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Michael Dustin
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27
Springer, Timothy
10
Shaw, Andrey
10
Sims, Tasha
8
Bromley, Shannon
8
Varma, Rajat
6
Allen, Paul
6
Campi, Gabriele
6
Groves, Jay
6
Sykulev, Yuri
6
Nussenzweig, Michel
5
Thomas, Kaye
5
Shakhar, Guy
5
Golan, David
5
Davis, Mark
5
Tseng, Su-Yi
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All Publications
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2009: Vasiliver-Shamis Gaia; Cho Michael W; Hioe Catarina E; Dustin Michael L
Human immunodeficiency virus type 1 envelope gp120-induced partial T-cell receptor signaling creates an F-actin-depleted zone in the virological synapse.
Journal of virology 2009;83(21):11341-55.
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2009: Beal Allison M; Anikeeva Nadia; Varma Rajat; Cameron Thomas O; Vasiliver-Shamis Gaia; Norris Philip J; Dustin Michael L; Sykulev Yuri
Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain.
Immunity 2009;31(4):632-42.
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2009: Dustin Michael L
Supported bilayers at the vanguard of immune cell activation studies.
Journal of structural biology 2009;168(1):152-60.
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2009: Srivastava Shekhar; Di Lie; Zhdanova Olga; Li Zhai; Vardhana Santosha; Wan Qi; Yan Ying; Varma Rajat; Backer Jonathan; Wulff Heike; Dustin Michael L; Skolnik Edward Y
The class II phosphatidylinositol 3 kinase C2beta is required for the activation of the K+ channel KCa3.1 and CD4 T-cells.
Molecular biology of the cell 2009;20(17):3783-91.
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2009: Chen Huan-Yuan; Fermin Agnes; Vardhana Santosh; Weng I-Chun; Lo Kin Fong Robin; Chang En-Yuh; Maverakis Emanual; Yang Ri-Yao; Hsu Daniel K; Dustin Michael L; Liu Fu-Tong
Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(34):14496-501.
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2009: Darrasse-Jèze Guillaume; Deroubaix Stephanie; Mouquet Hugo; Victora Gabriel D; Eisenreich Thomas; Yao Kai-hui; Masilamani Revati F; Dustin Michael L; Rudensky Alexander; Liu Kang; Nussenzweig Michel C
Feedback control of regulatory T cell homeostasis by dendritic cells in vivo.
The Journal of experimental medicine 2009;206(9):1853-62.
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2009: Liu Dongfang; Bryceson Yenan T; Meckel Tobias; Vasiliver-Shamis Gaia; Dustin Michael L; Long Eric O
Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses.
Immunity 2009;31(1):99-109.
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2009: Buonamici Silvia; Trimarchi Thomas; Ruocco Maria Grazia; Reavie Linsey; Cathelin Severine; Mar Brenton G; Klinakis Apostolos; Lukyanov Yevgeniy; Tseng Jen-Chieh; Sen Filiz; Gehrie Eric; Li Mengling; Newcomb Elizabeth; Zavadil Jiri; Meruelo Daniel; Lipp Martin; Ibrahim Sherif; Efstratiadis Argiris; Zagzag David; Bromberg Jonathan S; Dustin Michael L; Aifantis Iannis
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.
Nature 2009;459(7249):1000-4.
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2009: Kaizuka Yoshihisa; Douglass Adam D; Vardhana Santosh; Dustin Michael L; Vale Ronald D
The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells.
The Journal of cell biology 2009;185(3):521-34.
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2009: Ilani Tal; Vasiliver-Shamis Gaia; Vardhana Santosh; Bretscher Anthony; Dustin Michael L
T cell antigen receptor signaling and immunological synapse stability require myosin IIA.
Nature immunology 2009;10(5):531-9.
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2009: Dustin Michael L
The cellular context of T cell signaling.
Immunity 2009;30(4):482-92.
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2009: Kim Jiyun V; Kang Silvia S; Dustin Michael L; McGavern Dorian B
Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis.
Nature 2009;457(7226):191-5.
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2009: Dustin Michael L
Visualizing immune system complexity.
Science signaling 2009;2(66):mr4.
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2009: Velázquez Peter; Dustin Michael L; Nelson Peter J
Renal dendritic cells: an update.
Nephron. Experimental nephrology 2009;111(3):e67-71.
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2008: Milstein Oren; Tseng Su-Yi; Starr Toby; Llodra Jaime; Nans Andrea; Liu Mengling; Wild Martin K; van der Merwe P Anton; Stokes David L; Reisner Yair; Dustin Michael L
Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse.
