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Raymond Dwek

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Glycosylation

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Stuart T Perry; Emily M Plummer; Urban Ramstedt; Eric J Stavale; Kelly L Warfield; Dominic S Alonzi; Hitesh Batra; Michael D Buck; Terry D Butters; Raymond A Dwek; Kevin King; Brennan Klose; Steven M Lada; Raju A Penmasta; Sujan Shresta
An iminosugar with potent inhibition of dengue virus infection in vivo.
Kavitha Baruah; Thomas A Bowden; Max Crispin; Raymond A Dwek; Benjamin A Krishna; Christopher N Scanlan
Selective deactivation of serum IgG: a general strategy for the enhancement of monoclonal antibody receptor interactions.
Bevin Gangadharan; Bettina Kampa; Paul Klenerman; Jan Rossa; Robin Antrobus; Manisha Bapat; Eleanor Barnes; David Chittenden; Raymond A Dwek; Nicole Zitzmann
Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.

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All Publications

2013: Stuart T Perry; Emily M Plummer; Urban Ramstedt; Eric J Stavale; Kelly L Warfield; Dominic S Alonzi; Hitesh Batra; Michael D Buck; Terry D Butters; Raymond A Dwek; Kevin King; Brennan Klose; Steven M Lada; Raju A Penmasta; Sujan Shresta
An iminosugar with potent inhibition of dengue virus infection in vivo.
Antiviral research 2013;98(1):35-43.
2012: Kavitha Baruah; Thomas A Bowden; Max Crispin; Raymond A Dwek; Benjamin A Krishna; Christopher N Scanlan
Selective deactivation of serum IgG: a general strategy for the enhancement of monoclonal antibody receptor interactions.
Journal of molecular biology 2012;420(1-2):1-7.
2012: Bevin Gangadharan; Bettina Kampa; Paul Klenerman; Jan Rossa; Robin Antrobus; Manisha Bapat; Eleanor Barnes; David Chittenden; Raymond A Dwek; Nicole Zitzmann
Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.
PloS one 2012;7(6):e39603.
2011: Cristina Dorobantu; Raymond A Dwek; Catalin Lazar; alina macovei; Nicole Zitzmann; Norica Branza-Nichita
Cholesterol depletion of hepatoma cells impairs hepatitis B virus envelopment by altering the topology of the large envelope protein.
Journal of virology 2011;85(24):13373-83.
2011: Nikolay V Kukushkin; Raymond A Dwek; Dominic S Alonzi; Terry D Butters
Demonstration that endoplasmic reticulum-associated degradation of glycoproteins can occur downstream of processing by endomannosidase.
The Biochemical journal 2011;438(1):133-42.
2011: Thomas Whitfield; Philip C Biggin; Raymond A Dwek; Andrew J Miles; John Offer; Johanna C Scheinost; B A Wallace; Paul Wentworth; Nicole Zitzmann
The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein.
Molecular membrane biology 2011;28(5):254-64.
2011: Bevin Gangadharan; Robin Antrobus; David Chittenden; Jan Rossa; Manisha Bapat; Paul Klenerman; Eleanor Barnes; Raymond A Dwek; Nicole Zitzmann
New approaches for biomarker discovery: the search for liver fibrosis markers in hepatitis C patients.
Journal of proteome research 2011;10(5):2643-50.
2011: Camille Bonomelli; Dennis R Burton; Max Crispin; Katie J Doores; D Cameron Dunlop; Raymond A Dwek; Victoria Thaney; Christopher N Scanlan
The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.
PloS one 2011;6(8):e23521.
2010: Stephanie Pollock; Norica Branza Nichita; Annette Böhmer; Cristina Radulescu; Raymond A Dwek; Nicole Zitzmann
Polyunsaturated liposomes are antiviral against hepatitis B and C viruses and HIV by decreasing cholesterol levels in infected cells.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(40):17176-81.
2010: Raquel Montesino; Jeovanis Gil; Luis J González; Yasser Zamora; Louise Royle; Pauline M Rudd; Raymond A Dwek; David Harvey; José A Cremata
The N-glycosylation of classical swine fever virus E2 glycoprotein extracellular domain expressed in the milk of goat.
Archives of biochemistry and biophysics 2010;500(2):169-80.
2010: Katie J Doores; Camille Bonomelli; David Harvey; Snezana Vasiljevic; Raymond A Dwek; Dennis R Burton; Max Crispin; Christopher N Scanlan
Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(31):13800-5.
2010: D Cameron Dunlop; Camille Bonomelli; Fatma Mansab; Snezana Vasiljevic; Katie J Doores; Mark R Wormald; Angelina S Palma; Ten Feizi; David Harvey; Raymond A Dwek; Max Crispin; Christopher N Scanlan
Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans.
Glycobiology 2010;20(7):812-23.
2010: Stephanie Pollock; Robin Antrobus; Laura Newton; Bettina Kampa; Jan Rossa; Sally Latham; Norica Branza Nichita; Raymond A Dwek; Nicole Zitzmann
Uptake and trafficking of liposomes to the endoplasmic reticulum.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(6):1866-78.
2010: Ada Triguero; Gleysin Cabrera; Louise Royle; David Harvey; Pauline M Rudd; Raymond A Dwek; Muriel Bardor; Patrice Lerouge; José A Cremata
Chemical and enzymatic N-glycan release comparison for N-glycan profiling of monoclonal antibodies expressed in plants.
Analytical biochemistry 2010;400(2):173-83.
2010: David Harvey; Jaak Jaeken; Mike Butler; Alison J Armitage; Pauline M Rudd; Raymond A Dwek
Fragmentation of negative ions from N-linked carbohydrates, part 4. Fragmentation of complex glycans lacking substitution on the 6-antenna.
Journal of mass spectrometry : JMS 2010;45(5):528-35.
2010: Gayle Ritchie; David Harvey; Friederike Feldmann; Ute Stroeher; Heinz Feldmann; Louise Royle; Raymond A Dwek; Pauline M Rudd
Identification of N-linked carbohydrates from severe acute respiratory syndrome (SARS) spike glycoprotein.
Virology 2010;399(2):257-69.
2010: Stephanie D Boomkamp; J S Shane Rountree; David C A Neville; Raymond A Dwek; George W J Fleet; Terry D Butters
Lysosomal storage of oligosaccharide and glycosphingolipid in imino sugar treated cells.
Glycoconjugate journal 2010;27(3):297-308.
2010: Gayle Ritchie; David Harvey; Ute Stroeher; Friederike Feldmann; Heinz Feldmann; Victoria Wahl-Jensen; Louise Royle; Raymond A Dwek; Pauline M Rudd
Identification of N-glycans from Ebola virus glycoproteins by matrix-assisted laser desorption/ionisation time-of-flight and negative ion electrospray tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM 2010;24(5):571-85.
2010: Karen Muindi; Manuela Cernadas; Gerald F M Watts; Louise Royle; David C A Neville; Raymond A Dwek; Gurdyal S Besra; Pauline M Rudd; Terry D Butters; Michael B Brenner
Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d [corrected].
Proceedings of the National Academy of Sciences of the United States of America 2010;107(7):3052-7.
2010: Alina Macovei; Cristina Radulescu; Catalin Lazar; Stefana Petrescu; David Durantel; Raymond A Dwek; Nicole Zitzmann; Norica Branza Nichita
Hepatitis B virus requires intact caveolin-1 function for productive infection in HepaRG cells.
Journal of virology 2010;84(1):243-53.
2009: David Harvey; Max Crispin; Beryl E Moffatt; Sylvia L Smith; Robert B Sim; Pauline M Rudd; Raymond A Dwek
Identification of high-mannose and multiantennary complex-type N-linked glycans containing alpha-galactose epitopes from Nurse shark IgM heavy chain.
Glycoconjugate journal 2009;26(8):1055-64.
2009: Max Crispin; Veronica T Chang; David Harvey; Raymond A Dwek; Edward J Evans; David I Stuart; E Yvonne Jones; J Michael Lord; Robert Spooner; Simon J Davis
A human embryonic kidney 293T cell line mutated at the Golgi alpha-mannosidase II locus.
The Journal of biological chemistry 2009;284(32):21684-95.
2009: Philipp Luik; Chee Chew; Jussi Aittoniemi; Jason Chang; Paul Wentworth; Raymond A Dwek; Philip C Biggin; Catherine Vénien-Bryan; Nicole Zitzmann
The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(31):12712-6.
2009: David Harvey; Anthony H Merry; Louise Royle; Matthew P Campbell; Raymond A Dwek; Pauline M Rudd
Proposal for a standard system for drawing structural diagrams of N- and O-linked carbohydrates and related compounds.
Proteomics 2009;9(15):3796-801.
2009: Yunpeng Su; Louise Royle; Catherine M Radcliffe; David Harvey; Raymond A Dwek; Luisa Martinez-Pomares; Pauline M Rudd
Detailed N-glycan analysis of mannose receptor purified from murine spleen indicates tissue specific sialylation.
Biochemical and biophysical research communications 2009;384(4):436-43.
2009: Amy J Rawlings; Hannah Lomas; Adam W Pilling; Marvin J-R Lee; Dominic S Alonzi; J S Shane Rountree; Sarah F Jenkinson; George W J Fleet; Raymond A Dwek; John H Jones; Terry D Butters
Synthesis and biological characterisation of novel N-alkyl-deoxynojirimycin alpha-glucosidase inhibitors.
Chembiochem : a European journal of chemical biology 2009;10(6):1101-5.
2009: Mukram M Mackeen; Andrew Almond; Michael Deschamps; Ian Cumpstey; Antony J Fairbanks; Clarence Tsang; Pauline M Rudd; Terry D Butters; Raymond A Dwek; Mark R Wormald
The conformational properties of the Glc3Man unit suggest conformational biasing within the chaperone-assisted glycoprotein folding pathway.
Journal of molecular biology 2009;387(2):335-47.
2009: J S Shane Rountree; Terry D Butters; Mark R Wormald; Stephanie D Boomkamp; Raymond A Dwek; Naoki Asano; Kyoko Ikeda; Emma L Evinson; Robert J Nash; George W J Fleet
Design, synthesis, and biological evaluation of enantiomeric beta-N-acetylhexosaminidase inhibitors LABNAc and DABNAc as potential agents against Tay-Sachs and Sandhoff disease.
ChemMedChem 2009;4(3):378-92.
2009: David C A Neville; Raymond A Dwek; Terry D Butters
Development of a single column method for the separation of lipid- and protein-derived oligosaccharides.
Journal of proteome research 2009;8(2):681-7.
2009: Raquel Montesino; Jorge R Toledo; Oliberto Sanchez; Yasser Zamora; Maritza Barrera; Louise Royle; Pauline M Rudd; Raymond A Dwek; David Harvey; José A Cremata
N-glycosylation pattern of E2 glycoprotein from classical swine fever virus.
Journal of proteome research 2009;8(2):546-55.
2009: Maximiliano J Jimenez-Dalmaroni; Nengming Xiao; Adam L Corper; Petra Verdino; Gary D Ainge; Dave S Larsen; Gavin F Painter; Pauline M Rudd; Raymond A Dwek; Kasper Hoebe; Bruce Beutler; Ian A Wilson
Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2.
PloS one 2009;4(10):e7411.
2009: Ramamurthy Narayan; Bevin Gangadharan; Olivier Hantz; Robin Antrobus; Angela García; Raymond A Dwek; Nicole Zitzmann
Proteomic analysis of HepaRG cells: a novel cell line that supports hepatitis B virus infection.
Journal of proteome research 2009;8(1):118-22.
2008: Umi M Abd Hamid; Louise Royle; Radka Saldova; Catherine M Radcliffe; David Harvey; Sarah J Storr; María Pardo; Robin Antrobus; Caroline J Chapman; Nicole Zitzmann; John F Robertson; Raymond A Dwek; Pauline M Rudd
A strategy to reveal potential glycan markers from serum glycoproteins associated with breast cancer progression.
Glycobiology 2008;18(12):1105-18.
2008: Xiaojin Xu; Xueyong Zhu; Raymond A Dwek; James Stevens; Ian A Wilson
Structural characterization of the 1918 influenza virus H1N1 neuraminidase.
Journal of virology 2008;82(21):10493-501.
2008: Louise Royle; Elizabeth Matthews; Anthony Corfield; Monica Berry; Pauline M Rudd; Raymond A Dwek; Stephen D Carrington
Glycan structures of ocular surface mucins in man, rabbit and dog display species differences.
Glycoconjugate journal 2008;25(8):763-73.
2008: D Cameron Dunlop; Alexander Ulrich; Ben J Appelmelk; Dennis R Burton; Raymond A Dwek; Nicole Zitzmann; Christopher N Scanlan
Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
AIDS (London, England) 2008;22(16):2214-7.
2008: Stephanie Pollock; Raymond A Dwek; Dennis R Burton; Nicole Zitzmann
N-Butyldeoxynojirimycin is a broadly effective anti-HIV therapy significantly enhanced by targeted liposome delivery.
AIDS (London, England) 2008;22(15):1961-9.
2008: Martial Séveno; Gleysin Cabrera; Ada Triguero; Carole Burel; Jérome Leprince; Christophe Rihouey; Louis-Philippe Vézina; Marc-André D'Aoust; Pauline M Rudd; L Royle; Raymond A Dwek; David Harvey; Patrice Lerouge; José A Cremata; Muriel Bardor
Plant N-glycan profiling of minute amounts of material.
Analytical biochemistry 2008;379(1):66-72.
2008: Rena D Astronomo; Hing-Ken Lee; Christopher N Scanlan; Ralph Pantophlet; Cheng-Yuan Huang; Ian A Wilson; Ola Blixt; Raymond A Dwek; Chi-Huey Wong; Dennis R Burton
A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120.
Journal of virology 2008;82(13):6359-68.
2008: Elena Elliot-Smith; Anneliese O Speak; Emyr Lloyd-Evans; David A Smith; Aarnoud C van der Spoel; Mylvaganam Jeyakumar; Terry D Butters; Raymond A Dwek; Alessandra d'Azzo; Frances M Platt
Beneficial effects of substrate reduction therapy in a mouse model of GM1 gangliosidosis.
Molecular genetics and metabolism 2008;94(2):204-11.
2008: Sarah J Storr; Louise Royle; Caroline J Chapman; Umi M Abd Hamid; John F Robertson; Andrea Murray; Raymond A Dwek; Pauline M Rudd
The O-linked glycosylation of secretory/shed MUC1 from an advanced breast cancer patient's serum.
Glycobiology 2008;18(6):456-62.
2008: Matthew P Campbell; Louise Royle; Catherine M Radcliffe; Raymond A Dwek; Pauline M Rudd
GlycoBase and autoGU: tools for HPLC-based glycan analysis.
Bioinformatics (Oxford, England) 2008;24(9):1214-6.
2008: Stephen D Woodhouse; Caroline Smith; Maud Michelet; Norica Branza-Nichita; Mark Hussey; Raymond A Dwek; Nicole Zitzmann
Iminosugars in combination with interferon and ribavirin permanently eradicate noncytopathic bovine viral diarrhea virus from persistently infected cells.
