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Rodger Duffin

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Ken Donaldson; Rodger Duffin; Jeremy P Langrish; Mark R Miller; Nicholas L Mills; Craig A Poland; Jennifer Raftis; Anoop Shah; Catherine A Shaw; David E Newby
Nanoparticles and the cardiovascular system: a critical review.
Christopher D Lucas; John A Marwick; Lauren A Melrose; Keith C Allen; David A Dorward; Rodger Duffin; Christopher Haslett; Laura J Hoodless; Carl S Tucker; Adriano G Rossi
Flavones induce neutrophil apoptosis by down-regulation of Mcl-1 via a proteasomal-dependent pathway.
Craig A Poland; Adriele Prina Mello; Yuri Volkov; Rodger Duffin; Yurii Gounko; Fiona A Murphy; Fiona Byrne; Wan-Seob Cho; J M D Coey; Gemma Louise Davies; Ken Donaldson
Length-dependent pathogenic effects of nickel nanowires in the lungs and the peritoneal cavity.

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All Publications

2013: Ken Donaldson; Rodger Duffin; Jeremy P Langrish; Mark R Miller; Nicholas L Mills; Craig A Poland; Jennifer Raftis; Anoop Shah; Catherine A Shaw; David E Newby
Nanoparticles and the cardiovascular system: a critical review.
Nanomedicine (London, England) 2013;8(3):403-23.
2013: Christopher D Lucas; John A Marwick; Lauren A Melrose; Keith C Allen; David A Dorward; Rodger Duffin; Christopher Haslett; Laura J Hoodless; Carl S Tucker; Adriano G Rossi
Flavones induce neutrophil apoptosis by down-regulation of Mcl-1 via a proteasomal-dependent pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013;27(3):1084-94.
2012: Craig A Poland; Adriele Prina Mello; Yuri Volkov; Rodger Duffin; Yurii Gounko; Fiona A Murphy; Fiona Byrne; Wan-Seob Cho; J M D Coey; Gemma Louise Davies; Ken Donaldson
Length-dependent pathogenic effects of nickel nanowires in the lungs and the peritoneal cavity.
Nanotoxicology 2012;6():899-911.
2012: Kevin Dhaliwal; David A Dorward; Rodger Duffin; David Ferenbach; Michael Gibbons; Christopher Haslett; Nik Hirani; Jeremy Hughes; Duncan Humphries; Matthias Mack; Alison MacKinnon; Andrew Conway Morris; Adriano G Rossi; Emma Scholefield; Nico van Rooijen; William A H Wallace; Tom S Wilkinson; Donald J Davidson; A John Simpson
Monocytes control second-phase neutrophil emigration in established lipopolysaccharide-induced murine lung injury.
American journal of respiratory and critical care medicine 2012;186(6):514-24.
2012: Mairi Brittan; Andrew Conway Morris; Kev Dhaliwal; Rodger Duffin; Christopher Haslett; Nik Hirani; Shonna Johnston; Danny F McAuley; Graham Monro; Adriano G Rossi; Fiona Rossi; Niall Anderson; Laura Barr; A John Simpson
A novel subpopulation of monocyte-like cells in the human lung after lipopolysaccharide inhalation.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2012;40(1):206-14.
2012: Wan-Seob Cho; Mark Bradley; Rodger Duffin; William MacNee; Ian L Megson; Craig A Poland; Frank Thielbeer; C Lang Tran; Ken Donaldson
Zeta potential and solubility to toxic ions as mechanisms of lung inflammation caused by metal/metal oxide nanoparticles.
Toxicological sciences : an official journal of the Society of Toxicology 2012;126(2):469-77.
2012: Wan-Seob Cho; Mark Bradley; Rodger Duffin; Albert Duschl; William MacNee; Ian L Megson; Gertie J Oostingh; Craig A Poland; Ken Donaldson
Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions in vitro and in vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs.
Nanotoxicology 2012;6(1):22-35.
2012: Sarah Robertson; Catherine A Shaw; David E Newby; Rodger Duffin; Gillian A Gray; Patrick W F Hadoke; Steven G McLean; Mark R Miller
Diesel exhaust particulate induces pulmonary and systemic inflammation in rats without impairing endothelial function ex vivo or in vivo.
