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Heather Duffy

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Elena Dolmatova; Cinzia Ambrosi; Jennifer R Baum; Daniela Boassa; Kimberly Keith; Maria I Kontaridis; Paul L Sorgen; Gina E Sosinsky; Gaelle Spagnol; Heather S Duffy
Cardiomyocyte ATP release through pannexin 1 aids in early fibroblast activation.
Xiaojin An; Brittany L Cully; Heather S Duffy; Ping He; Yi Jin; Angela Messmer-Blust; Melissa J Philbrick; Xiaoxiao Song; Jiaping Wu; Ming Xu; Jian Li
Endothelial cells require related transcription enhancer factor-1 for cell-cell connections through the induction of gap junction proteins.
Gerard J J Boink; Penelope A Boyden; Peter R Brink; Ming Chen; Ira S Cohen; Peter Danilo; Helen E Driessen; Heather S Duffy; Wen Dun; Yelena Kryukova; David H Lau; Richard B Robinson; Tove S Rosen; Iryna N Shlapakova; Eugene A Sosunov; Nazira Ozgen; Evgeny P Anyukhovsky; Michael R Rosen
SkM1 and Cx32 improve conduction in canine myocardial infarcts yet only SkM1 is antiarrhythmic.

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All Publications

2012: Elena Dolmatova; Cinzia Ambrosi; Jennifer R Baum; Daniela Boassa; Kimberly Keith; Maria I Kontaridis; Paul L Sorgen; Gina E Sosinsky; Gaelle Spagnol; Heather S Duffy
Cardiomyocyte ATP release through pannexin 1 aids in early fibroblast activation.
American journal of physiology. Heart and circulatory physiology 2012;303(10):H1208-18.
2012: Xiaojin An; Brittany L Cully; Heather S Duffy; Ping He; Yi Jin; Angela Messmer-Blust; Melissa J Philbrick; Xiaoxiao Song; Jiaping Wu; Ming Xu; Jian Li
Endothelial cells require related transcription enhancer factor-1 for cell-cell connections through the induction of gap junction proteins.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(8):1951-9.
2012: Gerard J J Boink; Penelope A Boyden; Peter R Brink; Ming Chen; Ira S Cohen; Peter Danilo; Helen E Driessen; Heather S Duffy; Wen Dun; Yelena Kryukova; David H Lau; Richard B Robinson; Tove S Rosen; Iryna N Shlapakova; Eugene A Sosunov; Nazira Ozgen; Evgeny P Anyukhovsky; Michael R Rosen
SkM1 and Cx32 improve conduction in canine myocardial infarcts yet only SkM1 is antiarrhythmic.
Cardiovascular research 2012;94(3):450-9.
2012: Jennifer R Baum; Candido Cabo; Biao Long; Heather S Duffy
Myofibroblasts cause heterogeneous Cx43 reduction and are unlikely to be coupled to myocytes in the healing canine infarct.
American journal of physiology. Heart and circulatory physiology 2012;302(3):H790-800.
2012: David W Van Norstrand; Angeliki Asimaki; Elena Dolmatova; Heather S Duffy; Clio Rubinos; Jeffrey E Saffitz; Miduturu Srinivas; David J Tester; Michael J Ackerman
Connexin43 mutation causes heterogeneous gap junction loss and sudden infant death.
Circulation 2012;125(3):474-81.
2012: Jennifer R Baum; Elena Dolmatova; Alex Tan; Heather S Duffy
Omega 3 fatty acid inhibition of inflammatory cytokine-mediated Connexin43 regulation in the heart.
Frontiers in physiology 2012;3():272.
2011: Ali A Sovari; Kun Wang; Shadi Zandieh; Kenneth E Bernstein; Marcelo Bonini; Elena Dolmatova; Heather S Duffy; Shahriar Iravanian; Zhe Jiao; Vibhash Kumar; Hong Liu; Samuel C Dudley
Inhibition of c-Src tyrosine kinase prevents angiotensin II-mediated connexin-43 remodeling and sudden cardiac death.
Journal of the American College of Cardiology 2011;58(22):2332-9.
