Stephen Durham

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Durham Stephen R
Mechanisms of immunotherapy.
James L K; Durham S R
Update on mechanisms of allergen injection immunotherapy.
Radulovic Suzana; Jacobson Mikila R; Durham Stephen R; Nouri-Aria Kayhan T
Grass pollen immunotherapy induces Foxp3-expressing CD4+ CD25+ cells in the nasal mucosa.

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All Publications

2008: Durham Stephen R
Mechanisms of immunotherapy.
Drugs of today (Barcelona, Spain : 1998) 2008;44 Suppl B():93-4.
2008: James L K; Durham S R
Update on mechanisms of allergen injection immunotherapy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008;38(7):1074-88.
2008: Radulovic Suzana; Jacobson Mikila R; Durham Stephen R; Nouri-Aria Kayhan T
Grass pollen immunotherapy induces Foxp3-expressing CD4+ CD25+ cells in the nasal mucosa.
The Journal of allergy and clinical immunology 2008;121(6):1467-72, 1472.e1.
2008: Francis J N; Sabroe I; Lloyd C M; Durham S R; Till S J
Elevated CCR6+ CD4+ T lymphocytes in tissue compared with blood and induction of CCL20 during the asthmatic late response.
Clinical and experimental immunology 2008;152(3):440-7.
2008: Francis James N; James Louisa K; Paraskevopoulos Giannis; Wong Cheukyee; Calderon Moises A; Durham Stephen R; Till Stephen J
Grass pollen immunotherapy: IL-10 induction and suppression of late responses precedes IgG4 inhibitory antibody activity.
The Journal of allergy and clinical immunology 2008;121(5):1120-1125.e2.
2008: Calderón Moisés A; Penagos Martin; Durham Stephen R
Sublingual immunotherapy for allergic Rhinoconjunctivitis, allergic asthma, and prevention of allergic diseases.
Clinical allergy and immunology 2008;21():359-75.
2008: Till Stephen J; Durham Stephen R
Immunologic responses to subcutaneous allergen immunotherapy.
Clinical allergy and immunology 2008;21():59-70.
2007: Klunker Sven; Saggar Lavina R; Seyfert-Margolis Vicki; Asare Adam L; Casale Thomas B; Durham Stephen R; Francis James N;
Combination treatment with omalizumab and rush immunotherapy for ragweed-induced allergic rhinitis: Inhibition of IgE-facilitated allergen binding.
The Journal of allergy and clinical immunology 2007;120(3):688-95.
2007: Calderon M A; Birk A O; Andersen J S; Durham S R
Prolonged preseasonal treatment phase with Grazax sublingual immunotherapy increases clinical efficacy.
Allergy 2007;62(8):958-61.
2007: Pilette Charles; Nouri-Aria Kayhan T; Jacobson Mikila R; Wilcock Louisa K; Detry Bruno; Walker Samantha M; Francis James N; Durham Stephen R
Grass pollen immunotherapy induces an allergen-specific IgA2 antibody response associated with mucosal TGF-beta expression.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4658-66.
2007: Rak Sabina; Yang William H; Pedersen Martin R; Durham Stephen R
Once-daily sublingual allergen-specific immunotherapy improves quality of life in patients with grass pollen-induced allergic rhinoconjunctivitis: a double-blind, randomised study.
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2007;16(2):191-201.
2007: Takhar Pooja; Corrigan Christopher J; Smurthwaite Lyn; O'Connor Brian J; Durham Stephen R; Lee Tak H; Gould Hannah J
Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma.
The Journal of allergy and clinical immunology 2007;119(1):213-8.
2007: Francis J N; Lloyd C M; Sabroe I; Durham S R; Till S J
T lymphocytes expressing CCR3 are increased in allergic rhinitis compared with non-allergic controls and following allergen immunotherapy.
Allergy 2007;62(1):59-65.
2006: Shamji Mohamed H; Wilcock Louisa K; Wachholz Petra A; Dearman Rebecca J; Kimber Ian; Wurtzen Peter A; Larché Mark; Durham Stephen R; Francis James N
The IgE-facilitated allergen binding (FAB) assay: validation of a novel flow-cytometric based method for the detection of inhibitory antibody responses.
Journal of immunological methods 2006;317(1-2):71-9.
2006: Gould Hannah J; Takhar Pooja; Harries Helen E; Durham Stephen R; Corrigan Christopher J
Germinal-centre reactions in allergic inflammation.
Trends in immunology 2006;27(10):446-52.
2006: Wilcock Louisa K; Francis James N; Durham Stephen R
IgE-facilitated antigen presentation: role in allergy and the influence of allergen immunotherapy.
Immunology and allergy clinics of North America 2006;26(2):333-47, viii-ix.
2006: Durham Stephen R; Yang William H; Pedersen Martin R; Johansen Niels; Rak Sabina
Sublingual immunotherapy with once-daily grass allergen tablets: a randomized controlled trial in seasonal allergic rhinoconjunctivitis.
The Journal of allergy and clinical immunology 2006;117(4):802-9.
2006: Erin E M; Leaker B R; Zacharasiewicz A; Higgins L A; Nicholson G C; Boyce M J; de Boer P; Jones R C; Durham S R; Barnes P J; Hansel T T
Effects of a reversible beta-tryptase and trypsin inhibitor (RWJ-58643) on nasal allergic responses.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2006;36(4):458-64.
2006: Jones Meinir G; Floyd Alison; Nouri-Aria Kayhan T; Jacobson Mikila R; Durham Stephen R; Taylor Anthony Newman; Cullinan Paul
Is occupational asthma to diisocyanates a non-IgE-mediated disease?