Particle and fibre toxicology 2012;9():9.
2011: Nicholas L Mills; Thomas Sandstrom; Jon Beveridge; Anders Blomberg; john boere; Nicholas A Boon; Flemming R Cassee; Ken Donaldson; Rodger Duffin; Laura Flint; Paul H B Fokkens; Patrick W F Hadoke; Andrew J Lucking; Mark R Miller; David E Newby
Combustion-derived nanoparticulate induces the adverse vascular effects of diesel exhaust inhalation.
European heart journal 2011;32(21):2660-71.
2011: Michael A Gibbons; Christopher Haslett; Sarah E Howie; Alison C Mackinnon; Alexander T Phythian-Adams; Prakash Ramachandran; A John Simpson; Nico van Rooijen; Jack Gauldie; Nikhil Hirani; John P Iredale; Tariq Sethi; Kevin Dhaliwal; Rodger Duffin; Stuart J Forbes
Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis.
American journal of respiratory and critical care medicine 2011;184(5):569-81.
2011: Fiona A Murphy; Craig A Poland; Rodger Duffin; Khuloud T Al-Jamal; Hanene Ali-Boucetta; Antonio Nunes; Fiona Byrne; Adriele Prina Mello; Yuri Volkov; Shouping Li; Stephen J Mather; Alberto Bianco; Maurizio Prato; William MacNee; William A Wallace; Kostas Kostarelos; Ken Donaldson
Length-dependent retention of carbon nanotubes in the pleural space of mice initiates sustained inflammation and progressive fibrosis on the parietal pleura.
The American journal of pathology 2011;178(6):2587-600.
2011: Catherine A Shaw; Caroline M Tabor; Ken Donaldson; Rodger Duffin; Mark R Miller; David E Newby; Sarah Robertson; Patrick W F Hadoke
Diesel exhaust particulate--exposed macrophages cause marked endothelial cell activation.
American journal of respiratory cell and molecular biology 2011;44(6):840-51.
2011: Catherine McGuinnes; Rodger Duffin; Simon Brown; Nicholas L Mills; Ian L Megson; William MacNee; Shonna Johnston; Sen Lin Lu; Lang Tran; Rufia Li; Xue Wang; David E Newby; Ken Donaldson
Surface derivatization state of polystyrene latex nanoparticles determines both their potency and their mechanism of causing human platelet aggregation in vitro.
Toxicological sciences : an official journal of the Society of Toxicology 2011;119(2):359-68.
2011: Ana L Alessandri; Lirlândia Pires de Sousa; David A Dorward; Rodger Duffin; Christopher Haslett; Nik Hirani; Andrew E Leitch; Christopher D Lucas; John F Lyons; Vanessa Pinho; Tara A Sheldrake; Mauro M Teixeira; Adriano G Rossi
Induction of eosinophil apoptosis by the cyclin-dependent kinase inhibitor AT7519 promotes the resolution of eosinophil-dominant allergic inflammation.
PloS one 2011;6(9):e25683.
2011: Wan-Seob Cho; Mark Bradley; Rodger Duffin; Sarah E M Howie; William MacNee; Ian L Megson; Chris J Scotton; William A H Wallace; Ken Donaldson
Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes.
Particle and fibre toxicology 2011;8():27.
2011: Ken Donaldson; Fiona Murphy; Anja Schinwald; Rodger Duffin; Craig A Poland
Identifying the pulmonary hazard of high aspect ratio nanoparticles to enable their safety-by-design.
Nanomedicine (London, England) 2011;6(1):143-56.
2010: Wan-Seob Cho; Rodger Duffin; Craig A Poland; Sarah E M Howie; William MacNee; Mark Bradley; Ian L Megson; Ken Donaldson
Metal oxide nanoparticles induce unique inflammatory footprints in the lung: important implications for nanoparticle testing.
Environmental health perspectives 2010;118(12):1699-706.
2010: Rodger Duffin; Andrew E Leitch; Sarah Fox; Chris Haslett; Adriano G Rossi
Targeting granulocyte apoptosis: mechanisms, models, and therapies.
Immunological reviews 2010;236():28-40.
