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Michael Duszenko

Research Profile

Concepts & Ideas

Chemicals & Drugs

Living Beings

Mouse

Physiology

Disorders

Trypanosomiasis, African

Genes & Molecular Sequences

Amino Acid Sequences

Procedures

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Publications

TOP 3
Tomoaki Bessho; Appolinaire Djikeng; Michael Duszenko; Takashi Inui; Toshihide Kusumoto; Samuel K Martin; Shoko Morii; Shigenori Nishimura; Masanori Noda; Takahiro Shinohara; Satoshi Shuto; Susumu Uchiyama; Kilunga B Kubata
Characterization of the novel Trypanosoma brucei inosine 5'-monophosphate dehydrogenase.
Mehrdad Ghashghaeinia; Martin Köberle; Florian Lang; Mohammad Saki; Yuliya Skabytska; Mahmoud Toulany; Thomas Wieder; Ahmad Akel; Tilo Biedermann; Judith C A Cluitmans; Peter Dreischer; Michael Duszenko; Giel J C G M Bosman
The impact of erythrocyte age on eryptosis.
Hartwig Wolburg; Sven Acker; Claudia Frey; Bruno Kilunga Kubata; Michael Lazarus; Monika Meinert; Stefan Mogk; Caroline Schönfeld; Yoshihiro Urade; Michael Duszenko
Late stage infection in sleeping sickness.

