griffiths; Dan Turner; Richard H Duerr; Miguel Regueiro; Bo-Yee Ngan; Wei Xu; Philip M Sherman; Mark S Silverberg; Daniela Rotin
Protein-tyrosine phosphatase sigma is associated with ulcerative colitis.
Current biology : CB 2007;17(14):1212-8.
2007: Philip De Jager; Denis Franchimont; Alicja Waliszewska; Alain Bitton; Albert Cohen; Diane Langelier; J Belaiche; Severine Vermeire; Lisa Farwell; An Goris; Cecile Libioulle; NIRAJ JANI; Themistocles Dassopoulos; Gillian P Bromfield; Bruno Dubois; J H Cho; Steven R Brant; Richard H Duerr; Haifeng Yang; J I Rotter; M S Silverberg; A Hillary Steinhart; Mark J Daly; Daniel K Podolsky; E Louis; David A Hafler; John D Rioux
The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases.
Genes and immunity 2007;8(5):387-97.
2007: Guo-Zhong Tao; Pavel Strnad; Qin Zhou; Ahmad Kamal; Leilei Zhang; Nahid D Madani; Subra Kugathasan; Steven R Brant; Judy H Cho; Bishr Omary; Richard H Duerr
Analysis of keratin polypeptides 8 and 19 variants in inflammatory bowel disease.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2007;5(7):857-64.
2007: John D Rioux; Ramnik Xavier; Kent D Taylor; Mark S Silverberg; Philippe Goyette; Alan Huett; Todd Green; Petric Kuballa; M. Michael Barmada; Lisa Datta; Yin Yao Shugart; Anne M Griffiths; Stephan R Targan; Andrew Ippoliti; Edmond-Jean Bernard; Ling Mei; Dan L Nicolae; Miguel Regueiro; L Philip Schumm; A Hillary Steinhart; Jerome I Rotter; Richard H Duerr; Judy H Cho; Mark J Daly; Steven R Brant
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.
Nature genetics 2007;39(5):596-604.
2007: Mark S Silverberg; Richard H Duerr; Steven R Brant; Gillian P Bromfield; Lisa Datta; NIRAJ JANI; Sunanda V Kane; Jerome I Rotter; L Philip Schumm; A Hillary Steinhart; Kent D Taylor; Huiying Yang; Judy H Cho; John D Rioux; Mark J Daly
Refined genomic localization and ethnic differences observed for the IBD5 association with Crohn's disease.
European journal of human genetics : EJHG 2007;15(3):328-35.
2006: Richard H Duerr; Kent D Taylor; Steven R Brant; John D Rioux; Mark S Silverberg; Mark J Daly; A Hillary Steinhart; Clara Abraham; Miguel Regueiro; Anne Griffiths; Themistocles Dassopoulos; Alain Bitton; Huiying Yang; Stephan R Targan; Lisa Datta; Emily O Kistner; L Philip Schumm; Annette T Lee; Peter K Gregersen; M. Michael Barmada; Jerome I Rotter; Dan L Nicolae; Judy H Cho
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.
Science (New York, N.Y.) 2006;314(5804):1461-3.
2006: Carolien I Panhuysen; Amir Karban; Alisa Knodle Manning; Theodore M Bayless; Richard H Duerr; Joan E Bailey-Wilson; Ervin H Epstein; Steven R Brant
Identification of genetic loci for basal cell nevus syndrome and inflammatory bowel disease in a single large pedigree.
Human genetics 2006;120(1):31-41.
2006: Andrew T Gewirtz; Matam Vijay-Kumar; Steven R Brant; Richard H Duerr; Dan L Nicolae; Judy H Cho
Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease.
American journal of physiology. Gastrointestinal and liver physiology 2006;290(6):G1157-63.
