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Martin Dyer

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Martin J S Dyer; Sandrine Jayne; Catrin Pritchard; Jesvin Samuel; Meike Vogler; Simon Wagner; Salvador Macip
Precision medicines for B-cell leukaemias and lymphomas; progress and potential pitfalls.
Martin J S Dyer
The detection of chromosomal translocations involving the immunoglobulin loci in B-cell malignancies.
Rocío Ramos-Medina; María Rodríguez-Pinilla; Marta Cañamero; Martin J S Dyer; Lorena Maestre; Aneela Majid; Jorge Martínez-Torrecuadrada; Santiago Montes-Moreno; Miguel Ángel Piris; Karen Pulford; Giovanna Roncador
BCL7A protein expression in normal and malignant lymphoid tissues.

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All Publications

2013: Martin J S Dyer; Sandrine Jayne; Catrin Pritchard; Jesvin Samuel; Meike Vogler; Simon Wagner; Salvador Macip
Precision medicines for B-cell leukaemias and lymphomas; progress and potential pitfalls.
British journal of haematology 2013;160(6):725-33.
2013: Martin J S Dyer
The detection of chromosomal translocations involving the immunoglobulin loci in B-cell malignancies.
Methods in molecular biology (Clifton, N.J.) 2013;971():123-33.
2013: Rocío Ramos-Medina; María Rodríguez-Pinilla; Marta Cañamero; Martin J S Dyer; Lorena Maestre; Aneela Majid; Jorge Martínez-Torrecuadrada; Santiago Montes-Moreno; Miguel Ángel Piris; Karen Pulford; Giovanna Roncador
BCL7A protein expression in normal and malignant lymphoid tissues.
British journal of haematology 2013;160(1):106-9.
2012: Stephen M Ansell; Esteban Braggio; James R Cerhan; Ahmet Dogan; Martin J S Dyer; Rafael Fonseca; Mamta Gupta; Mark Law; Michelle Manske; Ellen McPhail; Tammy Price-Troska; Frank Secreto; Thomas E Witzig; Steven C Ziesmer; Takashi Akasaka; Anne J Novak
t(X;14)(p11;q32) in MALT lymphoma involving GPR34 reveals a role for GPR34 in tumor cell growth.
Blood 2012;120(19):3949-57.
2012: Vicente Fresquet; Jesus M Hernandez-Rivas; Raquel Malumbres; Xabier Agirre; David Arteta; María J Calasanz; Susana Catarino; Masanori Daibata; Martin J S Dyer; Javier Martinez-Useros; Maria Mena; Manuela Mollejo; Lourdes Osaba; David Oscier; Anton Parker; Miguel-Ángel Piris; Felipe Prosper; Eloy Francisco Robles; Esperanza Vizcarra; Jose A Martinez-Climent
High-throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginal-zone lymphoma.
British journal of haematology 2012;158(6):712-26.
2012: Martin J S Dyer
Safety and efficacy of ofatumumab in patients with fludarabine and alemtuzumab refractory chronic lymphocytic leukaemia.
Therapeutic advances in hematology 2012;3(4):199-207.
2012: Itziar Salaverria; Monika Szczepanowski; Takashi Akasaka; Birgit Burkhardt; Christine Damm-Welk; Martin J S Dyer; Stefan Gesk; Lana Harder; Wolfram Klapper; Ilske Oschlies; Reiner Siebert
The CBFA2T3/ACSF3 locus is recurrently involved in IGH chromosomal translocation t(14;16)(q32;q24) in pediatric B-cell lymphoma with germinal center phenotype.
Genes, chromosomes & cancer 2012;51(4):338-43.
2012: Chris Pepper; Guy Pratt; Reiner Siebert; Ian Tracy; Simon Wagner; Renata Walewska; Paul Brennan; Zadie Davis; Martin J S Dyer; Anne C Gardiner; Stefan Gesk; Saman Hewamana; Robert K Hills; Ben Kennedy; Thet Thet Lin; Aneela Majid; Fiona Miall; David Oscier; Chris Fegan
Defining the prognosis of early stage chronic lymphocytic leukaemia patients.
British journal of haematology 2012;156(4):499-507.
2011: Padmaja Lokireddy; Martin J S Dyer
Bilateral subdural hygromas following intrathecal methotrexate.
British journal of haematology 2011;155(5):536.
2011: Anton B Alexandroff; W Mark Bamford; Robert Burd; D Ben J Kennedy; Volha Shpadaruk; Martin J S Dyer
Alemtuzumab-resistant Sézary syndrome responding to zanolimumab.
British journal of haematology 2011;154(3):419-21.
2011: Meike Vogler; Edward T W Bampton; David Dinsdale; Martin J S Dyer; Alison H Goodall; Hassan A Hamali; Roger T Snowden; Xiao-Ming Sun; Gerald M Cohen
BCL2/BCL-X(L) inhibition induces apoptosis, disrupts cellular calcium homeostasis, and prevents platelet activation.
Blood 2011;117(26):7145-54.
2011: Martin J S Dyer; Hongtao Ye; Peter G Isaacson
Primary lymphoma-like lesions of the uterine cervix; sheep in wolves' clothing.
British journal of haematology 2011;153(6):791-4.
2011: Aneela Majid; Fiona Miall; David G Oscier; Guy Pratt; Simon Wagner; Deborah Yallop; Giles Best; Andrea G S Buggins; Stephen Devereux; Martin J S Dyer; Chris Fegan; Keith Fishlock; Saman Hewamana; Robert Hills; Ben J Kennedy; Thet Thet Lin; Chris Pepper
CD49d is an independent prognostic marker that is associated with CXCR4 expression in CLL.
Leukemia research 2011;35(6):750-6.
2011: Meike Vogler; David Dickens; Martin J S Dyer; Andrew Owen; Munir Pirmohamed; Gerald M Cohen
The B-cell lymphoma 2 (BCL2)-inhibitors, ABT-737 and ABT-263, are substrates for P-glycoprotein.
Biochemical and biophysical research communications 2011;408(2):344-9.
2011: Aneela Majid; Tom Richards; Palminder Dusanjh; D Benjamin J Kennedy; Fiona Miall; Stefan Gesk; Reiner Siebert; Simon D Wagner; Martin J S Dyer
TP53 codon 72 polymorphism in patients with chronic lymphocytic leukaemia: identification of a subgroup with mutated IGHV genes and poor clinical outcome.
British journal of haematology 2011;153(4):533-5.
2011: Martin J S Dyer; Aneela Majid; Renata Walewska; Stefan Gesk; Lana Harder; Reiner Siebert; Bruno Morgan
Splenic infarction associated with rapidly progressive chronic lymphocytic leukemia with complex karyotype and ATM mutation.
Leukemia research 2011;35(5):e55-7.
2011: Melania Capasso; Thomas E DeCoursey; Martin J S Dyer
pH regulation and beyond: unanticipated functions for the voltage-gated proton channel, HVCN1.
Trends in cell biology 2011;21(1):20-8.