2011: Shahriar Iravanian; Zhe Jiao; Harvey A Lardin; Hong Liu; Ali A Sovari; Emily A Witham; Hong D Xiao; Kenneth E Bernstein; Elena Dolmatova; Heather S Duffy; Robert G Gourdie; Brett S Harris; Samuel C Dudley
Inhibition of renin-angiotensin system (RAS) reduces ventricular tachycardia risk by altering connexin43.
Journal of molecular medicine (Berlin, Germany) 2011;89(7):677-87.
2011: Ester Macia; Alexandra Z Sosinsky; Andrew L Wit; Wen Dun; Penelope A Boyden; Candido Cabo; Edward J Ciaccio; James Coromilas; Elena Dolmatova; Heather S Duffy
Characterization of gap junction remodeling in epicardial border zone of healing canine infarcts and electrophysiological effects of partial reversal by rotigaptide.
Circulation. Arrhythmia and electrophysiology 2011;4(3):344-51.
2011: Gina E Sosinsky; david spray; Roger J Thompson; Hong-Bo Zhao; Rolf Dermietzel; Heather S Duffy; Dale W Laird; Brian MacVicar; Christian C Naus; Silvia Penuela; Eliana Scemes; Daniela Boassa; Gerhard Dahl
Pannexin channels are not gap junction hemichannels.
Channels (Austin, Tex.) 2011;5(3):193-7.
2011: Bin Zhou; Leah B Honor; Huamei He; Qing Ma; Jin-Hee Oh; Catherine Butterfield; Ruei-Zeng Lin; Juan M Melero-Martin; Elena Dolmatova; Heather S Duffy; Alexander von Gise; Pingzhu Zhou; Yong Wu Hu; Gang Wang; Bing Zhang; Lianchun Wang; Jennifer L Hall; Marsha A Moses; Francis X McGowan; William T Pu
Adult mouse epicardium modulates myocardial injury by secreting paracrine factors.
The Journal of clinical investigation 2011;121(5):1894-904.
2011: Jennifer Baum; Heather S Duffy
Fibroblasts and myofibroblasts: what are we talking about?
Journal of cardiovascular pharmacology 2011;57(4):376-9.
2011: Kevin A Prestia; Eugene A Sosunov; Evgeny P Anyukhovsky; Elena Dolmatova; Caitlin W Kelly; Peter R Brink; Richard B Robinson; Michael R Rosen; Heather S Duffy
Increased Cell-Cell Coupling Increases Infarct Size and Does not Decrease Incidence of Ventricular Tachycardia in Mice.
Frontiers in physiology 2011;2():1.
2010: Wajid Hussain; Pravina M Patel; Rasheda A Chowdhury; Candido Cabo; Edward J Ciaccio; Max J Lab; Heather S Duffy; Andrew L Wit; Nicholas S Peters
The Renin-Angiotensin system mediates the effects of stretch on conduction velocity, connexin43 expression, and redistribution in intact ventricle.
Journal of cardiovascular electrophysiology 2010;21(11):1276-83.
2009: Heather S Duffy
The ever-shrinking world of cardiac ion channel remodeling: the role of microRNAs in heart disease.
Heart rhythm : the official journal of the Heart Rhythm Society 2009;6(12):1810-1.
2009: David H Lau; Chris Clausen; Eugene A Sosunov; Iryna N Shlapakova; Evgeny P Anyukhovsky; Peter Danilo; Tove S Rosen; Caitlin Kelly; Heather S Duffy; Matthias Szabolcs; Ming Chen; Richard B Robinson; Jia Lu; Sinhu Kumari; Ira S Cohen; Michael R Rosen
Epicardial border zone overexpression of skeletal muscle sodium channel SkM1 normalizes activation, preserves conduction, and suppresses ventricular arrhythmia: an in silico, in vivo, in vitro study.
Circulation 2009;119(1):19-27.
2008: Heather S Duffy
Cardiac connections--the antiarrhythmic solution?
The New England journal of medicine 2008;358(13):1397-8.
2008: Heather S Duffy; Andrew L Wit
Is there a role for remodeled connexins in AF? No simple answers.
Journal of molecular and cellular cardiology 2008;44(1):4-13.
2008: Andrew L Wit; Heather S Duffy
Drug development for treatment of cardiac arrhythmias: targeting the gap junctions.