The Journal of biological chemistry 2008;283(49):34414-22.
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2008: Yokosuka Tadashi; Kobayashi Wakana; Sakata-Sogawa Kumiko; Takamatsu Masako; Hashimoto-Tane Akiko; Dustin Michael L; Tokunaga Makio; Saito Takashi
Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation.
Immunity 2008;29(4):589-601.
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2008: Kim Natalie; Stiegler Amy L; Cameron Thomas O; Hallock Peter T; Gomez Andrea M; Huang Julie H; Hubbard Stevan R; Dustin Michael L; Burden Steven J
Lrp4 is a receptor for Agrin and forms a complex with MuSK.
Cell 2008;135(2):334-42.
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2008: Tseng Su-Yi; Waite Janelle C; Liu Mengling; Vardhana Santosha; Dustin Michael L
T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase C theta.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4852-63.
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2008: Beal Allison M; Anikeeva Nadia; Varma Rajat; Cameron Thomas O; Norris Philip J; Dustin Michael L; Sykulev Yuri
Protein kinase C theta regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4815-24.
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2008: Vasiliver-Shamis Gaia; Tuen Michael; Wu Teresa W; Starr Toby; Cameron Thomas O; Thomson Russell; Kaur Gurvinder; Liu Jianping; Visciano Maria Luisa; Li Hualin; Kumar Rajnish; Ansari Rais; Han Dong P; Cho Michael W; Dustin Michael L; Hioe Catarina E
Human immunodeficiency virus type 1 envelope gp120 induces a stop signal and virological synapse formation in noninfected CD4+ T cells.
Journal of virology 2008;82(19):9445-57.
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2008: Matsumura Satoko; Wang Baomei; Kawashima Noriko; Braunstein Steve; Badura Michelle; Cameron Thomas O; Babb James S; Schneider Robert J; Formenti Silvia C; Dustin Michael L; Demaria Sandra
Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(5):3099-107.
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2008: Kirchhof Mark G; Chau Luan A; Lemke Caitlin D; Vardhana Santosh; Darlington Peter J; Márquez Maria E; Taylor Roy; Rizkalla Kamilia; Blanca Isaac; Dustin Michael L; Madrenas Joaquín
Modulation of T cell activation by stomatin-like protein 2.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(3):1927-36.
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2008: Thauland Timothy J; Koguchi Yoshinobu; Wetzel Scott A; Dustin Michael L; Parker David C
Th1 and Th2 cells form morphologically distinct immunological synapses.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(1):393-9.
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2008: Wu Jianhua; Fang Ying; Zarnitsyna Veronika I; Tolentino Timothy P; Dustin Michael L; Zhu Cheng
A coupled diffusion-kinetics model for analysis of contact-area FRAP experiment.
Biophysical journal 2008;95(2):910-9.
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2008: Tolentino Timothy P; Wu Jianhua; Zarnitsyna Veronika I; Fang Ying; Dustin Michael L; Zhu Cheng
Measuring diffusion and binding kinetics by contact area FRAP.
Biophysical journal 2008;95(2):920-30.
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2008: Shen Keyue; Thomas V Kaye; Dustin Michael L; Kam Lance C
Micropatterning of costimulatory ligands enhances CD4+ T cell function.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(22):7791-6.
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2008: DeMond Andrew L; Mossman Kaspar D; Starr Toby; Dustin Michael L; Groves Jay T
T cell receptor microcluster transport through molecular mazes reveals mechanism of translocation.
Biophysical journal 2008;94(8):3286-92.
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2008: Dustin Michael L
Synaptic asymmetry to go.
Cell 2008;132(5):733-4.
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2008: Dustin Michael L
T-cell activation through immunological synapses and kinapses.
Immunological reviews 2008;221():77-89.
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2008: Velázquez Peter; Cameron Thomas O; Kinjo Yuki; Nagarajan Niranjana; Kronenberg Mitchell; Dustin Michael L
Cutting edge: activation by innate cytokines or microbial antigens can cause arrest of natural killer T cell patrolling of liver sinusoids.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(4):2024-8.
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2008: Dustin Michael L; Chakraborty Arup K
Tug of war at the exit door.
Immunity 2008;28(1):15-7.
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2008: Dustin Michael L
Visualization of cell-cell interaction contacts-synapses and kinapses.
Advances in experimental medicine and biology 2008;640():164-82.
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2008: Dustin Michael L
Hunter to gatherer and back: immunological synapses and kinapses as variations on the theme of amoeboid locomotion.
Annual review of cell and developmental biology 2008;24():577-96.