2010: Victoria J Weston; Ceri E Oldreive; Anna Skowronska; David Oscier; Guy Pratt; Martin J S Dyer; Graeme Smith; Judith E Powell; Zbigniew Rudzki; Pamela Kearns; Paul A H Moss; A Malcolm R Taylor; Tatjana Stankovic
The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.
Blood 2010;116(22):4578-87.
2010: Robert S Boyd; Martin J S Dyer; Kelvin Cain
Proteomic analysis of B-cell malignancies.
Journal of proteomics 2010;73(10):1804-22.
2010: Maria Baou; Susan L Kohlhaas; Michael Butterworth; Meike Vogler; David Dinsdale; Renata Walewska; Aneela Majid; Eric Eldering; Martin J S Dyer; Gerald M Cohen
Role of NOXA and its ubiquitination in proteasome inhibitor-induced apoptosis in chronic lymphocytic leukemia cells.
Haematologica 2010;95(9):1510-8.
2010: Inga Nagel; Monika Szczepanowski; José I Martín-Subero; Lana Harder; Takashi Akasaka; Ole Ammerpohl; Evelyne Callet-Bauchu; Randy D Gascoyne; Stefan Gesk; Doug Horsman; Wolfram Klapper; Aneela Majid; Jose A Martinez-Climent; Stephan Stilgenbauer; Holger Tönnies; Martin J S Dyer; Reiner Siebert
Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies.
Blood 2010;116(8):1317-20.
2010: Meike Vogler; Silviya D Furdas; Manfred Jung; Tomomi Kuwana; Martin J S Dyer; Gerald M Cohen
Diminished sensitivity of chronic lymphocytic leukemia cells to ABT-737 and ABT-263 due to albumin binding in blood.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(16):4217-25.
2010: Gunnar Cario; Martin Zimmermann; Renja Romey; Stefan Gesk; Inga Vater; Jochen Harbott; André Schrauder; Anja Moericke; Shai Izraeli; Takashi Akasaka; Martin J S Dyer; Reiner Siebert; Martin Schrappe; Martin Stanulla
Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol.
Blood 2010;115(26):5393-7.
2010: Ekkehard Mössner; Peter Brünker; Samuel Moser; Ursula Püntener; Carla Schmidt; Sylvia Herter; Roger Grau; Christian Gerdes; Adam Nopora; Erwin van Puijenbroek; Claudia Ferrara; Peter Sondermann; Christiane Jäger; Pamela Strein; Georg Fertig; Thomas Friess; Christine Schüll; Sabine Bauer; Joseph Dal Porto; Christopher Del Nagro; Karim Dabbagh; Martin J S Dyer; Sibrand Poppema; Christian Klein; Pablo Umaña
Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity.
Blood 2010;115(22):4393-402.
2010: Dalemari Crowther-Swanepoel; Peter Broderick; Yussanne Ma; Lindsay Robertson; Alan Pittman; Amy Price; Philip Twiss; Jayaram Vijayakrishnan; Mobshra Qureshi; Martin J S Dyer; Estella Matutes; Claire Dearden; Daniel Catovsky; richard Houlston
Fine-scale mapping of the 6p25.3 chronic lymphocytic leukaemia susceptibility locus.
Human molecular genetics 2010;19(9):1840-5.
2010: William G Wierda; Thomas J Kipps; Jirí Mayer; Stephan Stilgenbauer; Cathy D Williams; Andrzej Hellmann; Tadeusz Robak; Richard R Furman; Peter Hillmen; Marek Trneny; Martin J S Dyer; Swami Padmanabhan; Magdalena Piotrowska; Tomas Kozak; Geoffrey Chan; Randy Davis; Nedjad Losic; Joris Wilms; Charlotte A Russell; Anders Osterborg
Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(10):1749-55.
2010: Melania Capasso; Mandeep K Bhamrah; Tom Henley; Robert S Boyd; C Langlais; Kelvin Cain; David Dinsdale; Karen Pulford; Mahmood Khan; Boris Musset; Vladimir V Cherny; Deri Morgan; Randy D Gascoyne; Elena Vigorito; Thomas DeCoursey; Ian C M MacLennan; Martin J S Dyer
HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species.
Nature immunology 2010;11(3):265-72.
2010: Martin J S Dyer; Takashi Akasaka; Melania Capasso; Palminder Dusanjh; Yin-Fai Lee; E Loraine Karran; Inga Nagel; Inga Vater; Gunnar Cario; Reiner Siebert
Immunoglobulin heavy chain locus chromosomal translocations in B-cell precursor acute lymphoblastic leukemia: rare clinical curios or potent genetic drivers?
Blood 2010;115(8):1490-9.
2010: Boris Musset; Melania Capasso; Vladimir V Cherny; Deri Morgan; Mandeep Bhamrah; Martin J S Dyer; Thomas DeCoursey
Identification of Thr29 as a critical phosphorylation site that activates the human proton channel Hvcn1 in leukocytes.
The Journal of biological chemistry 2010;285(8):5117-21.
2009: Dalemari Crowther-Swanepoel; Mobshra Qureshi; Martin J S Dyer; Estella Matutes; Claire Dearden; Daniel Catovsky; richard Houlston
Genetic variation in CXCR4 and risk of chronic lymphocytic leukemia.
Blood 2009;114(23):4843-6.
2009: Satoshi Inoue; Nick Harper; Renata Walewska; Martin J S Dyer; Gerald M Cohen
Enhanced Fas-associated death domain recruitment by histone deacetylase inhibitors is critical for the sensitization of chronic lymphocytic leukemia cells to TRAIL-induced apoptosis.
Molecular cancer therapeutics 2009;8(11):3088-97.
2009: Deri Morgan; Melania Capasso; Boris Musset; Vladimir V Cherny; Eduardo Ríos; Martin J S Dyer; Thomas DeCoursey
Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(42):18022-7.
2009: Lisa J Russell; Melania Capasso; Inga Vater; Takashi Akasaka; Olivier A Bernard; Maria Jose Calasanz; Thiruppavaii Chandrasekaran; Elise Chapiro; Stefan Gesk; Mike Griffiths; David S Guttery; Claudia Haferlach; Lana Harder; Olaf Heidenreich; Julie Irving; Lyndal Kearney; Florence Nguyen-Khac; Lee Machado; Lynne Minto; Aneela Majid; Anthony V Moorman; Heather Morrison; Vikki Rand; Jonathan C Strefford; Claire Schwab; Holger Tönnies; Martin J S Dyer; Reiner Siebert; Christine J Harrison
Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia.
Blood 2009;114(13):2688-98.
2009: Nathalie A Johnson; Kerry J Savage; Olga Ludkovski; Susana Ben-Neriah; Ryan Woods; Christian Steidl; Martin J S Dyer; Reiner Siebert; John Kuruvilla; Richard J Klasa; Joseph Michael Connors; Randy D Gascoyne; Douglas E Horsman
Lymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survival.
Blood 2009;114(11):2273-9.
