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Linda Dykstra

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TOP 3
Rebecca E Balter; Linda A Dykstra
Thermal sensitivity as a measure of spontaneous morphine withdrawal in mice.
Rebecca E Balter; Linda A Dykstra
The effect of environmental factors on morphine withdrawal in C57BL/6J mice: running wheel access and group housing.
Mitchell J Picker; Dana Daugherty; Fredrick E Henry; Laurence L Miller; Linda A Dykstra
Metabotropic glutamate antagonists alone and in combination with morphine: comparison across two models of acute pain and a model of persistent, inflammatory pain.

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All Publications

2013: Rebecca E Balter; Linda A Dykstra
Thermal sensitivity as a measure of spontaneous morphine withdrawal in mice.
Journal of pharmacological and toxicological methods 2013;67(3):162-8.
2012: Rebecca E Balter; Linda A Dykstra
The effect of environmental factors on morphine withdrawal in C57BL/6J mice: running wheel access and group housing.
Psychopharmacology 2012;224(1):91-100.
2011: Mitchell J Picker; Dana Daugherty; Fredrick E Henry; Laurence L Miller; Linda A Dykstra
Metabotropic glutamate antagonists alone and in combination with morphine: comparison across two models of acute pain and a model of persistent, inflammatory pain.
Behavioural pharmacology 2011;22(8):785-93.
2011: Linda A Dykstra; Bradford D Fischer; Fredrick E Henry; Rebecca E Balter; Karl T Schmidt; Laurence L Miller
Opioid antinociception, tolerance and dependence: interactions with the N-methyl-D-aspartate system in mice.
Behavioural pharmacology 2011;22(5-6):540-7.
2011: Laurence L Miller; Mitchell J Picker; Karl T Schmidt; Linda A Dykstra
Effects of morphine on pain-elicited and pain-suppressed behavior in CB1 knockout and wildtype mice.
Psychopharmacology 2011;215(3):455-65.
2010: Bradford D Fischer; Sara J Ward; Fredrick E Henry; Linda A Dykstra
Attenuation of morphine antinociceptive tolerance by a CB(1) receptor agonist and an NMDA receptor antagonist: Interactive effects.
Neuropharmacology 2010;58(2):544-50.
2009: Sara Jane Ward; Marisa Rosenberg; Linda A Dykstra; Ellen A Walker
The CB1 antagonist rimonabant (SR141716) blocks cue-induced reinstatement of cocaine seeking and other context and extinction phenomena predictive of relapse.
Drug and alcohol dependence 2009;105(3):248-55.
2008: Laurence L Miller; Sara J Ward; Linda A Dykstra
Chronic unpredictable stress enhances cocaine-conditioned place preference in type 1 cannabinoid receptor knockout mice.
Behavioural pharmacology 2008;19(5-6):575-81.
2008: Bradford D Fischer; Laurence L Miller; Fredrick E Henry; Mitchell J Picker; Linda A Dykstra
Increased efficacy of micro-opioid agonist-induced antinociception by metabotropic glutamate receptor antagonists in C57BL/6 mice: comparison with (-)-6-phosphonomethyl-deca-hydroisoquinoline-3-carboxylic acid (LY235959).
Psychopharmacology 2008;198(2):271-8.
2008: Bradford D Fischer; Eric I Zimmerman; Mitchell J Picker; Linda A Dykstra
Morphine in combination with metabotropic glutamate receptor antagonists on schedule-controlled responding and thermal nociception.
The Journal of pharmacology and experimental therapeutics 2008;324(2):732-9.
2007: Sara Jane Ward; Ellen A Walker; Linda A Dykstra
Effect of cannabinoid CB1 receptor antagonist SR141716A and CB1 receptor knockout on cue-induced reinstatement of Ensure and corn-oil seeking in mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(12):2592-600.
2007: Kelly A Carrigan; Linda A Dykstra
Behavioral effects of morphine and cocaine in M1 muscarinic acetylcholine receptor-deficient mice.
Psychopharmacology 2007;191(4):985-93.
2007: Richard M Allen; Linda A Dykstra; Regina M Carelli
Continuous exposure to the competitive N-methyl-D: -aspartate receptor antagonist, LY235959, facilitates escalation of cocaine consumption in Sprague-Dawley rats.