Antimicrobial agents and chemotherapy 2008;52(5):1820-8.
2008: David Harvey; Louise Royle; Catherine M Radcliffe; Pauline M Rudd; Raymond A Dwek
Structural and quantitative analysis of N-linked glycans by matrix-assisted laser desorption ionization and negative ion nanospray mass spectrometry.
Analytical biochemistry 2008;376(1):44-60.
2008: Louise Royle; Matthew P Campbell; Catherine M Radcliffe; Dawn M White; David Harvey; Jodie L Abrahams; Yun-Gon Kim; George W Henry; Nancy A Shadick; Michael E Weinblatt; David M Lee; Pauline M Rudd; Raymond A Dwek
HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software.
Analytical biochemistry 2008;376(1):1-12.
2008: Christopher N Scanlan; Dennis R Burton; Raymond A Dwek
Making autoantibodies safe.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4081-2.
2008: Yun-Gon Kim; Dong-Sik Shin; Yung-Hun Yang; Geun Cheol Gil; Chung-Gyu Park; Yusuke Mimura; David K C Cooper; Pauline M Rudd; Raymond A Dwek; Yoon-Sik Lee; Byung-Gee Kim
High-throughput screening of glycan-binding proteins using miniature pig kidney N-glycan-immobilized beads.
Chemistry & biology 2008;15(3):215-23.
2008: Katy J McCann; Christian H Ottensmeier; Alice Callard; Catherine M Radcliffe; David Harvey; Raymond A Dwek; Pauline M Rudd; Brian J Sutton; Paul Hobby; Freda K Stevenson
Remarkable selective glycosylation of the immunoglobulin variable region in follicular lymphoma.
Molecular immunology 2008;45(6):1567-72.
2008: Joanna L Miller; Barend J M de Wet; Barend J M deWet; Luisa Martinez-Pomares; Catherine M Radcliffe; Raymond A Dwek; Pauline M Rudd; Siamon Gordon
The mannose receptor mediates dengue virus infection of macrophages.
PLoS pathogens 2008;4(2):e17.
2008: David A Priestman; Aarnoud C van der Spoel; Terry D Butters; Raymond A Dwek; Frances M Platt
N-butyldeoxynojirimycin causes weight loss as a result of appetite suppression in lean and obese mice.
Diabetes, obesity & metabolism 2008;10(2):159-66.
2008: Anand S Mehta; Ronald E Long; Mary Ann Comunale; Mengjun Wang; Lucy Rodemich; Jonathan Krakover; Ramila Philip; Jorge A Marrero; Raymond A Dwek; Timothy M Block
Increased levels of galactose-deficient anti-Gal immunoglobulin G in the sera of hepatitis C virus-infected individuals with fibrosis and cirrhosis.
Journal of virology 2008;82(3):1259-70.
2008: Dominic S Alonzi; David C A Neville; Robin H Lachmann; Raymond A Dwek; Terry D Butters
Glucosylated free oligosaccharides are biomarkers of endoplasmic- reticulum alpha-glucosidase inhibition.
The Biochemical journal 2008;409(2):571-80.
2008: Radka Saldova; Mark R Wormald; Raymond A Dwek; Pauline M Rudd
Glycosylation changes on serum glycoproteins in ovarian cancer may contribute to disease pathogenesis.
Disease markers 2008;25(4-5):219-32.
2007: Olga Gornik; Louise Royle; David Harvey; Catherine M Radcliffe; Radka Saldova; Raymond A Dwek; Pauline Rudd; Gordan Lauc
Changes of serum glycans during sepsis and acute pancreatitis.
Glycobiology 2007;17(12):1321-32.
2007: Radka Saldova; Louise Royle; Catherine M Radcliffe; Umi M Abd Hamid; Rachel Evans; James N Arnold; Rosamonde E Banks; Richard Hutson; David Harvey; Robin Antrobus; Stefana M Petrescu; Raymond A Dwek; Pauline M Rudd
Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG.
Glycobiology 2007;17(12):1344-56.
2007: Charlotte M Walden; Roger Sandhoff; Chia-Chen Chuang; Yildiz Yildiz; Terry D Butters; Raymond A Dwek; Frances M Platt; Aarnoud C van der Spoel
Accumulation of glucosylceramide in murine testis, caused by inhibition of beta-glucosidase 2: implications for spermatogenesis.
The Journal of biological chemistry 2007;282(45):32655-64.
2007: Bevin Gangadharan; Robin Antrobus; Raymond A Dwek; Nicole Zitzmann
Novel serum biomarker candidates for liver fibrosis in hepatitis C patients.
Clinical chemistry 2007;53(10):1792-9.
2007: Catalin Lazar; David Durantel; alina macovei; Nicole Zitzmann; Fabien Zoulim; Raymond A Dwek; Norica Branza-Nichita
Treatment of hepatitis B virus-infected cells with alpha-glucosidase inhibitors results in production of virions with altered molecular composition and infectivity.
Antiviral research 2007;76(1):30-7.
2007: Christopher N Scanlan; Gayle E Ritchie; Kavitha Baruah; Max Crispin; David Harvey; Bernhard Singer; Lothar Lucka; Mark R Wormald; Paul Wentworth; Nicole Zitzmann; Pauline M Rudd; Dennis R Burton; Raymond A Dwek
Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody.
Journal of molecular biology 2007;372(1):16-22.
2007: Eike Steinmann; Thomas Whitfield; Stephanie Kallis; Raymond A Dwek; Nicole Zitzmann; Thomas Pietschmann; Ralf Bartenschlager
Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus.
Hepatology (Baltimore, Md.) 2007;46(2):330-8.
2007: María Pardo; Angel García; Robin Antrobus; María José Blanco; Raymond A Dwek; Nicole Zitzmann
Biomarker discovery from uveal melanoma secretomes: identification of gp100 and cathepsin D in patient serum.
Journal of proteome research 2007;6(7):2802-11.
2007: Max Crispin; A Radu Aricescu; Veronica T Chang; E Yvonne Jones; David I Stuart; Raymond A Dwek; Simon J Davis; David Harvey
Disruption of alpha-mannosidase processing induces non-canonical hybrid-type glycosylation.
FEBS letters 2007;581(10):1963-8.
2007: Natasza E Ziółkowska; Shilpa R Shenoy; Barry R O'Keefe; James B McMahon; Kenneth Edward Palmer; Raymond A Dwek; Mark R Wormald; Alexander Wlodawer
Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin.
Proteins 2007;67(3):661-70.
2007: Christopher N Scanlan; John Offer; Nicole Zitzmann; Raymond A Dwek
Exploiting the defensive sugars of HIV-1 for drug and vaccine design.
Nature 2007;446(7139):1038-45.
2007: Yusuke Mimura; Yuka Mimura-Kimura; Katie Doores; Denise Golgher; Benjamin G Davis; Raymond A Dwek; Pauline M Rudd; Tim Elliott
Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(14):5983-8.
2007: Anneliese O Speak; Mariolina Salio; David C A Neville; Josette Fontaine; David A Priestman; Nick Platt; Tanya Heare; Terry D Butters; Raymond A Dwek; François Trottein; Mark A Exley; Vincenzo Cerundolo; Frances M Platt
Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(14):5971-6.
2007: María Pardo; Raymond A Dwek; Nicole Zitzmann
Proteomics in uveal melanoma research: opportunities and challenges in biomarker discovery.
Expert review of proteomics 2007;4(2):273-86.
2007: Cynthia Chapel; Céline Garcia; Birke Bartosch; Philippe Roingeard; Nicole Zitzmann; François-Loïc Cosset; Jean Dubuisson; Raymond A Dwek; Christian Trépo; Fabien Zoulim; David Durantel
Reduction of the infectivity of hepatitis C virus pseudoparticles by incorporation of misfolded glycoproteins induced by glucosidase inhibitors.
The Journal of general virology 2007;88(Pt 4):1133-43.
2007: Jean-Pyo Lee; Mylvaganam Jeyakumar; Rodolfo Gonzalez; Hiroto Takahashi; Pei-Jen Lee; Rena C Baek; Dan Clark; Heather Rose; Gerald Fu; Jonathan Clarke; Scott R McKercher; Jennifer Meerloo; Franz-Josef Muller; Kook In Park; Terry D Butters; Raymond A Dwek; Philip Schwartz; Gang Tong; David Wenger; Stuart A Lipton; Thomas N Seyfried; Frances M Platt; Evan Y Snyder
Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease.
Nature medicine 2007;13(4):439-47.
2007: Sílvia Barrabés; Lluís Pagès-Pons; Catherine M Radcliffe; Glòria Tabarés; Esther Fort; Louise Royle; David Harvey; Michel Moenner; Raymond A Dwek; Pauline M Rudd; Rafael de Llorens; Rosa Peracaula
Glycosylation of serum ribonuclease 1 indicates a major endothelial origin and reveals an increase in core fucosylation in pancreatic cancer.
Glycobiology 2007;17(4):388-400.
2007: Yoshinao Wada; Parastoo Azadi; Catherine E Costello; Anne Dell; Raymond A Dwek; Hildegard Geyer; Rudolf Geyer; Kazuaki Kakehi; Niclas Karlsson; Koichi Kato; Nana Kawasaki; Kay-Hooi Khoo; Soohyun Kim; Akihiro Kondo; Erika Lattova; Yehia Mechref; Eiji Miyoshi; Kazuyuki Nakamura; Hisashi Narimatsu; Milos V Novotny; Nicolle H Packer; Hélène Perreault; Jasna Peter-Katalinic; Gottfried Pohlentz; Vernon N Reinhold; Pauline M Rudd; Akemi Suzuki; Naoyuki Taniguchi
Comparison of the methods for profiling glycoprotein glycans--HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study.
Glycobiology 2007;17(4):411-22.
2007: Catherine M Radcliffe; James N Arnold; David M Suter; Mark R Wormald; David Harvey; Louise Royle; Yusuke Mimura; Yoshinobu Kimura; Robert B Sim; Susana Inogès; Mercedes Rodriguez-Calvillo; Natalia Zabalegui; Ascensión López-Díaz de Cerio; Kathleen N Potter; C Ian Mockridge; Raymond A Dwek; Maurizio Bendandi; Pauline M Rudd; Freda K Stevenson
Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor.
The Journal of biological chemistry 2007;282(10):7405-15.
2007: Veronica T Chang; Max Crispin; A Radu Aricescu; David Harvey; Joanne E Nettleship; Janet A Fennelly; Chao Yu; Kent S Boles; Edward J Evans; David I Stuart; Raymond A Dwek; E Yvonne Jones; Raymond J Owens; Simon J Davis
Glycoprotein structural genomics: solving the glycosylation problem.
Structure (London, England : 1993) 2007;15(3):267-73.
2007: Tanya Heare; Nicholas J Alp; David A Priestman; Ashok Kulkarni; Pankaj Qasba; Terry D Butters; Raymond A Dwek; K Clarke; K M Channon; Frances M Platt
Severe endothelial dysfunction in the aorta of a mouse model of Fabry disease; partial prevention by N-butyldeoxynojirimycin treatment.
Journal of inherited metabolic disease 2007;30(1):79-87.
2007: Marjolein Robijn; Carolien A M Koeleman; Manfred Wuhrer; Louise Royle; Rudolf Geyer; Raymond A Dwek; Pauline M Rudd; André M Deelder; Cornelis H Hokke
Targeted identification of a unique glycan epitope of Schistosoma mansoni egg antigens using a diagnostic antibody.
Molecular and biochemical parasitology 2007;151(2):148-61.
2007: James N Arnold; Mark R Wormald; Robert B Sim; Pauline M Rudd; Raymond A Dwek
The impact of glycosylation on the biological function and structure of human immunoglobulins.
Annual review of immunology 2007;25():21-50.
2006: Simon A Fry; Philippe E Van den Steen; Louise Royle; Mark R Wormald; Anthony J Leathem; Ghislain Opdenakker; James M McDonnell; Raymond A Dwek; Pauline M Rudd
Cancer-associated glycoforms of gelatinase B exhibit a decreased level of binding to galectin-3.
Biochemistry 2006;45(51):15249-58.
2006: Beatrijs D Oortwijn; Anja Roos; Louise Royle; Daniëlle J van Gijlswijk-Janssen; Maria C Faber-Krol; Jan-Willem Eijgenraam; Raymond A Dwek; Mohamed R Daha; Pauline M Rudd; Cees van Kooten
Differential glycosylation of polymeric and monomeric IgA: a possible role in glomerular inflammation in IgA nephropathy.
Journal of the American Society of Nephrology : JASN 2006;17(12):3529-39.
2006: Lone A Omtvedt; Louise Royle; Gunnar Husby; Knut Sletten; Catherine M Radcliffe; David Harvey; Raymond A Dwek; Pauline M Rudd
Glycan analysis of monoclonal antibodies secreted in deposition disorders indicates that subsets of plasma cells differentially process IgG glycans.
Arthritis and rheumatism 2006;54(11):3433-40.
2006: Stefanos A Tsiftsoglou; James N Arnold; Pietro Roversi; Max Crispin; Catherine M Radcliffe; Susan M Lea; Raymond A Dwek; Pauline M Rudd; Robert B Sim
Human complement factor I glycosylation: structural and functional characterisation of the N-linked oligosaccharides.
Biochimica et biophysica acta 2006;1764(11):1757-66.
2006: Rajesh Jayachandran; Catherine M Radcliffe; Louise Royle; David Harvey; Raymond A Dwek; Pauline M Rudd; Anjali A Karande
Oligosaccharides modulate the apoptotic activity of glycodelin.
Glycobiology 2006;16(11):1052-63.
2006: Stephan D Gadola; Jonathan Silk; Aruna Jeans; Petr A Illarionov; Mariolina Salio; Gurdyal S Besra; Raymond A Dwek; Terry D Butters; Frances M Platt; Vincenzo Cerundolo
Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases.
The Journal of experimental medicine 2006;203(10):2293-303.
2006: Muriel Bardor; Gleysin Cabrera; Pauline M Rudd; Raymond A Dwek; José A Cremata; Patrice Lerouge
Analytical strategies to investigate plant N-glycan profiles in the context of plant-made pharmaceuticals.
Current opinion in structural biology 2006;16(5):576-83.
2006: Angel García; Yotis A Senis; Robin Antrobus; Craig E Hughes; Raymond A Dwek; Steve P Watson; Nicole Zitzmann
A global proteomics approach identifies novel phosphorylated signaling proteins in GPVI-activated platelets: involvement of G6f, a novel platelet Grb2-binding membrane adapter.
Proteomics 2006;6(19):5332-43.
2006: Andrei J Petrescu; Mark R Wormald; Raymond A Dwek
Structural aspects of glycomes with a focus on N-glycosylation and glycoprotein folding.
Current opinion in structural biology 2006;16(5):600-7.