2010: Irini Bournazou; Karen J Mackenzie; Rodger Duffin; Adriano G Rossi; Christopher D Gregory
Inhibition of eosinophil migration by lactoferrin.
Immunology and cell biology 2010;88(2):220-3.
2009: Rodger Duffin; Andrew E Leitch; Tara A Sheldrake; John M Hallett; Colette Meyer; Sarah Fox; Ana L Alessandri; Morag C Martin; Hugh J Brady; Mauro M Teixeira; Ian Dransfield; Christopher Haslett; Adriano G Rossi
The CDK inhibitor, R-roscovitine, promotes eosinophil apoptosis by down-regulation of Mcl-1.
FEBS letters 2009;583(15):2540-6.
2009: Mark R Miller; Stephen J Borthwick; Catherine A Shaw; Steven G McLean; Daniel McClure; Nicholas L Mills; Rodger Duffin; Ken Donaldson; Ian L Megson; Patrick W F Hadoke; David E Newby
Direct impairment of vascular function by diesel exhaust particulate through reduced bioavailability of endothelium-derived nitric oxide induced by superoxide free radicals.
Environmental health perspectives 2009;117(4):611-6.
2009: Thomas S Wilkinson; Kevin Dhaliwal; Thomas W Hamilton; Alexander F Lipka; Lesley Farrell; Donald J Davidson; Rodger Duffin; Andrew Conway Morris; Christopher Haslett; John R W Govan; Christopher D Gregory; Jean-Michel Sallenave; A John Simpson
Trappin-2 promotes early clearance of Pseudomonas aeruginosa through CD14-dependent macrophage activation and neutrophil recruitment.
The American journal of pathology 2009;174(4):1338-46.
2009: Senlin Lu; Rodger Duffin; Craig Poland; Paul Daly; Fiona Murphy; Ellen Drost; William MacNee; Vicki Stone; Ken Donaldson
Efficacy of simple short-term in vitro assays for predicting the potential of metal oxide nanoparticles to cause pulmonary inflammation.
Environmental health perspectives 2009;117(2):241-7.
2008: Martin J D Clift; Barbara Rothen-Rutishauser; David M Brown; Rodger Duffin; Ken Donaldson; Lorna Proudfoot; Keith Guy; Vicki Stone
The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line.
Toxicology and applied pharmacology 2008;232(3):418-27.
2008: John M Hallett; Andrew E Leitch; Nicola A Riley; Rodger Duffin; Christopher Haslett; Adriano G Rossi
Novel pharmacological strategies for driving inflammatory cell apoptosis and enhancing the resolution of inflammation.
Trends in pharmacological sciences 2008;29(5):250-7.
2008: Rodger Duffin; Catherine A Shaw; Adriano G Rossi
Sildenafil reduces alcohol-induced gastric damage: just say 'NO'.
British journal of pharmacology 2008;153(4):623-4.
2007: Rodger Duffin; Nicholas L Mills; Ken Donaldson
Nanoparticles-a thoracic toxicology perspective.
Yonsei medical journal 2007;48(4):561-72.
2007: Rodger Duffin; Lang Tran; David Brown; Vicki Stone; Ken Donaldson
Proinflammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: highlighting the role of particle surface area and surface reactivity.
Inhalation toxicology 2007;19(10):849-56.
2007: Seema Singh; Tingming Shi; Rodger Duffin; Catrin Albrecht; Damien van Berlo; Doris Höhr; Bice Fubini; Gianmario Martra; Ivana Fenoglio; Paul J A Borm; Roel P F Schins
Endocytosis, oxidative stress and IL-8 expression in human lung epithelial cells upon treatment with fine and ultrafine TiO2: role of the specific surface area and of surface methylation of the particles.
Toxicology and applied pharmacology 2007;222(2):141-51.
2007: Agnes W Boots; Hui Li; Roel P F Schins; Rodger Duffin; Johan W M Heemskerk; Aalt Bast; Guido R M M Haenen
The quercetin paradox.
Toxicology and applied pharmacology 2007;222(1):89-96.
2007: Petra Haberzettl; Rodger Duffin; Ursula Krämer; Doris Höhr; Roel P F Schins; Paul J A Borm; Catrin Albrecht
Actin plays a crucial role in the phagocytosis and biological response to respirable quartz particles in macrophages.