2009: Andrew G Bosanquet; Sue M Richards; Rachel Wade; Monica Else; Estella Matutes; Martin J S Dyer; Saad M B Rassam; Justin Durant; Sheila M Scadding; Steve L Raper; Claire E Dearden; Daniel Catovsky
Drug cross-resistance and therapy-induced resistance in chronic lymphocytic leukaemia by an enhanced method of individualised tumour response testing.
British journal of haematology 2009;146(4):384-95.
2009: Franck Morschhauser; John P Leonard; Luis Fayad; Bertrand Coiffier; Marie-Odile Petillon; Morton Coleman; Stephen J Schuster; Martin J S Dyer; Heather Horne; Nick Teoh; William A Wegener; David M Goldenberg
Humanized anti-CD20 antibody, veltuzumab, in refractory/recurrent non-Hodgkin's lymphoma: phase I/II results.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(20):3346-53.
2009: Inga Nagel; Takashi Akasaka; Wolfram Klapper; Stefan Gesk; Sebastian Böttcher; Matthias Ritgen; Lana Harder; Michael Kneba; Martin J S Dyer; Reiner Siebert
Identification of the gene encoding cyclin E1 (CCNE1) as a novel IGH translocation partner in t(14;19)(q32;q12) in diffuse large B-cell lymphoma.
Haematologica 2009;94(7):1020-3.
2009: M Vogler; K Weber; David Dinsdale; I Schmitz; K Schulze-Osthoff; Martin J S Dyer; Gerald M Cohen
Different forms of cell death induced by putative BCL2 inhibitors.
Cell death and differentiation 2009;16(7):1030-9.
2009: Robert S Boyd; Rebekah Jukes-Jones; Renata Walewska; David Brown; Martin J S Dyer; Kelvin Cain
Protein profiling of plasma membranes defines aberrant signaling pathways in mantle cell lymphoma.
Molecular & cellular proteomics : MCP 2009;8(7):1501-15.
2009: Pia Rivetti di Val Cervo; Paola Tucci; Aneela Majid; Massimiliano Agostini; Sergio Bernardini; Eleonora Candi; Gerry Cohen; Pierluigi Nicotera; Martin J S Dyer; Anna Maria Lena; Gerry Melino
p73, miR106b, miR34a, and Itch in chronic lymphocytic leukemia.
Blood 2009;113(25):6498-9; author reply 6499-500.
2009: Meike Vogler; Michael Butterworth; Aneela Majid; Renata Walewska; Xiao-Ming Sun; Martin J S Dyer; Gerald M Cohen
Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia.
Blood 2009;113(18):4403-13.
2009: M Vogler; David Dinsdale; Martin J S Dyer; Gerald M Cohen
Bcl-2 inhibitors: small molecules with a big impact on cancer therapy.
Cell death and differentiation 2009;16(3):360-7.
2009: Mario Rossi; Satoshi Inoue; Renata Walewska; Richard A Knight; Martin J S Dyer; Gerald M Cohen; Gerry Melino
Caspase cleavage of Itch in chronic lymphocytic leukemia cells.
Biochemical and biophysical research communications 2009;379(3):659-64.
2009: Inga Vater; Florian Wagner; Markus Kreuz; Hilmar Berger; José I Martín-Subero; Christiane Pott; Jose A Martinez-Climent; Wolfram Klapper; Kristina Krause; Martin J S Dyer; Stefan Gesk; Lana Harder; Alberto Zamò; Martin Dreyling; Dirk Hasenclever; Norbert Arnold; Reiner Siebert
GeneChip analyses point to novel pathogenetic mechanisms in mantle cell lymphoma.
British journal of haematology 2009;144(3):317-31.
2008: Maria Chiara Di Bernardo; Dalemari Crowther-Swanepoel; Peter Broderick; Emily Webb; Gabrielle Sellick; Ruth Wild; Kate Sullivan; Jayaram Vijayakrishnan; Yufei Wang; Alan Pittman; Nicola J Sunter; Andrew G Hall; Martin J S Dyer; Estella Matutes; Claire Dearden; Tryfonia Mainou-Fowler; Graham H Jackson; Geoffrey Summerfield; Robert J Harris; Andrew R Pettitt; Peter Hillmen; David J Allsup; James R Bailey; Guy Pratt; Chris Pepper; Chris Fegan; James M Allan; Daniel Catovsky; richard Houlston
A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.
Nature genetics 2008;40(10):1204-10.
2008: Dalemari Crowther-Swanepoel; Ruth Wild; Gabrielle Sellick; Martin J S Dyer; Francesca Romana Mauro; Robert J G Cuthbert; Viggo Jonsson; Estella Matutes; Claire Dearden; James Wiley; Stephen Fuller; Daniel Catovsky; richard Houlston
Insight into the pathogenesis of chronic lymphocytic leukemia (CLL) through analysis of IgVH gene usage and mutation status in familial CLL.
Blood 2008;111(12):5691-3.
2008: M Vogler; David Dinsdale; Xiao-Ming Sun; Kenneth W Young; Michael Butterworth; Pierluigi Nicotera; Martin J S Dyer; Gerald M Cohen
A novel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells.
Cell death and differentiation 2008;15(5):820-30.
2008: Satoshi Inoue; Renata Walewska; Martin J S Dyer; Gerald M Cohen
Downregulation of Mcl-1 potentiates HDACi-mediated apoptosis in leukemic cells.
Leukemia 2008;22(4):819-25.
2008: Aneela Majid; Olga Tsoulakis; Renata Walewska; Stefan Gesk; Reiner Siebert; D Ben J Kennedy; Martin J S Dyer
BCL2 expression in chronic lymphocytic leukemia: lack of association with the BCL2 938A>C promoter single nucleotide polymorphism.
Blood 2008;111(2):874-7.
2008: Lisa J Russell; Takashi Akasaka; Aneela Majid; Kei-Ji Sugimoto; E Loraine Karran; Inga Nagel; Lana Harder; Alexander Claviez; Stefan Gesk; Anthony V Moorman; Fiona Ross; Helen Mazzullo; Jon C Strefford; Reiner Siebert; Martin J S Dyer; Christine J Harrison
t(6;14)(p22;q32): a new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).
Blood 2008;111(1):387-91.
2007: Renata Walewska; Aneela Majid; Zadie Davis; P Dusanjh; D B J Kennedy; David Oscier; Martin J S Dyer
Male preponderance in chronic lymphocytic leukemia utilizing IGHV 1-69.
Leukemia 2007;21(12):2537-8.
2007: I Helbling; Renata Walewska; Martin J S Dyer; M Bamford; K E Harman
Erythema annulare centrifugum associated with chronic lymphocytic leukaemia.
The British journal of dermatology 2007;157(5):1044-5.
2007: Alessandro Natoni; Marion MacFarlane; Satoshi Inoue; Renata Walewska; Aneela Majid; Deborah Knee; David R Stover; Martin J S Dyer; Gerald M Cohen
TRAIL signals to apoptosis in chronic lymphocytic leukaemia cells primarily through TRAIL-R1 whereas cross-linked agonistic TRAIL-R2 antibodies facilitate signalling via TRAIL-R2.
British journal of haematology 2007;139(4):568-77.