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2007: Kaizuka Yoshihisa; Douglass Adam D; Varma Rajat; Dustin Michael L; Vale Ronald D
Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(51):20296-301.
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2007: Velázquez Peter; Waite Janelle C; Dustin Michael L
Dynamics of host defense: the view at the front lines.
Nature immunology 2007;8(11):1153-7.
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2007: Dustin Michael L; Starr Toby; Coombs Daniel; Majeau Gerard R; Meier Werner; Hochman Paula S; Douglass Adam; Vale Ron; Goldstein Byron; Whitty Adrian
Quantification and modeling of tripartite CD2-, CD58FC chimera (alefacept)-, and CD16-mediated cell adhesion.
The Journal of biological chemistry 2007;282(48):34748-57.
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2007: Dustin Michael L
Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses.
Current opinion in cell biology 2007;19(5):529-33.
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2007: Skokos Dimitris; Shakhar Guy; Varma Rajat; Waite Janelle C; Cameron Thomas O; Lindquist Randall L; Schwickert Tanja; Nussenzweig Michel C; Dustin Michael L
Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes.
Nature immunology 2007;8(8):835-44.
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2007: Mor Adam; Dustin Michael L; Philips Mark R
Small GTPases and LFA-1 reciprocally modulate adhesion and signaling.
Immunological reviews 2007;218():114-25.
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2007: Huang Julie H; Cárdenas-Navia L Isabel; Caldwell Charles C; Plumb Troy J; Radu Caius G; Rocha Paulo N; Wilder Tuere; Bromberg Jonathan S; Cronstein Bruce N; Sitkovsky Michail; Dewhirst Mark W; Dustin Michael L
Requirements for T lymphocyte migration in explanted lymph nodes.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(12):7747-55.
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2007: Mor Adam; Campi Gabriele; Du Guangwei; Zheng Yang; Foster David A; Dustin Michael L; Philips Mark R
The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2.
Nature cell biology 2007;9(6):713-9.
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2007: Sims Tasha N; Soos Timothy J; Xenias Harry S; Dubin-Thaler Benjamin; Hofman Jake M; Waite Janelle C; Cameron Thomas O; Thomas V Kaye; Varma Rajat; Wiggins Chris H; Sheetz Michael P; Littman Dan R; Dustin Michael L
Opposing effects of PKCtheta and WASp on symmetry breaking and relocation of the immunological synapse.
Cell 2007;129(4):773-85.
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2007: Schwickert Tanja A; Lindquist Randall L; Shakhar Guy; Livshits Geulah; Skokos Dimitris; Kosco-Vilbois Marie H; Dustin Michael L; Nussenzweig Michel C
In vivo imaging of germinal centres reveals a dynamic open structure.
Nature 2007;446(7131):83-7.
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2007: Dustin Michael L; Starr Toby; Varma Rajat; Thomas V Kaye
Supported planar bilayers for study of the immunological synapse.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2007;Chapter 18():Unit 18.13.
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2007: Zhu De-Min; Dustin Michael L; Cairo Christopher W; Golan David E
Analysis of two-dimensional dissociation constant of laterally mobile cell adhesion molecules.
Biophysical journal 2007;92(3):1022-34.
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2007: Alon Ronen; Dustin Michael L
Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells.
Immunity 2007;26(1):17-27.
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2006: DeMond Andrew L; Starr Toby; Dustin Michael L; Groves Jay T
Control of antigen presentation with a photoreleasable agonist peptide.
Journal of the American Chemical Society 2006;128(48):15354-5.
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2006: Zhu De-Min; Dustin Michael L; Cairo Christopher W; Thatte Hemant S; Golan David E
Mechanisms of Cellular Avidity Regulation in CD2-CD58-Mediated T Cell Adhesion.
ACS chemical biology 2006;1(10):649-58.
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2006: Anikeeva Nadia; Lebedeva Tatiana; Clapp Aaron R; Goldman Ellen R; Dustin Michael L; Mattoussi Hedi; Sykulev Yuri
Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(45):16846-51.
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2006: Kim Jiyun V; Dustin Michael L
Innate response to focal necrotic injury inside the blood-brain barrier.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(8):5269-77.
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2006: Dustin Michael L
Immunology. When F-actin becomes too much of a good thing.
Science (New York, N.Y.) 2006;313(5788):767-8.
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2006: Dustin Michael L; Tseng Su-Yi; Varma Rajat; Campi Gabriele
T cell-dendritic cell immunological synapses.
Current opinion in immunology 2006;18(4):512-6.
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2006: Soos T J; Sims T N; Barisoni L; Lin K; Littman D R; Dustin M L; Nelson P J
CX3CR1+ interstitial dendritic cells form a contiguous network throughout the entire kidney.