The Journal of allergy and clinical immunology 2006;117(3):663-9.
2005: Erin E M; Zacharasiewicz A S; Nicholson G C; Tan A J; Higgins L A; Williams T J; Murdoch R D; Durham S R; Barnes P J; Hansel T T
Topical corticosteroid inhibits interleukin-4, -5 and -13 in nasal secretions following allergen challenge.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(12):1608-14.
2005: Erin E M; Leaker B R; Zacharasiewicz A S; Higgins L A; Williams T J; Boyce M J; de Boer P; Durham S R; Barnes P J; Hansel T T
Single dose topical corticosteroid inhibits IL-5 and IL-13 in nasal lavage following grass pollen challenge.
Allergy 2005;60(12):1524-9.
2005: Erin E M; Neighbour H; Tan A J; Min Kon O; Durham S R; Hansel T T
Nasal testing for novel anti-inflammatory agents.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(8):981-5.
2005: Coker Heather A; Harries Helen E; Banfield Graham K; Carr Victoria A; Durham Stephen R; Chevretton Elfy; Hobby Paul; Sutton Brian J; Gould Hannah J
Biased use of VH5 IgE-positive B cells in the nasal mucosa in allergic rhinitis.
The Journal of allergy and clinical immunology 2005;116(2):445-52.
2005: Nouri-Aria Kayhan T; Pilette Charles; Jacobson Mikila R; Watanabe Hiroshi; Durham Stephen R
IL-9 and c-Kit+ mast cells in allergic rhinitis during seasonal allergen exposure: effect of immunotherapy.
The Journal of allergy and clinical immunology 2005;116(1):73-9.
2005: Takhar Pooja; Smurthwaite Lyn; Coker Heather A; Fear David J; Banfield Graham K; Carr Victoria A; Durham Stephen R; Gould Hannah J
Allergen drives class switching to IgE in the nasal mucosa in allergic rhinitis.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(8):5024-32.
2005: Rowe-Jones Julian M; Medcalf Mark; Durham Stephen R; Richards David H; Mackay Ian S
Functional endoscopic sinus surgery: 5 year follow up and results of a prospective, randomised, stratified, double-blind, placebo controlled study of postoperative fluticasone propionate aqueous nasal spray.
Rhinology 2005;43(1):2-10.
2005: Howarth Peter H; Persson Carl G A; Meltzer Eli O; Jacobson Mikila R; Durham Stephen R; Silkoff Philip E
Objective monitoring of nasal airway inflammation in rhinitis.
The Journal of allergy and clinical immunology 2005;115(3 Suppl 1):S414-41.
2005: Netuveli Gopalakrishnan; Hurwitz Brian; Levy Mark; Fletcher Monica; Barnes Greta; Durham Stephen R; Sheikh Aziz
Ethnic variations in UK asthma frequency, morbidity, and health-service use: a systematic review and meta-analysis.
Lancet 2005;365(9456):312-7.
2005: Wilson D R; Lima M Torres; Durham S R
Sublingual immunotherapy for allergic rhinitis: systematic review and meta-analysis.
Allergy 2005;60(1):4-12.
2004: Francis James N; Durham Stephen R
Adjuvants for allergen immunotherapy: experimental results and clinical perspectives.
Current opinion in allergy and clinical immunology 2004;4(6):543-8.
2004: Robinson Douglas S; Larché Mark; Durham Stephen R
Tregs and allergic disease.
The Journal of clinical investigation 2004;114(10):1389-97.
2004: Wilcock L K; Francis J N; Durham S R
Aluminium hydroxide down-regulates T helper 2 responses by allergen-stimulated human peripheral blood mononuclear cells.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(9):1373-8.
2004: Wachholz Petra A; Durham Stephen R
Mechanisms of immunotherapy: IgG revisited.
Current opinion in allergy and clinical immunology 2004;4(4):313-8.
2004: Pilette C; Francis J N; Till S J; Durham S R
CCR4 ligands are up-regulated in the airways of atopic asthmatics after segmental allergen challenge.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;23(6):876-84.
2004: Till Stephen J; Francis James N; Nouri-Aria Kayhan; Durham Stephen R
Mechanisms of immunotherapy.
The Journal of allergy and clinical immunology 2004;113(6):1025-34; quiz 1035.
2004: Nouri-Aria Kayhan T; Wachholz Petra A; Francis James N; Jacobson Mikila R; Walker Samantha M; Wilcock Louisa K; Staple Steven Q; Aalberse Robert C; Till Stephen J; Durham Stephen R
Grass pollen immunotherapy induces mucosal and peripheral IL-10 responses and blocking IgG activity.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(5):3252-9.
2004: Francis James N; Jacobson Mikila R; Lloyd Clare M; Sabroe Ian; Durham Stephen R; Till Stephen J
CXCR1+CD4+ T cells in human allergic disease.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(1):268-73.
2004: Pilette Charles; Durham Stephen R; Vaerman Jean-Pierre; Sibille Yves
Mucosal immunity in asthma and chronic obstructive pulmonary disease: a role for immunoglobulin A?
Proceedings of the American Thoracic Society 2004;1(2):125-35.
2004: Till Stephen J; Durham Stephen R
Immunological responses to allergen immunotherapy.
Clinical allergy and immunology 2004;18():85-104.
2003: Rimaniol Anne-Cécile; Till Stephen J; Garcia Gilles; Capel Francis; Godot Véronique; Balabanian Karl; Durand-Gasselin Ingrid; Varga Eva Maria; Simonneau Gerald; Emilie Dominique; Durham Stephen R; Humbert Marc
The CX3C chemokine fractalkine in allergic asthma and rhinitis.