2006: Christopher G Knight; Nicole Zitzmann; Sripadi Prabhakar; Robin Antrobus; Raymond A Dwek; Holger F Hebestreit; Paul B Rainey
Unraveling adaptive evolution: how a single point mutation affects the protein coregulation network.
Nature genetics 2006;38(9):1015-22.
2006: Jasper J van Thor; Mukram Mackeen; Ilya Kuprov; Raymond A Dwek; Mark R Wormald
Chromophore structure in the photocycle of the cyanobacterial phytochrome Cph1.
Biophysical journal 2006;91(5):1811-22.
2006: María Pardo; Angel García; Benjamin Thomas; Antonio Piñeiro; Alexandre Akoulitchev; Raymond A Dwek; Nicole Zitzmann
The characterization of the invasion phenotype of uveal melanoma tumour cells shows the presence of MUC18 and HMG-1 metastasis markers and leads to the identification of DJ-1 as a potential serum biomarker.
International journal of cancer. Journal international du cancer 2006;119(5):1014-22.
2006: James N Arnold; Raymond A Dwek; Pauline M Rudd; Robert B Sim
Mannan binding lectin and its interaction with immunoglobulins in health and in disease.
Immunology letters 2006;106(2):103-10.
2006: Dennis R Burton; Raymond A Dwek
Immunology. Sugar determines antibody activity.
Science (New York, N.Y.) 2006;313(5787):627-8.
2006: alina macovei; Nicole Zitzmann; Catalin Lazar; Raymond A Dwek; Norica Branza-Nichita
Brefeldin A inhibits pestivirus release from infected cells, without affecting its assembly and infectivity.
Biochemical and biophysical research communications 2006;346(3):1083-90.
2006: Costin I Popescu; Alina Mares; Livia Sima; Nicole Zitzmann; Raymond A Dwek; Stefana M Petrescu
Productive folding of tyrosinase ectodomain is controlled by the transmembrane anchor.
The Journal of biological chemistry 2006;281(31):21682-9.
2006: Max Crispin; David Harvey; Veronica T Chang; Chao Yu; A Radu Aricescu; E Yvonne Jones; Simon J Davis; Raymond A Dwek; Pauline M Rudd
Inhibition of hybrid- and complex-type glycosylation reveals the presence of the GlcNAc transferase I-independent fucosylation pathway.
Glycobiology 2006;16(8):748-56.
2006: Philippe E Van den Steen; Ilse Van Aelst; Vibeke Hvidberg; Helene Piccard; Pierre Fiten; Christian Jacobsen; Søren K Moestrup; Simon Fry; Louise Royle; Mark R Wormald; Russell Wallis; Pauline M Rudd; Raymond A Dwek; Ghislain Opdenakker
The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bioavailability via inhibition and binding to cargo receptors.
The Journal of biological chemistry 2006;281(27):18626-37.
2006: Dawn Webber; Catherine M Radcliffe; Louise Royle; Gemma Tobiasen; Anthony H Merry; Allen L Rodgers; Edward D Sturrock; Mark R Wormald; David Harvey; Raymond A Dwek; Pauline M Rudd
Sialylation of urinary prothrombin fragment 1 is implicated as a contributory factor in the risk of calcium oxalate kidney stone formation.
The FEBS journal 2006;273(13):3024-37.
2006: Mukram Mackeen; Andrew Almond; Ian Cumpstey; Seth C Enis; Eriks Kupce; Terry D Butters; Antony J Fairbanks; Raymond A Dwek; Mark R Wormald
The importance of including local correlation times in the calculation of inter-proton distances from NMR measurements: ignoring local correlation times leads to significant errors in the conformational analysis of the Glc alpha1-2Glc alpha linkage by NMR spectroscopy.
Organic & biomolecular chemistry 2006;4(11):2241-6.
2006: Suzan Wopereis; Umi M Abd Hamid; Alison Critchley; Louise Royle; Raymond A Dwek; Eva Morava; Jules G Leroy; Bridget Wilcken; Aart J Lagerwerf; Karin M L C Huijben; Dirk J Lefeber; Pauline M Rudd; Ron A Wevers
Abnormal glycosylation with hypersialylated O-glycans in patients with Sialuria.
Biochimica et biophysica acta 2006;1762(6):598-607.
2006: Marc Jacquemin; Catherine M Radcliffe; Renaud Lavend'homme; Mark R Wormald; Luc VanderElst; G Wallays; J Dewaele; Désiré Collen; Jos Vermylen; Raymond A Dwek; Jean-Marie Saint-Remy; Pauline M Rudd; Mieke Dewerchin
Variable region heavy chain glycosylation determines the anticoagulant activity of a factor VIII antibody.
Journal of thrombosis and haemostasis : JTH 2006;4(5):1047-55.
2006: Charlotte M Walden; Terry D Butters; Raymond A Dwek; Frances M Platt; Aarnoud C van der Spoel
Long-term non-hormonal male contraception in mice using N-butyldeoxynojirimycin.
Human reproduction (Oxford, England) 2006;21(5):1309-15.
2006: David A Shore; Luc Teyton; Raymond A Dwek; Pauline M Rudd; Ian A Wilson
Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution.
Journal of molecular biology 2006;358(2):347-54.
2006: Katie J Doores; Yusuke Mimura; Raymond A Dwek; Pauline M Rudd; Tim Elliott; Benjamin G Davis
Direct deprotected glycosyl-asparagine ligation.
Chemical communications (Cambridge, England) 2006;(13):1401-3.
2006: Cynthia Chapel; Céline Garcia; Philippe Roingeard; Nicole Zitzmann; Jean Dubuisson; Raymond A Dwek; Christian Trépo; Fabien Zoulim; David Durantel
Antiviral effect of alpha-glucosidase inhibitors on viral morphogenesis and binding properties of hepatitis C virus-like particles.
The Journal of general virology 2006;87(Pt 4):861-71.
2006: Ghislain Opdenakker; Chris Dillen; Pierre Fiten; Erik Martens; Ilse Van Aelst; Philippe E Van den Steen; Inge Nelissen; Sofie Starckx; Francis J Descamps; Jialiang Hu; Helene Piccard; Jo Van Damme; Mark R Wormald; Pauline M Rudd; Raymond A Dwek
Remnant epitopes, autoimmunity and glycosylation.
Biochimica et biophysica acta 2006;1760(4):610-5.
2006: James N Arnold; Russell Wallis; Antony C Willis; David Harvey; Louise Royle; Raymond A Dwek; Pauline M Rudd; Robert B Sim
Interaction of mannan binding lectin with alpha2 macroglobulin via exposed oligomannose glycans: a conserved feature of the thiol ester protein family?
The Journal of biological chemistry 2006;281(11):6955-63.
2006: David Harvey; Raymond A Dwek; Pauline M Rudd
Determining the structure of glycan moieties by mass spectrometry.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2006;Chapter 12():Unit 12.7.
2006: Louise Royle; Raymond A Dwek; Pauline M Rudd
Determining the structure of oligosaccharides N- and O-linked to glycoproteins.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2006;Chapter 12():Unit 12.6.
2006: Timothy M Block; Anand S Mehta; Baruch S Blumberg; Raymond A Dwek
Does rapid oligomerization of hepatitis B envelope proteins play a role in resistance to proteasome degradation and enhance chronicity?
DNA and cell biology 2006;25(3):165-70.
2006: Yun-Gon Kim; Sun-Young Kim; Young-Mi Hur; Hwang Soo Joo; Junho Chung; Dong-Sup Lee; Louise Royle; Pauline M Rudd; Raymond A Dwek; David Harvey; Byung-Gee Kim
The identification and characterization of xenoantigenic nonhuman carbohydrate sequences in membrane proteins from porcine kidney.
Proteomics 2006;6(4):1133-42.
2006: Glòria Tabarés; Catherine M Radcliffe; Sílvia Barrabés; Manel Ramírez; R Núria Aleixandre; Wolfgang Hoesel; Raymond A Dwek; Pauline M Rudd; Rosa Peracaula; Rafael de Llorens
Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA.
Glycobiology 2006;16(2):132-45.
2006: George Patargias; Nicole Zitzmann; Raymond A Dwek; Wolfgang B Fischer
Protein-protein interactions: modeling the hepatitis C virus ion channel p7.
Journal of medicinal chemistry 2006;49(2):648-55.
2006: Edward Norris-Cervetto; Terry D Butters; Catherine Martin; Szabolcs Modok; Raymond A Dwek; Richard Callaghan
Can P-glycoprotein influence the bioavailability of iminosugar-based glucosylceramide synthase inhibitors?
European journal of pharmacology 2006;530(3):195-204.
2006: Louise Royle; Catherine M Radcliffe; Raymond A Dwek; Pauline M Rudd
Detailed structural analysis of N-glycans released from glycoproteins in SDS-PAGE gel bands using HPLC combined with exoglycosidase array digestions.
Methods in molecular biology (Clifton, N.J.) 2006;347():125-43.
2005: Yves Blériot; Dirk Gretzke; Thomas M Krülle; Terry D Butters; Raymond A Dwek; Robert J Nash; Naoki Asano; George W J Fleet
Looking glass inhibitors: efficient synthesis and biological evaluation of D-deoxyfuconojirimycin.
Carbohydrate research 2005;340(18):2713-8.
2005: Alison Simmons; Bevin Gangadharan; Ashleigh Hodges; Katherine Sharrocks; Sripadi Prabhakar; Angel García; Raymond A Dwek; Nicole Zitzmann; Andrew McMichael
Nef-mediated lipid raft exclusion of UbcH7 inhibits Cbl activity in T cells to positively regulate signaling.
Immunity 2005;23(6):621-34.
2005: María Pardo; Angel García; Benjamin Thomas; Antonio Piñeiro; Alexandre Akoulitchev; Raymond A Dwek; Nicole Zitzmann
Proteome analysis of a human uveal melanoma primary cell culture by 2-DE and MS.
Proteomics 2005;5(18):4980-93.
2005: Angel García; Steve P Watson; Raymond A Dwek; Nicole Zitzmann
Applying proteomics technology to platelet research.
Mass spectrometry reviews 2005;24(6):918-30.
2005: Ender Simsek; Anand Mehta; Tianlun Zhou; Raymond A Dwek; Timothy M Block
Hepatitis B virus large and middle glycoproteins are degraded by a proteasome pathway in glucosidase-inhibited cells but not in cells with functional glucosidase enzyme.
Journal of virology 2005;79(20):12914-20.
2005: Terry D Butters; Raymond A Dwek; Frances M Platt
Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses.
Glycobiology 2005;15(10):43R-52R.
2005: Yunpeng Su; Talitha Bakker; James Harris; Clarence Tsang; Gordon D Brown; Mark R Wormald; Siamon Gordon; Raymond A Dwek; Pauline M Rudd; Luisa Martinez-Pomares
Glycosylation influences the lectin activities of the macrophage mannose receptor.
The Journal of biological chemistry 2005;280(38):32811-20.
2005: Mylvaganam Jeyakumar; Raymond A Dwek; Terry D Butters; Frances M Platt
Storage solutions: treating lysosomal disorders of the brain.
Nature reviews. Neuroscience 2005;6(9):713-25.
2005: James N Arnold; Mark R Wormald; David M Suter; Catherine M Radcliffe; David Harvey; Raymond A Dwek; Pauline M Rudd; Robert B Sim
Human serum IgM glycosylation: identification of glycoforms that can bind to mannan-binding lectin.
The Journal of biological chemistry 2005;280(32):29080-7.
2005: Lidija Jerkovic; Andreas F Voegele; Sabine Chwatal; Florian Kronenberg; Catherine M Radcliffe; Mark R Wormald; Eva M Lobentanz; Benjie Ezeh; Patricia Eller; Norbert Dejori; Benjamin Dieplinger; Friedrich Lottspeich; Wolfgang Sattler; Manfred Uhr; Karl Mechtler; Raymond A Dwek; Pauline M Rudd; Gottfried Baier; Hans Dieplinger
Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression.
Journal of proteome research 2005;4(3):889-99.
2005: Costin I Popescu; Crina Paduraru; Raymond A Dwek; Stefana M Petrescu
Soluble tyrosinase is an endoplasmic reticulum (ER)-associated degradation substrate retained in the ER by calreticulin and BiP/GRP78 and not calnexin.
The Journal of biological chemistry 2005;280(14):13833-40.
2005: Ryota Suganuma; Charlotte M Walden; Terry D Butters; Frances M Platt; Raymond A Dwek; Ryuzo Yanagimachi; Aarnoud C van der Spoel
Alkylated imino sugars, reversible male infertility-inducing agents, do not affect the genetic integrity of male mouse germ cells during short-term treatment despite induction of sperm deformities.
Biology of reproduction 2005;72(4):805-13.
2005: Gabriela Negroiu; Raymond A Dwek; Stefana M Petrescu
Tyrosinase-related protein-2 and -1 are trafficked on distinct routes in B16 melanoma cells.
Biochemical and biophysical research communications 2005;328(4):914-21.
2005: B Jorgensen-Tye; Jean-Pierre Levesque; L Royle; R Doyonnas; J Y-H Chan; Raymond A Dwek; Pauline M Rudd; David Harvey; Paul J Simmons; Suzanne M Watt
Epitope recognition of antibodies that define the sialomucin, endolyn (CD164), a negative regulator of haematopoiesis.
Tissue antigens 2005;65(3):220-39.
2005: Dirk Zajonc; Max Crispin; Thomas A Bowden; David C Young; Tan-Yun Cheng; Jingdan Hu; Catherine E Costello; Pauline M Rudd; Raymond A Dwek; Marvin J Miller; Michael B Brenner; D Branch Moody; Ian A Wilson
Molecular mechanism of lipopeptide presentation by CD1a.
Immunity 2005;22(2):209-19.
2005: Timothy M Block; Mary Ann Comunale; Melissa Lowman; Laura F Steel; Patrick R Romano; Claus J Fimmel; Bud C Tennant; W Thomas London; Alison A Evans; Baruch S Blumberg; Raymond A Dwek; Taj S Mattu; Anand S Mehta
Use of targeted glycoproteomics to identify serum glycoproteins that correlate with liver cancer in woodchucks and humans.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(3):779-84.
2005: Frances M Platt; Mylvaganam Jeyakumar; Ulrika Andersson; Raymond A Dwek; Terry D Butters
New developments in treating glycosphingolipid storage diseases.
Advances in experimental medicine and biology 2005;564():117-26.
2005: Simon A Fry; Philippe E Van den Steen; Louise Royle; Mark R Wormald; Anthony J Leathem; Ghislain Opdenakker; Pauline M Rudd; Raymond A Dwek
Differential glycosylation of gelatinase B from neutrophils and breast cancer cells.
Advances in experimental medicine and biology 2005;564():103-12.
2005: Yusuke Mimura; Denise Golgher; Yuka Mimura-Kimura; Raymond A Dwek; Pauline M Rudd; Tim Elliott
Immunogenicity of calreticulin-bound murine leukemia virus glycoprotein gp90.
