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Ulrich Dührsen

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B-Cell Chronic Lymphocytic Leukemia

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Lewin Eisele; Raimund Erbel; Karl-Heinz Jöckel; Susanne Moebus; Beate Bokhof; Martina Broecker-Preuss; Ulrich Dührsen; Jan Dürig
Prevalence and incidence of anemia in the German Heinz Nixdorf Recall Study.
Cyrus Khandanpour; Joseph Krongold; Riyan Chen; Ulrich Dührsen; Marie-Claude Gaudreau; Bertie Göttgens; H Leighton Grimes; Shane R Horman; William E Paul; James D Phelan; Judith Schütte; Lothar Vassen; Jinfang Zhu; Tarik Möröy
Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia.
Martin Neumann; Cornelia Schlee; Stefan Schwartz; Eckhard Thiel; Nasrin Farhadi Sartangi; Isabelle Bartram; Olga Blau; Christian Brandts; Thomas Burmeister; Ebru Coskun; Hartmut Döhner; Ulrich Dührsen; Gerhard Ehninger; Lars Fransecky; Nicola Gökbuget; Martin Griesshammer; Rainer Haas; Sandra Heesch; Dieter Hoelzer; Wolf-Karsten Hofmann; Liliana H Mochmann; Claudia D Baldus
FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors.

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2013: Lewin Eisele; Raimund Erbel; Karl-Heinz Jöckel; Susanne Moebus; Beate Bokhof; Martina Broecker-Preuss; Ulrich Dührsen; Jan Dürig
Prevalence and incidence of anemia in the German Heinz Nixdorf Recall Study.
Annals of hematology 2013;92(6):731-7.
2013: Cyrus Khandanpour; Joseph Krongold; Riyan Chen; Ulrich Dührsen; Marie-Claude Gaudreau; Bertie Göttgens; H Leighton Grimes; Shane R Horman; William E Paul; James D Phelan; Judith Schütte; Lothar Vassen; Jinfang Zhu; Tarik Möröy
Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia.
Cancer cell 2013;23(2):200-14.
2013: Martin Neumann; Cornelia Schlee; Stefan Schwartz; Eckhard Thiel; Nasrin Farhadi Sartangi; Isabelle Bartram; Olga Blau; Christian Brandts; Thomas Burmeister; Ebru Coskun; Hartmut Döhner; Ulrich Dührsen; Gerhard Ehninger; Lars Fransecky; Nicola Gökbuget; Martin Griesshammer; Rainer Haas; Sandra Heesch; Dieter Hoelzer; Wolf-Karsten Hofmann; Liliana H Mochmann; Claudia D Baldus
FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors.
PloS one 2013;8(1):e53190.
2012: Christian Gisselbrecht; Andre Bosly; Josette Brière; Ulrich Dührsen; Hans Hagberg; Nicolas Ketterer; David C Linch; Ray Lowenthal; David D Ma; Noel J Milpied; Craig H Moskowitz; Nicolas Mounier; John Radford; Gilles SALLES; Norbert Schmitz; Ofer Shpilberg; Devinder Singh Gill; Marek Trneny; Andreas Viardot; Bertram Glaß
Rituximab maintenance therapy after autologous stem-cell transplantation in patients with relapsed CD20(+) diffuse large B-cell lymphoma: final analysis of the collaborative trial in relapsed aggressive lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(36):4462-9.
2012: Cyrus Khandanpour; Joseph Krongold; Bob Löwenberg; Sara E Meyer; Chandrashekhar V Patel; Justine K Peeters; Judith Schütte; Bert A van der Reijden; Lothar Vassen; Frederique Bouwman; Fernando J Calero-Nieto; Riyan Chen; Evangelia Diamanti; Ulrich Dührsen; Marie-Claude Gaudreau; Bertie Göttgens; H Leighton Grimes; Rebecca Hannah; Joop H Jansen; Tarik Möröy
The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice.
Blood 2012;120(19):4006-17.
2012: A Sprüssel; T Thor; J Vandesompele; S Weber; R Buettner; L Diehl; Ulrich Dührsen; A Eggert; K Händschke; Lukas Heukamp; Holger Jastrow; K König; Pieter Mestdagh; M Necke; K W Pajtler; A Schramm; R Schüle; Johannes H Schulte; F Speleman; Joachim R Göthert
Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation.
Leukemia 2012;26(9):2039-51.
2012: Heike Pfeifer; M Schmalzing; A Schmidt; Hubert Serve; Matthias Stelljes; Barbara Wassmann; Lydia Wunderle; S Wystub; Anja Binckebanck; Patrick Brück; Ulrich Dührsen; Aristoteles Giagounidis; Dieter Hoelzer; Thoralf Lange; J Maier; Oliver G Ottmann
Prevalence and dynamics of bcr-abl kinase domain mutations during imatinib treatment differ in patients with newly diagnosed and recurrent bcr-abl positive acute lymphoblastic leukemia.
Leukemia 2012;26(7):1475-81.
2012: Ludger Sellmann; Dörte Siemer; Jens Stanelle; Holger Nückel; René Scholtysik; Alexander Carpinteiro; Ulrich Dührsen; Jan Dürig; Ludger Klein-Hipass; Dieter Kube; Ralf Küppers
p53 protein expression in chronic lymphocytic leukemia.
Leukemia & lymphoma 2012;53(7):1282-8.