2007: Gabrielle Sellick; Lynn R Goldin; Ruth W Wild; Susan L Slager; Laura Ressenti; Sara S Strom; Martin J S Dyer; Francesca Romana Mauro; Gerald E Marti; Stephen Fuller; Matthew Lyttelton; Thomas Kipps; Michael J Keating; Timothy G Call; Daniel Catovsky; Neil Caporaso; richard Houlston
A high-density SNP genome-wide linkage search of 206 families identifies susceptibility loci for chronic lymphocytic leukemia.
Blood 2007;110(9):3326-33.
2007: Martin J S Dyer; Marion MacFarlane; Gerald M Cohen
Barriers to effective TRAIL-targeted therapy of malignancy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(28):4505-6.
2007: Satoshi Inoue; J Riley; Timothy W Gant; Martin J S Dyer; Gerald M Cohen
Apoptosis induced by histone deacetylase inhibitors in leukemic cells is mediated by Bim and Noxa.
Leukemia 2007;21(8):1773-82.
2007: Daniel Catovsky; S Richards; Estella Matutes; David Oscier; Martin J S Dyer; R F Bezares; Andrew R Pettitt; Terry J Hamblin; D W Milligan; J A Child; malcolm Hamilton; Claire Dearden; A G Smith; A G Bosanquet; Zadie Davis; Vasantha Brito-Babapulle; M Else; R Wade; Peter Hillmen
Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): a randomised controlled trial.
Lancet 2007;370(9583):230-9.
2007: Ludger Sellmann; Stefan Gesk; Christoph Walter; Matthias Ritgen; Lana Harder; José I Martín-Subero; Roland Schroers; Dörte Siemer; Holger Nückel; Martin J S Dyer; Ulrich Dührsen; Reiner Siebert; Jan Dürig; Ralf Küppers
Trisomy 19 is associated with trisomy 12 and mutated IGHV genes in B-chronic lymphocytic leukaemia.
British journal of haematology 2007;138(2):217-20.
2007: José I Martín-Subero; Rachel E Ibbotson; Wolfram Klapper; L Michaux; Evelyne Callet-Bauchu; F Berger; María J Calasanz; C De Wolf-Peeters; Martin J S Dyer; Pascale Felman; Anne Gardiner; Randy D Gascoyne; Stefan Gesk; Lana Harder; D E Horsman; Michael Kneba; Ralf Küppers; A Majid; Nilima Parry-Jones; Matthias Ritgen; M Salido; F Solé; G Thiel; Hans-Heinrich Wacker; David Oscier; Iwona Wlodarska; Reiner Siebert
A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation.
Leukemia 2007;21(7):1532-44.
2007: Marc A Weniger; Stefan Gesk; Steve Ehrlich; Jose I Martin-Subero; Martin J S Dyer; Reiner Siebert; Peter Möller; Thomas F E Barth
Gains of REL in primary mediastinal B-cell lymphoma coincide with nuclear accumulation of REL protein.
Genes, chromosomes & cancer 2007;46(4):406-15.
2007: Robert S Boyd; Martin J S Dyer; Kelvin Cain
Proteomic analysis of cell surface membrane proteins in leukemic cells.
Methods in molecular biology (Clifton, N.J.) 2007;370():135-46.
2007: Cinta Mestre-Escorihuela; Fanny Rubio-Moscardo; Jose A Richter; Reiner Siebert; Joan CLIMENT; Vicente Fresquet; Elena Beltran; Xabier Agirre; Isabel Marugan; Miguel Marín; Andreas Rosenwald; Kei-Ji Sugimoto; Luise M Wheat; E Loraine Karran; Juan F García; Lydia Sanchez; Felipe Prosper; Louis M Staudt; Daniel Pinkel; Martin J S Dyer; Jose A Martinez-Climent
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas.
Blood 2007;109(1):271-80.
2006: Marc A Weniger; Karen Pulford; Stefan Gesk; S Ehrlich; Alison H Banham; L Lyne; Jose I Martin-Subero; Reiner Siebert; Martin J S Dyer; Peter Möller; Thomas F E Barth
Gains of the proto-oncogene BCL11A and nuclear accumulation of BCL11A(XL) protein are frequent in primary mediastinal B-cell lymphoma.
Leukemia 2006;20(10):1880-2.
2006: Elizabeth J Meredith; Michelle J Holder; Anders Rosén; Adrian Drake Lee; Martin J S Dyer; Nicholas M Barnes; John Gordon
Dopamine targets cycling B cells independent of receptors/transporter for oxidative attack: Implications for non-Hodgkin's lymphoma.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(36):13485-90.
2006: L M C Wheat; Susan L Kohlhaas; Johan Monbaliu; R De Coster; Aneela Majid; Renata Walewska; Martin J S Dyer
Inhibition of bortezomib-induced apoptosis by red blood cell uptake.
Leukemia 2006;20(9):1646-9.
2006: Heinrich Schwindt; Takashi Akasaka; Reina Zühlke-Jenisch; Volkmar Hans; Carlo Schaller; Wolfram Klapper; Martin J S Dyer; Reiner Siebert; Martina Deckert
Chromosomal translocations fusing the BCL6 gene to different partner loci are recurrent in primary central nervous system lymphoma and may be associated with aberrant somatic hypermutation or defective class switch recombination.
Journal of neuropathology and experimental neurology 2006;65(8):776-82.
2006: Karen Pulford; Alison H Banham; L Lyne; M Jones; Gregory Charles Ippolito; H Liu; Philip W Tucker; Giovanna Roncador; Elena Lucas; S Ashe; L Stockwin; Renata Walewska; Lorraine Karran; Randy D Gascoyne; David Y Mason; Martin J S Dyer
The BCL11AXL transcription factor: its distribution in normal and malignant tissues and use as a marker for plasmacytoid dendritic cells.
Leukemia 2006;20(8):1439-41.
2006: Satoshi Inoue; Antonello Mai; Martin J S Dyer; Gerald M Cohen
Inhibition of histone deacetylase class I but not class II is critical for the sensitization of leukemic cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.
Cancer research 2006;66(13):6785-92.
2006: Ingo Melzner; Marc A Weniger; Alexandra J Bucur; Silke Brüderlein; Karola Dorsch; Cornelia Hasel; Frank Leithäuser; Olga Ritz; Martin J S Dyer; Thomas F E Barth; Peter Möller
Biallelic deletion within 16p13.13 including SOCS-1 in Karpas1106P mediastinal B-cell lymphoma line is associated with delayed degradation of JAK2 protein.
International journal of cancer. Journal international du cancer 2006;118(8):1941-4.
2006: Catherine Burton; David C Linch; P Hoskin; Donald Milligan; Martin J S Dyer; B Hancock; P Mouncey; Paul Smith; Wendi Qian; Kenneth A MacLennan; Andrew Jack; A Webb; David Cunningham
A phase III trial comparing CHOP to PMitCEBO with or without G-CSF in patients aged 60 plus with aggressive non-Hodgkin's lymphoma.
British journal of cancer 2006;94(6):806-13.