Advances in experimental medicine and biology 2005;564():85-94.
2005: David A Shore; Ian A Wilson; Raymond A Dwek; Pauline M Rudd
Glycosylation and the function of the T cell co-receptor CD8.
Advances in experimental medicine and biology 2005;564():71-84.
2005: James N Arnold; Louise Royle; Raymond A Dwek; Pauline M Rudd; Robert B Sim
Human immunoglobulin glycosylation and the lectin pathway of complement activation.
Advances in experimental medicine and biology 2005;564():27-43.
2005: Yunpeng Roc Su; Clarence Tsang; Talitha Bakker; James Harris; Siamon Gordon; Raymond A Dwek; Luisa Martinez-Pomares; Pauline M Rudd
Glycosylation influences the ligand binding activities of mannose receptor.
Advances in experimental medicine and biology 2005;564():25-6.
2005: Christopher N Scanlan; Daniel A Calarese; Hing-Ken Lee; Ola Blixt; Chi-Huey Wong; Ian Wilson; Dennis Burton; Raymond A Dwek; Pauline Rudd
Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design.
Advances in experimental medicine and biology 2005;564():7-8.
2005: D Pavlovic; W Fischer; M Hussey; David Durantel; Sandra Durantel; Norica Branza-Nichita; S Woodhouse; Raymond A Dwek; Nicole Zitzmann
Long alkylchain iminosugars block the HCV p7 ion channel.
Advances in experimental medicine and biology 2005;564():3-4.
2005: Nicole Zitzmann; Timothy Block; Anund Methta; Pauline Rudd; Dennis Burton; Ian Wilson; Frances Platt; Terry D Butters; Raymond A Dwek
Glycosylation: disease targets and therapy.
Advances in experimental medicine and biology 2005;564():1-2.
2004: James N Arnold; Catherine M Radcliffe; Mark R Wormald; Louise Royle; David Harvey; Max Crispin; Raymond A Dwek; Robert B Sim; Pauline M Rudd
The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(11):6831-40.
2004: Jo O'Leary; Catherine M Radcliffe; Antony C Willis; Raymond A Dwek; Pauline M Rudd; A Kristina Downing
Identification and removal of O-linked and non-covalently linked sugars from recombinant protein produced using Pichia pastoris.
Protein expression and purification 2004;38(2):217-27.
2004: María Pardo; Antonio Piñeiro; María de la Fuente; Angel García; Sripadi Prabhakar; Nicole Zitzmann; Raymond A Dwek; Manuel Sánchez-Salorio; Fernando Domínguez; Carmen Capeans
Abnormal cell cycle regulation in primary human uveal melanoma cultures.
Journal of cellular biochemistry 2004;93(4):708-20.
2004: Mylvaganam Jeyakumar; A David Smith; Ian M Williams; Mario Cortina Borja; David C A Neville; Terry D Butters; Raymond A Dwek; Frances M Platt
NSAIDs increase survival in the Sandhoff disease mouse: synergy with N-butyldeoxynojirimycin.
Annals of neurology 2004;56(5):642-9.
2004: Michael A Simpson; Harold Cross; christos proukakis; David A Priestman; David C A Neville; Gabriele Reinkensmeier; Heng Wang; Max Wiznitzer; Kay Gurtz; Argyro Verganelaki; Anna Pryde; Michael A Patton; Raymond A Dwek; Terry D Butters; Frances M Platt; Andrew H Crosby
Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase.
Nature genetics 2004;36(11):1225-9.
2004: Pauline M Rudd; Mark R Wormald; Raymond A Dwek
Sugar-mediated ligand-receptor interactions in the immune system.
Trends in biotechnology 2004;22(10):524-30.
2004: Edward Norris-Cervetto; Richard Callaghan; Frances M Platt; Raymond A Dwek; Terry D Butters
Inhibition of glucosylceramide synthase does not reverse drug resistance in cancer cells.
The Journal of biological chemistry 2004;279(39):40412-8.
2004: Gang Tian; David Wilcockson; V Hugh Perry; Pauline M Rudd; Raymond A Dwek; Frances M Platt; Nick Platt
Inhibition of alpha-glucosidases I and II increases the cell surface expression of functional class A macrophage scavenger receptor (SR-A) by extending its half-life.
The Journal of biological chemistry 2004;279(38):39303-9.
2004: Chu-Yi Yu; Naoki Asano; Kyoko Ikeda; Mei-Xiang Wang; Terry D Butters; Mark R Wormald; Raymond A Dwek; Ana L Winters; Robert J Nash; George W J Fleet
Looking glass inhibitors: L-DMDP, a more potent and specific inhibitor of alpha-glucosidases than the enantiomeric natural product DMDP.
Chemical communications (Cambridge, England) 2004;(17):1936-7.
2004: Isam Khalaila; Jasna Peter-Katalinic; Clarence Tsang; Catherine M Radcliffe; Eliahu D Aflalo; David Harvey; Raymond A Dwek; Pauline M Rudd; Amir Sagi
Structural characterization of the N-glycan moiety and site of glycosylation in vitellogenin from the decapod crustacean Cherax quadricarinatus.
Glycobiology 2004;14(9):767-74.
2004: David C A Neville; Virginie Coquard; David A Priestman; Daniëlle te Vruchte; Dan J Sillence; Raymond A Dwek; Frances M Platt; Terry D Butters
Analysis of fluorescently labeled glycosphingolipid-derived oligosaccharides following ceramide glycanase digestion and anthranilic acid labeling.
Analytical biochemistry 2004;331(2):275-82.
2004: Robin H Lachmann; Daniëlle te Vruchte; Emyr Lloyd-Evans; Gabriele Reinkensmeier; Dan J Sillence; Luisa Fernandez-Guillen; Raymond A Dwek; Terry D Butters; Timothy M Cox; Frances M Platt
Treatment with miglustat reverses the lipid-trafficking defect in Niemann-Pick disease type C.
Neurobiology of disease 2004;16(3):654-8.
2004: Ulrika Andersson; David Smith; Mylvaganam Jeyakumar; Terry D Butters; Mario Cortina Borja; Raymond A Dwek; Frances M Platt
Improved outcome of N-butyldeoxygalactonojirimycin-mediated substrate reduction therapy in a mouse model of Sandhoff disease.
Neurobiology of disease 2004;16(3):506-15.
2004: Howard R Mellor; David C A Neville; David Harvey; Frances M Platt; Raymond A Dwek; Terry D Butters
Cellular effects of deoxynojirimycin analogues: inhibition of N-linked oligosaccharide processing and generation of free glucosylated oligosaccharides.
The Biochemical journal 2004;381(Pt 3):867-75.
2004: Howard R Mellor; David C A Neville; David Harvey; Frances M Platt; Raymond A Dwek; Terry D Butters
Cellular effects of deoxynojirimycin analogues: uptake, retention and inhibition of glycosphingolipid biosynthesis.
The Biochemical journal 2004;381(Pt 3):861-6.
2004: Norica Branza-Nichita; Catalin Lazar; Raymond A Dwek; Nicole Zitzmann
Role of N-glycan trimming in the folding and secretion of the pestivirus protein E(rns).
Biochemical and biophysical research communications 2004;319(2):655-62.
2004: Daniëlle te Vruchte; Emyr Lloyd-Evans; Robert Jan Veldman; David C A Neville; Raymond A Dwek; Frances M Platt; Wim J van Blitterswijk; Dan J Sillence
Accumulation of glycosphingolipids in Niemann-Pick C disease disrupts endosomal transport.
The Journal of biological chemistry 2004;279(25):26167-75.
2004: Yoram Tekoah; Kisung Ko; Hilary Koprowski; David Harvey; Mark R Wormald; Raymond A Dwek; Pauline M Rudd
Controlled glycosylation of therapeutic antibodies in plants.
Archives of biochemistry and biophysics 2004;426(2):266-78.
2004: Pamela A Wearsch; Claude Jakob; Antonio Vallin; Raymond A Dwek; Pauline M Rudd; Peter Cresswell
Major histocompatibility complex class I molecules expressed with monoglucosylated N-linked glycans bind calreticulin independently of their assembly status.
The Journal of biological chemistry 2004;279(24):25112-21.
2004: Anand S Mehta; Baohua Gu; Bertha Conyers; Serguey Ouzounov; Lijuan Wang; Robert M Moriarty; Raymond A Dwek; Timothy M Block
alpha-Galactosylceramide and novel synthetic glycolipids directly induce the innate host defense pathway and have direct activity against hepatitis B and C viruses.
Antimicrobial agents and chemotherapy 2004;48(6):2085-90.
2004: Max Crispin; Gayle E Ritchie; Alison J Critchley; B Paul Morgan; Ian A Wilson; Raymond A Dwek; Robert B Sim; Pauline M Rudd
Monoglucosylated glycans in the secreted human complement component C3: implications for protein biosynthesis and structure.
FEBS letters 2004;566(1-3):270-4.
2004: Angel García; Sripadi Prabhakar; Sascha C Hughan; Tom W Anderson; Chris J Brock; Andrew C Pearce; Raymond A Dwek; Steve P Watson; Holger F Hebestreit; Nicole Zitzmann
Differential proteome analysis of TRAP-activated platelets: involvement of DOK-2 and phosphorylation of RGS proteins.
Blood 2004;103(6):2088-95.
2004: Angel García; Sripadi Prabhakar; Chris J Brock; Andrew C Pearce; Raymond A Dwek; Steve P Watson; Holger F Hebestreit; Nicole Zitzmann
Extensive analysis of the human platelet proteome by two-dimensional gel electrophoresis and mass spectrometry.
Proteomics 2004;4(3):656-68.
2004: Ulrika Andersson; Gabriele Reinkensmeier; Terry D Butters; Raymond A Dwek; Frances M Platt
Inhibition of glycogen breakdown by imino sugars in vitro and in vivo.
Biochemical pharmacology 2004;67(4):697-705.
2004: Hing-Ken Lee; Christopher N Scanlan; Cheng-Yuan Huang; Aileen Y Chang; Daniel A Calarese; Raymond A Dwek; Pauline M Rudd; Dennis R Burton; Ian A Wilson; Chi-Huey Wong
Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody.
Angewandte Chemie (International ed. in English) 2004;43(8):1000-3.
2004: Petra Lukacik; Pietro Roversi; Jennifer White; Dirk Esser; Geoffrey P Smith; Jason Billington; P A Williams; Pauline M Rudd; Mark R Wormald; David Harvey; Max Crispin; Catherine M Radcliffe; Raymond A Dwek; David J Evans; B Paul Morgan; R A G Smith; Susan M Lea
Complement regulation at the molecular level: the structure of decay-accelerating factor.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(5):1279-84.
2004: David Durantel; Sandra Carrouée-Durantel; Norica Branza-Nichita; Raymond A Dwek; Nicole Zitzmann
Effects of interferon, ribavirin, and iminosugar derivatives on cells persistently infected with noncytopathic bovine viral diarrhea virus.
Antimicrobial agents and chemotherapy 2004;48(2):497-504.
2004: Andrei J Petrescu; Adina L Milac; Stefana M Petrescu; Raymond A Dwek; Mark R Wormald
Statistical analysis of the protein environment of N-glycosylation sites: implications for occupancy, structure, and folding.
Glycobiology 2004;14(2):103-14.
2004: Deborah Elstein; Carla E M Hollak; johannes aerts; Sonja van Weely; M Maas; Timothy M Cox; Robin H Lachmann; Martin Hrebicek; Frances M Platt; Terry D Butters; Raymond A Dwek; Ari Zimran
Sustained therapeutic effects of oral miglustat (Zavesca, N-butyldeoxynojirimycin, OGT 918) in type I Gaucher disease.
Journal of inherited metabolic disease 2004;27(6):757-66.
2004: Lone A Omtvedt; Louise Royle; Gunnar Husby; K Sletten; Catherine M Radcliffe; Raymond A Dwek; Pauline M Rudd; David Harvey
Artefacts formed by addition of urea to N-linked glycans released with peptide-N-glycosidase F for analysis by mass spectrometry.
Rapid communications in mass spectrometry : RCM 2004;18(19):2357-9.
2003: Catalin Lazar; Nicole Zitzmann; Raymond A Dwek; Norica Branza-Nichita
The pestivirus E(rns) glycoprotein interacts with E2 in both infected cells and mature virions.
Virology 2003;314(2):696-705.
2003: Michael Butler; Dulce Quelhas; Alison J Critchley; Hubert A Carchon; Holger F Hebestreit; Richard G Hibbert; Laura Vilarinho; Elisa Leão Teles; Gert Matthijs; Els Schollen; Pablo F Argibay; David Harvey; Raymond A Dwek; Jaak Jaeken; Pauline M Rudd
Detailed glycan analysis of serum glycoproteins of patients with congenital disorders of glycosylation indicates the specific defective glycan processing step and provides an insight into pathogenesis.
Glycobiology 2003;13(9):601-22.
2003: Howard R Mellor; Frances M Platt; Raymond A Dwek; Terry D Butters
Membrane disruption and cytotoxicity of hydrophobic N-alkylated imino sugars is independent of the inhibition of protein and lipid glycosylation.
The Biochemical journal 2003;374(Pt 2):307-14.
2003: Gabriela Negroiu; Raymond A Dwek; Stefana M Petrescu
The inhibition of early N-glycan processing targets TRP-2 to degradation in B16 melanoma cells.
The Journal of biological chemistry 2003;278(29):27035-42.
2003: Anthony H Merry; Robert J C Gilbert; David A Shore; Louise Royle; Olga Miroshnychenko; Mai Vuong; Mark R Wormald; David Harvey; Raymond A Dwek; Brendan J Classon; Pauline M Rudd; Simon J Davis
O-glycan sialylation and the structure of the stalk-like region of the T cell co-receptor CD8.
The Journal of biological chemistry 2003;278(29):27119-28.
2003: Daniel A Calarese; Christopher N Scanlan; Michael B Zwick; Songpon Deechongkit; Yusuke Mimura; Renate Kunert; Ping Zhu; Mark R Wormald; Robyn L Stanfield; Kenneth H Roux; Jeffery W Kelly; Pauline M Rudd; Raymond A Dwek; Hermann Katinger; Dennis R Burton; Ian A Wilson
Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.
Science (New York, N.Y.) 2003;300(5628):2065-71.
2003: Kisung Ko; Yoram Tekoah; Pauline M Rudd; David Harvey; Raymond A Dwek; Sergei Spitsin; Cathleen Hanlon; Charles Rupprecht; Bernhard Dietzschold; Maxim Golovkin; Hilary Koprowski
Function and glycosylation of plant-derived antiviral monoclonal antibody.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):8013-8.
2003: Rosa Peracaula; Glòria Tabarés; Louise Royle; David Harvey; Raymond A Dwek; Pauline M Rudd; Rafael de Llorens
Altered glycosylation pattern allows the distinction between prostate-specific antigen (PSA) from normal and tumor origins.
Glycobiology 2003;13(6):457-70.