2012: Peter Dreger; Ulrich Dührsen; Anna-Maria Fink; Hildegard Greinix; Michael Hallek; Manfred Hensel; Wolfgang Knauf; Michael Kneba; Fabienne McClanahan; Michael Pfreundschuh; Matthias Ritgen; Johannes Schetelig; Norbert Schmitz; Michael Stadler; Stephan Stilgenbauer; Dirk Winkler; Günter Brittinger; Andreas Bühler; Raymonde Busch; Hartmut Döhner
Early autologous stem cell transplantation for chronic lymphocytic leukemia: long-term follow-up of the German CLL Study Group CLL3 trial.
Blood 2012;119(21):4851-9.
2012: Holger Nückel; Marc Wichert; Roland Assert; Hartmut Döhner; Ulrich Dührsen; Stefan Herget-Rosenthal; Christian Langer; Peter Liebisch
Prognostic significance of serum cystatin C in multiple myeloma.
International journal of hematology 2012;95(5):545-50.
2012: Ruth Pettengell; Francesca G Rossi; Matthias Schwenkglenks; Antonio Salar Silvestre; Zsolt Szabo; Hans E Johnsen; Kate Bendall; Ulrich Dührsen; Hans E Johnson; Pieternella J Lugtenburg; Ulrich Jaeger
Impact of febrile neutropenia on R-CHOP chemotherapy delivery and hospitalizations among patients with diffuse large B-cell lymphoma.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2012;20(3):647-52.
2012: Lewin Eisele; Raimund Erbel; Andreas Hüttmann; Karl-Heinz Jöckel; Klaus Mann; Susanne Moebus; Roland Assert; Beate Bokhof; Ulrich Dührsen; Jan Dürig
Prevalence and progression of monoclonal gammopathy of undetermined significance and light-chain MGUS in Germany.
Annals of hematology 2012;91(2):243-8.
2012: Kai Neben; Norma Peter; Michael Pfreundschuh; Marc S Raab; Hans Salwender; Christof Scheid; Ingo G H Schmidt-Wolf; Pieter Sonneveld; Christian Teschendorf; Helgi van de Velde; Bronno van der Holt; Katja Weisel; Mathias Haenel; Thomas Hielscher; Anthony D Ho; Dirk Hose; Anna Jauch; Walter Lindemann; Henk M Lokhorst; Hans Martin; Uta Bertsch; Igor W Blau; Hans G Derigs; Ulrich Dührsen; Hartmut Goldschmidt
Administration of bortezomib before and after autologous stem cell transplantation improves outcome in multiple myeloma patients with deletion 17p.
Blood 2012;119(4):940-8.
2012: Utz Krug; Wolfgang E Berdel; Christian Brandts; Thomas Büchner; Gesine Bug; Ulrich Dührsen; Gerhard Ehninger; Joachim Gerss; Anja Koschmieder; Steffen Koschmieder; Richard Noppeney; Christoph Röllig; Markus Schaich; Daniela Schwammbach; Hubert Serve; Björn Steffen; Matthias Stelljes; Christian Thiede; Nicola Tidow; Carsten Müller-Tidow
Feasibility of azacitidine added to standard chemotherapy in older patients with acute myeloid leukemia--a randomised SAL pilot study.
PloS one 2012;7(12):e52695.
2012: Lothar Vassen; Hui Zeng; Ulrich Dührsen; Christian Kosan; Tarik Möröy
Growth factor independence 1 (Gfi1) regulates cell-fate decision of a bipotential granulocytic-monocytic precursor defined by expression of Gfi1 and CD48.
American journal of blood research 2012;2(4):228-42.
2012: Maher Hanoun; Andreas Hüttmann; Ludger Klein-Hitpass; René Scholtysik; Masako Suzuki; Semra Aydin; Ulrich Dührsen; Lewin Eisele; John M Greally; Jan Dürig
Epigenetic silencing of the circadian clock gene CRY1 is associated with an indolent clinical course in chronic lymphocytic leukemia.
PloS one 2012;7(3):e34347.
2011: Alexander Röth; Ulrich Dührsen
Treatment of paroxysmal nocturnal hemoglobinuria in the era of eculizumab.
European journal of haematology 2011;87(6):473-9.
2011: Maher Hanoun; Alexander Röth; Ulrich Dührsen; Franz-Eduard Brock
Acral ischemia as a presenting manifestation of essential thrombocythemia.
International journal of hematology 2011;94(3):219-20.
2011: A Wree; Ali Canbay; A Dechêne; Ulrich Dührsen; Guido Gerken; F Lammert; Hannes Müller-Beissenhirtz; Holger Nückel
Excessive bilirubin elevation in a patient with hereditary spherocytosis and intrahepatic cholestasis.
Zeitschrift für Gastroenterologie 2011;49(8):977-80.
2011: Semra Aydin; Alexander Carpinteiro; Ulrich Dührsen; Peter Ebeling; Lewin Eisele; Joachim R Göthert; Florian Grabellus; Maher Hanoun; Michael Möllmann; Thomas Moritz; Holger Nückel; Ali Sak; Jan Dürig
Investigating the role of CD38 and functionally related molecular risk factors in the CLL NOD/SCID xenograft model.
European journal of haematology 2011;87(1):10-9.
2011: Alexander Röth; Sandra Christoph; Christina Hock; Anna Konik; Ulrich Dührsen
Chronic treatment of paroxysmal nocturnal hemoglobinuria patients with eculizumab: safety, efficacy, and unexpected laboratory phenomena.