Kidney international 2006;70(3):591-6.
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2006: Döbereiner Hans-Günther; Dubin-Thaler Benjamin J; Hofman Jake M; Xenias Harry S; Sims Tasha N; Giannone Grégory; Dustin Michael L; Wiggins Chris H; Sheetz Michael P
Lateral membrane waves constitute a universal dynamic pattern of motile cells.
Physical review letters 2006;97(3):038102.
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2006: Varma Rajat; Campi Gabriele; Yokosuka Tadashi; Saito Takashi; Dustin Michael L
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster.
Immunity 2006;25(1):117-27.
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2006: Germain Ronald N; Miller Mark J; Dustin Michael L; Nussenzweig Michel C
Dynamic imaging of the immune system: progress, pitfalls and promise.
Nature reviews. Immunology 2006;6(7):497-507.
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2006: Dustin Michael L; Zhu Cheng
T cells like a firm molecular handshake.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(12):4335-6.
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2006: Tadokoro Carlos E; Shakhar Guy; Shen Shiqian; Ding Yi; Lino Andreia C; Maraver Antonio; Lafaille Juan J; Dustin Michael L
Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo.
The Journal of experimental medicine 2006;203(3):505-11.
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2006: Dustin Michael L
Impact of the immunological synapse on T cell signaling.
Results and problems in cell differentiation 2006;43():175-98.
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2005: Tseng Su-Yi; Liu Mengling; Dustin Michael L
CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapse.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(12):7829-36.
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2005: Yokosuka Tadashi; Sakata-Sogawa Kumiko; Kobayashi Wakana; Hiroshima Michio; Hashimoto-Tane Akiko; Tokunaga Makio; Dustin Michael L; Saito Takashi
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.
Nature immunology 2005;6(12):1253-62.
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2005: Dustin Michael L
A dynamic view of the immunological synapse.
Seminars in immunology 2005;17(6):400-10.
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2005: Mossman Kaspar D; Campi Gabriele; Groves Jay T; Dustin Michael L
Altered TCR signaling from geometrically repatterned immunological synapses.
Science (New York, N.Y.) 2005;310(5751):1191-3.
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2005: Campi Gabriele; Varma Rajat; Dustin Michael L
Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling.
The Journal of experimental medicine 2005;202(8):1031-6.
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2005: Shakhar Guy; Lindquist Randall L; Skokos Dimitris; Dudziak Diana; Huang Julie H; Nussenzweig Michel C; Dustin Michael L
Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo.
Nature immunology 2005;6(7):707-14.
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2005: Davalos Dimitrios; Grutzendler Jaime; Yang Guang; Kim Jiyun V; Zuo Yi; Jung Steffen; Littman Dan R; Dustin Michael L; Gan Wen-Biao
ATP mediates rapid microglial response to local brain injury in vivo.
Nature neuroscience 2005;8(6):752-8.
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2005: Lebedeva Tatiana; Dustin Michael L; Sykulev Yuri
ICAM-1 co-stimulates target cells to facilitate antigen presentation.
Current opinion in immunology 2005;17(3):251-8.
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2005: Anikeeva Nadia; Somersalo Kristina; Sims Tasha N; Thomas V Kaye; Dustin Michael L; Sykulev Yuri
Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(18):6437-42.
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2005: Shao Jin-Yu; Yu Yan; Dustin Michael L
A model for CD2/CD58-mediated adhesion strengthening.
Annals of biomedical engineering 2005;33(4):483-93.
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2005: Geissmann Frederic; Cameron Thomas O; Sidobre Stephane; Manlongat Natasha; Kronenberg Mitchell; Briskin Michael J; Dustin Michael L; Littman Dan R
Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids.
PLoS biology 2005;3(4):e113.
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2005: Heissmeyer Vigo; Macián Fernando; Varma Rajat; Im Sin-Hyeog; García-Cozar Francisco; Horton Heidi F; Byrne Michael C; Feske Stefan; Venuprasad K; Gu Hua; Liu Yun-Cai; Dustin Michael L; Rao Anjana
A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling.
Novartis Foundation symposium 2005;267():165-74; discussion 174-9.
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2004: Lindquist Randall L; Shakhar Guy; Dudziak Diana; Wardemann Hedda; Eisenreich Thomas; Dustin Michael L; Nussenzweig Michel C
Visualizing dendritic cell networks in vivo.
Nature immunology 2004;5(12):1243-50.
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2004: Sims Tasha N; Dustin Michael L
A polarizing situation.