2006: Martin J S Dyer; R Siebert
Peripheral T-cell non-Hodgkin's lymphoma NOS: naming of parts.
Leukemia 2006;20(2):208-9.
2006: Hui Liu; Gregory Charles Ippolito; Jason K Wall; Teresa Niu; Loren Probst; Baeck-Seung Lee; Karen Pulford; Alison H Banham; Luke Stockwin; Arthur L Shaffer; Louis M Staudt; Chhaya Das; Martin J S Dyer; Philip W Tucker
Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells.
Molecular cancer 2006;5():18.
2006: Fiona M Miall; Karen Harman; Ben Kennedy; Martin J S Dyer
Pyoderma gangrenosum complicating pegylated granulocyte colony-stimulating factor in Hodgkin lymphoma.
British journal of haematology 2006;132(1):115-6.
2005: Marion MacFarlane; Susan L Kohlhaas; Michael J Sutcliffe; Martin J S Dyer; Gerald M Cohen
TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies.
Cancer research 2005;65(24):11265-70.
2005: Stefan Faderl; Steven Coutré; John C Byrd; Claire Dearden; A Denes; Martin J S Dyer; S A Gregory; J G Gribben; Peter Hillmen; Michael Keating; S Rosen; P Venugopal; Kanti Rai
The evolving role of alemtuzumab in management of patients with CLL.
Leukemia 2005;19(12):2147-52.
2005: Fanny Rubio-Moscardo; David Blesa; Cinta Mestre; Reiner Siebert; Theo Balasas; Adalberto Benito; Andreas Rosenwald; Joan CLIMENT; Jose I Martinez; Markus Schilhabel; E Loraine Karran; Stefan Gesk; Manel Esteller; Ronald deLeeuw; Louis M Staudt; Jose L Fernandez-Luna; Daniel Pinkel; Martin J S Dyer; Jose A Martinez-Climent
Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes.
Blood 2005;106(9):3214-22.
2005: Gabrielle Sellick; Emily L Webb; Ruth Allinson; Estella Matutes; Martin J S Dyer; Viggo Jonsson; Anton Langerak; Francesca Romana Mauro; Stephen Fuller; James Wiley; Matthew Lyttelton; Vincenzo Callea; Martin Yuille; Daniel Catovsky; richard Houlston
A high-density SNP genomewide linkage scan for chronic lymphocytic leukemia-susceptibility loci.
American journal of human genetics 2005;77(3):420-9.
2005: Elizabeth J Meredith; Michelle J Holder; Anita Chamba; Anita Challa; Adrian Drake-Lee; Christopher M Bunce; Mark T Drayson; Geoffrey Pilkington; Randy D Blakely; Martin J S Dyer; Nicholas M Barnes; John Gordon
The serotonin transporter (SLC6A4) is present in B-cell clones of diverse malignant origin: probing a potential anti-tumor target for psychotropics.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(9):1187-9.
2005: Marion MacFarlane; Satoshi Inoue; Susan L Kohlhaas; Aneela Majid; Nicholas Harper; D B J Kennedy; Martin J S Dyer; Gerald M Cohen
Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAIL-R1.
Cell death and differentiation 2005;12(7):773-82.
2005: C Mestre; Fanny Rubio-Moscardo; Andreas Rosenwald; Joan CLIMENT; Martin J S Dyer; Louis M Staudt; D Pinkel; Reiner Siebert; Jose A Martinez-Climent
Homozygous deletion of SOCS1 in primary mediastinal B-cell lymphoma detected by CGH to BAC microarrays.
Leukemia 2005;19(6):1082-4.
2005: Fanny Rubio-Moscardo; Joan CLIMENT; Reiner Siebert; Miguel A Piris; José I Martín-Subero; Inga Nieländer; Javier Garcia-Conde; Martin J S Dyer; María José Terol; Daniel Pinkel; Jose A Martinez-Climent
Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome.
Blood 2005;105(11):4445-54.
2005: Jeanette Lundin; Ben Kennedy; Claire Dearden; Martin J S Dyer; Anders Osterborg
No cardiac toxicity associated with alemtuzumab therapy for mycosis fungoides/Sézary syndrome.
Blood 2005;105(10):4148-9.
2005: E Loraine Karran; Takashi Sonoki; Martin J S Dyer
Cloning of immunoglobulin chromosomal translocations by long-distance inverse polymerase chain reaction.
Methods in molecular medicine 2005;115():217-30.
2004: Satoshi Inoue; Marion MacFarlane; Nicholas Harper; L M C Wheat; Martin J S Dyer; Gerald M Cohen
Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies.
Cell death and differentiation 2004;11 Suppl 2():S193-206.
2004: Takashi Sonoki; TG Willis; DG Oscier; E Loraine Karran; Reiner Siebert; Martin J S Dyer
Rapid amplification of immunoglobulin heavy chain switch (IGHS) translocation breakpoints using long-distance inverse PCR.
Leukemia 2004;18(12):2026-31.
2004: Ronald deLeeuw; Jonathan J Davies; Andreas Rosenwald; Gwyn Bebb; Randy D Gascoyne; Martin J S Dyer; Louis M Staudt; Jose A Martinez-Climent; Wan L Lam
Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes.
Human molecular genetics 2004;13(17):1827-37.
2004: Satoshi Inoue; Roger T Snowden; Martin J S Dyer; Gerald M Cohen
CDDO induces apoptosis via the intrinsic pathway in lymphoid cells.
Leukemia 2004;18(5):948-52.
2004: Michael Keating; Steven Coutré; Kanti Rai; Anders Osterborg; Stefan Faderl; Ben Kennedy; Tom Kipps; Gerald P Bodey; John C Byrd; Steven Rosen; Claire Dearden; Martin J S Dyer; Peter Hillmen
Management guidelines for use of alemtuzumab in B-cell chronic lymphocytic leukemia.
Clinical lymphoma 2004;4(4):220-7.
2003: Roger T Snowden; Xiao-Ming Sun; Martin J S Dyer; Gerald M Cohen
Bisindolylmaleimide IX is a potent inducer of apoptosis in chronic lymphocytic leukaemic cells and activates cleavage of Mcl-1.
Leukemia 2003;17(10):1981-9.
2003: Martin J S Dyer
Bioweapons of tumor mass destruction?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(16):3011-2.
2003: Robert S Boyd; Paul J Adam; Sonal Patel; Julie A Loader; Joanne Berry; N T Redpath; H R Poyser; Graham C Fletcher; N A Burgess; Alasdair Stamps; L Hudson; P Smith; M Griffiths; TG Willis; E Loraine Karran; DG Oscier; Daniel Catovsky; Jonathan A Terrett; Martin J S Dyer
Proteomic analysis of the cell-surface membrane in chronic lymphocytic leukemia: identification of two novel proteins, BCNP1 and MIG2B.
Leukemia 2003;17(8):1605-12.
2003: Lihong Weng; Stefan Gesk; José I Martín-Subero; Lana Harder; Brigitte Schlegelberger; Werner Grote; Reiner Siebert; Martin J S Dyer
Interphase cytogenetic characterization of aberrations in the long arm of chromosome 1 in B-cell lymphoid malignancies.
