FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Ashley Dunn

Research Profile

Living Beings

Chemicals & Drugs

Concepts & Ideas

Molecular Sequence Data

Genes & Molecular Sequences

Amino Acid Sequences

Anatomy

Phenomena

Phosphorylation

Physiology

Signal Transduction

Co-author Network

Publications

TOP 3
Ashley R Dunn; Peiying Chuan; Zev Bryant; James A Spudich
Contribution of the myosin VI tail domain to processive stepping and intramolecular tension sensing.
Sunanda Basu; Cathy Quilici; Hui-Hua Zhang; Dianne Grail; Ashley R Dunn
Mice lacking both G-CSF and IL-6 are more susceptible to Candida albicans infection: critical role of neutrophils in defense against Candida albicans.
Hui-Hua Zhang; Sunanda Basu; Fenqiang Wu; C Glenn Begley; Christiaan J M Saris; Ashley R Dunn; Antony W Burgess; Francesca Walker
Macrophage-colony stimulating factor is required for the production of neutrophil-promoting activity by mouse embryo fibroblasts deficient in G-CSF and GM-CSF.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Ashley Dunn (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2010: Ashley R Dunn; Peiying Chuan; Zev Bryant; James A Spudich
Contribution of the myosin VI tail domain to processive stepping and intramolecular tension sensing.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(17):7746-50.
2008: Sunanda Basu; Cathy Quilici; Hui-Hua Zhang; Dianne Grail; Ashley R Dunn
Mice lacking both G-CSF and IL-6 are more susceptible to Candida albicans infection: critical role of neutrophils in defense against Candida albicans.
Growth factors (Chur, Switzerland) 2008;26(1):23-34.
2007: Hui-Hua Zhang; Sunanda Basu; Fenqiang Wu; C Glenn Begley; Christiaan J M Saris; Ashley R Dunn; Antony W Burgess; Francesca Walker
Macrophage-colony stimulating factor is required for the production of neutrophil-promoting activity by mouse embryo fibroblasts deficient in G-CSF and GM-CSF.
Journal of leukocyte biology 2007;82(4):915-25.
2007: Margaret L Hibbs; Cathy Quilici; Nicole Kountouri; John F Seymour; Jane E Armes; Antony W Burgess; Ashley R Dunn
Mice lacking three myeloid colony-stimulating factors (G-CSF, GM-CSF, and M-CSF) still produce macrophages and granulocytes and mount an inflammatory response in a sterile model of peritonitis.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6435-43.
2004: Sunanda Basu; Hui-Hua Zhang; Cathy Quilici; Ashley R Dunn
Candida albicans can stimulate stromal cells resulting in enhanced granulopoiesis.
Stem cells and development 2004;13(1):39-50.
2002: Margaret L Hibbs; Kenneth W Harder; Jane E Armes; Nicole Kountouri; Cathy Quilici; Franca Casagranda; Ashley R Dunn; David M Tarlinton
Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity.
The Journal of experimental medicine 2002;196(12):1593-604.
2002: Brendan J Jenkins; Cathy Quilici; Andrew W Roberts; Dianne Grail; Ashley R Dunn; Matthias Ernst
Hematopoietic abnormalities in mice deficient in gp130-mediated STAT signaling.
Experimental hematology 2002;30(11):1248-56.
2002: Matthias Ernst; Melissa Inglese; Glen M Scholz; Kenneth W Harder; Fiona J Clay; Steven Bozinovski; Paul Waring; Rima Darwiche; Tom Kay; Peter Sly; Rachel Collins; Debra Turner; Margaret L Hibbs; Gary P Anderson; Ashley R Dunn
Constitutive activation of the SRC family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune response.
The Journal of experimental medicine 2002;196(5):589-604.
2002: Sunanda Basu; George Hodgson; Melissa Katz; Ashley R Dunn
Evaluation of role of G-CSF in the production, survival, and release of neutrophils from bone marrow into circulation.