International journal of hematology 2011;93(6):704-14.
2011: André Tichelli; Hubert Schrezenmeier; Gérard Socié; Judith Marsh; Andrea Bacigalupo; Ulrich Dührsen; Anke Franzke; Michael Hallek; Eckhard Thiel; Martin Wilhelm; Britta Höchsmann; Alain Barrois; Kim Champion; Jakob R Passweg
A randomized controlled study in patients with newly diagnosed severe aplastic anemia receiving antithymocyte globulin (ATG), cyclosporine, with or without G-CSF: a study of the SAA Working Party of the European Group for Blood and Marrow Transplantation.
Blood 2011;117(17):4434-41.
2011: Jan Dürig; Ulrich Dührsen; Ludger Klein-Hitpass; J Worm; J B Rode Hansen; H Ørum; M Wissenbach
The novel antisense Bcl-2 inhibitor SPC2996 causes rapid leukemic cell clearance and immune activation in chronic lymphocytic leukemia.
Leukemia 2011;25(4):638-47.
2011: Ulrich Dührsen; Christian P Kratz; Christian Flotho; Thomas C Lauenstein; Martin Bommer; Erika König; Günter Brittinger; Hermann Heimpel
Long-term outcome of hemizygous and heterozygous carriers of a germline GATA1 (G208R) mutation.
Annals of hematology 2011;90(3):301-6.
2011: Cyrus Khandanpour; Christian Kosan; Ulrich Dührsen; Marie-Claude Gaudreau; Josée Hébert; Hui Zeng; Tarik Möröy
Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease.
Stem cells (Dayton, Ohio) 2011;29(2):376-85.
2011: Ludger Sellmann; Dirk de Beer; Marius Bartels; Bertram Opalka; Holger Nückel; Ulrich Dührsen; Jan Dürig; Marc Seifert; Dörte Siemer; Ralf Küppers; Gabriela M Baerlocher; Alexander Röth
Telomeres and prognosis in patients with chronic lymphocytic leukaemia.
International journal of hematology 2011;93(1):74-82.
2010: Ludger Sellmann; Rene Scholtysik; Markus Kreuz; Sandra Cyrull; Enrico Tiacci; Jens Stanelle; Alexander Carpinteiro; Holger Nückel; Tanja Boes; Stefan Gesk; Reiner Siebert; Ludger Klein-Hitpass; Ulrich Dührsen; Jan Dürig; Ralf Küppers
Gene dosage effects in chronic lymphocytic leukemia.
Cancer genetics and cytogenetics 2010;203(2):149-60.
2010: Ulrich Dührsen; Andreas Hüttmann; Jan Dürig
Prognostic significance of molecular remission in follicular lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(30):e613; author reply e614.
2010: Bob Löwenberg; Gareth Morgan; Gert Ossenkoppele; Alan K Burnett; Pierre Zachée; Ulrich Dührsen; Daan Dierickx; Carsten Müller-Tidow; Pieter Sonneveld; Utz Krug; Elisabeth Bone; Nicolas Flores; Alison F Richardson; Leon Hooftman; Chris Jenkins; Sonja Zweegman; Faith Davies
Phase I/II clinical study of Tosedostat, an inhibitor of aminopeptidases, in patients with acute myeloid leukemia and myelodysplasia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(28):4333-8.
2010: Andreas Hüttmann; Stefan Müller; Karl-Heinz Jöckel; Ulrich Dührsen
Pitfalls of interim positron emission tomography scanning in diffuse large B-cell lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(27):e488-9; author reply e490-1.
2010: Marius Bartels; Dirk Theergarten; Klaus Alfred Metz; Ulrich Dührsen
[56-year-old female patient with jaundice and paraparesis].
Deutsche medizinische Wochenschrift (1946) 2010;135(38):1861-2.
2010: Hagen S Bachmann; Jürgen Novotny; Stephan Urs Sixt; Peter Liebisch; Ulrich H Frey; Ulrich Dührsen; Winfried Siffert; Holger Nückel
The G-Allele of the PSMA6-8C>G polymorphism is associated with poor outcome in multiple myeloma independently of circulating proteasome serum levels.
European journal of haematology 2010;85(2):108-13.
2010: Maher Hanoun; Klaus Jürgen Schmitz; Ulrich Dührsen; Alexander Röth
Amyloid tumour.
British journal of haematology 2010;150(4):387.
2010: Anna Konik; Ulrich Dührsen; Alexander Röth
Nodular lesions of the scalp and a mediastinal mass in T cell acute lymphoblastic leukemia.
International journal of hematology 2010;92(1):3-4.
2010: P Johansson; L Eisele; Ludger Klein-Hitpass; Ludger Sellmann; Ulrich Dührsen; Jan Dürig; Holger Nückel
Percentage of smudge cells determined on routine blood smears is a novel prognostic factor in chronic lymphocytic leukemia.
Leukemia research 2010;34(7):892-8.
2010: Holger Nückel; M Switala; Ludger Sellmann; P A Horn; Jan Dürig; Ulrich Dührsen; Ralf Küppers; Hans Grosse-Wilde; Vera Rebmann
The prognostic significance of soluble NKG2D ligands in B-cell chronic lymphocytic leukemia.
Leukemia 2010;24(6):1152-9.