Psychopharmacology 2007;191(2):341-51.
2006: Bradford D Fischer; Linda A Dykstra
Interactions between an N-methyl-D-aspartate antagonist and low-efficacy opioid receptor agonists in assays of schedule-controlled responding and thermal nociception.
The Journal of pharmacology and experimental therapeutics 2006;318(3):1300-6.
2005: Richard M Allen; Regina M Carelli; Linda A Dykstra; Therese L Suchey; Carson V Everett
Effects of the competitive N-methyl-D-aspartate receptor antagonist, LY235959 [(-)-6-phosphonomethyl-deca-hydroisoquinoline-3-carboxylic acid], on responding for cocaine under both fixed and progressive ratio schedules of reinforcement.
The Journal of pharmacology and experimental therapeutics 2005;315(1):449-57.
2005: S J Ward; Linda A Dykstra
The role of CB1 receptors in sweet versus fat reinforcement: effect of CB1 receptor deletion, CB1 receptor antagonism (SR141716A) and CB1 receptor agonism (CP-55940).
Behavioural pharmacology 2005;16(5-6):381-8.
2005: Bradford D Fischer; Kelly A Carrigan; Linda A Dykstra
Effects of N-methyl-D-aspartate receptor antagonists on acute morphine-induced and l-methadone-induced antinociception in mice.
The journal of pain : official journal of the American Pain Society 2005;6(7):425-33.
2005: Christine E Hughes; Stacey C Sigmon; Raymond C Pitts; Linda A Dykstra
Morphine tolerance as a function of ratio schedule: response requirement or unit price?
Journal of the experimental analysis of behavior 2005;83(3):281-96.
2004: Ivy Carroll; James B Thomas; Linda A Dykstra; Arthur L Granger; Richard M Allen; James L Howard; Gerald T Pollard; Mario D Aceto; Louis S Harris
Pharmacological properties of JDTic: a novel kappa-opioid receptor antagonist.
European journal of pharmacology 2004;501(1-3):111-9.
2004: Ellen A Walker; Mitchell J Picker; Arthur L Granger; Linda A Dykstra
Effects of opioids in morphine-treated pigeons trained to discriminate among morphine, the low-efficacy agonist nalbuphine, and saline.
The Journal of pharmacology and experimental therapeutics 2004;310(1):150-8.
2003: Richard M Allen; Arthur L Granger; Linda A Dykstra
The competitive N-methyl-D-aspartate receptor antagonist (-)-6-phosphonomethyl-deca-hydroisoquinoline-3-carboxylic acid (LY235959) potentiates the antinociceptive effects of opioids that vary in efficacy at the mu-opioid receptor.
The Journal of pharmacology and experimental therapeutics 2003;307(2):785-92.
2002: Linda A Dykstra; Arthur L Granger; Richard M Allen; Xiaoyan Zhang; Kenner C Rice
Antinociceptive effects of the selective delta opioid agonist SNC80 alone and in combination with mu opioids in the squirrel monkey titration procedure.
Psychopharmacology 2002;163(3-4):420-9.
2002: Richard M Allen; Arthur L Granger; Linda A Dykstra
Dextromethorphan potentiates the antinociceptive effects of morphine and the delta-opioid agonist SNC80 in squirrel monkeys.
The Journal of pharmacology and experimental therapeutics 2002;300(2):435-41.
2001: Richard M Allen; Linda A Dykstra
N-methyl-D-aspartate receptor antagonists potentiate the antinociceptive effects of morphine in squirrel monkeys.
The Journal of pharmacology and experimental therapeutics 2001;298(1):288-97.
2001: Ellen A Walker; Mitchell J Picker; Linda A Dykstra
Three-choice discrimination in pigeons is based on relative efficacy differences among opioids.
Psychopharmacology 2001;155(4):389-96.
2000: Richard M Allen; Linda A Dykstra
Attenuation of mu-opioid tolerance and cross-tolerance by the competitive N-methyl-D-aspartate receptor antagonist LY235959 is related to tolerance and cross-tolerance magnitude.
The Journal of pharmacology and experimental therapeutics 2000;295(3):1012-21.
2000: Richard M Allen; Linda A Dykstra
Role of morphine maintenance dose in the development of tolerance and its attenuation by an NMDA receptor antagonist.