The Journal of allergy and clinical immunology 2003;112(6):1139-46.
2003: Wachholz Petra A; Soni Nanna Kristensen; Till Stephen J; Durham Stephen R
Inhibition of allergen-IgE binding to B cells by IgG antibodies after grass pollen immunotherapy.
The Journal of allergy and clinical immunology 2003;112(5):915-22.
2003: Coker Heather A; Durham Stephen R; Gould Hannah J
Local somatic hypermutation and class switch recombination in the nasal mucosa of allergic rhinitis patients.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(10):5602-10.
2003: Watanabe H; Foo T H; Djazaeri B; Duncombe P; Mackay I S; Durham S R
Oxymetazoline nasal spray three times daily for four weeks in normal subjects is not associated with rebound congestion or tachyphylaxis.
Rhinology 2003;41(3):167-74.
2003: Robinson D S; Campbell D A; Durham S R; Pfeffer J; Barnes P J; Chung K F;
Systematic assessment of difficult-to-treat asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;22(3):478-83.
2003: Francis James N; Till Stephen J; Durham Stephen R
Induction of IL-10+CD4+CD25+ T cells by grass pollen immunotherapy.
The Journal of allergy and clinical immunology 2003;111(6):1255-61.
2003: Karagiannis Sophia N; Wang Qin; East Nick; Burke Frances; Riffard Stephane; Bracher Marguerite G; Thompson Richard G; Durham Stephen R; Schwartz Lawrence B; Balkwill Frances R; Gould Hannah J
Activity of human monocytes in IgE antibody-dependent surveillance and killing of ovarian tumor cells.
European journal of immunology 2003;33(4):1030-40.
2003: Varga Eva-Maria; Nouri-Aria Kayhan; Till Stephen J; Durham Stephen R
Immunomodulatory treatment strategies for allergic diseases.
Current drug targets. Inflammation and allergy 2003;2(1):31-46.
2003: Wilson D R; Torres L I; Durham S R
Sublingual immunotherapy for allergic rhinitis.
Cochrane database of systematic reviews (Online) 2003;(2):CD002893.
2002: Nouri-Aria Kayhan T; Wilson Duncan; Francis James N; Jopling Louise A; Jacobson Mikila R; Hodge Martin R; Andrew David P; Till Stephen J; Varga Eva-Maria; Williams Timothy J; Pease James E; Lloyd Clare M; Sabroe Ian; Durham Stephen R
CCR4 in human allergen-induced late responses in the skin and lung.
European journal of immunology 2002;32(7):1933-8.
2002: Smurthwaite Lyn; Durham Stephen R
Local IgE synthesis in allergic rhinitis and asthma.
Current allergy and asthma reports 2002;2(3):231-8.
2002: Wachholz Petra A; Nouri-Aria Kayhan T; Wilson Duncan R; Walker Samantha M; Verhoef Adrienne; Till Stephen J; Durham Stephen R
Grass pollen immunotherapy for hayfever is associated with increases in local nasal but not peripheral Th1:Th2 cytokine ratios.
Immunology 2002;105(1):56-62.
2002: Wilson Duncan R; Merrett Terry G; Varga Eva M; Smurthwaite Lyn; Gould Hannah J; Kemp Michael; Hooper James; Till Stephen J; Durham Stephen R
Increases in allergen-specific IgE in BAL after segmental allergen challenge in atopic asthmatics.
American journal of respiratory and critical care medicine 2002;165(1):22-6.
2001: Smurthwaite L; Walker S N; Wilson D R; Birch D S; Merrett T G; Durham S R; Gould H J
Persistent IgE synthesis in the nasal mucosa of hay fever patients.
European journal of immunology 2001;31(12):3422-31.
2001: Wilson D R; Irani A M; Walker S M; Jacobson M R; Mackay I S; Schwartz L B; Durham S R
Grass pollen immunotherapy inhibits seasonal increases in basophils and eosinophils in the nasal epithelium.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2001;31(11):1705-13.
2001: Nouri-Aria K T; Irani A M; Jacobson M R; O'brien F; Varga E M; Till S J; Durham S R; Schwartz L B
Basophil recruitment and IL-4 production during human allergen-induced late asthma.
The Journal of allergy and clinical immunology 2001;108(2):205-11.
2001: Wilson D R; Nouri-Aria K T; Walker S M; Pajno G B; O'Brien F; Jacobson M R; Mackay I S; Durham S R
Grass pollen immunotherapy: symptomatic improvement correlates with reductions in eosinophils and IL-5 mRNA expression in the nasal mucosa during the pollen season.
The Journal of allergy and clinical immunology 2001;107(6):971-6.
2001: Ying S; Humbert M; Meng Q; Pfister R; Menz G; Gould H J; Kay A B; Durham S R
Local expression of epsilon germline gene transcripts and RNA for the epsilon heavy chain of IgE in the bronchial mucosa in atopic and nonatopic asthma.
The Journal of allergy and clinical immunology 2001;107(4):686-92.
2001: Till S J; Jacobson M R; O'Brien F; Durham S R; KleinJan A; Fokkens W J; Juliusson S; Löwhagen O
Recruitment of CD1a+ Langerhans cells to the nasal mucosa in seasonal allergic rhinitis and effects of topical corticosteroid therapy.
Allergy 2001;56(2):126-31.
2001: Walker S M; Pajno G B; Lima M T; Wilson D R; Durham S R
Grass pollen immunotherapy for seasonal rhinitis and asthma: a randomized, controlled trial.