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All Publications

2013: Tomoaki Bessho; Appolinaire Djikeng; Michael Duszenko; Takashi Inui; Toshihide Kusumoto; Samuel K Martin; Shoko Morii; Shigenori Nishimura; Masanori Noda; Takahiro Shinohara; Satoshi Shuto; Susumu Uchiyama; Kilunga B Kubata
Characterization of the novel Trypanosoma brucei inosine 5'-monophosphate dehydrogenase.
Parasitology 2013;140(6):735-45.
2012: Mehrdad Ghashghaeinia; Martin Köberle; Florian Lang; Mohammad Saki; Yuliya Skabytska; Mahmoud Toulany; Thomas Wieder; Ahmad Akel; Tilo Biedermann; Judith C A Cluitmans; Peter Dreischer; Michael Duszenko; Giel J C G M Bosman
The impact of erythrocyte age on eryptosis.
British journal of haematology 2012;157(5):606-14.
2012: Hartwig Wolburg; Sven Acker; Claudia Frey; Bruno Kilunga Kubata; Michael Lazarus; Monika Meinert; Stefan Mogk; Caroline Schönfeld; Yoshihiro Urade; Michael Duszenko
Late stage infection in sleeping sickness.
PloS one 2012;7(3):e34304.
2011: Nicole Heise; Ekaterina Shumilina; Meerim K Nurbaeva; Evi Schmid; Kalina Szteyn; Wenting Yang; Nguyen Thi Xuan; Kan Wang; Irina M Zemtsova; Michael Duszenko; Florian Lang
Effect of dexamethasone on Na+/Ca2+ exchanger in dendritic cells.
American journal of physiology. Cell physiology 2011;300(6):C1306-13.
2011: Michael Duszenko; Michael L Ginger; Ana Brennand; Melisa Gualdrón-López; María Isabel Colombo; Graham H Coombs; Isabelle Coppens; Bamini Jayabalasingham; Gordon Langsley; Solange Lisboa de Castro; Rubem Menna-Barreto; Jeremy C Mottram; Miguel Navarro; Daniel J Rigden; Patricia S Romano; Veronika Stoka; Boris Turk; Paul A M Michels
Autophagy in protists.
Autophagy 2011;7(2):127-58.
2011: Björn Bassarak; Nestor L Uzcátegui; Caroline Schönfeld; Michael Duszenko
Functional characterization of three aquaglyceroporins from Trypanosoma brucei in osmoregulation and glycerol transport.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2011;27(3-4):411-20.
2010: Ger van Zandbergen; Carsten G K Lüder; Volker Heussler; Michael Duszenko
Programmed cell death in unicellular parasites: a prerequisite for sustained infection?
Trends in parasitology 2010;26(10):477-83.
2010: Despina Smirlis; Michael Duszenko; Antonio Jiménez Ruiz; Effie Scoulica; Patrick Bastien; Nicolas Fasel; Ketty Soteriadou
Targeting essential pathways in trypanosomatids gives insights into protozoan mechanisms of cell death.
Parasites & vectors 2010;3():107.
2009: Rudolf Koopmann; Khalid Muhammad; Markus Perbandt; Christian Betzel; Michael Duszenko
Trypanosoma brucei ATG8: structural insights into autophagic-like mechanisms in protozoa.
Autophagy 2009;5(8):1085-91.
2009: Ulrike Henrion; Nathalie Strutz-Seebohm; Michael Duszenko; Florian Lang; Guiscard Seebohm
Long QT syndrome-associated mutations in the voltage sensor of I(Ks) channels.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009;24(1-2):11-6.
2008: Nicole Matzner; Irina M Zemtsova; Thi Xuan Nguyen; Michael Duszenko; Ekaterina Shumilina; Florian Lang
Ion channels modulating mouse dendritic cell functions.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(10):6803-9.
2008: Viola Denninger; Rudolf Koopmann; Khalid Muhammad; Torsten Barth; Bjoern Bassarak; Caroline Schönfeld; Bruno Kubata Kilunga; Michael Duszenko
Kinetoplastida: model organisms for simple autophagic pathways?
Methods in enzymology 2008;451():373-408.
2007: Néstor L Uzcátegui; Viola Denninger; Patrick Merkel; Caroline Schoenfeld; Katherine Figarella; Michael Duszenko
Dihydroxyacetone induced autophagy in African trypanosomes.
Autophagy 2007;3(6):626-9.
2007: Néstor L Uzcátegui; Didac Carmona-Gutiérrez; Viola Denninger; Caroline Schoenfeld; Florian Lang; Katherine Figarella; Michael Duszenko
Antiproliferative effect of dihydroxyacetone on Trypanosoma brucei bloodstream forms: cell cycle progression, subcellular alterations, and cell death.