Nature immunology 2004;5(10):1012-3.
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2004: Dustin Michael L
Stop and go traffic to tune T cell responses.
Immunity 2004;21(3):305-14.
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2004: Sumen Cenk; Dustin Michael L; Davis Mark M
T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation.
The Journal of cell biology 2004;166(4):579-90.
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2004: Davis Daniel M; Dustin Michael L
What is the importance of the immunological synapse?
Trends in immunology 2004;25(6):323-7.
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2004: Carrasco Yolanda R; Fleire Sebastian J; Cameron Thomas; Dustin Michael L; Batista Facundo D
LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation.
Immunity 2004;20(5):589-99.
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2004: Dustin Michael
A supercode for inflammation.
Immunity 2004;20(4):361-2.
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2004: Dustin Michael L; Bivona Trever G; Philips Mark R
Membranes as messengers in T cell adhesion signaling.
Nature immunology 2004;5(4):363-72.
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2004: Heissmeyer Vigo; Macián Fernando; Im Sin-Hyeog; Varma Rajat; Feske Stefan; Venuprasad K; Gu Hua; Liu Yun-Cai; Dustin Michael L; Rao Anjana
Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins.
Nature immunology 2004;5(3):255-65.
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2004: Somersalo Kristina; Anikeeva Nadja; Sims Tasha N; Thomas V Kaye; Strong Roland K; Spies Thomas; Lebedeva Tatiana; Sykulev Yuri; Dustin Michael L
Cytotoxic T lymphocytes form an antigen-independent ring junction.
The Journal of clinical investigation 2004;113(1):49-57.
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2003: Lee Kyeong-Hee; Dinner Aaron R; Tu Chun; Campi Gabriele; Raychaudhuri Subhadip; Varma Rajat; Sims Tasha N; Burack W Richard; Wu Hui; Wang Julia; Kanagawa Osami; Markiewicz Mary; Allen Paul M; Dustin Michael L; Chakraborty Arup K; Shaw Andrey S
The immunological synapse balances T cell receptor signaling and degradation.
Science (New York, N.Y.) 2003;302(5648):1218-22.
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2003: Chakraborty Arup K; Dustin Michael L; Shaw Andrey S
In silico models for cellular and molecular immunology: successes, promises and challenges.
Nature immunology 2003;4(10):933-6.
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2003: Groves Jay T; Dustin Michael L
Supported planar bilayers in studies on immune cell adhesion and communication.
Journal of immunological methods 2003;278(1-2):19-32.
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2003: Dustin Michael L
Coordination of T cell activation and migration through formation of the immunological synapse.
Annals of the New York Academy of Sciences 2003;987():51-9.
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2003: Dustin Michael
Viral spread through protoplasmic kiss.
Nature cell biology 2003;5(4):271-2.
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2003: Dustin Michael L
In vivo imaging approaches in animal models of rheumatoid arthritis.
Arthritis research & therapy 2003;5(4):165-71.
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2002: Dustin Michael L; Colman David R
Neural and immunological synaptic relations.
Science (New York, N.Y.) 2002;298(5594):785-9.
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2002: Lee Sung-Joo E; Hori Yuko; Groves Jay T; Dustin Michael L; Chakraborty Arup K
The synapse assembly model.
Trends in immunology 2002;23(10):500-2.
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2002: Lee Sung-Joo E; Hori Yuko; Groves Jay T; Dustin Michael L; Chakraborty Arup K
Correlation of a dynamic model for immunological synapse formation with effector functions: two pathways to synapse formation.
Trends in immunology 2002;23(10):492-9.
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2002: Tseng Su-Yi; Dustin Michael L
T-cell activation: a multidimensional signaling network.
Current opinion in cell biology 2002;14(5):575-80.
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2002: Burack W Richard; Lee Kyeong-Hee; Holdorf Amy D; Dustin Michael L; Shaw Andrey S
Cutting edge: quantitative imaging of raft accumulation in the immunological synapse.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):2837-41.
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2002: Sims Tasha N; Dustin Michael L
The immunological synapse: integrins take the stage.
Immunological reviews 2002;186():100-17.
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2002: Dustin Michael L
Shmoos, rafts, and uropods- the many facets of cell polarity.
Cell 2002;110(1):13-8.
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2002: Bromley Shannon K; Dustin Michael L
Stimulation of naïve T-cell adhesion and immunological synapse formation by chemokine-dependent and -independent mechanisms.
Immunology 2002;106(3):289-98.
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2002: Hailman Eric; Burack W Richard; Shaw Andrey S; Dustin Michael L; Allen Paul M
Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation.