The Journal of allergy and clinical immunology 2001;107(1):87-93.
2000: Nouri-Aria K T; O'Brien F; Noble W; Jabcobson M R; Rajakulasingam K; Durham S R
Cytokine expression during allergen-induced late nasal responses: IL-4 and IL-5 mRNA is expressed early (at 6 h) predominantly by eosinophils.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2000;30(12):1709-16.
2000: Durham S R; Till S J; Corrigan C J
T lymphocytes in asthma: bronchial versus peripheral responses.
The Journal of allergy and clinical immunology 2000;106(5 Suppl):S221-6.
2000: Durham S R; Smurthwaite L; Gould H J
Local IgE production.
American journal of rhinology 2000;14(5):305-7.
2000: Varga E M; Wachholz P; Nouri-Aria K T; Verhoef A; Corrigan C J; Till S J; Durham S R
T cells from human allergen-induced late asthmatic responses express IL-12 receptor beta 2 subunit mRNA and respond to IL-12 in vitro.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(5):2877-85.
2000: Laberge S; Pinsonneault S; Varga E M; Till S J; Nouri-Aria K; Jacobson M; Cruikshank W W; Center D M; Hamid Q; Durham S R
Increased expression of IL-16 immunoreactivity in bronchial mucosa after segmental allergen challenge in patients with asthma.
The Journal of allergy and clinical immunology 2000;106(2):293-301.
2000: van Cauwenberge P; Bachert C; Passalacqua G; Bousquet J; Canonica G W; Durham S R; Fokkens W J; Howarth P H; Lund V; Malling H J; Mygind N; Passali D; Scadding G K; Wang D Y
Consensus statement on the treatment of allergic rhinitis. European Academy of Allergology and Clinical Immunology.
Allergy 2000;55(2):116-34.
2000: Durham S R; Walker S
Immunotherapy for hayfever.
Chemical immunology 2000;78():199-208.
1999: Durham S R; Varney V A; Gaga M; Jacobson M R; Varga E M; Frew A J; Kay A B
Grass pollen immunotherapy decreases the number of mast cells in the skin.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29(11):1490-6.
1999: Jacobson M R; Juliusson S; Löwhagen O; Balder B; Kay A B; Durham S R
Effect of topical corticosteroids on seasonal increases in epithelial eosinophils and mast cells in allergic rhinitis: a comparison of nasal brush and biopsy methods.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29(10):1347-55.
1999: Varga E M; Jacobson M R; Masuyama K; Rak S; Till S J; Darby Y; Hamid Q; Lund V; Scadding G K; Durham S R
Inflammatory cell populations and cytokine mRNA expression in the nasal mucosa in aspirin-sensitive rhinitis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(3):610-5.
1999: Durham S R; Walker S M; Varga E M; Jacobson M R; O'Brien F; Noble W; Till S J; Hamid Q A; Nouri-Aria K T
Long-term clinical efficacy of grass-pollen immunotherapy.
The New England journal of medicine 1999;341(7):468-75.
1999: Varga E M; Jacobson M R; Till S J; Masuyama K; O'Brien F; Rak S; Lund V; Scadding G K; Hamid Q A; Durham S R
Cellular infiltration and cytokine mRNA expression in perennial allergic rhinitis.
Allergy 1999;54(4):338-45.
1999: Alton E W; Stern M; Farley R; Jaffe A; Chadwick S L; Phillips J; Davies J; Smith S N; Browning J; Davies M G; Hodson M E; Durham S R; Li D; Jeffery P K; Scallan M; Balfour R; Eastman S J; Cheng S H; Smith A E; Meeker D; Geddes D M
Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trial.
Lancet 1999;353(9157):947-54.
1999: Durham S R
Effect of intranasal corticosteroid treatment on asthma in children and adults.
Allergy 1999;54 Suppl 57():124-31.
1998: Stirling R G; Kharitonov S A; Campbell D; Robinson D S; Durham S R; Chung K F; Barnes P J
Increase in exhaled nitric oxide levels in patients with difficult asthma and correlation with symptoms and disease severity despite treatment with oral and inhaled corticosteroids. Asthma and Allergy Group.
Thorax 1998;53(12):1030-4.
1998: Durham S R
The inflammatory nature of allergic disease.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28 Suppl 6():20-4.
1998: Kotsimbos T C; Ghaffar O; Minshall E M; Humbert M; Durham S R; Pfister R; Menz G; Kay A B; Hamid Q A
Expression of the IL-4 receptor alpha-subunit is increased in bronchial biopsy specimens from atopic and nonatopic asthmatic subjects.
The Journal of allergy and clinical immunology 1998;102(5):859-66.
1998: Masuyama K; Till S J; Jacobson M R; Kamil A; Cameron L; Juliusson S; Lowhagen O; Kay A B; Hamid Q A; Durham S R
Nasal eosinophilia and IL-5 mRNA expression in seasonal allergic rhinitis induced by natural allergen exposure: effect of topical corticosteroids.
The Journal of allergy and clinical immunology 1998;102(4 Pt 1):610-7.
1998: Gaga M; Bentley A M; Humbert M; Barkans J; O'Brien F; Wathen C G; Kay A B; Durham S R
Increases in CD4+ T lymphocytes, macrophages, neutrophils and interleukin 8 positive cells in the airways of patients with bronchiectasis.
Thorax 1998;53(8):685-91.
1998: Durham S R; Till S J
Immunologic changes associated with allergen immunotherapy.
The Journal of allergy and clinical immunology 1998;102(2):157-64.