Blood 2002;100(3):854-61.
2002: Raffi Gugasyan; Cathy Quilici; Stacey T T I; Dianne Grail; Anne M Verhagen; Andrew Roberts; Toshio Kitamura; Ashley R Dunn; Peter Lock
Dok-related protein negatively regulates T cell development via its RasGTPase-activating protein and Nck docking sites.
The Journal of cell biology 2002;158(1):115-25.
2001: Kenneth W Harder; L M Parsons; Jane E Armes; N Evans; Nicole Kountouri; R Clark; Cathy Quilici; Dianne Grail; George Hodgson; Ashley R Dunn; Margaret L Hibbs
Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineage.
Immunity 2001;15(4):603-15.
2001: Glen M Scholz; Steven D Hartson; Kellie Cartledge; L Volk; Robert L Matts; Ashley R Dunn
The molecular chaperone Hsp90 is required for signal transduction by wild-type Hck and maintenance of its constitutively active counterpart.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2001;12(8):409-17.
2001: Matthias Ernst; Melissa Inglese; Paul Waring; Ian K Campbell; S Bao; Fiona J Clay; W S Alexander; Ian P Wicks; David M Tarlinton; Ulrike Novak; Joan K Heath; Ashley R Dunn
Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation.
The Journal of experimental medicine 2001;194(2):189-203.
2000: LS Quek; JM Pasquet; I Hers; Richard J Cornall; G Knight; M Barnes; Margaret L Hibbs; Ashley R Dunn; C A Lowell; Steve P Watson
Fyn and Lyn phosphorylate the Fc receptor gamma chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway.
Blood 2000;96(13):4246-53.
2000: T M Johnson; Nicholas A Williamson; Glen M Scholz; Anthony Jaworowski; Richard E H Wettenhall; Ashley R Dunn; Heung-Chin Cheng
Modulation of the catalytic activity of the Src family tyrosine kinase Hck by autophosphorylation at a novel site in the unique domain.
The Journal of biological chemistry 2000;275(43):33353-64.
2000: Glen M Scholz; Steven D Hartson; Kellie Cartledge; N Hall; J Shao; Ashley R Dunn; Robert L Matts
p50(Cdc37) can buffer the temperature-sensitive properties of a mutant of Hck.
Molecular and cellular biology 2000;20(18):6984-95.
2000: Kellie Cartledge; Ashley R Dunn; Glen M Scholz
Generation and characterization of monoclonal antibodies to the Src-family kinase Hck.
Hybridoma 2000;19(4):323-30.
2000: Sunanda Basu; George Hodgson; Hui-Hua Zhang; M Katz; Cathy Quilici; Ashley R Dunn
"Emergency" granulopoiesis in G-CSF-deficient mice in response to Candida albicans infection.
Blood 2000;95(12):3725-33.
2000: Glen M Scholz; Kellie Cartledge; Ashley R Dunn
Hck enhances the adherence of lipopolysaccharide-stimulated macrophages via Cbl and phosphatidylinositol 3-kinase.
The Journal of biological chemistry 2000;275(19):14615-23.
1999: Peter Lock; Franca Casagranda; Ashley R Dunn
Independent SH2-binding sites mediate interaction of Dok-related protein with RasGTPase-activating protein and Nck.
The Journal of biological chemistry 1999;274(32):22775-84.
1999: Matthias Ernst; Ulrike Novak; Sandra E Nicholson; Judith E Layton; Ashley R Dunn
The carboxyl-terminal domains of gp130-related cytokine receptors are necessary for suppressing embryonic stem cell differentiation. Involvement of STAT3.
The Journal of biological chemistry 1999;274(14):9729-37.
1999: Yifan Zhan; Sunanda Basu; GJ Lieschke; Dianne Grail; Ashley R Dunn; Christina Cheers
Functional deficiencies of peritoneal cells from gene-targeted mice lacking G-CSF or GM-CSF.
Journal of leukocyte biology 1999;65(2):256-64.
1998: Ian K Campbell; MJ Rich; Robert J Bischof; Ashley R Dunn; Dianne Grail; John A Hamilton