2010: Cyrus Khandanpour; Christian Thiede; Peter J M Valk; Ehssan Sharif-Askari; Holger Nückel; Dietmar Lohmann; Bernhard Horsthemke; Winfried Siffert; Andreas Neubauer; Karl-Heinz Grzeschik; Clara D Bloomfield; Guido Marcucci; Kati Maharry; Marilyn L Slovak; Bert A van der Reijden; Joop H Jansen; Hans K Schackert; Khashayar Afshar; Susanne Schnittger; Justine K Peeters; Frank Kroschinsky; Gerhard Ehninger; Bob Lowenberg; Ulrich Dührsen; Tarik Möröy
A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia.
Blood 2010;115(12):2462-72.
2010: Alexander Röth; Sven Peine; Ulrich Dührsen
Paroxysmal nocturnal hemoglobinuria turning Coombs-positive.
International journal of hematology 2010;91(2):159-60.
2010: Sandra Christoph; Andreas Hüttmann; Ulrich Dührsen; Alexander Röth
Porphyria cutanea tarda.
British journal of haematology 2010;148(4):493.
2010: Lewin Eisele; Florian Günther; Peter Ebeling; Jens Nabring; Ulrich Dührsen; Jan Dürig
Outpatient management of acute myeloid leukemia after intensive consolidation chemotherapy is feasible and reduces hospital treatment costs.
Onkologie 2010;33(12):658-64.
2010: Alexander Röth; Ulrich Dührsen
Cold agglutinin disease.
European journal of haematology 2010;84(1):91.
2009: Holger Nückel; Crista Collins; Ulrich H Frey; Ludger Sellmann; Jan Dürig; Winfried Siffert; Ulrich Dührsen
FCRL2 mRNA expression is inversely associated with clinical progression in chronic lymphocytic leukemia.
European journal of haematology 2009;83(6):541-9.
2009: Thorsten Zenz; Axel Benner; Ulrich Dührsen; Jan Dürig; Hartmut Döhner; Winfried Siffert; Stephan Stilgenbauer; Holger Nückel
BCL2-938C>A polymorphism and disease progression in chronic lymphocytic leukemia.
Leukemia & lymphoma 2009;50(11):1837-42.
2009: Ulrich Dührsen; Andreas Hüttmann; Karl-Heinz Jöckel; Stefan Müller
Positron emission tomography guided therapy of aggressive non-Hodgkin lymphomas--the PETAL trial.
Leukemia & lymphoma 2009;50(11):1757-60.
2009: Lewin Eisele; Robert Prinz; Ludger Klein-Hitpass; Holger Nückel; Kerstin Lowinski; Jürgen Thomale; Lars C Moeller; Ulrich Dührsen; Jan Dürig
Combined PER2 and CRY1 expression predicts outcome in chronic lymphocytic leukemia.
European journal of haematology 2009;83(4):320-7.
2009: Hermann Heimpel; Ulrich Dührsen; P Hofbauer; V Rigamonti-Wermlinger; Ernst D Kreuser; Klaus Schwarz; Max Solenthaler; S Pauls
Bulky extramedullary hematopoiesis is not a rare complication of congenital dyserythropoietic anemia.
Annals of hematology 2009;88(10):937-41.
2009: Stephan Stilgenbauer; Thorsten Zenz; Dirk Winkler; Andreas Bühler; Richard F Schlenk; Silja Groner; Raymonde Busch; Manfred Hensel; Ulrich Dührsen; Jürgen Finke; Peter Dreger; Ulrich Jäger; Eva Lengfelder; Karin Hohloch; Ulrike Söling; Rudolf Schlag; Michael Kneba; Michael Hallek; Hartmut Döhner
Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(24):3994-4001.
2009: Stefanie Bug; Jan Dürig; Florian Oyen; Ludger Klein-Hitpass; Jose I Martin-Subero; Lana Harder; Baudis Michael; Norbert Arnold; Uwe Kordes; Ulrich Dührsen; Reinhard Schneppenheim; Reiner Siebert
Recurrent loss, but lack of mutations, of the SMARCB1 tumor suppressor gene in T-cell prolymphocytic leukemia with TCL1A-TCRAD juxtaposition.
Cancer genetics and cytogenetics 2009;192(1):44-7.
2009: Holger Nückel; Magdalena Switala; Crista Collins; Ludger Sellmann; Hans Grosse-Wilde; Ulrich Dührsen; Vera Rebmann
High CD49d protein and mRNA expression predicts poor outcome in chronic lymphocytic leukemia.
Clinical immunology (Orlando, Fla.) 2009;131(3):472-80.
2009: Lewin Eisele; Tareq Haddad; Ludger Sellmann; Ulrich Dührsen; Jan Dürig
Expression levels of CD38 on leukemic B cells but not on non-leukemic T cells are comparably stable over time and predict the course of disease in patients with chronic lymphocytic leukemia.
Leukemia research 2009;33(6):775-8.
2009: Lothar Vassen; Cyrus Khandanpour; Peter Ebeling; Bert A van der Reijden; Joop H Jansen; Stefan Mahlmann; Ulrich Dührsen; Tarik Möröy
Growth factor independent 1b (Gfi1b) and a new splice variant of Gfi1b are highly expressed in patients with acute and chronic leukemia.
International journal of hematology 2009;89(4):422-30.
2009: Alexander Röth; Andreas Hüttmann; Russell P Rother; Ulrich Dührsen; Thomas Philipp
Long-term efficacy of the complement inhibitor eculizumab in cold agglutinin disease.
Blood 2009;113(16):3885-6.
