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Sirio Dupont

Research Profile

Chemicals & Drugs

Physiology

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TOP 3
A Mamidi; A Manfrin; Sandra Soligo; Oliver Wessely; M Aragona; Michelangelo Cordenonsi; Sirio Dupont; E Enzo; M Inui; Stefano Piccolo
Signaling crosstalk between TGFβ and Dishevelled/Par1b.
Masafumi Inui; Andrea Manfrin; Graziano Martello; Marco Montagner; Mariaceleste Aragona; Luca Azzolin; Danny Ben-Zvi; Michelangelo Cordenonsi; Sirio Dupont; Elena Enzo; Sandra Soligo; Luca Zacchigna; Francesca Zanconato; Stefano Piccolo
Self-regulation of the head-inducing properties of the Spemann organizer.
Sirio Dupont; Masafumi Inui; Stuart J Newfeld
Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads.

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All Publications

2012: A Mamidi; A Manfrin; Sandra Soligo; Oliver Wessely; M Aragona; Michelangelo Cordenonsi; Sirio Dupont; E Enzo; M Inui; Stefano Piccolo
Signaling crosstalk between TGFβ and Dishevelled/Par1b.
Cell death and differentiation 2012;19(10):1689-97.
2012: Masafumi Inui; Andrea Manfrin; Graziano Martello; Marco Montagner; Mariaceleste Aragona; Luca Azzolin; Danny Ben-Zvi; Michelangelo Cordenonsi; Sirio Dupont; Elena Enzo; Sandra Soligo; Luca Zacchigna; Francesca Zanconato; Stefano Piccolo
Self-regulation of the head-inducing properties of the Spemann organizer.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(38):15354-9.
2012: Sirio Dupont; Masafumi Inui; Stuart J Newfeld
Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads.
FEBS letters 2012;586(14):1913-20.
2011: Michelangelo Cordenonsi; Maria Grazia Daidone; Sirio Dupont; Mattia Forcato; Chiara Frasson; Masafumi Inui; Marco Montagner; Anna Parenti; Luca Azzolin; Giuseppe Basso; Silvio Bicciato; Alessandro Poletti; Antonio Rosato; Francesca Zanconato; Stefano Piccolo
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells.
Cell 2011;147(4):759-72.
2011: Masafumi Inui; Anant Mamidi; Andrea Manfrin; Graziano Martello; Stefano Moro; Leonardo Morsut; Michelangelo Cordenonsi; Sirio Dupont; Elena Enzo; Simona Polo; Sandra Soligo; Stefano Piccolo
USP15 is a deubiquitylating enzyme for receptor-activated SMADs.
Nature cell biology 2011;13(11):1368-75.
2011: Sirio Dupont; Nicola Elvassore; Elena Enzo; Mattia Forcato; Stefano Giulitti; Jimmy Le Digabel; Leonardo Morsut; Mariaceleste Aragona; Silvio Bicciato; Michelangelo Cordenonsi; Francesca Zanconato; Stefano Piccolo
Role of YAP/TAZ in mechanotransduction.
Nature 2011;474(7350):179-83.
2010: Leonardo Morsut; Kai-Ping Yan; Elena Enzo; Mariaceleste Aragona; Sandra M Soligo; Olivia Wendling; Manuel Mark; Konstantin Khetchoumian; Giorgio M Bressan; Pierre Chambon; Sirio Dupont; Régine Losson; Stefano Piccolo
Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo.
Development (Cambridge, England) 2010;137(15):2571-8.
2010: Graziano Martello; Antonio Rosato; Francesco Ferrari; Andrea Manfrin; Michelangelo Cordenonsi; Sirio Dupont; Elena Enzo; Vincenza Guzzardo; Maria Rondina; Thomas Spruce; Anna Parenti; Maria Grazia Daidone; Silvio Bicciato; Stefano Piccolo
A MicroRNA targeting dicer for metastasis control.
Cell 2010;141(7):1195-207.
2009: Maddalena Adorno; Michelangelo Cordenonsi; Marco Montagner; Sirio Dupont; Christine Wong; Byron Hann; Aldo Solari; Sara Bobisse; Maria Beatrice Rondina; Vincenza Guzzardo; Anna Parenti; Antonio Rosato; Silvio Bicciato; Allan Balmain; Stefano Piccolo
A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis.
Cell 2009;137(1):87-98.
2009: Sirio Dupont; Anant Mamidi; Michelangelo Cordenonsi; Marco Montagner; Luca Zacchigna; Maddalena Adorno; Graziano Martello; Michael J Stinchfield; Sandra Soligo; Leonardo Morsut; Masafumi Inui; Stefano Moro; Nicola Modena; Francesco Argenton; Stuart J Newfeld; Stefano Piccolo
FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination.
Cell 2009;136(1):123-35.
2007: Graziano Martello; Luca Zacchigna; Masafumi Inui; Marco Montagner; Maddalena Adorno; Anant Mamidi; Leonardo Morsut; Sandra Soligo; Uyen Tran; Sirio Dupont; Michelangelo Cordenonsi; Oliver Wessely; Stefano Piccolo
MicroRNA control of Nodal signalling.
Nature 2007;449(7159):183-8.
2007: Michelangelo Cordenonsi; Marco Montagner; Maddalena Adorno; Luca Zacchigna; Graziano Martello; Anant Mamidi; Sandra Soligo; Sirio Dupont; Stefano Piccolo
Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation.
Science (New York, N.Y.) 2007;315(5813):840-3.
2006: Luca Zacchigna; Carmine Vecchione; Antonella Notte; Michelangelo Cordenonsi; Sirio Dupont; Silvia Maretto; Giuseppe Cifelli; Alessandra Ferrari; Angelo Maffei; Carla Fabbro; Paola Braghetta; Gennaro Marino; Giulio Selvetella; Alessandra Aretini; Claudio Colonnese; Umberto Bettarini; Giovanni Russo; Sandra Soligo; Maddalena Adorno; Paolo Bonaldo; Dino Volpin; Stefano Piccolo; Giuseppe Lembo; Giorgio M Bressan
Emilin1 links TGF-beta maturation to blood pressure homeostasis.
Cell 2006;124(5):929-42.
2005: Sirio Dupont; Luca Zacchigna; Michelangelo Cordenonsi; Sandra Soligo; Maddalena Adorno; Massimo Rugge; Stefano Piccolo
Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase.
Cell 2005;121(1):87-99.
2004: Sirio Dupont; Luca Zacchigna; Maddalena Adorno; Sandra Soligo; Dino Volpin; Stefano Piccolo; Michelangelo Cordenonsi
Convergence of p53 and TGF-beta signaling networks.
Cancer letters 2004;213(2):129-38.
2003: Michelangelo Cordenonsi; Sirio Dupont; Silvia Maretto; Alessandra Insinga; Carol Imbriano; Stefano Piccolo
Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads.
Cell 2003;113(3):301-14.
2003: Silvia Maretto; Michelangelo Cordenonsi; Sirio Dupont; Paola Braghetta; Vania Broccoli; Andrew Bassim Hassan; Dino Volpin; Giorgio M Bressan; Stefano Piccolo
Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3299-304.