Psychopharmacology 2000;148(1):59-65.
1999: J Paige West; Linda A Dykstra; Donald T Lysle
Immunomodulatory effects of morphine withdrawal in the rat are time dependent and reversible by clonidine.
Psychopharmacology 1999;146(3):320-7.
1999: Ellen A Walker; E R Hawkins; M J Tiano; Mitchell J Picker; Linda A Dykstra
Discriminative stimulus effects of nalbuphine in nontreated and morphine-treated pigeons.
Pharmacology, biochemistry, and behavior 1999;64(2):445-8.
1999: Ellen A Walker; M J Tiano; S I Benyas; Linda A Dykstra; Mitchell J Picker
Naltrexone and beta-funaltrexamine antagonism of the antinociceptive and response rate-decreasing effects of morphine, dezocine, and d-propoxyphene.
Psychopharmacology 1999;144(1):45-53.
1999: Richard M Allen; Linda A Dykstra
The competitive NMDA receptor antagonist LY235959 modulates the progression of morphine tolerance in rats.
Psychopharmacology 1999;142(2):209-14.
1998: J Paige West; Linda A Dykstra; Donald T Lysle
Differential tolerance to morphine's immunomodulatory effects following continuous administration.
Drug and alcohol dependence 1998;53(1):31-8.
1998: Raymond C Pitts; Richard M Allen; Ellen A Walker; Linda A Dykstra
Clocinnamox antagonism of the antinociceptive effects of mu opioids in squirrel monkeys.
The Journal of pharmacology and experimental therapeutics 1998;285(3):1197-206.
1998: Christina J Nelson; Linda A Dykstra; Donald T Lysle
Morphine's immunologic and analgesic effects. Comparison of time course.
Advances in experimental medicine and biology 1998;437():169-75.
1997: Karamarie Fecho; K A Maslonek; Linda A Dykstra; Donald T Lysle
Acetylcholinesterase monoclonal antibody-induced sympathectomy: effects on immune status and acute morphine-induced immunomodulation.
Brain, behavior, and immunity 1997;11(3):167-84.
1997: Christina J Nelson; Linda A Dykstra; Donald T Lysle
Comparison of the time course of morphine's analgesic and immunologic effects.
Anesthesia and analgesia 1997;85(3):620-6.
1997: J Paige West; Donald T Lysle; Linda A Dykstra
Tolerance development to morphine-induced alterations of immune status.
Drug and alcohol dependence 1997;46(3):147-57.
1997: Christine E Hughes; Linda A Dykstra
Antagonism of the response rate-decreasing effects of meperidine and morphine by beta-funaltrexamine and naltrexone in squirrel monkeys.
Drug and alcohol dependence 1997;45(3):197-206.
1997: Linda A Dykstra; Kenzie L. Preston; George E Bigelow
Discriminative stimulus and subjective effects of opioids with mu and kappa activity: data from laboratory animals and human subjects.
Psychopharmacology 1997;130(1):14-27.
1996: K R Powell; Linda A Dykstra
The role of serotonergic receptors in the effects of mu opioids in squirrel monkeys responding under a titration procedure.
Psychopharmacology 1996;126(1):42-9.
1996: Donald T Lysle; K E Hoffman; Linda A Dykstra
Evidence for the involvement of the caudal region of the periaqueductal gray in a subset of morphine-induced alterations of immune status.
The Journal of pharmacology and experimental therapeutics 1996;277(3):1533-40.
1996: Karamarie Fecho; K A Maslonek; Linda A Dykstra; Donald T Lysle
Evidence for sympathetic and adrenal involvement in the immunomodulatory effects of acute morphine treatment in rats.
The Journal of pharmacology and experimental therapeutics 1996;277(2):633-45.
1996: C E Hughes; T Habash; Linda A Dykstra; Mitchell J Picker
Discriminative-stimulus effects of morphine in combination with alpha- and beta-noradrenergic agonists and antagonists in rats.
Pharmacology, biochemistry, and behavior 1996;53(4):979-86.
1996: Karamarie Fecho; K A Maslonek; Linda A Dykstra; Donald T Lysle
Assessment of the involvement of central nervous system and peripheral opioid receptors in the immunomodulatory effects of acute morphine treatment in rats.