2009: Alexander Röth; Ulrich Dührsen; H Schrezenmeier; J Schubert
[Paroxysmal nocturnal hemoglobinuria (PNH). Pathogenesis, diagnosis and treatment].
Deutsche medizinische Wochenschrift (1946) 2009;134(9):404-9.
2009: Holger Nückel; Ulrich H Frey; Ludger Sellmann; Crista Collins; Ulrich Dührsen; Winfried Siffert
The IKZF3 (Aiolos) transcription factor is highly upregulated and inversely correlated with clinical progression in chronic lymphocytic leukaemia.
British journal of haematology 2009;144(2):268-70.
2008: Alexander Röth; Dirk de Beer; Holger Nückel; Ludger Sellmann; Ulrich Dührsen; Jan Dürig; Gabriela M Baerlocher
Significantly shorter telomeres in T-cells of patients with ZAP-70+/CD38+ chronic lymphocytic leukaemia.
British journal of haematology 2008;143(3):383-6.
2008: Christina A Ortmann; Lewin Eisele; Holger Nückel; Ludger Klein-Hitpass; Anja Führer; Ulrich Dührsen; Michael Zeschnigk
Aberrant hypomethylation of the cancer-testis antigen PRAME correlates with PRAME expression in acute myeloid leukemia.
Annals of hematology 2008;87(10):809-18.
2008: Eva Hoster; Martin Dreyling; Wolfram Klapper; Christian Gisselbrecht; Achiel Van Hoof; Hanneke C Kluin-Nelemans; Michael Pfreundschuh; Marcel Reiser; Bernd Metzner; Hermann Einsele; Norma Peter; Wolfram Jung; Bernhard Wörmann; Wolf-Dieter Ludwig; Ulrich Dührsen; Hartmut Eimermacher; Hannes Wandt; Joerg Hasford; Wolfgang Hiddemann; Michael Unterhalt
A new prognostic index (MIPI) for patients with advanced-stage mantle cell lymphoma.
Blood 2008;111(2):558-65.
2007: Alexander Röth; Jan Dürig; H Himmelreich; S Bug; R Siebert; Ulrich Dührsen; Peter M Lansdorp; Gabriela M Baerlocher
Short telomeres and high telomerase activity in T-cell prolymphocytic leukemia.
Leukemia 2007;21(12):2456-62.
2007: Peter Hillmen; Petra Muus; Ulrich Dührsen; Antonio M Risitano; Jörg Schubert; Lucio Luzzatto; Hubert Schrezenmeier; Jeff Szer; Robert A Brodsky; Anita Hill; Gérard Socié; Monica Bessler; Scott A Rollins; Leonard Bell; Russell P Rother; Neal S Young
Effect of the complement inhibitor eculizumab on thromboembolism in patients with paroxysmal nocturnal hemoglobinuria.
Blood 2007;110(12):4123-8.
2007: Vera Rebmann; Holger Nückel; Ulrich Dührsen; Hans Grosse-Wilde
HLA-G in B-chronic lymphocytic leukaemia: clinical relevance and functional implications.
Seminars in cancer biology 2007;17(6):430-5.
2007: Joachim R Göthert; Rachael L Brake; Monique F M A Smeets; Ulrich Dührsen; C Glenn Begley; David J Izon
NOTCH1 pathway activation is an early hallmark of SCL T leukemogenesis.
Blood 2007;110(10):3753-62.
2007: C R Bollinger; Dirk Theegarten; Ulrich Dührsen; K A Metz
[Fever and nonspecific pulmonary lesions--a rare differential diagnosis].
Deutsche medizinische Wochenschrift (1946) 2007;132(48):2563-6.
2007: Jan Dürig; S Bug; Ludger Klein-Hitpass; Tanja Boes; T Jöns; Jose I Martin-Subero; Lana Harder; Baudis Michael; Ulrich Dührsen; R Siebert
Combined single nucleotide polymorphism-based genomic mapping and global gene expression profiling identifies novel chromosomal imbalances, mechanisms and candidate genes important in the pathogenesis of T-cell prolymphocytic leukemia with inv(14)(q11q32).
Leukemia 2007;21(10):2153-63.
2007: Jan Dürig; Peter Ebeling; Florian Grabellus; Ursula R Sorg; Michael Möllmann; Philipp Schütt; Joachim Göthert; Ludger Sellmann; Siegfried Seeber; Michael Flasshove; Ulrich Dührsen; Thomas Moritz
A novel nonobese diabetic/severe combined immunodeficient xenograft model for chronic lymphocytic leukemia reflects important clinical characteristics of the disease.
Cancer research 2007;67(18):8653-61.
2007: Ludger Sellmann; Stefan Gesk; Christoph Walter; Matthias Ritgen; Lana Harder; José I Martín-Subero; Roland Schroers; Dörte Siemer; Holger Nückel; Martin J S Dyer; Ulrich Dührsen; Reiner Siebert; Jan Dürig; Ralf Küppers
Trisomy 19 is associated with trisomy 12 and mutated IGHV genes in B-chronic lymphocytic leukaemia.
British journal of haematology 2007;138(2):217-20.
2007: Oliver G Ottmann; Barbara Wassmann; Heike Pfeifer; Aristoteles Giagounidis; Matthias Stelljes; Ulrich Dührsen; Marc Schmalzing; Lydia Wunderle; Anja Binckebanck; Dieter Hoelzer
Imatinib compared with chemotherapy as front-line treatment of elderly patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL).