1998: Till S J; Durham S R; Rajakulasingam K; Humbert M; Huston D; Dickason R; Kay A B; Corrigan C J
Allergen-induced proliferation and interleukin-5 production by bronchoalveolar lavage and blood T cells after segmental allergen challenge.
American journal of respiratory and critical care medicine 1998;158(2):404-11.
1998: Rajakulasingam K; Till S; Ying S; Humbert M; Barkans J; Sullivan M; Meng Q; Corrigan C J; Bungre J; Grant J A; Kay A B; Durham S R
Increased expression of high affinity IgE (FcepsilonRI) receptor-alpha chain mRNA and protein-bearing eosinophils in human allergen-induced atopic asthma.
American journal of respiratory and critical care medicine 1998;158(1):233-40.
1998: Durham S R
Mechanisms of mucosal inflammation in the nose and lungs.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28 Suppl 2():11-6.
1998: Minshall E; Ghaffar O; Cameron L; O'Brien F; Quinn H; Rowe-Jones J; Davies R J; Prior A; Lund V J; Mackay I S; Nolop K; Lutsky B; Durham S R; Hamid Q
Assessment by nasal biopsy of long-term use of mometasone furoate aqueous nasal spray (Nasonex) in the treatment of perennial rhinitis.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1998;118(5):648-54.
1998: Ghaffar O; Durham S R; Al-Ghamdi K; Wright E; Small P; Frenkiel S; Gould H J; Hamid Q
Expression of IgE heavy chain transcripts in the sinus mucosa of atopic and nonatopic patients with chronic sinusitis.
American journal of respiratory cell and molecular biology 1998;18(5):706-11.
1998: Cameron L A; Durham S R; Jacobson M R; Masuyama K; Juliusson S; Gould H J; Lowhagen O; Minshall E M; Hamid Q A
Expression of IL-4, Cepsilon RNA, and Iepsilon RNA in the nasal mucosa of patients with seasonal rhinitis: effect of topical corticosteroids.
The Journal of allergy and clinical immunology 1998;101(3):330-6.
1998: Ying S; Barata L T; Meng Q; Grant J A; Barkans J; Durham S R; Kay A B
High-affinity immunoglobulin E receptor (Fc epsilon RI)-bearing eosinophils, mast cells, macrophages and Langerhans' cells in allergen-induced late-phase cutaneous reactions in atopic subjects.
Immunology 1998;93(2):281-8.
1998: Barata L T; Ying S; Meng Q; Barkans J; Rajakulasingam K; Durham S R; Kay A B
IL-4- and IL-5-positive T lymphocytes, eosinophils, and mast cells in allergen-induced late-phase cutaneous reactions in atopic subjects.
The Journal of allergy and clinical immunology 1998;101(2 Pt 1):222-30.
1998: Menz G; Ying S; Durham S R; Corrigan C J; Robinson D S; Hamid Q; Pfister R; Humbert M; Kay A B
Molecular concepts of IgE-initiated inflammation in atopic and nonatopic asthma.
Allergy 1998;53(45 Suppl):15-21.
1997: Ying S; Robinson D S; Meng Q; Rottman J; Kennedy R; Ringler D J; Mackay C R; Daugherty B L; Springer M S; Durham S R; Williams T J; Kay A B
Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co-localization of eotaxin mRNA to bronchial epithelial and endothelial cells.
European journal of immunology 1997;27(12):3507-16.
1997: Durham S R; Gould H J; Thienes C P; Jacobson M R; Masuyama K; Rak S; Lowhagen O; Schotman E; Cameron L; Hamid Q A
Expression of epsilon germ-line gene transcripts and mRNA for the epsilon heavy chain of IgE in nasal B cells and the effects of topical corticosteroid.
European journal of immunology 1997;27(11):2899-906.
1997: Laberge S; Durham S R; Ghaffar O; Rak S; Center D M; Jacobson M; Hamid Q
Expression of IL-16 in allergen-induced late-phase nasal responses and relation to topical glucocorticosteroid treatment.
The Journal of allergy and clinical immunology 1997;100(4):569-74.
1997: Humbert M; Corrigan C J; Kimmitt P; Till S J; Kay A B; Durham S R
Relationship between IL-4 and IL-5 mRNA expression and disease severity in atopic asthma.
American journal of respiratory and critical care medicine 1997;156(3 Pt 1):704-8.
1997: Rajakulasingam K; Durham S R; O'Brien F; Humbert M; Barata L T; Reece L; Kay A B; Grant J A
Enhanced expression of high-affinity IgE receptor (Fc epsilon RI) alpha chain in human allergen-induced rhinitis with co-localization to mast cells, macrophages, eosinophils, and dendritic cells.
The Journal of allergy and clinical immunology 1997;100(1):78-86.
1997: Ghaffar O; Laberge S; Jacobson M R; Lowhagen O; Rak S; Durham S R; Hamid Q
IL-13 mRNA and immunoreactivity in allergen-induced rhinitis: comparison with IL-4 expression and modulation by topical glucocorticoid therapy.
American journal of respiratory cell and molecular biology 1997;17(1):17-24.
1997: Sihra B S; Kon O M; Durham S R; Walker S; Barnes N C; Kay A B
Effect of cyclosporin A on the allergen-induced late asthmatic reaction.
Thorax 1997;52(5):447-52.
1997: Barata L T; Ying S; Grant J A; Humbert M; Barkans J; Meng Q; Durham S R; Kay A B
Allergen-induced recruitment of Fc epsilon RI+ eosinophils in human atopic skin.