2006: Geoffrey C Nguyen; Esther A Torres; Miguel Regueiro; Gillian P Bromfield; Alain Bitton; Joanne Stempak; Themistocles Dassopoulos; Philip Schumm; Federico J Gregory; Anne M Griffiths; Stephen B Hanauer; Jennifer Hanson; Mary L Harris; Sunanda V Kane; Heather Kiraly Orkwis; Raymond Lahaie; Maria Oliva-Hemker; Pierre Pare; Gary E Wild; John D Rioux; Huiying Yang; Richard H Duerr; Judy H Cho; A Hillary Steinhart; Steven R Brant; Mark S Silverberg
Inflammatory bowel disease characteristics among African Americans, Hispanics, and non-Hispanic Whites: characterization of a large North American cohort.
The American journal of gastroenterology 2006;101(5):1012-23.
2006: Jean-Paul Achkar; Themistocles Dassopoulos; Mark S Silverberg; Jeffrey A Tuvlin; Richard H Duerr; Steven R Brant; Katherine A Siminovitch; Deepa Reddy; Lisa Datta; Theodore M Bayless; Leilei Zhang; M. Michael Barmada; John D Rioux; A Hillary Steinhart; Robin S McLeod; Anne M Griffiths; Zane Cohen; Huiying Yang; Gillian P Bromfield; Phil Schumm; Stephen B Hanauer; Judy H Cho; Dan L Nicolae
Phenotype-stratified genetic linkage study demonstrates that IBD2 is an extensive ulcerative colitis locus.
The American journal of gastroenterology 2006;101(3):572-80.
2005: Carmen B Meier; Refaat A F Hegazi; James Aisenberg; Peter Legnani; Naris Nilubol; Gena M Cobrin; Richard H Duerr; Stephen R Gorfine; Joel J Bauer; David B Sachar; Scott Plevy
Innate immune receptor genetic polymorphisms in pouchitis: is CARD15 a susceptibility factor?
Inflammatory bowel diseases 2005;11(11):965-71.
2005: Marie Pierik; Huiying Yang; M. Michael Barmada; Juleen A Cavanaugh; Vito Annese; Steven R Brant; Judy H Cho; Richard H Duerr; Jean-Pierre Hugot; Dermot P B McGovern; Paulina Paavola-Sakki; Graham Radford-Smith; P Pavli; Mark S Silverberg; Stephan Schreiber; Kent D Taylor; Robert Francois Vlietinck
The IBD international genetics consortium provides further evidence for linkage to IBD4 and shows gene-environment interaction.
Inflammatory bowel diseases 2005;11(1):1-7.
2004: M. Michael Barmada; Steven R Brant; Dan L Nicolae; Jean-Paul Achkar; Carolien I Panhuysen; Theodore M Bayless; Judy H Cho; Richard H Duerr
A genome scan in 260 inflammatory bowel disease-affected relative pairs.
Inflammatory bowel diseases 2004;10(5):513-20.
2004: M. Michael Barmada; Steven R Brant; Dan L Nicolae; Jean-Paul Achkar; Carolien I Panhuysen; Theodore M Bayless; Judy H Cho; Richard H Duerr
A genome scan in 260 inflammatory bowel disease-affected relative pairs.
Inflammatory bowel diseases 2004;10(1):15-22.
2004: Amir Karban; Toshihiko Okazaki; Carolien I Panhuysen; Thomas Gallegos; James J Potter; Joan E Bailey-Wilson; Mark S Silverberg; Richard H Duerr; Judy H Cho; Peter K Gregersen; Yuqiong Wu; Jean-Paul Achkar; Themistocles Dassopoulos; Esteban Mezey; Theodore M Bayless; Franklin J Nouvet; Steven R Brant
Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis.
Human molecular genetics 2004;13(1):35-45.
2003: Steven R Brant; Carolien I Panhuysen; Dan L Nicolae; Deepthi M Reddy; Denise K Bonen; Reda Karaliukas; Leilei Zhang; Eric Swanson; Lisa Datta; Thomas Moran; Geoffrey Ravenhill; Richard H Duerr; Jean-Paul Achkar; Amir Karban; Judy H Cho
MDR1 Ala893 polymorphism is associated with inflammatory bowel disease.
American journal of human genetics 2003;73(6):1282-92.
2003: Richard H Duerr
Update on the genetics of inflammatory bowel disease.
Journal of clinical gastroenterology 2003;37(5):358-67.
