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Carrie Dykes

Research Profile

Living Beings

HIV-1

Physiology

Chemicals & Drugs

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Publications

TOP 3
Xinyan Zhang; Hongyu Jiang; Gene Morse; Camlin Tierney; Mary Albrecht; Lisa M Demeter; Robin DiFrancesco; Carrie Dykes; David W Haas
Discordant associations between SLCO1B1 521T→C and plasma levels of ritonavir-boosted protease inhibitors in AIDS clinical trials group study A5146.
Olivia Block; Anirban Mitra; Lukas Novotny; Carrie Dykes
A rapid label-free method for quantitation of human immunodeficiency virus type-1 particles by nanospectroscopy.
Jiong Wang; Hulin Wu; Gang Zhang; Robert A Bambara; Lisa M Demeter; Dongge Li; Hua Liang; Nicholas R Lowe; Hannah M Smith; Carrie Dykes
Nonnucleoside reverse transcriptase inhibitor-resistant HIV is stimulated by efavirenz during early stages of infection.

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All Publications

2013: Xinyan Zhang; Hongyu Jiang; Gene Morse; Camlin Tierney; Mary Albrecht; Lisa M Demeter; Robin DiFrancesco; Carrie Dykes; David W Haas
Discordant associations between SLCO1B1 521T→C and plasma levels of ritonavir-boosted protease inhibitors in AIDS clinical trials group study A5146.
Therapeutic drug monitoring 2013;35(2):209-16.
2012: Olivia Block; Anirban Mitra; Lukas Novotny; Carrie Dykes
A rapid label-free method for quantitation of human immunodeficiency virus type-1 particles by nanospectroscopy.
Journal of virological methods 2012;182(1-2):70-5.
2011: Jiong Wang; Hulin Wu; Gang Zhang; Robert A Bambara; Lisa M Demeter; Dongge Li; Hua Liang; Nicholas R Lowe; Hannah M Smith; Carrie Dykes
Nonnucleoside reverse transcriptase inhibitor-resistant HIV is stimulated by efavirenz during early stages of infection.
Journal of virology 2011;85(20):10861-73.
2011: Mary Albrecht; Carrie Dykes; Karin L Klingman; Gene D Morse; A Lisa Mukherjee; Camlin Tierney; Lisa M Demeter
A randomized clinical trial evaluating therapeutic drug monitoring (TDM) for protease inhibitor-based regimens in antiretroviral-experienced HIV-infected individuals: week 48 results of the A5146 study.
HIV clinical trials 2011;12(4):201-14.
2011: Dorota Piekna-Przybylska; Carrie Dykes; Lisa M Demeter; Robert A Bambara
Sequences in the U3 region of human immunodeficiency virus 1 improve efficiency of minus strand transfer in infected cells.
Virology 2011;410(2):368-74.
2010: Carrie Dykes; Hulin Wu; Matthew Sims; J Holden-Wiltse; Lisa M Demeter
Human immunodeficiency virus type 1 protease inhibitor drug-resistant mutants give discordant results when compared in single-cycle and multiple-cycle fitness assays.
Journal of clinical microbiology 2010;48(11):4035-43.
2010: Jiong Wang; Robert A Bambara; Lisa M Demeter; Carrie Dykes
Reduced fitness in cell culture of HIV-1 with nonnucleoside reverse transcriptase inhibitor-resistant mutations correlates with relative levels of reverse transcriptase content and RNase H activity in virions.
Journal of virology 2010;84(18):9377-89.
2010: Jiong Wang; H Liang; Lee Bacheler; Hulin Wu; K Deriziotis; Lisa M Demeter; Carrie Dykes
The non-nucleoside reverse transcriptase inhibitor efavirenz stimulates replication of human immunodeficiency virus type 1 harboring certain non-nucleoside resistance mutations.
Virology 2010;402(2):228-37.
2010: Jingming Ma; Carrie Dykes; Tao Wu; Yangxin Huang; Lisa Demeter; Hulin Wu
vFitness: a web-based computing tool for improving estimation of in vitro HIV-1 fitness experiments.
BMC bioinformatics 2010;11():261.
2009: Hongyu Miao; Carrie Dykes; Lisa M Demeter; Hulin Wu