Cancer genetics and cytogenetics 2003;144(1):83-4.
2003: Dolors Sanchez-Izquierdo; Gerard Buchonnet; Reiner Siebert; Randy D Gascoyne; Joan CLIMENT; Lorraine Karran; Miguel Marin; David Blesa; Douglas Horsman; Andreas Rosenwald; Louis M Staudt; Donna G Albertson; Ming-Qing Du; Hongtao Ye; Peter Marynen; Javier Garcia-Conde; Daniel Pinkel; Martin J S Dyer; Jose A Martinez-Climent
MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma.
Blood 2003;101(11):4539-46.
2003: Martin J S Dyer
The pathogenetic role of oncogenes deregulated by chromosomal translocation in B-cell malignancies.
International journal of hematology 2003;77(4):315-20.
2003: Grant Dewson; Roger T Snowden; Jason B Almond; Martin J S Dyer; Gerald M Cohen
Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells.
Oncogene 2003;22(17):2643-54.
2003: Jose A Martinez-Climent; Ash A Alizadeh; Richard Segraves; David Blesa; Fanny Rubio-Moscardo; Donna G Albertson; Javier Garcia-Conde; Martin J S Dyer; Ronald Levy; Daniel Pinkel; Izidore S Lossos
Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterations.
Blood 2003;101(8):3109-17.
2003: Hongtao Ye; Hongxiang Liu; Markus Raderer; Andreas Chott; Agnès Ruskone-Fourmestraux; Andrew Wotherspoon; Martin J S Dyer; Shih-Sung Chuang; Ahmet Dogan; Peter G Isaacson; Ming-Qing Du
High incidence of t(11;18)(q21;q21) in Helicobacter pylori-negative gastric MALT lymphoma.
Blood 2003;101(7):2547-50.
2003: Christiane Copie-Bergman; Marie-Laure Boulland; Catherine Dehoulle; Peter Möller; Jean-Pierre Farcet; Martin J S Dyer; Corinne Haioun; Paul-Henri Roméo; Philippe Gaulard; Karen Leroy
Interleukin 4-induced gene 1 is activated in primary mediastinal large B-cell lymphoma.
Blood 2003;101(7):2756-61.
2003: Jose A Martinez-Climent; Dolors Sanchez-Izquierdo; Elena Sarsotti; David Blesa; Isabel Benet; Joan CLIMENT; Esperanza Vizcarra; Isabel Marugan; María José Terol; Francesc Sole; Juan C Cigudosad; Reiner Siebert; Martin J S Dyer; Javier García Conde
Genomic abnormalities acquired in the blastic transformation of splenic marginal zone B-cell lymphoma.
Leukemia & lymphoma 2003;44(3):459-64.
2002: Marion MacFarlane; Nicholas Harper; Roger T Snowden; Martin J S Dyer; Georgina A Barnett; James Pringle; Gerald M Cohen
Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia.
Oncogene 2002;21(44):6809-18.
2002: Martin J S Dyer; D G Oscier
The configuration of the immunoglobulin genes in B cell chronic lymphocytic leukemia.
Leukemia 2002;16(6):973-84.
2002: Ralf Küppers; Takashi Sonoki; E Satterwhite; Stefan Gesk; Lana Harder; DG Oscier; Philip W Tucker; Martin J S Dyer; Reiner Siebert
Lack of somatic hypermutation of IG V(H) genes in lymphoid malignancies with t(2;14)(p13;q32) translocation involving the BCL11A gene.
Leukemia 2002;16(5):937-9.
2002: José I Martín-Subero; Lana Harder; Stefan Gesk; Brigitte Schlegelberger; Werner Grote; Jose A Martinez-Climent; Martin J S Dyer; Francisco J Novo; María J Calasanz; Reiner Siebert
Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci.
International journal of cancer. Journal international du cancer 2002;98(3):470-4.
2002: José I Martín-Subero; Stefan Gesk; Lana Harder; Takashi Sonoki; Philip W Tucker; Brigitte Schlegelberger; Werner Grote; Francisco J Novo; María J Calasanz; Martin-Leo Hansmann; Martin J S Dyer; Reiner Siebert
Recurrent involvement of the REL and BCL11A loci in classical Hodgkin lymphoma.
Blood 2002;99(4):1474-7.
2001: Jose A Martinez-Climent; Esperanza Vizcarra; D Sanchez; David Blesa; Isabel Marugan; Isabel Benet; Francesc Sole; Fanny Rubio-Moscardo; María José Terol; Joan CLIMENT; Elena Sarsotti; Mar Tormo; ENRIQUE J. ANDREU; Marta Salido; M A Ruiz; Felipe Prosper; Reiner Siebert; Martin J S Dyer; Javier García Conde
Loss of a novel tumor suppressor gene locus at chromosome 8p is associated with leukemic mantle cell lymphoma.
Blood 2001;98(12):3479-82.
2001: E Satterwhite; Takashi Sonoki; TG Willis; Lana Harder; R Nowak; E L Arriola; Hongxiang Liu; Helen Price; Stefan Gesk; Doris Steinemann; Brigitte Schlegelberger; DG Oscier; Reiner Siebert; Philip W Tucker; Martin J S Dyer
The BCL11 gene family: involvement of BCL11A in lymphoid malignancies.
Blood 2001;98(12):3413-20.
2001: Takashi Sonoki; Lana Harder; D E Horsman; Lorraine Karran; I Taniguchi; TG Willis; Stefan Gesk; Doris Steinemann; E Zucca; Brigitte Schlegelberger; Francesc Solé; Andrew Mungall; Randy D Gascoyne; Reiner Siebert; Martin J S Dyer
Cyclin D3 is a target gene of t(6;14)(p21.1;q32.3) of mature B-cell malignancies.
Blood 2001;98(9):2837-44.
2001: Claire Dearden; Estella Matutes; B Cazin; Geir Tjønnfjord; A Parreira; B Nomdedeu; P Leoni; F J Clark; D Radia; S M Rassam; T Roques; N Ketterer; Vasantha Brito-Babapulle; Martin J S Dyer; Daniel Catovsky
High remission rate in T-cell prolymphocytic leukemia with CAMPATH-1H.
Blood 2001;98(6):1721-6.
2001: Dolors Sanchez-Izquierdo; Reiner Siebert; Lana Harder; Isabel Marugan; A Gozzetti; Helen Price; Stefan Gesk; J M Hernandez-Rivas; Isabel Benet; Francesc Solé; Takashi Sonoki; Michelle M Le Beau; Brigitte Schlegelberger; Martin J S Dyer; Javier Garcia-Conde; Jose A Martinez-Climent
Detection of translocations affecting the BCL6 locus in B cell non-Hodgkin's lymphoma by interphase fluorescence in situ hybridization.
Leukemia 2001;15(9):1475-84.
2001: Lorraine Karran; Martin J S Dyer
Proteolytic cleavage of molecules involved in cell death or survival pathways: a role in the control of apoptosis?