Cancer 2007;109(10):2068-76.
2007: Semra Aydin; Ulrich Dührsen; Holger Nückel
Rituximab plus ASHAP for the treatment of patients with relapsed or refractory aggressive non-Hodgkin's lymphoma: a single-centre study of 20 patients.
Annals of hematology 2007;86(4):271-6.
2007: Roland Schroers; Ulrich Dührsen
[Idiopathic thrombocytopenic purpura].
Deutsche medizinische Wochenschrift (1946) 2007;132(8):383-90; quiz 391-4.
2007: Alexander Röth; L Schneider; H Himmelreich; Gabriela M Baerlocher; Ulrich Dührsen
Impact of culture conditions on the proliferative lifespan of human T cells in vitro.
Cytotherapy 2007;9(1):91-8.
2007: Holger Nückel; Ulrich H Frey; Maja Bau; Ludger Sellmann; Jens Stanelle; Jan Dürig; Karl-Heinz Jöckel; Ulrich Dührsen; Winfried Siffert
Association of a novel regulatory polymorphism (-938C>A) in the BCL2 gene promoter with disease progression and survival in chronic lymphocytic leukemia.
Blood 2007;109(1):290-7.
2006: Kathrin Riemann; Lucie Becker; Henrike Struwe; Holger Nückel; Ulrich Dührsen; Hakan Alakus; Günther Winde; Markus Neuhäuser; Herbert Rübben; Klaus J Schmitz; Jeremias Wohlschlaeger; Kurt W Schmid; Winfried Siffert
No association of the NFKB1 insertion/deletion promoter polymorphism with survival in colorectal and renal cell carcinoma as well as disease progression in B-cell chronic lymphocytic leukemia.
Pharmacogenetics and genomics 2006;16(11):783-8.
2006: Ulrich H Frey; Holger Nückel; Ludger Sellmann; Dörte Siemer; Ralf Küppers; Jan Dürig; Ulrich Dührsen; Winfried Siffert
The GNAS1 T393C polymorphism is associated with disease progression and survival in chronic lymphocytic leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(19):5686-92.
2006: Andreas Hüttmann; Ludger Klein-Hitpass; Jürgen Thomale; R Deenen; A Carpinteiro; Holger Nückel; Peter Ebeling; Anja Führer; J Edelmann; Ludger Sellmann; Ulrich Dührsen; Jan Dürig
Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression status.
Leukemia 2006;20(10):1774-82.
2006: Andreas Hüttmann; Achim Gutersohn; Richard Noppeney; Till Neumann; Raimund Erbel; Ulrich Dührsen
Rapid succession of peripheral blood progenitor cell mobilization cycles in patients with chronic heart failure: effects on the hematopoietic system.
Transfusion 2006;46(8):1424-31.
2006: Georg Feldmann; Hans Dieter Nischalke; Jacob Nattermann; Brigitte Banas; Thomas Berg; Christian Teschendorf; Wolff Schmiegel; Ulrich Dührsen; Juliane Halangk; Agathe Iwan; Tilman Sauerbruch; Wolfgang H Caselmann; Ulrich Spengler
Induction of interleukin-6 by hepatitis C virus core protein in hepatitis C-associated mixed cryoglobulinemia and B-cell non-Hodgkin's lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(15):4491-8.
2006: Andreas Hüttmann; Ulrich Dührsen; Katja Heydarian; Ludger Klein-Hitpass; Tanja Boes; Andrew W Boyd; Chung-Leung Li
Gene expression profiles in murine hematopoietic stem cells revisited: analysis of cDNA libraries reveals high levels of translational and metabolic activities.
Stem cells (Dayton, Ohio) 2006;24(7):1719-27.
2006: Holger Nückel; Andreas Hüttmann; Ludger Klein-Hitpass; Roland Schroers; Anja Führer; Ludger Sellmann; Ulrich Dührsen; Jan Dürig
Lipoprotein lipase expression is a novel prognostic factor in B-cell chronic lymphocytic leukemia.
Leukemia & lymphoma 2006;47(6):1053-61.
2006: Daniel Patschan; Oliver Witzke; Ulrich Dührsen; Raimund Erbel; Thomas Philipp; Stefan Herget-Rosenthal
Acute myocardial infarction in thrombotic microangiopathies--clinical characteristics, risk factors and outcome.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(6):1549-54.
2006: Jürgen R Novotny; Holger Nückel; Ulrich Dührsen
Correlation between expression of CD56/NCAM and severe leukostasis in hyperleukocytic acute myelomonocytic leukaemia.
European journal of haematology 2006;76(4):299-308.
2006: Holger Nückel; Ulrich H Frey; Ludger Sellmann; Maja Bau; Jan Dürig; Ulrich Dührsen; Winfried Siffert
Bax gene G(-248)A promoter polymorphism and chronic lymphocytic leukemia: lack of association with incidence, disease stage and progression-free survival.
Leukemia 2006;20(4):724.
2006: Katharina Fiolka; Ronna Hertzano; Lothar Vassen; Hui Zeng; Orit Hermesh; Karen B Avraham; Ulrich Dührsen; Tarik Möröy
Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development.
EMBO reports 2006;7(3):326-33.
2006: Holger Nückel; Jürgen R Novotny; Richard Noppeney; Irini Savidou; Ulrich Dührsen
Detection of malignant haematopoietic cells in the cerebrospinal fluid by conventional cytology and flow cytometry.