Immunity 2002;16(6):839-48.
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2002: Savage Nigel D L; Kimzey Stephanie L; Bromley Shannon K; Johnson Kenneth G; Dustin Michael L; Green Jonathan M
Polar redistribution of the sialoglycoprotein CD43: implications for T cell function.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):3740-6.
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2002: Antón Inés M; de la Fuente Miguel A; Sims Tasha N; Freeman Sheryl; Ramesh Narayanaswamy; Hartwig John H; Dustin Michael L; Geha Raif S
WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation.
Immunity 2002;16(2):193-204.
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2002: Lee Kyeong-Hee; Holdorf Amy D; Dustin Michael L; Chan Andrew C; Allen Paul M; Shaw Andrey S
T cell receptor signaling precedes immunological synapse formation.
Science (New York, N.Y.) 2002;295(5559):1539-42.
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2002: Dustin Michael L
Membrane domains and the immunological synapse: keeping T cells resting and ready.
The Journal of clinical investigation 2002;109(2):155-60.
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2002: Wülfing Christoph; Sumen Cenk; Sjaastad Michael D; Wu Lawren C; Dustin Michael L; Davis Mark M
Costimulation and endogenous MHC ligands contribute to T cell recognition.
Nature immunology 2002;3(1):42-7.
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2002: Dustin Michael L
Regulation of T cell migration through formation of immunological synapses: the stop signal hypothesis.
Advances in experimental medicine and biology 2002;512():191-201.
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2002: Dustin Michael L
The immunological synapse.
Arthritis research 2002;4 Suppl 3():S119-25.
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2001: Bromley S K; Iaboni A; Davis S J; Whitty A; Green J M; Shaw A S; Weiss A; Dustin M L
The immunological synapse and CD28-CD80 interactions.
Nature immunology 2001;2(12):1159-66.
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2001: Dustin M L
Role of adhesion molecules in activation signaling in T lymphocytes.
Journal of clinical immunology 2001;21(4):258-63.
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2001: Dustin M L; de Fougerolles A R
Reprogramming T cells: the role of extracellular matrix in coordination of T cell activation and migration.
Current opinion in immunology 2001;13(3):286-90.
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2001: Dustin M L; Bromley S K; Davis M M; Zhu C
Identification of self through two-dimensional chemistry and synapses.
Annual review of cell and developmental biology 2001;17():133-57.
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2001: Bromley S K; Burack W R; Johnson K G; Somersalo K; Sims T N; Sumen C; Davis M M; Shaw A S; Allen P M; Dustin M L
The immunological synapse.
Annual review of immunology 2001;19():375-96.
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2000: Dustin M L; Chan A C
Signaling takes shape in the immune system.
Cell 2000;103(2):283-94.
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2000: Johnson K G; Bromley S K; Dustin M L; Thomas M L
A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(18):10138-43.
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2000: Dustin M L; Cooper J A
The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.
Nature immunology 2000;1(1):23-9.
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2000: Bromley S K; Peterson D A; Gunn M D; Dustin M L
Cutting edge: hierarchy of chemokine receptor and TCR signals regulating T cell migration and proliferation.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):15-9.
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1999: Shih N Y; Li J; Karpitskii V; Nguyen A; Dustin M L; Kanagawa O; Miner J H; Shaw A S
Congenital nephrotic syndrome in mice lacking CD2-associated protein.
Science (New York, N.Y.) 1999;286(5438):312-5.
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1999: Grakoui A; Bromley S K; Sumen C; Davis M M; Shaw A S; Allen P M; Dustin M L
The immunological synapse: a molecular machine controlling T cell activation.
Science (New York, N.Y.) 1999;285(5425):221-7.
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1999: Davis M M; Wülfing C; Krummel M F; Savage P A; Xu J; Sumen C; Dustin M L; Chien Y H
Visualizing T-cell recognition.
Cold Spring Harbor symposia on quantitative biology 1999;64():243-51.
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1998: Dustin M L; Olszowy M W; Holdorf A D; Li J; Bromley S; Desai N; Widder P; Rosenberger F; van der Merwe P A; Allen P M; Shaw A S
A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts.
Cell 1998;94(5):667-77.
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1998: Dustin M L
Making a little affinity go a long way: a topological view of LFA-1 regulation.
Cell adhesion and communication 1998;6(2-3):255-62.
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1997: Dustin M L; Golan D E; Zhu D M; Miller J M; Meier W; Davies E A; van der Merwe P A
Low affinity interaction of human or rat T cell adhesion molecule CD2 with its ligand aligns adhering membranes to achieve high physiological affinity.