Differential equation modeling of HIV viral fitness experiments: model identification, model selection, and multimodel inference.
Biometrics 2009;65(1):292-300.
2009: Lisa M Demeter; Hongyu Jiang; A Lisa Mukherjee; Gene D Morse; Robin DiFrancesco; Robert DiCenzo; Carrie Dykes; Prakash Sista; Lee Bacheler; Karin Klingman; Alex Rinehart; Mary Albrecht
A randomized trial of therapeutic drug monitoring of protease inhibitors in antiretroviral-experienced, HIV-1-infected patients.
AIDS (London, England) 2009;23(3):357-68.
2008: Hongyu Miao; Carrie Dykes; Lisa M Demeter; James Cavenaugh; Sung Yong Park; Alan S Perelson; Hulin Wu
Modeling and estimation of kinetic parameters and replicative fitness of HIV-1 from flow-cytometry-based growth competition experiments.
Bulletin of mathematical biology 2008;70(6):1749-71.
2007: Carrie Dykes; Lisa M Demeter
Clinical significance of human immunodeficiency virus type 1 replication fitness.
Clinical microbiology reviews 2007;20(4):550-78.
2006: Christine E Koval; Carrie Dykes; Jiong Wang; Lisa M Demeter
Relative replication fitness of efavirenz-resistant mutants of HIV-1: correlation with frequency during clinical therapy and evidence of compensation for the reduced fitness of K103N + L100I by the nucleoside resistance mutation L74V.
Virology 2006;353(1):184-92.
2006: Carrie Dykes; Jiong Wang; Xia Jin; Vicente Planelles; Dong Sung An; Amanda Tallo; Yangxin Huang; Hulin Wu; Lisa M Demeter
Evaluation of a multiple-cycle, recombinant virus, growth competition assay that uses flow cytometry to measure replication efficiency of human immunodeficiency virus type 1 in cell culture.
Journal of clinical microbiology 2006;44(6):1930-43.
2006: Jiong Wang; Carrie Dykes; Robert A Domaoal; Christine E Koval; Robert A Bambara; Lisa M Demeter
The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNA(Lys, 3) that correlate with reductions in replication efficiency.
Virology 2006;348(2):462-74.
2006: Hulin Wu; Yangxin Huang; Carrie Dykes; Dacheng Liu; Jingming Ma; Alan S Perelson; Lisa M Demeter
Modeling and estimation of replication fitness of human immunodeficiency virus type 1 in vitro experiments by using a growth competition assay.
Journal of virology 2006;80(5):2380-9.
2004: Carrie Dykes; Mini Balakrishnan; Vicente Planelles; Yonghong Zhu; Robert A Bambara; Lisa M Demeter
Identification of a preferred region for recombination and mutation in HIV-1 gag.
Virology 2004;326(2):262-79.
2004: Carrie Dykes; Joe Najjar; Ronald J Bosch; Michael Wantman; Manohar Furtado; Stephen Hart; Scott M Hammer; Lisa M Demeter
Detection of drug-resistant minority variants of HIV-1 during virologic failure of indinavir, lamivudine, and zidovudine.
The Journal of infectious diseases 2004;189(6):1091-6.
2001: Carrie Dykes; K Fox; A Lloyd; M Chiulli; E Morse; Lisa M Demeter
Impact of clinical reverse transcriptase sequences on the replication capacity of HIV-1 drug-resistant mutants.
Virology 2001;285(2):193-203.
2000: RH Archer; Carrie Dykes; P Gerondelis; A Lloyd; Philip J Fay; Richard C Reichman; Robert A Bambara; Lisa M Demeter
Mutants of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors demonstrate altered rates of RNase H cleavage that correlate with HIV-1 replication fitness in cell culture.
Journal of virology 2000;74(18):8390-401.
2000: Carrie Dykes; P Mootsikapun; A Dexter; L Berrios; M Chiulli; Richard C Reichman; Lisa M Demeter
Analysis of env sequence evolution in human immunodeficiency virus-infected patients receiving therapy with nonnucleoside reverse-transcriptase inhibitors.
The Journal of infectious diseases 2000;182(1):316-20.