Protection from collagen-induced arthritis in granulocyte-macrophage colony-stimulating factor-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(7):3639-44.
1998: R J Sicilia; Margaret L Hibbs; P A Bello; Jeffrey D Bjorge; Donald J Fujita; I J Stanley; Ashley R Dunn; Heung-Chin Cheng
Common in vitro substrate specificity and differential Src homology 2 domain accessibility displayed by two members of the Src family of protein-tyrosine kinases, c-Src and Hck.
The Journal of biological chemistry 1998;273(27):16756-63.
1998: Richard J Cornall; Jason G Cyster; Margaret L Hibbs; Ashley R Dunn; KL Otipoby; Edward A Clark; Christopher C Goodnow
Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection.
Immunity 1998;8(4):497-508.
1998: Yifan Zhan; GJ Lieschke; Dianne Grail; Ashley R Dunn; Christina Cheers
Essential roles for granulocyte-macrophage colony-stimulating factor (GM-CSF) and G-CSF in the sustained hematopoietic response of Listeria monocytogenes-infected mice.
Blood 1998;91(3):863-9.
1997: John F Seymour; GJ Lieschke; Dianne Grail; Cathy Quilici; George Hodgson; Ashley R Dunn
Mice lacking both granulocyte colony-stimulating factor (CSF) and granulocyte-macrophage CSF have impaired reproductive capacity, perturbed neonatal granulopoiesis, lung disease, amyloidosis, and reduced long-term survival.
Blood 1997;90(8):3037-49.
1997: Fiona J Clay; M R Ernst; J W Trueman; R Flegg; Ashley R Dunn
The mouse Plk gene: structural characterization, chromosomal localization and identification of a processed Plk pseudogene.
Gene 1997;198(1-2):329-39.
1997: Sunanda Basu; Ashley R Dunn; MW Marino; H Savoia; George Hodgson; GJ Lieschke; Jonathan Cebon
Increased tolerance to endotoxin by granulocyte-macrophage colony-stimulating factor-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(3):1412-7.
1997: A R Gendall; Ashley R Dunn; Matthias Ernst
Isolation and characterization of a leukemia inhibitory factor-independent embryonic stem cell line.
The international journal of biochemistry & cell biology 1997;29(5):829-40.
1997: Margaret L Hibbs; Ashley R Dunn
Lyn, a src-like tyrosine kinase.
The international journal of biochemistry & cell biology 1997;29(3):397-400.
1997: David Vremec; GJ Lieschke; Ashley R Dunn; Lorraine Robb; Donald Metcalf; Ken Shortman
The influence of granulocyte/macrophage colony-stimulating factor on dendritic cell levels in mouse lymphoid organs.
European journal of immunology 1997;27(1):40-4.
1996: J F Seymour; Ashley R Dunn; J M Vincent; J J Presneill; M C Pain
Efficacy of granulocyte-macrophage colony-stimulating factor in acquired alveolar proteinosis.
The New England journal of medicine 1996;335(25):1924-5.
1996: M Ernst; Andrew Oates; Ashley R Dunn
Gp130-mediated signal transduction in embryonic stem cells involves activation of Jak and Ras/mitogen-activated protein kinase pathways.
The Journal of biological chemistry 1996;271(47):30136-43.
1996: Donald Metcalf; Lorraine Robb; Ashley R Dunn; Sandra Mifsud; Ladina Di Rago
Role of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in the development of an acute neutrophil inflammatory response in mice.
Blood 1996;88(10):3755-64.
1996: Warren S Alexander; Andrew W Roberts; A B Maurer; Nicos A Nicola; Ashley R Dunn; Donald Metcalf
Studies of the c-Mpl thrombopoietin receptor through gene disruption and activation.
Stem cells (Dayton, Ohio) 1996;14 Suppl 1():124-32.
1995: N Sotirellis; T M Johnson; Margaret L Hibbs; I J Stanley; E Stanley; Ashley R Dunn; Heung-Chin Cheng
Autophosphorylation induces autoactivation and a decrease in the Src homology 2 domain accessibility of the Lyn protein kinase.