The Journal of biological chemistry 1997;272(49):30889-98.
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1997: Ganpule G; Knorr R; Miller J M; Carron C P; Dustin M L
Low affinity of cell surface lymphocyte function-associated antigen-1 (LFA-1) generates selectivity for cell-cell interactions.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(6):2685-92.
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1997: Knorr R; Dustin M L
The lymphocyte function-associated antigen 1 I domain is a transient binding module for intercellular adhesion molecule (ICAM)-1 and ICAM-3 in hydrodynamic flow.
The Journal of experimental medicine 1997;186(5):719-30.
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1997: Dustin M L
Adhesive bond dynamics in contacts between T lymphocytes and glass-supported planar bilayers reconstituted with the immunoglobulin-related adhesion molecule CD58.
The Journal of biological chemistry 1997;272(25):15782-8.
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1997: Shaw A S; Dustin M L
Making the T cell receptor go the distance: a topological view of T cell activation.
Immunity 1997;6(4):361-9.
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1997: Dustin M L; Bromley S K; Kan Z; Peterson D A; Unanue E R
Antigen receptor engagement delivers a stop signal to migrating T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3909-13.
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1996: Dustin M L; Miller J M; Ranganath S; Vignali D A; Viner N J; Nelson C A; Unanue E R
TCR-mediated adhesion of T cell hybridomas to planar bilayers containing purified MHC class II/peptide complexes and receptor shedding during detachment.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(5):2014-21.
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1996: Dustin M L; Ferguson L M; Chan P Y; Springer T A; Golan D E
Visualization of CD2 interaction with LFA-3 and determination of the two-dimensional dissociation constant for adhesion receptors in a contact area.
The Journal of cell biology 1996;132(3):465-74.
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1995: Miller J; Knorr R; Ferrone M; Houdei R; Carron C P; Dustin M L
Intercellular adhesion molecule-1 dimerization and its consequences for adhesion mediated by lymphocyte function associated-1.
The Journal of experimental medicine 1995;182(5):1231-41.
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1995: Meyer D M; Dustin M L; Carron C P
Characterization of intercellular adhesion molecule-1 ectodomain (sICAM-1) as an inhibitor of lymphocyte function-associated molecule-1 interaction with ICAM-1.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(7):3578-84.
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1992: Tözeren A; Mackie L H; Lawrence M B; Chan P Y; Dustin M L; Springer T A
Micromanipulation of adhesion of phorbol 12-myristate-13-acetate-stimulated T lymphocytes to planar membranes containing intercellular adhesion molecule-1.
Biophysical journal 1992;63(1):247-58.
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1992: Dustin M L; Carpen O; Springer T A
Regulation of locomotion and cell-cell contact area by the LFA-1 and ICAM-1 adhesion receptors.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(9):2654-63.
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1992: Tözeren A; Sung K L; Sung L A; Dustin M L; Chan P Y; Springer T A; Chien S
Micromanipulation of adhesion of a Jurkat cell to a planar bilayer membrane containing lymphocyte function-associated antigen 3 molecules.
The Journal of cell biology 1992;116(4):997-1006.
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1991: Carpén O; Dustin M L; Springer T A; Swafford J A; Beckett L A; Caulfield J P
Motility and ultrastructure of large granular lymphocytes on lipid bilayers reconstituted with adhesion receptors LFA-1, ICAM-1, and two isoforms of LFA-3.
The Journal of cell biology 1991;115(3):861-71.
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1991: Chan P Y; Lawrence M B; Dustin M L; Ferguson L M; Golan D E; Springer T A
Influence of receptor lateral mobility on adhesion strengthening between membranes containing LFA-3 and CD2.
The Journal of cell biology 1991;115(1):245-55.
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1991: Dustin M L; Springer T A
Role of lymphocyte adhesion receptors in transient interactions and cell locomotion.
Annual review of immunology 1991;9():27-66.
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1990: Johnston S C; Dustin M L; Hibbs M L; Springer T A
On the species specificity of the interaction of LFA-1 with intercellular adhesion molecules.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(4):1181-7.
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1990: Staunton D E; Dustin M L; Erickson H P; Springer T A
The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus.
Cell 1990;61(2):243-54.
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1989: Dustin M L; Springer T A
T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1.
Nature 1989;341(6243):619-24.
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1989: Staunton D E; Dustin M L; Springer T A
Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1.
Nature 1989;339(6219):61-4.
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1989: Staunton D E; Fisher R C; LeBeau M M; Lawrence J B; Barton D E; Francke U; Dustin M; Thorley-Lawson D A
Blast-1 possesses a glycosyl-phosphatidylinositol (GPI) membrane anchor, is related to LFA-3 and OX-45, and maps to chromosome 1q21-23.