European journal of immunology 1997;27(5):1236-41.
1997: Humbert M; Durham S R; Kimmitt P; Powell N; Assoufi B; Pfister R; Menz G; Kay A B; Corrigan C J
Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma.
The Journal of allergy and clinical immunology 1997;99(5):657-65.
1997: Ying S; Meng Q; Barata L T; Robinson D S; Durham S R; Kay A B
Associations between IL-13 and IL-4 (mRNA and protein), vascular cell adhesion molecule-1 expression, and the infiltration of eosinophils, macrophages, and T cells in allergen-induced late-phase cutaneous reactions in atopic subjects.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(10):5050-7.
1997: Grant J A; Humbert M; Taborda-Barata L; Sihra B S; Kon O M; Rajakulasingam K; Durham S R; Kay A B
High-affinity IgE receptor Fc epsilon RI expression in allergic reactions.
International archives of allergy and immunology 1997;113(1-3):376-8.
1997: Kay A B; Barata L; Meng Q; Durham S R; Ying S
Eosinophils and eosinophil-associated cytokines in allergic inflammation.
International archives of allergy and immunology 1997;113(1-3):196-9.
1997: Durham S R; Gould H J; Hamid Q A
Local IgE production in nasal allergy.
International archives of allergy and immunology 1997;113(1-3):128-30.
1997: Ying S; Humbert M; Barkans J; Corrigan C J; Pfister R; Menz G; Larché M; Robinson D S; Durham S R; Kay A B
Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(7):3539-44.
1997: Yasruel Z; Humbert M; Kotsimbos T C; Ploysongsang Y; Minshall E; Durham S R; Pfister R; Menz G; Tavernier J; Kay A B; Hamid Q
Membrane-bound and soluble alpha IL-5 receptor mRNA in the bronchial mucosa of atopic and nonatopic asthmatics.
American journal of respiratory and critical care medicine 1997;155(4):1413-8.
1997: Hamid Q A; Schotman E; Jacobson M R; Walker S M; Durham S R
Increases in IL-12 messenger RNA+ cells accompany inhibition of allergen-induced late skin responses after successful grass pollen immunotherapy.
The Journal of allergy and clinical immunology 1997;99(2):254-60.
1997: Rajakulasingam K; Hamid Q; O'Brien F; Shotman E; Jose P J; Williams T J; Jacobson M; Barkans J; Durham S R
RANTES in human allergen-induced rhinitis: cellular source and relation to tissue eosinophilia.
American journal of respiratory and critical care medicine 1997;155(2):696-703.
1997: Humbert M; Ying S; Corrigan C; Menz G; Barkans J; Pfister R; Meng Q; Van Damme J; Opdenakker G; Durham S R; Kay A B
Bronchial mucosal expression of the genes encoding chemokines RANTES and MCP-3 in symptomatic atopic and nonatopic asthmatics: relationship to the eosinophil-active cytokines interleukin (IL)-5, granulocyte macrophage-colony-stimulating factor, and IL-3.
American journal of respiratory cell and molecular biology 1997;16(1):1-8.
1996: Powell N; Humbert M; Durham S R; Assoufi B; Kay A B; Corrigan C J
Increased expression of mRNA encoding RANTES and MCP-3 in the bronchial mucosa in atopic asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1996;9(12):2454-60.
1996: Humbert M; Durham S R; Ying S; Kimmitt P; Barkans J; Assoufi B; Pfister R; Menz G; Robinson D S; Kay A B; Corrigan C J
IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: evidence against "intrinsic" asthma being a distinct immunopathologic entity.
American journal of respiratory and critical care medicine 1996;154(5):1497-504.
1996: Durham S R
Allergen avoidance measures. British Thoracic Society.
Respiratory medicine 1996;90(8):441-5.
1996: Bentley A M; Walker S; Hanotte F; De Vos C; Durham S R
A comparison of the effects of oral cetirizine and inhaled beclomethasone on early and late asthmatic responses to allergen and the associated increase in airways hyperresponsiveness.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1996;26(8):909-17.
1996: Humbert M; Robinson D S; Assoufi B; Kay A B; Durham S R
Safety of fibreoptic bronchoscopy in asthmatic and control subjects and effect on asthma control over two weeks.
Thorax 1996;51(7):664-9.
1996: Humbert M; Grant J A; Taborda-Barata L; Durham S R; Pfister R; Menz G; Barkans J; Ying S; Kay A B
High-affinity IgE receptor (FcepsilonRI)-bearing cells in bronchial biopsies from atopic and nonatopic asthma.
American journal of respiratory and critical care medicine 1996;153(6 Pt 1):1931-7.
1996: Durham S R; Ying S; Varney V A; Jacobson M R; Sudderick R M; Mackay I S; Kay A B; Hamid Q A
Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-gamma.
The Journal of allergy and clinical immunology 1996;97(6):1356-65.
1996: Bentley A M; Hamid Q; Robinson D S; Schotman E; Meng Q; Assoufi B; Kay A B; Durham S R
Prednisolone treatment in asthma. Reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa.
American journal of respiratory and critical care medicine 1996;153(2):551-6.
1996: Taborda-Barata L; Jacobson M; Walker S; Njuki F; Ying S; Randev P; Durham S R; Kay A B
Effect of cetirizine and prednisolone on cellular infiltration and cytokine mRNA expression during allergen-induced late cutaneous responses.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1996;26(1):68-78.
1996: Ying S; Meng Q; Taborda-Barata L; Corrigan C J; Barkans J; Assoufi B; Moqbel R; Durham S R; Kay A B
Human eosinophils express messenger RNA encoding RANTES and store and release biologically active RANTES protein.