2003: Louise Royle; Anja Roos; David Harvey; Mark R Wormald; Daniëlle J van Gijlswijk-Janssen; El-Rashdy M Redwan; Ian A Wilson; Mohamed R Daha; Raymond A Dwek; Pauline M Rudd
Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems.
The Journal of biological chemistry 2003;278(22):20140-53.
2003: Frances M Platt; Mylvaganam Jeyakumar; Ulrika Andersson; Tanya Heare; Raymond A Dwek; Terry D Butters
Substrate reduction therapy in mouse models of the glycosphingolipidoses.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2003;358(1433):947-54.
2003: Terry D Butters; Howard R Mellor; Keishi Narita; Raymond A Dwek; Frances M Platt
Small-molecule therapeutics for the treatment of glycolipid lysosomal storage disorders.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2003;358(1433):927-45.
2003: Davor Pavlović; David C A Neville; Olivier Argaud; Baruch S Blumberg; Raymond A Dwek; Wolfgang B Fischer; Nicole Zitzmann
The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):6104-8.
2003: Laura F Steel; Donna Shumpert; Michael Trotter; Steven H Seeholzer; Alison A Evans; W Thomas London; Raymond A Dwek; Timothy M Block
A strategy for the comparative analysis of serum proteomes for the discovery of biomarkers for hepatocellular carcinoma.
Proteomics 2003;3(5):601-9.
2003: Rosa Peracaula; Louise Royle; Glòria Tabares; Goretti Mallorqui-Fernández; Sílvia Barrabés; David Harvey; Raymond A Dwek; Pauline M Rudd; Rafael de Llorens
Glycosylation of human pancreatic ribonuclease: differences between normal and tumor states.
Glycobiology 2003;13(4):227-44.
2003: Mylvaganam Jeyakumar; R Thomas; E Elliot-Smith; D A Smith; Aarnoud C van der Spoel; Alessandra d'Azzo; V Hugh Perry; Terry D Butters; Raymond A Dwek; Frances M Platt
Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis.
Brain : a journal of neurology 2003;126(Pt 4):974-87.
2003: Soohyun Kim; Soo Kyung Hwang; Raymond A Dwek; Pauline M Rudd; Yeong Hee Ahn; Eun-Hee Kim; Chaejoon Cheong; Seung Il Kim; Nam Sook Park; Sang Mong Lee
Structural determination of the N-glycans of a lepidopteran arylphorin reveals the presence of a monoglucosylated oligosaccharide in the storage protein.
Glycobiology 2003;13(3):147-57.
2003: Stefana M Petrescu; Costin I Popescu; Andrei J Petrescu; Raymond A Dwek
The glycosylation of tyrosinase in melanoma cells and the effect on antigen presentation.
Advances in experimental medicine and biology 2003;535():257-69.
2003: Terry D Butters; Raymond A Dwek; Frances M Platt
New therapeutics for the treatment of glycosphingolipid lysosomal storage diseases.
Advances in experimental medicine and biology 2003;535():219-26.
2003: Christopher N Scanlan; Ralph Pantophlet; Mark R Wormald; Erica Ollmann Saphire; Daniel A Calarese; Robyn L Stanfield; Ian A Wilson; Hermann Katinger; Raymond A Dwek; Dennis R Burton; Pauline M Rudd
The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12.
Advances in experimental medicine and biology 2003;535():205-18.
2003: Erica Ollmann Saphire; Robyn L Stanfield; Max Crispin; Garrett Morris; Michael B Zwick; Ralph Pantophlet; Paul W H I Parren; Pauline M Rudd; Raymond A Dwek; Dennis R Burton; Ian A Wilson
Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design.
Advances in experimental medicine and biology 2003;535():55-66.
2003: Terry D Butters; Raymond A Dwek; Frances M Platt
Therapeutic applications of imino sugars in lysosomal storage disorders.
Current topics in medicinal chemistry 2003;3(5):561-74.
2003: Majlis Svensson; Björn Frendeus; Terry D Butters; Frances Platt; Raymond A Dwek; Catharina Svanborg
Glycolipid depletion in antimicrobial therapy.
Molecular microbiology 2003;47(2):453-61.
2002: Aarnoud C van der Spoel; Mylvaganam Jeyakumar; Terry D Butters; Harry M Charlton; Harry D Moore; Raymond A Dwek; Frances M Platt
Reversible infertility in male mice after oral administration of alkylated imino sugars: a nonhormonal approach to male contraception.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):17173-8.
2002: Lorella Navazio; Manuela Miuzzo; Louise Royle; Barbara Baldan; Serena Varotto; Anthony H Merry; David Harvey; Raymond A Dwek; Pauline M Rudd; Paola Mariani
Monitoring endoplasmic reticulum-to-Golgi traffic of a plant calreticulin by protein glycosylation analysis.
Biochemistry 2002;41(48):14141-9.
2002: Philippe E Van den Steen; Bénédicte Dubois; Inge Nelissen; Pauline M Rudd; Raymond A Dwek; Ghislain Opdenakker
Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9).
Critical reviews in biochemistry and molecular biology 2002;37(6):375-536.
2002: Anand Mehta; Bertha Conyers; D Lorne J Tyrrell; Kathie-Anne Walters; Graham A Tipples; Raymond A Dwek; Timothy M Block
Structure-activity relationship of a new class of anti-hepatitis B virus agents.
Antimicrobial agents and chemotherapy 2002;46(12):4004-8.
2002: Catherine M Radcliffe; Gundo Diedrich; David Harvey; Raymond A Dwek; Peter Cresswell; Pauline M Rudd
Identification of specific glycoforms of major histocompatibility complex class I heavy chains suggests that class I peptide loading is an adaptation of the quality control pathway involving calreticulin and ERp57.
The Journal of biological chemistry 2002;277(48):46415-23.
2002: Dan J Sillence; Vishwajeet Puri; David L Marks; Terry D Butters; Raymond A Dwek; Richard E Pagano; Frances M Platt
Glucosylceramide modulates membrane traffic along the endocytic pathway.
Journal of lipid research 2002;43(11):1837-45.
2002: Pauline M Rudd; Anthony H Merry; Mark R Wormald; Raymond A Dwek
Glycosylation and prion protein.
Current opinion in structural biology 2002;12(5):578-86.
2002: Mylvaganam Jeyakumar; Terry D Butters; Raymond A Dwek; Frances M Platt
Glycosphingolipid lysosomal storage diseases: therapy and pathogenesis.
Neuropathology and applied neurobiology 2002;28(5):343-57.
2002: Anand Mehta; Serguey Ouzounov; Robert Jordan; Ender Simsek; Xuanyong Lu; Robert M Moriarty; Gary Jacob; Raymond A Dwek; Timothy M Block
Imino sugars that are less toxic but more potent as antivirals, in vitro, compared with N-n-nonyl DNJ.
Antiviral chemistry & chemotherapy 2002;13(5):299-304.
2002: Serguey Ouzounov; Anand Mehta; Raymond A Dwek; Timothy M Block; Robert Jordan
The combination of interferon alpha-2b and n-butyl deoxynojirimycin has a greater than additive antiviral effect upon production of infectious bovine viral diarrhea virus (BVDV) in vitro: implications for hepatitis C virus (HCV) therapy.
Antiviral research 2002;55(3):425-35.
2002: Norica Branza-Nichita; Catalin Lazar; David Durantel; Raymond A Dwek; Nicole Zitzmann
Role of disulfide bond formation in the folding and assembly of the envelope glycoproteins of a pestivirus.
Biochemical and biophysical research communications 2002;296(2):470-6.
2002: Howard R Mellor; James Nolan; Lea Pickering; Mark R Wormald; Frances M Platt; Raymond A Dwek; George W J Fleet; Terry D Butters
Preparation, biochemical characterization and biological properties of radiolabelled N-alkylated deoxynojirimycins.
The Biochemical journal 2002;366(Pt 1):225-33.
2002: Mylvaganam Jeyakumar; David Smith; Elena Eliott-Smith; Mario Cortina Borja; Gabriele Reinkensmeier; Terry D Butters; Thorsten Lemm; Konrad Sandhoff; V Hugh Perry; Raymond A Dwek; Frances M Platt
An inducible mouse model of late onset Tay-Sachs disease.
Neurobiology of disease 2002;10(3):201-10.
2002: Christopher N Scanlan; Ralph Pantophlet; Mark R Wormald; Erica Ollmann Saphire; Robyn L Stanfield; Ian A Wilson; Hermann Katinger; Raymond A Dwek; Pauline M Rudd; Dennis R Burton
The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.
Journal of virology 2002;76(14):7306-21.
2002: Erica Ollmann Saphire; Robyn L Stanfield; Max Crispin; Paul W H I Parren; Pauline M Rudd; Raymond A Dwek; Dennis R Burton; Ian A Wilson
Contrasting IgG structures reveal extreme asymmetry and flexibility.
Journal of molecular biology 2002;319(1):9-18.
2002: Gertrude-E Costin; Mihaela Trif; Norica Nichita; Raymond A Dwek; Stefana M Petrescu
pH-sensitive liposomes are efficient carriers for endoplasmic reticulum-targeted drugs in mouse melanoma cells.
Biochemical and biophysical research communications 2002;293(3):918-23.
2002: Anthony H Merry; David C A Neville; Louise Royle; Brian Matthews; David Harvey; Raymond A Dwek; Pauline M Rudd
Recovery of intact 2-aminobenzamide-labeled O-glycans released from glycoproteins by hydrazinolysis.
Analytical biochemistry 2002;304(1):91-9.
2002: Louise Royle; Taj S Mattu; Edmund Hart; James I Langridge; Anthony H Merry; Neil Murphy; David Harvey; Raymond A Dwek; Pauline M Rudd
An analytical and structural database provides a strategy for sequencing O-glycans from microgram quantities of glycoproteins.
Analytical biochemistry 2002;304(1):70-90.
2002: Susan F Wheeler; Pauline M Rudd; Simon J Davis; Raymond A Dwek; David Harvey
Comparison of the N-linked glycans from soluble and GPI-anchored CD59 expressed in CHO cells.
Glycobiology 2002;12(4):261-71.
2002: Shu-Fen Wu; Chyan-Jang Lee; Ching-Len Liao; Raymond A Dwek; Nicole Zitzmann; Yi-Ling Lin
Antiviral effects of an iminosugar derivative on flavivirus infections.
Journal of virology 2002;76(8):3596-604.
2002: Robert Jordan; Olga V Nikolaeva; Lijuan Wang; Bertha Conyers; Anand Mehta; Raymond A Dwek; Timothy M Block
Inhibition of host ER glucosidase activity prevents Golgi processing of virion-associated bovine viral diarrhea virus E2 glycoproteins and reduces infectivity of secreted virions.
Virology 2002;295(1):10-9.
2002: Bergljot Magnadottir; Max Crispin; Louise Royle; Cristina Colominas; David Harvey; Raymond A Dwek; Pauline M Rudd
The carbohydrate moiety of serum IgM from Atlantic cod (Gadus morhua L.).
Fish & shellfish immunology 2002;12(3):209-27.
2002: Eric E O'Neill; Chris J Brock; Alexander F von Kriegsheim; Andrew C Pearce; Raymond A Dwek; Steve P Watson; Holger F Hebestreit
Towards complete analysis of the platelet proteome.
Proteomics 2002;2(3):288-305.
2002: David Harvey; Taj S Mattu; Mark R Wormald; Louise Royle; Raymond A Dwek; Pauline M Rudd
"Internal residue loss": rearrangements occurring during the fragmentation of carbohydrates derivatized at the reducing terminus.
Analytical chemistry 2002;74(4):734-40.
2002: Brett Garner; Howard R Mellor; Terry D Butters; Raymond A Dwek; Frances M Platt
Modulation of THP-1 macrophage and cholesterol-loaded foam cell apolipoprotein E levels by glycosphingolipids.
Biochemical and biophysical research communications 2002;290(5):1361-7.
2002: Mark R Wormald; Andrei J Petrescu; Ya-Lan Pao; Ann Glithero; Tim Elliott; Raymond A Dwek
Conformational studies of oligosaccharides and glycopeptides: complementarity of NMR, X-ray crystallography, and molecular modelling.
Chemical reviews 2002;102(2):371-86.
2002: Gayle E Ritchie; Beryl E Moffatt; Robert B Sim; B Paul Morgan; Raymond A Dwek; Pauline M Rudd
Glycosylation and the complement system.
Chemical reviews 2002;102(2):305-20-19.
2002: Raymond A Dwek; Terry D Butters; Frances M Platt; Nicole Zitzmann
Targeting glycosylation as a therapeutic approach.
Nature reviews. Drug discovery 2002;1(1):65-75.
2002: Maren von Der Ohe; Susan F Wheeler; Manfred Wuhrer; David Harvey; Steffen Liedtke; Martina Mühlenhoff; Rita Gerardy-Schahn; Hildegard Geyer; Raymond A Dwek; Rudolf Geyer; David R Wing; Melitta Schachner
Localization and characterization of polysialic acid-containing N-linked glycans from bovine NCAM.
Glycobiology 2002;12(1):47-63.
2001: D R Wing; Brett Garner; V Hunnam; Gabriele Reinkensmeier; Ulrika Andersson; David Harvey; Raymond A Dwek; Frances M Platt; Terry D Butters
High-performance liquid chromatography analysis of ganglioside carbohydrates at the picomole level after ceramide glycanase digestion and fluorescent labeling with 2-aminobenzamide.
Analytical biochemistry 2001;298(2):207-17.
2001: X Lu; Y Lu; R Geschwindt; Raymond A Dwek; Timothy M Block
Hepatitis B virus MHBs antigen is selectively sensitive to glucosidase-mediated processing in the endoplasmic reticulum.
DNA and cell biology 2001;20(10):647-56.
2001: David Durantel; Norica Branza-Nichita; Sandra Carrouée-Durantel; Terry D Butters; Raymond A Dwek; Nicole Zitzmann
Study of the mechanism of antiviral action of iminosugar derivatives against bovine viral diarrhea virus.
Journal of virology 2001;75(19):8987-98.
2001: Erica Ollmann Saphire; Paul W H I Parren; Ralph Pantophlet; Michael B Zwick; G M Morris; Pauline M Rudd; Raymond A Dwek; Robyn L Stanfield; Dennis R Burton; Ian A Wilson
Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design.
Science (New York, N.Y.) 2001;293(5532):1155-9.
2001: Susanne Zamze; DR Wing; Mark R Wormald; AP Hunter; Raymond A Dwek; David Harvey
A family of novel, acidic N-glycans in Bowes melanoma tissue plasminogen activator have L2/HNK-1-bearing antennae, many with sulfation of the fucosylated chitobiose core.
European journal of biochemistry / FEBS 2001;268(14):4063-78.
2001: Anand Mehta; S Carrouée; Bertha Conyers; Robert Jordan; Terry D Butters; Raymond A Dwek; Timothy M Block
Inhibition of hepatitis B virus DNA replication by imino sugars without the inhibition of the DNA polymerase: therapeutic implications.