Antimicrobial agents and chemotherapy 2007;51(11):3960-8.
2007: Patrick Merkel; Alexander Beck; Khalid Muhammad; Syed Abid Ali; Caroline Schönfeld; Wolfgang Voelter; Michael Duszenko
Spermine isolated and identified as the major trypanocidal compound from the snake venom of Eristocophis macmahoni causes autophagy in Trypanosoma brucei.
Toxicon : official journal of the International Society on Toxinology 2007;50(4):457-69.
2007: Bruno Kilunga Kubata; Michael Duszenko; K Samuel Martin; Yoshihiro Urade
Molecular basis for prostaglandin production in hosts and parasites.
Trends in parasitology 2007;23(7):325-31.
2007: Viola Denninger; Katherine Figarella; Caroline Schönfeld; Stefanie Brems; Christian Busold; Florian Lang; Jörg D Hoheisel; Michael Duszenko
Troglitazone induces differentiation in Trypanosoma brucei.
Experimental cell research 2007;313(9):1805-19.
2006: Michael Duszenko; Katherine Figarella; Ewan Thomas Macleod; Susan C Welburn
Death of a trypanosome: a selfish altruism.
Trends in parasitology 2006;22(11):536-42.
2006: Katherine Figarella; Nestor L Uzcategui; Alexander Beck; Caroline Schoenfeld; Bruno Kilunga Kubata; Florian Lang; Michael Duszenko
Prostaglandin-induced programmed cell death in Trypanosoma brucei involves oxidative stress.
Cell death and differentiation 2006;13(10):1802-14.
2006: Thomas Zeuthen; Binghua Wu; Slavica Pavlovic-Djuranovic; Lars M Holm; Nestor L Uzcategui; Michael Duszenko; Jürgen Kun; Joachim E Schultz; Eric Beitz
Ammonia permeability of the aquaglyceroporins from Plasmodium falciparum, Toxoplasma gondii and Trypansoma brucei.
Molecular microbiology 2006;61(6):1598-608.
2006: Dan Yang Huang; Krishna M Boini; Philipp A Lang; Florian Grahammer; Michael Duszenko; Birgit Heller-Stilb; Ulrich Warskulat; Dieter Häussinger; Florian Lang; Volker Vallon
Impaired ability to increase water excretion in mice lacking the taurine transporter gene TAUT.
Pflügers Archiv : European journal of physiology 2006;451(5):668-77.
2006: Syed Abid Ali; Bingxian Wang; Mehtab Alam; Alexander Beck; Stanka Stoeva; Wolfgang Voelter; Atiya Abbasi; Michael Duszenko
Structure-activity relationship of an alpha-toxin Bs-Tx28 from scorpion (Buthus sindicus) venom suggests a new alpha-toxin subfamily.
Archives of biochemistry and biophysics 2006;445(1):81-94.
2005: Holger K Eltzschig; Parween Abdulla; Edgar Hoffman; Kathryn E Hamilton; Dionne Daniels; Caroline Schönfeld; Michaela Löffler; German Reyes; Michael Duszenko; Jorn Karhausen; Andreas Robinson; Karen A Westerman; Imogen R Coe; Sean P Colgan
HIF-1-dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia.
The Journal of experimental medicine 2005;202(11):1493-505.
2005: Elena Melnikow; Saffron Dornan; Carole Sargent; Michael Duszenko; Gary Evans; Nikolas Gunkel; Paul M Selzer; Heinz J Ullrich
Microarray analysis of Haemophilus parasuis gene expression under in vitro growth conditions mimicking the in vivo environment.
Veterinary microbiology 2005;110(3-4):255-63.
2005: Syed Tasadaque Ali Shah; Patrick Merkel; Hubert Ragge; Michael Duszenko; Jörg Rademann; Wolfgang Voelter
Stereospecific synthesis of chiral 2,3-dihydro-1,4-benzodithiine and methyl-2,3-dihydro-1,4-benzodithiine derivatives and their toxic effects on Trypanosoma brucei.
Chembiochem : a European journal of chemical biology 2005;6(8):1438-41.
2005: Kubata Bruno Kilunga; Tsuyoshi Inoue; Yousuke Okano; Zakayi Kabututu; Samuel K Martin; Michael Lazarus; Michael Duszenko; Yuichi Sumii; Yukiko Kusakari; Hiroyoshi Matsumura; Yasushi Kai; Shigeru Sugiyama; Kouji Inaka; Takashi Inui; Yoshihiro Urade
Structural and mutational analysis of Trypanosoma brucei prostaglandin H2 reductase provides insight into the catalytic mechanism of aldo-ketoreductases.
The Journal of biological chemistry 2005;280(28):26371-82.
2005: Björn Friedrich; Dorothea Alexander; Wilhelm Karl Aicher; Michael Duszenko; Thomas P Schaub; Jutta Passlick-Deetjen; Siegfried Waldegger; Sabine Wolf; Teut Risler; Florian Lang