The Journal of biological chemistry 1995;270(50):29773-80.
1995: Warren S Alexander; Donald Metcalf; Ashley R Dunn
Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity.
The EMBO journal 1995;14(22):5569-78.
1995: Margaret L Hibbs; David M Tarlinton; J Armes; Dianne Grail; George Hodgson; R Maglitto; Steven A Stacker; Ashley R Dunn
Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease.
Cell 1995;83(2):301-11.
1995: S K Nilsson; GJ Lieschke; C C Garcia-Wijnen; B Williams; D Tzelepis; George Hodgson; Dianne Grail; Ashley R Dunn; Ivan Bertoncello
Granulocyte-macrophage colony-stimulating factor is not responsible for the correction of hematopoietic deficiencies in the maturing op/op mouse.
Blood 1995;86(1):66-72.
1995: Margaret L Hibbs; E Stanley; R Maglitto; Ashley R Dunn
Identification of a duplication of the mouse Lyn gene.
Gene 1995;156(2):175-81.
1995: GJ Lieschke; Ashley R Dunn
Development of functional macrophages from embryonal stem cells in vitro.
Experimental hematology 1995;23(4):328-34.
1995: Warren S Alexander; Ashley R Dunn
Structure and transcription of the genomic locus encoding murine c-Mpl, a receptor for thrombopoietin.
Oncogene 1995;10(4):795-803.
1994: GJ Lieschke; Dianne Grail; George Hodgson; Donald Metcalf; E Stanley; Christina Cheers; K J Fowler; Sunanda Basu; Yifan Zhan; Ashley R Dunn
Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization.
Blood 1994;84(6):1737-46.
1994: GJ Lieschke; E Stanley; Dianne Grail; George Hodgson; V Sinickas; J A Gall; R A Sinclair; Ashley R Dunn
Mice lacking both macrophage- and granulocyte-macrophage colony-stimulating factor have macrophages and coexistent osteopetrosis and severe lung disease.
Blood 1994;84(1):27-35.
1994: E Stanley; GJ Lieschke; Dianne Grail; Donald Metcalf; George Hodgson; J A Gall; Darryl W Maher; Jonathan Cebon; V Sinickas; Ashley R Dunn
Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(12):5592-6.
1994: M Ernst; D P Gearing; Ashley R Dunn
Functional and biochemical association of Hck with the LIF/IL-6 receptor signal transducing subunit gp130 in embryonic stem cells.
The EMBO journal 1994;13(7):1574-84.
1994: Ashley R Dunn; G B Mann; K J Fowler; Dianne Grail; Margaret L Hibbs; Warren S Alexander; Francesca Walker; Antony W Burgess
Insights into the physiology of TGF alpha and signaling through the EGF receptor revealed by gene targeting and acts of nature.
Princess Takamatsu symposia 1994;24():276-89.
1993: G B Mann; K J Fowler; Dianne Grail; Ashley R Dunn
Identification of germ-line chimaeras by polymerase chain reaction and isoenzyme analysis of mouse spermatozoa.
Journal of reproduction and fertility 1993;99(2):505-12.
1993: K J Fowler; G B Mann; Ashley R Dunn
Linkage of the murine transforming growth factor alpha gene with Igk, Ly-2, and Fabp1 on chromosome 6.
Genomics 1993;16(3):782-4.
1993: F J Clay; S J McEwen; I Bertoncello; Andrew Wilks; Ashley R Dunn
Identification and cloning of a protein kinase-encoding mouse gene, Plk, related to the polo gene of Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(11):4882-6.
1993: G B Mann; K J Fowler; A Gabriel; Edouard C Nice; R L Williams; Ashley R Dunn
Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation.
Cell 1993;73(2):249-61.
1992: I Boulet; S Ralph; E Stanley; P Lock; Ashley R Dunn; S P Green; Wayne A Phillips
Lipopolysaccharide- and interferon-gamma-induced expression of hck and lyn tyrosine kinases in murine bone marrow-derived macrophages.
Oncogene 1992;7(4):703-10.