The Journal of pharmacology and experimental therapeutics 1996;276(2):626-36.
1995: K R Powell; Linda A Dykstra
The role of serotonin in the effects of opioids in squirrel monkeys responding under a titration procedure: I. Kappa opioids.
The Journal of pharmacology and experimental therapeutics 1995;274(3):1305-16.
1995: Karamarie Fecho; K A Maslonek; Linda A Dykstra; Donald T Lysle
Mechanisms whereby macrophage-derived nitric oxide is involved in morphine-induced suppression of splenic lymphocyte proliferation.
The Journal of pharmacology and experimental therapeutics 1995;272(2):477-83.
1995: K E Hoffman; K A Maslonek; Linda A Dykstra; Donald T Lysle
Effects of central administration of morphine on immune status in Lewis and Wistar rats.
Advances in experimental medicine and biology 1995;373():155-9.
1995: Karamarie Fecho; K A Maslonek; Linda A Dykstra; Donald T Lysle
Mechanisms whereby macrophage-derived nitric oxide is involved in morphine-induced immunomodulation.
Advances in experimental medicine and biology 1995;373():149-53.
1995: Donald T Lysle; Karamarie Fecho; K A Maslonek; Linda A Dykstra
Evidence for the involvement of macrophage-derived nitric oxide in the immunomodulatory effect of morphine and aversive Pavlovian conditioning.
Advances in experimental medicine and biology 1995;373():141-7.
1994: Raymond C Pitts; Linda A Dykstra
Antinociceptive and response rate-altering effects of kappa opioid agonists, spiradoline, enadoline and U69,593, alone and in combination with opioid antagonists in squirrel monkeys.
The Journal of pharmacology and experimental therapeutics 1994;271(3):1501-8.
1994: M E Coussons-Read; Linda A Dykstra; Donald T Lysle
Pavlovian conditioning of morphine-induced alterations of immune status: evidence for opioid receptor involvement.
Journal of neuroimmunology 1994;55(2):135-42.
1994: M E Coussons-Read; Linda A Dykstra; Donald T Lysle
Pavlovian conditioning of morphine-induced alterations of immune status: evidence for peripheral beta-adrenergic receptor involvement.
Brain, behavior, and immunity 1994;8(3):204-17.
1994: Karamarie Fecho; K A Maslonek; M E Coussons-Read; Linda A Dykstra; Donald T Lysle
Macrophage-derived nitric oxide is involved in the depressed concanavalin A responsiveness of splenic lymphocytes from rats administered morphine in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(12):5845-52.
1994: P Doty; Linda A Dykstra; Mitchell J Picker
Discriminative stimulus effects of phencyclidine: pharmacologically specific interactions with delta 9- and delta 8-tetrahydrocannabinol.
Drug and alcohol dependence 1994;35(2):151-8.
1994: adande mattox; Mitchell J Picker; Linda A Dykstra
Pharmacological analysis of the rate-decreasing effects of mu and kappa opioids in pigeons.
Psychopharmacology 1994;113(3-4):457-62.
1993: Linda A Dykstra; Geoffrey Schoenbaum; J Yarbrough; R McNutt; K J Chang
A novel delta opioid agonist, BW373U86, in squirrel monkeys responding under a schedule of shock titration.
The Journal of pharmacology and experimental therapeutics 1993;267(2):875-82.
1993: Karamarie Fecho; K A Maslonek; Linda A Dykstra; Donald T Lysle
Alterations of immune status induced by the sympathetic nervous system: immunomodulatory effects of DMPP alone and in combination with morphine.
Brain, behavior, and immunity 1993;7(3):253-70.
1993: Mitchell J Picker; J Yarbrough; C E Hughes; MA Smith; Drake Morgan; Linda A Dykstra
Agonist and antagonist effects of mixed action opioids in the pigeon drug discrimination procedure: influence of training dose, intrinsic efficacy and interanimal differences.
The Journal of pharmacology and experimental therapeutics 1993;266(2):756-67.
1993: Karamarie Fecho; Linda A Dykstra; Donald T Lysle
Evidence for beta adrenergic receptor involvement in the immunomodulatory effects of morphine.
The Journal of pharmacology and experimental therapeutics 1993;265(3):1079-87.