Archives of toxicology 2007;81(7):459-70.
2007: Daniel S McQueen; Ken Donaldson; Susan M Bond; Jane D McNeilly; S Newman; Nicola J Barton; Rodger Duffin
Bilateral vagotomy or atropine pre-treatment reduces experimental diesel-soot induced lung inflammation.
Toxicology and applied pharmacology 2007;219(1):62-71.
2006: Adriano G Rossi; Deborah A Sawatzky; Annemieke Walker; Carol Ward; Tara A Sheldrake; Nicola A Riley; Alison Caldicott; Magdalena Martinez-Losa; Trevor R Walker; Rodger Duffin; Mohini Gray; Elvira Crescenzi; Morag C Martin; Hugh J M Brady; John Savill; Ian Dransfield; Christopher Haslett
Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis.
Nature medicine 2006;12(9):1056-64.
2006: Ken Donaldson; Robert Aitken; Lang Tran; Vicki Stone; Rodger Duffin; Gavin Forrest; Andrew Alexander
Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety.
Toxicological sciences : an official journal of the Society of Toxicology 2006;92(1):5-22.
2006: Tingming Shi; Rodger Duffin; Paul J A Borm; Hui Li; Christel Weishaupt; Roel P F Schins
Hydroxyl-radical-dependent DNA damage by ambient particulate matter from contrasting sampling locations.
Environmental research 2006;101(1):18-24.
2006: Stefan Geh; Raif Yücel; Rodger Duffin; Catrin Albrecht; Paul J A Borm; Lorenz Armbruster; Monika Raulf-Heimsoth; Thomas Brüning; Eik Hoffmann; Albert W Rettenmeier; Elke Dopp
Cellular uptake and cytotoxic potential of respirable bentonite particles with different quartz contents and chemical modifications in human lung fibroblasts.
Archives of toxicology 2006;80(2):98-106.
2005: Ken Donaldson; Lang Tran; Luis A Jimenez; Rodger Duffin; David E Newby; Nicholas L Mills; William MacNee; Vicki Stone
Combustion-derived nanoparticles: a review of their toxicology following inhalation exposure.
Particle and fibre toxicology 2005;2():10.
2004: Vicki Stone; R Jones; K Rollo; Rodger Duffin; Ken Donaldson; David M Brown
Effect of coal mine dust and clay extracts on the biological activity of the quartz surface.
Toxicology letters 2004;149(1-3):255-9.
2002: Roel P F Schins; Rodger Duffin; Doris Höhr; Ad M Knaapen; Tingming Shi; Christel Weishaupt; Vicki Stone; Ken Donaldson; Paul J A Borm
Surface modification of quartz inhibits toxicity, particle uptake, and oxidative DNA damage in human lung epithelial cells.
Chemical research in toxicology 2002;15(9):1166-73.
2002: Ken Donaldson; David Brown; Anna Clouter; Rodger Duffin; William MacNee; Louise Renwick; Lang Tran; Vicki Stone
The pulmonary toxicology of ultrafine particles.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 2002;15(2):213-20.
2001: Rodger Duffin; Peter S Gilmour; Roel P F Schins; Anna Clouter; Keith Guy; David M Brown; William MacNee; Paul J A Borm; Ken Donaldson; Vicki Stone
Aluminium lactate treatment of DQ12 quartz inhibits its ability to cause inflammation, chemokine expression, and nuclear factor-kappaB activation.
Toxicology and applied pharmacology 2001;176(1):10-7.
2001: Ken Donaldson; Vicki Stone; Rodger Duffin; Anna Clouter; Roel P F Schins; Paul J A Borm
The quartz hazard: effects of surface and matrix on inflammogenic activity.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2001;20 Suppl 1():109-18.
2000: Luis A Jiménez; J Thompson; D A Brown; Irfan Rahman; Frank Antonicelli; Rodger Duffin; Ellen M Drost; Ron Thomas Hay; Ken Donaldson; William MacNee
Activation of NF-kappaB by PM(10) occurs via an iron-mediated mechanism in the absence of IkappaB degradation.
Toxicology and applied pharmacology 2000;166(2):101-10.