Hepatology (Baltimore, Md.) 2001;33(6):1488-95.
2001: Pauline M Rudd; Mark R Wormald; D R Wing; Stanley B Prusiner; Raymond A Dwek
Prion glycoprotein: structure, dynamics, and roles for the sugars.
Biochemistry 2001;40(13):3759-66.
2001: Frances M Platt; Mylvaganam Jeyakumar; Ulrika Andersson; David A Priestman; Raymond A Dwek; Terry D Butters; Timothy M Cox; Robin H Lachmann; Carla E M Hollak; johannes aerts; Sonja van Weely; M Hrebícek; C Moyses; I Gow; Deborah Elstein; Ari Zimran
Inhibition of substrate synthesis as a strategy for glycolipid lysosomal storage disease therapy.
Journal of inherited metabolic disease 2001;24(2):275-90.
2001: Norica Branza-Nichita; David Durantel; Sandra Carrouée-Durantel; Raymond A Dwek; Nicole Zitzmann
Antiviral effect of N-butyldeoxynojirimycin against bovine viral diarrhea virus correlates with misfolding of E2 envelope proteins and impairment of their association into E1-E2 heterodimers.
Journal of virology 2001;75(8):3527-36.
2001: Pauline M Rudd; Tim Elliott; Peter Cresswell; Ian A Wilson; Raymond A Dwek
Glycosylation and the immune system.
Science (New York, N.Y.) 2001;291(5512):2370-6.
2001: Malin Svensson; F Platt; B Frendeus; Terry D Butters; Raymond A Dwek; Catharina Svanborg
Carbohydrate receptor depletion as an antimicrobial strategy for prevention of urinary tract infection.
The Journal of infectious diseases 2001;183 Suppl 1():S70-3.
2001: Pauline M Rudd; Cristina Colominas; Louise Royle; N Murphy; Edmund Hart; Anthony H Merry; Holger F Hebestreit; Raymond A Dwek
A high-performance liquid chromatography based strategy for rapid, sensitive sequencing of N-linked oligosaccharide modifications to proteins in sodium dodecyl sulphate polyacrylamide electrophoresis gel bands.
Proteomics 2001;1(2):285-94.
2001: A Mehta; X Lu; Timothy M Block; A Willis; Raymond A Dwek; B Tennant; Baruch S Blumberg
Synovial stimulatory protein fragments copurify with woodchuck hepatitis virus: implications for the etiology of arthritis in chronic hepatitis B virus infection.
Arthritis and rheumatism 2001;44(2):486-7.
2001: Laura F Steel; Taj S Mattu; Anand Mehta; Holger F Hebestreit; Raymond A Dwek; Alison A Evans; W Thomas London; Timothy M Block
A proteomic approach for the discovery of early detection markers of hepatocellular carcinoma.
Disease markers 2001;17(3):179-89.
2001: Mylvaganam Jeyakumar; F Norflus; Cynthia J Tifft; Mario Cortina Borja; Terry D Butters; Richard L Proia; V Hugh Perry; Raymond A Dwek; Frances M Platt
Enhanced survival in Sandhoff disease mice receiving a combination of substrate deprivation therapy and bone marrow transplantation.
Blood 2001;97(1):327-9.
2000: Taj S Mattu; Louise Royle; J Langridge; Mark R Wormald; Philippe E Van den Steen; Jo Van Damme; Ghislain Opdenakker; David Harvey; Raymond A Dwek; Pauline M Rudd
O-glycan analysis of natural human neutrophil gelatinase B using a combination of normal phase-HPLC and online tandem mass spectrometry: implications for the domain organization of the enzyme.
Biochemistry 2000;39(51):15695-704.
2000: David A Priestman; Frances M Platt; Raymond A Dwek; Terry D Butters
Imino sugar therapy for type 1 Gaucher disease.
Glycobiology 2000;10(11):iv-vi.
2000: Gabriela Negroiu; Raymond A Dwek; Stefana M Petrescu
Folding and maturation of tyrosinase-related protein-1 are regulated by the post-translational formation of disulfide bonds and by N-glycan processing.
The Journal of biological chemistry 2000;275(41):32200-7.
2000: Howard R Mellor; A Adam; Frances M Platt; Raymond A Dwek; Terry D Butters
High-performance cation-exchange chromatography and pulsed amperometric detection for the separation, detection, and quantitation of N-alkylated imino sugars in biological samples.
Analytical biochemistry 2000;284(1):136-42.
2000: Stefana M Petrescu; Norica Branza-Nichita; Gabriela Negroiu; Andrei J Petrescu; Raymond A Dwek
Tyrosinase and glycoprotein folding: roles of chaperones that recognize glycans.
Biochemistry 2000;39(18):5229-37.
2000: T Cox; Robin H Lachmann; Carla E M Hollak; johannes aerts; Sonja van Weely; M Hrebícek; Frances M Platt; Terry D Butters; Raymond A Dwek; C Moyses; I Gow; Deborah Elstein; Ari Zimran
Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis.
Lancet 2000;355(9214):1481-5.
2000: Ulrika Andersson; Terry D Butters; Raymond A Dwek; Frances M Platt
N-butyldeoxygalactonojirimycin: a more selective inhibitor of glycosphingolipid biosynthesis than N-butyldeoxynojirimycin, in vitro and in vivo.
Biochemical pharmacology 2000;59(7):821-9.
2000: Norica Branza-Nichita; Gabriela Negroiu; Andrei J Petrescu; E F Garman; Frances M Platt; Mark R Wormald; Raymond A Dwek; Stefana M Petrescu
Mutations at critical N-glycosylation sites reduce tyrosinase activity by altering folding and quality control.
The Journal of biological chemistry 2000;275(11):8169-75.
2000: Pauline M Rudd; A Kristina Downing; Martine Cadene; David Harvey; Mark R Wormald; I Weir; Raymond A Dwek; Daniel B Rifkin; Pierre-Emmanuel Gleizes
Hybrid and complex glycans are linked to the conserved N-glycosylation site of the third eight-cysteine domain of LTBP-1 in insect cells.
Biochemistry 2000;39(7):1596-603.
1999: Gabriela Negroiu; Norica Branza-Nichita; Andrei J Petrescu; Raymond A Dwek; Stefana M Petrescu
Protein specific N-glycosylation of tyrosinase and tyrosinase-related protein-1 in B16 mouse melanoma cells.
The Biochemical journal 1999;344 Pt 3():659-65.
1999: Luisa Martínez-Pomares; Paul R Crocker; R Da Silva; N Holmes; Cristina Colominas; Pauline Rudd; Raymond A Dwek; Siamon Gordon
Cell-specific glycoforms of sialoadhesin and CD45 are counter-receptors for the cysteine-rich domain of the mannose receptor.
The Journal of biological chemistry 1999;274(49):35211-8.
1999: M Devasahayam; P D Catalino; Pauline M Rudd; Raymond A Dwek; A Neil Barclay
The glycan processing and site occupancy of recombinant Thy-1 is markedly affected by the presence of a glycosylphosphatidylinositol anchor.
Glycobiology 1999;9(12):1381-7.
1999: Pauline M Rudd; T Endo; Cristina Colominas; Darlene Groth; Susan F Wheeler; David Harvey; Mark R Wormald; Hana Serban; Stanley B Prusiner; Akira Kobata; Raymond A Dwek
Glycosylation differences between the normal and pathogenic prion protein isoforms.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13044-9.
1999: Gabriela Negroiu; Norica Branza-Nichita; Gertrude-E Costin; H Titu; Andrei J Petrescu; Raymond A Dwek; Stefana M Petrescu
Investigation of the intracellular transport of tyrosinase and tyrosinase related protein (TRP)-1. The effect of endoplasmic reticulum (ER)-glucosidases inhibition.
Cellular and molecular biology (Noisy-le-Grand, France) 1999;45(7):1001-10.
1999: Pauline M Rudd; Mark R Wormald; Robyn L Stanfield; M Huang; N Mattsson; Jeffrey A Speir; J A DiGennaro; Jacquelyn S Fetrow; Raymond A Dwek; Ian A Wilson
Roles for glycosylation of cell surface receptors involved in cellular immune recognition.
Journal of molecular biology 1999;293(2):351-66.
1999: Pauline M Rudd; Taj S Mattu; S Masure; T Bratt; Philippe E Van den Steen; Mark R Wormald; B Küster; David Harvey; Niels Borregaard; Jo Van Damme; Raymond A Dwek; Ghislain Opdenakker
Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin.
Biochemistry 1999;38(42):13937-50.
1999: Nicole Zitzmann; Anand S Mehta; S Carrouée; Terry D Butters; Frances M Platt; J McCauley; Baruch S Blumberg; Raymond A Dwek; Timothy M Block
Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: implications for the development of broad spectrum anti-hepatitis virus agents.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(21):11878-82.
1999: Norica Branza-Nichita; Andrei J Petrescu; Raymond A Dwek; Mark R Wormald; Frances M Platt; Stefana M Petrescu
Tyrosinase folding and copper loading in vivo: a crucial role for calnexin and alpha-glucosidase II.
Biochemical and biophysical research communications 1999;261(3):720-5.
1999: R A Clark; B Küster; M Benallal; B M Anner; Raymond A Dwek; David Harvey; D R Wing
Characterisation of tissue-specific oligosaccharides from rat brain and kidney membrane preparations enriched in Na+,K+-ATPase.
Glycoconjugate journal 1999;16(8):437-56.
1999: Susanne Zamze; David Harvey; P Pesheva; Taj S Mattu; M Schachner; Raymond A Dwek; DR Wing
Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and "brain-type" neutral N-glycans.
Glycobiology 1999;9(8):823-31.
1999: M R Wormald; Raymond A Dwek
Glycoproteins: glycan presentation and protein-fold stability.
Structure (London, England : 1993) 1999;7(7):R155-60.
1999: Mylvaganam Jeyakumar; Terry D Butters; Mario Cortina Borja; V Hunnam; Richard L Proia; V Hugh Perry; Raymond A Dwek; Frances M Platt
Delayed symptom onset and increased life expectancy in Sandhoff disease mice treated with N-butyldeoxynojirimycin.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(11):6388-93.
1999: Pauline M Rudd; Mark R Wormald; David Harvey; M Devasahayam; Mark S B McAlister; Marion H Brown; Simon J Davis; A Neil Barclay; Raymond A Dwek
Oligosaccharide analysis and molecular modeling of soluble forms of glycoproteins belonging to the Ly-6, scavenger receptor, and immunoglobulin superfamilies expressed in Chinese hamster ovary cells.
Glycobiology 1999;9(5):443-58.
1999: Andrei J Petrescu; Stefana M Petrescu; Raymond A Dwek; Mark R Wormald
A statistical analysis of N- and O-glycan linkage conformations from crystallographic data.
Glycobiology 1999;9(4):343-52.
1999: Pauline M Rudd; Taj S Mattu; Nicole Zitzmann; A Mehta; Cristina Colominas; Edmund Hart; Ghislain Opdenakker; Raymond A Dwek
Glycoproteins: rapid sequencing technology for N-linked and GPI anchor glycans.
Biotechnology & genetic engineering reviews 1999;16():1-21.
1999: Ann Glithero; Jose Tormo; JS Haurum; Gemma Arsequell; Gregorio Valencia; J Edwards; Sebastian Springer; A Townsend; Y L Pao; Mark R Wormald; Raymond A Dwek; E Yvonne Jones; Tim Elliott
Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity.
Immunity 1999;10(1):63-74.
1998: GR Guile; David Harvey; N O'Donnell; A K Powell; AP Hunter; Susanne Zamze; Daryl Fernandes; Raymond A Dwek; DR Wing
Identification of highly fucosylated N-linked oligosaccharides from the human parotid gland.
European journal of biochemistry / FEBS 1998;258(2):623-56.
1998: Robert J Woods; A Pathiaseril; Mark R Wormald; C J Edge; Raymond A Dwek
The high degree of internal flexibility observed for an oligomannose oligosaccharide does not alter the overall topology of the molecule.
European journal of biochemistry / FEBS 1998;258(2):372-86.
1998: Philippe E Van den Steen; Pauline M Rudd; Paul Proost; Erik Martens; L Paemen; B Küster; Jo Van Damme; Raymond A Dwek; Ghislain Opdenakker
Oligosaccharides of recombinant mouse gelatinase B variants.
Biochimica et biophysica acta 1998;1425(3):587-98.
1998: Susanne Zamze; David Harvey; Y J Chen; GR Guile; Raymond A Dwek; DR Wing
Sialylated N-glycans in adult rat brain tissue--a widespread distribution of disialylated antennae in complex and hybrid structures.
European journal of biochemistry / FEBS 1998;258(1):243-70.
1998: Mark S B McAlister; Marion H Brown; A C Willis; Pauline M Rudd; David Harvey; R Aplin; DM Shotton; Raymond A Dwek; A Neil Barclay; Paul C Driscoll
Structural analysis of the CD5 antigen--expression, disulphide bond analysis and physical characterisation of CD5 scavenger receptor superfamily domain 1.
European journal of biochemistry / FEBS 1998;257(1):131-41.
1998: B Küster; AP Hunter; Susan F Wheeler; Raymond A Dwek; David Harvey
Structural determination of N-linked carbohydrates by matrix-assisted laser desorption/ionization-mass spectrometry following enzymatic release within sodium dodecyl sulphate-polyacrylamide electrophoresis gels: application to species-specific glycosylation of alpha1-acid glycoprotein.
Electrophoresis 1998;19(11):1950-9.
1998: Pauline M Rudd; Mark R Wormald; Raymond A Dwek
Glycosylation and the immune system.
Journal of protein chemistry 1998;17(6):519.
1998: A Mehta; Nicole Zitzmann; Pauline M Rudd; Timothy M Block; Raymond A Dwek
Alpha-glucosidase inhibitors as potential broad based anti-viral agents.
FEBS letters 1998;430(1-2):17-22.
1998: R A Clark; James W Gurd; Nankie Bissoon; N Tricaud; Elek Molnar; Susanne Zamze; Raymond A Dwek; R A Jeffrey McIlhinney; DR Wing
Identification of lectin-purified neural glycoproteins, GPs 180, 116, and 110, with NMDA and AMPA receptor subunits: conservation of glycosylation at the synapse.
Journal of neurochemistry 1998;70(6):2594-605.
1998: Timothy M Block; Xuanyong Lu; Anand S Mehta; Baruch S Blumberg; Bud C Tennant; M Ebling; Brent E Korba; D M Lansky; G S Jacob; Raymond A Dwek
Treatment of chronic hepadnavirus infection in a woodchuck animal model with an inhibitor of protein folding and trafficking.
Nature medicine 1998;4(5):610-4.
1998: Y J Chen; DR Wing; GR Guile; Raymond A Dwek; David Harvey; Susanne Zamze
Neutral N-glycans in adult rat brain tissue--complete characterisation reveals fucosylated hybrid and complex structures.