2003: Steven R Brant; Michael F Picco; Jean-Paul Achkar; Theodore M Bayless; Sunanda V Kane; Aaron Brzezinski; Franklin J Nouvet; Denise K Bonen; Amir Karban; Themistocles Dassopoulos; Reda Karaliukas; Terri H beaty; Stephen B Hanauer; Richard H Duerr; Judy H Cho
Defining complex contributions of NOD2/CARD15 gene mutations, age at onset, and tobacco use on Crohn's disease phenotypes.
Inflammatory bowel diseases 2003;9(5):281-9.
2003: Denise K Bonen; Yasunori Ogura; Dan L Nicolae; Naohiro Inohara; Lisa Saab; Tsuyoshi Tanabe; Felicia F Chen; Simon J Foster; Richard H Duerr; Steven R Brant; Judy H Cho; Gabriel Nuñez
Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan.
Gastroenterology 2003;124(1):140-6.
2002: Richard H Duerr; M. Michael Barmada; Leilei Zhang; Jean-Paul Achkar; Judy H Cho; Stephen B Hanauer; Steven R Brant; Theodore M Bayless; Robert N Baldassano; Daniel E Weeks
Evidence for an inflammatory bowel disease locus on chromosome 3p26: linkage, transmission/disequilibrium and partitioning of linkage.
Human molecular genetics 2002;11(21):2599-606.
2002: Jean-Paul Achkar; M. Michael Barmada; Richard H Duerr
Perinuclear neutrophil antibodies are not markers for genetic susceptibility or indicators of genetic heterogeneity in familial ulcerative colitis.
The American journal of gastroenterology 2002;97(9):2343-9.
2002: Michael A Eberle; Roland H Pfützer; Kay L Pogue-Geile; Mary P Bronner; David A Crispin; Michael B Kimmey; Richard H Duerr; Leonid Kruglyak; david whitcomb; Teresa A Brentnall
A new susceptibility locus for autosomal dominant pancreatic cancer maps to chromosome 4q32-34.
American journal of human genetics 2002;70(4):1044-8.
2002: Richard H Duerr
The genetics of inflammatory bowel disease.
Gastroenterology clinics of North America 2002;31(1):63-76.
2001: M Parkes; J Satsangi; Derek P Jewell; Daniel E Weeks; M. Michael Barmada; Richard H Duerr
Ulcerative colitis is more strongly linked to chromosome 12 than Crohn's disease.
Gut 2001;49(2):311.
2001: Yasunori Ogura; Denise K Bonen; Naohiro Inohara; Dan L Nicolae; Felicia F Chen; R Ramos; H Britton; Thomas Moran; R Karaliuskas; Richard H Duerr; Jean-Paul Achkar; Steven R Brant; Theodore M Bayless; Barbara S Kirschner; Stephen B Hanauer; Gabriel Nuñez; Judy H Cho
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease.
Nature 2001;411(6837):603-6.
2000: M Parkes; M. Michael Barmada; J Satsangi; Daniel E Weeks; Derek P Jewell; Richard H Duerr
The IBD2 locus shows linkage heterogeneity between ulcerative colitis and Crohn disease.
American journal of human genetics 2000;67(6):1605-10.
2000: Richard H Duerr; M. Michael Barmada; L Zhang; Roland H Pfützer; Daniel E Weeks
High-density genome scan in Crohn disease shows confirmed linkage to chromosome 14q11-12.
American journal of human genetics 2000;66(6):1857-62.
1998: Richard H Duerr; M. Michael Barmada; L Zhang; S Davis; Robert A Preston; L J Chensny; J L Brown; Garth D Ehrlich; Daniel E Weeks; Christopher E Aston
Linkage and association between inflammatory bowel disease and a locus on chromosome 12.
American journal of human genetics 1998;63(1):95-100.
1996: Richard H Duerr
Genetics of inflammatory bowel disease.
Inflammatory bowel diseases 1996;2(1):48-60.
1995: M A Peppercorn; Richard H Duerr
Is there a genetic basis for clinical subsets of ulcerative colitis?
Inflammatory bowel diseases 1995;1(3):234-5.