Influence of standard haemodialysis treatment on transcription of human serum- and glucocorticoid-inducible kinase SGK1 and taurine transporter TAUT in blood leukocytes.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2005;20(4):768-74.
2005: Katherine Figarella; Marc Rawer; Nestor L Uzcategui; Bruno Kilunga Kubata; Kirsten Lauber; Frank Madeo; Sebastian Wesselborg; Michael Duszenko
Prostaglandin D2 induces programmed cell death in Trypanosoma brucei bloodstream form.
Cell death and differentiation 2005;12(4):335-46.
2005: Bruno Kilunga Kubata; Kisaburo Nagamune; Nobutoshi Murakami; Patrick Merkel; Zakayi Kabututu; Samuel K Martin; Taba M Kalulu; M D Mostaqul Huq; Haq Mustakuk; Mitsuru Yoshida; Mayumi Ohnishi-Kameyama; Taroh Kinoshita; Michael Duszenko; Yoshihiro Urade
Kola acuminata proanthocyanidins: a class of anti-trypanosomal compounds effective against Trypanosoma brucei.
International journal for parasitology 2005;35(1):91-103.
2004: Nestor L Uzcategui; Alexander Szallies; Slavica Pavlovic-Djuranovic; Monica Palmada; Katherine Figarella; Christoph Boehmer; Florian Lang; Eric Beitz; Michael Duszenko
Cloning, heterologous expression, and characterization of three aquaglyceroporins from Trypanosoma brucei.
The Journal of biological chemistry 2004;279(41):42669-76.
2003: Zakayi Kabututu; Samuel K Martin; Tomoyoshi Nozaki; Shin-ichiro Kawazu; Tetsuya Okada; Craig Joe Munday; Michael Duszenko; Michael Lazarus; Lucy W Thuita; Yoshihiro Urade; Bruno Kilunga Kubata
Prostaglandin production from arachidonic acid and evidence for a 9,11-endoperoxide prostaglandin H2 reductase in Leishmania.
International journal for parasitology 2003;33(2):221-8.
2003: Philipp A Lang; Ulrich Warskulat; Birgit Heller-Stilb; Dan Yang Huang; Almut Grenz; Svetlana Myssina; Michael Duszenko; Florian Lang; Dieter Häussinger; Volker Vallon; Thomas Wieder
Blunted apoptosis of erythrocytes from taurine transporter deficient mice.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2003;13(6):337-46.
2002: Zakayi Kabututu; Samuel K Martin; Tomoyoshi Nozaki; Shin-ichiro Kawazu; Tetsuya Okada; Craig Joe Munday; Michael Duszenko; Michael Lazarus; Lucy W Thuita; Yoshihiro Urade; Bruno Kilunga Kubata
Prostaglandin production from arachidonic acid and evidence for a 9,11-endoperoxide prostaglandin H2 reductase in Leishmania.
International journal for parasitology 2002;32(14):1693-700.
2002: Bruno Kilunga Kubata; Zakayi Kabututu; Tomoyoshi Nozaki; Craig Joe Munday; Shunichi Fukuzumi; Kei Ohkubo; Michael Lazarus; Toshihiko Maruyama; Samuel K Martin; Michael Duszenko; Yoshihiro Urade
A key role for old yellow enzyme in the metabolism of drugs by Trypanosoma cruzi.
The Journal of experimental medicine 2002;196(9):1241-51.
2002: Xuedong Kang; Alexander Szallies; Marc Rawer; Hartmut Echner; Michael Duszenko
GPI anchor transamidase of Trypanosoma brucei: in vitro assay of the recombinant protein and VSG anchor exchange.
Journal of cell science 2002;115(Pt 12):2529-39.
2002: Alexander Szallies; Bruno Kilunga Kubata; Michael Duszenko
A metacaspase of Trypanosoma brucei causes loss of respiration competence and clonal death in the yeast Saccharomyces cerevisiae.
FEBS letters 2002;517(1-3):144-50.
2000: Bruno Kilunga Kubata; Michael Duszenko; Zakayi Kabututu; Marc Rawer; Alexander Szallies; K Fujimori; Takashi Inui; Tomoyoshi Nozaki; K Yamashita; T Horii; Yoshihiro Urade; Osamu Hayaishi
Identification of a novel prostaglandin f(2alpha) synthase in Trypanosoma brucei.
The Journal of experimental medicine 2000;192(9):1327-38.
2000: K Steinborn; Alexander Szallies; Dieter Mecke; Michael Duszenko
Cloning, heterologous expression and kinetic analysis of glycerol kinase (TbGLK1) from Trypanosoma brucei.
Biological chemistry 2000;381(11):1071-7.
1999: Michael Duszenko; X Kang; U Böhme; R Hömke; M Lehner