Clinical and laboratory haematology 2006;28(1):22-9.
2006: Andreas Hüttmann; Ulrich Dührsen; Jörg Stypmann; Richard Noppeney; Holger Nückel; Till Neumann; Achim Gutersohn; Sigrid Nikol; Raimund Erbel
Granulocyte colony-stimulating factor-induced blood stem cell mobilisation in patients with chronic heart failure--Feasibility, safety and effects on exercise tolerance and cardiac function.
Basic research in cardiology 2006;101(1):78-86.
2005: Hannes Müller-Beissenhirtz; Christoph Kasper; Holger Nückel; Ulrich Dührsen
Gemcitabine, vinorelbine and prednisone for refractory or relapsed aggressive lymphoma, results of a phase II single center study.
Annals of hematology 2005;84(12):796-801.
2005: Alexander Röth; Gabriela M Baerlocher; Mike Schertzer; Liz Chavez; Ulrich Dührsen; Peter M Lansdorp
Telomere loss, senescence, and genetic instability in CD4+ T lymphocytes overexpressing hTERT.
Blood 2005;106(1):43-50.
2005: Jürgen R Novotny; Hannes Müller-Beissenhirtz; Stefan Herget-Rosenthal; Andreas Kribben; Ulrich Dührsen
Grading of symptoms in hyperleukocytic leukaemia: a clinical model for the role of different blast types and promyelocytes in the development of leukostasis syndrome.
European journal of haematology 2005;74(6):501-10.
2005: Holger Nückel; Ulrich H Frey; Alexander Röth; Ulrich Dührsen; Winfried Siffert
Alemtuzumab induces enhanced apoptosis in vitro in B-cells from patients with chronic lymphocytic leukemia by antibody-dependent cellular cytotoxicity.
European journal of pharmacology 2005;514(2-3):217-24.
2005: Roland Schroers; Frank Griesinger; Lorenz Trümper; Detlef Haase; Bettina Kulle; Ludger Klein-Hitpass; Ludger Sellmann; Ulrich Dührsen; Jan Dürig
Combined analysis of ZAP-70 and CD38 expression as a predictor of disease progression in B-cell chronic lymphocytic leukemia.
Leukemia 2005;19(5):750-8.
2005: Georg Lenz; Martin Dreyling; Eva Hoster; Bernhard Wörmann; Ulrich Dührsen; Bernd Metzner; Hartmut Eimermacher; Andreas Neubauer; Hannes Wandt; Hjalmar Steinhauer; Sonja Martin; Else Heidemann; Ali Aldaoud; Reza Parwaresch; Joerg Hasford; Michael Unterhalt; Wolfgang Hiddemann
Immunochemotherapy with rituximab and cyclophosphamide, doxorubicin, vincristine, and prednisone significantly improves response and time to treatment failure, but not long-term outcome in patients with previously untreated mantle cell lymphoma: results of a prospective randomized trial of the German Low Grade Lymphoma Study Group (GLSG).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(9):1984-92.
2005: Holger Nückel; Vera Rebmann; Jan Dürig; Ulrich Dührsen; Hans Grosse-Wilde
HLA-G expression is associated with an unfavorable outcome and immunodeficiency in chronic lymphocytic leukemia.
Blood 2005;105(4):1694-8.
2005: Jürgen R Novotny; U Schmücker; B Staats; Ulrich Dührsen
Failed or inadequate bone marrow aspiration: a fast, simple and cost-effective method to produce a cell suspension from a core biopsy specimen.
Clinical and laboratory haematology 2005;27(1):33-40.
2004: Holger Nückel; Ulrich H Frey; Jan Dürig; Ulrich Dührsen; Winfried Siffert
Methylenetetrahydrofolate reductase (MTHFR) gene 677C>T and 1298A>C polymorphisms are associated with differential apoptosis of leukemic B cells in vitro and disease progression in chronic lymphocytic leukemia.
Leukemia 2004;18(11):1816-23.
2004: Holger Nückel; Daniel Meller; Klaus-Peter Steuhl; Ulrich Dührsen
Anti-CD20 monoclonal antibody therapy in relapsed MALT lymphoma of the conjunctiva.
European journal of haematology 2004;73(4):258-62.
2004: Roland Schroers; Tobias Pukrop; Jan Dürig; Detlef Haase; Ulrich Dührsen; Lorenz Trümper; Frank Griesinger
B-cell chronic lymphocytic leukemia with aberrant CD8 expression: genetic and immunophenotypic analysis of prognostic factors.
Leukemia & lymphoma 2004;45(8):1677-81.
2004: Jürgen R Novotny; C Rosenthal; Ahmet H Elmaagacli; Jan Dürig; D W Beelen; Ulrich Dührsen
Disease- or therapy-related bone marrow damage cannot be overcome by changes in stem cell source or dose in allogeneic transplantation.
European journal of haematology 2004;73(1):1-9.
2004: Holger Nückel; Ulrich H Frey; Jan Dürig; Ulrich Dührsen; Winfried Siffert
1513A/C polymorphism in the P2X7 receptor gene in chronic lymphocytic leukemia: absence of correlation with clinical outcome.
European journal of haematology 2004;72(4):259-63.
2004: C Mozek; J Novotny; Ulrich Dührsen; K A Metz
[Lymphadenopathy in the groin. Unusual etiology in a 65-year-old patient].
Der Internist 2004;45(1):90-2.