Critical reviews in eukaryotic gene expression 2001;11(4):269-77.
2000: Hongtao Ye; Ahmet Dogan; Lorraine Karran; TG Willis; L Chen; I Wlodarska; Martin J S Dyer; Peter G Isaacson; Ming-Qing Du
BCL10 expression in normal and neoplastic lymphoid tissue. Nuclear localization in MALT lymphoma.
The American journal of pathology 2000;157(4):1147-54.
2000: PJ De Schouwer; Martin J S Dyer; Vasantha Brito-Babapulle; Estella Matutes; Daniel Catovsky; Martin Yuille
T-cell prolymphocytic leukaemia: antigen receptor gene rearrangement and a novel mode of MTCP1 B1 activation.
British journal of haematology 2000;110(4):831-8.
2000: TG Willis; Martin J S Dyer
The role of immunoglobulin translocations in the pathogenesis of B-cell malignancies.
Blood 2000;96(3):808-22.
2000: Ming-Qing Du; H Peng; Hongxiang Liu; Rifat A Hamoudi; Tim C Diss; TG Willis; Hongtao Ye; Ahmet Dogan; Andrew C Wotherspoon; Martin J S Dyer; Peter G Isaacson
BCL10 gene mutation in lymphoma.
Blood 2000;95(12):3885-90.
1999: Lionel J Coignet; C S Lima; Toon Min; B Streubel; John Swansbury; N Telford; S Swanton; A Bowen; M Nagai; Daniel Catovsky; C Fonatsch; Martin J S Dyer
Myeloid- and lymphoid-specific breakpoint cluster regions in chromosome band 13q14 in acute leukemia.
Genes, chromosomes & cancer 1999;25(3):222-9.
1999: Daniela Lens; Lionel J Coignet; Vasantha Brito-Babapulle; C S Lima; Estella Matutes; Martin J S Dyer; Daniel Catovsky
B cell prolymphocytic leukaemia (B-PLL) with complex karyotype and concurrent abnormalities of the p53 and c-MYC gene.
Leukemia 1999;13(6):873-6.
1999: TG Willis; Dalal M Jadayel; Ming-Qing Du; H Peng; AR Perry; M Abdul-Rauf; Helen Price; Lorraine Karran; O Majekodunmi; I Wlodarska; L Pan; Tim Crook; Rifat A Hamoudi; Peter G Isaacson; Martin J S Dyer
Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types.
Cell 1999;96(1):35-45.
1998: Dalal M Jadayel; Lucy Osborne; Lionel J Coignet; V J Zani; L C Tsui; S W Scherer; Martin J S Dyer
The BCL7 gene family: deletion of BCL7B in Williams syndrome.
Gene 1998;224(1-2):35-44.
1998: TG Willis; I R Zalcberg; Lionel J Coignet; I Wlodarska; M Stul; Dalal M Jadayel; C Bastard; Jennifer Treleaven; Daniel Catovsky; M L Silva; Martin J S Dyer
Molecular cloning of translocation t(1;14)(q21;q32) defines a novel gene (BCL9) at chromosome 1q21.
Blood 1998;91(6):1873-81.
1998: MA Yuille; Lionel J Coignet; S M Abraham; F Yaqub; L Luo; Estella Matutes; Vasantha Brito-Babapulle; Igor Vorechovský; Martin J S Dyer; Daniel Catovsky
ATM is usually rearranged in T-cell prolymphocytic leukaemia.
Oncogene 1998;16(6):789-96.
1998: Lia Ginaldi; Massimo De Martinis; Estella Matutes; Nahla farahat; Ricardo Morilla; Martin J S Dyer; Daniel Catovsky
Levels of expression of CD52 in normal and leukemic B and T cells: correlation with in vivo therapeutic responses to Campath-1H.
Leukemia research 1998;22(2):185-91.
1997: Daniela Lens; Martin J S Dyer; Jose Antonio Garcia-Marco; PJ De Schouwer; Rifat A Hamoudi; D Jones; Nahla farahat; Estella Matutes; Daniel Catovsky
p53 abnormalities in CLL are associated with excess of prolymphocytes and poor prognosis.
British journal of haematology 1997;99(4):848-57.
1997: TG Willis; Dalal M Jadayel; Lionel J Coignet; M Abdul-Rauf; Jennifer Treleaven; Daniel Catovsky; Martin J S Dyer
Rapid molecular cloning of rearrangements of the IGHJ locus using long-distance inverse polymerase chain reaction.
Blood 1997;90(6):2456-64.
1997: Igor Vorechovský; L Luo; Martin J S Dyer; Daniel Catovsky; Peter L Amlot; J C Yaxley; Letizia Foroni; Lennart Hammarström; A David B Webster; MA Yuille
Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukaemia.
Nature genetics 1997;17(1):96-9.
1997: R Pawson; Martin J S Dyer; R Barge; Estella Matutes; P D Thornton; E Emmett; J C Kluin-Nelemans; W E Fibbe; R Willemze; Daniel Catovsky
Treatment of T-cell prolymphocytic leukemia with human CD52 antibody.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(7):2667-72.
1997: Martin J S Dyer; S M Kelsey; H J Mackay; E Emmett; P Thornton; G Hale; H Waldmann; A C Newland; Daniel Catovsky
In vivo 'purging' of residual disease in CLL with Campath-1H.
British journal of haematology 1997;97(3):669-72.
1997: Daniela Lens; PJ De Schouwer; Rifat A Hamoudi; M Abdul-Rauf; Nahla farahat; Estella Matutes; Tim Crook; Martin J S Dyer; Daniel Catovsky
p53 abnormalities in B-cell prolymphocytic leukemia.
Blood 1997;89(6):2015-23.
1997: A L Bowen; A Zomas; E Emmett; Estella Matutes; Martin J S Dyer; Daniel Catovsky
Subcutaneous CAMPATH-1H in fludarabine-resistant/relapsed chronic lymphocytic and B-prolymphocytic leukaemia.
British journal of haematology 1997;96(3):617-9.
1997: Dalal M Jadayel; J Lukas; E Nacheva; J Bartkova; G Stranks; PJ De Schouwer; Daniela Lens; J Bartek; Martin J S Dyer; A R Kruger; Daniel Catovsky
Potential role for concurrent abnormalities of the cyclin D1, p16CDKN2 and p15CDKN2B genes in certain B cell non-Hodgkin's lymphomas. Functional studies in a cell line (Granta 519).
Leukemia 1997;11(1):64-72.
1996: M A Yuille; S Galiegue-Zouitina; LR Hiorns; Dalal M Jadayel; PJ De Schouwer; Daniel Catovsky; Martin J S Dyer; Jean-Pierre Kerckaert
Heterogeneity of breakpoints at the transcriptional co-activator gene, BOB-1, in lymphoproliferative disease.
Leukemia 1996;10(9):1492-6.