1993: Donald T Lysle; M E Coussons; Val Watts; E H Bennett; Linda A Dykstra
Morphine-induced alterations of immune status: dose dependency, compartment specificity and antagonism by naltrexone.
The Journal of pharmacology and experimental therapeutics 1993;265(3):1071-8.
1993: R M Craft; Linda A Dykstra
Morphine antagonizes U50,488's effects in a squirrel monkey shock titration procedure.
European journal of pharmacology 1993;234(2-3):199-207.
1993: Donald T Lysle; M E Coussons; Val Watts; E H Bennett; Linda A Dykstra
Morphine-induced modulation of immune status: evidence for opioid receptor mediation and compartment specificity.
Advances in experimental medicine and biology 1993;335():53-9.
1993: Linda A Dykstra; K R Powell; Y P Lin
Antinociceptive effects of the kappa opioid, U50,488: lack of modulation by 5-HT2 antagonists.
Psychopharmacology 1993;112(1):116-20.
1993: M E Bronson; Y P Lin; K Burchett; Mitchell J Picker; Linda A Dykstra
Serotonin involvement in the discriminative stimulus effects of kappa opioids in pigeons.
Psychopharmacology 1993;111(1):69-77.
1992: Mitchell J Picker; R M Craft; S Stevens Negus; K R Powell; adande mattox; S R Jones; B K Hargrove; Linda A Dykstra
Intermediate efficacy mu opioids: examination of their morphine-like stimulus effects and response rate-decreasing effects in morphine-tolerant rats.
The Journal of pharmacology and experimental therapeutics 1992;263(2):668-81.
1992: M E Coussons; Linda A Dykstra; Donald T Lysle
Pavlovian conditioning of morphine-induced alterations of immune status.
Journal of neuroimmunology 1992;39(3):219-30.
1992: Linda A Dykstra; P Doty; A B Johnson; Mitchell J Picker
Discriminative stimulus properties of cocaine, alone and in combination with buprenorphine, morphine and naltrexone.
Drug and alcohol dependence 1992;30(3):227-34.
1992: R M Craft; Linda A Dykstra
Agonist and antagonist activity of kappa opioids in the squirrel monkey: II. Effect of chronic morphine treatment.
The Journal of pharmacology and experimental therapeutics 1992;260(1):334-42.
1992: R M Craft; Linda A Dykstra
Agonist and antagonist activity of kappa opioids in the squirrel monkey: I. Antinociception and urine output.
The Journal of pharmacology and experimental therapeutics 1992;260(1):327-33.
1991: A H Oliveto; Mitchell J Picker; Linda A Dykstra
Acute and chronic morphine administration: effects of mixed-action opioids in rats and squirrel monkeys responding under a schedule of food presentation.
The Journal of pharmacology and experimental therapeutics 1991;257(1):8-18.
1991: S Stevens Negus; Mitchell J Picker; Linda A Dykstra
Interactions between the discriminative stimulus effects of mu and kappa opioid agonists in the squirrel monkey.
The Journal of pharmacology and experimental therapeutics 1991;256(1):149-58.
1990: Linda A Dykstra
Butorphanol, levallorphan, nalbuphine and nalorphine as antagonists in the squirrel monkey.
The Journal of pharmacology and experimental therapeutics 1990;254(1):245-52.
1990: Mitchell J Picker; P Doty; S Stevens Negus; adande mattox; Linda A Dykstra
Discriminative stimulus properties of U50,488 and morphine: effects of training dose on stimulus substitution patterns produced by mu and kappa opioid agonists.
The Journal of pharmacology and experimental therapeutics 1990;254(1):13-22.
1990: Linda A Dykstra; Mitchell J Picker; K R Powell
Opioid agonists/antagonists in morphine-tolerant squirrel monkeys.
Pharmacology, biochemistry, and behavior 1990;36(3):639-44.
1990: R M Craft; Linda A Dykstra
Differential cross-tolerance to opioids in squirrel monkeys responding under a shock titration schedule.
The Journal of pharmacology and experimental therapeutics 1990;252(3):945-52.
1990: S Stevens Negus; M J Picker; Linda A Dykstra
Interactions between mu and kappa opioid agonists in the rat drug discrimination procedure.
Psychopharmacology 1990;102(4):465-73.