European journal of biochemistry / FEBS 1998;251(3):691-703.
1998: Taj S Mattu; Richard J Pleass; Antony C Willis; M Kilian; Mark R Wormald; A C Lellouch; Pauline M Rudd; Jenny M Woof; Raymond A Dwek
The glycosylation and structure of human serum IgA1, Fab, and Fc regions and the role of N-glycosylation on Fc alpha receptor interactions.
The Journal of biological chemistry 1998;273(4):2260-72.
1998: Raymond A Dwek
Biological importance of glycosylation.
Developments in biological standardization 1998;96():43-7.
1998: Philippe E Van den Steen; Pauline M Rudd; Raymond A Dwek; Ghislain Opdenakker
Concepts and principles of O-linked glycosylation.
Critical reviews in biochemistry and molecular biology 1998;33(3):151-208.
1998: Timothy M Block; X Lu; A Mehta; J Park; Baruch S Blumberg; Raymond A Dwek
Role of glycan processing in hepatitis B virus envelope protein trafficking.
Advances in experimental medicine and biology 1998;435():207-16.
1998: A Mehta; Timothy M Block; Raymond A Dwek
The role of N-linked glycosylation in the secretion of hepatitis B virus.
Advances in experimental medicine and biology 1998;435():195-205.
1998: Pauline M Rudd; B Paul Morgan; Mark R Wormald; David Harvey; CW van den Berg; Simon J Davis; MA Ferguson; Raymond A Dwek
The glycosylation of the complement regulatory protein, human erythrocyte CD59.
Advances in experimental medicine and biology 1998;435():153-62.
1998: Philippe E Van den Steen; Pauline M Rudd; Raymond A Dwek; Jo Van Damme; Ghislain Opdenakker
Cytokine and protease glycosylation as a regulatory mechanism in inflammation and autoimmunity.
Advances in experimental medicine and biology 1998;435():133-43.
1997: A Mehta; Pauline M Rudd; Timothy M Block; Raymond A Dwek
A strategy for anti-viral intervention: the use of alpha-glucosidase inhibitors to prevent chaperone-mediated folding of viral envelope glycoproteins.
Biochemical Society transactions 1997;25(4):1188-93.
1997: Pauline M Rudd; B Paul Morgan; Mark R Wormald; David Harvey; CW van den Berg; Simon J Davis; MA Ferguson; Raymond A Dwek
Roles for glycosylation in the anti-inflammatory molecule CD59.
Biochemical Society transactions 1997;25(4):1177-84.
1997: Frances M Platt; Gabriele Reinkensmeier; Raymond A Dwek; Terry D Butters
Extensive glycosphingolipid depletion in the liver and lymphoid organs of mice treated with N-butyldeoxynojirimycin.
The Journal of biological chemistry 1997;272(31):19365-72.
1997: Andrei J Petrescu; Terry D Butters; Gabriele Reinkensmeier; Stefana M Petrescu; Frances M Platt; Raymond A Dwek; Mark R Wormald
The solution NMR structure of glucosylated N-glycans involved in the early stages of glycoprotein biosynthesis and folding.
The EMBO journal 1997;16(14):4302-10.
1997: B Küster; Susan F Wheeler; AP Hunter; Raymond A Dwek; David Harvey
Sequencing of N-linked oligosaccharides directly from protein gels: in-gel deglycosylation followed by matrix-assisted laser desorption/ionization mass spectrometry and normal-phase high-performance liquid chromatography.
Analytical biochemistry 1997;250(1):82-101.
1997: Pauline M Rudd; G R Guile; B Küster; David Harvey; G Opdenakker; Raymond A Dwek
Oligosaccharide sequencing technology.
Nature 1997;388(6638):205-7.
1997: Stefana M Petrescu; Andrei J Petrescu; H N Titu; Raymond A Dwek; Frances M Platt
Inhibition of N-glycan processing in B16 melanoma cells results in inactivation of tyrosinase but does not prevent its transport to the melanosome.
The Journal of biological chemistry 1997;272(25):15796-803.
1997: Frances M Platt; G R Neises; Gabriele Reinkensmeier; MJ Townsend; V Hugh Perry; Richard L Proia; B Winchester; Raymond A Dwek; Terry D Butters
Prevention of lysosomal storage in Tay-Sachs mice treated with N-butyldeoxynojirimycin.
Science (New York, N.Y.) 1997;276(5311):428-31.
1997: X Lu; A Mehta; M Dadmarz; Raymond A Dwek; Baruch S Blumberg; Timothy M Block
Aberrant trafficking of hepatitis B virus glycoproteins in cells in which N-glycan processing is inhibited.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2380-5.
1997: Pauline M Rudd; B Paul Morgan; Mark R Wormald; David Harvey; CW van den Berg; Simon J Davis; MA Ferguson; Raymond A Dwek
The glycosylation of the complement regulatory protein, human erythrocyte CD59.
The Journal of biological chemistry 1997;272(11):7229-44.
1997: A Mehta; X Lu; Timothy M Block; Baruch S Blumberg; Raymond A Dwek
Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: evidence that alteration of a single N-linked glycosylation site can regulate HBV secretion.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(5):1822-7.
1997: S Y Mir-Shekari; D A Ashford; David Harvey; Raymond A Dwek; I T Schulze
The glycosylation of the influenza A virus hemagglutinin by mammalian cells. A site-specific study.
The Journal of biological chemistry 1997;272(7):4027-36.
1997: Mark R Wormald; Pauline M Rudd; David Harvey; S C Chang; Ian G Scragg; Raymond A Dwek
Variations in oligosaccharide-protein interactions in immunoglobulin G determine the site-specific glycosylation profiles and modulate the dynamic motion of the Fc oligosaccharides.
Biochemistry 1997;36(6):1370-80.
1997: Pauline M Rudd; Raymond A Dwek
Glycosylation: heterogeneity and the 3D structure of proteins.
Critical reviews in biochemistry and molecular biology 1997;32(1):1-100.
1996: Oleg Iourin; Taj S Mattu; Nasi Mian; Geoffrey Keir; Bryan Winchester; Raymond A Dwek; Pauline M Rudd
The identification of abnormal glycoforms of serum transferrin in carbohydrate deficient glycoprotein syndrome type I by capillary zone electrophoresis.
Glycoconjugate journal 1996;13(6):1031-42.
1996: P B Fischer; G B Karlsson; Raymond A Dwek; Frances M Platt
N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with impaired gp120 shedding and gp41 exposure.
Journal of virology 1996;70(10):7153-60.
1996: P B Fischer; G B Karlsson; Terry D Butters; Raymond A Dwek; Frances M Platt
N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with changes in antibody recognition of the V1/V2 region of gp120.
Journal of virology 1996;70(10):7143-52.
1996: G R Guile; Pauline M Rudd; DR Wing; S B Prime; Raymond A Dwek
A rapid high-resolution high-performance liquid chromatographic method for separating glycan mixtures and analyzing oligosaccharide profiles.
Analytical biochemistry 1996;240(2):210-26.
1996: A J Jaques; G Opdenakker; T W Rademacher; Raymond A Dwek; Susanne Zamze
The glycosylation of Bowes melanoma tissue plasminogen activator: lectin mapping, reaction with anti-L2/HNK-1 antibodies and the presence of sulphated/glucuronic acid containing glycans.
The Biochemical journal 1996;316 ( Pt 2)():427-37.
1996: A Youings; S C Chang; Raymond A Dwek; Ian G Scragg
Site-specific glycosylation of human immunoglobulin G is altered in four rheumatoid arthritis patients.
The Biochemical journal 1996;314 ( Pt 2)():621-30.
1996: Y L Pao; M R Wormarld; Raymond A Dwek; A C Lellouch
Effect of serine O-glycosylation on cis-trans proline isomerization.
Biochemical and biophysical research communications 1996;219(1):157-62.
1995: JS Haurum; L Tan; Gemma Arsequell; P Frodsham; A C Lellouch; P A Moss; Raymond A Dwek; Andrew J McMichael; Tim Elliott
Peptide anchor residue glycosylation: effect on class I major histocompatibility complex binding and cytotoxic T lymphocyte recognition.
European journal of immunology 1995;25(12):3270-6.
1995: Raymond A Dwek; A C Lellouch; Mark R Wormald
Glycobiology: 'the function of sugar in the IgG molecule'.
Journal of anatomy 1995;187 ( Pt 2)():279-92.
1995: Raymond A Dwek
Glycobiology: more functions for oligosaccharides.
Science (New York, N.Y.) 1995;269(5228):1234-5.
1995: P B Fischer; M Collin; G B Karlsson; William James; Terry D Butters; Simon J Davis; Siamon Gordon; Raymond A Dwek; Frances M Platt
The alpha-glucosidase inhibitor N-butyldeoxynojirimycin inhibits human immunodeficiency virus entry at the level of post-CD4 binding.
Journal of virology 1995;69(9):5791-7.
1995: Pauline M Rudd; Robert J Woods; Mark R Wormald; Ghislain Opdenakker; A Kristina Downing; Iain D Campbell; Raymond A Dwek
The effects of variable glycosylation on the functional activities of ribonuclease, plasminogen and tissue plasminogen activator.
Biochimica et biophysica acta 1995;1248(1):1-10.
1995: G Opdenakker; Pauline M Rudd; Mark R Wormald; Raymond A Dwek; J Van Damme
Cells regulate the activities of cytokines by glycosylation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(5):453-7.
1995: R Malhotra; Mark R Wormald; Pauline M Rudd; P B Fischer; Raymond A Dwek; Robert B Sim
Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein.
Nature medicine 1995;1(3):237-43.
1995: K Mori; Raymond A Dwek; A Kristina Downing; Ghislain Opdenakker; Pauline M Rudd
The activation of type 1 and type 2 plasminogen by type I and type II tissue plasminogen activator.
The Journal of biological chemistry 1995;270(7):3261-7.
1995: Raymond A Dwek
Glycobiology: "towards understanding the function of sugars".
Biochemical Society transactions 1995;23(1):1-25.
1995: Simon J Davis; Elizabeth A Davies; A Neil Barclay; S Daenke; D L Bodian; E Yvonne Jones; David I Stuart; Terry D Butters; Raymond A Dwek; Philip van der Merwe
Ligand binding by the immunoglobulin superfamily recognition molecule CD2 is glycosylation-independent.
The Journal of biological chemistry 1995;270(1):369-75.
1995: P Rudd; F Fortune; T Lehner; R Parekh; T Patel; Mark R Wormald; R Malhotra; R Sim; Raymond A Dwek
Lectin-carbohydrate interactions in disease. T-cell recognition of IgA and IgD; mannose binding protein recognition of IgG0.
Advances in experimental medicine and biology 1995;376():147-52.
1994: Frances M Platt; G R Neises; G B Karlsson; Raymond A Dwek; Terry D Butters
N-butyldeoxygalactonojirimycin inhibits glycolipid biosynthesis but does not affect N-linked oligosaccharide processing.
The Journal of biological chemistry 1994;269(43):27108-14.
1994: G R Guile; S Y Wong; Raymond A Dwek
Analytical and preparative separation of anionic oligosaccharides by weak anion-exchange high-performance liquid chromatography on an inert polymer column.
Analytical biochemistry 1994;222(1):231-5.
1994: Pauline M Rudd; F Fortune; T Patel; R B Parekh; Raymond A Dwek; T Lehner
A human T-cell receptor recognizes 'O'-linked sugars from the hinge region of human IgA1 and IgD.
Immunology 1994;83(1):99-106.
1994: JS Haurum; Gemma Arsequell; A C Lellouch; S Y Wong; Raymond A Dwek; Andrew J McMichael; Tim Elliott
Recognition of carbohydrate by major histocompatibility complex class I-restricted, glycopeptide-specific cytotoxic T lymphocytes.
The Journal of experimental medicine 1994;180(2):739-44.
1994: Robert J Woods; C J Edge; Raymond A Dwek
Protein surface oligosaccharides and protein function.
Nature structural biology 1994;1(8):499-501.
1994: T W Rademacher; P Williams; Raymond A Dwek
Agalactosyl glycoforms of IgG autoantibodies are pathogenic.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):6123-7.
1994: S Y Wong; G R Guile; Raymond A Dwek; G Arsequell
Synthetic glycosylation of proteins using N-(beta-saccharide) iodoacetamides: applications in site-specific glycosylation and solid-phase enzymic oligosaccharide synthesis.
The Biochemical journal 1994;300 ( Pt 3)():843-50.
1994: Mark Field; S Amatayakul-Chantler; T W Rademacher; Pauline M Rudd; Raymond A Dwek
Structural analysis of the N-glycans from human immunoglobulin A1: comparison of normal human serum immunoglobulin A1 with that isolated from patients with rheumatoid arthritis.
The Biochemical journal 1994;299 ( Pt 1)():261-75.
1994: Frances M Platt; G R Neises; Raymond A Dwek; Terry D Butters
N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis.
The Journal of biological chemistry 1994;269(11):8362-5.
1994: Timothy M Block; X Lu; Frances M Platt; G R Foster; W H Gerlich; Baruch S Blumberg; Raymond A Dwek
Secretion of human hepatitis B virus is inhibited by the imino sugar N-butyldeoxynojirimycin.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2235-9.
1994: Peter Arkwright; T W Rademacher; F Boutignon; Raymond A Dwek; C W G Redman
Suppression of allogeneic reactivity in vitro by the syncytiotrophoblast membrane glycocalyx of the human term placenta is carbohydrate dependent.
Glycobiology 1994;4(1):39-47.
1994: Pauline M Rudd; H C Joao; E Coghill; P Fiten; M R Saunders; Ghislain Opdenakker; Raymond A Dwek
Glycoforms modify the dynamic stability and functional activity of an enzyme.
Biochemistry 1994;33(1):17-22.
1994: G Arsequell; Raymond A Dwek; S Y Wong
9-Fluorenylmethoxycarbonyl (Fmoc)-glycine coupling of saccharide beta-glycosylamines for the fractionation of oligosaccharides and the formation of neoglycoconjugates.
Analytical biochemistry 1994;216(1):165-70.
1993: S Y Wong; I D Manger; G R Guile; T W Rademacher; Raymond A Dwek
Analysis of carbohydrate-protein interactions with synthetic N-linked neoglycoconjugate probes.
The Biochemical journal 1993;296 ( Pt 3)():817-25.
1993: H C Joao; Raymond A Dwek
Effects of glycosylation on protein structure and dynamics in ribonuclease B and some of its individual glycoforms.
European journal of biochemistry / FEBS 1993;218(1):239-44.
1993: G Opdenakker; Pauline M Rudd; C P Ponting; Raymond A Dwek
Concepts and principles of glycobiology.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(14):1330-7.
1993: Raymond A Dwek; D A Ashford; C J Edge; R B Parekh; T W Rademacher; DR Wing; A Neil Barclay; Simon J Davis; A F Williams
Glycosylation of CD4 and Thy-1.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1993;342(1299):43-50.