European journal of immunology 1996;26(1):70-6.
1995: Robinson D S; Assoufi B; Durham S R; Kay A B
Eosinophil cationic protein (ECP) and eosinophil protein X (EPX) concentrations in serum and bronchial lavage fluid in asthma. Effect of prednisolone treatment.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1995;25(11):1118-27.
1995: Moqbel R; Ying S; Barkans J; Newman T M; Kimmitt P; Wakelin M; Taborda-Barata L; Meng Q; Corrigan C J; Durham S R; Kay A B
Identification of messenger RNA for IL-4 in human eosinophils with granule localization and release of the translated product.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(10):4939-47.
1995: Ying S; Durham S R; Corrigan C J; Hamid Q; Kay A B
Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects.
American journal of respiratory cell and molecular biology 1995;12(5):477-87.
1995: Durham S R; Kay A B; Hamid Q
Changes in allergic inflammation associated with successful immunotherapy.
International archives of allergy and immunology 1995;107(1-3):282-4.
1995: Kay A B; Ying S; Durham S R
Phenotype of cells positive for interleukin-4 and interleukin-5 mRNA in allergic tissue reactions.
International archives of allergy and immunology 1995;107(1-3):208-10.
1995: Walker S M; Varney V A; Gaga M; Jacobson M R; Durham S R
Grass pollen immunotherapy: efficacy and safety during a 4-year follow-up study.
Allergy 1995;50(5):405-13.
1995: Durham S R
New insights into the mechanisms of immunotherapy.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 1995;252 Suppl 1():S64-7.
1994: Tsicopoulos A; Hamid Q; Haczku A; Jacobson M R; Durham S R; North J; Barkans J; Corrigan C J; Meng Q; Moqbel R
Kinetics of cell infiltration and cytokine messenger RNA expression after intradermal challenge with allergen and tuberculin in the same atopic individuals.
The Journal of allergy and clinical immunology 1994;94(4):764-72.
1994: Rak S; Jacobson M R; Sudderick R M; Masuyama K; Juliusson S; Kay A B; Hamid Q; Löwhagen O; Durham S R
Influence of prolonged treatment with topical corticosteroid (fluticasone propionate) on early and late phase nasal responses and cellular infiltration in the nasal mucosa after allergen challenge.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1994;24(10):930-9.
1994: Ying S; Durham S R; Jacobson M R; Rak S; Masuyama K; Lowhagen O; Kay A B; Hamid Q A
T lymphocytes and mast cells express messenger RNA for interleukin-4 in the nasal mucosa in allergen-induced rhinitis.
Immunology 1994;82(2):200-6.
1994: Masuyama K; Jacobson M R; Rak S; Meng Q; Sudderick R M; Kay A B; Lowhagen O; Hamid Q; Durham S R
Topical glucocorticosteroid (fluticasone propionate) inhibits cells expressing cytokine mRNA for interleukin-4 in the nasal mucosa in allergen-induced rhinitis.
Immunology 1994;82(2):192-9.
1994: Varney V A; Cumberworth V; Sudderick R; Durham S R; Mackay I S
Rhinitis, sinusitis and the yellow nail syndrome: a review of symptoms and response to treatment in 17 patients.
Clinical otolaryngology and allied sciences 1994;19(3):237-40.
1993: Bentley A M; Durham S R; Robinson D S; Menz G; Storz C; Cromwell O; Kay A B; Wardlaw A J
Expression of endothelial and leukocyte adhesion molecules interacellular adhesion molecule-1, E-selectin, and vascular cell adhesion molecule-1 in the bronchial mucosa in steady-state and allergen-induced asthma.
The Journal of allergy and clinical immunology 1993;92(6):857-68.
1993: Ying S; Durham S R; Barkans J; Masuyama K; Jacobson M; Rak S; Löwhagen O; Moqbel R; Kay A B; Hamid Q A
T cells are the principal source of interleukin-5 mRNA in allergen-induced rhinitis.
American journal of respiratory cell and molecular biology 1993;9(4):356-60.
1993: Robinson D S; Ying S; Bentley A M; Meng Q; North J; Durham S R; Kay A B; Hamid Q
Relationships among numbers of bronchoalveolar lavage cells expressing messenger ribonucleic acid for cytokines, asthma symptoms, and airway methacholine responsiveness in atopic asthma.
The Journal of allergy and clinical immunology 1993;92(3):397-403.
1993: Robinson D; Hamid Q; Bentley A; Ying S; Kay A B; Durham S R
Activation of CD4+ T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma.
The Journal of allergy and clinical immunology 1993;92(2):313-24.
1993: Varney V A; Hamid Q A; Gaga M; Ying S; Jacobson M; Frew A J; Kay A B; Durham S R
Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses.
The Journal of clinical investigation 1993;92(2):644-51.
1993: Robinson D S; Durham S R; Kay A B
Cytokines. 3. Cytokines in asthma.
Thorax 1993;48(8):845-53.
1993: Corrigan C J; Haczku A; Gemou-Engesaeth V; Doi S; Kikuchi Y; Takatsu K; Durham S R; Kay A B
CD4 T-lymphocyte activation in asthma is accompanied by increased serum concentrations of interleukin-5. Effect of glucocorticoid therapy.
The American review of respiratory disease 1993;147(3):540-7.
1993: Robinson D S; Bentley A M; Hartnell A; Kay A B; Durham S R
Activated memory T helper cells in bronchoalveolar lavage fluid from patients with atopic asthma: relation to asthma symptoms, lung function, and bronchial responsiveness.