1996: Martin J S Dyer; Debra M Lillington; Christian Bastard; H Tilly; Daniela Lens; J M Heward; G Stranks; Ricardo Morilla; S Monrad; P Guglielmi; J C Kluin-Nelemans; Anne Hagemeijer; Bryan D Young; Daniel Catovsky
Concurrent activation of MYC and BCL2 in B cell non-Hodgkin lymphoma cell lines by translocation of both oncogenes to the same immunoglobulin heavy chain locus.
Leukemia 1996;10(7):1198-208.
1996: S E Height; G John Swansbury; Estella Matutes; Jennifer Treleaven; Daniel Catovsky; Martin J S Dyer
Analysis of clonal rearrangements of the Ig heavy chain locus in acute leukemia.
Blood 1996;87(12):5242-50.
1996: V J Zani; Norio Asou; Dalal M Jadayel; J M Heward; Janet Shipley; Elisabeth P Nacheva; K Takasuki; Daniel Catovsky; Martin J S Dyer
Molecular cloning of complex chromosomal translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon.
Blood 1996;87(8):3124-34.
1996: S Galiéque Zouitina; Sabine Quief; M P Hildebrand; Claude Denis; G Lecocq; M Collyn-d'Hooghe; Christian Bastard; M Yuille; Martin J S Dyer; Jean-Pierre Kerckaert
The B cell transcriptional coactivator BOB1/OBF1 gene fuses to the LAZ3/BCL6 gene by t(3;11)(q27;q23.1) chromosomal translocation in a B cell leukemia line (Karpas 231).
Leukemia 1996;10(4):579-87.
1995: Philip M Kluin; H Kayano; V J Zani; Hanneke C Kluin-Nelemans; P W Tucker; E Satterwhite; Martin J S Dyer
IgD class switching: identification of a novel recombination site in neoplastic and normal B cells.
European journal of immunology 1995;25(12):3504-8.
1995: Sylvie Galiègue-Zouitina; Sabine Quief; M P Hildebrand; Claude Denis; G Lecocq; M Collyn-d'Hooghe; Christian Bastard; M Yuille; Martin J S Dyer; Jean-Pierre Kerckaert
Fusion of the LAZ3/BCL6 and BOB1/OBF1 genes by t(3; 11) (q27; q23) chromosomal translocation.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1995;318(11):1125-31.
1995: Dalal M Jadayel; G Calabrese; Toon Min; F van Rhee; G John Swansbury; Martin J S Dyer; J Maitland; G Palka; Daniel Catovsky
Molecular cytogenetics of chronic myeloid leukemia with atypical t(6;9) (p23;q34) translocation.
Leukemia 1995;9(6):981-7.
1994: Elisabeth P Nacheva; Martin J S Dyer; C Metivier; Dalal M Jadayel; G Stranks; Ricardo Morilla; J M Heward; T Holloway; S O'Connor; P C Bevan
B-cell non-Hodgkin's lymphoma cell line (Karpas 1106) with complex translocation involving 18q21.3 but lacking BCL2 rearrangement and expression.
Blood 1994;84(10):3422-8.
1994: S Agrawal; Estella Matutes; J Voke; Martin J S Dyer; T Khokhar; Daniel Catovsky
Persistent polyclonal B-cell lymphocytosis.
Leukemia research 1994;18(10):791-5.
1994: S E Height; Melissa G Dainton; L Kearney; G John Swansbury; Estella Matutes; Martin J S Dyer; Jennifer Treleaven; Raymond L Powles; Daniel Catovsky
Acute myelomonocytic leukemia with t(10;11)(p13;q23): heterogeneity of breakpoints at 11q23 and association with recombinase activation.
Genes, chromosomes & cancer 1994;11(2):136-9.
1994: Jiri Lukas; Dalal M Jadayel; Jirina Bartkova; Elisabeth P Nacheva; Martin J S Dyer; M Strauss; Jiri Bartek
BCL-1/cyclin D1 oncoprotein oscillates and subverts the G1 phase control in B-cell neoplasms carrying the t(11;14) translocation.
Oncogene 1994;9(8):2159-67.
1994: Martin J S Dyer; V J Zani; W Z Lu; A O'Byrne; S Mould; R Chapman; J M Heward; H Kayano; Dalal M Jadayel; Estella Matutes
BCL2 translocations in leukemias of mature B cells.
Blood 1994;83(12):3682-8.
1994: Dalal M Jadayel; Estella Matutes; Martin J S Dyer; Vasantha Brito-Babapulle; M T Khohkar; David Oscier; Daniel Catovsky
Splenic lymphoma with villous lymphocytes: analysis of BCL-1 rearrangements and expression of the cyclin D1 gene.
Blood 1994;83(12):3664-71.
1994: LR Hiorns; Toon Min; G John Swansbury; A Zelent; Martin J S Dyer; Daniel Catovsky
Interstitial insertion of retinoic acid receptor-alpha gene in acute promyelocytic leukemia with normal chromosomes 15 and 17.
Blood 1994;83(10):2946-51.
1994: H Kayano; Martin J S Dyer; V J Zani; M A Laffan; Estella Matutes; Norio Asou; I Katayama; Daniel Catovsky
Aberrant rearrangements within the immunoglobulin heavy chain locus in hairy cell leukemia.
Leukemia & lymphoma 1994;14 Suppl 1():41-7.
1993: Martin J S Dyer; J M Heward; V J Zani; V Buccheri; Daniel Catovsky
Unusual deletions within the immunoglobulin heavy-chain locus in acute leukemias.
Blood 1993;82(3):865-71.
1993: V Buccheri; B Mihaljević; Estella Matutes; Martin J S Dyer; D Y Mason; Daniel Catovsky
mb-1: a new marker for B-lineage lymphoblastic leukemia.
Blood 1993;82(3):853-7.
1993: Martin J S Dyer; Elisabeth P Nacheva; P Fischer; J M Heward; W Labastide; A Karpas
A new human T-cell lymphoma cell line (Karpas 384) of the T-cell receptor gamma/delta lineage with translocation t(7:14) (p13;q11.2).
Leukemia 1993;7(7):1047-53.
1993: Elisabeth P Nacheva; Martin J S Dyer; P Fischer; G Stranks; J M Heward; R E Marcus; Colin Grace; A Karpas
C-MYC translocations in de novo B-cell lineage acute leukemias with t(14;18)(cell lines Karpas 231 and 353).
Blood 1993;82(1):231-40.
1993: V Buccheri; Estella Matutes; Martin J S Dyer; Daniel Catovsky
Lineage commitment in biphenotypic acute leukemia.
Leukemia 1993;7(6):919-27.
1990: Martin J S Dyer; P Fischer; Elisabeth P Nacheva; W Labastide; A Karpas
A new human B-cell non-Hodgkin's lymphoma cell line (Karpas 422) exhibiting both t (14;18) and t(4;11) chromosomal translocations.
Blood 1990;75(3):709-14.
1989: Martin J S Dyer
T-cell receptor delta/alpha rearrangements in lymphoid neoplasms.
Blood 1989;74(3):1073-83.
1989: Martin J S Dyer; Geoff Hale; F G Hayhoe; Herman Waldmann
Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: influence of antibody isotype.
Blood 1989;73(6):1431-9.