2003: Jan Dürig; Holger Nückel; M Cremer; Anja Führer; Katja Halfmeyer; J Fandrey; Tarik Möröy; Ludger Klein-Hitpass; Ulrich Dührsen
ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia.
Leukemia 2003;17(12):2426-34.
2003: Holger Nückel; Ulrich H Frey; Nese Aralh; Jan Dürig; Ulrich Dührsen; Winfried Siffert
The CC genotype of the C825T polymorphism of the G protein beta3 gene (GNB3) is associated with a high relapse rate in patients with chronic lymphocytic leukaemia.
Leukemia & lymphoma 2003;44(10):1739-43.
2003: Andreas Hüttmann; Chung-Leung Li; Ulrich Dührsen
Bone marrow-derived stem cells and "plasticity".
Annals of hematology 2003;82(10):599-604.
2003: Silvia Deaglio; Andrea Capobianco; Luciana Bergui; Jan Dürig; Fortunato Morabito; Ulrich Dührsen; Fabio Malavasi
CD38 is a signaling molecule in B-cell chronic lymphocytic leukemia cells.
Blood 2003;102(6):2146-55.
2003: Holger Nückel; Jan Dürig; Ulrich Dührsen
Salvage chemotherapy according to the ASHAP protocol: a single-center study of 24 patients with relapsed or refractory aggressive non-Hodgkin's lymphomas.
Annals of hematology 2003;82(8):481-6.
2003: Jan Dürig; Holger Nückel; Andreas Hüttmann; Elisabeth Kruse; Tanja Hölter; Katja Halfmeyer; Anja Führer; Roland Rudolph; Naser Kalhori; Arnd Nusch; Silvia Deaglio; Fabio Malavasi; Tarik Möröy; Ludger Klein-Hitpass; Ulrich Dührsen
Expression of ribosomal and translation-associated genes is correlated with a favorable clinical course in chronic lymphocytic leukemia.
Blood 2003;101(7):2748-55.
2002: B Junge; W Popp; S Ruehm; A W Rettenmeier; Ulrich Dührsen; Michael Rünzi
Fire eater's risk: lipoid pneumonia following aspiration of a liquid hydrocarbon mixture.
Pneumologie (Stuttgart, Germany) 2002;56(9):547-9.
2002: Holger Karsunky; Hui Zeng; Thorsten Schmidt; Branko Zevnik; Reinhart Kluge; Kurt W Schmid; Ulrich Dührsen; Tarik Möröy
Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1.
Nature genetics 2002;30(3):295-300.
2002: Ulrich Dührsen
The clinical value of erythropoietin in patients with cancer.
Drugs 2002;62(14):2013-23.
2002: Alexander Schneider; Clemens Von Birgelen; Ulrich Dührsen; Guido Gerken; Michael Rünzi
Two cases of pancreatic tuberculosis in nonimmunocompromised patients. A diagnostic challenge and a rare cause of portal hypertension.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2002;2(1):69-73.
2002: Jan Dürig; M Naschar; U Schmücker; K Renzing-Köhler; Tanja Hölter; Andreas Hüttmann; Ulrich Dührsen
CD38 expression is an important prognostic marker in chronic lymphocytic leukaemia.
Leukemia 2002;16(1):30-5.
2001: Jan Dürig; U Schmücker; Ulrich Dührsen
Differential expression of chemokine receptors in B cell malignancies.
Leukemia 2001;15(5):752-6.
2001: Jan Dürig; A Giese; U Schmücker; Hans A Kretzschmar; Ulrich Dührsen
Decreased prion protein expression in human peripheral blood leucocytes from patients with paroxysmal nocturnal haemoglobinuria.
British journal of haematology 2001;112(3):658-62.
2001: Ulrich Dührsen; T Martinez; Gaby Vohwinkel; Süleyman Ergün; L Sun; G McMahon; Jan Dürig; Dieter K Hossfeld; Walter Fiedler
Effects of vascular endothelial and platelet-derived growth factor receptor inhibitors on long-term cultures from normal human bone marrow.
Growth factors (Chur, Switzerland) 2001;19(1):1-17.
2000: Jan Dürig; C Rosenthal; Katja Halfmeyer; Martin Wiemann; J Novotny; Dieter Bingmann; Ulrich Dührsen; K Schirrmacher
Intercellular communication between bone marrow stromal cells and CD34+ haematopoietic progenitor cells is mediated by connexin 43-type gap junctions.
British journal of haematology 2000;111(2):416-25.
2000: Jan Dürig; C Rosenthal; Ahmet H Elmaagacli; Clare Heyworth; Katja Halfmeyer; Christoph Kasper; J Novotny; Ulrich Dührsen
Biological effects of stroma-derived factor-1 alpha on normal and CML CD34+ haemopoietic cells.
Leukemia 2000;14(9):1652-60.
2000: Jan Dürig; A Giese; W Schulz-Schaeffer; C Rosenthal; U Schmücker; Jan Bieschke; Ulrich Dührsen; Hans A Kretzschmar
Differential constitutive and activation-dependent expression of prion protein in human peripheral blood leucocytes.
British journal of haematology 2000;108(3):488-95.
1999: W Zhang; G Knieling; Gaby Vohwinkel; T Martinez; Rolf Kuse; Dieter K Hossfeld; Ulrich Dührsen
Origin of stroma cells in long-term bone marrow cultures from patients with acute myeloid leukemia.
Annals of hematology 1999;78(7):305-14.