Thorax 1993;48(1):26-32.
1993: Bentley A M; Meng Q; Robinson D S; Hamid Q; Kay A B; Durham S R
Increases in activated T lymphocytes, eosinophils, and cytokine mRNA expression for interleukin-5 and granulocyte/macrophage colony-stimulating factor in bronchial biopsies after allergen inhalation challenge in atopic asthmatics.
American journal of respiratory cell and molecular biology 1993;8(1):35-42.
1993: Robinson D S; Hamid Q; Jacobson M; Ying S; Kay A B; Durham S R
Evidence for Th2-type T helper cell control of allergic disease in vivo.
Springer seminars in immunopathology 1993;15(1):17-27.
1992: Bentley A M; Menz G; Storz C; Robinson D S; Bradley B; Jeffery P K; Durham S R; Kay A B
Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma. Relationship to symptoms and bronchial responsiveness.
The American review of respiratory disease 1992;146(2):500-6.
1992: Varney V A; Jacobson M R; Sudderick R M; Robinson D S; Irani A M; Schwartz L B; Mackay I S; Kay A B; Durham S R
Immunohistology of the nasal mucosa following allergen-induced rhinitis. Identification of activated T lymphocytes, eosinophils, and neutrophils.
The American review of respiratory disease 1992;146(1):170-6.
1992: Durham S R; Ying S; Varney V A; Jacobson M R; Sudderick R M; Mackay I S; Kay A B; Hamid Q A
Cytokine messenger RNA expression for IL-3, IL-4, IL-5, and granulocyte/macrophage-colony-stimulating factor in the nasal mucosa after local allergen provocation: relationship to tissue eosinophilia.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(8):2390-4.
1992: Hamid Q; Barkans J; Robinson D S; Durham S R; Kay A B
Co-expression of CD25 and CD3 in atopic allergy and asthma.
Immunology 1992;75(4):659-63.
1992: Bentley A M; Jacobson M R; Cumberworth V; Barkans J R; Moqbel R; Schwartz L B; Irani A M; Kay A B; Durham S R
Immunohistology of the nasal mucosa in seasonal allergic rhinitis: increases in activated eosinophils and epithelial mast cells.
The Journal of allergy and clinical immunology 1992;89(4):877-83.
1992: Bentley A M; Maestrelli P; Saetta M; Fabbri L M; Robinson D S; Bradley B L; Jeffery P K; Durham S R; Kay A B
Activated T-lymphocytes and eosinophils in the bronchial mucosa in isocyanate-induced asthma.
The Journal of allergy and clinical immunology 1992;89(4):821-9.
1992: Tsicopoulos A; Hamid Q; Varney V; Ying S; Moqbel R; Durham S R; Kay A B
Preferential messenger RNA expression of Th1-type cells (IFN-gamma+, IL-2+) in classical delayed-type (tuberculin) hypersensitivity reactions in human skin.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(7):2058-61.
1992: Moqbel R; Barkans J; Bradley B L; Durham S R; Kay A B
Application of monoclonal antibodies against major basic protein (BMK-13) and eosinophil cationic protein (EG1 and EG2) for quantifying eosinophils in bronchial biopsies from atopic asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1992;22(2):265-73.
1992: Robinson D S; Hamid Q; Ying S; Tsicopoulos A; Barkans J; Bentley A M; Corrigan C; Durham S R; Kay A B
Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma.
The New England journal of medicine 1992;326(5):298-304.
1991: Ying S; Robinson D S; Varney V; Meng Q; Tsicopoulos A; Moqbel R; Durham S R; Kay A B; Hamid Q
TNF alpha mRNA expression in allergic inflammation.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1991;21(6):745-50.
1991: Bradley B L; Azzawi M; Jacobson M; Assoufi B; Collins J V; Irani A M; Schwartz L B; Durham S R; Jeffery P K; Kay A B
Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness.
The Journal of allergy and clinical immunology 1991;88(4):661-74.
1991: Hamid Q; Azzawi M; Ying S; Moqbel R; Wardlaw A J; Corrigan C J; Bradley B; Durham S R; Collins J V; Jeffery P K
Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.
The Journal of clinical investigation 1991;87(5):1541-6.
1991: Kay A B; Ying S; Varney V; Gaga M; Durham S R; Moqbel R; Wardlaw A J; Hamid Q
Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL-3), IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects.
The Journal of experimental medicine 1991;173(3):775-8.
1991: Varney V A; Gaga M; Frew A J; Aber V R; Kay A B; Durham S R
Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs.
BMJ (Clinical research ed.) 1991;302(6771):265-9.
1991: Durham S R; Varney V; Gaga M; Frew A J; Jacobson M; Kay A B
Immunotherapy and allergic inflammation.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1991;21 Suppl 1():206-10.
1991: Kay A B; Durham S R
T-lymphocytes, allergy and asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1991;21 Suppl 1():17-21.
1991: Hamid Q; Azzawi M; Ying S; Moqbel R; Wardlaw A J; Corrigan C J; Bradley B; Durham S R; Collins J V; Jeffery P K
Interleukin-5 mRNA in mucosal bronchial biopsies from asthmatic subjects.
International archives of allergy and applied immunology 1991;94(1-4):169-70.
1990: Durham S R
Late asthmatic responses.
Respiratory medicine 1990;84(4):263-8.
1989: Durham S R; Loegering D A; Dunnette S; Gleich G J; Kay A B
Blood eosinophils and eosinophil-derived proteins in allergic asthma.
The Journal of allergy and clinical immunology 1989;84(6 Pt 1):931-6.

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