The Journal of experimental medicine 1989;169(3):1087-99.
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1989: Dustin M L; Olive D; Springer T A
Correlation of CD2 binding and functional properties of multimeric and monomeric lymphocyte function-associated antigen 3.
The Journal of experimental medicine 1989;169(2):503-17.
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1989: Dustin M L; Garcia-Aguilar J; Hibbs M L; Larson R S; Stacker S A; Staunton D E; Wardlaw A J; Springer T A
Structure and regulation of the leukocyte adhesion receptor LFA-1 and its counterreceptors, ICAM-1 and ICAM-2.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 2():753-65.
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1989: Kishimoto T K; Larson R S; Corbi A L; Dustin M L; Staunton D E; Springer T A
The leukocyte integrins.
Advances in immunology 1989;46():149-82.
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1988: Denning S M; Dustin M L; Springer T A; Singer K H; Haynes B F
Purified lymphocyte function-associated antigen-3 (LFA-3) activates human thymocytes via the CD2 pathway.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(9):2980-5.
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1988: Dustin M L; Springer T A
Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.
The Journal of cell biology 1988;107(1):321-31.
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1988: Dustin M L; Singer K H; Tuck D T; Springer T A
Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1).
The Journal of experimental medicine 1988;167(4):1323-40.
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1988: Makgoba M W; Sanders M E; Ginther Luce G E; Gugel E A; Dustin M L; Springer T A; Shaw S
Functional evidence that intercellular adhesion molecule-1 (ICAM-1) is a ligand for LFA-1-dependent adhesion in T cell-mediated cytotoxicity.
European journal of immunology 1988;18(4):637-40.
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1988: Staunton D E; Marlin S D; Stratowa C; Dustin M L; Springer T A
Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families.
Cell 1988;52(6):925-33.
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1988: Makgoba M W; Sanders M E; Ginther Luce G E; Dustin M L; Springer T A; Clark E A; Mannoni P; Shaw S
ICAM-1 a ligand for LFA-1-dependent adhesion of B, T and myeloid cells.
Nature 1988;331(6151):86-8.
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1987: Dustin M L; Selvaraj P; Mattaliano R J; Springer T A
Anchoring mechanisms for LFA-3 cell adhesion glycoprotein at membrane surface.
Nature 1987;329(6142):846-8.
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1987: Wallner B P; Frey A Z; Tizard R; Mattaliano R J; Hession C; Sanders M E; Dustin M L; Springer T A
Primary structure of lymphocyte function-associated antigen 3 (LFA-3). The ligand of the T lymphocyte CD2 glycoprotein.
The Journal of experimental medicine 1987;166(4):923-32.
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1987: Selvaraj P; Dustin M L; Silber R; Low M G; Springer T A
Deficiency of lymphocyte function-associated antigen 3 (LFA-3) in paroxysmal nocturnal hemoglobinuria. Functional correlates and evidence for a phosphatidylinositol membrane anchor.
The Journal of experimental medicine 1987;166(4):1011-25.
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1987: Selvaraj P; Dustin M L; Mitnacht R; Hünig T; Springer T A; Plunkett M L
Rosetting of human T lymphocytes with sheep and human erythrocytes. Comparison of human and sheep ligand binding using purified E receptor.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(8):2690-5.
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1987: Dustin M L; Sanders M E; Shaw S; Springer T A
Purified lymphocyte function-associated antigen 3 binds to CD2 and mediates T lymphocyte adhesion.
The Journal of experimental medicine 1987;165(3):677-92.
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1987: Plunkett M L; Sanders M E; Selvaraj P; Dustin M L; Springer T A
Rosetting of activated human T lymphocytes with autologous erythrocytes. Definition of the receptor and ligand molecules as CD2 and lymphocyte function-associated antigen 3 (LFA-3).
The Journal of experimental medicine 1987;165(3):664-76.
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1987: Selvaraj P; Plunkett M L; Dustin M; Sanders M E; Shaw S; Springer T A
The T lymphocyte glycoprotein CD2 binds the cell surface ligand LFA-3.
Nature 1987;326(6111):400-3.
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1987: Springer T A; Dustin M L; Kishimoto T K; Marlin S D
The lymphocyte function-associated LFA-1, CD2, and LFA-3 molecules: cell adhesion receptors of the immune system.
Annual review of immunology 1987;5():223-52.
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1986: Rothlein R; Dustin M L; Marlin S D; Springer T A
A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(4):1270-4.
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