1990: Linda A Dykstra; Mitchell J Picker; K Powell
Stereospecificity of mixed-action opioid agonist/antagonists in morphine-tolerant squirrel monkeys.
NIDA research monograph 1990;105():375.
1990: adande mattox; Mitchell J Picker; Linda A Dykstra
Antagonism of mu and kappa opioids: effects on schedule-controlled behavior in pigeons.
NIDA research monograph 1990;105():390.
1990: P Doty; Mitchell J Picker; Linda A Dykstra
Delta-9-THC interactions with PCP and ethanol in rats responding under a fixed consecutive number schedule.
NIDA research monograph 1990;105():299.
1989: P Doty; Mitchell J Picker; Linda A Dykstra
Differential cross-tolerance to opioid agonists in morphine-tolerant squirrel monkeys responding under a schedule of food presentation.
European journal of pharmacology 1989;174(2-3):171-80.
1989: Mitchell J Picker; Linda A Dykstra
Discriminative stimulus effects of mu and kappa opioids in the pigeon: analysis of the effects of full and partial mu and kappa agonists.
The Journal of pharmacology and experimental therapeutics 1989;249(2):557-66.
1989: R M Craft; Mitchell J Picker; Linda A Dykstra
Differential cross-tolerance to opioid agonists in morphine-tolerant pigeons responding under a schedule of food presentation.
The Journal of pharmacology and experimental therapeutics 1989;249(2):386-93.
1989: Mitchell J Picker; James P Cleary; K Berens; A H Oliveto; Linda A Dykstra
Molindone: effects in pigeons responding under conditional discrimination tasks.
Pharmacology, biochemistry, and behavior 1989;32(2):439-45.
1989: Mitchell J Picker; S Stevens Negus; Linda A Dykstra
Opioid-like discriminative stimulus properties of benzomorphans in the pigeon: stereospecificity and differential substitution patterns.
Life sciences 1989;45(18):1637-45.
1989: S Stevens Negus; M J Picker; Linda A Dykstra
Kappa antagonist properties of buprenorphine in non-tolerant and morphine-tolerant rats.
Psychopharmacology 1989;98(1):141-3.
1988: S Stevens Negus; Linda A Dykstra
Kappa antagonist properties of buprenorphine in the shock titration procedure.
European journal of pharmacology 1988;156(1):77-86.
1988: Linda A Dykstra; C A Massie
Antagonism of the analgesic effects of mu and kappa opioid agonists in the squirrel monkey.
The Journal of pharmacology and experimental therapeutics 1988;246(3):813-21.
1988: A H Oliveto; B L Slifer; Linda A Dykstra
Tripelennamine fails to enhance the morphine-like stimulus effects of pentazocine.
Pharmacology, biochemistry, and behavior 1988;29(2):397-401.
1988: A H Oliveto; Linda A Dykstra
Diprenorphine and naloxone in squirrel monkeys with enhanced sensitivity to opioid antagonists.
Psychopharmacology 1988;95(3):339-43.
1988: Linda A Dykstra; A J Bertalmio; J H Woods
Discriminative and analgesic effects of mu and kappa opioids: in vivo pA2 analysis.
Psychopharmacology series 1988;4():107-21.
1988: Mitchell J Picker; Linda A Dykstra
Differential effects of opioid and nonopioid analgesics on conditional discriminations in pigeons.
Psychopharmacology 1988;94(3):405-11.
1987: Mitchell J Picker; Linda A Dykstra
Comparison of the discriminative stimulus properties of U50,488 and morphine in pigeons.
The Journal of pharmacology and experimental therapeutics 1987;243(3):938-45.
1987: B L Slifer; Linda A Dykstra
Discriminative stimulus effects of N-allylnormetazocine in rats trained to discriminate a kappa from a sigma agonist.
Life sciences 1987;40(4):343-9.
1987: B L Slifer; Linda A Dykstra
The effects of N-allylnormetazocine on electric shock titration in squirrel monkeys.
Alcohol and drug research 1987;7(4):217-24.
1987: Mitchell J Picker; C A Massie; Linda A Dykstra
Evaluation of the effects of opioid agonists and antagonists under a delayed matching-to-sample procedure in pigeons.
Psychopharmacology 1987;93(2):230-6.