American journal of physiology. Heart and circulatory physiology 2008;294(1):H16-8.
2007: Nazira Ozgen; Wen Dun; Eugene A Sosunov; Evgeny P Anyukhovsky; Masanori Hirose; Heather S Duffy; Penelope A Boyden; Michael R Rosen
Early electrical remodeling in rabbit pulmonary vein results from trafficking of intracellular SK2 channels to membrane sites.
Cardiovascular research 2007;75(4):758-69.
2007: Heather S Duffy; Ionela Iacobas; Kylie Hotchkiss; Bethany J Hirst-Jensen; Alejandra Bosco; Nadine Dandachi; Rolf Dermietzel; Paul L Sorgen; david spray
The gap junction protein connexin32 interacts with the Src homology 3/hook domain of discs large homolog 1.
The Journal of biological chemistry 2007;282(13):9789-96.
2006: Candido Cabo; Jianan Yao; Penelope A Boyden; Shan Chen; Wajid Hussain; Heather S Duffy; Edward J Ciaccio; Nicholas S Peters; Andrew L Wit
Heterogeneous gap junction remodeling in reentrant circuits in the epicardial border zone of the healing canine infarct.
Cardiovascular research 2006;72(2):241-9.
2006: Heather S Duffy; Alfredo G Fort; david spray
Cardiac connexins: genes to nexus.
Advances in cardiology 2006;42():1-17.
2004: Paul L Sorgen; Heather S Duffy; Prangya Sahoo; Wanda Coombs; Mario Delmar; david spray
Structural changes in the carboxyl terminus of the gap junction protein connexin43 indicates signaling between binding domains for c-Src and zonula occludens-1.
The Journal of biological chemistry 2004;279(52):54695-701.
2004: Akiko Seki; Heather S Duffy; Wanda Coombs; david spray; Steven Taffet; Mario Delmar
Modifications in the biophysical properties of connexin43 channels by a peptide of the cytoplasmic loop region.
Circulation research 2004;95(4):e22-8.
2004: Paul L Sorgen; Heather S Duffy; david spray; Mario Delmar
pH-dependent dimerization of the carboxyl terminal domain of Cx43.
Biophysical journal 2004;87(1):574-81.
2004: Mario Delmar; Wanda Coombs; Paul L Sorgen; Heather S Duffy; Steven Taffet
Structural bases for the chemical regulation of Connexin43 channels.
Cardiovascular research 2004;62(2):268-75.
2004: Heather S Duffy; Anthony W Ashton; Phyllis O'Donnell; Wanda Coombs; Steven Taffet; Mario Delmar; david spray
Regulation of connexin43 protein complexes by intracellular acidification.
Circulation research 2004;94(2):215-22.
2003: Heather S Duffy; Phyllis O'Donnell; Wanda Coombs; Steven Taffet; Mario Delmar; david spray
Kinetics of protein-protein interactions of connexins: use of enzyme linked sorbent assays.
Cell communication & adhesion 2003;10(4-6):207-10.
2002: Heather S Duffy; Paul L Sorgen; Mark E Girvin; Phyllis O'Donnell; Wanda Coombs; Steven Taffet; Mario Delmar; david spray
pH-dependent intramolecular binding and structure involving Cx43 cytoplasmic domains.
The Journal of biological chemistry 2002;277(39):36706-14.
2002: Paul L Sorgen; Heather S Duffy; Sean M Cahill; Wanda Coombs; david spray; Mario Delmar; Mark E Girvin
Sequence-specific resonance assignment of the carboxyl terminal domain of Connexin43.
Journal of biomolecular NMR 2002;23(3):245-6.
2002: Heather S Duffy; Mario Delmar; david spray
Formation of the gap junction nexus: binding partners for connexins.
Journal of physiology, Paris 2002;96(3-4):243-9.
2001: Heather S Duffy; Mario Delmar; Wanda Coombs; S M Tafftet; E L Hertzberg; david spray
Functional demonstration of connexin-protein binding using surface plasmon resonance.
Cell communication & adhesion 2001;8(4-6):225-9.
1999: david spray; Heather S Duffy; Eliana Scemes
Gap junctions in glia. Types, roles, and plasticity.
Advances in experimental medicine and biology 1999;468():339-59.