1993: A F Williams; R B Parekh; DR Wing; Antony C Willis; A Neil Barclay; R Dalchau; J W Fabre; Raymond A Dwek; T W Rademacher
Comparative analysis of the N-glycans of rat, mouse and human Thy-1. Site-specific oligosaccharide patterns of neural Thy-1, a member of the immunoglobulin superfamily.
Glycobiology 1993;3(4):339-48.
1993: Peter Arkwright; T W Rademacher; Raymond A Dwek; C W G Redman
Pre-eclampsia is associated with an increase in trophoblast glycogen content and glycogen synthase activity, similar to that found in hydatidiform moles.
The Journal of clinical investigation 1993;91(6):2744-53.
1993: S Y Wong; G R Guile; T W Rademacher; Raymond A Dwek
Synthetic glycosylation of peptides using unprotected saccharide beta-glycosylamines.
Glycoconjugate journal 1993;10(3):227-34.
1993: S Amatayakul-Chantler; Raymond A Dwek; Glenys A Tennent; M B Pepys; T W Rademacher
Molecular characterization of Limulus polyphemus C-reactive protein. II. Asparagine-linked oligosaccharides.
European journal of biochemistry / FEBS 1993;214(1):99-110.
1993: D A Ashford; C D Alafi; V M Gamble; D J Mackay; T W Rademacher; P J Williams; Raymond A Dwek; A Neil Barclay; Simon J Davis; C Somoza
Site-specific glycosylation of recombinant rat and human soluble CD4 variants expressed in Chinese hamster ovary cells.
The Journal of biological chemistry 1993;268(5):3260-7.
1993: G B Karlsson; Terry D Butters; Raymond A Dwek; Frances M Platt
Effects of the imino sugar N-butyldeoxynojirimycin on the N-glycosylation of recombinant gp120.
The Journal of biological chemistry 1993;268(1):570-6.
1993: Raymond A Dwek; C J Edge; David Harvey; Mark R Wormald; R B Parekh
Analysis of glycoprotein-associated oligosaccharides.
Annual review of biochemistry 1993;62():65-100.
1992: DR Wing; T W Rademacher; Mark Field; Raymond A Dwek; B Schmitz; G Thor; M Schachner
Use of large-scale hydrazinolysis in the preparation of N-linked oligosaccharide libraries: application to brain tissue.
Glycoconjugate journal 1992;9(6):293-301.
1992: I D Manger; S Y Wong; T W Rademacher; Raymond A Dwek
Synthesis of 1-N-glycyl beta-oligosaccharide derivatives. Reactivity of Lens culinaris lectin with a fluorescent labeled streptavidin pseudoglycoprotein and immobilized neoglycolipid.
Biochemistry 1992;31(44):10733-40.
1992: I D Manger; T W Rademacher; Raymond A Dwek
1-N-glycyl beta-oligosaccharide derivatives as stable intermediates for the formation of glycoconjugate probes.
Biochemistry 1992;31(44):10724-32.
1992: H C Joao; Ian G Scragg; Raymond A Dwek
Effects of glycosylation on protein conformation and amide proton exchange rates in RNase B.
FEBS letters 1992;307(3):343-6.
1992: C J Edge; T W Rademacher; Mark R Wormald; R B Parekh; Terry D Butters; DR Wing; Raymond A Dwek
Fast sequencing of oligosaccharides: the reagent-array analysis method.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(14):6338-42.
1992: DR Wing; T W Rademacher; B Schmitz; M Schachner; Raymond A Dwek
Comparative glycosylation in neural adhesion molecules.
Biochemical Society transactions 1992;20(2):386-90.
1992: Pauline M Rudd; Ian G Scragg; E Coghill; Raymond A Dwek
Separation and analysis of the glycoform populations of ribonuclease B using capillary electrophoresis.
Glycoconjugate journal 1992;9(2):86-91.
1992: Mark Field; DR Wing; Raymond A Dwek; T W Rademacher; B Schmitz; E Bollensen; M Schachner
Detection of multisulphated N-linked glycans in the L2/HNK-1 carbohydrate epitope expressing neural adhesion molecule P0.
Journal of neurochemistry 1992;58(3):993-1000.
1991: N Sumar; C B Colaço; K B Bodman; R Parekh; P Williams; Raymond A Dwek; T Rademacher; David A Isenberg; A Soltys; Frank C Hay
Abnormalities in the glycosylation of IgG in spouses of patients with rheumatoid arthritis. A family study.
Journal of autoimmunity 1991;4(6):907-14.
1991: Mark R Wormald; C J Edge; Raymond A Dwek
The solution conformation of the Le chi group.
Biochemical and biophysical research communications 1991;180(3):1214-21.
1991: Peter Arkwright; C W G Redman; P J Williams; Raymond A Dwek; T W Rademacher
Syncytiotrophoblast membrane protein glycosylation patterns in normal human pregnancy and changes with gestational age and parturition.
Placenta 1991;12(6):637-51.
1991: Susanne Zamze; D A Ashford; E W Wooten; T W Rademacher; Raymond A Dwek
Structural characterization of the asparagine-linked oligosaccharides from Trypanosoma brucei type II and type III variant surface glycoproteins.
The Journal of biological chemistry 1991;266(30):20244-61.
1991: P J Williams; Mark R Wormald; Raymond A Dwek; T W Rademacher; G F Parker; D R Roberts
Characterisation of oligosaccharides from Drosophila melanogaster glycoproteins.
Biochimica et biophysica acta 1991;1075(2):146-53.
1991: D A Ashford; Raymond A Dwek; T W Rademacher; H Lis; N Sharon
The glycosylation of glycoprotein lectins. Intra- and inter-genus variation in N-linked oligosaccharide expression.
Carbohydrate research 1991;213():215-27.
1991: Mark R Wormald; E W Wooten; R Bazzo; C J Edge; A Feinstein; T W Rademacher; Raymond A Dwek
The conformational effects of N-glycosylation on the tailpiece from serum IgM.
European journal of biochemistry / FEBS 1991;198(1):131-9.
1990: P Scudder; D C Neville; Terry D Butters; George W J Fleet; Raymond A Dwek; T W Rademacher; Gary S Jacob
The isolation by ligand affinity chromatography of a novel form of alpha-L-fucosidase from almond.
The Journal of biological chemistry 1990;265(27):16472-7.
1990: Stephen J Perkins; K F Smith; S Amatayakul; D Ashford; T W Rademacher; Raymond A Dwek; Peter Lachmann; R A Harrison
Two-domain structure of the native and reactive centre cleaved forms of C1 inhibitor of human complement by neutron scattering.
Journal of molecular biology 1990;214(3):751-63.
1990: E W Wooten; C J Edge; R Bazzo; Raymond A Dwek; T W Rademacher
Uncertainties in structural determinations of oligosaccharide conformation, using measurements of nuclear Overhauser effects.
Carbohydrate research 1990;203(1):13-7.
1990: R W Olafson; J R Thomas; MA Ferguson; Raymond A Dwek; Minu Chaudhuri; Kwang-Poo Chang; T W Rademacher
Structures of the N-linked oligosaccharides of Gp63, the major surface glycoprotein, from Leishmania mexicana amazonensis.
The Journal of biological chemistry 1990;265(21):12240-7.
1990: N Sumar; K B Bodman; T W Rademacher; Raymond A Dwek; P Williams; R B Parekh; J Edge; Graham Rook; David A Isenberg; Frank C Hay
Analysis of glycosylation changes in IgG using lectins.
Journal of immunological methods 1990;131(1):127-36.
1990: J R Thomas; Raymond A Dwek; T W Rademacher
Structure, biosynthesis, and function of glycosylphosphatidylinositols.
Biochemistry 1990;29(23):5413-22.
1990: C J Edge; U C Singh; R Bazzo; G L Taylor; Raymond A Dwek; T W Rademacher
500-picosecond molecular dynamics in water of the Man alpha 1----2Man alpha glycosidic linkage present in Asn-linked oligomannose-type structures on glycoproteins.
Biochemistry 1990;29(8):1971-4.
1990: Susanne Zamze; E W Wooten; D A Ashford; MA Ferguson; Raymond A Dwek; T W Rademacher
Characterisation of the asparagine-linked oligosaccharides from Trypanosoma brucei type-I variant surface glycoproteins.
European journal of biochemistry / FEBS 1990;187(3):657-63.
1990: E W Wooten; R Bazzo; C J Edge; Susanne Zamze; Raymond A Dwek; T W Rademacher
Primary sequence dependence of conformation in oligomannose oligosaccharides.
European biophysics journal : EBJ 1990;18(3):139-48.
1989: Mark Field; Raymond A Dwek; C J Edge; T W Rademacher
O-linked oligosaccharides from human serum immunoglobulin A1.
Biochemical Society transactions 1989;17(6):1034-5.
1989: R B Parekh; Raymond A Dwek; Pauline M Rudd; J R Thomas; T W Rademacher; T Warren; T C Wun; B Hebert; B Reitz; M Palmier
N-glycosylation and in vitro enzymatic activity of human recombinant tissue plasminogen activator expressed in Chinese hamster ovary cells and a murine cell line.
Biochemistry 1989;28(19):7670-9.
1989: A J Wittwer; Carol Howard; L S Carr; N K Harakas; J Feder; R B Parekh; Pauline M Rudd; Raymond A Dwek; T W Rademacher
Effects of N-glycosylation on in vitro activity of Bowes melanoma and human colon fibroblast derived tissue plasminogen activator.
Biochemistry 1989;28(19):7662-9.
1989: R B Parekh; Raymond A Dwek; J R Thomas; Ghislain Opdenakker; T W Rademacher; A J Wittwer; Carol Howard; R Nelson; N R Siegel; M G Jennings
Cell-type-specific and site-specific N-glycosylation of type I and type II human tissue plasminogen activator.
Biochemistry 1989;28(19):7644-62.
1989: S W Homans; C J Edge; MA Ferguson; Raymond A Dwek; T W Rademacher
Solution structure of the glycosylphosphatidylinositol membrane anchor glycan of Trypanosoma brucei variant surface glycoprotein.
Biochemistry 1989;28(7):2881-7.
1989: R Parekh; D Isenberg; Graham Rook; I Roitt; Raymond A Dwek; T Rademacher
A comparative analysis of disease-associated changes in the galactosylation of serum IgG.
Journal of autoimmunity 1989;2(2):101-14.
1989: J S Axford; K Bodman; Frank C Hay; David A Isenberg; Peter M Lydyard; L Mackenzie; Ivan M Roitt; N Sumar; Graham Rook; Raymond A Dwek
Comment on the article by Tomana et al.
Arthritis and rheumatism 1989;32(2):235-6.
1989: T W Rademacher; Raymond A Dwek
The role of oligosaccharides in modifying protein function.
Ciba Foundation symposium 1989;145():241-55; discussion 255-6.
1988: A Karpas; George W J Fleet; Raymond A Dwek; S Petursson; S K Namgoong; N G Ramsden; Gary S Jacob; T W Rademacher
Aminosugar derivatives as potential anti-human immunodeficiency virus agents.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(23):9229-33.
1988: Susanne Zamze; MA Ferguson; R Collins; Raymond A Dwek; T W Rademacher
Characterization of the cross-reacting determinant (CRD) of the glycosyl-phosphatidylinositol membrane anchor of Trypanosoma brucei variant surface glycoprotein.
European journal of biochemistry / FEBS 1988;176(3):527-34.
1988: George W J Fleet; A Karpas; Raymond A Dwek; L E Fellows; A S Tyms; S Petursson; S K Namgoong; N G Ramsden; P W Smith; J C Son
Inhibition of HIV replication by amino-sugar derivatives.
FEBS letters 1988;237(1-2):128-32.
1988: D A Isenberg; Peter M Lydyard; J S Axford; Frank C Hay; Graham Rook; Ivan M Roitt; N Sumar; R B Parekh; Raymond A Dwek; T W Rademacher
Galactosylation of IgG associated oligosaccharides.
Lancet 1988;2(8605):288.
1988: Ivan M Roitt; Raymond A Dwek; R B Parekh; T W Rademacher; Azita Alavi; J Axford; K Bodman; Alyson Bond; A Cooke; Frank C Hay
Changes in carbohydrate structure of IgG in rheumatoid arthritis.
Recenti progressi in medicina 1988;79(7-8):314-7.
1988: MA Ferguson; S W Homans; Raymond A Dwek; T W Rademacher
The glycosylphosphatidylinositol membrane anchor of Trypanosoma brucei variant surface glycoprotein.
Biochemical Society transactions 1988;16(3):265-8.
1988: S W Homans; MA Ferguson; Raymond A Dwek; T W Rademacher; R Anand; A F Williams
Complete structure of the glycosyl phosphatidylinositol membrane anchor of rat brain Thy-1 glycoprotein.
Nature 1988;333(6170):269-72.
1988: R Parekh; I Roitt; D Isenberg; Raymond A Dwek; T Rademacher
Age-related galactosylation of the N-linked oligosaccharides of human serum IgG.
The Journal of experimental medicine 1988;167(5):1731-6.
1988: R B Parekh; I M Roitt; D A Isenberg; Raymond A Dwek; B M Ansell; T W Rademacher
Galactosylation of IgG associated oligosaccharides: reduction in patients with adult and juvenile onset rheumatoid arthritis and relation to disease activity.
Lancet 1988;1(8592):966-9.
1988: MA Ferguson; S W Homans; Raymond A Dwek; T W Rademacher
Glycosyl-phosphatidylinositol moiety that anchors Trypanosoma brucei variant surface glycoprotein to the membrane.
Science (New York, N.Y.) 1988;239(4841 Pt 1):753-9.
1988: T W Rademacher; R B Parekh; Raymond A Dwek
Glycobiology.
Annual review of biochemistry 1988;57():785-838.
1987: S W Homans; A Pastore; Raymond A Dwek; T W Rademacher
Structure and dynamics in oligomannose-type oligosaccharides.
Biochemistry 1987;26(21):6649-55.
1987: S W Homans; Raymond A Dwek; T W Rademacher
Solution conformations of N-linked oligosaccharides.
Biochemistry 1987;26(21):6571-8.
1987: S W Homans; Raymond A Dwek; T W Rademacher
Tertiary structure in N-linked oligosaccharides.
Biochemistry 1987;26(20):6553-60.
1987: D Ashford; Raymond A Dwek; J K Welply; S Amatayakul; S W Homans; H Lis; G N Taylor; N Sharon; T W Rademacher
The beta 1----2-D-xylose and alpha 1----3-L-fucose substituted N-linked oligosaccharides from Erythrina cristagalli lectin. Isolation, characterisation and comparison with other legume lectins.
European journal of biochemistry / FEBS 1987;166(2):311-20.
1987: Susanne Zamze; M A Ferguson; E R Moxon; Raymond A Dwek; T W Rademacher
Identification of phosphorylated 3-deoxy-manno-octulosonic acid as a component of Haemophilus influenzae lipopolysaccharide.
The Biochemical journal 1987;245(2):583-7.