1992: Richard Lang; R A Cuthbertson; Ashley R Dunn
TNF alpha, IL-1 alpha and bFGF are implicated in the complex disease of GM-CSF transgenic mice.
Growth factors (Chur, Switzerland) 1992;6(2):131-8.
1991: P Lock; S Ralph; E Stanley; I Boulet; R Ramsay; Ashley R Dunn
Two isoforms of murine hck, generated by utilization of alternative translational initiation codons, exhibit different patterns of subcellular localization.
Molecular and cellular biology 1991;11(9):4363-70.
1991: E Stanley; S Ralph; S McEwen; I Boulet; D A Holtzman; P Lock; Ashley R Dunn
Alternatively spliced murine lyn mRNAs encode distinct proteins.
Molecular and cellular biology 1991;11(7):3399-406.
1990: P Lock; E Stanley; D A Holtzman; Ashley R Dunn
Functional analysis and nucleotide sequence of the promoter region of the murine hck gene.
Molecular and cellular biology 1990;10(9):4603-11.
1990: Ashley R Dunn; Andrew Wilks
Contributions of autocrine and non-autocrine mechanisms to tumorigenicity in a murine model for leukaemia.
Ciba Foundation symposium 1990;148():145-55; discussion 155-7.
1989: Peter Sobieszczuk; Thomas J Gonda; Ashley R Dunn
Structure and biological activity of the transcriptional initiation sequences of the murine c-myb oncogene.
Nucleic acids research 1989;17(23):9593-611.
1989: Andrew Wilks; R R Kurban; Ashley R Dunn
Direct demonstration of an autocrine mechanism in EMS-induced, tumorigenic mutants of the growth factor-dependent hemopoietic cell line, FDC-P1.
Growth factors (Chur, Switzerland) 1989;2(1):31-42.
1987: N M Gough; J A King; Ashley R Dunn
An mRNA sharing sequences with a variant granulocyte-macrophage colony stimulating factor cDNA clone.
Nucleic acids research 1987;15(24):10584.
1987: Donald Metcalf; Thomas M Roberts; V Cherington; Ashley R Dunn
The in vitro behavior of hemopoietic cells transformed by polyoma middle T antigen parallels that of primary human myeloid leukemic cells.
The EMBO journal 1987;6(12):3703-9.
1987: D A Holtzman; W D Cook; Ashley R Dunn
Isolation and sequence of a cDNA corresponding to a src-related gene expressed in murine hemopoietic cells.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(23):8325-9.
1987: Ashley R Dunn
The role of growth factors in normal and neoplastic haemopoiesis.
Annals of the New York Academy of Sciences 1987;511():1-9.
1985: Richard Lang; Donald Metcalf; N M Gough; Ashley R Dunn; Thomas J Gonda
Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity.
Cell 1985;43(2 Pt 1):531-42.
1985: E Stanley; D Metcalf; Peter Sobieszczuk; N M Gough; Ashley R Dunn
The structure and expression of the murine gene encoding granulocyte-macrophage colony stimulating factor: evidence for utilisation of alternative promoters.
The EMBO journal 1985;4(10):2569-73.
1985: Thomas J Gonda; N M Gough; Ashley R Dunn; J de Blaquiere
Nucleotide sequence of cDNA clones of the murine myb proto-oncogene.
The EMBO journal 1985;4(8):2003-8.
1985: N M Gough; D Metcalf; J Gough; Dianne Grail; Ashley R Dunn
Structure and expression of the mRNA for murine granulocyte-macrophage colony stimulating factor.
The EMBO journal 1985;4(3):645-53.
1985: N M Gough; J Gough; D Metcalf; A Kelso; Dianne Grail; N A Nicola; Ashley R Dunn
Cloning and expression of the gene for murine granulocyte-macrophage colony-stimulating factor.
Haematology and blood transfusion 1985;29():380-4.
1984: N M Gough; J Gough; D Metcalf; A Kelso; Dianne Grail; N A Nicola; Antony W Burgess; Ashley R Dunn
Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte-macrophage colony stimulating factor.
Nature 1984;309(5971):763-7.