In vitro translation in a cell-free system from Trypanosoma brucei yields glycosylated and glycosylphosphatidylinositol-anchored proteins.
European journal of biochemistry / FEBS 1999;266(3):789-97.
1999: V Kolb; F Amann; R R Schmidt; Michael Duszenko
Specific inhibition of an alpha-galactosyltransferase from Trypanosoma brucei by synthetic substrate analogues.
Glycoconjugate journal 1999;16(9):537-44.
1999: S Pingel; U Rheinweiler; V Kolb; Michael Duszenko
Purification and characterization of an alpha-galactosyltransferase from Trypanosoma brucei.
The Biochemical journal 1999;338 ( Pt 2)():545-51.
1998: U Wille; B Schade; Michael Duszenko
Characterization of glycerol uptake in bloodstream and procyclic forms of Trypanosoma brucei.
European journal of biochemistry / FEBS 1998;256(1):245-50.
1996: T Ziegler; R Dettmann; Michael Duszenko; V Kolb
Synthesis of octyl O- and S-glycosides related to the GPI anchor of Trypanosoma brucei and their in vitro galactosylation by trypanosomal alpha-galactosyltransferases.
Carbohydrate research 1996;295():7-23.
1996: U Wille; A Seyfang; Michael Duszenko
Glucose uptake occurs by facilitated diffusion in procyclic forms of Trypanosoma brucei.
European journal of biochemistry / FEBS 1996;236(1):228-33.
1996: P M Selzer; F Hesse; B Hamm-Kunzelmann; K Muhlstadt; H Echner; Michael Duszenko
Down regulation of S-adenosyl-L-methionine decarboxylase activity of Trypanosoma brucei during transition from long slender to short stumpy-like forms in axenic culture.
European journal of cell biology 1996;69(2):173-9.
1995: S Pingel; Robert A Field; M Lucia S Güther; Michael Duszenko; Michael A J Ferguson
The hydrophobic mannoside Man alpha 1-6Man alpha 1-S-(CH2)7-CH3 acts as an acceptor for the UDP-Gal:glycosylphosphatidylinositol anchor alpha 1,3-galactosyltransferase of Trypanosoma brucei.
The Biochemical journal 1995;309 ( Pt 3)():877-82.
1995: F Hesse; P M Selzer; K Mühlstädt; Michael Duszenko
A novel cultivation technique for long-term maintenance of bloodstream form trypanosomes in vitro.
Molecular and biochemical parasitology 1995;70(1-2):157-66.
1993: A Seyfang; Michael Duszenko
Functional reconstitution of the Trypanosoma brucei plasma-membrane D-glucose transporter.
European journal of biochemistry / FEBS 1993;214(2):593-7.
1992: S Pingel; Michael Duszenko
Identification of two distinct galactosyltransferase activities acting on the variant surface glycoprotein of Trypanosoma brucei.
The Biochemical journal 1992;283 ( Pt 2)():479-85.
1992: Michael Duszenko; K Mühlstädt; A Broder
Cysteine is an essential growth factor for Trypanosoma brucei bloodstream forms.
Molecular and biochemical parasitology 1992;50(2):269-73.
1991: A Seyfang; Michael Duszenko
Specificity of glucose transport in Trypanosoma brucei. Effective inhibition by phloretin and cytochalasin B.
European journal of biochemistry / FEBS 1991;202(1):191-6.
1991: P M Selzer; P Webster; Michael Duszenko
Influence of Ca2+ depletion on cytoskeleton and nucleolus morphology in Trypanosoma brucei.
European journal of cell biology 1991;56(1):104-12.
1990: A Seyfang; Dieter Mecke; Michael Duszenko
Degradation, recycling, and shedding of Trypanosoma brucei variant surface glycoprotein.
The Journal of protozoology 1990;37(6):546-52.
1990: B Hamm; A Schindler; Dieter Mecke; Michael Duszenko
Differentiation of Trypanosoma brucei bloodstream trypomastigotes from long slender to short stumpy-like forms in axenic culture.
Molecular and biochemical parasitology 1990;40(1):13-22.
1986: Michael Duszenko; Dieter Mecke
Inhibition of glyceraldehyde-3-phosphate dehydrogenase by pentalenolactone in Trypanosoma brucei.
Molecular and biochemical parasitology 1986;19(3):223-9.
1982: Michael Duszenko; H Balla; Dieter Mecke
Specific inactivation of glucose metabolism from eucaryotic cells by pentalenolactone.
Biochimica et biophysica acta 1982;714(2):344-50.